EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000165733 (Gene tree)
Gene ID: 9790
Gene Symbol: BMS1
Alias: KIAA0187|BMS1L
Full Name: BMS1 ribosome biogenesis factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 52,432 bases
Position: chr10:42,782,506-42,834,937
Accession: 23505
RBP type: canonical RBP
Summary: This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.[provided by RefSeq, Mar 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000363642	AARP2CN	PF08142.12	5.8e-31	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19332556	A novel small-subunit processome assembly intermediate that contains the U3 snoRNP, nucleolin, RRP5, and DBP4.	Mol Cell Biol	2009 Jun	Turner AJ	doi: 10.1128/MCB.00029-09
16376378	GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis.	J Mol Biol	2006 Feb 17	Karbstein K	-
16307926	An essential GTPase promotes assembly of preribosomal RNA processing complexes.	Mol Cell	2005 Nov 23	Karbstein K	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374518	BMS1-201	7753	XM_005271846	ENSP00000363642	1282 (aa)	XP_005271903	Q14692

Gene Model

Click here to download ENSG00000165733's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000165733	Vitamin D	8.18219302516803E-5	17903293
ENSG00000165733	Diabetic Nephropathies	9.49E-5	19252134
ENSG00000165733	Neuroblastoma	8.11e-006	23222812
ENSG00000165733	Child Development Disorders, Pervasive	3.1400500E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	4.7000000E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	6.7000000E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	2.4000000E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	1.2000000E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	7.4200000E-006	-
ENSG00000165733	Child Development Disorders, Pervasive	5.6000000E-005	-
ENSG00000165733	Child Development Disorders, Pervasive	8.8600000E-006	-
ENSG00000165733	Bone Density	5E-6	28181694
ENSG00000165733	Supranuclear Palsy, Progressive	3E-7	21685912

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000165733's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000165733	BMS1	71	71.972	ENSAPOG00000002296	bms1	97	66.009	Acanthochromis_polyacanthus
ENSG00000165733	BMS1	99	89.588	ENSAMEG00000016834	BMS1	99	89.899	Ailuropoda_melanoleuca
ENSG00000165733	BMS1	86	69.044	ENSACIG00000002588	bms1	85	77.500	Amphilophus_citrinellus
ENSG00000165733	BMS1	83	70.753	ENSAOCG00000018088	bms1	54	66.258	Amphiprion_ocellaris
ENSG00000165733	BMS1	81	72.311	ENSAPEG00000014673	bms1	54	65.798	Amphiprion_percula
ENSG00000165733	BMS1	88	69.021	ENSATEG00000023465	bms1	52	68.354	Anabas_testudineus
ENSG00000165733	BMS1	95	72.414	ENSAPLG00000003759	BMS1	100	72.478	Anas_platyrhynchos
ENSG00000165733	BMS1	99	70.353	ENSACAG00000004537	-	99	69.755	Anolis_carolinensis
ENSG00000165733	BMS1	100	94.942	ENSANAG00000023432	BMS1	100	94.630	Aotus_nancymaae
ENSG00000165733	BMS1	87	68.571	ENSACLG00000001294	bms1	99	61.330	Astatotilapia_calliptera
ENSG00000165733	BMS1	82	73.103	ENSAMXG00000011236	bms1	51	66.199	Astyanax_mexicanus
ENSG00000165733	BMS1	100	89.019	ENSBTAG00000012878	BMS1	100	89.097	Bos_taurus
ENSG00000165733	BMS1	81	52.567	WBGene00022021	Y61A9LA.10	96	55.208	Caenorhabditis_elegans
ENSG00000165733	BMS1	100	95.175	ENSCJAG00000021705	BMS1	100	94.942	Callithrix_jacchus
ENSG00000165733	BMS1	99	89.945	ENSCAFG00000007114	BMS1	99	89.244	Canis_familiaris
ENSG00000165733	BMS1	99	89.945	ENSCAFG00020025282	BMS1	99	89.244	Canis_lupus_dingo
ENSG00000165733	BMS1	100	88.569	ENSCHIG00000023251	BMS1	100	88.647	Capra_hircus
ENSG00000165733	BMS1	99	82.578	ENSCAPG00000008652	BMS1	99	81.953	Cavia_aperea
ENSG00000165733	BMS1	99	86.562	ENSCPOG00000000502	BMS1	99	85.938	Cavia_porcellus
ENSG00000165733	BMS1	100	79.673	ENSCCAG00000024969	-	100	79.517	Cebus_capucinus
ENSG00000165733	BMS1	100	97.194	ENSCATG00000030625	-	100	97.194	Cercocebus_atys
ENSG00000165733	BMS1	90	73.154	ENSCATG00000008695	-	97	73.281	Cercocebus_atys
ENSG00000165733	BMS1	99	86.875	ENSCLAG00000002446	BMS1	99	86.328	Chinchilla_lanigera
ENSG00000165733	BMS1	100	97.350	ENSCSAG00000011118	BMS1	100	97.350	Chlorocebus_sabaeus
ENSG00000165733	BMS1	100	86.325	ENSCHOG00000011055	BMS1	100	86.636	Choloepus_hoffmanni
ENSG00000165733	BMS1	99	74.502	ENSCPBG00000025581	BMS1	99	72.872	Chrysemys_picta_bellii
ENSG00000165733	BMS1	81	55.479	ENSCING00000003181	-	97	56.934	Ciona_intestinalis
ENSG00000165733	BMS1	67	55.529	ENSCSAVG00000004113	-	82	60.831	Ciona_savignyi
ENSG00000165733	BMS1	100	97.272	ENSCANG00000011609	BMS1	100	97.272	Colobus_angolensis_palliatus
ENSG00000165733	BMS1	99	87.626	ENSCGRG00001019461	Bms1	99	86.381	Cricetulus_griseus_chok1gshd
ENSG00000165733	BMS1	99	87.558	ENSCGRG00000009016	Bms1	99	86.381	Cricetulus_griseus_crigri
ENSG00000165733	BMS1	82	73.474	ENSCSEG00000002469	bms1	50	68.882	Cynoglossus_semilaevis
ENSG00000165733	BMS1	80	75.362	ENSCVAG00000008371	bms1	97	67.901	Cyprinodon_variegatus
ENSG00000165733	BMS1	88	67.195	ENSDARG00000054154	bms1	99	61.115	Danio_rerio
ENSG00000165733	BMS1	100	89.164	ENSDNOG00000015761	BMS1	100	88.700	Dasypus_novemcinctus
ENSG00000165733	BMS1	99	87.910	ENSDORG00000002982	Bms1	99	87.754	Dipodomys_ordii
ENSG00000165733	BMS1	79	57.985	FBgn0036686	CG7728	92	58.435	Drosophila_melanogaster
ENSG00000165733	BMS1	85	83.929	ENSETEG00000009554	BMS1	91	83.929	Echinops_telfairi
ENSG00000165733	BMS1	99	89.339	ENSEASG00005006894	BMS1	99	89.728	Equus_asinus_asinus
ENSG00000165733	BMS1	99	90.039	ENSECAG00000001358	BMS1	99	89.572	Equus_caballus
ENSG00000165733	BMS1	89	66.793	ENSELUG00000001756	bms1	95	66.541	Esox_lucius
ENSG00000165733	BMS1	99	90.016	ENSFCAG00000011220	BMS1	99	90.094	Felis_catus
ENSG00000165733	BMS1	99	69.872	ENSFALG00000006882	BMS1	99	71.167	Ficedula_albicollis
ENSG00000165733	BMS1	99	85.234	ENSFDAG00000001422	BMS1	99	84.754	Fukomys_damarensis
ENSG00000165733	BMS1	85	69.628	ENSFHEG00000003367	bms1	97	66.923	Fundulus_heteroclitus
ENSG00000165733	BMS1	88	65.696	ENSGMOG00000000718	bms1	99	63.851	Gadus_morhua
ENSG00000165733	BMS1	99	71.297	ENSGALG00000002624	BMS1	99	72.167	Gallus_gallus
ENSG00000165733	BMS1	99	59.784	ENSGACG00000015334	bms1	88	66.290	Gasterosteus_aculeatus
ENSG00000165733	BMS1	99	74.395	ENSGAGG00000003467	BMS1	99	73.282	Gopherus_agassizii
ENSG00000165733	BMS1	87	68.571	ENSHBUG00000022628	bms1	99	61.378	Haplochromis_burtoni
ENSG00000165733	BMS1	99	86.027	ENSHGLG00000000477	BMS1	99	84.531	Heterocephalus_glaber_female
ENSG00000165733	BMS1	99	86.105	ENSHGLG00100002176	BMS1	99	84.609	Heterocephalus_glaber_male
ENSG00000165733	BMS1	89	67.805	ENSHCOG00000017604	bms1	98	66.154	Hippocampus_comes
ENSG00000165733	BMS1	55	63.738	ENSIPUG00000017855	bms1	99	60.790	Ictalurus_punctatus
ENSG00000165733	BMS1	99	88.828	ENSSTOG00000015063	BMS1	99	88.516	Ictidomys_tridecemlineatus
ENSG00000165733	BMS1	99	86.787	ENSJJAG00000017328	Bms1	99	86.396	Jaculus_jaculus
ENSG00000165733	BMS1	58	63.475	ENSKMAG00000021982	bms1	91	67.191	Kryptolebias_marmoratus
ENSG00000165733	BMS1	82	71.071	ENSLBEG00000028208	bms1	97	66.156	Labrus_bergylta
ENSG00000165733	BMS1	99	61.758	ENSLACG00000001600	BMS1	100	61.065	Latimeria_chalumnae
ENSG00000165733	BMS1	82	75.057	ENSLOCG00000012914	bms1	99	63.129	Lepisosteus_oculatus
ENSG00000165733	BMS1	99	87.773	ENSLAFG00000006250	BMS1	99	87.617	Loxodonta_africana
ENSG00000165733	BMS1	84	96.875	ENSMFAG00000037771	BMS1	100	96.875	Macaca_fascicularis
ENSG00000165733	BMS1	90	82.414	ENSMMUG00000007426	-	99	82.414	Macaca_mulatta
ENSG00000165733	BMS1	85	77.716	ENSMLEG00000029084	-	97	77.716	Mandrillus_leucophaeus
ENSG00000165733	BMS1	99	59.503	ENSMAMG00000020855	bms1	90	70.776	Mastacembelus_armatus
ENSG00000165733	BMS1	87	68.571	ENSMZEG00005005663	bms1	99	61.330	Maylandia_zebra
ENSG00000165733	BMS1	95	71.578	ENSMGAG00000001170	BMS1	99	71.890	Meleagris_gallopavo
ENSG00000165733	BMS1	99	86.936	ENSMAUG00000002195	Bms1	99	86.247	Mesocricetus_auratus
ENSG00000165733	BMS1	100	89.682	ENSMICG00000009977	BMS1	100	89.294	Microcebus_murinus
ENSG00000165733	BMS1	99	85.269	ENSMOCG00000002038	Bms1	99	85.269	Microtus_ochrogaster
ENSG00000165733	BMS1	85	67.992	ENSMMOG00000000977	bms1	97	65.370	Mola_mola
ENSG00000165733	BMS1	99	77.957	ENSMODG00000001177	BMS1	99	78.588	Monodelphis_domestica
ENSG00000165733	BMS1	96	64.000	ENSMALG00000009680	bms1	99	59.738	Monopterus_albus
ENSG00000165733	BMS1	70	94.660	MGP_CAROLIEiJ_G0028785	-	86	94.660	Mus_caroli
ENSG00000165733	BMS1	99	84.914	ENSMUSG00000030138	Bms1	99	85.070	Mus_musculus
ENSG00000165733	BMS1	99	85.202	MGP_PahariEiJ_G0022539	Bms1	99	85.280	Mus_pahari
ENSG00000165733	BMS1	99	85.148	MGP_SPRETEiJ_G0029816	Bms1	99	84.759	Mus_spretus
ENSG00000165733	BMS1	99	90.491	ENSMPUG00000017276	BMS1	99	89.867	Mustela_putorius_furo
ENSG00000165733	BMS1	100	88.733	ENSMLUG00000003260	BMS1	100	88.034	Myotis_lucifugus
ENSG00000165733	BMS1	100	96.415	ENSNLEG00000015791	BMS1	100	96.415	Nomascus_leucogenys
ENSG00000165733	BMS1	80	95.455	ENSOPRG00000005195	BMS1	81	95.455	Ochotona_princeps
ENSG00000165733	BMS1	99	85.625	ENSODEG00000005554	BMS1	99	84.844	Octodon_degus
ENSG00000165733	BMS1	89	68.949	ENSONIG00000007227	bms1	99	61.253	Oreochromis_niloticus
ENSG00000165733	BMS1	99	76.535	ENSOANG00000000662	-	99	76.146	Ornithorhynchus_anatinus
ENSG00000165733	BMS1	99	87.812	ENSOCUG00000005354	BMS1	99	87.812	Oryctolagus_cuniculus
ENSG00000165733	BMS1	87	68.775	ENSORLG00000014655	bms1	98	68.164	Oryzias_latipes
ENSG00000165733	BMS1	82	74.306	ENSORLG00020016246	bms1	92	68.506	Oryzias_latipes_hni
ENSG00000165733	BMS1	82	73.649	ENSORLG00015014183	bms1	92	68.506	Oryzias_latipes_hsok
ENSG00000165733	BMS1	87	68.590	ENSOMEG00000015042	bms1	96	66.992	Oryzias_melastigma
ENSG00000165733	BMS1	99	90.303	ENSOGAG00000006511	BMS1	99	89.527	Otolemur_garnettii
ENSG00000165733	BMS1	100	88.450	ENSOARG00000003900	BMS1	100	88.527	Ovis_aries
ENSG00000165733	BMS1	100	95.791	ENSPPAG00000027837	BMS1	100	95.791	Pan_paniscus
ENSG00000165733	BMS1	99	90.156	ENSPPRG00000001311	BMS1	99	90.234	Panthera_pardus
ENSG00000165733	BMS1	99	87.978	ENSPTIG00000009652	BMS1	99	88.056	Panthera_tigris_altaica
ENSG00000165733	BMS1	100	99.532	ENSPTRG00000002441	BMS1	100	99.532	Pan_troglodytes
ENSG00000165733	BMS1	99	71.123	ENSPSIG00000006481	BMS1	99	72.419	Pelodiscus_sinensis
ENSG00000165733	BMS1	99	79.141	ENSPEMG00000022467	Bms1	99	79.235	Peromyscus_maniculatus_bairdii
ENSG00000165733	BMS1	95	92.617	ENSPCIG00000001339	BMS1	99	86.761	Phascolarctos_cinereus
ENSG00000165733	BMS1	80	74.384	ENSPFOG00000015180	bms1	96	66.032	Poecilia_formosa
ENSG00000165733	BMS1	79	74.631	ENSPMEG00000023176	bms1	91	66.032	Poecilia_mexicana
ENSG00000165733	BMS1	85	67.258	ENSPREG00000002695	bms1	95	66.667	Poecilia_reticulata
ENSG00000165733	BMS1	61	98.069	ENSPPYG00000002836	-	99	98.069	Pongo_abelii
ENSG00000165733	BMS1	73	93.878	ENSPCAG00000014528	BMS1	73	93.878	Procavia_capensis
ENSG00000165733	BMS1	95	86.062	ENSPCOG00000023834	-	99	85.656	Propithecus_coquereli
ENSG00000165733	BMS1	100	86.838	ENSPVAG00000000725	BMS1	100	87.227	Pteropus_vampyrus
ENSG00000165733	BMS1	97	62.776	ENSPNYG00000018866	bms1	87	66.667	Pundamilia_nyererei
ENSG00000165733	BMS1	82	82.436	ENSRNOG00000006576	Bms1	100	83.381	Rattus_norvegicus
ENSG00000165733	BMS1	100	95.323	ENSRROG00000040101	BMS1	100	95.323	Rhinopithecus_roxellana
ENSG00000165733	BMS1	71	46.781	YPL217C	-	79	48.826	Saccharomyces_cerevisiae
ENSG00000165733	BMS1	100	95.175	ENSSBOG00000035778	BMS1	100	95.253	Saimiri_boliviensis_boliviensis
ENSG00000165733	BMS1	99	78.067	ENSSHAG00000005062	BMS1	99	78.298	Sarcophilus_harrisii
ENSG00000165733	BMS1	99	62.008	ENSSFOG00015022313	bms1	99	60.890	Scleropages_formosus
ENSG00000165733	BMS1	82	73.733	ENSSMAG00000019966	bms1	53	65.961	Scophthalmus_maximus
ENSG00000165733	BMS1	89	68.932	ENSSDUG00000016875	bms1	90	58.306	Seriola_dumerili
ENSG00000165733	BMS1	83	70.000	ENSSLDG00000015199	bms1	53	66.922	Seriola_lalandi_dorsalis
ENSG00000165733	BMS1	70	76.398	ENSSARG00000014407	BMS1	100	75.615	Sorex_araneus
ENSG00000165733	BMS1	99	73.027	ENSSPUG00000014454	BMS1	99	73.206	Sphenodon_punctatus
ENSG00000165733	BMS1	99	89.400	ENSSSCG00000010198	BMS1	99	89.556	Sus_scrofa
ENSG00000165733	BMS1	99	70.936	ENSTGUG00000006302	-	99	71.232	Taeniopygia_guttata
ENSG00000165733	BMS1	86	64.943	ENSTRUG00000008028	bms1	97	64.173	Takifugu_rubripes
ENSG00000165733	BMS1	99	59.814	ENSTNIG00000006216	bms1	90	65.135	Tetraodon_nigroviridis
ENSG00000165733	BMS1	60	93.846	ENSTBEG00000001673	-	63	93.846	Tupaia_belangeri
ENSG00000165733	BMS1	100	87.607	ENSTTRG00000007983	BMS1	100	86.984	Tursiops_truncatus
ENSG00000165733	BMS1	99	90.250	ENSUAMG00000023996	BMS1	99	90.640	Ursus_americanus
ENSG00000165733	BMS1	99	90.094	ENSUMAG00000016523	BMS1	99	90.484	Ursus_maritimus
ENSG00000165733	BMS1	88	83.363	ENSVPAG00000007477	BMS1	100	84.331	Vicugna_pacos
ENSG00000165733	BMS1	99	89.945	ENSVVUG00000021305	BMS1	99	89.244	Vulpes_vulpes
ENSG00000165733	BMS1	98	65.197	ENSXETG00000008158	bms1	99	65.710	Xenopus_tropicalis
ENSG00000165733	BMS1	85	67.360	ENSXCOG00000000506	bms1	96	75.366	Xiphophorus_couchianus
ENSG00000165733	BMS1	85	67.149	ENSXMAG00000014236	bms1	97	65.637	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005525	GTP binding	21873635.	IBA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005730	nucleolus	-	ISS	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0030686	90S preribosome	21873635.	IBA	Component
GO:0034511	U3 snoRNA binding	21873635.	IBA	Function