EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000163874 (Gene tree)
Gene ID: 80149
Gene Symbol: ZC3H12A
Alias: FLJ23231|MCPIP1
Full Name: zinc finger CCCH-type containing 12A
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,925 bases
Position: chr1:37,473,455-37,484,379
Accession: 26259
RBP type: canonical RBP
Summary: ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000362179	RNase_Zc3h12a	PF11977.8	1.1e-64	1	1
ENSP00000473447	RNase_Zc3h12a	PF11977.8	1.8e-16	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
26833120	MCPIP1 Selectively Destabilizes Transcripts Associated with an Antiapoptotic Gene Expression Program in Breast Cancer Cells That Can Elicit Complete Tumor Regression.	Cancer Res	2016 Mar 15	Lu W	doi: 10.1158/0008-5472.CAN-15-1115
30590418	MCPIP1 mediates inflammatory responses induced by lipopolysaccharide and lipoteichoic acid in bovine mammary epithelial cells.	Acta Biochim Biophys Sin (Shanghai)	2019 Feb 1	Qi S	doi: 10.1093/abbs/gmy163.
30655309	UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond.	RNA	2019 Apr	Kim YK	doi: 10.1261/rna.070136.118
31236273	Post-transcriptional control of immune responses and its potential application.	Clin Transl Immunology	2019 Jun 17	Yoshinaga M	doi: 10.1002/cti2.1063
28929622	Endonuclease Regnase-1/Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) in controlling immune responses and beyond.	Wiley Interdiscip Rev RNA	2018 Jan	Takeuchi O	doi: 10.1002/wrna.1449
23355615	MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation.	Nucleic Acids Res	2013 Mar 1	Lin RJ	doi: 10.1093/nar/gkt019
22132693	Post-transcriptional regulation of IL-6 production by Zc3h12a in fibroblast-like synovial cells.	Clin Exp Rheumatol	2011 Nov-Dec	Koga T	-
25225661	MCPIP1 suppresses hepatitis C virus replication and negatively regulates virus-induced proinflammatory cytokine responses.	J Immunol	2014 Oct 15	Lin RJ	doi: 10.4049/jimmunol.1400337
28155712	Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs.	BMC Genomics	2016 Dec 22	Kumagai Y	doi: 10.1186/s12864-016-3325-7.
26871597	Regulation of T cell signaling and autoimmunity by RNA-binding proteins.	Curr Opin Immunol	2016 Apr	Jeltsch KM	doi: 10.1016/j.coi.2016.01.011
26000482	Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms.	Cell	2015 May 21	Mino T	doi: 10.1016/j.cell.2015.04.029.
29043433	MCPIP1 inhibits coxsackievirus B3 replication by targeting viral RNA and negatively regulates virus-induced inflammation.	Med Microbiol Immunol	2018 Feb	Li M	doi: 10.1007/s00430-017-0523-0
29127149	Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis.	J Immunol	2017 Dec 15	Cui X	doi: 10.4049/jimmunol.1701211
29471506	A translational silencing function of MCPIP1/Regnase-1 specified by the target site context.	Nucleic Acids Res	2018 May 4	Behrens G	doi: 10.1093/nar/gky106.
22561375	Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase.	Nucleic Acids Res	2012 Aug	Xu J	doi: 10.1093/nar/gks359
25282160	Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.	Nat Immunol	2014 Nov	Jeltsch KM	doi: 10.1038/ni.3008
29743536	Substrate specificity of human MCPIP1 endoribonuclease.	Sci Rep	2018 May 9	Wilamowski M	doi: 10.1038/s41598-018-25765-2.
31099043	MCPIP1 alleviated lipopolysaccharide-induced liver injury by regulating SIRT1 via modulation of microRNA-9.	J Cell Physiol	2019 May 16	Han S	doi: 10.1002/jcp.28809

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471012	ZC3H12A-202	395	-	ENSP00000473447	131 (aa)	-	R4GN17
ENST00000472312	ZC3H12A-203	593	-	-	- (aa)	-	-
ENST00000640233	ZC3H12A-204	2721	-	ENSP00000492053	283 (aa)	-	A0A1W2PQC8
ENST00000373087	ZC3H12A-201	2684	XM_011542198	ENSP00000362179	599 (aa)	XP_011540500	Q5D1E8

Gene Model

Click here to download ENSG00000163874's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000163874's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000163874	ZC3H12A	84	56.000	ENSG00000178199	ZC3H12D	97	72.816

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000163874	ZC3H12A	82	64.435	ENSAPOG00000024328	zc3h12a	50	61.791	Acanthochromis_polyacanthus
ENSG00000163874	ZC3H12A	89	55.512	ENSAPOG00000005848	-	53	59.190	Acanthochromis_polyacanthus
ENSG00000163874	ZC3H12A	86	63.265	ENSAPOG00000001632	-	75	65.931	Acanthochromis_polyacanthus
ENSG00000163874	ZC3H12A	99	86.364	ENSAMEG00000000991	ZC3H12A	99	86.364	Ailuropoda_melanoleuca
ENSG00000163874	ZC3H12A	84	61.943	ENSACIG00000004135	si:dkey-206d17.12	83	63.710	Amphilophus_citrinellus
ENSG00000163874	ZC3H12A	86	56.967	ENSACIG00000006790	-	94	47.742	Amphilophus_citrinellus
ENSG00000163874	ZC3H12A	81	64.315	ENSACIG00000017750	zc3h12a	51	64.486	Amphilophus_citrinellus
ENSG00000163874	ZC3H12A	95	56.679	ENSAOCG00000003866	-	99	55.636	Amphiprion_ocellaris
ENSG00000163874	ZC3H12A	80	63.404	ENSAOCG00000001288	-	92	60.800	Amphiprion_ocellaris
ENSG00000163874	ZC3H12A	84	57.741	ENSAOCG00000009106	-	51	61.111	Amphiprion_ocellaris
ENSG00000163874	ZC3H12A	95	60.148	ENSAOCG00000014326	-	97	59.774	Amphiprion_ocellaris
ENSG00000163874	ZC3H12A	80	63.404	ENSAPEG00000022263	-	92	60.800	Amphiprion_percula
ENSG00000163874	ZC3H12A	85	60.081	ENSAPEG00000005727	-	97	49.383	Amphiprion_percula
ENSG00000163874	ZC3H12A	95	60.148	ENSAPEG00000021795	si:dkey-206d17.12	97	59.774	Amphiprion_percula
ENSG00000163874	ZC3H12A	89	55.512	ENSAPEG00000004229	-	53	59.190	Amphiprion_percula
ENSG00000163874	ZC3H12A	82	67.647	ENSATEG00000009946	zc3h12a	67	55.841	Anabas_testudineus
ENSG00000163874	ZC3H12A	78	61.435	ENSATEG00000013053	-	79	59.912	Anabas_testudineus
ENSG00000163874	ZC3H12A	80	67.094	ENSATEG00000006140	si:dkey-206d17.12	85	56.494	Anabas_testudineus
ENSG00000163874	ZC3H12A	96	55.986	ENSATEG00000002260	-	100	55.477	Anabas_testudineus
ENSG00000163874	ZC3H12A	80	70.667	ENSACAG00000017285	ZC3H12A	92	55.272	Anolis_carolinensis
ENSG00000163874	ZC3H12A	100	95.053	ENSANAG00000009908	ZC3H12A	100	95.053	Aotus_nancymaae
ENSG00000163874	ZC3H12A	80	65.812	ENSACLG00000004488	si:dkey-206d17.12	90	44.481	Astatotilapia_calliptera
ENSG00000163874	ZC3H12A	86	58.197	ENSACLG00000018534	-	51	61.093	Astatotilapia_calliptera
ENSG00000163874	ZC3H12A	81	68.376	ENSAMXG00000001736	zc3h12a	66	69.481	Astyanax_mexicanus
ENSG00000163874	ZC3H12A	84	65.432	ENSAMXG00000029641	si:dkey-206d17.12	79	65.844	Astyanax_mexicanus
ENSG00000163874	ZC3H12A	80	57.872	ENSAMXG00000030754	-	54	60.197	Astyanax_mexicanus
ENSG00000163874	ZC3H12A	97	86.792	ENSBTAG00000011316	ZC3H12A	100	86.792	Bos_taurus
ENSG00000163874	ZC3H12A	100	93.155	ENSCJAG00000041792	ZC3H12A	100	93.322	Callithrix_jacchus
ENSG00000163874	ZC3H12A	97	81.880	ENSCAFG00000003304	ZC3H12A	100	81.880	Canis_familiaris
ENSG00000163874	ZC3H12A	97	81.880	ENSCAFG00020008620	ZC3H12A	100	81.880	Canis_lupus_dingo
ENSG00000163874	ZC3H12A	99	86.242	ENSCHIG00000021957	ZC3H12A	100	86.621	Capra_hircus
ENSG00000163874	ZC3H12A	100	89.482	ENSTSYG00000035959	ZC3H12A	100	89.482	Carlito_syrichta
ENSG00000163874	ZC3H12A	92	86.775	ENSCAPG00000015365	ZC3H12A	99	86.885	Cavia_aperea
ENSG00000163874	ZC3H12A	92	86.775	ENSCPOG00000011081	ZC3H12A	99	86.885	Cavia_porcellus
ENSG00000163874	ZC3H12A	100	93.990	ENSCCAG00000023848	ZC3H12A	100	94.157	Cebus_capucinus
ENSG00000163874	ZC3H12A	100	97.005	ENSCATG00000037700	ZC3H12A	100	97.005	Cercocebus_atys
ENSG00000163874	ZC3H12A	96	89.781	ENSCLAG00000008722	ZC3H12A	99	85.260	Chinchilla_lanigera
ENSG00000163874	ZC3H12A	100	96.339	ENSCSAG00000001106	ZC3H12A	100	96.339	Chlorocebus_sabaeus
ENSG00000163874	ZC3H12A	81	81.739	ENSCPBG00000018492	ZC3H12A	94	56.894	Chrysemys_picta_bellii
ENSG00000163874	ZC3H12A	100	97.005	ENSCANG00000042287	ZC3H12A	100	97.005	Colobus_angolensis_palliatus
ENSG00000163874	ZC3H12A	96	87.546	ENSCGRG00001015497	Zc3h12a	100	81.302	Cricetulus_griseus_chok1gshd
ENSG00000163874	ZC3H12A	96	87.546	ENSCGRG00000013149	Zc3h12a	100	81.302	Cricetulus_griseus_crigri
ENSG00000163874	ZC3H12A	90	58.052	ENSCSEG00000019043	zc3h12a	99	44.175	Cynoglossus_semilaevis
ENSG00000163874	ZC3H12A	84	60.729	ENSCSEG00000010073	-	99	53.691	Cynoglossus_semilaevis
ENSG00000163874	ZC3H12A	80	63.675	ENSCSEG00000010348	si:dkey-206d17.12	61	55.474	Cynoglossus_semilaevis
ENSG00000163874	ZC3H12A	90	59.846	ENSCVAG00000016808	-	100	59.231	Cyprinodon_variegatus
ENSG00000163874	ZC3H12A	94	54.710	ENSCVAG00000001077	-	98	55.720	Cyprinodon_variegatus
ENSG00000163874	ZC3H12A	80	68.261	ENSCVAG00000001516	si:dkey-206d17.12	92	47.140	Cyprinodon_variegatus
ENSG00000163874	ZC3H12A	82	66.942	ENSCVAG00000017420	zc3h12a	66	54.460	Cyprinodon_variegatus
ENSG00000163874	ZC3H12A	80	67.949	ENSDARG00000101034	si:dkey-206d17.12	90	47.651	Danio_rerio
ENSG00000163874	ZC3H12A	83	67.797	ENSDARG00000005271	zc3h12a	83	69.381	Danio_rerio
ENSG00000163874	ZC3H12A	99	84.615	ENSDNOG00000035006	ZC3H12A	99	85.067	Dasypus_novemcinctus
ENSG00000163874	ZC3H12A	96	85.036	ENSDORG00000012666	Zc3h12a	99	81.650	Dipodomys_ordii
ENSG00000163874	ZC3H12A	96	68.248	ENSETEG00000018311	ZC3H12A	100	73.482	Echinops_telfairi
ENSG00000163874	ZC3H12A	97	88.336	ENSEASG00005012220	ZC3H12A	100	88.336	Equus_asinus_asinus
ENSG00000163874	ZC3H12A	97	88.448	ENSECAG00000009562	ZC3H12A	94	88.448	Equus_caballus
ENSG00000163874	ZC3H12A	87	81.766	ENSEEUG00000005907	ZC3H12A	100	81.766	Erinaceus_europaeus
ENSG00000163874	ZC3H12A	91	57.529	ENSELUG00000009319	-	53	59.942	Esox_lucius
ENSG00000163874	ZC3H12A	80	65.532	ENSELUG00000018274	zc3h12a	70	56.563	Esox_lucius
ENSG00000163874	ZC3H12A	79	64.935	ENSELUG00000007368	si:dkey-206d17.12	75	53.810	Esox_lucius
ENSG00000163874	ZC3H12A	99	86.700	ENSFCAG00000008757	ZC3H12A	99	86.700	Felis_catus
ENSG00000163874	ZC3H12A	84	76.151	ENSFALG00000000890	ZC3H12A	97	56.551	Ficedula_albicollis
ENSG00000163874	ZC3H12A	100	84.000	ENSFDAG00000006446	ZC3H12A	100	84.000	Fukomys_damarensis
ENSG00000163874	ZC3H12A	80	64.957	ENSFHEG00000001174	si:dkey-206d17.12	94	45.363	Fundulus_heteroclitus
ENSG00000163874	ZC3H12A	80	59.664	ENSFHEG00000021225	-	83	47.826	Fundulus_heteroclitus
ENSG00000163874	ZC3H12A	78	58.079	ENSFHEG00000011425	-	53	61.224	Fundulus_heteroclitus
ENSG00000163874	ZC3H12A	82	65.532	ENSFHEG00000001019	zc3h12a	66	66.450	Fundulus_heteroclitus
ENSG00000163874	ZC3H12A	79	63.755	ENSGMOG00000007388	-	99	46.609	Gadus_morhua
ENSG00000163874	ZC3H12A	78	64.602	ENSGMOG00000017603	si:dkey-206d17.12	81	54.237	Gadus_morhua
ENSG00000163874	ZC3H12A	50	75.229	ENSGMOG00000017975	-	50	82.292	Gadus_morhua
ENSG00000163874	ZC3H12A	82	78.879	ENSGALG00000002021	ZC3H12A	89	56.452	Gallus_gallus
ENSG00000163874	ZC3H12A	78	62.174	ENSGAFG00000019001	si:dkey-206d17.12	50	65.480	Gambusia_affinis
ENSG00000163874	ZC3H12A	78	60.987	ENSGAFG00000009523	-	53	62.329	Gambusia_affinis
ENSG00000163874	ZC3H12A	79	63.362	ENSGACG00000002341	si:dkey-206d17.12	97	47.803	Gasterosteus_aculeatus
ENSG00000163874	ZC3H12A	80	58.952	ENSGACG00000006636	-	91	59.000	Gasterosteus_aculeatus
ENSG00000163874	ZC3H12A	83	67.083	ENSGACG00000013859	zc3h12a	99	48.103	Gasterosteus_aculeatus
ENSG00000163874	ZC3H12A	86	76.923	ENSGAGG00000003881	ZC3H12A	94	56.338	Gopherus_agassizii
ENSG00000163874	ZC3H12A	100	99.332	ENSGGOG00000009268	ZC3H12A	100	99.332	Gorilla_gorilla
ENSG00000163874	ZC3H12A	89	58.268	ENSHBUG00000021584	-	99	57.463	Haplochromis_burtoni
ENSG00000163874	ZC3H12A	82	65.690	ENSHBUG00000009356	zc3h12a	66	55.035	Haplochromis_burtoni
ENSG00000163874	ZC3H12A	80	65.385	ENSHBUG00000017076	si:dkey-206d17.12	90	43.987	Haplochromis_burtoni
ENSG00000163874	ZC3H12A	96	87.226	ENSHGLG00000012808	ZC3H12A	100	83.167	Heterocephalus_glaber_female
ENSG00000163874	ZC3H12A	96	87.226	ENSHGLG00100002244	ZC3H12A	100	82.667	Heterocephalus_glaber_male
ENSG00000163874	ZC3H12A	52	48.980	ENSHCOG00000007306	-	85	47.973	Hippocampus_comes
ENSG00000163874	ZC3H12A	80	62.832	ENSHCOG00000008878	-	58	50.641	Hippocampus_comes
ENSG00000163874	ZC3H12A	89	55.469	ENSHCOG00000004255	si:dkey-206d17.12	98	54.980	Hippocampus_comes
ENSG00000163874	ZC3H12A	80	68.831	ENSIPUG00000015158	Zc3h12a	57	71.667	Ictalurus_punctatus
ENSG00000163874	ZC3H12A	82	65.957	ENSIPUG00000005852	si:dkey-206d17.12	90	45.455	Ictalurus_punctatus
ENSG00000163874	ZC3H12A	79	60.714	ENSIPUG00000011663	-	53	62.799	Ictalurus_punctatus
ENSG00000163874	ZC3H12A	100	86.477	ENSSTOG00000026842	ZC3H12A	100	86.477	Ictidomys_tridecemlineatus
ENSG00000163874	ZC3H12A	96	88.278	ENSJJAG00000004252	Zc3h12a	100	83.973	Jaculus_jaculus
ENSG00000163874	ZC3H12A	79	61.161	ENSKMAG00000014401	-	55	61.695	Kryptolebias_marmoratus
ENSG00000163874	ZC3H12A	80	67.699	ENSKMAG00000002156	ZC3H12A	84	67.841	Kryptolebias_marmoratus
ENSG00000163874	ZC3H12A	79	63.362	ENSKMAG00000013285	-	86	64.783	Kryptolebias_marmoratus
ENSG00000163874	ZC3H12A	80	62.083	ENSLBEG00000012554	-	85	50.955	Labrus_bergylta
ENSG00000163874	ZC3H12A	78	53.540	ENSLBEG00000012121	-	90	42.581	Labrus_bergylta
ENSG00000163874	ZC3H12A	80	61.803	ENSLBEG00000017593	si:dkey-206d17.12	97	44.231	Labrus_bergylta
ENSG00000163874	ZC3H12A	82	68.376	ENSLBEG00000027429	zc3h12a	66	55.478	Labrus_bergylta
ENSG00000163874	ZC3H12A	86	75.102	ENSLACG00000017365	ZC3H12A	97	54.958	Latimeria_chalumnae
ENSG00000163874	ZC3H12A	80	61.778	ENSLOCG00000017000	-	57	63.000	Lepisosteus_oculatus
ENSG00000163874	ZC3H12A	87	72.908	ENSLOCG00000003232	si:dkey-206d17.12	94	52.239	Lepisosteus_oculatus
ENSG00000163874	ZC3H12A	99	87.248	ENSLAFG00000018720	ZC3H12A	99	87.248	Loxodonta_africana
ENSG00000163874	ZC3H12A	100	97.005	ENSMFAG00000032647	ZC3H12A	100	97.005	Macaca_fascicularis
ENSG00000163874	ZC3H12A	100	97.005	ENSMMUG00000010323	ZC3H12A	100	97.005	Macaca_mulatta
ENSG00000163874	ZC3H12A	100	96.839	ENSMNEG00000040453	ZC3H12A	100	96.839	Macaca_nemestrina
ENSG00000163874	ZC3H12A	100	97.171	ENSMLEG00000034570	ZC3H12A	100	97.171	Mandrillus_leucophaeus
ENSG00000163874	ZC3H12A	95	53.763	ENSMAMG00000021794	-	99	53.737	Mastacembelus_armatus
ENSG00000163874	ZC3H12A	78	66.522	ENSMAMG00000004483	si:dkey-206d17.12	61	56.553	Mastacembelus_armatus
ENSG00000163874	ZC3H12A	84	65.863	ENSMAMG00000007494	zc3h12a	99	43.269	Mastacembelus_armatus
ENSG00000163874	ZC3H12A	95	55.109	ENSMAMG00000004463	-	100	54.317	Mastacembelus_armatus
ENSG00000163874	ZC3H12A	80	65.812	ENSMZEG00005023410	ZC3H12A	78	64.017	Maylandia_zebra
ENSG00000163874	ZC3H12A	80	65.812	ENSMZEG00005026287	si:dkey-206d17.12	90	44.481	Maylandia_zebra
ENSG00000163874	ZC3H12A	86	58.197	ENSMZEG00005015555	-	51	61.093	Maylandia_zebra
ENSG00000163874	ZC3H12A	79	63.436	ENSMZEG00005019137	-	87	51.007	Maylandia_zebra
ENSG00000163874	ZC3H12A	83	79.060	ENSMGAG00000003371	ZC3H12A	98	59.215	Meleagris_gallopavo
ENSG00000163874	ZC3H12A	96	87.546	ENSMAUG00000012893	Zc3h12a	100	81.469	Mesocricetus_auratus
ENSG00000163874	ZC3H12A	100	88.815	ENSMICG00000004790	ZC3H12A	100	88.648	Microcebus_murinus
ENSG00000163874	ZC3H12A	96	88.278	ENSMOCG00000001899	Zc3h12a	99	82.550	Microtus_ochrogaster
ENSG00000163874	ZC3H12A	92	53.435	ENSMMOG00000014855	-	97	52.290	Mola_mola
ENSG00000163874	ZC3H12A	80	66.087	ENSMMOG00000000727	zc3h12a	98	44.706	Mola_mola
ENSG00000163874	ZC3H12A	81	63.291	ENSMMOG00000013604	si:dkey-206d17.12	96	45.884	Mola_mola
ENSG00000163874	ZC3H12A	84	61.943	ENSMMOG00000005728	-	88	49.677	Mola_mola
ENSG00000163874	ZC3H12A	95	77.778	ENSMODG00000017794	ZC3H12A	99	65.815	Monodelphis_domestica
ENSG00000163874	ZC3H12A	80	61.966	ENSMALG00000012794	si:dkey-206d17.12	63	62.583	Monopterus_albus
ENSG00000163874	ZC3H12A	84	65.462	ENSMALG00000012319	zc3h12a	69	52.954	Monopterus_albus
ENSG00000163874	ZC3H12A	96	86.447	MGP_CAROLIEiJ_G0026462	Zc3h12a	100	81.970	Mus_caroli
ENSG00000163874	ZC3H12A	100	82.304	ENSMUSG00000042677	Zc3h12a	100	82.137	Mus_musculus
ENSG00000163874	ZC3H12A	96	85.348	MGP_PahariEiJ_G0028793	Zc3h12a	100	80.801	Mus_pahari
ENSG00000163874	ZC3H12A	100	82.304	MGP_SPRETEiJ_G0027441	Zc3h12a	100	84.588	Mus_spretus
ENSG00000163874	ZC3H12A	97	85.249	ENSMPUG00000014758	ZC3H12A	100	85.249	Mustela_putorius_furo
ENSG00000163874	ZC3H12A	99	85.092	ENSMLUG00000027279	ZC3H12A	99	84.757	Myotis_lucifugus
ENSG00000163874	ZC3H12A	96	89.011	ENSNGAG00000018725	Zc3h12a	100	84.551	Nannospalax_galili
ENSG00000163874	ZC3H12A	78	63.556	ENSNBRG00000012175	-	87	51.007	Neolamprologus_brichardi
ENSG00000163874	ZC3H12A	82	65.690	ENSNBRG00000009607	zc3h12a	66	54.801	Neolamprologus_brichardi
ENSG00000163874	ZC3H12A	87	57.874	ENSNBRG00000010961	-	91	57.143	Neolamprologus_brichardi
ENSG00000163874	ZC3H12A	83	63.115	ENSNBRG00000014376	si:dkey-206d17.12	52	64.952	Neolamprologus_brichardi
ENSG00000163874	ZC3H12A	100	91.152	ENSNLEG00000011545	ZC3H12A	100	91.152	Nomascus_leucogenys
ENSG00000163874	ZC3H12A	91	57.630	ENSMEUG00000003389	ZC3H12A	99	56.014	Notamacropus_eugenii
ENSG00000163874	ZC3H12A	75	84.479	ENSOPRG00000013711	ZC3H12A	100	84.479	Ochotona_princeps
ENSG00000163874	ZC3H12A	96	87.179	ENSODEG00000005643	ZC3H12A	99	82.915	Octodon_degus
ENSG00000163874	ZC3H12A	80	65.665	ENSONIG00000013685	si:dkey-206d17.12	97	47.679	Oreochromis_niloticus
ENSG00000163874	ZC3H12A	82	66.527	ENSONIG00000016235	zc3h12a	97	47.552	Oreochromis_niloticus
ENSG00000163874	ZC3H12A	91	53.716	ENSONIG00000012268	-	55	64.610	Oreochromis_niloticus
ENSG00000163874	ZC3H12A	87	79.365	ENSOANG00000002060	ZC3H12A	93	66.034	Ornithorhynchus_anatinus
ENSG00000163874	ZC3H12A	96	89.744	ENSOCUG00000010856	ZC3H12A	95	88.679	Oryctolagus_cuniculus
ENSG00000163874	ZC3H12A	82	65.401	ENSORLG00000014448	zc3h12a	95	44.265	Oryzias_latipes
ENSG00000163874	ZC3H12A	90	61.154	ENSORLG00000009473	ZC3H12A	93	61.686	Oryzias_latipes
ENSG00000163874	ZC3H12A	78	59.910	ENSORLG00000015280	-	53	61.246	Oryzias_latipes
ENSG00000163874	ZC3H12A	79	65.652	ENSORLG00020016107	-	70	55.904	Oryzias_latipes_hni
ENSG00000163874	ZC3H12A	78	59.910	ENSORLG00020008580	-	50	57.911	Oryzias_latipes_hni
ENSG00000163874	ZC3H12A	82	63.900	ENSORLG00020019555	zc3h12a	95	43.942	Oryzias_latipes_hni
ENSG00000163874	ZC3H12A	79	65.217	ENSORLG00015007634	ZC3H12A	70	55.797	Oryzias_latipes_hsok
ENSG00000163874	ZC3H12A	82	65.401	ENSORLG00015004539	zc3h12a	88	43.974	Oryzias_latipes_hsok
ENSG00000163874	ZC3H12A	78	59.910	ENSORLG00015003680	-	50	57.595	Oryzias_latipes_hsok
ENSG00000163874	ZC3H12A	79	67.826	ENSOMEG00000005602	si:dkey-206d17.12	68	55.718	Oryzias_melastigma
ENSG00000163874	ZC3H12A	78	59.471	ENSOMEG00000011669	-	53	62.284	Oryzias_melastigma
ENSG00000163874	ZC3H12A	82	64.407	ENSOMEG00000000483	zc3h12a	93	44.243	Oryzias_melastigma
ENSG00000163874	ZC3H12A	100	88.314	ENSOGAG00000030940	ZC3H12A	100	88.314	Otolemur_garnettii
ENSG00000163874	ZC3H12A	94	89.513	ENSOARG00000019760	ZC3H12A	99	86.014	Ovis_aries
ENSG00000163874	ZC3H12A	100	99.499	ENSPPAG00000041054	ZC3H12A	100	99.499	Pan_paniscus
ENSG00000163874	ZC3H12A	99	86.700	ENSPPRG00000014359	ZC3H12A	99	86.700	Panthera_pardus
ENSG00000163874	ZC3H12A	98	88.129	ENSPTIG00000012943	ZC3H12A	99	88.129	Panthera_tigris_altaica
ENSG00000163874	ZC3H12A	100	99.499	ENSPTRG00000000544	ZC3H12A	100	99.499	Pan_troglodytes
ENSG00000163874	ZC3H12A	100	97.171	ENSPANG00000011821	ZC3H12A	100	97.171	Papio_anubis
ENSG00000163874	ZC3H12A	95	51.852	ENSPKIG00000019720	-	88	50.909	Paramormyrops_kingsleyae
ENSG00000163874	ZC3H12A	80	71.681	ENSPKIG00000004769	zc3h12a	70	60.099	Paramormyrops_kingsleyae
ENSG00000163874	ZC3H12A	81	80.000	ENSPSIG00000009198	ZC3H12A	99	60.522	Pelodiscus_sinensis
ENSG00000163874	ZC3H12A	84	56.098	ENSPMGG00000004114	zc3h12a	98	42.808	Periophthalmus_magnuspinnatus
ENSG00000163874	ZC3H12A	85	61.826	ENSPMGG00000009790	-	57	65.287	Periophthalmus_magnuspinnatus
ENSG00000163874	ZC3H12A	100	83.806	ENSPEMG00000024080	Zc3h12a	100	83.806	Peromyscus_maniculatus_bairdii
ENSG00000163874	ZC3H12A	78	60.811	ENSPFOG00000004135	-	53	62.199	Poecilia_formosa
ENSG00000163874	ZC3H12A	78	63.913	ENSPMEG00000011188	si:dkey-206d17.12	50	64.664	Poecilia_mexicana
ENSG00000163874	ZC3H12A	86	57.202	ENSPMEG00000009279	-	96	56.557	Poecilia_mexicana
ENSG00000163874	ZC3H12A	97	55.160	ENSPREG00000001607	-	87	55.957	Poecilia_reticulata
ENSG00000163874	ZC3H12A	78	61.261	ENSPREG00000020369	-	55	56.677	Poecilia_reticulata
ENSG00000163874	ZC3H12A	100	98.164	ENSPPYG00000001534	ZC3H12A	100	98.164	Pongo_abelii
ENSG00000163874	ZC3H12A	74	85.393	ENSPCAG00000007720	ZC3H12A	99	85.393	Procavia_capensis
ENSG00000163874	ZC3H12A	100	88.982	ENSPCOG00000015837	ZC3H12A	100	88.815	Propithecus_coquereli
ENSG00000163874	ZC3H12A	75	86.253	ENSPVAG00000010120	ZC3H12A	75	86.031	Pteropus_vampyrus
ENSG00000163874	ZC3H12A	80	65.812	ENSPNYG00000003297	si:dkey-206d17.12	90	43.822	Pundamilia_nyererei
ENSG00000163874	ZC3H12A	86	58.197	ENSPNYG00000010663	-	51	61.093	Pundamilia_nyererei
ENSG00000163874	ZC3H12A	82	65.690	ENSPNYG00000013534	zc3h12a	50	65.015	Pundamilia_nyererei
ENSG00000163874	ZC3H12A	79	59.259	ENSPNAG00000012124	-	52	62.295	Pygocentrus_nattereri
ENSG00000163874	ZC3H12A	87	67.339	ENSPNAG00000010952	si:dkey-206d17.12	91	46.341	Pygocentrus_nattereri
ENSG00000163874	ZC3H12A	96	87.546	ENSRNOG00000009131	Zc3h12a	100	82.471	Rattus_norvegicus
ENSG00000163874	ZC3H12A	100	92.512	ENSRBIG00000042237	ZC3H12A	100	92.512	Rhinopithecus_bieti
ENSG00000163874	ZC3H12A	100	97.171	ENSRROG00000037444	ZC3H12A	100	97.171	Rhinopithecus_roxellana
ENSG00000163874	ZC3H12A	100	93.990	ENSSBOG00000028357	ZC3H12A	100	93.990	Saimiri_boliviensis_boliviensis
ENSG00000163874	ZC3H12A	75	68.323	ENSSHAG00000011780	-	99	66.460	Sarcophilus_harrisii
ENSG00000163874	ZC3H12A	64	74.866	ENSSFOG00015005925	zc3h12a	64	84.286	Scleropages_formosus
ENSG00000163874	ZC3H12A	84	64.143	ENSSMAG00000005140	zc3h12a	98	46.104	Scophthalmus_maximus
ENSG00000163874	ZC3H12A	89	61.132	ENSSDUG00000007162	si:dkey-206d17.12	79	52.455	Seriola_dumerili
ENSG00000163874	ZC3H12A	82	57.917	ENSSDUG00000010581	-	90	57.983	Seriola_dumerili
ENSG00000163874	ZC3H12A	82	66.807	ENSSDUG00000009879	zc3h12a	97	44.677	Seriola_dumerili
ENSG00000163874	ZC3H12A	83	61.382	ENSSDUG00000013237	-	89	56.250	Seriola_dumerili
ENSG00000163874	ZC3H12A	96	60.142	ENSSLDG00000009317	si:dkey-206d17.12	99	58.865	Seriola_lalandi_dorsalis
ENSG00000163874	ZC3H12A	84	56.967	ENSSLDG00000022022	-	50	60.000	Seriola_lalandi_dorsalis
ENSG00000163874	ZC3H12A	82	65.844	ENSSLDG00000003826	zc3h12a	97	44.911	Seriola_lalandi_dorsalis
ENSG00000163874	ZC3H12A	80	81.858	ENSSPUG00000003668	ZC3H12A	87	56.863	Sphenodon_punctatus
ENSG00000163874	ZC3H12A	84	66.667	ENSSPAG00000012466	zc3h12a	50	66.258	Stegastes_partitus
ENSG00000163874	ZC3H12A	80	66.520	ENSSPAG00000020938	si:dkey-206d17.12	95	48.479	Stegastes_partitus
ENSG00000163874	ZC3H12A	97	86.106	ENSSSCG00000037815	ZC3H12A	100	85.592	Sus_scrofa
ENSG00000163874	ZC3H12A	52	86.986	ENSTGUG00000001563	ZC3H12A	99	60.297	Taeniopygia_guttata
ENSG00000163874	ZC3H12A	78	66.957	ENSTRUG00000010565	si:dkey-206d17.12	97	47.377	Takifugu_rubripes
ENSG00000163874	ZC3H12A	80	65.778	ENSTNIG00000001274	si:dkey-206d17.12	57	64.052	Tetraodon_nigroviridis
ENSG00000163874	ZC3H12A	83	61.475	ENSTNIG00000014519	-	93	59.127	Tetraodon_nigroviridis
ENSG00000163874	ZC3H12A	96	68.978	ENSTBEG00000009789	-	76	79.121	Tupaia_belangeri
ENSG00000163874	ZC3H12A	100	87.646	ENSTTRG00000008591	ZC3H12A	100	87.646	Tursiops_truncatus
ENSG00000163874	ZC3H12A	99	85.953	ENSUAMG00000014105	ZC3H12A	99	86.218	Ursus_americanus
ENSG00000163874	ZC3H12A	97	86.621	ENSUMAG00000001122	ZC3H12A	100	86.621	Ursus_maritimus
ENSG00000163874	ZC3H12A	91	87.984	ENSVVUG00000023171	ZC3H12A	100	82.051	Vulpes_vulpes
ENSG00000163874	ZC3H12A	80	72.845	ENSXETG00000011465	zc3h12a	81	64.481	Xenopus_tropicalis
ENSG00000163874	ZC3H12A	82	63.900	ENSXCOG00000008984	zc3h12a	88	55.405	Xiphophorus_couchianus
ENSG00000163874	ZC3H12A	78	61.261	ENSXCOG00000001538	-	92	50.000	Xiphophorus_couchianus
ENSG00000163874	ZC3H12A	86	60.241	ENSXMAG00000014715	-	83	64.444	Xiphophorus_maculatus
ENSG00000163874	ZC3H12A	78	61.261	ENSXMAG00000005023	-	92	50.000	Xiphophorus_maculatus
ENSG00000163874	ZC3H12A	78	63.913	ENSXMAG00000025043	si:dkey-206d17.12	94	45.201	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay	-	ISS	Process
GO:0000932	P-body	22055188.26134560.	IDA	Component
GO:0001525	angiogenesis	-	IEA	Process
GO:0001933	negative regulation of protein phosphorylation	-	ISS	Process
GO:0002230	positive regulation of defense response to virus by host	23355615.	IDA	Process
GO:0002757	immune response-activating signal transduction	19909337.	IDA	Process
GO:0003677	DNA binding	18364357.	IDA	Function
GO:0003682	chromatin binding	18364357.	IDA	Function
GO:0003723	RNA binding	23355615.	IDA	Function
GO:0003729	mRNA binding	19909337.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	-	ISS	Function
GO:0004521	endoribonuclease activity	-	ISS	Function
GO:0004532	exoribonuclease activity	-	ISS	Function
GO:0004540	ribonuclease activity	23355615.	IDA	Function
GO:0004843	thiol-dependent ubiquitin-specific protease activity	25861989.	IMP	Function
GO:0005515	protein binding	16189514.21900206.21903422.21988832.24270572.25416956.25861989.26134560.	IPI	Function
GO:0005634	nucleus	16574901.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	18178554.19909337.	IDA	Component
GO:0005791	rough endoplasmic reticulum	-	ISS	Component
GO:0005856	cytoskeleton	19909337.	IDA	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0006954	inflammatory response	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	25861989.	IMP	Process
GO:0007399	nervous system development	-	IEA	Process
GO:0010468	regulation of gene expression	24048733.	IDA	Process
GO:0010508	positive regulation of autophagy	22739135.	IDA	Process
GO:0010595	positive regulation of endothelial cell migration	18364357.	IDA	Process
GO:0010628	positive regulation of gene expression	22739135.	IDA	Process
GO:0010629	negative regulation of gene expression	18178554.	IDA	Process
GO:0010656	negative regulation of muscle cell apoptotic process	-	ISS	Process
GO:0010884	positive regulation of lipid storage	22739135.	IDA	Process
GO:0010942	positive regulation of cell death	16574901.	IDA	Process
GO:0016579	protein deubiquitination	24048733.	IDA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0030867	rough endoplasmic reticulum membrane	-	IEA	Component
GO:0032088	negative regulation of NF-kappaB transcription factor activity	18178554.	IDA	Process
GO:0032715	negative regulation of interleukin-6 production	18178554.	IDA	Process
GO:0032720	negative regulation of tumor necrosis factor production	18178554.	IDA	Process
GO:0032991	protein-containing complex	25861989.	IDA	Component
GO:0034599	cellular response to oxidative stress	-	ISS	Process
GO:0035198	miRNA binding	22055188.	IDA	Function
GO:0035613	RNA stem-loop binding	-	ISS	Function
GO:0035925	mRNA 3'-UTR AU-rich region binding	-	ISS	Function
GO:0036464	cytoplasmic ribonucleoprotein granule	-	IDA	Component
GO:0042149	cellular response to glucose starvation	-	ISS	Process
GO:0042307	positive regulation of protein import into nucleus	24048733.	IDA	Process
GO:0042406	extrinsic component of endoplasmic reticulum membrane	-	ISS	Component
GO:0043022	ribosome binding	-	ISS	Function
GO:0043031	negative regulation of macrophage activation	18178554.	IC	Process
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	25861989.	IMP	Process
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	-	ISS	Process
GO:0044828	negative regulation by host of viral genome replication	23355615.	IDA	Process
GO:0045019	negative regulation of nitric oxide biosynthetic process	18178554.	IDA	Process
GO:0045600	positive regulation of fat cell differentiation	22739135.	IDA	Process
GO:0045766	positive regulation of angiogenesis	18364357.	IDA	Process
GO:0045766	positive regulation of angiogenesis	24048733.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	16574901.18364357.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0050713	negative regulation of interleukin-1 beta secretion	-	ISS	Process
GO:0050852	T cell receptor signaling pathway	-	ISS	Process
GO:0051259	protein complex oligomerization	22055188.23355615.	IDA	Process
GO:0051607	defense response to virus	-	IEA	Process
GO:0055118	negative regulation of cardiac muscle contraction	-	ISS	Process
GO:0061014	positive regulation of mRNA catabolic process	19909337.	IDA	Process
GO:0061014	positive regulation of mRNA catabolic process	-	ISS	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	19909337.	IDA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	-	ISS	Process
GO:0071222	cellular response to lipopolysaccharide	18178554.19909337.22055188.	IDA	Process
GO:0071222	cellular response to lipopolysaccharide	25861989.	IMP	Process
GO:0071347	cellular response to interleukin-1	-	ISS	Process
GO:0071356	cellular response to tumor necrosis factor	19909337.	IDA	Process
GO:0090501	RNA phosphodiester bond hydrolysis	-	ISS	Process
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	22055188.	IDA	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process
GO:0098586	cellular response to virus	23355615.	IDA	Process
GO:1900016	negative regulation of cytokine production involved in inflammatory response	-	ISS	Process
GO:1900119	positive regulation of execution phase of apoptosis	-	ISS	Process
GO:1900165	negative regulation of interleukin-6 secretion	-	ISS	Process
GO:1900745	positive regulation of p38MAPK cascade	24048733.	IDA	Process
GO:1901223	negative regulation of NIK/NF-kappaB signaling	-	ISS	Process
GO:1902714	negative regulation of interferon-gamma secretion	-	ISS	Process
GO:1903003	positive regulation of protein deubiquitination	25861989.	IMP	Process
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	22055188.	IDA	Process
GO:1903936	cellular response to sodium arsenite	-	ISS	Process
GO:1904468	negative regulation of tumor necrosis factor secretion	-	ISS	Process
GO:1904637	cellular response to ionomycin	-	ISS	Process
GO:1990869	cellular response to chemokine	16574901.18364357.	IDA	Process
GO:2000320	negative regulation of T-helper 17 cell differentiation	-	ISS	Process
GO:2000379	positive regulation of reactive oxygen species metabolic process	22739135.	IDA	Process
GO:2000627	positive regulation of miRNA catabolic process	22055188.24048733.	IDA	Process