EuRBPDB

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  • Basic Information
  • Cancer Related Information

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000166508 (Gene tree)
Gene ID
4176
Gene Symbol
MCM7
Alias
CDC47|PPP1R104|MCM2
Full Name
minichromosome maintenance complex component 7
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
9,213 bases
Position
chr7:100,092,728-100,101,940
Accession
6950
RBP type
non-canonical RBP
Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
19106611Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells.Cell Cycle2009 Jan 1Liu P-
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000465688MCM7-206481--- (aa)--
ENST00000489841MCM7-2102515--- (aa)--
ENST00000463722MCM7-2051327--- (aa)--
ENST00000343023MCM7-2021968-ENSP00000344006389 (aa)-P33993
ENST00000303887MCM7-2012957-ENSP00000307288719 (aa)-P33993
ENST00000425308MCM7-2041497-ENSP00000411295183 (aa)-C9J8M6
ENST00000621318MCM7-2133084-ENSP00000483795543 (aa)-P33993
ENST00000493352MCM7-212533--- (aa)--
ENST00000354230MCM7-2032975XM_005250348ENSP00000346171543 (aa)XP_005250405P33993
ENST00000465738MCM7-207448--- (aa)--
ENST00000467516MCM7-208776--- (aa)--
ENST00000491245MCM7-211648-ENSP0000044590483 (aa)-H0YH42
ENST00000485286MCM7-2092900--- (aa)--
Gene Model
Click here to download ENSG00000166508's gene model file
Pathways
Pathway IDPathway NameSource
hsa03030DNA replicationKEGG
hsa04110Cell cycleKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000166508Lung Diseases, Interstitial1.0229710E-006-
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000166508rs22613607100095370TLung function (FEV1/FVC)30804560[0.016-0.027] unit increase0.0219EFO_0004713
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000166508's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000166508MCM78436.290WBGene00003157mcm-57135.120Caenorhabditis_elegans
ENSG00000166508MCM710070.956FBgn0020633Mcm710067.361Drosophila_melanogaster
ENSG00000166508MCM78933.089FBgn0017577Mcm58633.382Drosophila_melanogaster
ENSG00000166508MCM78535.882ENSG00000076003MCM66735.842Homo_sapiens
ENSG00000166508MCM77640.257ENSG00000112118MCM36837.324Homo_sapiens
ENSG00000166508MCM78731.853ENSG00000100297MCM58431.853Homo_sapiens
ENSG00000166508MCM710094.291ENSMUSG00000029730Mcm710093.636Mus_musculus
ENSG00000166508MCM77640.043ENSMUSG00000041859Mcm36837.367Mus_musculus
ENSG00000166508MCM78934.483YGL201C7133.516Saccharomyces_cerevisiae
ENSG00000166508MCM78731.825YLR274WMCM58532.544Saccharomyces_cerevisiae
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000082G1/S transition of mitotic cell cycle-TASProcess
GO:0000784nuclear chromosome, telomeric region19135898.HDAComponent
GO:0000785chromatin8798650.TASComponent
GO:0003677DNA binding15538388.TASFunction
GO:0003697single-stranded DNA binding-IEAFunction
GO:0004003ATP-dependent DNA helicase activity9305914.IDAFunction
GO:0005515protein binding9705868.10518787.12364596.15232106.15538388.15654075.16289477.16438930.16899510.17296731.17310990.17314511.19150984.22540012.23397142.23764002.24299456.25036637.25416956.26496610.26871637.28191891.IPIFunction
GO:0005524ATP binding-IEAFunction
GO:0005634nucleus21383955.IDAComponent
GO:0005654nucleoplasm-IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005730nucleolus21383955.IDAComponent
GO:0005829cytosol-IDAComponent
GO:0006260DNA replication-TASProcess
GO:0006268DNA unwinding involved in DNA replication-IEAProcess
GO:0006270DNA replication initiation-IEAProcess
GO:0006974cellular response to DNA damage stimulus15538388.IMPProcess
GO:0008283cell proliferation-IEAProcess
GO:0016020membrane19946888.HDAComponent
GO:0042325regulation of phosphorylation15538388.IMPProcess
GO:0042493response to drug-IEAProcess
GO:0042555MCM complex17296731.IDAComponent
GO:0042555MCM complex15538388.IMPComponent
GO:0071364cellular response to epidermal growth factor stimulus-IEAProcess
GO:0071466cellular response to xenobiotic stimulus-IEAProcess

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
22456526Prognostic significance of MCM7 expression in the bronchial brushings of patients with non-small cell lung cancer (NSCLC).Lung Cancer2012 JulLiu YZdoi: 10.1016/j.lungcan.2012.03.001
24166506Depletion of minichromosome maintenance protein 7 inhibits glioblastoma multiforme tumor growth in vivo.Oncogene2014 Sep 25Erkan EPdoi: 10.1038/onc.2013.423
17094475Immunohistochemical evaluation of minichromosome maintenance protein 7 in astrocytoma grading.Anticancer Res2006 Sep-OctFacoetti A-
28498460MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.Oncol Rep2017 JunQiu YTdoi: 10.3892/or.2017.5614
18636144Minichromosome maintenance protein 7 in colorectal cancer: implication of prognostic significance.Int J Oncol2008 AugNishihara K-
23764002Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.Cancer Cell2013 Jun 10Huang THdoi: 10.1016/j.ccr.2013.04.027.
14678972Comparative analysis of cervical cancer in women and in a human papillomavirus-transgenic mouse model: identification of minichromosome maintenance protein 7 as an informative biomarker for human cervical cancer.Cancer Res2003 Dec 1Brake T-
24324072Comparison of minichromosome maintenance proteins (MCM-3, MCM-7) and metallothioneins (MT-I/II, MT-III) expression in relation to clinicopathological data in ovarian cancer.Anticancer Res2013 DecKobierzycki C-
21619671Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.Mol Cancer2011 May 28Toyokawa Gdoi: 10.1186/1476-4598-10-65.
21076460Minichromosome maintenance protein 7 as a potential prognostic factor for progression-free survival in high-grade serous carcinomas of the ovary.Mod Pathol2011 FebOta Tdoi: 10.1038/modpathol.2010.202
23201130Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer.Am J Pathol2013 FebFristrup Ndoi: 10.1016/j.ajpath.2012.10.017
26966728Upregulated expression of BCL2, MCM7, and CCNE1 indicate cisplatin-resistance in the set of two human bladder cancer cell lines: T24 cisplatin sensitive and T24R2 cisplatin resistant bladder cancer cell lines.Investig Clin Urol2016 JanKim SHdoi: 10.4111/icu.2016.57.1.63
25075101Minichromosome maintenance protein 7 is a risk factor for recurrence in patients with Dukes C colorectal cancer.Anticancer Res2014 AugIshibashi Y-
24647462MCM7 serves as a prognostic marker in diffuse-type gastric adenocarcinoma and siRNA-mediated knockdown suppresses its oncogenic function.Oncol Rep2014 MayKang Wdoi: 10.3892/or.2014.3094
16247466MCM7 amplification and overexpression are associated with prostate cancer progression.Oncogene2006 Feb 16Ren B-
27797825MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.Carcinogenesis2017 JanLo Sardo Fdoi: 10.1093/carcin/bgw110
28059478Amplified 7q21-22 gene MCM7 and its intronic miR-25 suppress COL1A2 associated genes to sustain intestinal gastric cancer features.Mol Carcinog2017 JunTamilzhalagan Sdoi: 10.1002/mc.22614
28182015MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma.Cell Death Dis2017 Feb 9Qu Kdoi: 10.1038/cddis.2016.352.
28628830Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation.Biomed Pharmacother2017 SepGuan YBdoi: 10.1016/j.biopha.2017.06.024

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr7100099667SilentnovelI66I0.16
BLCAchr71001016775'UTRnovel0.39
BLCAchr7100095389Missense_MutationnovelM559I0.59
BLCAchr7100099708Missense_MutationnovelD53H0.3
BLCAchr7100099723SilentnovelL48L0.34
BLCAchr7100097859SilentnovelT320T0.06
BLCAchr7100098287Missense_MutationnovelD242N0.55
BLCAchr7100099256Intronrs7684525470.46
BLCAchr7100097847SilentNAL324L0.08
BLCAchr71001016685'UTRnovel0.16
BLCAchr7100093378SilentnovelV624V0.36
BLCAchr7100097632Nonsense_Mutationrs758325786R367*0.05
BLCAchr7100097901Missense_MutationnovelM306I0.16
BLCAchr7100093348Missense_MutationnovelI634M0.16
BLCAchr7100093572IntronNA0.19
BLCAchr7100099675Missense_MutationnovelD64N0.31
BLCAchr7100095789Missense_Mutationrs762150483R527Q0.27
BLCAchr7100097632Nonsense_Mutationrs758325786R367*0.34
BRCAchr7100097337Nonsense_Mutationrs774774371Q389*0.09
BRCAchr7100099298Missense_MutationNAA128T0.41
BRCAchr7100099651Missense_Mutationrs374121810R72C0.24
BRCAchr7100097715Nonsense_MutationNAS339*0.22
BRCAchr7100099315Missense_MutationnovelP122R0.15
BRCAchr7100094011Intronnovel0.15
BRCAchr7100099274Splice_Regionnovel0.1
BRCAchr7100099187Missense_MutationnovelG140R0.09
BRCAchr7100099114Missense_Mutationrs755514827R164H0.47
BRCAchr71000928773'UTRnovel0.15
BRCAchr7100097327Missense_MutationNAS392L0.26
BRCAchr71000928353'UTRnovel0.29
BRCAchr7100098617Frame_Shift_DelnovelR228Dfs*80.04
BRCAchr71000929183'UTRnovel0.04
BRCAchr7100097848Frame_Shift_InsnovelL324Pfs*280.18
BRCAchr7100095775Missense_Mutationrs775586840R532W0.19
BRCAchr7100093085SilentNAV669V0.24
BRCAchr7100093381Missense_MutationnovelD623E0.08
CESCchr71001013335'UTRnovel0.66
CESCchr7100096140Nonsense_MutationNAS410*0.34
CESCchr7100097632Nonsense_Mutationrs758325786R367*0.27
CESCchr71001013025'UTRnovel0.19
CESCchr7100099370Nonsense_MutationNAE104*0.17
CESCchr71001013025'UTRnovel0.35
COADchr7100092973Missense_MutationnovelW707R0.28
COADchr7100100034Missense_MutationnovelF31L0.09
COADchr71001016695'UTRnovel0.42
COADchr7100095944SilentNAL475L0.29
COADchr7100092990Missense_MutationnovelY701C0.13
COADchr7100095775Missense_Mutationrs775586840R532W0.35
COADchr7100098625Missense_Mutationrs752275987R225W0.65
COADchr7100095793Missense_Mutationrs765971073D526N0.32
COADchr7100098194Missense_Mutationrs778913504V273I0.38
COADchr7100097881Missense_MutationNAE313A0.28
COADchr7100099723Missense_MutationNAL48M0.5
COADchr7100094340Missense_Mutationrs755556849R561C0.25
COADchr7100097732Silentrs146340949Y333Y0.11
COADchr7100099313Frame_Shift_DelNAQ123Rfs*260.47
COADchr7100094250Missense_MutationNAE591K0.19
COADchr7100095422Frame_Shift_DelNAS549Pfs*80.36
COADchr7100096151Silentrs775965154G406G0.26
COADchr7100094266Silentrs762734756Y585Y0.25
COADchr7100097914Missense_Mutationrs767546167R302Q0.34
DLBCchr7100100275Intronnovel0.2
DLBCchr7100098678Missense_MutationnovelP207L0.27
DLBCchr71001017045'UTRnovel0.18
ESCAchr71001014035'UTRnovel0.11
ESCAchr7100094029Intronrs726318270.38
GBMchr7100096073SilentNAG432G0.24
GBMchr7100094266Silentrs762734756Y585Y0.28
GBMchr7100095840Missense_MutationnovelA510E0.09
GBMchr7100097304Missense_Mutationrs751951140R400C0.25
GBMchr7100099650Missense_MutationnovelR72H0.46
GBMchr7100092992Missense_MutationnovelE700D0.07
GBMchr7100093580Intronnovel0.35
GBMchr7100096006Missense_Mutationrs750263017R455C0.08
GBMchr7100094211SilentnovelR604R0.03
GBMchr71000928343'UTRnovel0.17
GBMchr7100092983Missense_MutationnovelE703D0.08
HNSCchr7100094265Missense_Mutationrs772794463V586M0.14
HNSCchr7100095928Missense_Mutationrs770263756R481C0.11
HNSCchr7100095879Missense_Mutationrs759076249P497R0.33
HNSCchr7100098686SilentnovelI204I0.21
HNSCchr7100099142Missense_MutationnovelD155H0.06
HNSCchr7100099352Missense_Mutationrs752747070E110K0.18
HNSCchr71001016975'UTRnovel0.12
HNSCchr71001016105'UTRnovel0.21
HNSCchr7100097319Missense_MutationnovelD395H0.19
HNSCchr71001018595'UTRnovel0.28
HNSCchr7100099127SilentnovelL160L0.39
KIRCchr7100099595Missense_MutationNAE90D0.18
KIRCchr7100097653Missense_Mutationrs781137780G360R0.39
KIRCchr7100099080SilentnovelP175P0.34
KIRCchr7100095912Missense_MutationNAA486D0.1
LGGchr7100099619SilentnovelQ82Q0.38
LGGchr7100092971Nonsense_MutationnovelW707*0.53
LGGchr7100097654Silentrs146058965V359V0.05
LGGchr7100099387Missense_MutationnovelV98G0.44
LIHCchr7100094313Nonsense_MutationnovelQ570*0.07
LIHCchr7100100095Splice_Siters762955038X11_splice0.42
LIHCchr7100099686Missense_MutationNAP60R0.54
LIHCchr7100097379Missense_MutationNAI375V0.22
LIHCchr7100095986SilentnovelV461V0.1
LIHCchr7100096078Missense_MutationNAG431C0.07
LIHCchr7100099686Missense_MutationNAP60R0.15
LIHCchr7100097743Missense_MutationnovelE330Q0.58
LIHCchr71001016955'UTRnovel0.51
LIHCchr71001014135'UTRnovel0.08
LUADchr7100093770Intronrs3720155560.13
LUADchr7100099622SilentnovelV81V0.14
LUADchr7100099147Missense_Mutationrs748597030R153Q0.18
LUADchr7100098209Missense_MutationNAG268R0.23
LUADchr7100100014Missense_MutationNAL37F0.19
LUADchr71001013585'UTRnovel0.48
LUADchr7100099082Frame_Shift_InsnovelP175Tfs*110.29
LUADchr7100098716Splice_SiteNAX195_splice0.39
LUADchr7100095974Missense_MutationnovelQ465H0.07
LUSCchr7100094260Silentrs761402052E587E0.38
LUSCchr7100093825Intronnovel0.17
LUSCchr71001013805'UTRnovel0.19
LUSCchr7100099166Missense_Mutationrs549764255R147C0.44
LUSCchr71001016865'UTRnovel0.1
LUSCchr71001013025'UTRnovel0.29
LUSCchr7100094036IntronNA0.28
LUSCchr7100097656Missense_MutationNAV359F0.39
OVchr7100093602Intronnovel0.05
OVchr71000928273'UTRnovel0.12
OVchr7100093637Intronnovel0.17
OVchr7100099262Intronnovel0.28
OVchr7100092961Missense_MutationnovelA711P0.07
OVchr7100093338Nonsense_MutationnovelE638*0.05
OVchr7100095978Nonsense_MutationnovelQ464delinsPVFTPF*I*0.04
OVchr7100098142Missense_MutationnovelQ290L0.06
OVchr7100094210Missense_MutationnovelR604Q0.06
OVchr7100098142Missense_MutationnovelQ290L0.13
OVchr71001016905'UTRnovel0.33
PAADchr7100094171Splice_SitenovelX616_splice0.16
PRADchr71001016865'UTRnovel0.1
PRADchr7100093075Nonsense_Mutationrs532820415R673*0.23
READchr7100099749Missense_MutationNAR39Q0.42
READchr7100093061Missense_MutationnovelF677L0.52
READchr7100097732Silentrs146340949Y333Y0.46
SARCchr7100099737Missense_Mutationrs767495591R43L0.13
SKCMchr7100099736SilentNAR43R0.33
SKCMchr7100095458SilentnovelH536H0.17
SKCMchr7100095459Missense_MutationnovelH536L0.15
SKCMchr7100098598Missense_MutationnovelE234K0.34
SKCMchr7100098599SilentnovelQ233Q0.34
SKCMchr7100093771Intronnovel0.21
SKCMchr7100095959Silentrs764119522A470A0.22
SKCMchr7100099694SilentNAE57E0.28
SKCMchr71001014035'UTRnovel0.1
SKCMchr71001017085'UTRnovel0.22
SKCMchr7100093565Intronrs7706326910.5
SKCMchr7100099157Missense_Mutationrs531476711R150W0.33
SKCMchr7100099323SilentNAV119V0.14
SKCMchr71000928813'UTRnovel0.19
SKCMchr7100098198Silentrs767764393V271V0.32
SKCMchr7100093305Missense_MutationNAG649R0.13
SKCMchr7100095422SilentnovelP548P0.38
SKCMchr7100096028Silentrs150968866F447F0.19
SKCMchr7100095818Silentrs149943121L517L0.25
SKCMchr7100095419SilentNAS549S0.42
SKCMchr71001014035'UTRnovel0.39
SKCMchr7100099722Missense_MutationnovelL48P0.23
SKCMchr7100098156SilentnovelF285F0.31
SKCMchr71001014035'UTRnovel0.29
STADchr7100097345Missense_MutationNAA386D0.21
STADchr7100098643Missense_MutationnovelR219W0.12
STADchr7100094314SilentnovelK569K0.2
STADchr7100093004Silentrs139468339A696A0.11
STADchr71000928073'UTRnovel0.33
STADchr7100094282Missense_MutationnovelY580C0.1
STADchr7100100054Missense_MutationnovelD24G0.11
STADchr7100095846Missense_MutationNAP508L0.11
STADchr7100097737Missense_MutationNAF332V0.19
STADchr7100099345Missense_MutationNAR112Q0.12
STADchr7100094026Intronnovel0.25
STADchr7100094069Intronrs7538799950.21
STADchr7100097731Missense_Mutationrs781082655E334K0.21
UCECchr7100094339Missense_Mutationrs752169854R561H0.38
UCECchr7100095790Nonsense_Mutationrs76705400R527*0.45
UCECchr7100096028Silentrs150968866F447F0.47
UCECchr7100093368Missense_MutationnovelE628Q0.03
UCECchr7100094206SilentnovelT605T0.18
UCECchr7100098249SilentNAT254T0.44
UCECchr7100093770Intronrs3720155560.48
UCECchr7100093825Intronrs7797056830.25
UCECchr7100099639Missense_MutationnovelL76I0.23
UCECchr7100097710Missense_Mutationrs749928037A341T0.48
UCECchr7100099749Missense_MutationNAR39Q0.19
UCECchr7100098250Missense_Mutationrs200587772T254M0.08
UCECchr7100097705SilentnovelP342P0.14
UCECchr7100097320SilentnovelI394I0.31
UCECchr71001016615'UTRnovel0.37
UCECchr7100099630Missense_MutationnovelD79N0.39
UCECchr7100098155Nonsense_MutationNAR286*0.16
UCECchr7100095989Missense_MutationnovelE460D0.11
UCECchr7100095422Frame_Shift_DelNAS549Pfs*80.45
UCECchr7100095873Missense_Mutationrs770587656R499H0.34
UCECchr7100098195Silentrs749861268S272S0.39
UCECchr7100098665SilentnovelC211C0.44
UCECchr7100093074Missense_Mutationrs368686483R673Q0.55
UCECchr7100093780Intronnovel0.32
UCECchr7100099342Missense_MutationNAS113N0.4
UCECchr7100095772Splice_SitenovelX532_splice0.43
UCECchr71001016065'UTRnovel0.26
UCECchr7100093018Missense_Mutationrs573331867A692T0.39
UCECchr7100094021Intronnovel0.36
UCECchr7100096130SilentnovelG413G0.37
UCECchr7100097617SilentnovelR372R0.4
UCECchr7100099382Missense_MutationnovelD100N0.36
UCECchr7100095422Frame_Shift_DelNAS549Pfs*80.18
UCECchr7100092975Missense_MutationnovelV706A0.3
UCECchr7100099311Missense_MutationnovelQ123H0.2
UCECchr7100093626Intronrs7764977590.43
UCECchr71001015445'UTRnovel0.67
UCECchr71001014125'UTRnovel0.15
UCECchr7100097744Missense_MutationNAE329D0.22
UCECchr7100099650Missense_MutationnovelR72H0.21
UCECchr7100097299Splice_SitenovelX401_splice0.37
UCECchr7100097652Missense_Mutationrs754886665G360E0.11
UCECchr7100093044Missense_Mutationrs761764851R683H0.5
UCECchr7100094266Silentrs762734756Y585Y0.35
UCECchr7100099703Silentrs756393754D54D0.18
UCECchr7100095873Missense_Mutationrs770587656R499H0.42
UCSchr7100099148Missense_Mutationrs150260409R153W0.05

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ACCDEL0.05560.12261
DLBCAMP0.29170.13215
LIHCDEL0.06220.24831
PAADDEL0.0380.049388
PRADAMP0.14020.012709
TGCTAMP0.63330.035574
THCADEL0.0020.27619

Survival Analysis
CancerP-value Q-value
THYM0.0034

Kaplan-Meier Survival Analysis

STAD0.046

Kaplan-Meier Survival Analysis

SARC0.026

Kaplan-Meier Survival Analysis

MESO0.00017

Kaplan-Meier Survival Analysis

ACC0.00015

Kaplan-Meier Survival Analysis

SKCM0.028

Kaplan-Meier Survival Analysis

PRAD0.011

Kaplan-Meier Survival Analysis

LUSC0.0045

Kaplan-Meier Survival Analysis

BRCA0.046

Kaplan-Meier Survival Analysis

CESC0.033

Kaplan-Meier Survival Analysis

READ0.028

Kaplan-Meier Survival Analysis

KICH0.0074

Kaplan-Meier Survival Analysis

UCEC0.035

Kaplan-Meier Survival Analysis

LIHC0.00015

Kaplan-Meier Survival Analysis

DLBC0.0061

Kaplan-Meier Survival Analysis

LGG0.013

Kaplan-Meier Survival Analysis

CHOL0.029

Kaplan-Meier Survival Analysis

THCA0.02

Kaplan-Meier Survival Analysis

LUAD0.0026

Kaplan-Meier Survival Analysis

Drugs

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Input Drug :


Input Cell Line :


Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742


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