EuRBPDB

Description

RBDs

PRI

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000164252 (Gene tree)
Gene ID: 55109
Gene Symbol: AGGF1
Alias: VG5Q|HSU84971|FLJ10283|GPATC7|GPATCH7
Full Name: angiogenic factor with G-patch and FHA domains 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 35,984 bases
Position: chr5:77,029,251-77,065,234
Accession: 24684
RBP type: canonical RBP
Summary: This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000316109	G-patch	PF01585.23	3.7e-13	1	1

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15486042	OCRE: a novel domain made of imperfect, aromatic-rich octamer repeats.	Bioinformatics	2005 Mar	Callebaut I	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000503538	AGGF1-203	552	-	-	- (aa)	-	-
ENST00000502408	AGGF1-202	825	-	ENSP00000420874	87 (aa)	-	H0Y8F8
ENST00000506806	AGGF1-204	1142	-	ENSP00000424733	176 (aa)	-	Q8N302
ENST00000312916	AGGF1-201	4509	-	ENSP00000316109	714 (aa)	-	Q8N302

Gene Model

Click here to download ENSG00000164252's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000164252	Platelet Function Tests	1.2080013E-006	-
ENSG00000164252	coenzyme Q10	6E-6	27149984

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000164252	rs13155649	5	77031745	G	Coenzyme Q10 levels	27149984	[0.058-0.145] unit increase	0.101	EFO_0007836

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000164252's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000164252	AGGF1	97	89.625	ENSAMEG00000001833	-	97	89.640	Ailuropoda_melanoleuca
ENSG00000164252	AGGF1	97	46.373	ENSACIG00000016886	aggf1	95	46.857	Amphilophus_citrinellus
ENSG00000164252	AGGF1	77	60.452	ENSAOCG00000003993	aggf1	79	60.734	Amphiprion_ocellaris
ENSG00000164252	AGGF1	86	52.985	ENSATEG00000023889	aggf1	94	53.905	Anabas_testudineus
ENSG00000164252	AGGF1	90	64.024	ENSAPLG00000001528	-	100	64.134	Anas_platyrhynchos
ENSG00000164252	AGGF1	95	58.621	ENSACAG00000007847	-	98	58.705	Anolis_carolinensis
ENSG00000164252	AGGF1	97	95.965	ENSANAG00000023021	-	98	95.960	Aotus_nancymaae
ENSG00000164252	AGGF1	97	44.695	ENSACLG00000010679	aggf1	96	46.585	Astatotilapia_calliptera
ENSG00000164252	AGGF1	97	88.133	ENSBTAG00000034823	AGGF1	97	88.167	Bos_taurus
ENSG00000164252	AGGF1	97	95.677	ENSCJAG00000019955	-	98	95.671	Callithrix_jacchus
ENSG00000164252	AGGF1	97	89.177	ENSCAFG00000009268	AGGF1	97	89.177	Canis_familiaris
ENSG00000164252	AGGF1	97	89.177	ENSCAFG00020025988	-	97	89.177	Canis_lupus_dingo
ENSG00000164252	AGGF1	97	88.439	ENSCHIG00000012662	-	97	88.456	Capra_hircus
ENSG00000164252	AGGF1	97	90.058	ENSTSYG00000012743	-	97	90.043	Carlito_syrichta
ENSG00000164252	AGGF1	89	73.155	ENSCAPG00000010308	-	99	73.155	Cavia_aperea
ENSG00000164252	AGGF1	98	82.783	ENSCPOG00000003545	-	96	82.634	Cavia_porcellus
ENSG00000164252	AGGF1	97	94.835	ENSCCAG00000023174	-	96	94.828	Cebus_capucinus
ENSG00000164252	AGGF1	100	96.499	ENSCATG00000041518	-	100	96.499	Cercocebus_atys
ENSG00000164252	AGGF1	97	83.046	ENSCLAG00000012928	-	96	82.973	Chinchilla_lanigera
ENSG00000164252	AGGF1	100	96.359	ENSCSAG00000015324	-	100	96.359	Chlorocebus_sabaeus
ENSG00000164252	AGGF1	99	65.223	ENSCPBG00000001764	-	98	64.681	Chrysemys_picta_bellii
ENSG00000164252	AGGF1	100	96.218	ENSCANG00000042628	-	100	96.218	Colobus_angolensis_palliatus
ENSG00000164252	AGGF1	97	79.971	ENSCGRG00001017039	Aggf1	98	80.692	Cricetulus_griseus_chok1gshd
ENSG00000164252	AGGF1	92	79.847	ENSCGRG00000010170	Aggf1	100	80.305	Cricetulus_griseus_crigri
ENSG00000164252	AGGF1	97	46.080	ENSCSEG00000007246	aggf1	96	42.246	Cynoglossus_semilaevis
ENSG00000164252	AGGF1	96	44.837	ENSCVAG00000002578	aggf1	96	44.626	Cyprinodon_variegatus
ENSG00000164252	AGGF1	97	88.058	ENSDNOG00000018473	-	96	88.761	Dasypus_novemcinctus
ENSG00000164252	AGGF1	97	79.167	ENSDORG00000005780	Aggf1	97	79.340	Dipodomys_ordii
ENSG00000164252	AGGF1	97	88.857	ENSEASG00005001829	-	97	88.889	Equus_asinus_asinus
ENSG00000164252	AGGF1	97	89.146	ENSECAG00000016031	AGGF1	99	88.707	Equus_caballus
ENSG00000164252	AGGF1	82	89.941	ENSEEUG00000008338	-	91	89.941	Erinaceus_europaeus
ENSG00000164252	AGGF1	97	89.884	ENSFCAG00000018724	-	97	89.899	Felis_catus
ENSG00000164252	AGGF1	90	65.138	ENSFALG00000010018	-	91	65.443	Ficedula_albicollis
ENSG00000164252	AGGF1	97	84.052	ENSFDAG00000017381	-	96	83.983	Fukomys_damarensis
ENSG00000164252	AGGF1	96	44.110	ENSFHEG00000003864	aggf1	95	44.973	Fundulus_heteroclitus
ENSG00000164252	AGGF1	98	62.482	ENSGALG00000004311	-	99	62.837	Gallus_gallus
ENSG00000164252	AGGF1	97	44.624	ENSGAFG00000008721	aggf1	96	44.758	Gambusia_affinis
ENSG00000164252	AGGF1	99	65.223	ENSGAGG00000016181	-	98	64.539	Gopherus_agassizii
ENSG00000164252	AGGF1	100	98.601	ENSGGOG00000010269	-	100	98.601	Gorilla_gorilla
ENSG00000164252	AGGF1	97	44.695	ENSHBUG00000022352	aggf1	96	45.541	Haplochromis_burtoni
ENSG00000164252	AGGF1	97	83.908	ENSHGLG00000000455	-	96	83.838	Heterocephalus_glaber_female
ENSG00000164252	AGGF1	97	83.908	ENSHGLG00100003212	-	96	83.838	Heterocephalus_glaber_male
ENSG00000164252	AGGF1	97	87.644	ENSSTOG00000021590	-	97	87.590	Ictidomys_tridecemlineatus
ENSG00000164252	AGGF1	97	78.305	ENSJJAG00000012003	Aggf1	97	78.211	Jaculus_jaculus
ENSG00000164252	AGGF1	97	45.986	ENSKMAG00000000429	aggf1	96	46.238	Kryptolebias_marmoratus
ENSG00000164252	AGGF1	98	55.462	ENSLACG00000012448	aggf1	97	55.163	Latimeria_chalumnae
ENSG00000164252	AGGF1	97	49.792	ENSLOCG00000005688	aggf1	98	50.425	Lepisosteus_oculatus
ENSG00000164252	AGGF1	100	96.919	ENSMFAG00000038062	-	100	96.919	Macaca_fascicularis
ENSG00000164252	AGGF1	100	96.919	ENSMMUG00000021356	AGGF1	100	96.919	Macaca_mulatta
ENSG00000164252	AGGF1	100	96.919	ENSMNEG00000044235	-	100	96.919	Macaca_nemestrina
ENSG00000164252	AGGF1	100	96.779	ENSMLEG00000031926	-	100	96.779	Mandrillus_leucophaeus
ENSG00000164252	AGGF1	97	46.102	ENSMAMG00000018109	aggf1	96	45.369	Mastacembelus_armatus
ENSG00000164252	AGGF1	68	82.510	ENSMAUG00000012678	Aggf1	94	71.148	Mesocricetus_auratus
ENSG00000164252	AGGF1	97	90.374	ENSMICG00000028679	-	97	90.332	Microcebus_murinus
ENSG00000164252	AGGF1	97	79.509	ENSMOCG00000003377	Aggf1	97	79.509	Microtus_ochrogaster
ENSG00000164252	AGGF1	97	76.109	ENSMODG00000019743	-	97	76.109	Monodelphis_domestica
ENSG00000164252	AGGF1	97	45.479	ENSMALG00000000629	aggf1	78	61.453	Monopterus_albus
ENSG00000164252	AGGF1	97	77.778	MGP_CAROLIEiJ_G0018795	Aggf1	97	77.778	Mus_caroli
ENSG00000164252	AGGF1	97	77.922	ENSMUSG00000021681	Aggf1	97	77.922	Mus_musculus
ENSG00000164252	AGGF1	97	78.355	MGP_PahariEiJ_G0015872	Aggf1	97	78.355	Mus_pahari
ENSG00000164252	AGGF1	97	78.066	MGP_SPRETEiJ_G0019678	Aggf1	97	78.066	Mus_spretus
ENSG00000164252	AGGF1	100	88.827	ENSMPUG00000005518	-	97	89.209	Mustela_putorius_furo
ENSG00000164252	AGGF1	97	88.745	ENSMLUG00000016792	-	97	88.745	Myotis_lucifugus
ENSG00000164252	AGGF1	97	84.993	ENSNGAG00000008354	Aggf1	98	84.993	Nannospalax_galili
ENSG00000164252	AGGF1	97	44.892	ENSNBRG00000016805	aggf1	91	45.604	Neolamprologus_brichardi
ENSG00000164252	AGGF1	98	97.674	ENSNLEG00000026907	-	100	93.137	Nomascus_leucogenys
ENSG00000164252	AGGF1	75	81.818	ENSMEUG00000003694	-	88	81.818	Notamacropus_eugenii
ENSG00000164252	AGGF1	97	82.759	ENSODEG00000000501	-	96	82.684	Octodon_degus
ENSG00000164252	AGGF1	97	46.489	ENSONIG00000019429	aggf1	99	47.740	Oreochromis_niloticus
ENSG00000164252	AGGF1	90	72.451	ENSOANG00000015762	-	100	72.451	Ornithorhynchus_anatinus
ENSG00000164252	AGGF1	82	71.502	ENSOCUG00000021999	-	89	71.502	Oryctolagus_cuniculus
ENSG00000164252	AGGF1	58	66.265	ENSOCUG00000022939	-	99	65.542	Oryctolagus_cuniculus
ENSG00000164252	AGGF1	97	88.473	ENSOGAG00000003439	-	97	88.456	Otolemur_garnettii
ENSG00000164252	AGGF1	97	88.423	ENSOARG00000016987	-	97	88.456	Ovis_aries
ENSG00000164252	AGGF1	100	98.319	ENSPPAG00000035969	-	100	98.319	Pan_paniscus
ENSG00000164252	AGGF1	100	89.496	ENSPPRG00000004438	-	97	90.043	Panthera_pardus
ENSG00000164252	AGGF1	100	89.496	ENSPTIG00000021519	-	97	89.899	Panthera_tigris_altaica
ENSG00000164252	AGGF1	100	98.739	ENSPTRG00000017008	AGGF1	100	98.739	Pan_troglodytes
ENSG00000164252	AGGF1	100	96.919	ENSPANG00000026423	-	100	96.919	Papio_anubis
ENSG00000164252	AGGF1	91	65.419	ENSPSIG00000014397	-	99	70.826	Pelodiscus_sinensis
ENSG00000164252	AGGF1	97	80.952	ENSPEMG00000015659	Aggf1	97	80.952	Peromyscus_maniculatus_bairdii
ENSG00000164252	AGGF1	76	48.022	ENSPMAG00000000248	aggf1	99	49.189	Petromyzon_marinus
ENSG00000164252	AGGF1	98	75.779	ENSPCIG00000002077	-	96	75.892	Phascolarctos_cinereus
ENSG00000164252	AGGF1	84	52.087	ENSPREG00000000844	aggf1	92	51.724	Poecilia_reticulata
ENSG00000164252	AGGF1	100	98.039	ENSPPYG00000015574	-	100	98.039	Pongo_abelii
ENSG00000164252	AGGF1	85	88.179	ENSPCAG00000001207	-	78	88.424	Procavia_capensis
ENSG00000164252	AGGF1	97	90.374	ENSPCOG00000026723	-	97	90.332	Propithecus_coquereli
ENSG00000164252	AGGF1	82	88.104	ENSPVAG00000009733	-	81	88.104	Pteropus_vampyrus
ENSG00000164252	AGGF1	97	44.636	ENSPNYG00000004829	aggf1	96	46.995	Pundamilia_nyererei
ENSG00000164252	AGGF1	97	76.513	ENSRNOG00000029304	Aggf1	98	76.513	Rattus_norvegicus
ENSG00000164252	AGGF1	97	92.063	ENSRBIG00000041741	-	97	92.063	Rhinopithecus_bieti
ENSG00000164252	AGGF1	97	95.245	ENSSBOG00000019539	-	98	95.238	Saimiri_boliviensis_boliviensis
ENSG00000164252	AGGF1	97	76.245	ENSSHAG00000004570	-	97	75.714	Sarcophilus_harrisii
ENSG00000164252	AGGF1	97	47.383	ENSSFOG00015016459	aggf1	97	49.211	Scleropages_formosus
ENSG00000164252	AGGF1	85	80.820	ENSSARG00000004985	-	100	80.820	Sorex_araneus
ENSG00000164252	AGGF1	98	61.872	ENSSPUG00000016142	-	98	62.642	Sphenodon_punctatus
ENSG00000164252	AGGF1	83	64.602	ENSSPAG00000013607	aggf1	96	47.009	Stegastes_partitus
ENSG00000164252	AGGF1	97	89.001	ENSSSCG00000014094	-	97	89.033	Sus_scrofa
ENSG00000164252	AGGF1	90	64.438	ENSTGUG00000004021	-	100	64.590	Taeniopygia_guttata
ENSG00000164252	AGGF1	97	44.602	ENSTNIG00000011002	aggf1	97	45.143	Tetraodon_nigroviridis
ENSG00000164252	AGGF1	86	78.289	ENSTBEG00000006876	-	78	78.146	Tupaia_belangeri
ENSG00000164252	AGGF1	97	86.975	ENSTTRG00000009470	-	97	87.013	Tursiops_truncatus
ENSG00000164252	AGGF1	97	90.058	ENSUAMG00000026527	-	97	90.072	Ursus_americanus
ENSG00000164252	AGGF1	97	90.058	ENSUMAG00000005048	-	97	90.072	Ursus_maritimus
ENSG00000164252	AGGF1	97	84.416	ENSVPAG00000001901	-	98	84.416	Vicugna_pacos
ENSG00000164252	AGGF1	97	87.464	ENSVVUG00000025114	-	98	87.752	Vulpes_vulpes
ENSG00000164252	AGGF1	99	52.559	ENSXETG00000017077	aggf1	91	69.312	Xenopus_tropicalis
ENSG00000164252	AGGF1	97	40.671	ENSXCOG00000017629	aggf1	74	51.524	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001525	angiogenesis	-	IEA	Process
GO:0001570	vasculogenesis	15905966.	TAS	Process
GO:0001938	positive regulation of endothelial cell proliferation	14961121.	IDA	Process
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0005515	protein binding	14961121.	IPI	Function
GO:0005576	extracellular region	14961121.	IDA	Component
GO:0005737	cytoplasm	14961121.	IDA	Component
GO:0007155	cell adhesion	14961121.	IDA	Process
GO:0045766	positive regulation of angiogenesis	21873635.	IBA	Process
GO:0045766	positive regulation of angiogenesis	14961121.	IDA	Process
GO:0048471	perinuclear region of cytoplasm	14961121.	IDA	Component