EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000167986 (Gene tree)
Gene ID: 1642
Gene Symbol: DDB1
Alias: N
Full Name: damage specific DNA binding protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 43,150 bases
Position: chr11:61,299,447-61,342,596
Accession: 2717
RBP type: canonical RBP
Summary: The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000301764	CPSF_A	PF03178.15	1.7e-85	1	1
ENSP00000445844	CPSF_A	PF03178.15	1.1e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21846828	Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins.	MBio	2011 Aug 16	Bortz E	doi: 10.1128/mBio.00151-11
20566564	Overexpression of UV-DAMAGED DNA BINDING PROTEIN 1 links plant development and phytonutrient accumulation in high pigment-1 tomato.	J Exp Bot	2010 Aug	Azari R	doi: 10.1093/jxb/erq176
23929719	Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease.	Hepatology	2014 Feb	Morikawa K	doi: 10.1002/hep.26671

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000538129	DDB1-210	475	-	-	- (aa)	-	-
ENST00000543162	DDB1-221	575	-	-	- (aa)	-	-
ENST00000543627	DDB1-222	540	-	ENSP00000440660	109 (aa)	-	F5GYG8
ENST00000539739	DDB1-216	1624	-	-	- (aa)	-	-
ENST00000535967	DDB1-207	1404	-	-	- (aa)	-	-
ENST00000451943	DDB1-203	1224	-	-	- (aa)	-	-
ENST00000535174	DDB1-205	896	-	-	- (aa)	-	-
ENST00000539712	DDB1-215	1020	-	-	- (aa)	-	-
ENST00000545930	DDB1-225	1278	-	-	- (aa)	-	-
ENST00000537877	DDB1-209	1375	-	-	- (aa)	-	-
ENST00000301764	DDB1-201	4506	-	ENSP00000301764	1140 (aa)	-	Q16531
ENST00000545894	DDB1-224	2282	-	-	- (aa)	-	-
ENST00000540784	DDB1-218	1119	-	-	- (aa)	-	-
ENST00000539426	DDB1-214	805	-	ENSP00000445554	165 (aa)	-	F5H2L3
ENST00000414411	DDB1-202	1904	-	-	- (aa)	-	-
ENST00000540166	DDB1-217	3906	-	ENSP00000440269	1092 (aa)	-	F5GY55
ENST00000535283	DDB1-206	1220	-	ENSP00000441825	139 (aa)	-	F5GWI0
ENST00000535147	DDB1-204	2789	-	-	- (aa)	-	-
ENST00000541513	DDB1-219	958	-	-	- (aa)	-	-
ENST00000539332	DDB1-213	1767	-	-	- (aa)	-	-
ENST00000537120	DDB1-208	1215	-	-	- (aa)	-	-
ENST00000538470	DDB1-212	858	-	-	- (aa)	-	-
ENST00000542337	DDB1-220	558	-	ENSP00000444105	146 (aa)	-	F5GZY8
ENST00000543658	DDB1-223	571	-	ENSP00000445844	162 (aa)	-	F5H198
ENST00000538280	DDB1-211	227	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000167986's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03420	Nucleotide excision repair	KEGG
hsa04120	Ubiquitin mediated proteolysis	KEGG
hsa05161	Hepatitis B	KEGG
hsa05170	Human immunodeficiency virus 1 infection	KEGG
hsa05203	Viral carcinogenesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000167986's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000167986	DDB1	100	95.890	ENSAPOG00000005036	ddb1	99	91.429	Acanthochromis_polyacanthus
ENSG00000167986	DDB1	100	100.000	ENSAMEG00000016518	DDB1	100	99.912	Ailuropoda_melanoleuca
ENSG00000167986	DDB1	100	95.890	ENSACIG00000020624	ddb1	99	91.735	Amphilophus_citrinellus
ENSG00000167986	DDB1	100	96.575	ENSAOCG00000003066	ddb1	100	91.053	Amphiprion_ocellaris
ENSG00000167986	DDB1	100	96.575	ENSAPEG00000000092	ddb1	100	91.140	Amphiprion_percula
ENSG00000167986	DDB1	100	95.890	ENSATEG00000020571	ddb1	97	91.705	Anabas_testudineus
ENSG00000167986	DDB1	99	96.933	ENSAPLG00000007174	DDB1	99	96.444	Anas_platyrhynchos
ENSG00000167986	DDB1	100	97.576	ENSACAG00000017758	DDB1	100	96.930	Anolis_carolinensis
ENSG00000167986	DDB1	100	100.000	ENSANAG00000021878	DDB1	100	100.000	Aotus_nancymaae
ENSG00000167986	DDB1	100	95.890	ENSACLG00000012401	ddb1	100	91.404	Astatotilapia_calliptera
ENSG00000167986	DDB1	100	100.000	ENSBTAG00000021569	DDB1	93	99.737	Bos_taurus
ENSG00000167986	DDB1	100	41.053	WBGene00010890	ddb-1	100	37.126	Caenorhabditis_elegans
ENSG00000167986	DDB1	100	100.000	ENSCJAG00000019319	DDB1	100	100.000	Callithrix_jacchus
ENSG00000167986	DDB1	100	100.000	ENSCAFG00000016264	DDB1	100	99.912	Canis_familiaris
ENSG00000167986	DDB1	100	100.000	ENSCAFG00020012722	DDB1	99	99.720	Canis_lupus_dingo
ENSG00000167986	DDB1	100	100.000	ENSCHIG00000014969	DDB1	100	99.737	Capra_hircus
ENSG00000167986	DDB1	100	100.000	ENSTSYG00000008027	DDB1	100	99.123	Carlito_syrichta
ENSG00000167986	DDB1	100	98.788	ENSCAPG00000010786	DDB1	100	99.106	Cavia_aperea
ENSG00000167986	DDB1	100	99.315	ENSCPOG00000009956	DDB1	100	99.123	Cavia_porcellus
ENSG00000167986	DDB1	100	100.000	ENSCCAG00000035883	DDB1	100	100.000	Cebus_capucinus
ENSG00000167986	DDB1	100	100.000	ENSCATG00000044495	DDB1	100	97.483	Cercocebus_atys
ENSG00000167986	DDB1	100	100.000	ENSCLAG00000004126	DDB1	100	99.211	Chinchilla_lanigera
ENSG00000167986	DDB1	100	100.000	ENSCSAG00000006392	DDB1	100	100.000	Chlorocebus_sabaeus
ENSG00000167986	DDB1	100	97.849	ENSCHOG00000011377	DDB1	90	92.803	Choloepus_hoffmanni
ENSG00000167986	DDB1	100	98.788	ENSCPBG00000017728	DDB1	100	97.632	Chrysemys_picta_bellii
ENSG00000167986	DDB1	100	67.606	ENSCING00000007437	-	100	61.892	Ciona_intestinalis
ENSG00000167986	DDB1	94	60.276	ENSCSAVG00000004783	-	100	60.276	Ciona_savignyi
ENSG00000167986	DDB1	100	100.000	ENSCANG00000019948	DDB1	100	100.000	Colobus_angolensis_palliatus
ENSG00000167986	DDB1	100	100.000	ENSCGRG00001016599	Ddb1	100	99.825	Cricetulus_griseus_chok1gshd
ENSG00000167986	DDB1	100	100.000	ENSCGRG00000013427	Ddb1	100	99.825	Cricetulus_griseus_crigri
ENSG00000167986	DDB1	100	94.521	ENSCSEG00000012499	ddb1	99	89.575	Cynoglossus_semilaevis
ENSG00000167986	DDB1	100	96.575	ENSCVAG00000019531	ddb1	99	91.333	Cyprinodon_variegatus
ENSG00000167986	DDB1	100	96.575	ENSDARG00000074431	ddb1	100	88.384	Danio_rerio
ENSG00000167986	DDB1	100	100.000	ENSDNOG00000014884	DDB1	97	99.348	Dasypus_novemcinctus
ENSG00000167986	DDB1	100	100.000	ENSDORG00000000127	Ddb1	100	100.000	Dipodomys_ordii
ENSG00000167986	DDB1	100	61.048	FBgn0260962	pic	100	60.839	Drosophila_melanogaster
ENSG00000167986	DDB1	100	100.000	ENSETEG00000001053	-	71	100.000	Echinops_telfairi
ENSG00000167986	DDB1	100	90.411	ENSEBUG00000014593	ddb1	97	84.927	Eptatretus_burgeri
ENSG00000167986	DDB1	100	100.000	ENSEASG00005008184	DDB1	100	99.737	Equus_asinus_asinus
ENSG00000167986	DDB1	100	100.000	ENSECAG00000012136	DDB1	100	99.649	Equus_caballus
ENSG00000167986	DDB1	89	97.475	ENSEEUG00000003194	DDB1	85	97.475	Erinaceus_europaeus
ENSG00000167986	DDB1	100	96.575	ENSELUG00000023868	ddb1	100	91.140	Esox_lucius
ENSG00000167986	DDB1	100	100.000	ENSFCAG00000029716	DDB1	100	99.912	Felis_catus
ENSG00000167986	DDB1	100	96.970	ENSFALG00000011981	DDB1	100	96.850	Ficedula_albicollis
ENSG00000167986	DDB1	100	100.000	ENSFDAG00000005128	DDB1	100	99.123	Fukomys_damarensis
ENSG00000167986	DDB1	100	96.575	ENSFHEG00000022133	ddb1	98	90.588	Fundulus_heteroclitus
ENSG00000167986	DDB1	82	94.649	ENSGMOG00000019386	ddb1	94	94.649	Gadus_morhua
ENSG00000167986	DDB1	100	97.260	ENSGALG00000042333	DDB1	100	97.018	Gallus_gallus
ENSG00000167986	DDB1	100	96.575	ENSGAFG00000013142	ddb1	99	91.146	Gambusia_affinis
ENSG00000167986	DDB1	100	96.575	ENSGACG00000017182	ddb1	100	90.559	Gasterosteus_aculeatus
ENSG00000167986	DDB1	100	98.788	ENSGAGG00000014124	DDB1	100	97.694	Gopherus_agassizii
ENSG00000167986	DDB1	100	100.000	ENSGGOG00000004052	DDB1	100	100.000	Gorilla_gorilla
ENSG00000167986	DDB1	100	95.890	ENSHBUG00000008873	ddb1	100	91.404	Haplochromis_burtoni
ENSG00000167986	DDB1	100	100.000	ENSHGLG00000018430	DDB1	100	99.035	Heterocephalus_glaber_female
ENSG00000167986	DDB1	100	100.000	ENSHGLG00100014475	DDB1	100	97.982	Heterocephalus_glaber_male
ENSG00000167986	DDB1	100	95.890	ENSHCOG00000018670	ddb1	98	91.053	Hippocampus_comes
ENSG00000167986	DDB1	100	95.890	ENSIPUG00000005612	DDB1	100	90.439	Ictalurus_punctatus
ENSG00000167986	DDB1	100	100.000	ENSSTOG00000007552	DDB1	100	99.825	Ictidomys_tridecemlineatus
ENSG00000167986	DDB1	100	100.000	ENSJJAG00000017769	Ddb1	100	99.649	Jaculus_jaculus
ENSG00000167986	DDB1	100	96.575	ENSKMAG00000002315	ddb1	99	91.333	Kryptolebias_marmoratus
ENSG00000167986	DDB1	99	94.512	ENSLBEG00000017065	ddb1	99	91.399	Labrus_bergylta
ENSG00000167986	DDB1	100	96.364	ENSLACG00000017611	DDB1	100	93.520	Latimeria_chalumnae
ENSG00000167986	DDB1	98	95.327	ENSLOCG00000000012	ddb1	100	83.333	Lepisosteus_oculatus
ENSG00000167986	DDB1	100	100.000	ENSLAFG00000011513	DDB1	100	99.649	Loxodonta_africana
ENSG00000167986	DDB1	100	100.000	ENSMFAG00000042035	DDB1	100	100.000	Macaca_fascicularis
ENSG00000167986	DDB1	100	100.000	ENSMMUG00000002691	DDB1	100	100.000	Macaca_mulatta
ENSG00000167986	DDB1	100	100.000	ENSMNEG00000031559	DDB1	100	100.000	Macaca_nemestrina
ENSG00000167986	DDB1	100	100.000	ENSMLEG00000044136	DDB1	100	100.000	Mandrillus_leucophaeus
ENSG00000167986	DDB1	100	96.575	ENSMAMG00000014372	ddb1	100	91.404	Mastacembelus_armatus
ENSG00000167986	DDB1	100	95.890	ENSMZEG00005013835	ddb1	100	91.316	Maylandia_zebra
ENSG00000167986	DDB1	94	96.369	ENSMGAG00000004990	DDB1	100	96.369	Meleagris_gallopavo
ENSG00000167986	DDB1	100	100.000	ENSMAUG00000012926	Ddb1	100	99.825	Mesocricetus_auratus
ENSG00000167986	DDB1	100	100.000	ENSMICG00000013703	DDB1	100	99.825	Microcebus_murinus
ENSG00000167986	DDB1	100	99.561	ENSMOCG00000020499	Ddb1	100	99.561	Microtus_ochrogaster
ENSG00000167986	DDB1	100	96.575	ENSMMOG00000001758	ddb1	99	91.735	Mola_mola
ENSG00000167986	DDB1	100	100.000	ENSMODG00000020353	DDB1	100	89.187	Monodelphis_domestica
ENSG00000167986	DDB1	100	96.575	ENSMALG00000014071	ddb1	100	91.404	Monopterus_albus
ENSG00000167986	DDB1	100	100.000	MGP_CAROLIEiJ_G0022695	Ddb1	100	99.737	Mus_caroli
ENSG00000167986	DDB1	100	100.000	ENSMUSG00000024740	Ddb1	100	99.649	Mus_musculus
ENSG00000167986	DDB1	100	100.000	MGP_PahariEiJ_G0014189	Ddb1	100	99.737	Mus_pahari
ENSG00000167986	DDB1	100	100.000	MGP_SPRETEiJ_G0023609	Ddb1	100	99.737	Mus_spretus
ENSG00000167986	DDB1	100	100.000	ENSMPUG00000014200	DDB1	100	96.579	Mustela_putorius_furo
ENSG00000167986	DDB1	100	100.000	ENSMLUG00000013232	DDB1	100	99.298	Myotis_lucifugus
ENSG00000167986	DDB1	100	100.000	ENSNGAG00000009384	Ddb1	100	99.386	Nannospalax_galili
ENSG00000167986	DDB1	100	95.890	ENSNBRG00000019581	ddb1	100	91.491	Neolamprologus_brichardi
ENSG00000167986	DDB1	100	100.000	ENSNLEG00000002022	DDB1	100	96.875	Nomascus_leucogenys
ENSG00000167986	DDB1	91	99.648	ENSMEUG00000001099	DDB1	93	99.648	Notamacropus_eugenii
ENSG00000167986	DDB1	90	90.980	ENSOPRG00000008254	DDB1	90	90.980	Ochotona_princeps
ENSG00000167986	DDB1	100	100.000	ENSODEG00000002419	DDB1	100	99.035	Octodon_degus
ENSG00000167986	DDB1	100	95.890	ENSONIG00000005804	ddb1	100	91.404	Oreochromis_niloticus
ENSG00000167986	DDB1	91	98.062	ENSOANG00000004897	DDB1	100	98.062	Ornithorhynchus_anatinus
ENSG00000167986	DDB1	100	100.000	ENSOCUG00000001667	DDB1	100	99.825	Oryctolagus_cuniculus
ENSG00000167986	DDB1	100	94.521	ENSORLG00000001399	ddb1	98	91.066	Oryzias_latipes
ENSG00000167986	DDB1	100	94.521	ENSORLG00020001277	ddb1	97	89.734	Oryzias_latipes_hni
ENSG00000167986	DDB1	100	94.521	ENSORLG00015002080	ddb1	99	90.884	Oryzias_latipes_hsok
ENSG00000167986	DDB1	100	94.521	ENSOMEG00000006181	ddb1	99	89.699	Oryzias_melastigma
ENSG00000167986	DDB1	100	100.000	ENSOGAG00000016103	DDB1	100	99.649	Otolemur_garnettii
ENSG00000167986	DDB1	100	100.000	ENSOARG00000011716	DDB1	98	99.733	Ovis_aries
ENSG00000167986	DDB1	100	100.000	ENSPPAG00000035343	DDB1	100	100.000	Pan_paniscus
ENSG00000167986	DDB1	100	100.000	ENSPPRG00000013300	DDB1	100	99.912	Panthera_pardus
ENSG00000167986	DDB1	100	100.000	ENSPTIG00000006909	DDB1	98	99.911	Panthera_tigris_altaica
ENSG00000167986	DDB1	100	100.000	ENSPTRG00000003737	DDB1	100	100.000	Pan_troglodytes
ENSG00000167986	DDB1	100	100.000	ENSPANG00000000242	DDB1	100	100.000	Papio_anubis
ENSG00000167986	DDB1	100	97.260	ENSPKIG00000019213	ddb1	94	91.240	Paramormyrops_kingsleyae
ENSG00000167986	DDB1	100	97.576	ENSPSIG00000013275	DDB1	100	96.975	Pelodiscus_sinensis
ENSG00000167986	DDB1	100	95.890	ENSPMGG00000021179	ddb1	99	91.429	Periophthalmus_magnuspinnatus
ENSG00000167986	DDB1	100	100.000	ENSPEMG00000012241	Ddb1	100	99.825	Peromyscus_maniculatus_bairdii
ENSG00000167986	DDB1	100	89.091	ENSPMAG00000008479	ddb1	100	86.739	Petromyzon_marinus
ENSG00000167986	DDB1	100	100.000	ENSPCIG00000002643	DDB1	100	98.947	Phascolarctos_cinereus
ENSG00000167986	DDB1	100	96.575	ENSPFOG00000002768	ddb1	100	90.798	Poecilia_formosa
ENSG00000167986	DDB1	100	96.575	ENSPLAG00000017227	ddb1	100	90.614	Poecilia_latipinna
ENSG00000167986	DDB1	100	96.575	ENSPMEG00000011398	ddb1	100	90.614	Poecilia_mexicana
ENSG00000167986	DDB1	100	96.575	ENSPREG00000004440	ddb1	98	91.256	Poecilia_reticulata
ENSG00000167986	DDB1	100	100.000	ENSPPYG00000003193	DDB1	100	95.026	Pongo_abelii
ENSG00000167986	DDB1	100	94.000	ENSPCAG00000011040	DDB1	85	99.403	Procavia_capensis
ENSG00000167986	DDB1	100	100.000	ENSPCOG00000015176	DDB1	100	98.249	Propithecus_coquereli
ENSG00000167986	DDB1	100	100.000	ENSPVAG00000003847	DDB1	100	99.737	Pteropus_vampyrus
ENSG00000167986	DDB1	57	88.172	ENSPNYG00000010482	ddb1	100	90.036	Pundamilia_nyererei
ENSG00000167986	DDB1	100	96.575	ENSPNAG00000006635	ddb1	97	91.240	Pygocentrus_nattereri
ENSG00000167986	DDB1	100	100.000	ENSRNOG00000020715	Ddb1	100	99.737	Rattus_norvegicus
ENSG00000167986	DDB1	100	100.000	ENSRBIG00000033611	DDB1	100	100.000	Rhinopithecus_bieti
ENSG00000167986	DDB1	100	100.000	ENSRROG00000041407	DDB1	100	100.000	Rhinopithecus_roxellana
ENSG00000167986	DDB1	100	100.000	ENSSBOG00000019775	DDB1	100	99.912	Saimiri_boliviensis_boliviensis
ENSG00000167986	DDB1	92	99.338	ENSSHAG00000011600	DDB1	100	96.916	Sarcophilus_harrisii
ENSG00000167986	DDB1	100	96.575	ENSSFOG00015011151	ddb1	97	91.357	Scleropages_formosus
ENSG00000167986	DDB1	100	96.575	ENSSMAG00000009495	ddb1	100	90.965	Scophthalmus_maximus
ENSG00000167986	DDB1	100	96.575	ENSSDUG00000004642	ddb1	100	91.316	Seriola_dumerili
ENSG00000167986	DDB1	100	96.575	ENSSLDG00000015804	ddb1	100	91.316	Seriola_lalandi_dorsalis
ENSG00000167986	DDB1	81	100.000	ENSSARG00000003290	-	72	100.000	Sorex_araneus
ENSG00000167986	DDB1	100	100.000	ENSSPUG00000019338	DDB1	100	97.807	Sphenodon_punctatus
ENSG00000167986	DDB1	100	96.575	ENSSPAG00000009888	ddb1	99	91.612	Stegastes_partitus
ENSG00000167986	DDB1	100	100.000	ENSSSCG00000013094	DDB1	100	98.860	Sus_scrofa
ENSG00000167986	DDB1	100	97.945	ENSTGUG00000006414	DDB1	100	97.018	Taeniopygia_guttata
ENSG00000167986	DDB1	100	95.413	ENSTRUG00000016682	ddb1	98	90.214	Takifugu_rubripes
ENSG00000167986	DDB1	88	84.930	ENSTNIG00000009565	ddb1	99	84.930	Tetraodon_nigroviridis
ENSG00000167986	DDB1	91	100.000	ENSTTRG00000011055	DDB1	94	94.778	Tursiops_truncatus
ENSG00000167986	DDB1	100	100.000	ENSUAMG00000017793	DDB1	93	99.720	Ursus_americanus
ENSG00000167986	DDB1	100	100.000	ENSUMAG00000011788	DDB1	98	99.720	Ursus_maritimus
ENSG00000167986	DDB1	100	100.000	ENSVPAG00000007963	DDB1	92	100.000	Vicugna_pacos
ENSG00000167986	DDB1	100	100.000	ENSVVUG00000004987	DDB1	100	99.825	Vulpes_vulpes
ENSG00000167986	DDB1	100	96.364	ENSXETG00000008820	ddb1	100	93.182	Xenopus_tropicalis
ENSG00000167986	DDB1	100	96.575	ENSXCOG00000013956	ddb1	99	91.224	Xiphophorus_couchianus
ENSG00000167986	DDB1	100	96.575	ENSXMAG00000000022	ddb1	99	91.146	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000715	nucleotide-excision repair, DNA damage recognition	-	TAS	Process
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	-	TAS	Process
GO:0000784	nuclear chromosome, telomeric region	19135898.	HDA	Component
GO:0003677	DNA binding	8798680.	TAS	Function
GO:0003684	damaged DNA binding	21873635.	IBA	Function
GO:0003684	damaged DNA binding	22334663.	IDA	Function
GO:0005515	protein binding	9418871.12732143.14739464.16227264.16473935.16949367.16964240.17041588.17314515.17360488.17932509.19109893.19264781.19651607.19966799.20223979.20855601.21113133.21988832.22039351.22157821.22810585.22822215.23238014.23314863.24292623.24412650.26131937.26496610.26909574.28437394.	IPI	Function
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	18593899.20223979.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	18593899.20223979.23137809.	IDA	Component
GO:0006281	DNA repair	8798680.	TAS	Process
GO:0006283	transcription-coupled nucleotide-excision repair	-	TAS	Process
GO:0006289	nucleotide-excision repair	8407967.	TAS	Process
GO:0006293	nucleotide-excision repair, preincision complex stabilization	-	TAS	Process
GO:0006294	nucleotide-excision repair, preincision complex assembly	-	TAS	Process
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	-	TAS	Process
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	-	TAS	Process
GO:0006511	ubiquitin-dependent protein catabolic process	11673459.	IDA	Process
GO:0006511	ubiquitin-dependent protein catabolic process	26431207.	IMP	Process
GO:0006974	cellular response to DNA damage stimulus	16949367.	IMP	Process
GO:0010498	proteasomal protein catabolic process	25970626.	IMP	Process
GO:0016032	viral process	-	IEA	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0016567	protein ubiquitination	26431207.	IDA	Process
GO:0016567	protein ubiquitination	28437394.	IMP	Process
GO:0030674	protein binding, bridging	14739464.	IPI	Function
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	12732143.14739464.18794347.20129063.20223979.	IDA	Component
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	18794347.21628527.22334663.	IDA	Component
GO:0032991	protein-containing complex	28437394.	IMP	Component
GO:0033683	nucleotide-excision repair, DNA incision	-	TAS	Process
GO:0035518	histone H2A monoubiquitination	22334663.	IDA	Process
GO:0042752	regulation of circadian rhythm	-	IEA	Process
GO:0042769	DNA damage response, detection of DNA damage	-	TAS	Process
GO:0043066	negative regulation of apoptotic process	-	IEA	Process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	21873635.	IBA	Process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	14739464.20223979.	IMP	Process
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0044877	protein-containing complex binding	11564863.	IPI	Function
GO:0045070	positive regulation of viral genome replication	23137809.	IMP	Process
GO:0045722	positive regulation of gluconeogenesis	-	ISS	Process
GO:0045732	positive regulation of protein catabolic process	16949367.	IMP	Process
GO:0046726	positive regulation by virus of viral protein levels in host cell	23137809.	IMP	Process
GO:0051702	interaction with symbiont	23137809.	IDA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0070911	global genome nucleotide-excision repair	-	TAS	Process
GO:0070914	UV-damage excision repair	22334663.	IDA	Process
GO:0071987	WD40-repeat domain binding	16949367.	IPI	Function
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	18381890.	IDA	Component
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	16949367.	IMP	Component
GO:0097602	cullin family protein binding	14739464.	IPI	Function
GO:1901990	regulation of mitotic cell cycle phase transition	17088560.	IMP	Process
GO:1902188	positive regulation of viral release from host cell	23137809.	IMP	Process