EuRBPDB

Description

Ensembl ID: ENSG00000164880 (Gene tree)
Gene ID: 26173
Gene Symbol: INTS1
Alias: DKFZp586J0619|KIAA1440|INT1|NET28
Full Name: integrator complex subunit 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 34,106 bases
Position: chr7:1,470,277-1,504,382
Accession: 24555
RBP type: non-canonical RBP
Summary: INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000496988	INTS1-208	421	-	-	- (aa)	-	-
ENST00000479671	INTS1-203	245	-	-	- (aa)	-	-
ENST00000493531	INTS1-207	828	-	-	- (aa)	-	-
ENST00000404767	INTS1-201	6959	XM_011515260	ENSP00000385722	2190 (aa)	XP_011513562	Q8N201
ENST00000482994	INTS1-204	498	-	-	- (aa)	-	-
ENST00000483196	INTS1-205	386	-	ENSP00000419206	128 (aa)	-	H7C582
ENST00000493446	INTS1-206	675	-	-	- (aa)	-	-
ENST00000468115	INTS1-202	3051	-	-	- (aa)	-	-

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005654	nucleoplasm	-	TAS	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016180	snRNA processing	16239144.	IDA	Process
GO:0031965	nuclear membrane	-	IEA	Component
GO:0032039	integrator complex	21873635.	IBA	Component
GO:0032039	integrator complex	16239144.	IDA	Component
GO:0034474	U2 snRNA 3'-end processing	21873635.	IBA	Process
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process