EuRBPDB

Description

Ensembl ID: ENSG00000163166 (Gene tree)
Gene ID: 55677
Gene Symbol: IWS1
Alias: DKFZp761G0123|FLJ10006|FLJ14655|FLJ32319
Full Name: interacts with SUPT6H, CTD assembly factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 90,680 bases
Position: chr2:127,436,207-127,526,886
Accession: 25467
RBP type: non-canonical RBP
Summary: (Interacts With SUPT6H, CTD Assembly Factor 1) is a Protein Coding gene. Among its related pathways are Tat-mediated elongation of the HIV-1 transcript and Gene Expression. An important paralog of this gene is MDN1.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000479083	IWS1-207	582	-	-	- (aa)	-	-
ENST00000295321	IWS1-201	2958	XM_005263707	ENSP00000295321	819 (aa)	XP_005263764	Q96ST2
ENST00000495369	IWS1-210	811	-	-	- (aa)	-	-
ENST00000436740	IWS1-204	608	-	-	- (aa)	-	-
ENST00000486662	IWS1-209	870	-	-	- (aa)	-	-
ENST00000478949	IWS1-206	567	-	-	- (aa)	-	-
ENST00000637187	IWS1-212	1021	-	ENSP00000490836	207 (aa)	-	A0A1B0GW95
ENST00000497888	IWS1-211	592	-	-	- (aa)	-	-
ENST00000460511	IWS1-205	598	-	-	- (aa)	-	-
ENST00000409725	IWS1-202	1080	-	ENSP00000387206	292 (aa)	-	B8ZZB6
ENST00000412979	IWS1-203	441	-	ENSP00000396710	33 (aa)	-	H7C0U1
ENST00000483889	IWS1-208	588	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000163166	Basophils	2.5660000E-005	-
ENSG00000163166	Education	9E-6	25201988

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000163166	rs334147	2	127498481	T	Educational attainment	25201988	[NR] unit decrease	0.046	EFO_0004784

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	17234882.19141475.25689719.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	17234882.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0010793	regulation of mRNA export from nucleus	21873635.	IBA	Process
GO:0010793	regulation of mRNA export from nucleus	17234882.	IMP	Process
GO:0050684	regulation of mRNA processing	21873635.	IBA	Process
GO:0050684	regulation of mRNA processing	17234882.	IMP	Process
GO:0051028	mRNA transport	-	IEA	Process
GO:0090239	regulation of histone H4 acetylation	19141475.	IMP	Process
GO:2001253	regulation of histone H3-K36 trimethylation	21873635.	IBA	Process
GO:2001253	regulation of histone H3-K36 trimethylation	19141475.	IMP	Process