EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000165061 (Gene tree)
Gene ID: 79698
Gene Symbol: ZMAT4
Alias: FLJ13842
Full Name: zinc finger matrin-type 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 367,244 bases
Position: chr8:40,530,590-40,897,833
Accession: 25844
RBP type: canonical RBP
Summary: ZMAT4 (Zinc Finger Matrin-Type 4) is a Protein Coding gene. Diseases associated with ZMAT4 include Refractive Error. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF346.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000297737	zf-met	PF12874.7	3.3e-27	1	4
ENSP00000297737	zf-met	PF12874.7	3.3e-27	2	4
ENSP00000297737	zf-met	PF12874.7	3.3e-27	3	4
ENSP00000297737	zf-met	PF12874.7	3.3e-27	4	4
ENSP00000428423	zf-met	PF12874.7	2.6e-22	1	3
ENSP00000428423	zf-met	PF12874.7	2.6e-22	2	3
ENSP00000428423	zf-met	PF12874.7	2.6e-22	3	3
ENSP00000319785	zf-met	PF12874.7	3.3e-20	1	3
ENSP00000319785	zf-met	PF12874.7	3.3e-20	2	3
ENSP00000319785	zf-met	PF12874.7	3.3e-20	3	3
ENSP00000297737	zf-C2H2_jaz	PF12171.8	2.3e-23	1	2
ENSP00000297737	zf-C2H2_jaz	PF12171.8	2.3e-23	2	2
ENSP00000428423	zf-C2H2_jaz	PF12171.8	2e-18	1	2
ENSP00000428423	zf-C2H2_jaz	PF12171.8	2e-18	2	2
ENSP00000319785	zf-C2H2_jaz	PF12171.8	1.2e-15	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000523542	ZMAT4-208	515	-	ENSP00000427918	46 (aa)	-	E5RFW2
ENST00000519406	ZMAT4-204	690	XM_017013836	ENSP00000428423	211 (aa)	XP_016869325	E5RIF5
ENST00000518242	ZMAT4-203	590	-	-	- (aa)	-	-
ENST00000315769	ZMAT4-202	2250	-	ENSP00000319785	153 (aa)	-	Q9H898
ENST00000523823	ZMAT4-209	571	-	-	- (aa)	-	-
ENST00000519806	ZMAT4-205	661	-	-	- (aa)	-	-
ENST00000523188	ZMAT4-207	564	-	ENSP00000430050	61 (aa)	-	E5RGZ7
ENST00000522623	ZMAT4-206	473	-	ENSP00000429068	46 (aa)	-	E5RFW2
ENST00000297737	ZMAT4-201	2466	XM_024447276	ENSP00000297737	229 (aa)	XP_024303044	Q9H898

Gene Model

Click here to download ENSG00000165061's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000165061	Bipolar Disorder	2.02E-5	19488044
ENSG00000165061	Parkinson Disease	4.88E-5	21829596
ENSG00000165061	Parkinson Disease	4.82E-5	21829596
ENSG00000165061	Alcoholism	1.17271e-005	22978509
ENSG00000165061	Alcoholism	1.35334e-005	22978509
ENSG00000165061	Alcoholism	1.93804e-005	22978509
ENSG00000165061	Alcoholism	2.11665e-005	22978509
ENSG00000165061	Erythrocyte Indices	5.882e-005	-
ENSG00000165061	Erythrocyte Count	5.243e-005	-
ENSG00000165061	Personality	5.647e-005	-
ENSG00000165061	Personality	7.956e-005	-
ENSG00000165061	Waist-Hip Ratio	9.5270000E-005	-
ENSG00000165061	Coronary Artery Disease	2.5670000E-005	-
ENSG00000165061	Coronary Artery Disease	4.1200000E-005	-
ENSG00000165061	Platelet Function Tests	1.9518700E-005	-
ENSG00000165061	Platelet Function Tests	1.3500000E-006	-
ENSG00000165061	Platelet Function Tests	8.1000000E-007	-
ENSG00000165061	Child Development Disorders, Pervasive	4.0413000E-005	-
ENSG00000165061	Cryptoxanthins	1.5120000E-005	-
ENSG00000165061	Lung Neoplasms	2.2150000E-005	-
ENSG00000165061	Glucose	2E-8	17903298
ENSG00000165061	Education	1E-7	27020472
ENSG00000165061	Refractive Errors	1E-7	27020472
ENSG00000165061	Education	4E-9	27020472
ENSG00000165061	Refractive Errors	4E-9	27020472
ENSG00000165061	Myopia	4E-31	27182965
ENSG00000165061	S-(3-hydroxypropyl)cysteine N-acetate	3E-7	26053186
ENSG00000165061	Smoking	3E-7	26053186
ENSG00000165061	Glucose	9E-6	17903298
ENSG00000165061	Refraction, Ocular	4E-10	23396134

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000165061	rs2137277	8	40877143	A	Spherical equivalent (joint analysis main effects and education interaction)	27020472			EFO_0004784\|EFO_0007814
ENSG00000165061	rs2137277	8	40877143	A	Spherical equivalent (joint analysis main effects and education interaction)	27020472			EFO_0004784\|EFO_0007814
ENSG00000165061	rs7829127	8	40868875	G	Refractive error	23396134	[0.081-0.151] unit increase	0.116	HP_0000539
ENSG00000165061	rs7829127	8	40868875	A	Myopia (age of diagnosis)	29808027	[0.074-0.109] unit decrease	0.0915	EFO_0004847\|HP_0000545
ENSG00000165061	rs7829127	8	40868875	A	Spherical equivalent or myopia (age of diagnosis)	29808027	[NR] z score decrease	10.911	EFO_0004847\|HP_0000545\|EFO_0007814
ENSG00000165061	rs75321045	8	40625519	G	Pediatric areal bone mineral density (concordant skeletal phenotype)	29240982	[0.39-0.83] unit increase	0.61	EFO_0003923
ENSG00000165061	rs75321045	8	40625519	G	Pediatric areal bone mineral density (concordant skeletal phenotype)	29240982	[0.39-0.83] unit increase	0.61	EFO_0003923
ENSG00000165061	rs2722425	8	40626720	?	Fasting plasma glucose	17903298			EFO_0004465
ENSG00000165061	rs2722425	8	40626720	?	Fasting plasma glucose	17903298			EFO_0004465
ENSG00000165061	rs869422	8	40866451	?	Myopia	27182965	[1.09-1.13]	1.1074197	HP_0000545
ENSG00000165061	rs4472504	8	40689598	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000165061's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000165061	ZMAT4	87	63.317	ENSAPOG00000007448	zmat4a	97	63.317	Acanthochromis_polyacanthus
ENSG00000165061	ZMAT4	100	97.630	ENSAMEG00000002758	ZMAT4	100	97.768	Ailuropoda_melanoleuca
ENSG00000165061	ZMAT4	99	75.714	ENSACIG00000009080	zmat4a	99	76.233	Amphilophus_citrinellus
ENSG00000165061	ZMAT4	100	76.856	ENSAOCG00000004416	zmat4a	87	76.856	Amphiprion_ocellaris
ENSG00000165061	ZMAT4	100	76.419	ENSAPEG00000018565	zmat4a	87	76.419	Amphiprion_percula
ENSG00000165061	ZMAT4	99	76.190	ENSATEG00000012630	zmat4a	85	81.818	Anabas_testudineus
ENSG00000165061	ZMAT4	100	83.886	ENSAPLG00000006106	ZMAT4	100	83.843	Anas_platyrhynchos
ENSG00000165061	ZMAT4	92	84.615	ENSACAG00000005388	ZMAT4	93	84.615	Anolis_carolinensis
ENSG00000165061	ZMAT4	100	100.000	ENSANAG00000027926	ZMAT4	100	100.000	Aotus_nancymaae
ENSG00000165061	ZMAT4	100	76.419	ENSACLG00000005038	zmat4a	87	76.419	Astatotilapia_calliptera
ENSG00000165061	ZMAT4	99	71.362	ENSAMXG00000035337	zmat4a	99	74.439	Astyanax_mexicanus
ENSG00000165061	ZMAT4	100	97.817	ENSBTAG00000017420	ZMAT4	100	97.817	Bos_taurus
ENSG00000165061	ZMAT4	100	98.104	ENSCAFG00000005744	ZMAT4	100	97.817	Canis_familiaris
ENSG00000165061	ZMAT4	72	95.395	ENSCAFG00020002716	ZMAT4	96	95.152	Canis_lupus_dingo
ENSG00000165061	ZMAT4	100	96.943	ENSCHIG00000022017	ZMAT4	100	96.943	Capra_hircus
ENSG00000165061	ZMAT4	72	98.788	ENSTSYG00000031413	ZMAT4	100	100.000	Carlito_syrichta
ENSG00000165061	ZMAT4	100	96.070	ENSCAPG00000014401	ZMAT4	100	96.070	Cavia_aperea
ENSG00000165061	ZMAT4	100	96.070	ENSCPOG00000015224	ZMAT4	100	96.070	Cavia_porcellus
ENSG00000165061	ZMAT4	100	100.000	ENSCCAG00000027437	ZMAT4	100	100.000	Cebus_capucinus
ENSG00000165061	ZMAT4	100	100.000	ENSCATG00000044978	ZMAT4	100	100.000	Cercocebus_atys
ENSG00000165061	ZMAT4	100	97.380	ENSCLAG00000000923	ZMAT4	100	97.380	Chinchilla_lanigera
ENSG00000165061	ZMAT4	100	100.000	ENSCSAG00000015108	ZMAT4	100	100.000	Chlorocebus_sabaeus
ENSG00000165061	ZMAT4	100	98.291	ENSCHOG00000003755	ZMAT4	100	98.291	Choloepus_hoffmanni
ENSG00000165061	ZMAT4	86	84.848	ENSCPBG00000002781	ZMAT4	82	84.848	Chrysemys_picta_bellii
ENSG00000165061	ZMAT4	85	100.000	ENSCANG00000032136	ZMAT4	100	100.000	Colobus_angolensis_palliatus
ENSG00000165061	ZMAT4	100	94.787	ENSCGRG00001016583	Zmat4	100	94.760	Cricetulus_griseus_chok1gshd
ENSG00000165061	ZMAT4	100	94.787	ENSCGRG00000002696	Zmat4	100	94.760	Cricetulus_griseus_crigri
ENSG00000165061	ZMAT4	100	75.983	ENSCSEG00000013707	zmat4a	97	75.983	Cynoglossus_semilaevis
ENSG00000165061	ZMAT4	100	75.652	ENSCVAG00000000113	zmat4a	87	75.652	Cyprinodon_variegatus
ENSG00000165061	ZMAT4	99	66.981	ENSDARG00000061419	zmat4b	99	67.699	Danio_rerio
ENSG00000165061	ZMAT4	96	78.912	ENSDARG00000092987	zmat4a	99	78.912	Danio_rerio
ENSG00000165061	ZMAT4	100	96.682	ENSDNOG00000001045	ZMAT4	100	96.875	Dasypus_novemcinctus
ENSG00000165061	ZMAT4	100	98.690	ENSDORG00000009300	Zmat4	100	98.690	Dipodomys_ordii
ENSG00000165061	ZMAT4	75	98.101	ENSETEG00000010474	ZMAT4	81	98.101	Echinops_telfairi
ENSG00000165061	ZMAT4	100	97.380	ENSEASG00005010447	ZMAT4	100	97.380	Equus_asinus_asinus
ENSG00000165061	ZMAT4	100	98.253	ENSECAG00000021550	ZMAT4	100	98.253	Equus_caballus
ENSG00000165061	ZMAT4	100	82.938	ENSEEUG00000002565	ZMAT4	100	83.929	Erinaceus_europaeus
ENSG00000165061	ZMAT4	99	77.619	ENSELUG00000005097	zmat4a	99	78.027	Esox_lucius
ENSG00000165061	ZMAT4	100	100.000	ENSFCAG00000012775	ZMAT4	100	100.000	Felis_catus
ENSG00000165061	ZMAT4	100	80.786	ENSFALG00000006455	ZMAT4	100	80.786	Ficedula_albicollis
ENSG00000165061	ZMAT4	100	95.197	ENSFDAG00000015258	ZMAT4	97	95.197	Fukomys_damarensis
ENSG00000165061	ZMAT4	99	74.762	ENSFHEG00000022872	zmat4b	99	75.000	Fundulus_heteroclitus
ENSG00000165061	ZMAT4	99	75.238	ENSGMOG00000007950	zmat4a	99	75.785	Gadus_morhua
ENSG00000165061	ZMAT4	100	82.969	ENSGALG00000003470	ZMAT4	100	82.969	Gallus_gallus
ENSG00000165061	ZMAT4	100	74.672	ENSGAFG00000013149	zmat4a	100	74.672	Gambusia_affinis
ENSG00000165061	ZMAT4	100	79.085	ENSGACG00000005515	zmat4a	100	79.085	Gasterosteus_aculeatus
ENSG00000165061	ZMAT4	100	85.590	ENSGAGG00000004799	ZMAT4	100	85.590	Gopherus_agassizii
ENSG00000165061	ZMAT4	100	100.000	ENSGGOG00000006633	ZMAT4	100	100.000	Gorilla_gorilla
ENSG00000165061	ZMAT4	100	76.419	ENSHBUG00000012634	zmat4a	87	76.419	Haplochromis_burtoni
ENSG00000165061	ZMAT4	100	93.886	ENSHGLG00000003246	ZMAT4	100	93.886	Heterocephalus_glaber_female
ENSG00000165061	ZMAT4	75	91.772	ENSHGLG00100000081	ZMAT4	100	91.772	Heterocephalus_glaber_male
ENSG00000165061	ZMAT4	74	88.235	ENSHCOG00000006516	zmat4b	94	83.051	Hippocampus_comes
ENSG00000165061	ZMAT4	99	73.333	ENSIPUG00000022248	zmat4	99	73.991	Ictalurus_punctatus
ENSG00000165061	ZMAT4	54	61.364	ENSSTOG00000026946	-	100	96.429	Ictidomys_tridecemlineatus
ENSG00000165061	ZMAT4	100	94.787	ENSJJAG00000013484	Zmat4	100	94.760	Jaculus_jaculus
ENSG00000165061	ZMAT4	99	78.509	ENSLACG00000006206	-	99	78.509	Latimeria_chalumnae
ENSG00000165061	ZMAT4	69	54.362	ENSLACG00000005109	-	96	54.362	Latimeria_chalumnae
ENSG00000165061	ZMAT4	99	75.943	ENSLOCG00000015435	zmat4b	99	75.877	Lepisosteus_oculatus
ENSG00000165061	ZMAT4	100	96.698	ENSLAFG00000014753	ZMAT4	100	96.889	Loxodonta_africana
ENSG00000165061	ZMAT4	100	100.000	ENSMFAG00000043475	ZMAT4	100	100.000	Macaca_fascicularis
ENSG00000165061	ZMAT4	85	100.000	ENSMMUG00000000776	ZMAT4	100	100.000	Macaca_mulatta
ENSG00000165061	ZMAT4	100	100.000	ENSMNEG00000042102	ZMAT4	100	100.000	Macaca_nemestrina
ENSG00000165061	ZMAT4	100	100.000	ENSMLEG00000034448	ZMAT4	100	100.000	Mandrillus_leucophaeus
ENSG00000165061	ZMAT4	100	75.546	ENSMAMG00000019914	zmat4a	78	81.356	Mastacembelus_armatus
ENSG00000165061	ZMAT4	100	76.419	ENSMZEG00005004946	zmat4a	87	76.419	Maylandia_zebra
ENSG00000165061	ZMAT4	99	88.889	ENSMGAG00000002288	ZMAT4	99	88.889	Meleagris_gallopavo
ENSG00000165061	ZMAT4	54	60.227	ENSMAUG00000017272	-	100	91.964	Mesocricetus_auratus
ENSG00000165061	ZMAT4	74	100.000	ENSMAUG00000004169	-	79	100.000	Mesocricetus_auratus
ENSG00000165061	ZMAT4	85	97.949	ENSMICG00000047837	ZMAT4	100	97.949	Microcebus_murinus
ENSG00000165061	ZMAT4	100	94.323	ENSMOCG00000015996	Zmat4	100	94.323	Microtus_ochrogaster
ENSG00000165061	ZMAT4	100	77.293	ENSMMOG00000012619	zmat4a	87	82.203	Mola_mola
ENSG00000165061	ZMAT4	84	84.021	ENSMODG00000010499	ZMAT4	97	84.021	Monodelphis_domestica
ENSG00000165061	ZMAT4	100	74.138	ENSMALG00000015056	zmat4a	87	74.138	Monopterus_albus
ENSG00000165061	ZMAT4	100	94.787	MGP_CAROLIEiJ_G0030909	Zmat4	100	98.958	Mus_caroli
ENSG00000165061	ZMAT4	100	94.787	ENSMUSG00000037492	Zmat4	100	98.958	Mus_musculus
ENSG00000165061	ZMAT4	100	94.787	MGP_PahariEiJ_G0021380	Zmat4	100	98.958	Mus_pahari
ENSG00000165061	ZMAT4	100	94.787	MGP_SPRETEiJ_G0032028	Zmat4	100	98.958	Mus_spretus
ENSG00000165061	ZMAT4	100	98.104	ENSMPUG00000005832	ZMAT4	80	96.916	Mustela_putorius_furo
ENSG00000165061	ZMAT4	62	95.420	ENSMLUG00000014209	ZMAT4	98	95.420	Myotis_lucifugus
ENSG00000165061	ZMAT4	100	96.070	ENSNGAG00000015545	Zmat4	100	96.070	Nannospalax_galili
ENSG00000165061	ZMAT4	99	76.303	ENSNBRG00000011844	zmat4a	99	76.786	Neolamprologus_brichardi
ENSG00000165061	ZMAT4	100	100.000	ENSNLEG00000012564	ZMAT4	100	100.000	Nomascus_leucogenys
ENSG00000165061	ZMAT4	100	85.915	ENSMEUG00000000558	ZMAT4	100	86.726	Notamacropus_eugenii
ENSG00000165061	ZMAT4	100	99.127	ENSOPRG00000009257	ZMAT4	100	99.127	Ochotona_princeps
ENSG00000165061	ZMAT4	100	96.943	ENSODEG00000006439	ZMAT4	100	96.943	Octodon_degus
ENSG00000165061	ZMAT4	80	71.892	ENSONIG00000016086	zmat4a	99	71.892	Oreochromis_niloticus
ENSG00000165061	ZMAT4	93	46.316	ENSONIG00000020374	-	51	37.600	Oreochromis_niloticus
ENSG00000165061	ZMAT4	96	91.453	ENSOANG00000022431	ZMAT4	100	91.453	Ornithorhynchus_anatinus
ENSG00000165061	ZMAT4	100	98.690	ENSOCUG00000000977	ZMAT4	100	98.690	Oryctolagus_cuniculus
ENSG00000165061	ZMAT4	85	77.444	ENSORLG00000016169	zmat4b	91	77.444	Oryzias_latipes
ENSG00000165061	ZMAT4	100	79.085	ENSORLG00020019602	zmat4a	98	75.431	Oryzias_latipes_hni
ENSG00000165061	ZMAT4	100	79.085	ENSORLG00015009006	zmat4a	98	75.431	Oryzias_latipes_hsok
ENSG00000165061	ZMAT4	100	75.325	ENSOMEG00000003441	zmat4a	76	75.556	Oryzias_melastigma
ENSG00000165061	ZMAT4	100	97.156	ENSOGAG00000012558	ZMAT4	100	97.321	Otolemur_garnettii
ENSG00000165061	ZMAT4	100	96.682	ENSOARG00000002354	ZMAT4	84	96.875	Ovis_aries
ENSG00000165061	ZMAT4	100	100.000	ENSPPAG00000042573	ZMAT4	100	100.000	Pan_paniscus
ENSG00000165061	ZMAT4	100	99.346	ENSPPRG00000007023	ZMAT4	100	99.346	Panthera_pardus
ENSG00000165061	ZMAT4	100	99.346	ENSPTIG00000019738	ZMAT4	100	99.346	Panthera_tigris_altaica
ENSG00000165061	ZMAT4	100	100.000	ENSPTRG00000020191	ZMAT4	100	100.000	Pan_troglodytes
ENSG00000165061	ZMAT4	100	100.000	ENSPANG00000014196	ZMAT4	100	100.000	Papio_anubis
ENSG00000165061	ZMAT4	96	73.154	ENSPKIG00000021792	zmat4b	99	73.154	Paramormyrops_kingsleyae
ENSG00000165061	ZMAT4	100	76.856	ENSPKIG00000000048	zmat4a	87	76.856	Paramormyrops_kingsleyae
ENSG00000165061	ZMAT4	100	84.716	ENSPSIG00000004847	ZMAT4	100	84.716	Pelodiscus_sinensis
ENSG00000165061	ZMAT4	99	68.396	ENSPMGG00000001436	zmat4b	99	69.027	Periophthalmus_magnuspinnatus
ENSG00000165061	ZMAT4	97	52.000	ENSPMAG00000004582	zmat4a	97	52.000	Petromyzon_marinus
ENSG00000165061	ZMAT4	100	91.453	ENSPCIG00000028706	ZMAT4	92	91.453	Phascolarctos_cinereus
ENSG00000165061	ZMAT4	100	75.546	ENSPFOG00000006742	zmat4a	87	75.546	Poecilia_formosa
ENSG00000165061	ZMAT4	99	75.714	ENSPLAG00000019268	zmat4a	99	66.376	Poecilia_latipinna
ENSG00000165061	ZMAT4	100	75.546	ENSPMEG00000007870	zmat4a	98	75.546	Poecilia_mexicana
ENSG00000165061	ZMAT4	100	75.546	ENSPREG00000014914	zmat4a	87	75.546	Poecilia_reticulata
ENSG00000165061	ZMAT4	100	99.563	ENSPPYG00000018540	ZMAT4	100	99.563	Pongo_abelii
ENSG00000165061	ZMAT4	100	96.070	ENSPCAG00000004820	ZMAT4	100	96.070	Procavia_capensis
ENSG00000165061	ZMAT4	100	100.000	ENSPCOG00000007717	ZMAT4	100	100.000	Propithecus_coquereli
ENSG00000165061	ZMAT4	91	97.917	ENSPVAG00000011393	ZMAT4	84	97.917	Pteropus_vampyrus
ENSG00000165061	ZMAT4	100	76.856	ENSPNYG00000006173	zmat4a	81	76.856	Pundamilia_nyererei
ENSG00000165061	ZMAT4	100	74.672	ENSPNAG00000009604	zmat4a	87	74.672	Pygocentrus_nattereri
ENSG00000165061	ZMAT4	100	67.391	ENSPNAG00000023764	zmat4b	100	67.391	Pygocentrus_nattereri
ENSG00000165061	ZMAT4	100	97.436	ENSRNOG00000042690	Zmat4	100	97.436	Rattus_norvegicus
ENSG00000165061	ZMAT4	100	100.000	ENSRBIG00000031887	ZMAT4	100	100.000	Rhinopithecus_bieti
ENSG00000165061	ZMAT4	100	100.000	ENSRROG00000040877	ZMAT4	100	100.000	Rhinopithecus_roxellana
ENSG00000165061	ZMAT4	100	100.000	ENSSBOG00000017391	ZMAT4	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000165061	ZMAT4	90	90.141	ENSSHAG00000011847	ZMAT4	100	90.141	Sarcophilus_harrisii
ENSG00000165061	ZMAT4	57	92.308	ENSSFOG00015015440	zmat4b	84	78.641	Scleropages_formosus
ENSG00000165061	ZMAT4	100	77.293	ENSSFOG00015013158	zmat4	99	76.957	Scleropages_formosus
ENSG00000165061	ZMAT4	100	80.392	ENSSMAG00000017693	zmat4a	99	76.549	Scophthalmus_maximus
ENSG00000165061	ZMAT4	97	80.537	ENSSDUG00000005878	zmat4a	87	76.856	Seriola_dumerili
ENSG00000165061	ZMAT4	100	76.856	ENSSLDG00000012934	zmat4a	87	76.856	Seriola_lalandi_dorsalis
ENSG00000165061	ZMAT4	100	90.995	ENSSARG00000003679	ZMAT4	100	87.773	Sorex_araneus
ENSG00000165061	ZMAT4	99	77.143	ENSSPAG00000021408	zmat4a	83	77.578	Stegastes_partitus
ENSG00000165061	ZMAT4	100	97.817	ENSSSCG00000007010	ZMAT4	100	97.817	Sus_scrofa
ENSG00000165061	ZMAT4	100	83.412	ENSTGUG00000005159	ZMAT4	100	84.375	Taeniopygia_guttata
ENSG00000165061	ZMAT4	100	77.293	ENSTRUG00000005170	zmat4a	76	77.293	Takifugu_rubripes
ENSG00000165061	ZMAT4	99	67.453	ENSTNIG00000018863	zmat4b	99	67.699	Tetraodon_nigroviridis
ENSG00000165061	ZMAT4	100	84.279	ENSTBEG00000016172	ZMAT4	100	84.279	Tupaia_belangeri
ENSG00000165061	ZMAT4	100	98.291	ENSTTRG00000009606	ZMAT4	100	98.291	Tursiops_truncatus
ENSG00000165061	ZMAT4	100	97.630	ENSUMAG00000025578	ZMAT4	99	97.768	Ursus_maritimus
ENSG00000165061	ZMAT4	100	86.463	ENSVPAG00000009783	ZMAT4	100	86.463	Vicugna_pacos
ENSG00000165061	ZMAT4	100	98.253	ENSVVUG00000020407	ZMAT4	100	98.253	Vulpes_vulpes
ENSG00000165061	ZMAT4	74	88.235	ENSXCOG00000015061	zmat4b	92	61.538	Xiphophorus_couchianus
ENSG00000165061	ZMAT4	100	40.741	ENSXCOG00000010189	-	99	42.358	Xiphophorus_couchianus
ENSG00000165061	ZMAT4	100	75.109	ENSXMAG00000010461	zmat4a	87	75.109	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0008270	zinc ion binding	-	IEA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr8	40697388	Missense_Mutation	novel	D69G	0.15
BLCA	chr8	40674886	Missense_Mutation	NA	P132L	0.3
BLCA	chr8	40674762	Silent	rs747874868	A173A	0.4
BLCA	chr8	40674722	Missense_Mutation	novel	D187H	0.14
BRCA	chr8	40532174	3'UTR	rs372127993		0.1
BRCA	chr8	40531987	3'UTR	novel		0.21
BRCA	chr8	40532213	3'UTR	novel		0.23
CESC	chr8	40530637	3'UTR	novel		0.07
CESC	chr8	40674708	Silent	rs753809814	L191L	0.19
CESC	chr8	40530604	3'UTR	novel		0.38
CESC	chr8	40530781	3'UTR	novel		0.42
CESC	chr8	40674901	Missense_Mutation	NA	R127Q	0.26
CESC	chr8	40531032	3'UTR	novel		0.83
CESC	chr8	40697311	Missense_Mutation	novel	Q95E	0.52
COAD	chr8	40697389	Missense_Mutation	rs776568390	D69N	0.35
COAD	chr8	40674901	Missense_Mutation	NA	R127Q	0.5
COAD	chr8	40674902	Missense_Mutation	NA	R127W	0.14
COAD	chr8	40825577	Missense_Mutation	NA	E34K	0.19	zf-met
COAD	chr8	40532174	3'UTR	rs372127993		0.36
COAD	chr8	40697337	Missense_Mutation	NA	S86L	0.27
COAD	chr8	40674838	Missense_Mutation	NA	G148E	0.37
COAD	chr8	40581263	Splice_Site	novel	X193_splice	0.12
COAD	chr8	40767705	Missense_Mutation	rs377050986	R43Q	0.04
ESCA	chr8	40531577	3'UTR	novel		0.11
ESCA	chr8	40531696	3'UTR	novel		0.15
ESCA	chr8	40697390	Silent	rs149820458	A68A	0.27
ESCA	chr8	40581215	Missense_Mutation	novel	N208K	0.8
GBM	chr8	40674811	Missense_Mutation	rs760109127	P157L	0.2
GBM	chr8	40697342	Missense_Mutation	NA	F84L	0.4
GBM	chr8	40674768	Missense_Mutation	novel	K171N	0.48
GBM	chr8	40697297	Silent	rs189553545	H99H	0.56
GBM	chr8	40825610	Silent	novel	L23L	0.46
HNSC	chr8	40697328	Missense_Mutation	novel	V89A	0.26
HNSC	chr8	40674825	Silent	novel	A152A	0.24
HNSC	chr8	40697244	Splice_Site	NA	X117_splice	0.08
HNSC	chr8	40674746	Silent	novel	L179L	0.06
HNSC	chr8	40674840	Silent	novel	C147C	0.16
HNSC	chr8	40697267	Silent	novel	E109E	0.08
LGG	chr8	40697250	Missense_Mutation	NA	T115I	0.35
LGG	chr8	40674901	Missense_Mutation	NA	R127Q	0.36
LIHC	chr8	40674822	Nonsense_Mutation	NA	W153*	0.22
LIHC	chr8	40825666	Missense_Mutation	NA	S4F	0.43
LIHC	chr8	40674734	Missense_Mutation	novel	G183W	0.41
LIHC	chr8	40532190	3'UTR	novel		0.07
LIHC	chr8	40825666	Missense_Mutation	NA	S4F	0.09
LIHC	chr8	40697325	Missense_Mutation	NA	A90V	0.29
LUAD	chr8	40532101	3'UTR	novel		0.2
LUAD	chr8	40674725	Missense_Mutation	novel	L186M	0.15
LUAD	chr8	40697383	Missense_Mutation	novel	V71L	0.26
LUAD	chr8	40767726	Missense_Mutation	novel	R36L	0.14	zf-met
LUAD	chr8	40674717	Missense_Mutation	NA	M188I	0.35
LUAD	chr8	40581190	Missense_Mutation	NA	L217M	0.53
LUAD	chr8	40674841	Missense_Mutation	NA	C147F	0.36
LUAD	chr8	40674732	Frame_Shift_Del	novel	*T184Qfs8**	0.11
LUAD	chr8	40674707	Nonsense_Mutation	NA	R192*	0.3
LUAD	chr8	40581175	Missense_Mutation	NA	H222N	0.41
LUAD	chr8	40697391	Missense_Mutation	NA	A68D	0.39
LUAD	chr8	40581229	Missense_Mutation	NA	S204C	0.34
LUSC	chr8	40674888	Silent	novel	A131A	0.12
LUSC	chr8	40532087	3'UTR	novel		0.08
LUSC	chr8	40697403	Splice_Site	NA	X65_splice	0.46
LUSC	chr8	40697390	Silent	novel	A68A	0.19
LUSC	chr8	40767675	In_Frame_Ins	novel	G53delinsER	0.07
LUSC	chr8	40532173	3'UTR	rs367883917		0.19
LUSC	chr8	40674857	Missense_Mutation	novel	D142H	0.1
LUSC	chr8	40697365	Missense_Mutation	NA	C77S	0.12
LUSC	chr8	40581253	Missense_Mutation	NA	R196S	0.21
LUSC	chr8	40697261	Silent	novel	T111T	0.2
OV	chr8	40674875	Frame_Shift_Ins	novel	*S136Tfs31**	0.22
PAAD	chr8	40674851	Missense_Mutation	novel	D144H	0.07
PAAD	chr8	40532176	3'UTR	novel		0.14
READ	chr8	40697325	Missense_Mutation	NA	A90V	0.08
READ	chr8	40825578	Silent	rs375382251	Y33Y	0.41
SARC	chr8	40674800	Missense_Mutation	novel	Q161K	0.18
SARC	chr8	40530716	3'UTR	novel		0.34
SKCM	chr8	40674763	Missense_Mutation	rs769291323	A173V	0.46
SKCM	chr8	40674713	Missense_Mutation	novel	E190K	0.28
SKCM	chr8	40697311	Nonsense_Mutation	NA	Q95*	0.35
SKCM	chr8	40532221	3'UTR	novel		0.23
SKCM	chr8	40581190	Silent	novel	L217L	0.29
SKCM	chr8	40674866	Nonsense_Mutation	NA	Q139*	0.76
SKCM	chr8	40674804	Missense_Mutation	NA	M159I	0.18
SKCM	chr8	40674761	Missense_Mutation	NA	A174T	0.48
SKCM	chr8	40674847	Missense_Mutation	novel	R145K	0.37
SKCM	chr8	40697250	Missense_Mutation	NA	T115I	0.23
SKCM	chr8	40697395	Missense_Mutation	novel	D67N	0.58
SKCM	chr8	40674874	Missense_Mutation	novel	S136F	0.42
SKCM	chr8	40767653	Silent	NA	L60L	0.18
SKCM	chr8	40674897	Missense_Mutation	NA	M128I	0.25
SKCM	chr8	40532138	3'UTR	novel		0.46
SKCM	chr8	40697299	Missense_Mutation	NA	H99Y	0.3
SKCM	chr8	40581236	Silent	novel	T201T	0.51
SKCM	chr8	40767646	Missense_Mutation	novel	E63K	0.54
SKCM	chr8	40674717	Missense_Mutation	NA	M188I	0.34
SKCM	chr8	40697319	Missense_Mutation	rs368933570	S92F	0.83
SKCM	chr8	40532209	3'UTR	novel		0.47
SKCM	chr8	40697380	Missense_Mutation	NA	D72N	0.12
SKCM	chr8	40697332	Missense_Mutation	novel	V88M	0.26
SKCM	chr8	40674768	Silent	NA	K171K	0.37
SKCM	chr8	40697311	Nonsense_Mutation	NA	Q95*	0.2
STAD	chr8	40767664	Missense_Mutation	NA	A57S	0.08
STAD	chr8	40674910	Missense_Mutation	NA	K124R	0.31
STAD	chr8	40674849	Silent	novel	D144D	0.33
STAD	chr8	40767651	Missense_Mutation	rs751036977	R61Q	0.74
STAD	chr8	40697402	Splice_Site	NA	X65_splice	0.29
STAD	chr8	40697323	Missense_Mutation	rs773491757	D91N	0.06
THYM	chr8	40532033	3'UTR	novel		0.48
UCEC	chr8	40532116	3'UTR	novel		0.36
UCEC	chr8	40532033	3'UTR	novel		0.39
UCEC	chr8	40530878	3'UTR	novel		0.28
UCEC	chr8	40674763	Missense_Mutation	rs769291323	A173V	0.44
UCEC	chr8	40674762	Silent	rs747874868	A173A	0.39
UCEC	chr8	40531430	3'UTR	novel		0.44
UCEC	chr8	40531590	3'UTR	novel		0.26
UCEC	chr8	40825601	Missense_Mutation	NA	E26K	0.23	zf-met
UCEC	chr8	40697358	Missense_Mutation	NA	L79H	0.11
UCEC	chr8	40825581	Silent	novel	H32H	0.37
UCEC	chr8	40531620	3'UTR	novel		0.2
UCEC	chr8	40532083	3'UTR	novel		0.3
UCEC	chr8	40532174	3'UTR	rs372127993		0.16
UCEC	chr8	40531694	3'UTR	novel		0.39
UCEC	chr8	40532213	3'UTR	novel		0.48
UCEC	chr8	40767655	Missense_Mutation	novel	L60F	0.22
UCEC	chr8	40531804	3'UTR	novel		0.62
UCEC	chr8	40532180	3'UTR	novel		0.53
UCEC	chr8	40531590	3'UTR	novel		0.23
UCEC	chr8	40530635	3'UTR	novel		0.48
UCEC	chr8	40532072	3'UTR	novel		0.5
UCEC	chr8	40674901	Missense_Mutation	NA	R127Q	0.32
UCEC	chr8	40532087	3'UTR	novel		0.28
UCEC	chr8	40532138	3'UTR	novel		0.45
UCEC	chr8	40825633	Missense_Mutation	NA	Y15C	0.32	zf-met
UCEC	chr8	40532055	3'UTR	novel		0.47
UCEC	chr8	40674845	Missense_Mutation	novel	Y146N	0.42
UCEC	chr8	40532180	3'UTR	novel		0.28
UCEC	chr8	40532138	3'UTR	novel		0.1
UCEC	chr8	40530808	3'UTR	novel		0.37
UCEC	chr8	40530983	3'UTR	novel		0.32
UCEC	chr8	40531625	3'UTR	novel		0.37
UCEC	chr8	40531073	3'UTR	novel		0.44
UCEC	chr8	40532138	3'UTR	novel		0.5
UCEC	chr8	40530685	3'UTR	novel		0.3
UCEC	chr8	40697389	Missense_Mutation	rs776568390	D69N	0.44
UCS	chr8	40581183	Missense_Mutation	novel	G219A	0.88

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ESCA	DEL	0.2283	0.060925
PAAD	AMP	0.0924	0.06475
READ	DEL	0.2121	0.20625

Survival Analysis

Cancer	P-value	Q-value
STAD	0.036	Kaplan-Meier Survival Analysis
ACC	0.042	Kaplan-Meier Survival Analysis
HNSC	0.031	Kaplan-Meier Survival Analysis
KIRP	0.042	Kaplan-Meier Survival Analysis
BLCA	0.011	Kaplan-Meier Survival Analysis
LAML	0.027	Kaplan-Meier Survival Analysis
UCEC	0.046	Kaplan-Meier Survival Analysis
LGG	0.042	Kaplan-Meier Survival Analysis
THCA	0.021	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742