24633336 | P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma. | Cancer Immunol Immunother | 2014 May | Terashima T | doi: 10.1007/s00262-014-1529-8 |
22842823 | Therapeutic efficacy of an hTERT promoter-driven oncolytic adenovirus that expresses apoptin in gastric carcinoma. | Int J Mol Med | 2012 Oct | Liu L | doi: 10.3892/ijmm.2012.1077 |
29019414 | The TERT hypermethylated oncologic region predicts recurrence and survival in pancreatic cancer. | Future Oncol | 2017 Oct | Faleiro I | doi: 10.2217/fon-2017-0167 |
11936586 | Telomerase activity in breast cancer in Western India (Gujarat). | Int J Biol Markers | 2002 Jan-Mar | Shah NG | - |
28247570 | Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c-Myc expression. | Cancer Med | 2017 Apr | Wang X | doi: 10.1002/cam4.999 |
21193962 | Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression. | Mol Cells | 2011 Jan | Beck S | doi: 10.1007/s10059-011-0008-8 |
22527847 | Circulating cell-free human telomerase reverse transcriptase mRNA in plasma and its potential diagnostic and prognostic value for gastric cancer. | Int J Clin Oncol | 2013 Jun | Kang Y | doi: 10.1007/s10147-012-0405-9 |
15989808 | [Study on apoptosis of human cervical carcinoma HeLa cells with RNA interference targeting hTERT]. | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | 2005 Jul | Zhao Y | - |
26772886 | miR-1182 inhibits growth and mediates the chemosensitivity of bladder cancer by targeting hTERT. | Biochem Biophys Res Commun | 2016 Feb 5 | Zhou J | doi: 10.1016/j.bbrc.2016.01.014 |
15138842 | Immunohistochemical localization of hTERT protein in human tissues. | Histochem Cell Biol | 2004 May | Yan P | - |
18437586 | Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer. | Artif Cells Blood Substit Immobil Biotechnol | 2008 | Tang J | doi: 10.1080/10731190801932074. |
21319134 | Evaluation of serum human telomerase reverse transcriptase as a novel marker for cervical cancer. | Int J Biol Markers | 2011 Jan-Mar | Porika M | - |
27072825 | Shorter telomeres and high telomerase activity correlate with a highly aggressive phenotype in breast cancer cell lines. | Tumour Biol | 2016 Sep | Ceja-Rangel HA | - |
25584719 | Association of TERT promoter mutation 1,295,228 C>T with BRAF V600E mutation, older patient age, and distant metastasis in anaplastic thyroid cancer. | J Clin Endocrinol Metab | 2015 Apr | Shi X | doi: 10.1210/jc.2014-3606 |
19596972 | Circulating hTERT DNA in early breast cancer. | Anticancer Res | 2009 Jul | Divella R | - |
24154961 | Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. | Acta Neuropathol | 2013 Dec | Koelsche C | doi: 10.1007/s00401-013-1195-5 |
18584973 | Immunohistochemical localization of telomerase in myomas and in uterine myometrium. | Pathol Res Pract | 2008 | Madej P | doi: 10.1016/j.prp.2008.02.006 |
16388756 | [Construction of tumor cell-specific expression vector modulated by human telomerase reserse transcription gene core promoter]. | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | 2006 Jan | Li HM | - |
21553236 | Telomerase reverse transcriptase catalytic subunit expression and proliferation index in Wilms tumor. | Tumour Biol | 2011 Aug | Diniz G | doi: 10.1007/s13277-011-0178-1 |
30419422 | BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits. | Redox Biol | 2019 Jan | Zhao X | doi: 10.1016/j.redox.2018.10.018 |
20032382 | Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer. | Anticancer Res | 2009 Nov | Schjlberg AR | - |
26061753 | Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. | N Engl J Med | 2015 Jun 25 | Eckel-Passow JE | doi: 10.1056/NEJMoa1407279 |
12218171 | Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells. | Proc Natl Acad Sci U S A | 2002 Sep 17 | Hernandez J | - |
19301721 | Human telomerase reverse transcriptase (hTERT) expression in borderline ovarian tumors: an immunohistochemical study. | J Med Assoc Thai | 2009 Mar | Tantbirojn P | - |
18451164 | Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization. | Cancer Res | 2008 May 1 | Agarwal M | doi: 10.1158/0008-5472.CAN-07-5831. |
17961306 | Analysis of hTERT expression in exfoliated cells from patients with bladder transitional cell carcinomas using SYBR green real-time fluorescence quantitative PCR. | Ann Clin Biochem | 2007 Nov | Xie XY | - |
18276798 | Multistep regulation of telomerase during differentiation of HL60 cells. | J Leukoc Biol | 2008 May | Yamada O | doi: 10.1189/jlb.1207848 |
25225064 | Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer. | Clin Cancer Res | 2014 Sep 15 | Nickerson ML | doi: 10.1158/1078-0432.CCR-14-0330. |
18204433 | Distribution and prognostic significance of human telomerase reverse transcriptase (hTERT) expression in giant-cell tumor of bone. | Mod Pathol | 2008 Apr | Horvai AE | doi: 10.1038/modpathol.3801015 |
11855854 | The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. | Exp Cell Res | 2002 Mar 10 | Hou M | - |
17172814 | hTERT/re-caspase-3 system induce apoptosis in hTERT-positive cancer cells. | Cancer Biol Ther | 2006 Nov | Yang LF | - |
16830373 | Circulating hTERT mRNA as a tumor marker in cholangiocarcinoma patients. | World J Gastroenterol | 2006 Jul 14 | Leelawat K | - |
18250061 | [Expression of human telomerase reverse transcriptase in renal cell carcinoma and its clinical significance]. | Nan Fang Yi Ke Da Xue Xue Bao | 2008 Feb | Wu P | - |
24562933 | Biological differential diagnosis of follicular thyroid tumor and H??rthle cell tumor on the basis of telomere length and hTERT expression. | Ann Surg Oncol | 2014 Jul | Sugishita Y | doi: 10.1245/s10434-014-3552-6 |
26398300 | Antitumor effect of COOH-terminal polypeptide of human TERT is associated with the declined expression of hTERT and NF-??B p65 in HeLa cells. | Oncol Rep | 2015 Dec | Wu X | doi: 10.3892/or.2015.4298 |
22916267 | Cell-free circulating plasma hTERT mRNA is a useful marker for prostate cancer diagnosis and is associated with poor prognosis tumor characteristics. | PLoS One | 2012 | March-Villalba JA | doi: 10.1371/journal.pone.0043470 |
25159205 | Prevalence and implications of TERT promoter mutation in uveal and conjunctival melanoma and in benign and premalignant conjunctival melanocytic lesions. | Invest Ophthalmol Vis Sci | 2014 Aug 26 | Koopmans AE | doi: 10.1167/iovs.14-14901. |
12231532 | hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer. | Clin Cancer Res | 2002 Sep | Wang L | - |
26597176 | Somatic and germline analyses of a long term melanoma survivor with a recurrent brain metastasis. | BMC Cancer | 2015 Nov 23 | Weiss S | doi: 10.1186/s12885-015-1927-0. |
21730156 | Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. | Proc Natl Acad Sci U S A | 2011 Dec 20 | Okamoto N | doi: 10.1073/pnas.1015171108 |
25870252 | Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT. | Endocr Relat Cancer | 2015 Jun | Dettmer MS | doi: 10.1530/ERC-15-0057 |
19587531 | Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis. | Cancer Biol Ther | 2009 May | Zang G | - |
26258591 | miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo. | PLoS One | 2015 Aug 10 | Li J | doi: 10.1371/journal.pone.0135265 |
17974918 | The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. | Genes Dev | 2007 Nov 1 | Okawa T | - |
20482774 | A novel biomarker TERTmRNA is applicable for early detection of hepatoma. | BMC Gastroenterol | 2010 May 18 | Miura N | doi: 10.1186/1471-230X-10-46. |
26953344 | Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. | J Biol Chem | 2016 Apr 29 | Suryo Rahmanto Y | doi: 10.1074/jbc.M115.707612 |
21261472 | Proteomic studies coupled with RNAi methodologies can shed further light on the downstream effects of telomerase in glioma. | Cancer Invest | 2011 Feb | Thakkar D | doi: 10.3109/07357907.2010.543212. |
24101484 | TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism. | Proc Natl Acad Sci U S A | 2013 Oct 22 | Rachakonda PS | doi: 10.1073/pnas.1310522110 |
20876690 | BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells. | Nucleic Acids Res | 2011 Feb | Renaud S | doi: 10.1093/nar/gkq827 |
22948024 | Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome. | Eur J Hum Genet | 2013 May | Bellido F | doi: 10.1038/ejhg.2012.204 |
18027853 | Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts. | Int J Cancer | 2008 Mar 15 | Falchetti ML | - |
23441130 | The roles of telomerase in the generation of polyploidy during neoplastic cell growth. | Neoplasia | 2013 Feb | Christodoulidou A | - |
24746472 | TERT attenuated ER stress-induced cell death. | Biochem Biophys Res Commun | 2014 May 2 | Hosoi T | doi: 10.1016/j.bbrc.2014.04.034 |
15326479 | Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance. | Oncogene | 2004 Sep 30 | Dudognon C | - |
26617880 | TERT promoter mutated WHO grades II and III gliomas are located preferentially in the frontal lobe and avoid the midline. | Int J Clin Exp Pathol | 2015 Sep 1 | Sun ZL | - |
25583906 | TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma. | Eur J Endocrinol | 2015 Apr | Gandolfi G | doi: 10.1530/EJE-14-0837 |
26418880 | Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells. | Oncotarget | 2015 Oct 20 | Chen R | doi: 10.18632/oncotarget.5301. |
22720091 | The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironment. | PLoS One | 2012 | Hashimoto Y | doi: 10.1371/journal.pone.0039292 |
12759234 | hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors. | Am J Pathol | 2003 Jun | Fan X | - |
23641014 | Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia. | Blood | 2013 Jun 13 | Miyazaki Y | doi: 10.1182/blood-2012-11-465971 |
15094035 | On the road to immortality: hTERT upregulation in cancer cells. | FEBS Lett | 2004 Apr 23 | Janknecht R | - |
15263087 | Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells. | Proc Natl Acad Sci U S A | 2004 Aug 3 | Won J | - |
12517770 | Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein. | Cancer Res | 2003 Jan 1 | Akiyama M | - |
19934306 | Combination of hTERT knockdown and IFN-gamma treatment inhibited angiogenesis and tumor progression in glioblastoma. | Clin Cancer Res | 2009 Dec 1 | George J | doi: 10.1158/1078-0432.CCR-09-1425 |
22559196 | Plasma hTERT mRNA discriminates between clinically localized and locally advanced disease and is a predictor of recurrence in prostate cancer patients. | Expert Opin Biol Ther | 2012 Jun | March-Villalba JA | doi: 10.1517/14712598.2012.685716 |
26082434 | Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. | Sci Signal | 2015 Jun 16 | Panneer Selvam S | doi: 10.1126/scisignal.aaa4998. |
26669682 | Aberrant methylation of the TERT promoter in esophageal squamous cell carcinoma. | Cancer Genet | 2015 Dec | Deng J | doi: 10.1016/j.cancergen.2015.10.004 |
22768805 | hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions. | BMC Gastroenterol | 2012 Jul 6 | Silva TC | doi: 10.1186/1471-230X-12-85. |
12839932 | Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase. | Cancer Res | 2003 Jul 1 | Folini M | - |
16202213 | Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast. | J Cell Mol Med | 2005 Jul-Sep | Mukhopadhyay NK | - |
16708388 | Enhanced antitumor effect against human telomerase reverse transcriptase (hTERT) by vaccination with chemotactic-hTERT gene-modified tumor cell and the combination with anti-4-1BB monoclonal antibodies. | Int J Cancer | 2006 Oct 15 | Lin X | - |
19885561 | Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues. | Int J Oncol | 2009 Dec | Fabricius EM | - |
12368310 | Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells. | J Virol | 2002 Nov | Yuan H | - |
20571066 | Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. | Mol Cancer Ther | 2010 Jul | Liu S | doi: 10.1158/1535-7163.MCT-09-0924 |
18511807 | Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells. | Blood | 2008 Oct 1 | Bellon M | doi: 10.1182/blood-2008-01-134692 |
14981931 | Development of a highly sensitive RT-PCR luminometric hybridization assay for human telomerase reverse-transcriptase beta-plus transcript. | Anticancer Res | 2003 Nov-Dec | Angelopoulou K | - |
16020509 | Tumor necrosis factor-alpha inhibits hTERT gene expression in human myeloid normal and leukemic cells. | Blood | 2005 Nov 1 | Beyne-Rauzy O | - |
26354077 | TERT promoter mutations in thyroid cancer: a report from a Middle Eastern population. | Endocr Relat Cancer | 2015 Dec | Qasem E | doi: 10.1530/ERC-15-0396 |
15746653 | Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells. | J Lab Clin Med | 2005 Feb | Zhang X | - |
27040924 | Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications. | Ann Diagn Pathol | 2016 Apr | Kurtis B | doi: 10.1016/j.anndiagpath.2015.12.002 |
27336831 | Association Between Human Telomerase Reverse Transcriptase Gene Variations and Risk of Developing Breast Cancer. | Genet Test Mol Biomarkers | 2016 Aug | Oztas E | doi: 10.1089/gtmb.2015.0339 |
28052688 | TERT promoter mutation status in sarcomatoid urothelial carcinomas of the upper urinary tract. | Future Oncol | 2017 Apr | Wang X | doi: 10.2217/fon-2016-0414 |
27325744 | hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor. | Nucleic Acids Res | 2016 Oct 14 | Liu N | - |
28443470 | A multi-target protein of hTERTR-FAM96A presents significant anticancer potent in the treatment of hepatocellular carcinoma. | Tumour Biol | 2017 Apr | Zhang MY | doi: 10.1177/1010428317698341. |
28209613 | WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells. | Cancer Res | 2017 May 1 | Zhang K | doi: 10.1158/0008-5472.CAN-16-1887 |
28025427 | The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma. | J Oral Sci | 2016 | Carkic J | doi: 10.2334/josnusd.16-0108. |
27157859 | CCL21/IL21-armed oncolytic adenovirus enhances antitumor activity against TERT-positive tumor cells. | Virus Res | 2016 Jul 15 | Li Y | doi: 10.1016/j.virusres.2016.05.002 |
27982019 | The associations of TERT-CLPTM1L variants and TERT mRNA expression with the prognosis of early stage non-small cell lung cancer. | Cancer Gene Ther | 2017 Jan | Chen Z | doi: 10.1038/cgt.2016.74 |
27562490 | TERT promoter mutations and prognosis in solitary fibrous tumor. | Mod Pathol | 2016 Dec | Bahrami A | doi: 10.1038/modpathol.2016.126 |
28039467 | Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity. | Oncotarget | 2017 Feb 7 | Bonuccelli G | doi: 10.18632/oncotarget.14196. |
28894890 | New prognostic factor telomerase reverse transcriptase promotor mutation presents without MR imaging biomarkers in primary glioblastoma. | Neuroradiology | 2017 Dec | Ersoy TF | doi: 10.1007/s00234-017-1920-1 |
29860064 | Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer. | Gene | 2018 Sep 25 | Alsiary R | doi: 10.1016/j.gene.2018.05.113 |
28829509 | Clinical significance of PSMA, TERT and PDEF in malignant tumors of the prostate. | Eur Rev Med Pharmacol Sci | 2017 Aug | Situ J | - |
29463038 | Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas. | Int J Mol Sci | 2018 Feb 18 | Ferreira MSV | doi: 10.3390/ijms19020608. |
29123258 | Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma. | Br J Cancer | 2018 Jan | Hugdahl E | doi: 10.1038/bjc.2017.384 |
29315289 | MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours. | Br J Cancer | 2018 Jan | Garcia-Dios DA | doi: 10.1038/bjc.2017.450 |
22723415 | Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells. | Science | 2012 Jun 22 | Hoffmeyer K | doi: 10.1126/science.1218370. |
11932355 | Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP. | Jpn J Clin Oncol | 2002 Jan | Nomoto K | - |
21062413 | The human and canine TERT promoters function equivalently in human and canine cells. | Vet Comp Oncol | 2010 Dec | Arendt ML | doi: 10.1111/j.1476-5829.2010.00227.x. |
17991730 | Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development. | FASEB J | 2008 Apr | Moehren U | - |
18037230 | Expression of the full-length telomerase reverse transcriptase (hTERT) transcript in both malignant and normal gastric tissues. | Cancer Lett | 2008 Feb 18 | Li W | - |
20628624 | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot | PLoS Genet | 2010 Jul 8 | Johnatty SE | doi: 10.1371/journal.pgen.1001016. |
19909010 | Growth arrest in ovarian cancer cells by hTERT inhibition short-hairpin RNA targeting human telomerase reverse transcriptase induces immediate growth inhibition but not necessarily induces apoptosis in ovarian cancer cells. | Cancer Invest | 2009 Dec | Luo Y | doi: 10.3109/07357900802491451. |
19877284 | Correlation between morphology and human telomerase gene amplification in bronchial brushing cells for the diagnosis of lung cancer. | Diagn Cytopathol | 2010 Jun | Fan YB | doi: 10.1002/dc.21235. |
21526393 | Serum human telomerase reverse transcriptase: a novel biomarker for breast cancer diagnosis. | Int J Clin Oncol | 2011 Dec | Porika M | doi: 10.1007/s10147-011-0230-6 |
21911295 | Accuracy of telomerase in estimating breast cancer risk: a systematic review and meta-analysis. | Breast | 2012 Feb | Winnikow EP | doi: 10.1016/j.breast.2011.08.136 |
19430894 | Telomerase downregulation in cancer brain stem cell. | Mol Cell Biochem | 2009 Nov | Shervington A | doi: 10.1007/s11010-009-0153-y |
26143634 | The C228T mutation of TERT promoter frequently occurs in bladder cancer stem cells and contributes to tumorigenesis of bladder cancer. | Oncotarget | 2015 Aug 14 | Li C | - |
25716168 | Telomere reverse transcriptase (TERT) rs2735940 increases cancer risk. | Med Sci Monit | 2015 Feb 26 | Yang H | doi: 10.12659/MSM.893087. |
23359026 | The genetic variant rs401681C/T is associated with the risk of non-small cell lung cancer in a Chinese mainland population. | Genet Mol Res | 2013 Jan 22 | Wang H | doi: 10.4238/2013.January.22.5. |
23603989 | Highly prevalent TERT promoter mutations in bladder cancer and glioblastoma. | Cell Cycle | 2013 May 15 | Liu X | doi: 10.4161/cc.24662 |
25680408 | Epidermal growth factor activates telomerase activity by direct binding of Ets-2 to hTERT promoter in lung cancer cells. | Tumour Biol | 2015 Jul | Hsu CP | doi: 10.1007/s13277-015-3204-x |
25151968 | hTERT mediates norepinephrine-induced Slug expression and ovarian cancer aggressiveness. | Oncogene | 2015 Jun | Choi MJ | doi: 10.1038/onc.2014.270 |
12632490 | Relationship between the expression of human telomerase reverse transcriptase gene and cell cycle regulators in gastric cancer and its significance. | World J Gastroenterol | 2003 Mar | Shao JC | - |
22110753 | Twisted epithelial-to-mesenchymal transition promotes progression of surviving bladder cancer T24 cells with hTERT-dysfunction. | PLoS One | 2011 | Xue Y | doi: 10.1371/journal.pone.0027748 |
19224688 | [Expression of hTERT and Mad1 in lung cancer in Gejiu and Xuanwei of Yunnan Province]. | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | 2009 Jan | Cheng JL | - |
28813465 | Long-term persistent infection of HPV 16 E6 up-regulate SP1 and hTERT by inhibiting LKB1 in lung cancer cells. | PLoS One | 2017 Aug 16 | Yang JH | doi: 10.1371/journal.pone.0182775 |
27142689 | GRIM-19 Restores Cervical Cancer Cell Senescence by Repressing hTERT Transcription. | J Interferon Cytokine Res | 2016 Aug | Zhou Y | doi: 10.1089/jir.2015.0125 |
29141053 | Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer. | Acta Biochim Pol | 2017 | Zalewska-Ziob M | doi: 10.18388/abp.2017_1618 |
28627695 | Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo. | Int J Oncol | 2017 Aug | Zheng J | doi: 10.3892/ijo.2017.4040 |
26259389 | Role of telomerase in anticancer activity of pristimerin in prostate cancer cells. | J Exp Ther Oncol | 2015 | Liu YB | - |
22226966 | The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly. | Biochem Biophys Res Commun | 2012 Jan 20 | Her J | doi: 10.1016/j.bbrc.2011.12.101 |
26799744 | Clinical Characteristics and Prognostic Significance of TERT Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis. | PLoS One | 2016 Jan 22 | Yuan P | doi: 10.1371/journal.pone.0146803 |
12119560 | Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer. | Int J Mol Med | 2002 Aug | Kanamaru T | - |
23527617 | Implications of telomere-independent activities of telomerase reverse transcriptase in human cancer. | FEBS J | 2013 Jul | Ding D | doi: 10.1111/febs.12258 |
12529350 | Retinoic acid receptor beta and telomerase catalytic subunit expression in bronchial epithelium of heavy smokers. | J Natl Cancer Inst | 2003 Jan 15 | Soria JC | - |
25296732 | TERT polymorphisms rs2853669 and rs7726159 influence on prostate cancer risk in Russian population. | Tumour Biol | 2015 Feb | Shadrina AS | doi: 10.1007/s13277-014-2688-0 |
21771723 | Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. | Carcinogenesis | 2011 Oct | Pande M | doi: 10.1093/carcin/bgr136 |
23899579 | Telomerase as a potential marker for inflammation and cancer detection in bronchial washing: a prospective study. | Clin Biochem | 2013 Nov | Nassani N | doi: 10.1016/j.clinbiochem.2013.07.018 |
17644806 | High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection. | Reprod Sci | 2007 May | Wang PH | - |
15477760 | Genomic instability is associated with lack of telomerase activation in ovarian cancer. | Cancer Biol Ther | 2004 Dec | Landen CN | - |
23535824 | Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. | Hum Mol Genet | 2013 Jun 15 | Kote-Jarai Z | doi: 10.1093/hmg/ddt086 |
19501078 | Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ transcript in estrogen receptor-positive MCF-7 breast cancer cells. | Clin Biochem | 2009 Sep | Strati A | doi: 10.1016/j.clinbiochem.2009.05.017 |
23244087 | Association of TERT rs2736098 polymorphism with cancer risk: a meta-analysis. | Asian Pac J Cancer Prev | 2012 | Zhang XJ | - |
12843187 | Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells. | J Clin Endocrinol Metab | 2003 Jul | Wetterau LA | - |
21949400 | Separation of telomerase functions by reverse genetics. | Proc Natl Acad Sci U S A | 2011 Dec 13 | Mukherjee S | doi: 10.1073/pnas.1112414108 |
23226346 | TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications. | PLoS One | 2012 | Yin J | doi: 10.1371/journal.pone.0050650 |
23284306 | A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. | PLoS Genet | 2012 | Xie L | doi: 10.1371/journal.pgen.1003151 |
23158658 | [Leptin promotes the expression of hTERT via STAT3 in breast cancer cells]. | Zhonghua Yi Xue Za Zhi | 2012 Sep 11 | Li SS | - |
24086482 | Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells. | PLoS One | 2013 Sep 25 | Mazumdar T | doi: 10.1371/journal.pone.0075253 |
15788678 | Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. | Clin Cancer Res | 2005 Mar 15 | Ohuchida K | - |
14646192 | Adenovirus-mediated suicide gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter induced apoptosis of ovarian cancer cell line. | Biosci Biotechnol Biochem | 2003 Nov | Song JS | - |
25586649 | A LINE-1-encoded reverse transcriptase-dependent regulatory mechanism is active in embryogenesis and tumorigenesis. | Ann N Y Acad Sci | 2015 Apr | Spadafora C | doi: 10.1111/nyas.12637 |
24914385 | Telomerase and hTERT: can they serve as markers for gastric cancer diagnosis? | World J Gastroenterol | 2014 Jun 7 | Cheng YB | doi: 10.3748/wjg.v20.i21.6615. |
23065203 | HTERT MNS16A polymorphism in breast cancer: a case-control study. | Mol Biol Rep | 2012 Dec | Zagouri F | doi: 10.1007/s11033-012-1982-4 |
26149460 | TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer. | Clin Cancer Res | 2015 Nov 15 | Wei R | doi: 10.1158/1078-0432.CCR-15-0009 |
12508351 | Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation. | World J Gastroenterol | 2003 Jan | Lan J | - |
12937127 | Significance of immunological detection of human telomerase reverse transcriptase: re-evaluation of expression and localization of human telomerase reverse transcriptase. | Am J Pathol | 2003 Sep | Kyo S | - |
24583168 | The absence of TERT promoter mutations in primary gastric cancer. | Gene | 2014 May 1 | Liu T | doi: 10.1016/j.gene.2014.02.051 |
24216762 | An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells. | Mol Cell Biol | 2014 Jan | Listerman I | doi: 10.1128/MCB.00844-13 |
16810748 | Inhibitory effects of antisense phosphorothioate oligodeoxynucleotides on pancreatic cancer cell Bxpc-3 telomerase activity and cell growth in vitro. | World J Gastroenterol | 2006 Jul 7 | Wang YF | - |
21763315 | RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer. | FEBS Lett | 2011 Aug 4 | Flavin P | doi: 10.1016/j.febslet.2011.07.005 |
21614210 | Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle. | Int J Mol Sci | 2010 | Duangmano S | doi: 10.3390/ijms11125323 |
19380022 | A functional promoter polymorphism in the TERT gene does not affect inherited susceptibility to breast cancer. | Cancer Genet Cytogenet | 2009 Apr 15 | Varadi V | doi: 10.1016/j.cancergencyto.2008.12.006. |
26004560 | Pro-apoptotic and anti-proliferative effects of 3,3'-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity. | Mol Med Rep | 2015 Sep | Li F | doi: 10.3892/mmr.2015.3836 |
16008894 | [Expression of human telomerase reverse transcriptase in cervix cancer and its significance]. | Zhonghua Fu Chan Ke Za Zhi | 2005 Jun | Xi L | - |
21082235 | Identification of CD133(-)/telomerase(low) progenitor cells in glioblastoma-derived cancer stem cell lines. | Cell Mol Neurobiol | 2011 Apr | Beier F | doi: 10.1007/s10571-010-9627-4 |
20545697 | Alternative lengthening of telomeres in hTERT-inhibited laryngeal cancer cells. | Cancer Sci | 2010 Aug | Chen W | doi: 10.1111/j.1349-7006.2010.01611.x |
19787269 | The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells. | Int J Oncol | 2009 Nov | Papanikolaou V | - |
22757972 | hTERT-siRNA could potentiate the cytotoxic effect of gemcitabine to pancreatic cancer cells Bxpc-3. | Exp Clin Transplant | 2012 Aug | Tan J | doi: 10.6002/ect.2011.0157 |
26913901 | Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer. | PLoS One | 2016 Feb 25 | Fern??ndez-Marcelo T | doi: 10.1371/journal.pone.0149626 |
23677713 | Telomerase downregulation induces proapoptotic genes expression and initializes breast cancer cells apoptosis followed by DNA fragmentation in a cell type dependent manner. | Mol Biol Rep | 2013 Aug | Rubis B | doi: 10.1007/s11033-013-2600-9 |
24993489 | Ferrocenylnaphthalene diimide-based electrochemical detection of aberrant methylation in hTERT gene. | Appl Biochem Biotechnol | 2014 Oct | Sato S | doi: 10.1007/s12010-014-1030-z |
21575461 | [Prognostic significance of hTERT mRNA quantitative expression in resected gastric carcinomas]. | Zhonghua Zhong Liu Za Zhi | 2011 Jan | Qiu D | - |
24535778 | TERT rs2736100 polymorphism contributes to lung cancer risk: a meta-analysis including 49,869 cases and 73,464 controls. | Tumour Biol | 2014 Jun | Nie W | doi: 10.1007/s13277-014-1734-2 |
15053304 | Telomerase expression as a marker in prostate cancer: correlation to clinicopathologic predictors. | J Exp Clin Cancer Res | 2003 Dec | Athanassiadou P | - |
21638208 | Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and cancer cells of various origins. | Cell Tissue Res | 2011 Jul | Jeon BG | doi: 10.1007/s00441-011-1191-9 |
16786150 | Specific subtelomere loss on chromosome der(11)t(3;11)(q23;q23)x2 in anaplastic thyroid cancer cell line OCUT-1. | Int J Mol Med | 2006 Jul | Kammori M | - |
18038311 | Real-time PCR quantification of human telomerase reverse transcriptase (hTERT) in colorectal cancer. | Pathology | 2008 Jan | Saleh S | - |
22267287 | Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk. | Cancer Epidemiol Biomarkers Prev | 2012 Mar | Terry KL | doi: 10.1158/1055-9965.EPI-11-0867 |
24174344 | CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: identification of a novel enhancer region involved in the regulation of TERT gene. | Int J Cancer | 2014 May 15 | Eldholm V | doi: 10.1002/ijc.28570 |
26519755 | Human telomerase reverse transcriptase (hTERT) promotes cancer invasion by modulating cathepsin D via early growth response (EGR)-1. | Cancer Lett | 2016 Jan 28 | Park YJ | doi: 10.1016/j.canlet.2015.10.021 |
20659312 | Short rare hTERT-VNTR2-2nd alleles are associated with prostate cancer susceptibility and influence gene expression. | BMC Cancer | 2010 Jul 26 | Yoon SL | doi: 10.1186/1471-2407-10-393. |
25940397 | TERT gene harbors multiple variants associated with pancreatic cancer susceptibility. | Int J Cancer | 2015 Nov 1 | Campa D | doi: 10.1002/ijc.29590 |
25121551 | Diagnostic and prognostic TERT promoter mutations in thyroid fine-needle aspiration biopsy. | Endocr Relat Cancer | 2014 Oct | Liu R | doi: 10.1530/ERC-14-0359 |
22037553 | A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. | Nat Genet | 2011 Oct 30 | Haiman CA | doi: 10.1038/ng.985. |
18978790 | Lung cancer susceptibility locus at 5p15.33. | Nat Genet | 2008 Dec | McKay JD | doi: 10.1038/ng.254 |
25098685 | Inhibition of telomerase activity by dominant-negative hTERT retards the growth of breast cancer cells. | Breast Cancer | 2016 Mar | Rao Y | doi: 10.1007/s12282-014-0553-z |
25662441 | miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT. | Cancer Lett | 2015 May 1 | Zhang D | doi: 10.1016/j.canlet.2015.01.044 |
26318425 | RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth. | Oncotarget | 2015 Sep 29 | Qin Y | doi: 10.18632/oncotarget.4825. |
19955392 | Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers. | Carcinogenesis | 2010 Feb | Wang Y | doi: 10.1093/carcin/bgp287 |
21071633 | hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells. | Cancer Res | 2011 Jan 1 | Indran IR | doi: 10.1158/0008-5472.CAN-10-1588 |
23707794 | Genetic variants in TERT-CLPTM1L genetic region associated with several types of cancer: a meta-analysis. | Gene | 2013 Sep 10 | Li C | doi: 10.1016/j.gene.2013.05.003 |
23741361 | Inhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity. | PLoS One | 2013 May 31 | Wang W | doi: 10.1371/journal.pone.0064660 |
12135483 | Differential regulation of telomerase activity by six telomerase subunits. | Eur J Biochem | 2002 Jul | Chang JT | - |
24285288 | Low frequency of TERT promoter mutations in a large cohort of gallbladder and gastric cancers. | Int J Cancer | 2014 Jun 15 | Qu Y | doi: 10.1002/ijc.28633 |
25966219 | Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population. | Genet Mol Res | 2015 May 4 | Liu SG | doi: 10.4238/2015.May.4.4. |
26428673 | Resveratrol attenuates norepinephrine-induced ovarian cancer invasiveness through downregulating hTERT expression. | Arch Pharm Res | 2016 Feb | Kim SH | doi: 10.1007/s12272-015-0666-8 |
17960465 | Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas. | J Gastrointest Surg | 2008 Jan | Hashimoto Y | - |
11940318 | [Inhibition of telomerase activity and induction of apoptosis in lung cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide]. | Zhonghua Nei Ke Za Zhi | 2002 Mar | Wang X | - |
11916966 | A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer. | J Biol Chem | 2002 Jun 7 | Li H | - |
27016301 | Polymorphisms in human telomerase reverse transcriptase (hTERT) gene and susceptibility to gastric cancer in a Turkish population: Hospital-based case-control study. | Gene | 2016 Jul 1 | Bayram S | doi: 10.1016/j.gene.2016.03.030 |
15545228 | Emerging role of p53, bcl-2 and telomerase activity in Egyptian breast cancer patients. | IUBMB Life | 2004 Aug | Swellam M | - |
20478107 | Variation at the TERT locus and predisposition for cancer. | Expert Rev Mol Med | 2010 May 18 | Baird DM | doi: 10.1017/S146239941000147X. |
23799592 | Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro. | Oncol Rep | 2013 Sep | Chen PC | doi: 10.3892/or.2013.2563 |
25448848 | Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization. | Mol Cell Endocrinol | 2015 Jan 5 | Muzza M | doi: 10.1016/j.mce.2014.10.019 |
23908149 | Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population. | Mol Carcinog | 2013 Nov | Zhong R | doi: 10.1002/mc.22043 |
24030752 | Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma. | Mod Pathol | 2014 Apr | Scott GA | doi: 10.1038/modpathol.2013.167 |
20570912 | No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk. | Cancer Epidemiol Biomarkers Prev | 2010 Jul | Pooley KA | doi: 10.1158/1055-9965.EPI-10-0281 |
16525654 | Alteration of hTERT full-length variant expression level showed different gene expression profiles and genomic copy number changes in breast cancer. | Oncol Rep | 2006 Apr | Rha SY | - |
26540342 | An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer. | Oncotarget | 2016 Jan 5 | Qin Y | doi: 10.18632/oncotarget.5968. |
21045143 | Telomerase-dependent oncolytic adenovirus sensitizes human cancer cells to ionizing radiation via inhibition of DNA repair machinery. | Cancer Res | 2010 Nov 15 | Kuroda S | doi: 10.1158/0008-5472.CAN-10-2333 |
15900578 | Quantitative evaluation of telomerase subunits in urine as biomarkers for noninvasive detection of bladder cancer. | Int J Cancer | 2005 Nov 1 | Weikert S | - |
23933091 | Physiological and pathological significance of human telomerase reverse transcriptase splice variants. | Biochimie | 2013 Nov | Bollmann FM | doi: 10.1016/j.biochi.2013.07.031 |
16734859 | Real-time quantitative analysis for human telomerase reverse transcriptase mRNA and human telomerase RNA component mRNA expressions as markers for clinicopathologic parameters in urinary bladder cancer. | Int J Urol | 2006 Apr | Takihana Y | - |
24973886 | Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line. | Mol Biol Rep | 2014 Sep | Rahmati-Yamchi M | doi: 10.1007/s11033-014-3505-y |
18380945 | Effects of telomerase activity on carcinogenesis and survival in laryngeal carcinoma. | J Int Med Res | 2008 Mar-Apr | Chen M | - |
24283584 | TERT genetic polymorphism rs2736100 was associated with lung cancer: a meta-analysis based on 14,492 subjects. | Genet Test Mol Biomarkers | 2013 Dec | Wang HM | doi: 10.1089/gtmb.2013.0322. |
11788906 | Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome. | Int J Oncol | 2002 Feb | Mueller C | - |
26020272 | Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients. | PLoS One | 2015 May 28 | Zhao X | doi: 10.1371/journal.pone.0129232 |
24742867 | TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomas. | Oncotarget | 2014 Apr 15 | Wang K | - |
19194757 | Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer. | Ann Surg Oncol | 2009 Apr | Kumari A | doi: 10.1245/s10434-009-0333-8 |
22125638 | Pancreatic cancer susceptibility loci and their role in survival. | PLoS One | 2011 | Rizzato C | doi: 10.1371/journal.pone.0027921 |
21106093 | Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts. | BMC Cancer | 2010 Nov 24 | Brems-Eskildsen AS | doi: 10.1186/1471-2407-10-646. |
22134622 | Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry. | Breast Cancer Res Treat | 2012 Feb | Zheng Y | doi: 10.1007/s10549-011-1890-7 |
26458818 | Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines. | Biochem Cell Biol | 2016 Feb | Abbas A | doi: 10.1139/bcb-2015-0038 |
24390616 | Association between TERT rs2736100 polymorphism and lung cancer susceptibility: evidence from 22 case-control studies. | Tumour Biol | 2014 May | Yuan Y | doi: 10.1007/s13277-013-1583-4 |
20920335 | Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer. | BMC Urol | 2010 Oct 4 | Mezzasoma L | doi: 10.1186/1471-2490-10-17. |
26969876 | Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM staging system in differentiated thyroid cancer patients. | Cancer | 2016 May 1 | Song YS | doi: 10.1002/cncr.29934 |
24861918 | Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population. | Med Oncol | 2014 Jul | Zhang Y | doi: 10.1007/s12032-014-0018-4 |
20225759 | Changes of telomerase activity by alternative splicing of full-length and beta variants of hTERT in breast cancer patients. | Oncol Res | 2009 | Rha SY | - |
17177836 | Telomerase antisense inhibition for the proliferation of endometrial cancer in vitro and in vivo. | Int J Gynecol Cancer | 2006 Nov-Dec | Chen XJ | - |
20520826 | Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stress. | PLoS One | 2010 May 25 | Kovalenko OA | doi: 10.1371/journal.pone.0010812. |
18562689 | Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. | Mol Biol Cell | 2008 Sep | Tomlinson RL | doi: 10.1091/mbc.E08-02-0184 |
19151717 | Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. | Nat Genet | 2009 Feb | Rafnar T | doi: 10.1038/ng.296 |
20543847 | Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. | Nat Genet | 2010 Jul | Turnbull C | doi: 10.1038/ng.607 |
16490880 | Inhibition of human telomerase reverse transcriptase in hep-2 cells using short hairpin RNA expression vectors. | Arch Otolaryngol Head Neck Surg | 2006 Feb | Chen SM | - |
27461695 | Polymorphisms in the telomerase reverse transcriptase promoter are associated with risk of breast cancer: A meta-analysis. | J Cancer Res Ther | 2016 Apr-Jun | Li ZY | doi: 10.4103/0973-1482.164701. |
26042809 | Association between the TERT Genetic Polymorphism rs2853676 and Cancer Risk: Meta-Analysis of 76,108 Cases and 134,215 Controls. | PLoS One | 2015 Jun 4 | Cao JL | doi: 10.1371/journal.pone.0128829 |
19955841 | Phosphorylation status of Fas-associated death domain-containing protein regulates telomerase activity and strongly correlates with prostate cancer outcomes. | Pathobiology | 2009 | Matsumura Y | doi: 10.1159/000245895 |
24260099 | Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: evidence from a case-control study of non-small-cell lung cancer and a meta-analysis. | PLoS One | 2013 Nov 19 | Wu H | doi: 10.1371/journal.pone.0076372 |
25722414 | Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer. | Science | 2015 Feb 27 | Borah S | doi: 10.1126/science.1260200 |
20629177 | Kr??ppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells. | Stem Cells | 2010 Sep | Wong CW | doi: 10.1002/stem.477. |
20466886 | A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer. | Clin Cancer Res | 2010 Jul 15 | Wang L | doi: 10.1158/1078-0432.CCR-10-0269 |
25254308 | Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population. | Eur J Cancer Prev | 2014 Nov | Gao L | doi: 10.1097/CEJ.0000000000000086. |
17487429 | Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma. | Int J Mol Med | 2007 Jun | Tang WK | - |
21042751 | Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth. | Oncol Rep | 2010 Dec | Xue Y | - |
24067943 | Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer. | Oncol Rep | 2013 Dec | Antoniou KM | doi: 10.3892/or.2013.2753 |
22228261 | Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population. | Mol Carcinog | 2012 Oct | Wang S | doi: 10.1002/mc.21872 |
14688476 | Haploinsufficiency of hTERT leads to telomere dysfunction and radiosensitivity in human cancer cells. | Cancer Biol Ther | 2003 Nov-Dec | Hauguel T | - |
18836306 | Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach. | Cancer Biol Ther | 2008 Nov | Xing Y | - |
23519253 | Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer. | Molecules | 2012 Dec 11 | Liu Y | doi: 10.3390/molecules171214795. |
20056641 | Multiple genetic variants in telomere pathway genes and breast cancer risk. | Cancer Epidemiol Biomarkers Prev | 2010 Jan | Shen J | doi: 10.1158/1055-9965.EPI-09-0771. |
21411498 | A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells. | Cancer Prev Res (Phila) | 2011 Aug | Meeran SM | doi: 10.1158/1940-6207.CAPR-11-0009 |
24436132 | TERT promoter mutations predict worse survival in laryngeal cancer patients. | Int J Cancer | 2014 Aug 15 | Qu Y | doi: 10.1002/ijc.28728 |
20456367 | Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development. | Cancer Sci | 2010 Jul | Waki K | doi: 10.1111/j.1349-7006.2010.01576.x |
24577890 | Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population. | Tumour Biol | 2014 Jun | Liu C | doi: 10.1007/s13277-014-1711-9 |
26053551 | A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase. | PLoS Genet | 2015 Jun 8 | Killedar A | doi: 10.1371/journal.pgen.1005286 |
18438345 | Correlations of BMI-1 expression and telomerase activity in ovarian cancer tissues. | Exp Oncol | 2008 Mar | Zhang F | - |
25433838 | Amplification of TERT and TERC genes in cervical intraepithelial neoplasia and cervical cancer. | Neuro Endocrinol Lett | 2014 | Visnovsky J | - |
25487306 | Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. | Hum Genet | 2015 Feb | Carvajal-Carmona LG | doi: 10.1007/s00439-014-1515-4 |
20127252 | BRCA1 is a negative modulator of the PRC2 complex. | EMBO J | 2013 May 29 | Wang L | doi: 10.1038/emboj.2013.95 |
17462602 | A novel peptide-nucleotide dual vaccine of human telomerase reverse transcriptase induces a potent cytotoxic T-cell response in vivo. | Biochem Biophys Res Commun | 2007 Jun 15 | Guo H | - |
16641908 | Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. | Br J Cancer | 2006 May 22 | Zhu CQ | - |
20146105 | Prognostic significance of telomerase activity and some tumor markers in non-small cell lung cancer. | Med Oncol | 2011 Mar | Hashim M | doi: 10.1007/s12032-010-9444-0 |
18820283 | Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells. | Carcinogenesis | 2008 Dec | Kim RH | doi: 10.1093/carcin/bgn225 |
22351525 | TERT's role in colorectal carcinogenesis. | Mol Carcinog | 2013 Jul | Pellatt AJ | doi: 10.1002/mc.21885 |
22495810 | Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk. | Mol Carcinog | 2012 Oct | Hofer P | doi: 10.1002/mc.21911 |
18952593 | Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells. | Carcinogenesis | 2009 Jan | Chatagnon A | doi: 10.1093/carcin/bgn240 |
25809917 | Mutations in TERT promoter and FGFR3 and telomere length in bladder cancer. | Int J Cancer | 2015 Oct 1 | Hosen I | doi: 10.1002/ijc.29526 |
19903789 | Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase. | Clin Cancer Res | 2009 Nov 15 | Mai W | doi: 10.1158/1078-0432.CCR-09-0973 |
19559675 | Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity. | Biochem Biophys Res Commun | 2009 Sep 4 | Zhou L | doi: 10.1016/j.bbrc.2009.06.116 |
27455559 | [THE SOMATIC MUTATIONS AND ABERRANT METHYLATION AS POTENTIAL GENETIC MARKERS OF URINARY BLADDER CANCER]. | Klin Lab Diagn | 2016 Feb | Mikhailenko DS | - |
23433592 | Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer--a case-control study in a Chinese population. | Lung Cancer | 2013 May | Myneni AA | doi: 10.1016/j.lungcan.2013.01.021 |
26766154 | [Determination of CEA, EGFR and hTERT expression in peritoneal lavage in patients with pancreatic adenocarcinoma using RT - PCR method]. | Rozhl Chir | 2015 Nov | Ghothim M | - |
16135795 | Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. | Mol Cell Biol | 2005 Sep | Takakura M | - |
24481448 | miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase. | Cell Death Dis | 2014 Jan 30 | Chen L | doi: 10.1038/cddis.2013.553. |
18664542 | Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in the blood of familial papillary thyroid cancer patients. | J Clin Endocrinol Metab | 2008 Oct | Capezzone M | doi: 10.1210/jc.2008-0372 |
17630431 | Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells. | J Biol Chem | 2007 Sep 7 | Deng WG | - |
19214569 | Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy. | J Cancer Res Clin Oncol | 2009 Sep | Zachos I | doi: 10.1007/s00432-009-0557-9 |
25574106 | Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations. | World J Gastroenterol | 2015 Jan 7 | Cevik D | doi: 10.3748/wjg.v21.i1.311. |
23901064 | Genetic variants at 5p15 are associated with risk and early onset of gastric cancer in Chinese populations. | Carcinogenesis | 2013 Nov | Du J | doi: 10.1093/carcin/bgt259 |
24386361 | Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma. | PLoS One | 2013 Dec 30 | Jiang M | doi: 10.1371/journal.pone.0084277 |
14612409 | BRCA1 inhibition of telomerase activity in cultured cells. | Mol Cell Biol | 2003 Dec | Xiong J | - |
20423850 | [Effect of hTERT antisense oligodeoxynucleotide on telomerase activity in bladder cancer cells in vitro]. | Nan Fang Yi Ke Da Xue Xue Bao | 2010 Apr | Gao XD | - |
23221128 | Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. | Cancer Epidemiol Biomarkers Prev | 2013 Feb | Walsh KM | doi: 10.1158/1055-9965.EPI-12-1007-T |
23993966 | Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer. | Cell Signal | 2013 Dec | Wu XQ | doi: 10.1016/j.cellsig.2013.08.009 |
12765058 | [Detection of telomerase activity by semi-quantitative and in situ assays and quantification of hTERT expression in bladder carcinomas]. | Prog Urol | 2003 Apr | Longchampt E | - |
21353795 | Telomerase mRNA detection in serum of patients with prostate cancer. | Urol Oncol | 2013 Feb | Dalle Carbonare L | doi: 10.1016/j.urolonc.2010.12.017 |
25194236 | Analysis of telomerase activity based on a spired DNA tetrahedron TS primer. | Biosens Bioelectron | 2015 May 15 | Li Y | doi: 10.1016/j.bios.2014.08.056 |
27472887 | hTERT gene polymorphism correlates with the risk and the prognosis of thyroid cancer. | Cancer Biomark | 2016 Jul 8 | Gong L | doi: 10.3233/CBM-160631. |
23462332 | The TERT MNS16A polymorphism contributes to cancer susceptibility: meta-analysis of the current studies. | Gene | 2013 May 1 | Chen P | doi: 10.1016/j.gene.2013.02.018 |
26309358 | Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer. | World J Gastroenterol | 2015 Aug 21 | Choi BJ | doi: 10.3748/wjg.v21.i31.9328. |
23933993 | Silencing tankyrase and telomerase promotes A549 human lung adenocarcinoma cell apoptosis and inhibits proliferation. | Oncol Rep | 2013 Oct | Lu H | doi: 10.3892/or.2013.2665 |
23368278 | Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population. | Exp Lung Res | 2013 Mar | Zhao Z | doi: 10.3109/01902148.2012.762436 |
27229911 | The potential of identification of a malignancy-associated biomarker in breast cancer diagnosis and research: hTERT gene DNA methylation. | Diagn Cytopathol | 2016 Aug | Masood S | doi: 10.1002/dc.23505 |
22872929 | Bmi-1 siRNA inhibited ovarian cancer cell line growth and decreased telomerase activity. | Br J Biomed Sci | 2012 | Xin T | - |
24528514 | Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity. | J Exp Clin Cancer Res | 2014 Feb 15 | Fern??ndez-Marcelo T | doi: 10.1186/1756-9966-33-19. |
26261549 | Effects of targeted nano-delivery systems combined with hTERT-siRNA and Bmi-1-siRNA on MCF-7 cells. | Int J Clin Exp Pathol | 2015 Jun 1 | Liu L | - |
19414359 | Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer. | Anticancer Res | 2009 Apr | Metzger R | - |
20565943 | Irradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population. | BMC Cancer | 2010 Jun 21 | He X | doi: 10.1186/1471-2407-10-312. |
21422235 | MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer. | Carcinogenesis | 2011 Jun | Hofer P | doi: 10.1093/carcin/bgr053 |
25037574 | Genetic polymorphisms of TERT and CLPTM1L, cooking oil fume exposure, and risk of lung cancer: a case-control study in a Chinese non-smoking female population. | Med Oncol | 2014 Aug | Yin Z | doi: 10.1007/s12032-014-0114-5 |
15112354 | Detection of K-ras point mutation and telomerase activity during endoscopic retrograde cholangiopancreatography in diagnosis of pancreatic cancer. | World J Gastroenterol | 2004 May 1 | Zhou GX | - |
21590772 | Activation of telomerase by seminal plasma in malignant and normal cervical epithelial cells. | J Pathol | 2011 Oct | Liu L | doi: 10.1002/path.2914 |
26733501 | TERT promoter mutations in thyroid cancer. | Endocr Relat Cancer | 2016 Mar | Liu R | doi: 10.1530/ERC-15-0533 |
23629941 | Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. | Genes Chromosomes Cancer | 2013 Jul | Pellatt AJ | doi: 10.1002/gcc.22056 |
27273963 | New evidence of TERT rs2736098 polymorphism and cancer risk: an updated meta-analysis. | J BUON | 2016 Mar-Apr | Li T | - |
12753708 | [Relationship between human telomerase reverse transcriptase transcriptional level and telomerase activity in three ovarian cancer cell lines]. | Ai Zheng | 2003 May | Song Y | - |
23535731 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. | Nat Genet | 2013 Apr | Bojesen SE | doi: 10.1038/ng.2566. |
24018021 | Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome. | Eur Urol | 2014 Feb | Allory Y | doi: 10.1016/j.eururo.2013.08.052 |
20534141 | hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis. | BMC Cancer | 2010 Jun 9 | de Wilde J | doi: 10.1186/1471-2407-10-271. |
23555636 | Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. | PLoS One | 2013 | Lan Q | doi: 10.1371/journal.pone.0059230 |
21622582 | The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema. | Eur Respir J | 2011 Oct | Wauters E | doi: 10.1183/09031936.00187110 |
23045275 | Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. | Oncogene | 2013 Sep 5 | Liu Z | doi: 10.1038/onc.2012.441 |
24121487 | TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine. | Cancer Res | 2013 Dec 15 | Kinde I | doi: 10.1158/0008-5472.CAN-13-2498 |
24260374 | TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma. | PLoS One | 2013 Nov 18 | Griewank KG | doi: 10.1371/journal.pone.0080354 |
23738012 | Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in Chinese women nonsmokers. | PLoS One | 2013 May 30 | Li C | doi: 10.1371/journal.pone.0064988 |
23432846 | Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer. | Diagn Pathol | 2013 Feb 22 | Wang L | doi: 10.1186/1746-1596-8-33. |
22221621 | The TERT rs2736100 polymorphism and cancer risk: a meta-analysis based on 25 case-control studies. | BMC Cancer | 2012 Jan 5 | Zou P | doi: 10.1186/1471-2407-12-7. |
23055531 | 1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498. | J Biol Chem | 2012 Nov 30 | Kasiappan R | doi: 10.1074/jbc.M112.407189 |
26425038 | TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population. | J Korean Med Sci | 2015 Oct | Yoo SS | doi: 10.3346/jkms.2015.30.10.1423 |
18063440 | Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival. | Lung Cancer | 2008 Jul | Targowski T | - |
25873431 | Acidified bile acids increase hTERT expression via c-myc activation in human gastric cancer cells. | Oncol Rep | 2015 Jun | Wang X | doi: 10.3892/or.2015.3908 |
21453684 | Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo. | Biochem Pharmacol | 2011 Jul 1 | Liu X | doi: 10.1016/j.bcp.2011.03.017 |
23454887 | Role of selected genetic variants in lung cancer risk in African Americans. | J Thorac Oncol | 2013 Apr | Spitz MR | doi: 10.1097/JTO.0b013e318283da29. |
26903137 | hTERT mediates gastric cancer metastasis partially through the indirect targeting of ITGB1 by microRNA-29a. | Sci Rep | 2016 Feb 23 | He B | doi: 10.1038/srep21955. |
18586674 | Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc. | J Biol Chem | 2008 Aug 29 | Xu D | doi: 10.1074/jbc.M800790200 |
19375219 | Radiation enhances suicide gene therapy in radioresistant laryngeal squamous cell carcinoma via activation of a tumor-specific promoter. | Cancer Lett | 2009 Sep 28 | Liao Z | doi: 10.1016/j.canlet.2009.03.021 |
26194807 | Cancer-associated TERT promoter mutations abrogate telomerase silencing. | Elife | 2015 Jul 21 | Chiba K | doi: 10.7554/eLife.07918. |
26472030 | Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells. | Oncotarget | 2015 Nov 10 | Ci X | doi: 10.18632/oncotarget.5752. |
25481043 | Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells. | Oncotarget | 2014 Dec 15 | Chen W | - |
24761905 | Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in a Chinese population. | Asian Pac J Cancer Prev | 2014 | Zhao MM | - |
25843513 | Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation. | Eur J Cancer | 2015 May | Huang DS | doi: 10.1016/j.ejca.2015.03.010 |
19272297 | Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis. | Clin Biochem | 2009 Jun | Shaker OG | doi: 10.1016/j.clinbiochem.2008.12.025 |
26501986 | Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer. | Genet Test Mol Biomarkers | 2015 Dec | Jannuzzi AT | doi: 10.1089/gtmb.2015.0150 |
16979586 | Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCalpha. | Biochem Biophys Res Commun | 2006 Nov 3 | Jagadeesh S | - |
24590268 | Increased lung cancer risk associated with the TERT rs2736100 polymorphism: an updated meta-analysis. | Tumour Biol | 2014 Jun | Yang J | doi: 10.1007/s13277-014-1765-8 |
22994782 | TERT rs2736098 polymorphism and cancer risk: results of a meta-analysis. | Asian Pac J Cancer Prev | 2012 | Qi HY | - |
21627565 | hTERT regulation by NF-??B and c-myc in irradiated HER2-positive breast cancer cells. | Int J Radiat Biol | 2011 Jun | Papanikolaou V | doi: 10.3109/09553002.2011.572112. |
18223679 | TERT promotes cellular and organismal survival independently of telomerase activity. | Oncogene | 2008 Jun 12 | Lee J | doi: 10.1038/sj.onc.1211037 |
26823830 | Expression of phosphorylated Akt and hTERT is associated with prognosis of epithelial ovarian carcinoma. | Int J Clin Exp Pathol | 2015 Nov 1 | Lee YK | - |
22108635 | Hypomethylated CpG around the transcription start site enables TERT expression and HPV16 E6 regulates TERT methylation in cervical cancer cells. | Gynecol Oncol | 2012 Mar | Jiang J | doi: 10.1016/j.ygyno.2011.11.023 |
18414191 | Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro. | Eur J Cancer Prev | 2008 Jun | Yang SM | doi: 10.1097/CEJ.0b013e3282b71f0d. |
23690220 | Differences in the expression of telomerase and prostate-specific membrane antigen in non-advanced prostatic cancer. | Folia Histochem Cytobiol | 2013 | Gasinska A | doi: 10.5603/FHC.2013.0010. |
25775949 | Synthetic miRNA sponges driven by mutant hTERT promoter selectively inhibit the progression of bladder cancer. | Tumour Biol | 2015 Jul | Zhuang CL | doi: 10.1007/s13277-015-3169-9 |
18413362 | A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women. | Carcinogenesis | 2008 Jun | Wang Y | doi: 10.1093/carcin/bgn099 |
15202008 | In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer. | Int J Oncol | 2004 Jul | Amarnath SM | - |
21252717 | Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer. | J Thorac Oncol | 2011 Feb | Sirera R | doi: 10.1097/JTO.0b013e31820189a5. |
25501509 | Polygala tenuifolia polysaccharide (PTP) inhibits cell proliferation by repressing Bmi-1 expression and downregulating telomerase activity. | Tumour Biol | 2015 Apr | Zhang F | doi: 10.1007/s13277-014-2920-y |
23610451 | The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis. | Cancer Res | 2013 May 1 | Listerman I | doi: 10.1158/0008-5472.CAN-12-3082 |
15099954 | Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer. | Gynecol Oncol | 2004 May | Widschwendter A | - |
27120048 | Detection of hTERT mRNA in peripheral blood and its implication for diagnosis of early stage postoperative endometrial cancer micrometastasis. | Panminerva Med | 2016 Sep | Liang J | - |
27420401 | A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. | Int J Cancer | 2016 Dec 15 | Lee AW | doi: 10.1002/ijc.30274 |
27696331 | TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence. | Protein Cell | 2017 Jan | Cassar L | doi: 10.1007/s13238-016-0322-1 |
27892716 | Life and cancer without telomerase: ALT and other strategies for making sure ends (don't) meet. | Crit Rev Biochem Mol Biol | 2017 Feb | Apte MS | doi: 10.1080/10409238.2016.1260090 |
27481844 | Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells. | J Immunol | 2016 Sep 1 | Galaine J | doi: 10.4049/jimmunol.1502633 |
27797938 | Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer. | Gut | 2017 Jun | Bao Y | doi: 10.1136/gutjnl-2016-312510 |
26902827 | TERT Promoter Mutations in Thyroid Cancer. | Horm Cancer | 2016 Jun | Alzahrani AS | doi: 10.1007/s12672-016-0256-3 |
27643433 | Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression. | J Clin Invest | 2016 Oct 3 | Khattar E | doi: 10.1172/JCI86042 |
28423629 | Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population. | Oncotarget | 2017 Mar 21 | Zhang J | doi: 10.18632/oncotarget.15664. |
28766760 | The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis. | APMIS | 2017 Sep | Haraguchi K | doi: 10.1111/apm.12723 |
28364361 | A novel method to generate single-cell-derived cancer-associated fibroblast clones. | J Cancer Res Clin Oncol | 2017 Aug | Hashimoto H | doi: 10.1007/s00432-017-2409-3 |
28335076 | Fine mapping of chromosome 5p15.33 identifies novel lung cancer susceptibility loci in Han Chinese. | Int J Cancer | 2017 Aug 1 | Dong J | doi: 10.1002/ijc.30702 |
28864536 | Changes in the clinicopathological characteristics and genetic alterations of follicular thyroid cancer. | Eur J Endocrinol | 2017 Dec | Song YS | doi: 10.1530/EJE-17-0456 |
29045464 | TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter. | PLoS Pathog | 2017 Oct 18 | Rajagopalan D | doi: 10.1371/journal.ppat.1006681 |
28641311 | Characterisation of blood-derived exosomal hTERT mRNA secretion in cancer patients: a potential pan-cancer marker. | Br J Cancer | 2017 Jul 25 | Goldvaser H | doi: 10.1038/bjc.2017.166 |
28288903 | Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells. | Mol Cell Endocrinol | 2017 Jun 15 | Maggisano V | doi: 10.1016/j.mce.2017.03.007 |
27528624 | TERT promoter mutations and long-term survival in patients with thyroid cancer. | Endocr Relat Cancer | 2016 Oct | Kim TH | doi: 10.1530/ERC-16-0219 |
28416747 | The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma. | Oncotarget | 2017 Apr 4 | Yuan X | doi: 10.18632/oncotarget.15498. |
27153563 | KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth. | Oncotarget | 2016 Aug 16 | Hu W | doi: 10.18632/oncotarget.9141. |
29066480 | Detection of the Single Nucleotide Polymorphism at Position rs2735940 in the Human Telomerase Reverse Transcriptase Gene by the Introduction of a New Restriction Enzyme Site for the PCR-RFLP Assay. | Ann Clin Lab Sci | 2017 Sep | Wang S | - |
28492540 | NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. | Cell Death Dis | 2017 May 11 | Feng X | doi: 10.1038/cddis.2017.200. |
27276713 | Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma. | Oncotarget | 2016 Aug 23 | Pezzuto F | doi: 10.18632/oncotarget.9801. |
27875244 | A six-genotype genetic prognostic model for papillary thyroid cancer. | Endocr Relat Cancer | 2017 Jan | Shen X | - |
26727717 | TERT Promoter Mutations and Tumor Persistence/Recurrence in Papillary Thyroid Cancer. | Cancer Res Treat | 2016 Jul | Myung JK | doi: 10.4143/crt.2015.362 |
28060765 | Genetic polymorphisms in TERT are associated with increased risk of esophageal cancer. | Oncotarget | 2017 Feb 7 | Wu Y | doi: 10.18632/oncotarget.14451. |
27437772 | A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study. | Oncotarget | 2016 Sep 6 | Castelo-Branco P | doi: 10.18632/oncotarget.10639. |
27852061 | Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT. | Oncotarget | 2016 Dec 27 | Bullock M | doi: 10.18632/oncotarget.13288. |
27825130 | Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population. | Oncotarget | 2016 Dec 13 | Duan X | doi: 10.18632/oncotarget.13102. |
29288666 | ZEB1 stimulates breast cancer growth by up-regulating hTERT expression. | Biochem Biophys Res Commun | 2018 Jan 22 | Yu P | doi: 10.1016/j.bbrc.2017.12.139 |
28616852 | Ultrasonographic prediction of highly aggressive telomerase reverse transcriptase (TERT) promoter-mutated papillary thyroid cancer. | Endocrine | 2017 Aug | Kim TH | doi: 10.1007/s12020-017-1340-3 |
29436188 | Peptide Nucleic Acid Clamping and Direct Sequencing in the Detection of Oncogenic Alterations in Lung Cancer: Systematic Review and Meta-Analysis. | Yonsei Med J | 2018 Mar | Song JU | doi: 10.3349/ymj.2018.59.2.211. |
27833153 | TERT promoter Mutation and Its Association with Clinicopathological Features and Prognosis of Papillary Thyroid Cancer: A Meta-analysis. | Sci Rep | 2016 Nov 11 | Liu C | doi: 10.1038/srep36990. |
28418878 | The TERT rs2736100 polymorphism increases cancer risk: A meta-analysis. | Oncotarget | 2017 Jun 13 | Li H | doi: 10.18632/oncotarget.16309. |
28296015 | Constitutional and functional genetics of human alcohol-related hepatocellular carcinoma. | Liver Int | 2017 Nov | Nahon P | doi: 10.1111/liv.13419 |
28754720 | TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker. | Oncologist | 2017 Oct | Liu L | doi: 10.1634/theoncologist.2017-0064 |
29534075 | Association between TERT rs2853669 polymorphism and cancer risk: A meta-analysis of 9,157 cases and 11,073 controls. | PLoS One | 2018 Mar 13 | Liu Z | doi: 10.1371/journal.pone.0191560 |
30024548 | The role of TERT promoter mutations in postoperative and preoperative diagnosis and prognosis in thyroid cancer. | Medicine (Baltimore) | 2018 Jul | Jin A | doi: 10.1097/MD.0000000000011548. |
29506639 | Genetic polymorphisms in human telomerase reverse transcriptase (hTERT) gene polymorphisms do not associated with breast cancer in patients in a turkish population: hospital-based case-control study. | Cell Mol Biol (Noisy-le-grand) | 2018 Feb 28 | Aydin M | doi: 10.14715/cmb/2018.64.1.3. |
29693804 | Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression | Asian Pac J Cancer Prev | 2018 Apr 25 | Rasouli S | - |
30088231 | hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression. | J Appl Genet | 2018 Nov | Sobecka A | doi: 10.1007/s13353-018-0458-1 |
29749533 | EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in nonsmall cell lung cancer cells. | Oncol Rep | 2018 Jul | Lin C | doi: 10.3892/or.2018.6417 |
30026550 | CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells. | Nat Commun | 2018 Jul 19 | Feng X | doi: 10.1038/s41467-018-05154-z. |
29603728 | Distinct profiles of TERT promoter mutations and telomerase expression in head and neck cancer and cervical carcinoma. | Int J Cancer | 2018 Sep 1 | Annunziata C | doi: 10.1002/ijc.31412 |
30082712 | NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer. | Nat Commun | 2018 Aug 6 | Ludlow AT | doi: 10.1038/s41467-018-05582-x. |
29939218 | rs401681 and rs402710 confer lung cancer susceptibility by regulating TERT expression instead of CLPTM1L in East Asian populations. | Carcinogenesis | 2018 Oct 8 | Yang YC | doi: 10.1093/carcin/bgy084. |