EuRBPDB

Description

Ensembl ID: ENSG00000162923 (Gene tree)
Gene ID: 80232
Gene Symbol: WDR26
Alias: FLJ21016|GID7
Full Name: WD repeat domain 26
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 51,891 bases
Position: chr1:224,385,143-224,437,033
Accession: 21208
RBP type: canonical RBP
Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000424784	eIF2A	PF08662.11	2.6e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000489825	WDR26-209	751	-	-	- (aa)	-	-
ENST00000477425	WDR26-204	529	-	-	- (aa)	-	-
ENST00000479727	WDR26-205	795	-	-	- (aa)	-	-
ENST00000479778	WDR26-206	2552	-	-	- (aa)	-	-
ENST00000486652	WDR26-208	2867	-	ENSP00000422758	208 (aa)	-	H0Y917
ENST00000414423	WDR26-201	7367	XM_005273273	ENSP00000408108	661 (aa)	XP_005273330	Q9H7D7
ENST00000443112	WDR26-202	1306	-	-	- (aa)	-	-
ENST00000445239	WDR26-203	784	-	ENSP00000403597	125 (aa)	-	C9JCS7
ENST00000480676	WDR26-207	1725	XM_011544282	ENSP00000424784	295 (aa)	XP_011542584	H0Y9R3

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000162923	rs34687215	1	224394506	C	White blood cell count	27863252	[0.017-0.034] unit increase	0.02575367	EFO_0004308
ENSG00000162923	rs6675269	1	224412564	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000162923	rs2897048	1	224423205	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000162923	rs28434172	1	224426923	?	White blood cell count	30595370			EFO_0004308

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000162923	WDR26	99	98.299	ENSAPLG00000013139	WDR26	100	95.429	Anas_platyrhynchos
ENSG00000162923	WDR26	100	100.000	ENSDORG00000005340	Wdr26	98	97.168	Dipodomys_ordii
ENSG00000162923	WDR26	99	98.299	ENSFALG00000011769	WDR26	99	92.933	Ficedula_albicollis
ENSG00000162923	WDR26	99	97.635	ENSGALG00000043081	WDR26	96	98.202	Gallus_gallus
ENSG00000162923	WDR26	86	97.628	ENSMGAG00000008239	WDR26	100	92.464	Meleagris_gallopavo
ENSG00000162923	WDR26	97	90.909	ENSMALG00000011021	-	78	89.231	Monopterus_albus
ENSG00000162923	WDR26	100	100.000	ENSPTIG00000014132	WDR26	96	98.066	Panthera_tigris_altaica
ENSG00000162923	WDR26	99	98.980	ENSPSIG00000007716	WDR26	100	95.525	Pelodiscus_sinensis
ENSG00000162923	WDR26	100	99.200	ENSSHAG00000007205	WDR26	100	98.651	Sarcophilus_harrisii
ENSG00000162923	WDR26	99	97.959	ENSTGUG00000004059	WDR26	100	96.196	Taeniopygia_guttata
ENSG00000162923	WDR26	100	100.000	ENSVPAG00000012522	WDR26	100	99.805	Vicugna_pacos

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000151	ubiquitin ligase complex	29911972.	IDA	Component
GO:0005515	protein binding	17510365.27098453.	IPI	Function
GO:0005634	nucleus	29911972.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	15378603.	IDA	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component