EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000164151 (Gene tree)
Gene ID: 23379
Gene Symbol: ICE1
Alias: KIAA0947
Full Name: interactor of little elongation complex ELL subunit 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 69,571 bases
Position: chr5:5,420,664-5,490,234
Accession: 29154
RBP type: non-canonical RBP
Summary: (Interactor Of Little Elongation Complex ELL Subunit 1) is a Protein Coding gene. Among its related pathways are Tat-mediated elongation of the HIV-1 transcript and Gene Expression. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and lipid transporter activity. An important paralog of this gene is PAFAH1B3.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000296564	ICE1-201	7927	XM_011513999	ENSP00000296564	2266 (aa)	XP_011512301	Q9Y2F5
ENST00000512608	ICE1-203	613	-	ENSP00000485617	145 (aa)	-	A0A096LPH9
ENST00000505464	ICE1-202	1074	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000164151's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000164151	Cholesterol, LDL	6.07187478531834E-5	17903299
ENSG00000164151	Cholesterol, LDL	8.45932720099363E-5	17903299
ENSG00000164151	Cholesterol, LDL	6.44217335813154E-5	17903299
ENSG00000164151	Cholesterol, LDL	6.71965115107682E-5	17903299
ENSG00000164151	Triglycerides	3.66824933990505E-6	17903299
ENSG00000164151	Triglycerides	1.10420660356488E-6	17903299
ENSG00000164151	Cholesterol, LDL	9.9012152346926E-5	17903299
ENSG00000164151	Cholesterol, LDL	9.86046491937564E-5	17903299
ENSG00000164151	Lipoproteins, VLDL	6.3735017154193E-10	17903299
ENSG00000164151	Lipoproteins, VLDL	9.86385119814688E-11	17903299
ENSG00000164151	Lipids	7.27829925104562E-5	17903299
ENSG00000164151	Pulse	1.76156462162656E-6	17903302
ENSG00000164151	Pulse	3.89745136893539E-6	17903302
ENSG00000164151	Iron	1.7020000E-004	19880490
ENSG00000164151	Hemoglobin A, Glycosylated	6.7860000E-005	19875614
ENSG00000164151	gamma-Glutamyltransferase	6.301e-005	-
ENSG00000164151	Waist-Hip Ratio	7.4050000E-005	-
ENSG00000164151	Antihypertensive Agents	8.9830000E-006	-
ENSG00000164151	Antihypertensive Agents	5.0510000E-005	-
ENSG00000164151	Antihypertensive Agents	3.6710000E-005	-
ENSG00000164151	Coronary Disease	4.7040000E-005	-
ENSG00000164151	Coronary Disease	2.9200000E-005	-
ENSG00000164151	Coronary Disease	4.7730000E-005	-
ENSG00000164151	Glomerular Filtration Rate	8.7311299E-005	-
ENSG00000164151	Platelet Function Tests	7.6651846E-006	-
ENSG00000164151	Platelet Function Tests	3.0256000E-005	-
ENSG00000164151	Electrocardiography	1E-6	20031603
ENSG00000164151	Paliperidone Palmitate	5E-6	27846195
ENSG00000164151	Schizophrenia	5E-6	27846195
ENSG00000164151	Alcohol Drinking	2E-6	24376456
ENSG00000164151	Arterial Pressure	2E-6	24376456
ENSG00000164151	Disease-Free Survival	2E-9	17903295
ENSG00000164151	Paliperidone Palmitate	8E-6	27846195
ENSG00000164151	Schizophrenia	8E-6	27846195

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000164151's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000164151	ICE1	99	95.833	ENSMUSG00000034525	Ice1	93	89.899	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	22195968.23932780.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0008023	transcription elongation factor complex	23932780.	IDA	Component
GO:0015030	Cajal body	22195968.23932780.	IDA	Component
GO:0016604	nuclear body	-	IDA	Component
GO:0031334	positive regulation of protein complex assembly	23932780.	IMP	Process
GO:0035327	transcriptionally active chromatin	22195968.23932780.	IDA	Component
GO:0035363	histone locus body	23932780.	IDA	Component
GO:0042795	snRNA transcription by RNA polymerase II	22195968.23932780.	IMP	Process
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process
GO:0042796	snRNA transcription by RNA polymerase III	23932780.	IMP	Process
GO:0042803	protein homodimerization activity	23932780.	TAS	Function
GO:0045945	positive regulation of transcription by RNA polymerase III	23932780.	IMP	Process
GO:0090316	positive regulation of intracellular protein transport	23932780.	IMP	Process