EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000163798 (Gene tree)
Gene ID: 22950
Gene Symbol: SLC4A1AP
Alias: kanadaptin|HLC3
Full Name: solute carrier family 4 member 1 adaptor protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 31,510 bases
Position: chr2:27,663,471-27,694,980
Accession: 13813
RBP type: canonical RBP
Summary: (Solute Carrier Family 4 Member 1 Adaptor Protein) is a Protein Coding gene. An important paralog of this gene is PPP1R8.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000480182	dsrm	PF00035.26	0.0003	1	1
ENSP00000483501	dsrm	PF00035.26	0.0005	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000613517	SLC4A1AP-205	819	-	ENSP00000480182	273 (aa)	-	A0A087WWF4
ENST00000613058	SLC4A1AP-204	2966	-	ENSP00000479964	796 (aa)	-	Q9BWU0
ENST00000326019	SLC4A1AP-201	2959	-	ENSP00000323837	796 (aa)	-	Q9BWU0
ENST00000618046	SLC4A1AP-206	2544	-	ENSP00000483501	742 (aa)	-	A0A087X0M4
ENST00000492196	SLC4A1AP-203	2537	-	-	- (aa)	-	-
ENST00000427424	SLC4A1AP-202	906	-	ENSP00000404129	157 (aa)	-	H7C256

Gene Model

Click here to download ENSG00000163798's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000163798	Alzheimer Disease	2E-6	22159054

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000163798	rs17006206	2	27684606	G	Alzheimer's disease	22159054	[1.52-2.76]	2.05	EFO_0000249

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000163798's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000163798	SLC4A1AP	100	94.323	ENSBTAG00000018680	-	100	82.062	Bos_taurus
ENSG00000163798	SLC4A1AP	91	40.667	WBGene00014011	ZK632.2	72	36.116	Caenorhabditis_elegans
ENSG00000163798	SLC4A1AP	100	98.253	ENSCJAG00000009108	SLC4A1AP	100	93.935	Callithrix_jacchus
ENSG00000163798	SLC4A1AP	100	95.197	ENSCHIG00000013579	SLC4A1AP	100	82.685	Capra_hircus
ENSG00000163798	SLC4A1AP	84	94.760	ENSTSYG00000009786	SLC4A1AP	98	86.130	Carlito_syrichta
ENSG00000163798	SLC4A1AP	65	96.067	ENSCAPG00000016780	-	85	88.140	Cavia_aperea
ENSG00000163798	SLC4A1AP	100	81.452	ENSCPOG00000004368	SLC4A1AP	100	80.780	Cavia_porcellus
ENSG00000163798	SLC4A1AP	100	98.253	ENSCCAG00000028455	SLC4A1AP	100	93.396	Cebus_capucinus
ENSG00000163798	SLC4A1AP	100	99.127	ENSCATG00000036961	SLC4A1AP	100	97.439	Cercocebus_atys
ENSG00000163798	SLC4A1AP	100	98.690	ENSCSAG00000010252	SLC4A1AP	100	96.496	Chlorocebus_sabaeus
ENSG00000163798	SLC4A1AP	91	74.825	ENSCPBG00000025393	SLC4A1AP	90	59.521	Chrysemys_picta_bellii
ENSG00000163798	SLC4A1AP	100	93.886	ENSCGRG00001007282	Slc4a1ap	100	78.841	Cricetulus_griseus_chok1gshd
ENSG00000163798	SLC4A1AP	100	93.886	ENSCGRG00000003453	Slc4a1ap	100	78.841	Cricetulus_griseus_crigri
ENSG00000163798	SLC4A1AP	100	96.070	ENSEASG00005009074	SLC4A1AP	100	85.849	Equus_asinus_asinus
ENSG00000163798	SLC4A1AP	100	96.070	ENSECAG00000024129	SLC4A1AP	100	85.175	Equus_caballus
ENSG00000163798	SLC4A1AP	91	73.427	ENSGAGG00000007785	SLC4A1AP	99	58.910	Gopherus_agassizii
ENSG00000163798	SLC4A1AP	100	99.127	ENSMFAG00000034281	SLC4A1AP	100	97.170	Macaca_fascicularis
ENSG00000163798	SLC4A1AP	100	99.127	ENSMMUG00000019748	SLC4A1AP	100	97.170	Macaca_mulatta
ENSG00000163798	SLC4A1AP	100	99.127	ENSMNEG00000044853	SLC4A1AP	100	96.900	Macaca_nemestrina
ENSG00000163798	SLC4A1AP	100	98.690	ENSMLEG00000044084	SLC4A1AP	100	97.170	Mandrillus_leucophaeus
ENSG00000163798	SLC4A1AP	100	92.576	ENSMAUG00000004372	Slc4a1ap	100	85.989	Mesocricetus_auratus
ENSG00000163798	SLC4A1AP	100	95.197	ENSMICG00000014967	SLC4A1AP	100	87.634	Microcebus_murinus
ENSG00000163798	SLC4A1AP	100	91.739	MGP_CAROLIEiJ_G0027097	Slc4a1ap	100	82.617	Mus_caroli
ENSG00000163798	SLC4A1AP	100	92.174	MGP_PahariEiJ_G0029284	Slc4a1ap	100	82.243	Mus_pahari
ENSG00000163798	SLC4A1AP	100	94.323	ENSMPUG00000017992	SLC4A1AP	100	83.962	Mustela_putorius_furo
ENSG00000163798	SLC4A1AP	100	99.127	ENSNLEG00000004025	SLC4A1AP	100	97.844	Nomascus_leucogenys
ENSG00000163798	SLC4A1AP	89	84.286	ENSMEUG00000015128	-	81	91.304	Notamacropus_eugenii
ENSG00000163798	SLC4A1AP	71	82.883	ENSODEG00000007242	SLC4A1AP	100	67.871	Octodon_degus
ENSG00000163798	SLC4A1AP	84	82.969	ENSOANG00000005683	-	99	69.598	Ornithorhynchus_anatinus
ENSG00000163798	SLC4A1AP	65	80.337	ENSPSIG00000004013	SLC4A1AP	97	60.852	Pelodiscus_sinensis
ENSG00000163798	SLC4A1AP	91	100.000	ENSPPYG00000029403	-	100	98.305	Pongo_abelii
ENSG00000163798	SLC4A1AP	99	92.982	ENSRNOG00000004901	Slc4a1ap	100	77.524	Rattus_norvegicus
ENSG00000163798	SLC4A1AP	100	99.127	ENSRBIG00000043949	SLC4A1AP	100	97.170	Rhinopithecus_bieti
ENSG00000163798	SLC4A1AP	100	99.127	ENSRROG00000045303	SLC4A1AP	100	97.170	Rhinopithecus_roxellana
ENSG00000163798	SLC4A1AP	100	96.943	ENSSBOG00000021692	SLC4A1AP	100	93.531	Saimiri_boliviensis_boliviensis
ENSG00000163798	SLC4A1AP	89	82.857	ENSSHAG00000014807	SLC4A1AP	100	71.076	Sarcophilus_harrisii
ENSG00000163798	SLC4A1AP	84	75.966	ENSSPUG00000006128	-	85	63.766	Sphenodon_punctatus
ENSG00000163798	SLC4A1AP	100	95.633	ENSSSCG00000008549	SLC4A1AP	99	84.173	Sus_scrofa
ENSG00000163798	SLC4A1AP	91	88.811	ENSUAMG00000012393	SLC4A1AP	100	74.059	Ursus_americanus
ENSG00000163798	SLC4A1AP	84	89.083	ENSVPAG00000003376	SLC4A1AP	100	84.390	Vicugna_pacos
ENSG00000163798	SLC4A1AP	60	98.171	ENSVVUG00000001847	SLC4A1AP	98	88.621	Vulpes_vulpes
ENSG00000163798	SLC4A1AP	84	72.489	ENSXETG00000022503	slc4a1ap	75	67.206	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0005515	protein binding	17553790.25416956.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component