EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000162782 (Gene tree)
Gene ID: 163589
Gene Symbol: TDRD5
Alias: FLJ34823|TUDOR3
Full Name: tudor domain containing 5
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 99,660 bases
Position: chr1:179,591,613-179,691,272
Accession: 20614
RBP type: canonical RBP
Summary: (Tudor Domain Containing 5) is a Protein Coding gene. An important paralog of this gene is TDRD6.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000294848	TUDOR	PF00567.24	7.2e-21	1	1
ENSP00000356586	TUDOR	PF00567.24	7.2e-21	1	1
ENSP00000406052	TUDOR	PF00567.24	7.6e-21	1	1
ENSP00000410744	TUDOR	PF00567.24	2.3e-05	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29317670	TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.	Nat Commun	2018 Jan 9	Ding D	doi: 10.1038/s41467-017-02622-w.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000444136	TDRD5-204	3946	XM_005244934	ENSP00000406052	1035 (aa)	XP_005244991	Q8NAT2
ENST00000417329	TDRD5-203	1805	-	ENSP00000410744	491 (aa)	-	A0A0C4DG74
ENST00000367614	TDRD5-202	3632	-	ENSP00000356586	981 (aa)	-	Q8NAT2
ENST00000294848	TDRD5-201	3525	-	ENSP00000294848	981 (aa)	-	Q8NAT2

Gene Model

Click here to download ENSG00000162782's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000162782	Body Weight	8.3543782868123E-5	17903300
ENSG00000162782	Body Weight	3.33930811104999E-5	17903300
ENSG00000162782	Body Weight	6.46942529538563E-5	17903300
ENSG00000162782	Platelet Function Tests	2.2204460E-016	-
ENSG00000162782	Platelet Function Tests	2.2204460E-016	-
ENSG00000162782	Platelet Function Tests	2.2204460E-016	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000162782	rs12070589	1	179593572	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000162782	rs150816167	1	179602727	T	Diastolic blood pressure	30224653	[0.2-0.37] mmHg decrease	0.2873	EFO_0006336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000162782's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000162782	TDRD5	67	40.654	ENSAPOG00000021687	-	91	34.963	Acanthochromis_polyacanthus
ENSG00000162782	TDRD5	99	84.306	ENSAMEG00000014736	TDRD5	100	84.306	Ailuropoda_melanoleuca
ENSG00000162782	TDRD5	57	41.509	ENSACIG00000009310	-	70	41.509	Amphilophus_citrinellus
ENSG00000162782	TDRD5	71	32.704	ENSAOCG00000002427	-	84	32.746	Amphiprion_ocellaris
ENSG00000162782	TDRD5	69	34.444	ENSAPEG00000006682	-	84	34.492	Amphiprion_percula
ENSG00000162782	TDRD5	69	33.287	ENSATEG00000017002	-	84	33.287	Anabas_testudineus
ENSG00000162782	TDRD5	70	51.471	ENSACAG00000001245	TDRD5	99	51.471	Anolis_carolinensis
ENSG00000162782	TDRD5	100	92.181	ENSANAG00000034635	TDRD5	100	92.181	Aotus_nancymaae
ENSG00000162782	TDRD5	76	32.080	ENSACLG00000013433	-	88	31.242	Astatotilapia_calliptera
ENSG00000162782	TDRD5	69	35.949	ENSAMXG00000017846	-	72	35.949	Astyanax_mexicanus
ENSG00000162782	TDRD5	100	84.420	ENSBTAG00000002407	TDRD5	100	84.420	Bos_taurus
ENSG00000162782	TDRD5	100	91.884	ENSCJAG00000008098	TDRD5	100	91.884	Callithrix_jacchus
ENSG00000162782	TDRD5	100	83.222	ENSCAFG00000013822	TDRD5	100	83.222	Canis_familiaris
ENSG00000162782	TDRD5	100	85.234	ENSCAFG00020016570	TDRD5	100	85.234	Canis_lupus_dingo
ENSG00000162782	TDRD5	100	84.318	ENSCHIG00000026884	TDRD5	100	84.318	Capra_hircus
ENSG00000162782	TDRD5	100	84.114	ENSTSYG00000010362	TDRD5	100	84.114	Carlito_syrichta
ENSG00000162782	TDRD5	100	92.947	ENSCCAG00000029807	TDRD5	100	92.947	Cebus_capucinus
ENSG00000162782	TDRD5	100	95.849	ENSCATG00000042714	TDRD5	100	95.849	Cercocebus_atys
ENSG00000162782	TDRD5	100	77.992	ENSCLAG00000012916	TDRD5	100	77.992	Chinchilla_lanigera
ENSG00000162782	TDRD5	100	96.024	ENSCSAG00000012216	TDRD5	100	96.024	Chlorocebus_sabaeus
ENSG00000162782	TDRD5	99	50.234	ENSCPBG00000025813	TDRD5	99	50.327	Chrysemys_picta_bellii
ENSG00000162782	TDRD5	100	95.169	ENSCANG00000037620	TDRD5	100	95.169	Colobus_angolensis_palliatus
ENSG00000162782	TDRD5	99	78.435	ENSCGRG00001012501	Tdrd5	99	78.435	Cricetulus_griseus_chok1gshd
ENSG00000162782	TDRD5	99	78.435	ENSCGRG00000007804	Tdrd5	99	78.435	Cricetulus_griseus_crigri
ENSG00000162782	TDRD5	69	34.642	ENSCSEG00000016358	-	85	34.642	Cynoglossus_semilaevis
ENSG00000162782	TDRD5	67	33.185	ENSCVAG00000015014	-	98	33.433	Cyprinodon_variegatus
ENSG00000162782	TDRD5	100	78.049	ENSDNOG00000014678	TDRD5	100	77.085	Dasypus_novemcinctus
ENSG00000162782	TDRD5	93	77.500	ENSETEG00000016819	TDRD5	93	77.500	Echinops_telfairi
ENSG00000162782	TDRD5	100	84.012	ENSEASG00005016637	TDRD5	100	84.012	Equus_asinus_asinus
ENSG00000162782	TDRD5	100	82.696	ENSECAG00000017037	TDRD5	100	82.156	Equus_caballus
ENSG00000162782	TDRD5	100	76.656	ENSEEUG00000003054	TDRD5	94	86.057	Erinaceus_europaeus
ENSG00000162782	TDRD5	69	35.765	ENSELUG00000003097	-	81	36.041	Esox_lucius
ENSG00000162782	TDRD5	99	84.008	ENSFCAG00000001806	TDRD5	99	84.008	Felis_catus
ENSG00000162782	TDRD5	98	76.908	ENSFDAG00000005189	TDRD5	99	76.650	Fukomys_damarensis
ENSG00000162782	TDRD5	66	40.196	ENSFHEG00000003128	-	94	40.196	Fundulus_heteroclitus
ENSG00000162782	TDRD5	65	51.456	ENSGALG00000033634	TDRD5	83	51.456	Gallus_gallus
ENSG00000162782	TDRD5	69	33.288	ENSGAFG00000006838	-	91	33.288	Gambusia_affinis
ENSG00000162782	TDRD5	91	56.657	ENSGAGG00000017788	TDRD5	96	55.334	Gopherus_agassizii
ENSG00000162782	TDRD5	100	98.982	ENSGGOG00000011310	TDRD5	100	98.777	Gorilla_gorilla
ENSG00000162782	TDRD5	76	32.282	ENSHBUG00000018309	-	88	31.566	Haplochromis_burtoni
ENSG00000162782	TDRD5	100	76.171	ENSHGLG00100002899	-	100	76.045	Heterocephalus_glaber_male
ENSG00000162782	TDRD5	68	32.941	ENSHCOG00000018949	-	86	32.941	Hippocampus_comes
ENSG00000162782	TDRD5	69	36.888	ENSIPUG00000025087	tdrd5	75	37.213	Ictalurus_punctatus
ENSG00000162782	TDRD5	100	82.347	ENSSTOG00000026328	TDRD5	100	82.347	Ictidomys_tridecemlineatus
ENSG00000162782	TDRD5	99	78.065	ENSJJAG00000024411	Tdrd5	99	78.065	Jaculus_jaculus
ENSG00000162782	TDRD5	58	33.162	ENSKMAG00000004523	-	99	33.333	Kryptolebias_marmoratus
ENSG00000162782	TDRD5	71	33.469	ENSLBEG00000027480	-	97	33.469	Labrus_bergylta
ENSG00000162782	TDRD5	67	46.617	ENSLACG00000005749	TDRD5	100	46.617	Latimeria_chalumnae
ENSG00000162782	TDRD5	66	35.337	ENSLOCG00000009071	-	99	35.337	Lepisosteus_oculatus
ENSG00000162782	TDRD5	99	81.053	ENSLAFG00000015295	TDRD5	100	81.053	Loxodonta_africana
ENSG00000162782	TDRD5	100	95.753	ENSMFAG00000045587	TDRD5	100	95.753	Macaca_fascicularis
ENSG00000162782	TDRD5	100	95.753	ENSMMUG00000016033	TDRD5	100	95.753	Macaca_mulatta
ENSG00000162782	TDRD5	100	95.753	ENSMNEG00000030554	TDRD5	100	95.753	Macaca_nemestrina
ENSG00000162782	TDRD5	100	95.656	ENSMLEG00000043004	TDRD5	100	95.656	Mandrillus_leucophaeus
ENSG00000162782	TDRD5	69	34.813	ENSMAMG00000006700	-	80	34.813	Mastacembelus_armatus
ENSG00000162782	TDRD5	59	37.662	ENSMZEG00005009928	-	80	37.662	Maylandia_zebra
ENSG00000162782	TDRD5	74	31.250	ENSMZEG00005018676	-	88	30.378	Maylandia_zebra
ENSG00000162782	TDRD5	99	77.481	ENSMAUG00000022134	Tdrd5	99	77.481	Mesocricetus_auratus
ENSG00000162782	TDRD5	100	86.544	ENSMICG00000017589	TDRD5	100	86.544	Microcebus_murinus
ENSG00000162782	TDRD5	99	73.589	ENSMOCG00000005624	Tdrd5	98	73.589	Microtus_ochrogaster
ENSG00000162782	TDRD5	68	35.294	ENSMMOG00000007174	-	85	35.235	Mola_mola
ENSG00000162782	TDRD5	100	63.828	ENSMODG00000006180	TDRD5	100	63.919	Monodelphis_domestica
ENSG00000162782	TDRD5	69	32.917	ENSMALG00000017614	-	93	33.333	Monopterus_albus
ENSG00000162782	TDRD5	100	76.667	MGP_CAROLIEiJ_G0014733	Tdrd5	99	76.667	Mus_caroli
ENSG00000162782	TDRD5	100	77.333	ENSMUSG00000060985	Tdrd5	99	77.333	Mus_musculus
ENSG00000162782	TDRD5	99	75.383	MGP_PahariEiJ_G0027969	Tdrd5	99	75.383	Mus_pahari
ENSG00000162782	TDRD5	100	76.667	MGP_SPRETEiJ_G0015540	Tdrd5	99	76.667	Mus_spretus
ENSG00000162782	TDRD5	100	83.603	ENSMPUG00000005232	TDRD5	100	83.603	Mustela_putorius_furo
ENSG00000162782	TDRD5	99	81.089	ENSMLUG00000010369	TDRD5	100	81.089	Myotis_lucifugus
ENSG00000162782	TDRD5	99	79.119	ENSNGAG00000016603	Tdrd5	99	79.119	Nannospalax_galili
ENSG00000162782	TDRD5	69	32.821	ENSNBRG00000022619	-	87	32.821	Neolamprologus_brichardi
ENSG00000162782	TDRD5	100	97.149	ENSNLEG00000015751	TDRD5	100	97.146	Nomascus_leucogenys
ENSG00000162782	TDRD5	70	87.037	ENSMEUG00000012055	-	70	87.037	Notamacropus_eugenii
ENSG00000162782	TDRD5	77	86.364	ENSOPRG00000014271	-	93	67.134	Ochotona_princeps
ENSG00000162782	TDRD5	72	31.345	ENSONIG00000014143	-	88	35.233	Oreochromis_niloticus
ENSG00000162782	TDRD5	100	61.862	ENSOANG00000000964	TDRD5	100	61.862	Ornithorhynchus_anatinus
ENSG00000162782	TDRD5	100	78.032	ENSOCUG00000000491	TDRD5	99	78.107	Oryctolagus_cuniculus
ENSG00000162782	TDRD5	68	35.193	ENSORLG00000025711	-	76	35.193	Oryzias_latipes
ENSG00000162782	TDRD5	68	35.479	ENSORLG00020014234	-	88	34.488	Oryzias_latipes_hni
ENSG00000162782	TDRD5	68	35.562	ENSORLG00015009546	-	76	35.562	Oryzias_latipes_hsok
ENSG00000162782	TDRD5	69	33.567	ENSOMEG00000004366	-	80	33.567	Oryzias_melastigma
ENSG00000162782	TDRD5	100	84.971	ENSOGAG00000008026	TDRD5	100	84.971	Otolemur_garnettii
ENSG00000162782	TDRD5	100	83.734	ENSOARG00000017299	TDRD5	100	83.734	Ovis_aries
ENSG00000162782	TDRD5	100	99.796	ENSPPAG00000034442	TDRD5	100	99.034	Pan_paniscus
ENSG00000162782	TDRD5	100	85.031	ENSPPRG00000020775	TDRD5	100	85.031	Panthera_pardus
ENSG00000162782	TDRD5	99	84.275	ENSPTIG00000019375	TDRD5	99	84.275	Panthera_tigris_altaica
ENSG00000162782	TDRD5	100	99.796	ENSPTRG00000001732	TDRD5	100	99.034	Pan_troglodytes
ENSG00000162782	TDRD5	100	93.340	ENSPANG00000021218	TDRD5	100	93.340	Papio_anubis
ENSG00000162782	TDRD5	75	35.398	ENSPKIG00000003193	-	83	35.398	Paramormyrops_kingsleyae
ENSG00000162782	TDRD5	59	53.596	ENSPSIG00000010940	TDRD5	95	53.596	Pelodiscus_sinensis
ENSG00000162782	TDRD5	59	42.544	ENSPMGG00000017309	-	77	40.741	Periophthalmus_magnuspinnatus
ENSG00000162782	TDRD5	100	64.909	ENSPCIG00000011517	TDRD5	100	65.484	Phascolarctos_cinereus
ENSG00000162782	TDRD5	69	34.648	ENSPFOG00000015890	-	99	34.648	Poecilia_formosa
ENSG00000162782	TDRD5	71	33.069	ENSPLAG00000012088	-	96	33.069	Poecilia_latipinna
ENSG00000162782	TDRD5	69	33.424	ENSPMEG00000015988	-	79	33.424	Poecilia_mexicana
ENSG00000162782	TDRD5	70	34.037	ENSPREG00000012178	-	95	33.778	Poecilia_reticulata
ENSG00000162782	TDRD5	100	92.355	ENSPPYG00000000460	TDRD5	100	92.355	Pongo_abelii
ENSG00000162782	TDRD5	100	84.302	ENSPCOG00000017971	TDRD5	100	84.302	Propithecus_coquereli
ENSG00000162782	TDRD5	100	80.570	ENSPVAG00000012203	TDRD5	100	80.570	Pteropus_vampyrus
ENSG00000162782	TDRD5	69	32.545	ENSPNYG00000014549	-	85	32.545	Pundamilia_nyererei
ENSG00000162782	TDRD5	99	32.572	ENSPNAG00000020990	-	75	36.917	Pygocentrus_nattereri
ENSG00000162782	TDRD5	99	78.161	ENSRNOG00000004018	Tdrd5	98	84.892	Rattus_norvegicus
ENSG00000162782	TDRD5	100	95.923	ENSRBIG00000027790	TDRD5	100	95.923	Rhinopithecus_bieti
ENSG00000162782	TDRD5	100	95.923	ENSRROG00000045389	TDRD5	100	95.923	Rhinopithecus_roxellana
ENSG00000162782	TDRD5	100	91.884	ENSSBOG00000007387	TDRD5	100	91.884	Saimiri_boliviensis_boliviensis
ENSG00000162782	TDRD5	100	65.777	ENSSHAG00000001552	TDRD5	100	66.349	Sarcophilus_harrisii
ENSG00000162782	TDRD5	63	41.553	ENSSFOG00015018451	-	99	41.553	Scleropages_formosus
ENSG00000162782	TDRD5	69	33.241	ENSSMAG00000020999	-	88	33.241	Scophthalmus_maximus
ENSG00000162782	TDRD5	70	35.054	ENSSDUG00000010066	-	89	33.969	Seriola_dumerili
ENSG00000162782	TDRD5	70	34.979	ENSSLDG00000001877	-	91	33.890	Seriola_lalandi_dorsalis
ENSG00000162782	TDRD5	68	50.882	ENSSPUG00000017982	TDRD5	97	51.180	Sphenodon_punctatus
ENSG00000162782	TDRD5	69	33.380	ENSSPAG00000006013	-	86	33.380	Stegastes_partitus
ENSG00000162782	TDRD5	81	84.688	ENSSSCG00000015527	TDRD5	99	84.688	Sus_scrofa
ENSG00000162782	TDRD5	69	35.007	ENSTRUG00000001601	-	82	35.007	Takifugu_rubripes
ENSG00000162782	TDRD5	67	34.375	ENSTNIG00000010172	-	99	34.524	Tetraodon_nigroviridis
ENSG00000162782	TDRD5	100	80.652	ENSTTRG00000013250	TDRD5	100	80.652	Tursiops_truncatus
ENSG00000162782	TDRD5	98	86.128	ENSUMAG00000020642	TDRD5	99	86.128	Ursus_maritimus
ENSG00000162782	TDRD5	100	83.719	ENSVVUG00000012444	TDRD5	100	83.719	Vulpes_vulpes
ENSG00000162782	TDRD5	99	34.943	ENSXETG00000029942	TDRD5	99	42.493	Xenopus_tropicalis
ENSG00000162782	TDRD5	67	33.876	ENSXMAG00000026146	-	83	33.876	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0007286	spermatid development	-	ISS	Process
GO:0030719	P granule organization	-	ISS	Process
GO:0033391	chromatoid body	-	ISS	Component
GO:0043046	DNA methylation involved in gamete generation	-	ISS	Process
GO:0071546	pi-body	-	ISS	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr1	179587697	5'Flank	novel		0.93
ACC	chr1	179652071	Silent	novel	Y678Y	0.91
ACC	chr1	179650951	Missense_Mutation	NA	D629N	0.27
BLCA	chr1	179588707	5'Flank	novel		0.19
BLCA	chr1	179595676	Missense_Mutation	novel	T230K	0.06
BLCA	chr1	179587555	5'Flank	novel		0.12
BLCA	chr1	179652189	Missense_Mutation	rs563073215	R718C	0.33
BLCA	chr1	179669299	Missense_Mutation	NA	E865Q	0.12
BLCA	chr1	179635864	Silent	rs147568109	L499L	0.39
BLCA	chr1	179691083	3'UTR	novel		0.57
BLCA	chr1	179690942	Silent	novel	*982*	0.63
BLCA	chr1	179630904	Silent	NA	K370K	0.08
BLCA	chr1	179663378	Missense_Mutation	rs577467446	W792R	0.18
BLCA	chr1	179640443	Missense_Mutation	NA	E600Q	0.19
BRCA	chr1	179618627	Missense_Mutation	rs775805075	A287V	0.13
BRCA	chr1	179588303	5'Flank	novel		0.21
BRCA	chr1	179592602	Splice_Region	novel		0.14
BRCA	chr1	179663441	Missense_Mutation	NA	E813Q	0.15
BRCA	chr1	179592848	Splice_Site	novel	X78_splice	0.21
BRCA	chr1	179635807	Silent	NA	I480I	0.12
BRCA	chr1	179690755	Silent	NA	L920L	0.25
BRCA	chr1	179651037	Silent	novel	A657A	0.26
BRCA	chr1	179640379	Splice_Region	rs781235530	K578K	0.48
BRCA	chr1	179663372	Missense_Mutation	NA	D790N	0.29
BRCA	chr1	179618618	Missense_Mutation	NA	S284L	0.13
BRCA	chr1	179652177	Nonsense_Mutation	novel	E714*	0.05
BRCA	chr1	179630808	Missense_Mutation	NA	F338L	0.1
BRCA	chr1	179690846	Missense_Mutation	NA	R950Q	0.07
BRCA	chr1	179588301	5'Flank	novel		0.25
BRCA	chr1	179634577	Missense_Mutation	NA	P416L	0.18
CESC	chr1	179593659	Silent	rs369571297	A144A	0.42
CESC	chr1	179654284	Intron	novel		0.08
CESC	chr1	179593777	Missense_Mutation	NA	D184N	0.23
CESC	chr1	179588289	5'Flank	novel		0.39
CESC	chr1	179690812	Missense_Mutation	NA	E939Q	0.65
CESC	chr1	179592843	Silent	rs144528038	L76L	0.11
CESC	chr1	179587908	5'Flank	novel		0.52
CESC	chr1	179690858	Missense_Mutation	novel	T954I	0.11
CESC	chr1	179651019	Missense_Mutation	NA	L651F	0.46
CESC	chr1	179589044	5'Flank	novel		0.3
CESC	chr1	179650902	Missense_Mutation	novel	Q612H	0.39
CESC	chr1	179618652	Missense_Mutation	NA	I295M	0.43
CESC	chr1	179654276	Intron	novel		0.33
COAD	chr1	179662152	Missense_Mutation	NA	D737N	0.42
COAD	chr1	179588454	5'Flank	novel		0.31
COAD	chr1	179630843	Missense_Mutation	NA	D350V	0.09
COAD	chr1	179593679	Missense_Mutation	NA	S151Y	0.19
COAD	chr1	179650880	Missense_Mutation	NA	S605L	0.35
COAD	chr1	179634560	Frame_Shift_Del	NA	*K412Nfs17**	0.14
COAD	chr1	179639879	Missense_Mutation	novel	M521V	0.07
COAD	chr1	179650993	Missense_Mutation	NA	E643K	0.33
COAD	chr1	179592808	Missense_Mutation	rs375641517	R65C	0.39
COAD	chr1	179593770	Silent	rs755225162	A181A	0.51
COAD	chr1	179589035	5'Flank	novel		0.21
COAD	chr1	179587702	5'Flank	novel		0.15
COAD	chr1	179639954	Missense_Mutation	novel	I546V	0.33
COAD	chr1	179595807	Missense_Mutation	novel	K274Q	0.15
COAD	chr1	179630897	Missense_Mutation	rs113046765	A368V	0.09
COAD	chr1	179662125	Missense_Mutation	NA	P728T	0.15
COAD	chr1	179592767	Missense_Mutation	novel	R51Q	0.19
COAD	chr1	179592752	Missense_Mutation	rs775933425	R46Q	0.08	TUDOR
COAD	chr1	179595734	Silent	rs761083988	P249P	0.12
COAD	chr1	179639839	Splice_Region	novel	R507R	0.46
DLBC	chr1	179588445	5'Flank	novel		0.42
DLBC	chr1	179639991	Missense_Mutation	novel	V558G	0.15
ESCA	chr1	179669392	Missense_Mutation	novel	P896S	0.39
ESCA	chr1	179662153	Missense_Mutation	novel	D737A	0.14
ESCA	chr1	179690771	Missense_Mutation	rs570123255	R925H	0.21
ESCA	chr1	179621092	Splice_Site	rs746232955	X324_splice	0.15
ESCA	chr1	179650967	Frame_Shift_Del	NA	*L636Cfs16**	0.29
ESCA	chr1	179690799	Silent	rs371987660	L934L	0.2
ESCA	chr1	179662263	Missense_Mutation	novel	S774A	0.57
GBM	chr1	179690948	3'UTR	novel		0.35
GBM	chr1	179650964	Missense_Mutation	novel	N633S	0.47
GBM	chr1	179652090	Missense_Mutation	novel	P685S	0.4
GBM	chr1	179663405	Missense_Mutation	novel	L801I	0.04
GBM	chr1	179669222	Missense_Mutation	novel	S839Y	0.45
GBM	chr1	179652161	Missense_Mutation	novel	I708M	0.25
GBM	chr1	179593582	Missense_Mutation	rs748631957	R119W	0.51
GBM	chr1	179595790	Missense_Mutation	novel	R268I	0.05
GBM	chr1	179635679	Missense_Mutation	novel	N438Y	0.13
HNSC	chr1	179650981	Missense_Mutation	novel	T639A	0.24
HNSC	chr1	179640407	Missense_Mutation	novel	A588S	0.05
HNSC	chr1	179650967	Frame_Shift_Del	NA	*L636Cfs16**	0.46
HNSC	chr1	179640433	Silent	novel	V596V	0.1
HNSC	chr1	179618667	Silent	novel	K300K	0.24
HNSC	chr1	179593512	Silent	novel	R95R	0.23
HNSC	chr1	179650978	Missense_Mutation	novel	D638H	0.18
HNSC	chr1	179587665	5'Flank	novel		0.12
HNSC	chr1	179588686	5'Flank	novel		0.38
HNSC	chr1	179690780	Missense_Mutation	novel	S928C	0.22
HNSC	chr1	179592711	Missense_Mutation	novel	E32D	0.17	TUDOR
HNSC	chr1	179663405	Missense_Mutation	NA	L801F	0.24
HNSC	chr1	179592750	Silent	novel	L45L	0.21
HNSC	chr1	179634477	Nonsense_Mutation	novel	E383*	0.24
HNSC	chr1	179634620	Frame_Shift_Ins	novel	*L431Ifs20**	0.06
HNSC	chr1	179634621	In_Frame_Ins	novel	L431delinsCIFVKI	0.06
KIRC	chr1	179639895	Frame_Shift_Del	novel	*Q527Sfs8**	0.09
KIRP	chr1	179639907	Missense_Mutation	NA	H530P	0.17
LAML	chr1	179618667	Silent	novel	K300K	0.08
LGG	chr1	179593706	Missense_Mutation	novel	R160I	0.06
LGG	chr1	179663425	Frame_Shift_Ins	novel	*E808Hfs9**	0.1
LIHC	chr1	179669264	Missense_Mutation	novel	T853I	0.26
LIHC	chr1	179635834	Silent	NA	R489R	0.4
LIHC	chr1	179690748	Silent	NA	A917A	0.08
LIHC	chr1	179592796	Missense_Mutation	novel	P61S	0.1
LIHC	chr1	179662276	Missense_Mutation	novel	M778T	0.3
LIHC	chr1	179663440	Silent	rs147178825	P812P	0.31
LIHC	chr1	179662181	Silent	NA	P746P	0.58
LIHC	chr1	179640436	Silent	novel	R597R	0.29
LIHC	chr1	179630886	Silent	NA	L364L	0.36
LIHC	chr1	179592624	Silent	novel	E3E	0.39
LIHC	chr1	179634460	Missense_Mutation	NA	Q377L	0.04
LIHC	chr1	179595765	Nonsense_Mutation	novel	K260*	0.31
LIHC	chr1	179593652	Missense_Mutation	novel	L142Q	0.24
LIHC	chr1	179634460	Missense_Mutation	NA	Q377L	0.4
LIHC	chr1	179595787	Nonsense_Mutation	NA	S267*	0.17
LIHC	chr1	179654259	Intron	NA		0.09
LIHC	chr1	179630792	Frame_Shift_Ins	novel	*L336Ifs14**	0.11
LIHC	chr1	179592785	Missense_Mutation	novel	V57A	0.12
LIHC	chr1	179662195	Missense_Mutation	novel	M751T	0.31
LIHC	chr1	179640445	Missense_Mutation	novel	E600D	0.12
LIHC	chr1	179593575	Silent	novel	R116R	0.12
LIHC	chr1	179662104	Missense_Mutation	novel	D721N	0.15
LIHC	chr1	179593584	Silent	NA	R119R	0.34
LUAD	chr1	179669396	Missense_Mutation	rs779603364	S897F	0.14
LUAD	chr1	179634497	Silent	novel	S389S	0.08
LUAD	chr1	179662133	Silent	NA	L730L	0.08
LUAD	chr1	179592648	Silent	NA	L11L	0.35
LUAD	chr1	179650973	Nonsense_Mutation	novel	L636*	0.04
LUAD	chr1	179639842	Silent	novel	R508R	0.08
LUAD	chr1	179621036	Missense_Mutation	novel	V306A	0.36
LUAD	chr1	179635854	Nonsense_Mutation	novel	S496*	0.39
LUAD	chr1	179663480	Missense_Mutation	novel	R826G	0.48
LUAD	chr1	179588285	5'Flank	novel		0.15
LUAD	chr1	179588271	5'Flank	novel		0.63
LUAD	chr1	179592638	Missense_Mutation	novel	Q8P	0.32	TUDOR
LUAD	chr1	179588404	5'Flank	novel		0.24
LUAD	chr1	179634501	Missense_Mutation	novel	P391T	0.2
LUAD	chr1	179634502	Missense_Mutation	novel	P391Q	0.2
LUAD	chr1	179593550	Missense_Mutation	novel	R108I	0.55
LUAD	chr1	179662238	Silent	rs763691989	S765S	0.2
LUAD	chr1	179634477	Nonsense_Mutation	novel	E383*	0.21
LUAD	chr1	179618654	Missense_Mutation	NA	S296I	0.49
LUAD	chr1	179595804	Missense_Mutation	novel	E273K	0.23
LUAD	chr1	179592760	Missense_Mutation	novel	G49W	0.22	TUDOR
LUAD	chr1	179690861	Missense_Mutation	NA	A955V	0.1
LUAD	chr1	179690829	Missense_Mutation	novel	Q944H	0.27
LUAD	chr1	179650992	Missense_Mutation	NA	N642K	0.18
LUAD	chr1	179593545	Missense_Mutation	NA	K106N	0.21
LUAD	chr1	179690971	3'UTR	novel		0.27
LUAD	chr1	179690946	3'UTR	novel		0.2
LUAD	chr1	179593539	Missense_Mutation	novel	M104I	0.16
LUAD	chr1	179587674	5'Flank	novel		0.16
LUAD	chr1	179652171	Missense_Mutation	NA	S712P	0.15
LUAD	chr1	179690784	Silent	NA	V929V	0.35
LUAD	chr1	179618638	Missense_Mutation	NA	P291T	0.31
LUAD	chr1	179635677	Missense_Mutation	NA	T437K	0.24
LUAD	chr1	179662215	Missense_Mutation	novel	A758S	0.22
LUAD	chr1	179587665	5'Flank	novel		0.12
LUAD	chr1	179593800	Silent	NA	T191T	0.33
LUAD	chr1	179588366	5'Flank	novel		0.13
LUAD	chr1	179652111	Missense_Mutation	NA	E692K	0.17
LUSC	chr1	179650954	Missense_Mutation	novel	G630R	0.21
LUSC	chr1	179639922	Missense_Mutation	NA	R535K	0.34
LUSC	chr1	179639923	Silent	novel	R535R	0.34
LUSC	chr1	179595751	Missense_Mutation	novel	M255K	0.19
LUSC	chr1	179630815	Missense_Mutation	NA	V341L	0.35
LUSC	chr1	179651047	Nonsense_Mutation	rs768183823	R661*	0.07
LUSC	chr1	179639922	Missense_Mutation	NA	R535K	0.21
LUSC	chr1	179639923	Missense_Mutation	NA	R535S	0.21
LUSC	chr1	179662219	Frame_Shift_Del	novel	*H760Ifs43**	0.48
LUSC	chr1	179663486	Nonsense_Mutation	NA	Q828*	0.4
LUSC	chr1	179592808	Missense_Mutation	NA	R65S	0.29
LUSC	chr1	179588682	5'Flank	novel		0.4
LUSC	chr1	179663403	Missense_Mutation	novel	G800V	0.16
LUSC	chr1	179588686	5'Flank	novel		0.5
LUSC	chr1	179593568	Missense_Mutation	novel	G114A	0.28
LUSC	chr1	179635834	Silent	NA	R489R	0.1
LUSC	chr1	179662215	Missense_Mutation	rs145054790	A758T	0.25
LUSC	chr1	179630908	Missense_Mutation	novel	P372T	0.43
LUSC	chr1	179669388	Silent	novel	E894E	0.17
LUSC	chr1	179593864	Missense_Mutation	NA	A213P	0.43
LUSC	chr1	179690785	Missense_Mutation	NA	D930Y	0.15
LUSC	chr1	179593681	Missense_Mutation	novel	D152H	0.32
LUSC	chr1	179595684	Missense_Mutation	novel	P233T	0.16
LUSC	chr1	179690804	Nonsense_Mutation	NA	L936*	0.23
LUSC	chr1	179592635	Missense_Mutation	rs764470335	I7T	0.25	TUDOR
LUSC	chr1	179588701	5'Flank	novel		0.4
LUSC	chr1	179663352	Missense_Mutation	novel	W783L	0.27
LUSC	chr1	179595634	Missense_Mutation	novel	I216T	0.45
LUSC	chr1	179650930	Missense_Mutation	novel	G622W	0.1
LUSC	chr1	179592805	Missense_Mutation	NA	V64F	0.35
LUSC	chr1	179690918	Missense_Mutation	NA	P974H	0.38
LUSC	chr1	179635693	Silent	novel	L442L	0.07
LUSC	chr1	179663479	Missense_Mutation	novel	N825K	0.25
LUSC	chr1	179662171	Missense_Mutation	novel	N743S	0.23
LUSC	chr1	179639972	Missense_Mutation	NA	E552Q	0.45
LUSC	chr1	179639983	Missense_Mutation	NA	E555D	0.23
LUSC	chr1	179588567	5'Flank	novel		0.1
LUSC	chr1	179593672	Missense_Mutation	novel	L149V	0.12
LUSC	chr1	179652177	Missense_Mutation	novel	E714Q	0.3
OV	chr1	179690771	Missense_Mutation	rs570123255	R925H	0.18
OV	chr1	179690955	3'UTR	novel		0.15
OV	chr1	179592727	Missense_Mutation	novel	M38L	0.07	TUDOR
OV	chr1	179640046	Silent	NA	F576F	0.49
OV	chr1	179650951	Missense_Mutation	NA	D629N	0.16
PAAD	chr1	179635787	Missense_Mutation	novel	G474W	0.13
PAAD	chr1	179595644	Silent	novel	Q219Q	0.27
PAAD	chr1	179669402	Missense_Mutation	novel	S899Y	0.16
PRAD	chr1	179669208	Silent	NA	N834N	0.32
PRAD	chr1	179588369	5'Flank	novel		0.5
READ	chr1	179592751	Nonsense_Mutation	NA	R46*	0.3	TUDOR
READ	chr1	179634559	Frame_Shift_Ins	NA	*Q413Tfs13**	0.3
READ	chr1	179592620	Missense_Mutation	novel	S2Y	0.09
READ	chr1	179652064	Missense_Mutation	novel	A676V	0.42
READ	chr1	179635880	Nonsense_Mutation	novel	E505*	0.22
READ	chr1	179669248	Missense_Mutation	rs756995942	F848V	0.12
SARC	chr1	179669337	Missense_Mutation	novel	Q877H	0.09
SKCM	chr1	179635807	Silent	novel	I480I	0.16
SKCM	chr1	179662133	Silent	NA	L730L	0.29
SKCM	chr1	179593529	Missense_Mutation	NA	R101Q	0.13
SKCM	chr1	179635780	Silent	novel	S471S	0.42
SKCM	chr1	179588686	5'Flank	novel		0.36
SKCM	chr1	179635779	Missense_Mutation	NA	S471F	0.37
SKCM	chr1	179634614	Silent	NA	V428V	0.56
SKCM	chr1	179593855	Missense_Mutation	rs201086446	G210R	0.22
SKCM	chr1	179640036	Missense_Mutation	novel	S573F	0.44
SKCM	chr1	179640037	Silent	novel	S573S	0.45
SKCM	chr1	179595685	Missense_Mutation	rs756660429	P233L	0.38
SKCM	chr1	179663405	Missense_Mutation	NA	L801F	0.31
SKCM	chr1	179662164	Missense_Mutation	novel	D741N	0.21
SKCM	chr1	179662250	Silent	NA	K769K	0.25
SKCM	chr1	179690894	Missense_Mutation	NA	S966F	0.21
SKCM	chr1	179634587	Missense_Mutation	NA	K419N	0.27
SKCM	chr1	179650910	Missense_Mutation	NA	C615Y	0.16
SKCM	chr1	179635846	Silent	novel	R493R	0.15
SKCM	chr1	179651007	Silent	NA	F647F	0.1
SKCM	chr1	179669381	Missense_Mutation	NA	S892F	0.24
SKCM	chr1	179588695	5'Flank	novel		0.51
SKCM	chr1	179662198	Missense_Mutation	novel	G752E	0.49
SKCM	chr1	179593471	Missense_Mutation	NA	E82K	0.18
SKCM	chr1	179618645	Missense_Mutation	NA	G293E	0.29
SKCM	chr1	179634514	Missense_Mutation	NA	S395L	0.3
SKCM	chr1	179651007	Silent	NA	F647F	0.28
SKCM	chr1	179652057	Missense_Mutation	NA	P674S	0.08
SKCM	chr1	179690945	3'UTR	novel		0.73
SKCM	chr1	179640413	Missense_Mutation	novel	P590S	0.42
SKCM	chr1	179587602	5'Flank	novel		0.44
SKCM	chr1	179593715	Missense_Mutation	rs777146655	R163Q	0.35
SKCM	chr1	179618635	Missense_Mutation	novel	G290R	0.28
SKCM	chr1	179652074	Silent	rs779171277	T679T	0.24
SKCM	chr1	179588378	5'Flank	novel		0.19
SKCM	chr1	179662203	Missense_Mutation	NA	G754R	0.47
SKCM	chr1	179662152	Missense_Mutation	NA	D737N	0.46
SKCM	chr1	179662232	Silent	novel	T763T	0.16
SKCM	chr1	179691019	3'UTR	novel		0.26
SKCM	chr1	179635759	Silent	NA	L464L	0.52
SKCM	chr1	179595734	Silent	rs761083988	P249P	0.32
SKCM	chr1	179592715	Missense_Mutation	NA	E34K	0.56	TUDOR
SKCM	chr1	179662133	Silent	rs779027975	L730L	0.43
SKCM	chr1	179690715	Silent	NA	I906I	0.52
SKCM	chr1	179651026	Missense_Mutation	novel	E654K	0.21
SKCM	chr1	179618645	Missense_Mutation	NA	G293E	0.1
SKCM	chr1	179618645	Missense_Mutation	NA	G293E	0.19
SKCM	chr1	179589051	5'Flank	novel		0.14
SKCM	chr1	179650896	Silent	novel	Q610Q	0.11
SKCM	chr1	179663384	Missense_Mutation	NA	D794N	0.29
SKCM	chr1	179651007	Silent	NA	F647F	0.1
SKCM	chr1	179669250	Silent	novel	F848F	0.06
SKCM	chr1	179640018	Missense_Mutation	novel	G567E	0.38
SKCM	chr1	179634555	Missense_Mutation	NA	P409S	0.26
SKCM	chr1	179635851	Missense_Mutation	rs762569393	S495L	0.37
SKCM	chr1	179662142	Silent	novel	V733V	0.15
SKCM	chr1	179593802	Missense_Mutation	NA	R192K	0.08
SKCM	chr1	179662198	Missense_Mutation	novel	G752E	0.84
SKCM	chr1	179587381	5'Flank	novel		0.43
SKCM	chr1	179639870	Nonsense_Mutation	NA	R518*	0.36
SKCM	chr1	179690898	Silent	NA	R967R	0.21
SKCM	chr1	179690697	Splice_Region	rs760102745	V900V	0.23
SKCM	chr1	179630921	Splice_Site	NA	X376_splice	0.37
SKCM	chr1	179651058	Silent	NA	I664I	0.08
SKCM	chr1	179618647	Missense_Mutation	NA	T294A	0.23
SKCM	chr1	179618645	Missense_Mutation	NA	G293E	0.18
SKCM	chr1	179650942	Missense_Mutation	NA	E626K	0.27
SKCM	chr1	179669355	Silent	NA	P883P	0.08
SKCM	chr1	179587597	5'Flank	novel		0.44
SKCM	chr1	179587598	5'Flank	novel		0.44
SKCM	chr1	179663348	Missense_Mutation	NA	D782N	0.21
SKCM	chr1	179634600	Missense_Mutation	novel	P424T	0.14
SKCM	chr1	179634601	Missense_Mutation	novel	P424L	0.14
SKCM	chr1	179662163	Nonsense_Mutation	NA	W740*	0.35
SKCM	chr1	179595755	Missense_Mutation	NA	E256D	0.26
SKCM	chr1	179592757	Missense_Mutation	NA	L48F	0.4	TUDOR
SKCM	chr1	179662237	Missense_Mutation	NA	S765N	0.2
SKCM	chr1	179588591	5'Flank	novel		0.13
SKCM	chr1	179662130	Silent	NA	C729C	0.18
SKCM	chr1	179690964	3'UTR	novel		0.12
SKCM	chr1	179634459	Nonsense_Mutation	NA	Q377*	0.12
SKCM	chr1	179639870	Nonsense_Mutation	NA	R518*	0.11
SKCM	chr1	179588464	5'Flank	novel		0.15
SKCM	chr1	179592778	Missense_Mutation	novel	E55K	0.42
SKCM	chr1	179595652	Missense_Mutation	novel	R222K	0.45
SKCM	chr1	179630865	Silent	novel	R357R	0.22
SKCM	chr1	179595734	Silent	rs761083988	P249P	0.41
SKCM	chr1	179662155	Missense_Mutation	NA	D738N	0.17
SKCM	chr1	179618613	Silent	NA	F282F	0.18
SKCM	chr1	179690935	Missense_Mutation	novel	E980K	0.35
SKCM	chr1	179587696	5'Flank	novel		0.16
SKCM	chr1	179635876	Missense_Mutation	NA	M503I	0.08
SKCM	chr1	179587696	5'Flank	novel		0.35
SKCM	chr1	179592662	Missense_Mutation	NA	R16K	0.26	TUDOR
SKCM	chr1	179650993	Missense_Mutation	NA	E643K	0.45
SKCM	chr1	179639933	Missense_Mutation	novel	D539N	0.47
SKCM	chr1	179592730	Missense_Mutation	NA	V39I	0.1	TUDOR
SKCM	chr1	179650942	Missense_Mutation	NA	E626K	0.1
SKCM	chr1	179593529	Missense_Mutation	NA	R101Q	0.26
SKCM	chr1	179691045	3'UTR	novel		0.57
SKCM	chr1	179595780	Missense_Mutation	novel	E265K	0.25
SKCM	chr1	179650993	Missense_Mutation	NA	E643K	0.31
SKCM	chr1	179593843	Missense_Mutation	NA	E206K	0.25
SKCM	chr1	179663414	Missense_Mutation	NA	G804R	0.53
SKCM	chr1	179593586	Missense_Mutation	novel	R120Q	0.35
SKCM	chr1	179650881	Silent	rs150044249	S605S	0.43
SKCM	chr1	179650959	Silent	NA	I631I	0.61
SKCM	chr1	179593484	Missense_Mutation	novel	G86E	0.14
SKCM	chr1	179593843	Missense_Mutation	NA	E206K	0.17
SKCM	chr1	179662112	Silent	NA	I723I	0.35
SKCM	chr1	179690833	Missense_Mutation	NA	L946F	0.42
SKCM	chr1	179662155	Missense_Mutation	NA	D738N	0.42
SKCM	chr1	179662272	Missense_Mutation	novel	E777K	0.43
SKCM	chr1	179634575	Silent	novel	E415E	0.39
SKCM	chr1	179669382	Silent	rs780844485	S892S	0.45
STAD	chr1	179663419	Silent	rs149892600	T805T	0.31
STAD	chr1	179595782	Silent	NA	E265E	0.5
STAD	chr1	179587977	5'Flank	novel		0.54
STAD	chr1	179630793	Frame_Shift_Del	rs772423686	*K335Nfs2**	0.38
STAD	chr1	179690743	Missense_Mutation	rs530480530	R916C	0.35
STAD	chr1	179630871	Silent	NA	G359G	0.29
STAD	chr1	179650912	Missense_Mutation	rs199784694	G616S	0.36
STAD	chr1	179630881	Missense_Mutation	novel	L363I	0.22
STAD	chr1	179650967	Frame_Shift_Del	NA	*L636Cfs16**	0.14
STAD	chr1	179635787	Missense_Mutation	novel	G474R	0.05
STAD	chr1	179630792	Frame_Shift_Ins	novel	*L336Ifs14**	0.26
STAD	chr1	179592696	Silent	novel	S27S	0.05
STAD	chr1	179589054	5'Flank	novel		0.21
STAD	chr1	179662287	Splice_Site	NA	X781_splice	0.14
STAD	chr1	179588305	5'Flank	novel		0.17
STAD	chr1	179650911	Silent	rs762786138	C615C	0.19
THCA	chr1	179639918	Missense_Mutation	NA	V534I	0.44
THCA	chr1	179588282	5'Flank	novel		0.19
THYM	chr1	179691249	3'UTR	novel		0.12
UCEC	chr1	179630792	Frame_Shift_Ins	novel	*L336Ifs14**	0.5
UCEC	chr1	179634614	Silent	novel	V428V	0.07
UCEC	chr1	179635825	Missense_Mutation	NA	F486L	0.35
UCEC	chr1	179639911	Silent	NA	L531L	0.32
UCEC	chr1	179691211	3'UTR	novel		0.12
UCEC	chr1	179593473	Silent	rs576077105	E82E	0.3
UCEC	chr1	179690881	Missense_Mutation	NA	R962W	0.38
UCEC	chr1	179592808	Missense_Mutation	rs375641517	R65C	0.35
UCEC	chr1	179690932	Missense_Mutation	novel	M979V	0.52
UCEC	chr1	179691112	3'UTR	novel		0.09
UCEC	chr1	179592627	Missense_Mutation	NA	Q4H	0.31
UCEC	chr1	179639871	Missense_Mutation	rs367703698	R518Q	0.07
UCEC	chr1	179630772	Missense_Mutation	novel	I326M	0.37
UCEC	chr1	179650994	Missense_Mutation	novel	E643G	0.36
UCEC	chr1	179587398	5'Flank	novel		0.5
UCEC	chr1	179587357	5'Flank	novel		0.45
UCEC	chr1	179634559	Frame_Shift_Ins	NA	*Q413Tfs13**	0.39
UCEC	chr1	179634488	Silent	novel	A386A	0.25
UCEC	chr1	179618681	Missense_Mutation	novel	F305C	0.46
UCEC	chr1	179669383	Missense_Mutation	rs201146333	A893T	0.44
UCEC	chr1	179690742	Silent	rs754514262	S915S	0.58
UCEC	chr1	179593529	Missense_Mutation	NA	R101Q	0.28
UCEC	chr1	179593731	Missense_Mutation	novel	M168I	0.17
UCEC	chr1	179663481	Missense_Mutation	NA	R826M	0.24
UCEC	chr1	179592601	Splice_Site	novel		0.04
UCEC	chr1	179690964	3'UTR	novel		0.17
UCEC	chr1	179691226	3'UTR	novel		0.29
UCEC	chr1	179690875	Missense_Mutation	novel	A960T	0.43
UCEC	chr1	179588458	5'Flank	novel		0.46
UCEC	chr1	179639912	Missense_Mutation	novel	C532S	0.4
UCEC	chr1	179663375	Missense_Mutation	rs751674376	T791A	0.43
UCEC	chr1	179588366	5'Flank	novel		0.06
UCEC	chr1	179650966	Frame_Shift_Ins	novel	*L636Ffs3**	0.22
UCEC	chr1	179662187	Missense_Mutation	novel	Q748H	0.25
UCEC	chr1	179630877	Silent	novel	Q361Q	0.17
UCEC	chr1	179650955	Missense_Mutation	novel	G630E	0.3
UCEC	chr1	179690743	Missense_Mutation	rs530480530	R916C	0.3
UCEC	chr1	179593585	Nonsense_Mutation	novel	R120*	0.37
UCEC	chr1	179635865	Missense_Mutation	NA	E500K	0.46
UCEC	chr1	179654290	Intron	novel		0.1
UCEC	chr1	179593706	Missense_Mutation	novel	R160I	0.46
UCEC	chr1	179621036	Missense_Mutation	novel	V306D	0.53
UCEC	chr1	179691084	3'UTR	novel		0.47
UCEC	chr1	179592778	Missense_Mutation	novel	E55K	0.5
UCEC	chr1	179593658	Missense_Mutation	rs755169262	A144V	0.38
UCEC	chr1	179595634	Missense_Mutation	novel	I216N	0.25
UCEC	chr1	179690878	Missense_Mutation	rs757136807	A961T	0.52
UCEC	chr1	179593529	Missense_Mutation	NA	R101Q	0.46
UCEC	chr1	179663372	Missense_Mutation	novel	D790Y	0.41
UCEC	chr1	179654234	Intron	novel		0.3
UCEC	chr1	179662143	Missense_Mutation	novel	T734A	0.24
UCEC	chr1	179650928	Frame_Shift_Ins	novel	*V623Gfs4**	0.33
UCEC	chr1	179650967	Frame_Shift_Del	NA	*L636Cfs16**	0.18
UCEC	chr1	179592649	Missense_Mutation	rs201484897	R12W	0.11	TUDOR
UCEC	chr1	179588303	5'Flank	novel		0.26
UCEC	chr1	179618677	Missense_Mutation	novel	K304Q	0.29
UCEC	chr1	179663378	Missense_Mutation	rs577467446	W792R	0.39
UCEC	chr1	179650911	Silent	rs762786138	C615C	0.33
UCEC	chr1	179663491	Missense_Mutation	novel	K829N	0.36
UCEC	chr1	179593502	Frame_Shift_Ins	novel	*Q94Tfs6**	0.2
UCEC	chr1	179690770	Missense_Mutation	rs771332017	R925C	0.43
UCEC	chr1	179691060	3'UTR	novel		0.46
UCEC	chr1	179650966	Frame_Shift_Ins	novel	*L636Ffs3**	0.29
UCEC	chr1	179587696	5'Flank	novel		0.21
UCEC	chr1	179592711	Missense_Mutation	NA	E32D	0.25	TUDOR
UCEC	chr1	179621069	Missense_Mutation	NA	S317Y	0.24
UCEC	chr1	179651060	Missense_Mutation	NA	S665Y	0.17
UCEC	chr1	179663484	Missense_Mutation	rs750889576	T827I	0.06
UCEC	chr1	179690742	Silent	rs754514262	S915S	0.26
UCEC	chr1	179650890	Missense_Mutation	novel	I608M	0.13
UCEC	chr1	179650967	Frame_Shift_Del	NA	*L636Cfs16**	0.41
UCEC	chr1	179690865	Frame_Shift_Ins	novel	*L957Ffs43**	0.29
UCEC	chr1	179662220	Silent	novel	S759S	0.31
UCEC	chr1	179652167	Silent	NA	P710P	0.25
UCEC	chr1	179691211	3'UTR	novel		0.26
UCEC	chr1	179592673	Missense_Mutation	rs543279481	I20V	0.16	TUDOR
UCEC	chr1	179663459	Frame_Shift_Ins	novel	*N821Kfs45**	0.28
UCEC	chr1	179654341	Intron	rs760991160		0.08
UCEC	chr1	179663456	Nonsense_Mutation	NA	Q818*	0.49
UCEC	chr1	179593618	Missense_Mutation	novel	L131I	0.06
UCEC	chr1	179593582	Missense_Mutation	rs748631957	R119W	0.35
UCEC	chr1	179593706	Missense_Mutation	novel	R160I	0.38
UCEC	chr1	179593529	Missense_Mutation	NA	R101Q	0.23
UCEC	chr1	179593744	Missense_Mutation	novel	L173F	0.49
UCEC	chr1	179635737	Missense_Mutation	rs750726121	P457L	0.34
UCEC	chr1	179635833	Missense_Mutation	rs772079229	R489Q	0.16
UCEC	chr1	179639842	Silent	novel	R508R	0.42
UCEC	chr1	179652153	Nonsense_Mutation	novel	R706*	0.16
UCEC	chr1	179690846	Missense_Mutation	NA	R950Q	0.54
UCEC	chr1	179691210	3'UTR	novel		0.29
UCEC	chr1	179588601	5'Flank	novel		0.14
UCEC	chr1	179595700	Missense_Mutation	novel	C238F	0.08
UCEC	chr1	179650880	Missense_Mutation	NA	S605L	0.16
UCEC	chr1	179662151	Silent	NA	G736G	0.14
UCEC	chr1	179593766	Missense_Mutation	NA	N180S	0.11
UCEC	chr1	179588681	5'Flank	novel		0.09
UCEC	chr1	179593675	Missense_Mutation	novel	L150I	0.39
UCEC	chr1	179635831	Silent	NA	I488I	0.57
UCEC	chr1	179654280	Intron	novel		0.29
UCEC	chr1	179691053	3'UTR	novel		0.36
UCEC	chr1	179593550	Missense_Mutation	novel	R108I	0.39
UCS	chr1	179595634	Missense_Mutation	novel	I216N	0.21
UCS	chr1	179630795	Missense_Mutation	novel	K334T	0.32
UVM	chr1	179587388	5'Flank	novel		0.57

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.0208	0.0017831
KIRC	AMP	0.0909	0.059566
PAAD	AMP	0.2283	0.085665
TGCT	AMP	0.3467	0.088103
THCA	AMP	0.0501	0.075436

Survival Analysis

Cancer	P-value	Q-value
THYM	0.037	Kaplan-Meier Survival Analysis
KIRC	0.016	Kaplan-Meier Survival Analysis
MESO	0.043	Kaplan-Meier Survival Analysis
HNSC	0.014	Kaplan-Meier Survival Analysis
KICH	0.022	Kaplan-Meier Survival Analysis
UCEC	0.0002	Kaplan-Meier Survival Analysis
LIHC	0.00055	Kaplan-Meier Survival Analysis
LGG	0.0074	Kaplan-Meier Survival Analysis