EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000163539 (Gene tree)
Gene ID: 23122
Gene Symbol: CLASP2
Alias: KIAA0627
Full Name: cytoplasmic linker associated protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 222,112 bases
Position: chr3:33,496,245-33,718,356
Accession: 17078
RBP type: non-canonical RBP
Summary: (Cytoplasmic Linker Associated Protein 2) is a Protein Coding gene. Diseases associated with CLASP2 include Clostridium Difficile Colitis. Among its related pathways are Developmental Biology and Signaling by Robo receptor. Gene Ontology (GO) annotations related to this gene include binding and microtubule plus-end binding. An important paralog of this gene is CLASP1.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000480385	CLASP2-214	614	-	ENSP00000417386	205 (aa)	-	H7C4I5
ENST00000485378	CLASP2-216	874	-	ENSP00000418945	233 (aa)	-	D6RBU8
ENST00000482896	CLASP2-215	580	-	-	- (aa)	-	-
ENST00000464961	CLASP2-207	6273	-	-	- (aa)	-	-
ENST00000480013	CLASP2-213	5972	XM_017005970	ENSP00000417518	1293 (aa)	XP_016861459	J3KR49
ENST00000493577	CLASP2-221	875	-	-	- (aa)	-	-
ENST00000498331	CLASP2-224	452	-	-	- (aa)	-	-
ENST00000462878	CLASP2-206	892	-	-	- (aa)	-	-
ENST00000486796	CLASP2-217	656	-	-	- (aa)	-	-
ENST00000496954	CLASP2-223	685	-	ENSP00000418411	178 (aa)	-	C9J668
ENST00000487200	CLASP2-218	1940	-	ENSP00000418939	454 (aa)	-	B3KR06
ENST00000491045	CLASP2-220	558	-	-	- (aa)	-	-
ENST00000475576	CLASP2-210	536	-	ENSP00000417666	178 (aa)	-	H7C4M5
ENST00000399362	CLASP2-204	7282	XM_006713041	ENSP00000382297	1513 (aa)	XP_006713104	E7ERI8
ENST00000487553	CLASP2-219	825	-	ENSP00000420307	220 (aa)	-	H7C5M8
ENST00000313350	CLASP2-201	1597	-	ENSP00000324364	431 (aa)	-	O75122
ENST00000635664	CLASP2-225	4176	XM_017005968	ENSP00000489023	1304 (aa)	XP_016861457	A0A0U1RQI6
ENST00000333778	CLASP2-202	1989	-	ENSP00000327760	458 (aa)	-	E7ENG2
ENST00000468888	CLASP2-209	6978	XM_006713040	ENSP00000419974	1514 (aa)	XP_006713103	E7EW49
ENST00000461133	CLASP2-205	4814	XM_017005972	ENSP00000419305	1273 (aa)	XP_016861461	E3W994
ENST00000476433	CLASP2-212	574	-	-	- (aa)	-	-
ENST00000476251	CLASP2-211	1097	-	ENSP00000418488	184 (aa)	-	H7C4X8
ENST00000467956	CLASP2-208	485	-	-	- (aa)	-	-
ENST00000494261	CLASP2-222	764	-	-	- (aa)	-	-
ENST00000359576	CLASP2-203	7141	-	ENSP00000352581	1515 (aa)	-	O75122

Gene Model

Click here to download ENSG00000163539's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000163539	Behcet Syndrome	2.7003368211439E-05	20622878

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000163539's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000163539	CLASP2	100	98.876	ENSMUSG00000033392	Clasp2	100	97.425	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000226	microtubule cytoskeleton organization	24859005.26003921.	IMP	Process
GO:0000776	kinetochore	16866869.	IMP	Component
GO:0000777	condensed chromosome kinetochore	-	IEA	Component
GO:0002162	dystroglycan binding	23940118.	IPI	Function
GO:0005515	protein binding	11290329.17543864.19632184.26496610.27173435.	IPI	Function
GO:0005737	cytoplasm	11290329.	NAS	Component
GO:0005794	Golgi apparatus	11290329.	IDA	Component
GO:0005802	trans-Golgi network	17543864.	IDA	Component
GO:0005815	microtubule organizing center	-	IEA	Component
GO:0005828	kinetochore microtubule	12837247.	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005874	microtubule	17543864.20937854.	IDA	Component
GO:0005874	microtubule	24859005.	IDA	Component
GO:0005881	cytoplasmic microtubule	11290329.	IDA	Component
GO:0005886	plasma membrane	20937854.	IDA	Component
GO:0005925	focal adhesion	24859005.	IDA	Component
GO:0005938	cell cortex	17113391.	IDA	Component
GO:0006903	vesicle targeting	24859005.	IMP	Process
GO:0007020	microtubule nucleation	17543864.	IMP	Process
GO:0007026	negative regulation of microtubule depolymerization	11290329.	NAS	Process
GO:0007030	Golgi organization	24859005.	IMP	Process
GO:0007052	mitotic spindle organization	16866869.	IMP	Process
GO:0007163	establishment or maintenance of cell polarity	15928712.	TAS	Process
GO:0008017	microtubule binding	26003921.	IDA	Function
GO:0010458	exit from mitosis	16866869.	IMP	Process
GO:0010470	regulation of gastrulation	23940118.	IMP	Process
GO:0010634	positive regulation of epithelial cell migration	24859005.	IMP	Process
GO:0010717	regulation of epithelial to mesenchymal transition	23940118.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0031023	microtubule organizing center organization	17543864.	IMP	Process
GO:0031110	regulation of microtubule polymerization or depolymerization	11290329.	IMP	Process
GO:0031252	cell leading edge	24859005.	IDA	Component
GO:0032587	ruffle membrane	20937854.	IDA	Component
GO:0032886	regulation of microtubule-based process	20937854.	IMP	Process
GO:0034453	microtubule anchoring	17543864.24859005.	IMP	Process
GO:0045180	basal cortex	23940118.	IDA	Component
GO:0045921	positive regulation of exocytosis	24859005.	IMP	Process
GO:0051010	microtubule plus-end binding	11290329.19632184.	IDA	Function
GO:0051301	cell division	-	IEA	Process
GO:0051497	negative regulation of stress fiber assembly	24859005.	IMP	Process
GO:0051895	negative regulation of focal adhesion assembly	24859005.	IMP	Process
GO:0072659	protein localization to plasma membrane	23940118.	IMP	Process
GO:0072686	mitotic spindle	16866869.	IMP	Component
GO:0090091	positive regulation of extracellular matrix disassembly	24859005.	IMP	Process
GO:1903690	negative regulation of wound healing, spreading of epidermal cells	24859005.	IMP	Process
GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	23940118.	IMP	Process