EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000165526 (Gene tree)
Gene ID: 84881
Gene Symbol: RPUSD4
Alias: FLJ14494
Full Name: RNA pseudouridine synthase D4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 9,599 bases
Position: chr11:126,202,094-126,211,692
Accession: 25898
RBP type: canonical RBP
Summary: (RNA Pseudouridine Synthase D4) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include pseudouridine synthase activity. An important paralog of this gene is RPUSD3.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000298317	PseudoU_synth_2	PF00849.22	2.6e-34	1	1
ENSP00000433065	PseudoU_synth_2	PF00849.22	1.5e-33	1	1
ENSP00000433709	PseudoU_synth_2	PF00849.22	5.3e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000530036	RPUSD4-204	566	-	-	- (aa)	-	-
ENST00000532800	RPUSD4-207	1030	-	-	- (aa)	-	-
ENST00000530903	RPUSD4-205	1404	-	-	- (aa)	-	-
ENST00000532674	RPUSD4-206	582	-	ENSP00000433709	176 (aa)	-	E9PJV3
ENST00000534393	RPUSD4-209	579	-	-	- (aa)	-	-
ENST00000298317	RPUSD4-201	2512	XM_011543039	ENSP00000298317	377 (aa)	XP_011541341	Q96CM3
ENST00000525812	RPUSD4-202	580	-	-	- (aa)	-	-
ENST00000533628	RPUSD4-208	2053	-	ENSP00000433065	346 (aa)	-	Q96CM3
ENST00000526942	RPUSD4-203	1791	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000165526's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000165526's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000165526	RPUSD4	89	50.292	ENSAPOG00000011024	rpusd4	81	51.682	Acanthochromis_polyacanthus
ENSG00000165526	RPUSD4	83	74.483	ENSAMEG00000005953	-	100	74.483	Ailuropoda_melanoleuca
ENSG00000165526	RPUSD4	100	81.963	ENSAMEG00000000127	-	100	81.963	Ailuropoda_melanoleuca
ENSG00000165526	RPUSD4	86	50.301	ENSACIG00000003533	rpusd4	94	50.617	Amphilophus_citrinellus
ENSG00000165526	RPUSD4	86	51.662	ENSAOCG00000015409	rpusd4	80	52.147	Amphiprion_ocellaris
ENSG00000165526	RPUSD4	86	51.662	ENSAPEG00000018935	rpusd4	80	52.147	Amphiprion_percula
ENSG00000165526	RPUSD4	87	50.301	ENSATEG00000008059	rpusd4	80	50.765	Anabas_testudineus
ENSG00000165526	RPUSD4	73	61.290	ENSAPLG00000013250	RPUSD4	99	59.727	Anas_platyrhynchos
ENSG00000165526	RPUSD4	88	64.865	ENSACAG00000000189	RPUSD4	89	65.846	Anolis_carolinensis
ENSG00000165526	RPUSD4	99	89.247	ENSANAG00000024050	RPUSD4	100	89.247	Aotus_nancymaae
ENSG00000165526	RPUSD4	86	51.057	ENSACLG00000020996	rpusd4	83	51.534	Astatotilapia_calliptera
ENSG00000165526	RPUSD4	83	51.104	ENSAMXG00000031479	rpusd4	89	51.104	Astyanax_mexicanus
ENSG00000165526	RPUSD4	100	78.307	ENSBTAG00000020900	RPUSD4	100	77.778	Bos_taurus
ENSG00000165526	RPUSD4	98	89.730	ENSCJAG00000042850	RPUSD4	93	89.730	Callithrix_jacchus
ENSG00000165526	RPUSD4	100	80.159	ENSCAFG00000010488	RPUSD4	100	80.159	Canis_familiaris
ENSG00000165526	RPUSD4	100	80.159	ENSCAFG00020010621	RPUSD4	100	80.159	Canis_lupus_dingo
ENSG00000165526	RPUSD4	100	77.836	ENSCHIG00000009975	RPUSD4	100	77.573	Capra_hircus
ENSG00000165526	RPUSD4	100	85.411	ENSTSYG00000008456	RPUSD4	100	85.411	Carlito_syrichta
ENSG00000165526	RPUSD4	68	79.457	ENSCAPG00000006040	RPUSD4	100	79.457	Cavia_aperea
ENSG00000165526	RPUSD4	100	79.310	ENSCPOG00000014971	RPUSD4	100	79.310	Cavia_porcellus
ENSG00000165526	RPUSD4	99	89.785	ENSCCAG00000027838	RPUSD4	100	89.785	Cebus_capucinus
ENSG00000165526	RPUSD4	100	92.308	ENSCATG00000041570	RPUSD4	100	92.308	Cercocebus_atys
ENSG00000165526	RPUSD4	100	83.820	ENSCLAG00000016553	RPUSD4	100	83.820	Chinchilla_lanigera
ENSG00000165526	RPUSD4	100	92.042	ENSCSAG00000002274	RPUSD4	100	92.042	Chlorocebus_sabaeus
ENSG00000165526	RPUSD4	75	82.332	ENSCHOG00000010249	RPUSD4	100	82.332	Choloepus_hoffmanni
ENSG00000165526	RPUSD4	75	68.881	ENSCPBG00000011175	RPUSD4	98	69.123	Chrysemys_picta_bellii
ENSG00000165526	RPUSD4	71	42.806	ENSCSAVG00000000872	-	54	42.806	Ciona_savignyi
ENSG00000165526	RPUSD4	100	90.451	ENSCANG00000039684	RPUSD4	100	90.451	Colobus_angolensis_palliatus
ENSG00000165526	RPUSD4	100	82.493	ENSCGRG00001024141	Rpusd4	100	82.493	Cricetulus_griseus_chok1gshd
ENSG00000165526	RPUSD4	100	82.493	ENSCGRG00000014415	Rpusd4	100	82.493	Cricetulus_griseus_crigri
ENSG00000165526	RPUSD4	67	47.934	ENSCSEG00000006462	-	76	46.591	Cynoglossus_semilaevis
ENSG00000165526	RPUSD4	87	50.904	ENSCVAG00000000392	rpusd4	92	51.376	Cyprinodon_variegatus
ENSG00000165526	RPUSD4	87	50.602	ENSCVAG00000008761	rpusd4	83	51.070	Cyprinodon_variegatus
ENSG00000165526	RPUSD4	90	47.965	ENSDARG00000012674	rpusd4	90	49.068	Danio_rerio
ENSG00000165526	RPUSD4	100	76.127	ENSDNOG00000020026	RPUSD4	100	76.127	Dasypus_novemcinctus
ENSG00000165526	RPUSD4	100	80.371	ENSDORG00000016717	Rpusd4	100	80.371	Dipodomys_ordii
ENSG00000165526	RPUSD4	98	77.778	ENSETEG00000013953	RPUSD4	98	77.778	Echinops_telfairi
ENSG00000165526	RPUSD4	100	82.228	ENSEASG00005022982	RPUSD4	100	82.228	Equus_asinus_asinus
ENSG00000165526	RPUSD4	100	81.963	ENSECAG00000000557	RPUSD4	100	81.963	Equus_caballus
ENSG00000165526	RPUSD4	80	80.978	ENSEEUG00000014036	RPUSD4	80	80.978	Erinaceus_europaeus
ENSG00000165526	RPUSD4	93	50.820	ENSELUG00000008075	rpusd4	87	53.293	Esox_lucius
ENSG00000165526	RPUSD4	100	81.167	ENSFCAG00000029789	RPUSD4	100	81.167	Felis_catus
ENSG00000165526	RPUSD4	88	57.186	ENSFALG00000005171	RPUSD4	95	58.075	Ficedula_albicollis
ENSG00000165526	RPUSD4	100	81.842	ENSFDAG00000014307	RPUSD4	100	81.842	Fukomys_damarensis
ENSG00000165526	RPUSD4	88	50.888	ENSFHEG00000004329	rpusd4	84	51.682	Fundulus_heteroclitus
ENSG00000165526	RPUSD4	85	50.462	ENSGMOG00000017726	rpusd4	95	50.938	Gadus_morhua
ENSG00000165526	RPUSD4	87	57.313	ENSGALG00000024326	RPUSD4	93	58.133	Gallus_gallus
ENSG00000165526	RPUSD4	90	47.578	ENSGAFG00000021559	rpusd4	84	48.193	Gambusia_affinis
ENSG00000165526	RPUSD4	89	47.353	ENSGACG00000001657	rpusd4	97	49.286	Gasterosteus_aculeatus
ENSG00000165526	RPUSD4	89	64.583	ENSGAGG00000000132	RPUSD4	89	66.355	Gopherus_agassizii
ENSG00000165526	RPUSD4	100	98.408	ENSGGOG00000016494	RPUSD4	100	98.408	Gorilla_gorilla
ENSG00000165526	RPUSD4	86	51.057	ENSHBUG00000022838	rpusd4	83	51.534	Haplochromis_burtoni
ENSG00000165526	RPUSD4	100	83.024	ENSHGLG00000002285	RPUSD4	100	83.024	Heterocephalus_glaber_female
ENSG00000165526	RPUSD4	100	83.024	ENSHGLG00100006385	RPUSD4	100	83.024	Heterocephalus_glaber_male
ENSG00000165526	RPUSD4	86	51.672	ENSHCOG00000006612	rpusd4	82	52.322	Hippocampus_comes
ENSG00000165526	RPUSD4	90	50.292	ENSIPUG00000023879	rusd4	83	52.648	Ictalurus_punctatus
ENSG00000165526	RPUSD4	97	83.516	ENSSTOG00000025280	RPUSD4	100	83.516	Ictidomys_tridecemlineatus
ENSG00000165526	RPUSD4	99	82.258	ENSJJAG00000018673	Rpusd4	100	82.258	Jaculus_jaculus
ENSG00000165526	RPUSD4	89	50.737	ENSKMAG00000021805	rpusd4	84	51.840	Kryptolebias_marmoratus
ENSG00000165526	RPUSD4	92	47.765	ENSLBEG00000020394	rpusd4	90	50.621	Labrus_bergylta
ENSG00000165526	RPUSD4	85	61.963	ENSLACG00000011028	RPUSD4	80	62.617	Latimeria_chalumnae
ENSG00000165526	RPUSD4	86	46.341	ENSLOCG00000003124	rpusd4	85	47.213	Lepisosteus_oculatus
ENSG00000165526	RPUSD4	100	81.481	ENSLAFG00000005211	RPUSD4	100	81.481	Loxodonta_africana
ENSG00000165526	RPUSD4	100	92.573	ENSMFAG00000039513	RPUSD4	100	92.573	Macaca_fascicularis
ENSG00000165526	RPUSD4	100	92.573	ENSMMUG00000007933	RPUSD4	100	92.573	Macaca_mulatta
ENSG00000165526	RPUSD4	100	92.573	ENSMNEG00000027414	RPUSD4	100	92.573	Macaca_nemestrina
ENSG00000165526	RPUSD4	100	91.777	ENSMLEG00000042461	RPUSD4	100	91.777	Mandrillus_leucophaeus
ENSG00000165526	RPUSD4	85	50.769	ENSMAMG00000023839	rpusd4	83	50.769	Mastacembelus_armatus
ENSG00000165526	RPUSD4	86	51.057	ENSMZEG00005011999	rpusd4	83	51.534	Maylandia_zebra
ENSG00000165526	RPUSD4	84	58.125	ENSMGAG00000000840	RPUSD4	99	58.025	Meleagris_gallopavo
ENSG00000165526	RPUSD4	100	80.371	ENSMAUG00000010280	Rpusd4	100	80.371	Mesocricetus_auratus
ENSG00000165526	RPUSD4	100	82.759	ENSMICG00000015979	RPUSD4	100	82.759	Microcebus_murinus
ENSG00000165526	RPUSD4	100	77.719	ENSMOCG00000000661	Rpusd4	100	77.719	Microtus_ochrogaster
ENSG00000165526	RPUSD4	82	51.429	ENSMMOG00000021731	rpusd4	93	51.429	Mola_mola
ENSG00000165526	RPUSD4	87	75.229	ENSMODG00000004521	RPUSD4	84	75.229	Monodelphis_domestica
ENSG00000165526	RPUSD4	80	52.614	ENSMALG00000005839	rpusd4	98	50.926	Monopterus_albus
ENSG00000165526	RPUSD4	100	79.310	MGP_CAROLIEiJ_G0031954	Rpusd4	100	79.310	Mus_caroli
ENSG00000165526	RPUSD4	100	78.515	ENSMUSG00000032044	Rpusd4	100	78.515	Mus_musculus
ENSG00000165526	RPUSD4	100	78.780	MGP_PahariEiJ_G0014819	Rpusd4	100	78.780	Mus_pahari
ENSG00000165526	RPUSD4	100	78.780	MGP_SPRETEiJ_G0033078	Rpusd4	100	78.780	Mus_spretus
ENSG00000165526	RPUSD4	98	79.515	ENSMPUG00000006608	RPUSD4	99	79.515	Mustela_putorius_furo
ENSG00000165526	RPUSD4	99	78.989	ENSMLUG00000017328	-	99	77.867	Myotis_lucifugus
ENSG00000165526	RPUSD4	67	83.465	ENSMLUG00000029348	-	100	83.465	Myotis_lucifugus
ENSG00000165526	RPUSD4	98	78.437	ENSNGAG00000020847	Rpusd4	98	78.437	Nannospalax_galili
ENSG00000165526	RPUSD4	87	51.506	ENSNBRG00000005207	rpusd4	94	51.840	Neolamprologus_brichardi
ENSG00000165526	RPUSD4	100	95.491	ENSNLEG00000007465	RPUSD4	100	95.491	Nomascus_leucogenys
ENSG00000165526	RPUSD4	98	69.189	ENSMEUG00000004370	RPUSD4	98	69.189	Notamacropus_eugenii
ENSG00000165526	RPUSD4	99	41.398	ENSOPRG00000013141	-	100	61.887	Ochotona_princeps
ENSG00000165526	RPUSD4	100	80.902	ENSODEG00000004577	RPUSD4	100	80.902	Octodon_degus
ENSG00000165526	RPUSD4	89	50.581	ENSONIG00000018879	rpusd4	87	52.294	Oreochromis_niloticus
ENSG00000165526	RPUSD4	77	69.492	ENSOANG00000007247	RPUSD4	95	69.360	Ornithorhynchus_anatinus
ENSG00000165526	RPUSD4	98	82.210	ENSOCUG00000017039	RPUSD4	98	82.210	Oryctolagus_cuniculus
ENSG00000165526	RPUSD4	91	48.138	ENSORLG00000002750	rpusd4	91	49.699	Oryzias_latipes
ENSG00000165526	RPUSD4	88	48.961	ENSORLG00020002044	rpusd4	82	49.398	Oryzias_latipes_hni
ENSG00000165526	RPUSD4	88	49.258	ENSORLG00015020034	rpusd4	82	49.699	Oryzias_latipes_hsok
ENSG00000165526	RPUSD4	89	50.292	ENSOMEG00000004861	rpusd4	82	50.742	Oryzias_melastigma
ENSG00000165526	RPUSD4	100	81.217	ENSOGAG00000008922	RPUSD4	100	81.217	Otolemur_garnettii
ENSG00000165526	RPUSD4	98	78.378	ENSOARG00000012238	RPUSD4	99	77.249	Ovis_aries
ENSG00000165526	RPUSD4	100	99.735	ENSPPAG00000042883	RPUSD4	93	99.735	Pan_paniscus
ENSG00000165526	RPUSD4	100	81.167	ENSPPRG00000003081	RPUSD4	100	81.167	Panthera_pardus
ENSG00000165526	RPUSD4	100	81.167	ENSPTIG00000012059	RPUSD4	100	81.167	Panthera_tigris_altaica
ENSG00000165526	RPUSD4	100	99.469	ENSPTRG00000004454	RPUSD4	100	99.469	Pan_troglodytes
ENSG00000165526	RPUSD4	100	92.308	ENSPANG00000015040	RPUSD4	100	92.308	Papio_anubis
ENSG00000165526	RPUSD4	89	56.213	ENSPKIG00000023986	rpusd4	81	57.862	Paramormyrops_kingsleyae
ENSG00000165526	RPUSD4	79	67.114	ENSPSIG00000014268	RPUSD4	95	67.114	Pelodiscus_sinensis
ENSG00000165526	RPUSD4	86	49.695	ENSPMGG00000002806	rpusd4	89	50.155	Periophthalmus_magnuspinnatus
ENSG00000165526	RPUSD4	100	73.740	ENSPEMG00000000278	Rpusd4	100	73.740	Peromyscus_maniculatus_bairdii
ENSG00000165526	RPUSD4	81	44.868	ENSPMAG00000008183	rpusd4	98	44.543	Petromyzon_marinus
ENSG00000165526	RPUSD4	93	74.212	ENSPCIG00000010212	RPUSD4	100	72.253	Phascolarctos_cinereus
ENSG00000165526	RPUSD4	85	51.376	ENSPFOG00000019030	rpusd4	84	51.376	Poecilia_formosa
ENSG00000165526	RPUSD4	85	52.000	ENSPLAG00000016848	rpusd4	81	52.000	Poecilia_latipinna
ENSG00000165526	RPUSD4	90	48.718	ENSPMEG00000017534	rpusd4	84	50.149	Poecilia_mexicana
ENSG00000165526	RPUSD4	84	50.303	ENSPREG00000005689	rpusd4	80	51.911	Poecilia_reticulata
ENSG00000165526	RPUSD4	100	97.878	ENSPPYG00000004043	RPUSD4	100	97.878	Pongo_abelii
ENSG00000165526	RPUSD4	80	80.978	ENSPCAG00000000753	RPUSD4	81	80.978	Procavia_capensis
ENSG00000165526	RPUSD4	98	75.741	ENSPCOG00000020694	RPUSD4	100	75.741	Propithecus_coquereli
ENSG00000165526	RPUSD4	97	82.561	ENSPVAG00000000988	RPUSD4	98	82.561	Pteropus_vampyrus
ENSG00000165526	RPUSD4	86	50.904	ENSPNYG00000009652	rpusd4	83	51.376	Pundamilia_nyererei
ENSG00000165526	RPUSD4	85	52.000	ENSPNAG00000012264	rpusd4	84	52.174	Pygocentrus_nattereri
ENSG00000165526	RPUSD4	100	79.576	ENSRNOG00000011567	Rpusd4	100	79.576	Rattus_norvegicus
ENSG00000165526	RPUSD4	100	91.512	ENSRBIG00000034842	RPUSD4	100	91.512	Rhinopithecus_bieti
ENSG00000165526	RPUSD4	100	91.512	ENSRROG00000039753	RPUSD4	100	91.512	Rhinopithecus_roxellana
ENSG00000165526	RPUSD4	99	88.441	ENSSBOG00000030413	RPUSD4	100	88.441	Saimiri_boliviensis_boliviensis
ENSG00000165526	RPUSD4	80	76.412	ENSSHAG00000008304	RPUSD4	99	76.412	Sarcophilus_harrisii
ENSG00000165526	RPUSD4	78	60.403	ENSSFOG00015006203	rpusd4	85	58.255	Scleropages_formosus
ENSG00000165526	RPUSD4	89	49.267	ENSSMAG00000020978	rpusd4	85	50.459	Scophthalmus_maximus
ENSG00000165526	RPUSD4	86	50.303	ENSSDUG00000013399	rpusd4	84	50.464	Seriola_dumerili
ENSG00000165526	RPUSD4	86	49.697	ENSSLDG00000023507	rpusd4	84	49.845	Seriola_lalandi_dorsalis
ENSG00000165526	RPUSD4	88	62.275	ENSSPUG00000001401	RPUSD4	90	63.692	Sphenodon_punctatus
ENSG00000165526	RPUSD4	94	47.135	ENSSPAG00000012163	rpusd4	84	51.829	Stegastes_partitus
ENSG00000165526	RPUSD4	100	80.371	ENSSSCG00000015233	RPUSD4	100	80.371	Sus_scrofa
ENSG00000165526	RPUSD4	78	60.269	ENSTGUG00000000773	RPUSD4	99	60.269	Taeniopygia_guttata
ENSG00000165526	RPUSD4	86	49.697	ENSTRUG00000012283	rpusd4	83	50.154	Takifugu_rubripes
ENSG00000165526	RPUSD4	87	49.096	ENSTNIG00000014676	rpusd4	83	49.541	Tetraodon_nigroviridis
ENSG00000165526	RPUSD4	100	80.106	ENSTTRG00000001555	RPUSD4	100	80.106	Tursiops_truncatus
ENSG00000165526	RPUSD4	99	71.505	ENSUAMG00000005503	-	97	81.720	Ursus_americanus
ENSG00000165526	RPUSD4	100	81.698	ENSUMAG00000002219	RPUSD4	100	81.698	Ursus_maritimus
ENSG00000165526	RPUSD4	99	69.355	ENSVPAG00000001066	RPUSD4	100	80.377	Vicugna_pacos
ENSG00000165526	RPUSD4	100	80.159	ENSVVUG00000020101	RPUSD4	100	80.159	Vulpes_vulpes
ENSG00000165526	RPUSD4	90	48.276	ENSXCOG00000004676	rpusd4	86	49.699	Xiphophorus_couchianus
ENSG00000165526	RPUSD4	90	48.563	ENSXMAG00000023351	rpusd4	84	50.000	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001522	pseudouridine synthesis	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	17577209.	IPI	Function
GO:0005759	mitochondrial matrix	-	IEA	Component
GO:0008033	tRNA processing	-	IEA	Process
GO:0009982	pseudouridine synthase activity	-	IEA	Function
GO:0070131	positive regulation of mitochondrial translation	27667664.	IMP	Process