Protein ID | Domain | Pfam ID | E-value | Domain number | Total number |
---|---|---|---|---|---|
ENSP00000361725 | Endonuclease_NS | PF01223.23 | 8.3e-62 | 1 | 1 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000372642 | ENDOG-201 | 1172 | XM_011518347 | ENSP00000361725 | 297 (aa) | XP_011516649 | Q14249 |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa04210 | Apoptosis | KEGG |
Ensembl ID | Gene Symbol | Coverage | Identiy | Paralog | Gene Symbol | Coverage | Identiy |
---|---|---|---|---|---|---|---|
ENSG00000167136 | ENDOG | 81 | 38.115 | ENSG00000157036 | EXOG | 82 | 42.581 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000167136 | ENDOG | 98 | 64.333 | ENSAPOG00000001316 | endog | 98 | 65.646 | Acanthochromis_polyacanthus |
ENSG00000167136 | ENDOG | 77 | 90.351 | ENSAMEG00000015801 | ENDOG | 100 | 90.351 | Ailuropoda_melanoleuca |
ENSG00000167136 | ENDOG | 98 | 63.758 | ENSACIG00000007086 | endog | 99 | 63.051 | Amphilophus_citrinellus |
ENSG00000167136 | ENDOG | 80 | 72.269 | ENSAOCG00000013970 | endog | 99 | 64.746 | Amphiprion_ocellaris |
ENSG00000167136 | ENDOG | 83 | 66.802 | ENSAPEG00000024202 | endog | 99 | 61.279 | Amphiprion_percula |
ENSG00000167136 | ENDOG | 99 | 67.224 | ENSATEG00000015467 | endog | 99 | 66.107 | Anabas_testudineus |
ENSG00000167136 | ENDOG | 70 | 80.288 | ENSAPLG00000004952 | ENDOG | 100 | 80.288 | Anas_platyrhynchos |
ENSG00000167136 | ENDOG | 97 | 65.449 | ENSACLG00000009792 | endog | 98 | 64.430 | Astatotilapia_calliptera |
ENSG00000167136 | ENDOG | 87 | 70.260 | ENSAMXG00000032808 | endog | 98 | 63.725 | Astyanax_mexicanus |
ENSG00000167136 | ENDOG | 80 | 89.167 | ENSBTAG00000012484 | ENDOG | 79 | 89.167 | Bos_taurus |
ENSG00000167136 | ENDOG | 74 | 49.327 | WBGene00000787 | cps-6 | 70 | 49.770 | Caenorhabditis_elegans |
ENSG00000167136 | ENDOG | 100 | 94.649 | ENSCJAG00000020220 | ENDOG | 100 | 93.980 | Callithrix_jacchus |
ENSG00000167136 | ENDOG | 93 | 94.286 | ENSCAFG00000020036 | ENDOG | 100 | 93.000 | Canis_familiaris |
ENSG00000167136 | ENDOG | 93 | 94.286 | ENSCAFG00020022974 | ENDOG | 100 | 93.000 | Canis_lupus_dingo |
ENSG00000167136 | ENDOG | 93 | 92.832 | ENSCHIG00000020781 | ENDOG | 100 | 91.304 | Capra_hircus |
ENSG00000167136 | ENDOG | 100 | 91.304 | ENSCPOG00000025286 | ENDOG | 100 | 90.635 | Cavia_porcellus |
ENSG00000167136 | ENDOG | 100 | 87.625 | ENSCCAG00000028186 | ENDOG | 100 | 86.622 | Cebus_capucinus |
ENSG00000167136 | ENDOG | 100 | 96.321 | ENSCATG00000037516 | ENDOG | 100 | 96.321 | Cercocebus_atys |
ENSG00000167136 | ENDOG | 80 | 95.378 | ENSCLAG00000006402 | ENDOG | 96 | 95.745 | Chinchilla_lanigera |
ENSG00000167136 | ENDOG | 100 | 96.990 | ENSCSAG00000014436 | ENDOG | 100 | 96.990 | Chlorocebus_sabaeus |
ENSG00000167136 | ENDOG | 89 | 80.682 | ENSCPBG00000023353 | ENDOG | 97 | 76.531 | Chrysemys_picta_bellii |
ENSG00000167136 | ENDOG | 77 | 52.586 | ENSCING00000014331 | - | 84 | 53.333 | Ciona_intestinalis |
ENSG00000167136 | ENDOG | 100 | 87.919 | ENSCGRG00001024006 | Endog | 100 | 86.532 | Cricetulus_griseus_chok1gshd |
ENSG00000167136 | ENDOG | 61 | 96.111 | ENSCGRG00000012823 | Endog | 88 | 91.667 | Cricetulus_griseus_crigri |
ENSG00000167136 | ENDOG | 87 | 70.992 | ENSCSEG00000008066 | endog | 98 | 65.424 | Cynoglossus_semilaevis |
ENSG00000167136 | ENDOG | 97 | 66.102 | ENSCVAG00000010105 | endog | 98 | 65.424 | Cyprinodon_variegatus |
ENSG00000167136 | ENDOG | 97 | 67.000 | ENSDARG00000058865 | endog | 98 | 65.667 | Danio_rerio |
ENSG00000167136 | ENDOG | 93 | 93.141 | ENSDNOG00000031222 | - | 99 | 91.246 | Dasypus_novemcinctus |
ENSG00000167136 | ENDOG | 62 | 91.848 | ENSDNOG00000024568 | - | 80 | 89.216 | Dasypus_novemcinctus |
ENSG00000167136 | ENDOG | 89 | 83.032 | ENSDORG00000028893 | Endog | 91 | 96.429 | Dipodomys_ordii |
ENSG00000167136 | ENDOG | 85 | 30.147 | FBgn0037857 | Tengl4 | 58 | 32.127 | Drosophila_melanogaster |
ENSG00000167136 | ENDOG | 73 | 46.154 | FBgn0052463 | Tengl2 | 69 | 46.154 | Drosophila_melanogaster |
ENSG00000167136 | ENDOG | 95 | 49.495 | FBgn0033690 | EndoG | 96 | 47.987 | Drosophila_melanogaster |
ENSG00000167136 | ENDOG | 100 | 92.308 | ENSEASG00005007720 | ENDOG | 100 | 92.642 | Equus_asinus_asinus |
ENSG00000167136 | ENDOG | 100 | 93.311 | ENSECAG00000009809 | ENDOG | 100 | 92.642 | Equus_caballus |
ENSG00000167136 | ENDOG | 98 | 65.132 | ENSELUG00000015964 | endog | 96 | 63.455 | Esox_lucius |
ENSG00000167136 | ENDOG | 89 | 94.697 | ENSFCAG00000005859 | ENDOG | 100 | 93.289 | Felis_catus |
ENSG00000167136 | ENDOG | 85 | 80.080 | ENSFALG00000001421 | ENDOG | 94 | 82.128 | Ficedula_albicollis |
ENSG00000167136 | ENDOG | 91 | 68.478 | ENSFHEG00000007793 | endog | 98 | 66.330 | Fundulus_heteroclitus |
ENSG00000167136 | ENDOG | 59 | 72.472 | ENSGMOG00000004330 | endog | 94 | 73.214 | Gadus_morhua |
ENSG00000167136 | ENDOG | 77 | 74.672 | ENSGAFG00000002401 | endog | 99 | 74.672 | Gambusia_affinis |
ENSG00000167136 | ENDOG | 99 | 65.789 | ENSGACG00000010633 | endog | 99 | 71.304 | Gasterosteus_aculeatus |
ENSG00000167136 | ENDOG | 77 | 81.739 | ENSGAGG00000021110 | ENDOG | 97 | 74.150 | Gopherus_agassizii |
ENSG00000167136 | ENDOG | 100 | 98.990 | ENSGGOG00000014224 | ENDOG | 100 | 98.990 | Gorilla_gorilla |
ENSG00000167136 | ENDOG | 97 | 64.189 | ENSHBUG00000003699 | endog | 98 | 63.423 | Haplochromis_burtoni |
ENSG00000167136 | ENDOG | 93 | 91.398 | ENSHGLG00000011977 | ENDOG | 100 | 90.635 | Heterocephalus_glaber_female |
ENSG00000167136 | ENDOG | 58 | 84.000 | ENSHGLG00100018337 | ENDOG | 88 | 84.000 | Heterocephalus_glaber_male |
ENSG00000167136 | ENDOG | 98 | 64.548 | ENSHCOG00000020736 | endog | 99 | 63.514 | Hippocampus_comes |
ENSG00000167136 | ENDOG | 99 | 67.224 | ENSIPUG00000009770 | endog | 97 | 66.221 | Ictalurus_punctatus |
ENSG00000167136 | ENDOG | 93 | 80.142 | ENSSTOG00000022690 | ENDOG | 100 | 81.034 | Ictidomys_tridecemlineatus |
ENSG00000167136 | ENDOG | 90 | 67.518 | ENSKMAG00000005240 | endog | 99 | 65.203 | Kryptolebias_marmoratus |
ENSG00000167136 | ENDOG | 99 | 67.785 | ENSLBEG00000015579 | endog | 99 | 67.450 | Labrus_bergylta |
ENSG00000167136 | ENDOG | 99 | 67.869 | ENSLACG00000015490 | ENDOG | 97 | 66.667 | Latimeria_chalumnae |
ENSG00000167136 | ENDOG | 98 | 65.333 | ENSLOCG00000004163 | endog | 96 | 65.000 | Lepisosteus_oculatus |
ENSG00000167136 | ENDOG | 55 | 96.341 | ENSLAFG00000028267 | ENDOG | 73 | 96.341 | Loxodonta_africana |
ENSG00000167136 | ENDOG | 100 | 95.987 | ENSMFAG00000044505 | ENDOG | 100 | 95.987 | Macaca_fascicularis |
ENSG00000167136 | ENDOG | 100 | 96.321 | ENSMMUG00000003294 | ENDOG | 100 | 96.321 | Macaca_mulatta |
ENSG00000167136 | ENDOG | 100 | 96.656 | ENSMNEG00000030787 | ENDOG | 100 | 96.656 | Macaca_nemestrina |
ENSG00000167136 | ENDOG | 90 | 68.165 | ENSMAMG00000021431 | endog | 98 | 65.333 | Mastacembelus_armatus |
ENSG00000167136 | ENDOG | 97 | 65.449 | ENSMZEG00005020825 | endog | 98 | 64.430 | Maylandia_zebra |
ENSG00000167136 | ENDOG | 79 | 85.106 | ENSMGAG00000004558 | ENDOG | 99 | 81.226 | Meleagris_gallopavo |
ENSG00000167136 | ENDOG | 100 | 87.919 | ENSMAUG00000015619 | Endog | 100 | 86.195 | Mesocricetus_auratus |
ENSG00000167136 | ENDOG | 80 | 99.163 | ENSMICG00000017648 | ENDOG | 82 | 99.149 | Microcebus_murinus |
ENSG00000167136 | ENDOG | 100 | 88.255 | ENSMOCG00000010842 | Endog | 100 | 86.869 | Microtus_ochrogaster |
ENSG00000167136 | ENDOG | 98 | 64.407 | ENSMMOG00000021056 | endog | 97 | 63.265 | Mola_mola |
ENSG00000167136 | ENDOG | 79 | 88.085 | ENSMODG00000006458 | ENDOG | 100 | 80.068 | Monodelphis_domestica |
ENSG00000167136 | ENDOG | 87 | 65.769 | ENSMALG00000001723 | endog | 99 | 62.457 | Monopterus_albus |
ENSG00000167136 | ENDOG | 100 | 89.262 | MGP_CAROLIEiJ_G0023383 | Endog | 100 | 87.879 | Mus_caroli |
ENSG00000167136 | ENDOG | 100 | 89.262 | ENSMUSG00000015337 | Endog | 100 | 87.879 | Mus_musculus |
ENSG00000167136 | ENDOG | 100 | 89.933 | MGP_PahariEiJ_G0024840 | Endog | 100 | 88.552 | Mus_pahari |
ENSG00000167136 | ENDOG | 100 | 89.262 | MGP_SPRETEiJ_G0024300 | Endog | 100 | 87.879 | Mus_spretus |
ENSG00000167136 | ENDOG | 79 | 96.186 | ENSMPUG00000013024 | ENDOG | 99 | 96.186 | Mustela_putorius_furo |
ENSG00000167136 | ENDOG | 93 | 94.946 | ENSMLUG00000014319 | ENDOG | 100 | 93.603 | Myotis_lucifugus |
ENSG00000167136 | ENDOG | 100 | 83.502 | ENSNGAG00000020601 | Endog | 100 | 83.838 | Nannospalax_galili |
ENSG00000167136 | ENDOG | 95 | 65.763 | ENSNBRG00000023525 | endog | 96 | 64.726 | Neolamprologus_brichardi |
ENSG00000167136 | ENDOG | 67 | 98.500 | ENSNLEG00000017615 | - | 72 | 98.500 | Nomascus_leucogenys |
ENSG00000167136 | ENDOG | 91 | 85.240 | ENSMEUG00000006298 | ENDOG | 100 | 81.481 | Notamacropus_eugenii |
ENSG00000167136 | ENDOG | 100 | 89.967 | ENSODEG00000017274 | ENDOG | 100 | 88.963 | Octodon_degus |
ENSG00000167136 | ENDOG | 80 | 71.074 | ENSONIG00000000792 | endog | 97 | 72.034 | Oreochromis_niloticus |
ENSG00000167136 | ENDOG | 98 | 67.667 | ENSORLG00000016300 | endog | 99 | 66.890 | Oryzias_latipes |
ENSG00000167136 | ENDOG | 97 | 68.027 | ENSORLG00020019290 | endog | 98 | 66.667 | Oryzias_latipes_hni |
ENSG00000167136 | ENDOG | 98 | 67.340 | ENSORLG00015008601 | endog | 99 | 65.986 | Oryzias_latipes_hsok |
ENSG00000167136 | ENDOG | 98 | 66.327 | ENSOMEG00000003638 | endog | 99 | 66.327 | Oryzias_melastigma |
ENSG00000167136 | ENDOG | 100 | 90.635 | ENSOGAG00000024803 | ENDOG | 100 | 90.635 | Otolemur_garnettii |
ENSG00000167136 | ENDOG | 100 | 91.304 | ENSOARG00000009369 | ENDOG | 100 | 91.304 | Ovis_aries |
ENSG00000167136 | ENDOG | 63 | 99.468 | ENSPPAG00000041190 | - | 100 | 99.468 | Pan_paniscus |
ENSG00000167136 | ENDOG | 89 | 94.697 | ENSPPRG00000014165 | ENDOG | 100 | 93.289 | Panthera_pardus |
ENSG00000167136 | ENDOG | 100 | 98.990 | ENSPTRG00000029057 | ENDOG | 100 | 98.990 | Pan_troglodytes |
ENSG00000167136 | ENDOG | 100 | 96.321 | ENSPANG00000025933 | ENDOG | 100 | 96.321 | Papio_anubis |
ENSG00000167136 | ENDOG | 98 | 65.333 | ENSPKIG00000020744 | endog | 96 | 64.667 | Paramormyrops_kingsleyae |
ENSG00000167136 | ENDOG | 53 | 82.278 | ENSPSIG00000018149 | ENDOG | 98 | 82.278 | Pelodiscus_sinensis |
ENSG00000167136 | ENDOG | 98 | 59.060 | ENSPMGG00000015292 | ENDOG | 96 | 60.279 | Periophthalmus_magnuspinnatus |
ENSG00000167136 | ENDOG | 100 | 88.255 | ENSPEMG00000011395 | Endog | 100 | 86.195 | Peromyscus_maniculatus_bairdii |
ENSG00000167136 | ENDOG | 90 | 81.648 | ENSPCIG00000030115 | ENDOG | 99 | 80.068 | Phascolarctos_cinereus |
ENSG00000167136 | ENDOG | 98 | 65.552 | ENSPFOG00000011891 | endog | 98 | 64.765 | Poecilia_formosa |
ENSG00000167136 | ENDOG | 98 | 65.217 | ENSPLAG00000007233 | endog | 98 | 64.430 | Poecilia_latipinna |
ENSG00000167136 | ENDOG | 98 | 65.886 | ENSPMEG00000013321 | endog | 98 | 65.101 | Poecilia_mexicana |
ENSG00000167136 | ENDOG | 98 | 65.886 | ENSPREG00000016271 | endog | 98 | 64.983 | Poecilia_reticulata |
ENSG00000167136 | ENDOG | 100 | 97.306 | ENSPPYG00000019663 | ENDOG | 100 | 97.306 | Pongo_abelii |
ENSG00000167136 | ENDOG | 100 | 89.298 | ENSPCAG00000012182 | ENDOG | 100 | 88.963 | Procavia_capensis |
ENSG00000167136 | ENDOG | 100 | 95.333 | ENSPCOG00000022447 | ENDOG | 100 | 95.333 | Propithecus_coquereli |
ENSG00000167136 | ENDOG | 100 | 87.086 | ENSPVAG00000003453 | ENDOG | 100 | 87.086 | Pteropus_vampyrus |
ENSG00000167136 | ENDOG | 80 | 72.917 | ENSPNYG00000003381 | endog | 82 | 73.932 | Pundamilia_nyererei |
ENSG00000167136 | ENDOG | 99 | 67.000 | ENSPNAG00000024256 | endog | 97 | 67.000 | Pygocentrus_nattereri |
ENSG00000167136 | ENDOG | 100 | 88.591 | ENSRNOG00000016033 | Endog | 100 | 86.869 | Rattus_norvegicus |
ENSG00000167136 | ENDOG | 93 | 90.975 | ENSRBIG00000026558 | ENDOG | 94 | 92.075 | Rhinopithecus_bieti |
ENSG00000167136 | ENDOG | 100 | 83.838 | ENSRROG00000038553 | ENDOG | 100 | 83.838 | Rhinopithecus_roxellana |
ENSG00000167136 | ENDOG | 73 | 42.920 | YJL208C | - | 67 | 43.439 | Saccharomyces_cerevisiae |
ENSG00000167136 | ENDOG | 55 | 97.546 | ENSSBOG00000019144 | ENDOG | 100 | 97.546 | Saimiri_boliviensis_boliviensis |
ENSG00000167136 | ENDOG | 93 | 53.169 | ENSSHAG00000018851 | ENDOG | 100 | 54.181 | Sarcophilus_harrisii |
ENSG00000167136 | ENDOG | 98 | 64.901 | ENSSFOG00015010139 | endog | 96 | 64.570 | Scleropages_formosus |
ENSG00000167136 | ENDOG | 89 | 69.776 | ENSSMAG00000017279 | endog | 94 | 66.894 | Scophthalmus_maximus |
ENSG00000167136 | ENDOG | 77 | 69.565 | ENSSLDG00000007492 | endog | 73 | 64.400 | Seriola_lalandi_dorsalis |
ENSG00000167136 | ENDOG | 99 | 67.219 | ENSSPAG00000005798 | endog | 99 | 65.101 | Stegastes_partitus |
ENSG00000167136 | ENDOG | 100 | 91.639 | ENSSSCG00000005661 | ENDOG | 100 | 91.639 | Sus_scrofa |
ENSG00000167136 | ENDOG | 72 | 82.791 | ENSTGUG00000004197 | ENDOG | 100 | 82.791 | Taeniopygia_guttata |
ENSG00000167136 | ENDOG | 75 | 65.625 | ENSTRUG00000018259 | endog | 62 | 65.625 | Takifugu_rubripes |
ENSG00000167136 | ENDOG | 99 | 61.270 | ENSTNIG00000002481 | endog | 97 | 62.046 | Tetraodon_nigroviridis |
ENSG00000167136 | ENDOG | 79 | 94.894 | ENSTBEG00000007286 | ENDOG | 96 | 94.894 | Tupaia_belangeri |
ENSG00000167136 | ENDOG | 93 | 87.681 | ENSTTRG00000011615 | ENDOG | 99 | 85.424 | Tursiops_truncatus |
ENSG00000167136 | ENDOG | 83 | 95.142 | ENSUAMG00000016280 | ENDOG | 100 | 84.512 | Ursus_americanus |
ENSG00000167136 | ENDOG | 79 | 96.610 | ENSVVUG00000025998 | ENDOG | 82 | 97.021 | Vulpes_vulpes |
ENSG00000167136 | ENDOG | 99 | 66.554 | ENSXETG00000025614 | endog | 98 | 65.986 | Xenopus_tropicalis |
ENSG00000167136 | ENDOG | 59 | 74.286 | ENSXCOG00000012514 | endog | 54 | 74.854 | Xiphophorus_couchianus |
ENSG00000167136 | ENDOG | 60 | 74.011 | ENSXMAG00000027949 | endog | 57 | 75.439 | Xiphophorus_maculatus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000014 | single-stranded DNA endodeoxyribonuclease activity | 21873635. | IBA | Function |
GO:0000737 | DNA catabolic process, endonucleolytic | 21873635. | IBA | Process |
GO:0001701 | in utero embryonic development | - | IEA | Process |
GO:0003676 | nucleic acid binding | - | IEA | Function |
GO:0004519 | endonuclease activity | 21873635. | IBA | Function |
GO:0004521 | endoribonuclease activity | 21873635. | IBA | Function |
GO:0004529 | exodeoxyribonuclease activity | 21873635. | IBA | Function |
GO:0005515 | protein binding | 25036637. | IPI | Function |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005739 | mitochondrion | 21873635. | IBA | Component |
GO:0005743 | mitochondrial inner membrane | 21873635. | IBA | Component |
GO:0005829 | cytosol | - | IEA | Component |
GO:0006309 | apoptotic DNA fragmentation | 21873635. | IBA | Process |
GO:0006310 | DNA recombination | 18309324. | TAS | Process |
GO:0007568 | aging | - | IEA | Process |
GO:0009612 | response to mechanical stimulus | - | IEA | Process |
GO:0032355 | response to estradiol | - | IEA | Process |
GO:0034612 | response to tumor necrosis factor | - | IEA | Process |
GO:0036475 | neuron death in response to oxidative stress | - | IEA | Process |
GO:0043204 | perikaryon | - | IEA | Component |
GO:0046677 | response to antibiotic | - | IEA | Process |
GO:0046872 | metal ion binding | - | IEA | Function |
GO:0071277 | cellular response to calcium ion | - | IEA | Process |
GO:0071333 | cellular response to glucose stimulus | - | IEA | Process |
GO:0071456 | cellular response to hypoxia | - | IEA | Process |
GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | - | IEA | Process |
GO:1901300 | positive regulation of hydrogen peroxide-mediated programmed cell death | - | IEA | Process |
GO:1902512 | positive regulation of apoptotic DNA fragmentation | - | IEA | Process |
Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
KIRC | |||||||
LIHC | |||||||
LUSC | |||||||
LUSC | |||||||
PAAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
LAML | |||
LGG | |||
LIHC | |||
PRAD | |||
THCA | |||
THYM | |||
UCS |
Cancer | P-value | Q-value |
---|---|---|
THYM | ||
STAD | ||
ACC | ||
UCS | ||
SKCM | ||
PRAD | ||
KIRP | ||
PAAD | ||
LAML | ||
UCEC | ||
DLBC | ||
LGG | ||
LUAD | ||
UVM |