EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000162664 (Gene tree)
Gene ID: 284695
Gene Symbol: ZNF326
Alias: Zfp326|ZAN75|FLJ20403|ZIRD
Full Name: zinc finger protein 326
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 40,420 bases
Position: chr1:89,995,112-90,035,531
Accession: 14104
RBP type: canonical RBP
Summary: (Zinc Finger Protein 326) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA polymerase II complex binding. An important paralog of this gene is AKAP8.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000359476	AKAP95	PF04988.12	8.5e-75	1	1
ENSP00000340796	AKAP95	PF04988.12	1.2e-74	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000361911	ZNF326-202	1538	-	ENSP00000355318	70 (aa)	-	Q5BKZ1
ENST00000394583	ZNF326-204	1956	-	ENSP00000378084	53 (aa)	-	E2QRN4
ENST00000370447	ZNF326-203	9433	XM_005270779	ENSP00000359476	493 (aa)	XP_005270836	A0A0A0MRN4
ENST00000340281	ZNF326-201	2729	-	ENSP00000340796	582 (aa)	-	Q5BKZ1

Gene Model

Click here to download ENSG00000162664's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000162664	Aorta	1.39225308427772E-6	17903303
ENSG00000162664	C-Reactive Protein	1.99902201805102E-5	17903293
ENSG00000162664	Alcoholism	8.28E-05	-
ENSG00000162664	Alcoholism	2.75E-05	-
ENSG00000162664	Alcoholism	5.1E-05	-
ENSG00000162664	Body Height	7.4080000E-005	-
ENSG00000162664	Body Height	3.7690000E-005	-
ENSG00000162664	Coronary Artery Disease	8.6970000E-005	-
ENSG00000162664	Blood Pressure	7.9700000E-005	-
ENSG00000162664	Fibrinogen	8.5630000E-005	-
ENSG00000162664	Fibrinogen	4.2110000E-005	-
ENSG00000162664	Fibrinogen	2.5840000E-005	-
ENSG00000162664	Cell Adhesion Molecules	4.9860000E-005	-
ENSG00000162664	Cell Adhesion Molecules	4.9860000E-005	-
ENSG00000162664	Platelet Function Tests	2.2204460E-016	-
ENSG00000162664	Cholesterol, HDL	1.8040000E-006	-
ENSG00000162664	Cholesterol, HDL	1.2050000E-006	-
ENSG00000162664	Coronary Disease	8.9960000E-006	-
ENSG00000162664	Coronary Disease	4.8620000E-006	-
ENSG00000162664	Coronary Disease	1.8580000E-006	-
ENSG00000162664	Coronary Disease	2.3140000E-006	-
ENSG00000162664	Coronary Disease	3.9830000E-006	-
ENSG00000162664	Coronary Disease	3.1240000E-006	-
ENSG00000162664	Coronary Disease	1.0890000E-005	-
ENSG00000162664	Coronary Disease	3.6400000E-006	-
ENSG00000162664	Coronary Disease	3.0580000E-006	-
ENSG00000162664	Coronary Disease	3.5440000E-006	-
ENSG00000162664	Coronary Disease	1.0280000E-005	-
ENSG00000162664	Paliperidone Palmitate	7E-6	27846195
ENSG00000162664	Schizophrenia	7E-6	27846195
ENSG00000162664	Essential Tremor	4E-7	27797806
ENSG00000162664	Vascular Calcification	1E-6	17903303
ENSG00000162664	Brain Mapping	2E-6	20197096
ENSG00000162664	Hippocampus	2E-6	20197096
ENSG00000162664	Paliperidone Palmitate	9E-6	27846195
ENSG00000162664	Schizophrenia	9E-6	27846195
ENSG00000162664	Antidepressive Agents	4E-7	20360315

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000162664's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000162664	ZNF326	93	100.000	ENSAMEG00000000495	ZNF326	83	98.742	Ailuropoda_melanoleuca
ENSG00000162664	ZNF326	67	32.344	ENSAOCG00000022319	akap8l	64	30.787	Amphiprion_ocellaris
ENSG00000162664	ZNF326	67	32.344	ENSAPEG00000009544	akap8l	64	30.787	Amphiprion_percula
ENSG00000162664	ZNF326	77	78.024	ENSAPLG00000015720	ZNF326	92	77.689	Anas_platyrhynchos
ENSG00000162664	ZNF326	79	79.310	ENSACAG00000001151	ZNF326	89	75.595	Anolis_carolinensis
ENSG00000162664	ZNF326	100	100.000	ENSANAG00000019477	ZNF326	100	97.595	Aotus_nancymaae
ENSG00000162664	ZNF326	71	46.348	ENSAMXG00000037522	znf326	77	45.706	Astyanax_mexicanus
ENSG00000162664	ZNF326	100	98.571	ENSBTAG00000019133	ZNF326	83	97.718	Bos_taurus
ENSG00000162664	ZNF326	100	100.000	ENSCJAG00000001897	ZNF326	100	97.766	Callithrix_jacchus
ENSG00000162664	ZNF326	93	100.000	ENSCAFG00000020195	ZNF326	82	97.904	Canis_familiaris
ENSG00000162664	ZNF326	100	100.000	ENSCAFG00020013621	ZNF326	82	97.925	Canis_lupus_dingo
ENSG00000162664	ZNF326	100	98.571	ENSCHIG00000017408	ZNF326	83	97.925	Capra_hircus
ENSG00000162664	ZNF326	100	100.000	ENSTSYG00000004872	ZNF326	100	89.708	Carlito_syrichta
ENSG00000162664	ZNF326	76	97.561	ENSCAPG00000006362	ZNF326	99	74.656	Cavia_aperea
ENSG00000162664	ZNF326	79	97.614	ENSCPOG00000007332	ZNF326	82	97.614	Cavia_porcellus
ENSG00000162664	ZNF326	100	100.000	ENSCCAG00000029464	ZNF326	100	97.595	Cebus_capucinus
ENSG00000162664	ZNF326	100	98.571	ENSCATG00000045193	ZNF326	100	97.938	Cercocebus_atys
ENSG00000162664	ZNF326	100	97.143	ENSCLAG00000004446	ZNF326	86	97.303	Chinchilla_lanigera
ENSG00000162664	ZNF326	100	98.571	ENSCSAG00000001456	ZNF326	100	98.454	Chlorocebus_sabaeus
ENSG00000162664	ZNF326	93	93.846	ENSCHOG00000012127	ZNF326	59	96.970	Choloepus_hoffmanni
ENSG00000162664	ZNF326	80	84.746	ENSCPBG00000015682	ZNF326	91	85.590	Chrysemys_picta_bellii
ENSG00000162664	ZNF326	55	67.766	ENSCANG00000039522	-	100	69.963	Colobus_angolensis_palliatus
ENSG00000162664	ZNF326	100	98.110	ENSCANG00000042982	ZNF326	100	98.110	Colobus_angolensis_palliatus
ENSG00000162664	ZNF326	81	93.658	ENSCGRG00001001292	Zfp326	81	93.709	Cricetulus_griseus_chok1gshd
ENSG00000162664	ZNF326	91	93.750	ENSCGRG00000007894	Zfp326	83	93.487	Cricetulus_griseus_crigri
ENSG00000162664	ZNF326	64	46.201	ENSDARG00000098348	znf326	92	40.185	Danio_rerio
ENSG00000162664	ZNF326	100	100.000	ENSDNOG00000039942	ZNF326	79	96.680	Dasypus_novemcinctus
ENSG00000162664	ZNF326	81	86.596	ENSDORG00000014049	Zfp326	83	87.029	Dipodomys_ordii
ENSG00000162664	ZNF326	89	95.161	ENSETEG00000010452	ZNF326	66	95.161	Echinops_telfairi
ENSG00000162664	ZNF326	77	97.763	ENSEASG00005015418	ZNF326	95	97.763	Equus_asinus_asinus
ENSG00000162664	ZNF326	100	94.286	ENSECAG00000010425	ZNF326	81	96.888	Equus_caballus
ENSG00000162664	ZNF326	100	98.571	ENSEEUG00000001861	ZNF326	99	95.021	Erinaceus_europaeus
ENSG00000162664	ZNF326	81	33.493	ENSELUG00000012410	akap8l	69	31.900	Esox_lucius
ENSG00000162664	ZNF326	100	100.000	ENSFCAG00000030586	ZNF326	82	98.755	Felis_catus
ENSG00000162664	ZNF326	77	78.831	ENSFALG00000001671	ZNF326	89	78.486	Ficedula_albicollis
ENSG00000162664	ZNF326	76	100.000	ENSFDAG00000014243	ZNF326	79	100.000	Fukomys_damarensis
ENSG00000162664	ZNF326	77	77.823	ENSGALG00000006113	ZNF326	89	77.888	Gallus_gallus
ENSG00000162664	ZNF326	52	33.083	ENSGACG00000019873	akap8l	58	37.952	Gasterosteus_aculeatus
ENSG00000162664	ZNF326	74	86.207	ENSGAGG00000014287	ZNF326	89	80.533	Gopherus_agassizii
ENSG00000162664	ZNF326	100	100.000	ENSGGOG00000015528	ZNF326	100	99.828	Gorilla_gorilla
ENSG00000162664	ZNF326	100	98.571	ENSHGLG00000004782	ZNF326	86	97.925	Heterocephalus_glaber_female
ENSG00000162664	ZNF326	96	100.000	ENSHGLG00100002583	ZNF326	85	98.048	Heterocephalus_glaber_male
ENSG00000162664	ZNF326	69	44.220	ENSIPUG00000012682	znf326	66	43.827	Ictalurus_punctatus
ENSG00000162664	ZNF326	100	100.000	ENSSTOG00000005176	ZNF326	86	98.963	Ictidomys_tridecemlineatus
ENSG00000162664	ZNF326	100	91.429	ENSJJAG00000019314	Zfp326	85	94.813	Jaculus_jaculus
ENSG00000162664	ZNF326	70	31.445	ENSLBEG00000010793	akap8l	66	31.136	Labrus_bergylta
ENSG00000162664	ZNF326	76	62.319	ENSLACG00000012654	ZNF326	95	66.593	Latimeria_chalumnae
ENSG00000162664	ZNF326	77	56.140	ENSLOCG00000004998	znf326	86	61.017	Lepisosteus_oculatus
ENSG00000162664	ZNF326	100	95.714	ENSLAFG00000007871	ZNF326	86	91.892	Loxodonta_africana
ENSG00000162664	ZNF326	100	98.571	ENSMFAG00000044308	ZNF326	100	98.454	Macaca_fascicularis
ENSG00000162664	ZNF326	100	98.174	ENSMMUG00000003442	ZNF326	100	98.174	Macaca_mulatta
ENSG00000162664	ZNF326	100	98.571	ENSMNEG00000030833	ZNF326	100	98.454	Macaca_nemestrina
ENSG00000162664	ZNF326	100	98.571	ENSMLEG00000028429	ZNF326	100	98.282	Mandrillus_leucophaeus
ENSG00000162664	ZNF326	79	77.515	ENSMGAG00000008473	ZNF326	89	77.888	Meleagris_gallopavo
ENSG00000162664	ZNF326	89	91.935	ENSMAUG00000020840	Zfp326	82	92.739	Mesocricetus_auratus
ENSG00000162664	ZNF326	100	100.000	ENSMICG00000016516	ZNF326	84	98.963	Microcebus_murinus
ENSG00000162664	ZNF326	100	95.714	ENSMOCG00000002827	Zfp326	83	94.813	Microtus_ochrogaster
ENSG00000162664	ZNF326	81	85.232	ENSMODG00000012064	ZNF326	90	85.931	Monodelphis_domestica
ENSG00000162664	ZNF326	100	91.429	MGP_CAROLIEiJ_G0027493	Zfp326	95	91.858	Mus_caroli
ENSG00000162664	ZNF326	100	91.429	ENSMUSG00000029290	Zfp326	95	92.112	Mus_musculus
ENSG00000162664	ZNF326	100	91.429	MGP_PahariEiJ_G0017265	-	95	92.112	Mus_pahari
ENSG00000162664	ZNF326	100	92.857	MGP_SPRETEiJ_G0028491	Zfp326	95	92.366	Mus_spretus
ENSG00000162664	ZNF326	100	100.000	ENSMPUG00000004655	ZNF326	82	98.755	Mustela_putorius_furo
ENSG00000162664	ZNF326	100	100.000	ENSMLUG00000004873	ZNF326	84	85.626	Myotis_lucifugus
ENSG00000162664	ZNF326	100	95.714	ENSNGAG00000019330	Zfp326	84	95.436	Nannospalax_galili
ENSG00000162664	ZNF326	100	100.000	ENSNLEG00000010263	ZNF326	100	97.938	Nomascus_leucogenys
ENSG00000162664	ZNF326	71	83.493	ENSMEUG00000011138	ZNF326	84	83.732	Notamacropus_eugenii
ENSG00000162664	ZNF326	93	89.231	ENSOPRG00000000388	ZNF326	72	92.486	Ochotona_princeps
ENSG00000162664	ZNF326	93	98.462	ENSODEG00000005953	-	83	97.484	Octodon_degus
ENSG00000162664	ZNF326	81	75.439	ENSODEG00000008358	-	79	81.529	Octodon_degus
ENSG00000162664	ZNF326	100	94.286	ENSODEG00000013679	-	83	86.100	Octodon_degus
ENSG00000162664	ZNF326	80	90.929	ENSOANG00000009225	ZNF326	94	91.126	Ornithorhynchus_anatinus
ENSG00000162664	ZNF326	100	100.000	ENSOCUG00000012291	ZNF326	100	96.429	Oryctolagus_cuniculus
ENSG00000162664	ZNF326	77	97.333	ENSOGAG00000013770	ZNF326	90	97.333	Otolemur_garnettii
ENSG00000162664	ZNF326	93	98.462	ENSOARG00000015643	ZNF326	83	97.904	Ovis_aries
ENSG00000162664	ZNF326	97	99.467	ENSPPAG00000014161	ZNF326	100	99.643	Pan_paniscus
ENSG00000162664	ZNF326	100	100.000	ENSPPRG00000006384	ZNF326	82	98.755	Panthera_pardus
ENSG00000162664	ZNF326	91	100.000	ENSPTIG00000019259	ZNF326	81	98.739	Panthera_tigris_altaica
ENSG00000162664	ZNF326	100	100.000	ENSPTRG00000000945	ZNF326	100	99.828	Pan_troglodytes
ENSG00000162664	ZNF326	100	98.571	ENSPANG00000023228	ZNF326	100	98.110	Papio_anubis
ENSG00000162664	ZNF326	83	84.211	ENSPSIG00000002449	ZNF326	94	84.648	Pelodiscus_sinensis
ENSG00000162664	ZNF326	84	92.464	ENSPEMG00000018327	Zfp326	81	93.966	Peromyscus_maniculatus_bairdii
ENSG00000162664	ZNF326	100	87.143	ENSPPYG00000001166	ZNF326	100	83.447	Pongo_abelii
ENSG00000162664	ZNF326	93	96.923	ENSPCAG00000015388	ZNF326	65	100.000	Procavia_capensis
ENSG00000162664	ZNF326	100	100.000	ENSPCOG00000023736	ZNF326	84	98.755	Propithecus_coquereli
ENSG00000162664	ZNF326	93	100.000	ENSPVAG00000016778	ZNF326	99	83.077	Pteropus_vampyrus
ENSG00000162664	ZNF326	63	43.963	ENSPNAG00000000876	znf326	76	42.149	Pygocentrus_nattereri
ENSG00000162664	ZNF326	81	89.474	ENSRNOG00000047761	Zfp326	94	85.084	Rattus_norvegicus
ENSG00000162664	ZNF326	100	97.143	ENSRBIG00000028780	ZNF326	100	87.801	Rhinopithecus_bieti
ENSG00000162664	ZNF326	100	97.251	ENSRROG00000032091	ZNF326	100	97.251	Rhinopithecus_roxellana
ENSG00000162664	ZNF326	99	96.360	ENSSBOG00000034170	ZNF326	94	96.360	Saimiri_boliviensis_boliviensis
ENSG00000162664	ZNF326	84	82.897	ENSSHAG00000017816	ZNF326	91	83.299	Sarcophilus_harrisii
ENSG00000162664	ZNF326	85	38.462	ENSSFOG00015020009	znf326	61	40.831	Scleropages_formosus
ENSG00000162664	ZNF326	100	85.077	ENSSARG00000003044	ZNF326	84	94.191	Sorex_araneus
ENSG00000162664	ZNF326	78	81.420	ENSSPUG00000001848	ZNF326	93	81.992	Sphenodon_punctatus
ENSG00000162664	ZNF326	82	95.388	ENSSSCG00000038253	ZNF326	75	96.104	Sus_scrofa
ENSG00000162664	ZNF326	77	78.427	ENSTGUG00000006205	ZNF326	89	78.088	Taeniopygia_guttata
ENSG00000162664	ZNF326	80	96.154	ENSTBEG00000002416	ZNF326	96	73.319	Tupaia_belangeri
ENSG00000162664	ZNF326	82	95.388	ENSTTRG00000004227	ZNF326	82	95.388	Tursiops_truncatus
ENSG00000162664	ZNF326	100	100.000	ENSUAMG00000021637	ZNF326	82	98.755	Ursus_americanus
ENSG00000162664	ZNF326	79	98.698	ENSUMAG00000001464	ZNF326	82	98.698	Ursus_maritimus
ENSG00000162664	ZNF326	79	83.766	ENSVPAG00000010657	ZNF326	100	83.766	Vicugna_pacos
ENSG00000162664	ZNF326	79	97.831	ENSVVUG00000030223	ZNF326	84	97.831	Vulpes_vulpes
ENSG00000162664	ZNF326	83	67.288	ENSXETG00000006087	znf326	92	70.312	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000993	RNA polymerase II complex binding	21873635.	IBA	Function
GO:0000993	RNA polymerase II complex binding	22446626.	IDA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	22446626.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0016363	nuclear matrix	21873635.	IBA	Component
GO:0032784	regulation of DNA-templated transcription, elongation	21873635.	IBA	Process
GO:0032784	regulation of DNA-templated transcription, elongation	22446626.	IMP	Process
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0043484	regulation of RNA splicing	22446626.	IMP	Process
GO:0044609	DBIRD complex	21873635.	IBA	Component
GO:0044609	DBIRD complex	22446626.	IDA	Component
GO:0046872	metal ion binding	-	IEA	Function