EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000163002 (Gene tree)
Gene ID: 129401
Gene Symbol: NUP35
Alias: MP44
Full Name: nucleoporin 35
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 44,195 bases
Position: chr2:183,117,490-183,161,684
Accession: 29797
RBP type: canonical RBP
Summary: This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000387305	Nup35_RRM	PF05172.13	9.2e-26	1	1
ENSP00000295119	Nup35_RRM	PF05172.13	1e-25	1	1
ENSP00000387305	Nup35_RRM_2	PF14605.6	2.6e-09	1	1
ENSP00000295119	Nup35_RRM_2	PF14605.6	2.8e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000409798	NUP35-203	1470	XM_006712254	ENSP00000387305	309 (aa)	XP_006712317	Q8NFH5
ENST00000374930	NUP35-202	998	-	ENSP00000364066	152 (aa)	-	F8WEL4
ENST00000446612	NUP35-205	470	-	ENSP00000412554	115 (aa)	-	C9IYQ7
ENST00000455063	NUP35-207	342	-	ENSP00000393130	53 (aa)	-	C9JWU7
ENST00000452137	NUP35-206	755	-	ENSP00000412311	136 (aa)	-	F8WCF5
ENST00000497330	NUP35-210	544	-	-	- (aa)	-	-
ENST00000472844	NUP35-208	514	-	-	- (aa)	-	-
ENST00000295119	NUP35-201	1633	-	ENSP00000295119	326 (aa)	-	Q8NFH5
ENST00000479162	NUP35-209	2828	-	-	- (aa)	-	-
ENST00000442895	NUP35-204	616	-	ENSP00000403819	76 (aa)	-	C9JIY9

Gene Model

Click here to download ENSG00000163002's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000163002	Myocardial Infarction	3.5133654E-004	-
ENSG00000163002	Myocardial Infarction	9.1052245E-004	-
ENSG00000163002	Body Height	6.9900000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000163002's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000163002	NUP35	100	63.750	ENSAPOG00000003630	nup35	99	61.635	Acanthochromis_polyacanthus
ENSG00000163002	NUP35	100	98.684	ENSAMEG00000001191	NUP35	100	96.049	Ailuropoda_melanoleuca
ENSG00000163002	NUP35	83	61.390	ENSACIG00000023984	nup35	98	61.390	Amphilophus_citrinellus
ENSG00000163002	NUP35	100	65.000	ENSAOCG00000007484	nup35	99	62.264	Amphiprion_ocellaris
ENSG00000163002	NUP35	100	65.000	ENSAPEG00000020027	nup35	99	62.461	Amphiprion_percula
ENSG00000163002	NUP35	100	67.105	ENSATEG00000019305	nup35	99	62.540	Anabas_testudineus
ENSG00000163002	NUP35	100	89.474	ENSAPLG00000009161	NUP35	99	84.568	Anas_platyrhynchos
ENSG00000163002	NUP35	100	80.968	ENSACAG00000008692	NUP35	100	79.331	Anolis_carolinensis
ENSG00000163002	NUP35	100	100.000	ENSANAG00000021090	NUP35	100	98.160	Aotus_nancymaae
ENSG00000163002	NUP35	100	65.823	ENSACLG00000013918	nup35	99	60.366	Astatotilapia_calliptera
ENSG00000163002	NUP35	100	82.895	ENSAMXG00000003371	nup35	100	76.375	Astyanax_mexicanus
ENSG00000163002	NUP35	100	97.368	ENSBTAG00000009777	NUP35	100	96.330	Bos_taurus
ENSG00000163002	NUP35	100	100.000	ENSCJAG00000011104	NUP35	100	99.080	Callithrix_jacchus
ENSG00000163002	NUP35	100	100.000	ENSCAFG00000031849	NUP35	100	97.115	Canis_familiaris
ENSG00000163002	NUP35	100	100.000	ENSCAFG00020008408	NUP35	100	96.353	Canis_lupus_dingo
ENSG00000163002	NUP35	100	98.684	ENSCHIG00000023148	NUP35	100	97.419	Capra_hircus
ENSG00000163002	NUP35	100	98.684	ENSTSYG00000002117	NUP35	100	94.785	Carlito_syrichta
ENSG00000163002	NUP35	100	96.226	ENSCAPG00000005703	NUP35	100	78.723	Cavia_aperea
ENSG00000163002	NUP35	100	97.368	ENSCPOG00000011906	NUP35	100	95.107	Cavia_porcellus
ENSG00000163002	NUP35	100	100.000	ENSCCAG00000025009	NUP35	100	99.080	Cebus_capucinus
ENSG00000163002	NUP35	100	100.000	ENSCATG00000033109	NUP35	100	84.969	Cercocebus_atys
ENSG00000163002	NUP35	100	96.226	ENSCLAG00000012559	NUP35	100	93.884	Chinchilla_lanigera
ENSG00000163002	NUP35	100	100.000	ENSCSAG00000012620	NUP35	100	99.693	Chlorocebus_sabaeus
ENSG00000163002	NUP35	100	90.789	ENSCPBG00000001303	NUP35	100	86.850	Chrysemys_picta_bellii
ENSG00000163002	NUP35	99	41.538	ENSCING00000009659	-	97	41.896	Ciona_intestinalis
ENSG00000163002	NUP35	99	43.109	ENSCSAVG00000007467	-	99	43.478	Ciona_savignyi
ENSG00000163002	NUP35	100	100.000	ENSCANG00000030785	NUP35	100	99.693	Colobus_angolensis_palliatus
ENSG00000163002	NUP35	100	97.368	ENSCGRG00001018638	-	100	95.399	Cricetulus_griseus_chok1gshd
ENSG00000163002	NUP35	100	97.368	ENSCGRG00000011313	-	100	95.399	Cricetulus_griseus_crigri
ENSG00000163002	NUP35	100	62.025	ENSCSEG00000000938	nup35	99	58.934	Cynoglossus_semilaevis
ENSG00000163002	NUP35	100	66.667	ENSCVAG00000001792	nup35	99	62.145	Cyprinodon_variegatus
ENSG00000163002	NUP35	100	81.579	ENSDARG00000012222	nup35	100	74.434	Danio_rerio
ENSG00000163002	NUP35	100	97.368	ENSDNOG00000009513	-	88	94.801	Dasypus_novemcinctus
ENSG00000163002	NUP35	100	97.368	ENSDNOG00000038754	-	100	94.190	Dasypus_novemcinctus
ENSG00000163002	NUP35	100	98.684	ENSDORG00000010458	-	100	94.785	Dipodomys_ordii
ENSG00000163002	NUP35	100	97.368	ENSETEG00000005896	NUP35	100	95.208	Echinops_telfairi
ENSG00000163002	NUP35	99	61.333	ENSEBUG00000013034	nup35	99	52.778	Eptatretus_burgeri
ENSG00000163002	NUP35	100	98.684	ENSEASG00005022100	NUP35	100	96.024	Equus_asinus_asinus
ENSG00000163002	NUP35	100	98.684	ENSECAG00000003968	NUP35	100	96.774	Equus_caballus
ENSG00000163002	NUP35	100	96.053	ENSEEUG00000008469	NUP35	100	86.544	Erinaceus_europaeus
ENSG00000163002	NUP35	100	82.895	ENSELUG00000013693	nup35	100	75.161	Esox_lucius
ENSG00000163002	NUP35	100	98.684	ENSFCAG00000025636	NUP35	100	95.833	Felis_catus
ENSG00000163002	NUP35	100	86.842	ENSFALG00000013175	NUP35	100	82.622	Ficedula_albicollis
ENSG00000163002	NUP35	100	97.368	ENSFDAG00000017998	NUP35	100	93.558	Fukomys_damarensis
ENSG00000163002	NUP35	100	69.231	ENSFHEG00000010229	nup35	99	62.461	Fundulus_heteroclitus
ENSG00000163002	NUP35	83	55.469	ENSGMOG00000003337	nup35	100	55.469	Gadus_morhua
ENSG00000163002	NUP35	100	86.842	ENSGALG00000002689	NUP35	100	82.875	Gallus_gallus
ENSG00000163002	NUP35	100	65.000	ENSGAFG00000022048	nup35	99	61.755	Gambusia_affinis
ENSG00000163002	NUP35	100	65.385	ENSGACG00000008203	nup35	99	60.635	Gasterosteus_aculeatus
ENSG00000163002	NUP35	100	90.789	ENSGAGG00000001967	NUP35	100	88.746	Gopherus_agassizii
ENSG00000163002	NUP35	100	100.000	ENSGGOG00000009919	NUP35	100	100.000	Gorilla_gorilla
ENSG00000163002	NUP35	100	86.842	ENSHGLG00000008616	-	96	78.095	Heterocephalus_glaber_female
ENSG00000163002	NUP35	100	94.839	ENSHGLG00000013230	NUP35	100	94.190	Heterocephalus_glaber_female
ENSG00000163002	NUP35	100	86.842	ENSHGLG00000000414	-	97	74.841	Heterocephalus_glaber_female
ENSG00000163002	NUP35	100	86.842	ENSHGLG00100010869	-	97	74.841	Heterocephalus_glaber_male
ENSG00000163002	NUP35	100	94.839	ENSHGLG00100012840	NUP35	100	94.190	Heterocephalus_glaber_male
ENSG00000163002	NUP35	100	86.842	ENSHGLG00100000091	-	96	78.095	Heterocephalus_glaber_male
ENSG00000163002	NUP35	100	66.667	ENSHCOG00000003882	nup35	99	58.861	Hippocampus_comes
ENSG00000163002	NUP35	100	71.053	ENSIPUG00000002798	nup35	100	67.791	Ictalurus_punctatus
ENSG00000163002	NUP35	100	95.793	ENSSTOG00000000711	NUP35	100	95.399	Ictidomys_tridecemlineatus
ENSG00000163002	NUP35	100	97.368	ENSJJAG00000016432	-	100	94.172	Jaculus_jaculus
ENSG00000163002	NUP35	100	84.906	ENSJJAG00000007003	-	98	79.141	Jaculus_jaculus
ENSG00000163002	NUP35	93	92.958	ENSJJAG00000006387	-	93	88.087	Jaculus_jaculus
ENSG00000163002	NUP35	100	96.226	ENSJJAG00000017434	-	99	86.646	Jaculus_jaculus
ENSG00000163002	NUP35	100	61.728	ENSKMAG00000011162	nup35	98	61.250	Kryptolebias_marmoratus
ENSG00000163002	NUP35	100	70.513	ENSLBEG00000012416	nup35	99	49.216	Labrus_bergylta
ENSG00000163002	NUP35	100	81.818	ENSLACG00000008247	NUP35	100	79.421	Latimeria_chalumnae
ENSG00000163002	NUP35	100	78.947	ENSLOCG00000006726	nup35	99	71.656	Lepisosteus_oculatus
ENSG00000163002	NUP35	100	98.113	ENSLAFG00000008155	NUP35	100	93.072	Loxodonta_africana
ENSG00000163002	NUP35	100	100.000	ENSMFAG00000000834	NUP35	100	99.387	Macaca_fascicularis
ENSG00000163002	NUP35	100	100.000	ENSMMUG00000004140	NUP35	100	99.693	Macaca_mulatta
ENSG00000163002	NUP35	100	100.000	ENSMNEG00000029014	NUP35	100	99.693	Macaca_nemestrina
ENSG00000163002	NUP35	100	100.000	ENSMLEG00000035422	NUP35	100	99.693	Mandrillus_leucophaeus
ENSG00000163002	NUP35	100	64.935	ENSMAMG00000013232	nup35	99	59.502	Mastacembelus_armatus
ENSG00000163002	NUP35	100	67.089	ENSMZEG00005020619	nup35	95	61.300	Maylandia_zebra
ENSG00000163002	NUP35	100	84.211	ENSMGAG00000004412	NUP35	100	80.428	Meleagris_gallopavo
ENSG00000163002	NUP35	100	98.684	ENSMAUG00000013776	-	100	95.399	Mesocricetus_auratus
ENSG00000163002	NUP35	100	98.684	ENSMICG00000006790	NUP35	100	96.774	Microcebus_murinus
ENSG00000163002	NUP35	100	98.113	ENSMOCG00000014754	-	100	94.172	Microtus_ochrogaster
ENSG00000163002	NUP35	100	63.750	ENSMMOG00000005026	nup35	99	59.177	Mola_mola
ENSG00000163002	NUP35	100	93.421	ENSMODG00000010578	NUP35	100	89.297	Monodelphis_domestica
ENSG00000163002	NUP35	100	65.000	ENSMALG00000020187	nup35	99	60.815	Monopterus_albus
ENSG00000163002	NUP35	100	98.684	MGP_CAROLIEiJ_G0023709	-	100	93.252	Mus_caroli
ENSG00000163002	NUP35	100	97.368	ENSMUSG00000026999	Nup35	100	92.945	Mus_musculus
ENSG00000163002	NUP35	100	98.684	MGP_PahariEiJ_G0025160	-	100	93.865	Mus_pahari
ENSG00000163002	NUP35	86	81.000	MGP_SPRETEiJ_G0033063	-	100	81.000	Mus_spretus
ENSG00000163002	NUP35	100	100.000	ENSMPUG00000002063	NUP35	100	96.657	Mustela_putorius_furo
ENSG00000163002	NUP35	100	98.684	ENSMLUG00000013154	NUP35	100	95.719	Myotis_lucifugus
ENSG00000163002	NUP35	100	97.368	ENSNGAG00000012107	-	100	94.172	Nannospalax_galili
ENSG00000163002	NUP35	100	62.500	ENSNBRG00000020466	nup35	99	60.061	Neolamprologus_brichardi
ENSG00000163002	NUP35	100	100.000	ENSNLEG00000035026	NUP35	100	100.000	Nomascus_leucogenys
ENSG00000163002	NUP35	69	68.224	ENSMEUG00000003001	-	65	68.224	Notamacropus_eugenii
ENSG00000163002	NUP35	83	94.922	ENSOPRG00000016609	NUP35	78	94.922	Ochotona_princeps
ENSG00000163002	NUP35	100	73.276	ENSODEG00000000280	-	99	69.538	Octodon_degus
ENSG00000163002	NUP35	100	97.368	ENSODEG00000011202	-	100	94.801	Octodon_degus
ENSG00000163002	NUP35	100	62.963	ENSONIG00000016251	nup35	99	58.841	Oreochromis_niloticus
ENSG00000163002	NUP35	100	89.474	ENSOANG00000006793	-	97	87.288	Ornithorhynchus_anatinus
ENSG00000163002	NUP35	100	98.684	ENSOCUG00000014407	NUP35	100	95.706	Oryctolagus_cuniculus
ENSG00000163002	NUP35	100	66.250	ENSORLG00000013588	nup35	100	61.905	Oryzias_latipes
ENSG00000163002	NUP35	100	66.250	ENSORLG00020008201	nup35	99	61.875	Oryzias_latipes_hni
ENSG00000163002	NUP35	100	66.250	ENSORLG00015011096	nup35	100	61.587	Oryzias_latipes_hsok
ENSG00000163002	NUP35	100	65.000	ENSOMEG00000007628	nup35	99	60.188	Oryzias_melastigma
ENSG00000163002	NUP35	100	96.226	ENSOGAG00000011920	NUP35	100	95.107	Otolemur_garnettii
ENSG00000163002	NUP35	100	98.684	ENSOARG00000016728	NUP35	100	96.942	Ovis_aries
ENSG00000163002	NUP35	100	100.000	ENSPPAG00000036316	NUP35	100	100.000	Pan_paniscus
ENSG00000163002	NUP35	100	98.684	ENSPPRG00000024726	NUP35	100	96.154	Panthera_pardus
ENSG00000163002	NUP35	100	98.684	ENSPTIG00000017299	NUP35	100	95.441	Panthera_tigris_altaica
ENSG00000163002	NUP35	100	100.000	ENSPTRG00000012711	NUP35	100	100.000	Pan_troglodytes
ENSG00000163002	NUP35	100	100.000	ENSPANG00000013686	NUP35	100	99.693	Papio_anubis
ENSG00000163002	NUP35	100	80.263	ENSPKIG00000022051	nup35	99	75.321	Paramormyrops_kingsleyae
ENSG00000163002	NUP35	100	89.474	ENSPSIG00000002146	NUP35	100	86.774	Pelodiscus_sinensis
ENSG00000163002	NUP35	100	64.557	ENSPMGG00000022915	nup35	97	58.176	Periophthalmus_magnuspinnatus
ENSG00000163002	NUP35	100	98.684	ENSPEMG00000014718	-	100	96.012	Peromyscus_maniculatus_bairdii
ENSG00000163002	NUP35	100	63.158	ENSPMAG00000006604	nup35	96	57.764	Petromyzon_marinus
ENSG00000163002	NUP35	100	96.226	ENSPCIG00000015482	NUP35	100	91.437	Phascolarctos_cinereus
ENSG00000163002	NUP35	100	65.000	ENSPFOG00000010020	nup35	99	61.442	Poecilia_formosa
ENSG00000163002	NUP35	100	65.000	ENSPLAG00000005867	nup35	99	61.129	Poecilia_latipinna
ENSG00000163002	NUP35	100	67.949	ENSPMEG00000010552	nup35	99	62.461	Poecilia_mexicana
ENSG00000163002	NUP35	100	68.421	ENSPREG00000021005	nup35	99	62.222	Poecilia_reticulata
ENSG00000163002	NUP35	100	100.000	ENSPPYG00000012998	-	80	99.693	Pongo_abelii
ENSG00000163002	NUP35	100	96.226	ENSPCAG00000000605	NUP35	96	65.495	Procavia_capensis
ENSG00000163002	NUP35	100	98.684	ENSPCOG00000024097	NUP35	100	96.636	Propithecus_coquereli
ENSG00000163002	NUP35	100	98.684	ENSPVAG00000015908	NUP35	100	95.719	Pteropus_vampyrus
ENSG00000163002	NUP35	100	65.854	ENSPNYG00000012486	nup35	95	61.610	Pundamilia_nyererei
ENSG00000163002	NUP35	100	82.895	ENSPNAG00000005181	nup35	98	76.508	Pygocentrus_nattereri
ENSG00000163002	NUP35	100	98.684	ENSRNOG00000009290	Nup35	100	94.479	Rattus_norvegicus
ENSG00000163002	NUP35	100	100.000	ENSRBIG00000039427	NUP35	100	99.693	Rhinopithecus_bieti
ENSG00000163002	NUP35	100	100.000	ENSRROG00000026525	NUP35	100	99.387	Rhinopithecus_roxellana
ENSG00000163002	NUP35	100	99.130	ENSSBOG00000018676	NUP35	100	98.773	Saimiri_boliviensis_boliviensis
ENSG00000163002	NUP35	100	93.421	ENSSHAG00000009746	NUP35	100	91.131	Sarcophilus_harrisii
ENSG00000163002	NUP35	100	80.263	ENSSFOG00015002390	nup35	99	75.159	Scleropages_formosus
ENSG00000163002	NUP35	100	65.789	ENSSMAG00000015651	nup35	99	60.127	Scophthalmus_maximus
ENSG00000163002	NUP35	100	66.667	ENSSDUG00000013118	nup35	99	59.190	Seriola_dumerili
ENSG00000163002	NUP35	100	66.667	ENSSLDG00000018249	nup35	99	60.443	Seriola_lalandi_dorsalis
ENSG00000163002	NUP35	100	94.340	ENSSARG00000001535	-	100	70.513	Sorex_araneus
ENSG00000163002	NUP35	100	85.526	ENSSPUG00000018651	NUP35	100	82.569	Sphenodon_punctatus
ENSG00000163002	NUP35	100	69.231	ENSSPAG00000018264	nup35	99	61.875	Stegastes_partitus
ENSG00000163002	NUP35	100	100.000	ENSSSCG00000028949	NUP35	100	96.330	Sus_scrofa
ENSG00000163002	NUP35	100	82.895	ENSTGUG00000011278	NUP35	100	80.851	Taeniopygia_guttata
ENSG00000163002	NUP35	100	61.250	ENSTRUG00000014111	nup35	99	57.288	Takifugu_rubripes
ENSG00000163002	NUP35	100	52.104	ENSTNIG00000011568	nup35	95	52.548	Tetraodon_nigroviridis
ENSG00000163002	NUP35	100	100.000	ENSTBEG00000003328	NUP35	100	92.661	Tupaia_belangeri
ENSG00000163002	NUP35	100	100.000	ENSTTRG00000002512	NUP35	100	82.569	Tursiops_truncatus
ENSG00000163002	NUP35	64	96.447	ENSUAMG00000018696	-	96	96.447	Ursus_americanus
ENSG00000163002	NUP35	100	100.000	ENSUMAG00000017104	NUP35	100	96.078	Ursus_maritimus
ENSG00000163002	NUP35	100	100.000	ENSVPAG00000011898	NUP35	100	96.636	Vicugna_pacos
ENSG00000163002	NUP35	100	100.000	ENSVVUG00000016832	NUP35	100	96.795	Vulpes_vulpes
ENSG00000163002	NUP35	100	80.263	ENSXETG00000001335	nup35	100	66.061	Xenopus_tropicalis
ENSG00000163002	NUP35	100	66.250	ENSXMAG00000000409	nup35	99	61.755	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003697	single-stranded DNA binding	21873635.	IBA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005543	phospholipid binding	21873635.	IBA	Function
GO:0005635	nuclear envelope	-	TAS	Component
GO:0005652	nuclear lamina	-	IEA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0006110	regulation of glycolytic process	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006409	tRNA export from nucleus	-	TAS	Process
GO:0006607	NLS-bearing protein import into nucleus	21873635.	IBA	Process
GO:0006999	nuclear pore organization	21873635.	IBA	Process
GO:0016032	viral process	-	TAS	Process
GO:0016925	protein sumoylation	-	TAS	Process
GO:0017056	structural constituent of nuclear pore	21873635.	IBA	Function
GO:0019083	viral transcription	-	TAS	Process
GO:0031965	nuclear membrane	-	IDA	Component
GO:0043657	host cell	-	IEA	Component
GO:0044613	nuclear pore central transport channel	21873635.	IBA	Component
GO:0044615	nuclear pore nuclear basket	21873635.	IBA	Component
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process
GO:0075733	intracellular transport of virus	-	TAS	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process