EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000164609 (Gene tree)
Gene ID: 10569
Gene Symbol: SLU7
Alias: 9G8
Full Name: SLU7 homolog, splicing factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 20,071 bases
Position: chr5:160,401,641-160,421,711
Accession: 16939
RBP type: canonical RBP
Summary: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000297151	Slu7	PF11708.8	8.1e-108	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
1427075	An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.	Genes Dev	1992 Nov	Frank D	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000521826	SLU7-208	568	-	ENSP00000428943	143 (aa)	-	E5RK41
ENST00000523219	SLU7-209	600	-	-	- (aa)	-	-
ENST00000521190	SLU7-206	577	-	-	- (aa)	-	-
ENST00000520841	SLU7-205	680	-	-	- (aa)	-	-
ENST00000518268	SLU7-202	691	-	-	- (aa)	-	-
ENST00000521320	SLU7-207	492	-	-	- (aa)	-	-
ENST00000297151	SLU7-201	3793	XM_005265793	ENSP00000297151	586 (aa)	XP_011532720	O95391
ENST00000519349	SLU7-203	577	-	ENSP00000429990	124 (aa)	-	E5RGM7
ENST00000520664	SLU7-204	807	-	ENSP00000428362	101 (aa)	-	A0A0C4DGD2

Gene Model

Click here to download ENSG00000164609's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000164609	rs2910195	5	160417268	C	Common carotid intima-media thickness	29206233	[NR] unit increase	0.02179	EFO_0004860

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000164609's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000164609	SLU7	97	77.408	ENSAPOG00000011660	slu7	100	75.939	Acanthochromis_polyacanthus
ENSG00000164609	SLU7	100	97.611	ENSAMEG00000006613	SLU7	100	97.611	Ailuropoda_melanoleuca
ENSG00000164609	SLU7	97	79.433	ENSACIG00000005652	slu7	99	74.055	Amphilophus_citrinellus
ENSG00000164609	SLU7	98	76.379	ENSAPEG00000018095	slu7	98	77.583	Amphiprion_percula
ENSG00000164609	SLU7	98	76.736	ENSATEG00000006357	slu7	99	76.736	Anabas_testudineus
ENSG00000164609	SLU7	99	85.495	ENSAPLG00000008133	SLU7	99	85.495	Anas_platyrhynchos
ENSG00000164609	SLU7	100	85.374	ENSACAG00000003144	SLU7	100	85.204	Anolis_carolinensis
ENSG00000164609	SLU7	100	100.000	ENSANAG00000028320	SLU7	100	99.147	Aotus_nancymaae
ENSG00000164609	SLU7	97	76.592	ENSACLG00000007273	slu7	98	76.936	Astatotilapia_calliptera
ENSG00000164609	SLU7	97	78.131	ENSAMXG00000002404	slu7	97	77.544	Astyanax_mexicanus
ENSG00000164609	SLU7	100	97.440	ENSBTAG00000008457	SLU7	100	97.440	Bos_taurus
ENSG00000164609	SLU7	82	55.085	WBGene00010629	K07C5.6	65	49.324	Caenorhabditis_elegans
ENSG00000164609	SLU7	100	99.194	ENSCJAG00000019132	SLU7	100	98.294	Callithrix_jacchus
ENSG00000164609	SLU7	100	98.294	ENSCAFG00000017268	SLU7	93	98.294	Canis_familiaris
ENSG00000164609	SLU7	100	98.294	ENSCAFG00020001456	SLU7	93	98.294	Canis_lupus_dingo
ENSG00000164609	SLU7	100	97.440	ENSCHIG00000013793	SLU7	100	97.440	Capra_hircus
ENSG00000164609	SLU7	100	97.440	ENSTSYG00000000157	SLU7	100	97.440	Carlito_syrichta
ENSG00000164609	SLU7	100	95.804	ENSCAPG00000015711	SLU7	100	89.761	Cavia_aperea
ENSG00000164609	SLU7	100	95.804	ENSCPOG00000004484	SLU7	100	94.881	Cavia_porcellus
ENSG00000164609	SLU7	100	98.976	ENSCCAG00000035808	SLU7	99	98.976	Cebus_capucinus
ENSG00000164609	SLU7	100	100.000	ENSCATG00000026140	SLU7	100	99.147	Cercocebus_atys
ENSG00000164609	SLU7	100	95.563	ENSCLAG00000011915	SLU7	100	95.563	Chinchilla_lanigera
ENSG00000164609	SLU7	100	100.000	ENSCSAG00000010383	SLU7	99	99.182	Chlorocebus_sabaeus
ENSG00000164609	SLU7	100	85.495	ENSCHOG00000005055	SLU7	100	85.495	Choloepus_hoffmanni
ENSG00000164609	SLU7	100	85.520	ENSCPBG00000008047	SLU7	100	86.371	Chrysemys_picta_bellii
ENSG00000164609	SLU7	80	77.391	ENSCING00000008595	zf(cchc)-12	76	67.770	Ciona_intestinalis
ENSG00000164609	SLU7	70	53.052	ENSCSAVG00000004927	-	100	54.567	Ciona_savignyi
ENSG00000164609	SLU7	100	100.000	ENSCANG00000003257	SLU7	100	99.317	Colobus_angolensis_palliatus
ENSG00000164609	SLU7	100	78.226	ENSCGRG00001022223	-	99	68.376	Cricetulus_griseus_chok1gshd
ENSG00000164609	SLU7	100	96.587	ENSCGRG00001016416	Slu7	100	96.587	Cricetulus_griseus_chok1gshd
ENSG00000164609	SLU7	100	96.246	ENSCGRG00000005164	Slu7	100	96.246	Cricetulus_griseus_crigri
ENSG00000164609	SLU7	100	79.839	ENSCGRG00000008655	-	99	68.718	Cricetulus_griseus_crigri
ENSG00000164609	SLU7	87	85.484	ENSCSEG00000015522	slu7	98	75.263	Cynoglossus_semilaevis
ENSG00000164609	SLU7	95	85.294	ENSCVAG00000019302	slu7	99	76.460	Cyprinodon_variegatus
ENSG00000164609	SLU7	97	78.947	ENSDARG00000038870	slu7	90	78.947	Danio_rerio
ENSG00000164609	SLU7	100	95.105	ENSDNOG00000048745	SLU7	100	94.369	Dasypus_novemcinctus
ENSG00000164609	SLU7	93	78.938	ENSDORG00000025365	-	99	78.388	Dipodomys_ordii
ENSG00000164609	SLU7	100	94.406	ENSDORG00000006239	-	99	82.594	Dipodomys_ordii
ENSG00000164609	SLU7	100	76.238	ENSDORG00000024886	-	100	73.529	Dipodomys_ordii
ENSG00000164609	SLU7	94	62.319	FBgn0039626	Slu7	73	58.186	Drosophila_melanogaster
ENSG00000164609	SLU7	90	93.951	ENSETEG00000014798	-	100	93.195	Echinops_telfairi
ENSG00000164609	SLU7	83	85.714	ENSETEG00000002993	-	100	73.051	Echinops_telfairi
ENSG00000164609	SLU7	100	71.774	ENSEBUG00000003656	slu7	90	64.164	Eptatretus_burgeri
ENSG00000164609	SLU7	100	97.445	ENSEASG00005000613	SLU7	100	97.445	Equus_asinus_asinus
ENSG00000164609	SLU7	100	97.270	ENSECAG00000013696	SLU7	100	97.270	Equus_caballus
ENSG00000164609	SLU7	100	94.059	ENSEEUG00000006300	-	61	96.414	Erinaceus_europaeus
ENSG00000164609	SLU7	92	84.043	ENSELUG00000022607	slu7	97	74.431	Esox_lucius
ENSG00000164609	SLU7	100	98.123	ENSFCAG00000011152	SLU7	100	98.123	Felis_catus
ENSG00000164609	SLU7	99	86.231	ENSFALG00000013473	-	100	86.078	Ficedula_albicollis
ENSG00000164609	SLU7	100	79.208	ENSFALG00000014860	-	99	84.080	Ficedula_albicollis
ENSG00000164609	SLU7	100	95.804	ENSFDAG00000003906	SLU7	100	94.881	Fukomys_damarensis
ENSG00000164609	SLU7	87	91.129	ENSFHEG00000012789	slu7	98	77.719	Fundulus_heteroclitus
ENSG00000164609	SLU7	87	83.065	ENSGMOG00000016207	slu7	98	68.607	Gadus_morhua
ENSG00000164609	SLU7	99	87.780	ENSGALG00000034414	SLU7	86	88.316	Gallus_gallus
ENSG00000164609	SLU7	96	83.453	ENSGAFG00000007953	slu7	97	77.153	Gambusia_affinis
ENSG00000164609	SLU7	92	81.061	ENSGACG00000018144	slu7	99	69.573	Gasterosteus_aculeatus
ENSG00000164609	SLU7	100	85.690	ENSGAGG00000008256	SLU7	100	86.542	Gopherus_agassizii
ENSG00000164609	SLU7	100	100.000	ENSGGOG00000005591	SLU7	100	99.829	Gorilla_gorilla
ENSG00000164609	SLU7	87	86.290	ENSHBUG00000002296	slu7	92	83.105	Haplochromis_burtoni
ENSG00000164609	SLU7	100	95.804	ENSHGLG00000009442	-	100	95.222	Heterocephalus_glaber_female
ENSG00000164609	SLU7	97	88.776	ENSHGLG00000008195	-	92	82.158	Heterocephalus_glaber_female
ENSG00000164609	SLU7	97	88.776	ENSHGLG00100011540	-	99	71.616	Heterocephalus_glaber_male
ENSG00000164609	SLU7	100	95.804	ENSHGLG00100008080	-	100	95.222	Heterocephalus_glaber_male
ENSG00000164609	SLU7	97	76.829	ENSHCOG00000003110	slu7	98	77.178	Hippocampus_comes
ENSG00000164609	SLU7	87	87.903	ENSIPUG00000017949	slu7	98	77.058	Ictalurus_punctatus
ENSG00000164609	SLU7	81	93.671	ENSSTOG00000015057	SLU7	98	93.671	Ictidomys_tridecemlineatus
ENSG00000164609	SLU7	100	96.503	ENSJJAG00000011452	Slu7	100	94.710	Jaculus_jaculus
ENSG00000164609	SLU7	97	82.270	ENSKMAG00000005625	slu7	100	76.271	Kryptolebias_marmoratus
ENSG00000164609	SLU7	87	87.903	ENSLBEG00000004903	slu7	98	76.140	Labrus_bergylta
ENSG00000164609	SLU7	100	81.122	ENSLACG00000010170	SLU7	100	81.803	Latimeria_chalumnae
ENSG00000164609	SLU7	97	80.776	ENSLOCG00000009410	slu7	98	80.702	Lepisosteus_oculatus
ENSG00000164609	SLU7	100	94.406	ENSLAFG00000003725	SLU7	100	93.345	Loxodonta_africana
ENSG00000164609	SLU7	100	100.000	ENSMFAG00000002001	SLU7	100	99.317	Macaca_fascicularis
ENSG00000164609	SLU7	100	100.000	ENSMMUG00000023075	SLU7	100	97.099	Macaca_mulatta
ENSG00000164609	SLU7	100	100.000	ENSMNEG00000029132	SLU7	100	99.488	Macaca_nemestrina
ENSG00000164609	SLU7	100	100.000	ENSMLEG00000037647	SLU7	100	99.147	Mandrillus_leucophaeus
ENSG00000164609	SLU7	90	84.733	ENSMAMG00000008387	slu7	99	75.171	Mastacembelus_armatus
ENSG00000164609	SLU7	97	78.383	ENSMZEG00005012180	slu7	98	77.641	Maylandia_zebra
ENSG00000164609	SLU7	99	87.435	ENSMGAG00000002882	SLU7	99	87.973	Meleagris_gallopavo
ENSG00000164609	SLU7	100	97.203	ENSMAUG00000016739	Slu7	100	97.104	Mesocricetus_auratus
ENSG00000164609	SLU7	100	97.440	ENSMICG00000031781	SLU7	100	97.440	Microcebus_murinus
ENSG00000164609	SLU7	100	96.503	ENSMOCG00000012963	Slu7	100	96.416	Microtus_ochrogaster
ENSG00000164609	SLU7	100	79.720	ENSMMOG00000004203	slu7	100	75.597	Mola_mola
ENSG00000164609	SLU7	70	81.690	ENSMMOG00000005988	-	75	81.690	Mola_mola
ENSG00000164609	SLU7	100	90.630	ENSMODG00000007968	SLU7	95	90.460	Monodelphis_domestica
ENSG00000164609	SLU7	97	75.176	ENSMALG00000004247	slu7	98	75.176	Monopterus_albus
ENSG00000164609	SLU7	100	97.099	MGP_CAROLIEiJ_G0016222	Slu7	100	97.586	Mus_caroli
ENSG00000164609	SLU7	100	95.734	ENSMUSG00000020409	Slu7	99	96.538	Mus_musculus
ENSG00000164609	SLU7	100	96.587	MGP_PahariEiJ_G0017358	Slu7	100	96.982	Mus_pahari
ENSG00000164609	SLU7	100	96.928	MGP_SPRETEiJ_G0017063	Slu7	100	97.384	Mus_spretus
ENSG00000164609	SLU7	100	97.952	ENSMPUG00000013264	SLU7	93	97.952	Mustela_putorius_furo
ENSG00000164609	SLU7	100	96.587	ENSMLUG00000003091	SLU7	100	96.587	Myotis_lucifugus
ENSG00000164609	SLU7	100	97.270	ENSNGAG00000015167	Slu7	100	97.270	Nannospalax_galili
ENSG00000164609	SLU7	100	100.000	ENSNLEG00000004355	SLU7	100	99.488	Nomascus_leucogenys
ENSG00000164609	SLU7	100	88.811	ENSMEUG00000010577	SLU7	99	83.959	Notamacropus_eugenii
ENSG00000164609	SLU7	100	95.105	ENSOPRG00000004538	SLU7	99	88.245	Ochotona_princeps
ENSG00000164609	SLU7	100	95.904	ENSODEG00000010998	-	100	95.904	Octodon_degus
ENSG00000164609	SLU7	100	93.069	ENSODEG00000005892	-	97	94.064	Octodon_degus
ENSG00000164609	SLU7	95	82.353	ENSONIG00000012957	slu7	99	78.141	Oreochromis_niloticus
ENSG00000164609	SLU7	100	86.713	ENSOANG00000008090	-	99	92.097	Ornithorhynchus_anatinus
ENSG00000164609	SLU7	65	85.938	ENSOANG00000012329	-	99	85.938	Ornithorhynchus_anatinus
ENSG00000164609	SLU7	100	98.020	ENSOCUG00000011743	SLU7	99	94.710	Oryctolagus_cuniculus
ENSG00000164609	SLU7	99	80.142	ENSORLG00000005505	slu7	97	76.280	Oryzias_latipes
ENSG00000164609	SLU7	97	80.576	ENSORLG00020011665	slu7	99	76.158	Oryzias_latipes_hni
ENSG00000164609	SLU7	99	79.433	ENSORLG00015002040	slu7	99	76.370	Oryzias_latipes_hsok
ENSG00000164609	SLU7	97	77.368	ENSOMEG00000006235	slu7	97	77.544	Oryzias_melastigma
ENSG00000164609	SLU7	100	97.902	ENSOGAG00000012301	SLU7	100	97.782	Otolemur_garnettii
ENSG00000164609	SLU7	100	96.928	ENSOARG00000013468	SLU7	100	96.928	Ovis_aries
ENSG00000164609	SLU7	100	100.000	ENSPPAG00000032717	SLU7	100	99.829	Pan_paniscus
ENSG00000164609	SLU7	100	97.782	ENSPPRG00000013856	SLU7	100	97.782	Panthera_pardus
ENSG00000164609	SLU7	100	97.782	ENSPTIG00000005434	SLU7	100	97.782	Panthera_tigris_altaica
ENSG00000164609	SLU7	100	100.000	ENSPTRG00000017491	SLU7	100	99.659	Pan_troglodytes
ENSG00000164609	SLU7	100	100.000	ENSPANG00000006850	SLU7	100	98.976	Papio_anubis
ENSG00000164609	SLU7	97	76.801	ENSPKIG00000009367	slu7	98	77.329	Paramormyrops_kingsleyae
ENSG00000164609	SLU7	100	85.149	ENSPSIG00000011216	SLU7	100	84.459	Pelodiscus_sinensis
ENSG00000164609	SLU7	87	88.710	ENSPMGG00000015695	slu7	96	73.545	Periophthalmus_magnuspinnatus
ENSG00000164609	SLU7	97	82.014	ENSPEMG00000000564	-	99	78.007	Peromyscus_maniculatus_bairdii
ENSG00000164609	SLU7	100	96.928	ENSPEMG00000016646	-	100	96.928	Peromyscus_maniculatus_bairdii
ENSG00000164609	SLU7	100	89.510	ENSPCIG00000018111	SLU7	99	89.483	Phascolarctos_cinereus
ENSG00000164609	SLU7	87	89.516	ENSPFOG00000009050	slu7	98	77.018	Poecilia_formosa
ENSG00000164609	SLU7	87	89.516	ENSPLAG00000005330	slu7	98	77.058	Poecilia_latipinna
ENSG00000164609	SLU7	87	89.516	ENSPMEG00000024369	slu7	98	77.465	Poecilia_mexicana
ENSG00000164609	SLU7	87	89.516	ENSPREG00000004355	slu7	98	76.585	Poecilia_reticulata
ENSG00000164609	SLU7	100	100.000	ENSPPYG00000016008	SLU7	100	99.488	Pongo_abelii
ENSG00000164609	SLU7	77	97.436	ENSPCAG00000003323	SLU7	85	97.436	Procavia_capensis
ENSG00000164609	SLU7	100	97.902	ENSPCOG00000016138	SLU7	100	94.027	Propithecus_coquereli
ENSG00000164609	SLU7	100	96.040	ENSPVAG00000015935	SLU7	82	96.296	Pteropus_vampyrus
ENSG00000164609	SLU7	85	84.426	ENSPNYG00000004141	-	88	79.602	Pundamilia_nyererei
ENSG00000164609	SLU7	94	63.339	ENSPNYG00000024087	-	97	63.573	Pundamilia_nyererei
ENSG00000164609	SLU7	87	86.290	ENSPNYG00000000289	slu7	98	77.641	Pundamilia_nyererei
ENSG00000164609	SLU7	97	78.131	ENSPNAG00000006885	slu7	98	78.070	Pygocentrus_nattereri
ENSG00000164609	SLU7	100	95.222	ENSRNOG00000003822	Slu7	100	94.378	Rattus_norvegicus
ENSG00000164609	SLU7	100	100.000	ENSRBIG00000021391	SLU7	100	95.918	Rhinopithecus_bieti
ENSG00000164609	SLU7	100	100.000	ENSRROG00000008930	SLU7	100	99.317	Rhinopithecus_roxellana
ENSG00000164609	SLU7	100	98.805	ENSSBOG00000003225	SLU7	100	98.805	Saimiri_boliviensis_boliviensis
ENSG00000164609	SLU7	100	90.630	ENSSHAG00000009841	-	100	90.460	Sarcophilus_harrisii
ENSG00000164609	SLU7	99	82.253	ENSSHAG00000007807	-	100	81.538	Sarcophilus_harrisii
ENSG00000164609	SLU7	97	80.141	ENSSFOG00015015923	slu7	97	80.316	Scleropages_formosus
ENSG00000164609	SLU7	95	80.435	ENSSMAG00000004281	slu7	99	73.935	Scophthalmus_maximus
ENSG00000164609	SLU7	97	76.708	ENSSDUG00000005127	slu7	98	76.708	Seriola_dumerili
ENSG00000164609	SLU7	87	87.097	ENSSLDG00000014353	slu7	98	77.058	Seriola_lalandi_dorsalis
ENSG00000164609	SLU7	93	91.729	ENSSARG00000014137	-	100	86.111	Sorex_araneus
ENSG00000164609	SLU7	93	90.977	ENSSARG00000014139	-	100	85.243	Sorex_araneus
ENSG00000164609	SLU7	93	90.977	ENSSARG00000006390	-	100	87.770	Sorex_araneus
ENSG00000164609	SLU7	93	91.729	ENSSARG00000001869	-	100	84.028	Sorex_araneus
ENSG00000164609	SLU7	100	80.375	ENSSARG00000012209	-	100	80.375	Sorex_araneus
ENSG00000164609	SLU7	93	89.474	ENSSARG00000014506	-	100	84.916	Sorex_araneus
ENSG00000164609	SLU7	93	91.729	ENSSARG00000006902	-	100	84.896	Sorex_araneus
ENSG00000164609	SLU7	89	90.551	ENSSARG00000014128	-	100	87.288	Sorex_araneus
ENSG00000164609	SLU7	61	81.461	ENSSARG00000006540	-	100	80.672	Sorex_araneus
ENSG00000164609	SLU7	100	84.915	ENSSPUG00000000666	SLU7	100	85.932	Sphenodon_punctatus
ENSG00000164609	SLU7	97	76.842	ENSSPAG00000014100	slu7	99	75.510	Stegastes_partitus
ENSG00000164609	SLU7	100	96.758	ENSSSCG00000017033	SLU7	100	96.758	Sus_scrofa
ENSG00000164609	SLU7	99	86.403	ENSTGUG00000001410	SLU7	99	86.248	Taeniopygia_guttata
ENSG00000164609	SLU7	87	87.097	ENSTRUG00000001335	slu7	98	73.739	Takifugu_rubripes
ENSG00000164609	SLU7	87	88.710	ENSTNIG00000009677	slu7	100	76.049	Tetraodon_nigroviridis
ENSG00000164609	SLU7	100	82.082	ENSTBEG00000015604	SLU7	99	81.741	Tupaia_belangeri
ENSG00000164609	SLU7	90	95.652	ENSTTRG00000011575	SLU7	100	94.896	Tursiops_truncatus
ENSG00000164609	SLU7	100	97.782	ENSUMAG00000000110	SLU7	92	97.782	Ursus_maritimus
ENSG00000164609	SLU7	100	95.050	ENSVPAG00000009595	SLU7	100	94.198	Vicugna_pacos
ENSG00000164609	SLU7	100	98.464	ENSVVUG00000003989	SLU7	93	98.464	Vulpes_vulpes
ENSG00000164609	SLU7	98	79.376	ENSXETG00000016536	slu7	100	81.781	Xenopus_tropicalis
ENSG00000164609	SLU7	87	90.323	ENSXCOG00000004207	slu7	98	76.720	Xiphophorus_couchianus
ENSG00000164609	SLU7	87	90.323	ENSXMAG00000009007	slu7	98	77.193	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000375	RNA splicing, via transesterification reactions	10197984.	IDA	Process
GO:0000380	alternative mRNA splicing, via spliceosome	15728250.	IDA	Process
GO:0000386	second spliceosomal transesterification activity	21873635.	IBA	Function
GO:0000386	second spliceosomal transesterification activity	10197984.	IDA	Function
GO:0000389	mRNA 3'-splice site recognition	15728250.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0005515	protein binding	16189514.22365833.23455924.25416956.	IPI	Function
GO:0005634	nucleus	21122810.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005681	spliceosomal complex	21873635.	IBA	Component
GO:0005681	spliceosomal complex	10197984.	IDA	Component
GO:0005737	cytoplasm	21122810.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006405	RNA export from nucleus	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006886	intracellular protein transport	21122810.	IDA	Process
GO:0008270	zinc ion binding	15181151.	IDA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0016607	nuclear speck	15728250.	IDA	Component
GO:0030532	small nuclear ribonucleoprotein complex	15181151.	IDA	Component
GO:0030628	pre-mRNA 3'-splice site binding	15728250.	IDA	Function
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0034605	cellular response to heat	21122810.	IDA	Process
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component