EuRBPDB

Description

Ensembl ID: ENSG00000168101 (Gene tree)
Gene ID: 84309
Gene Symbol: NUDT16L1
Alias: SDOS
Full Name: nudix hydrolase 16 like 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,302 bases
Position: chr16:4,693,558-4,695,859
Accession: 28154
RBP type: non-canonical RBP
Summary: (Nudix Hydrolase 16 Like 1) is a Protein Coding gene. Among its related pathways are Proteoglycans in cancer and Syndecan-4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is NUDT16.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18820299	Evolutionary conservation supports ancient origin for Nudt16, a nuclear-localized, RNA-binding, RNA-decapping enzyme.	Nucleic Acids Res	2008 Oct	Taylor MJ	doi: 10.1093/nar/gkn605
30260431	Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation.	Nucleic Acids Res	2018 Dec 14	Avolio R	doi: 10.1093/nar/gky873.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000586536	NUDT16L1-204	1406	-	ENSP00000468346	192 (aa)	-	W4VSQ8
ENST00000590460	NUDT16L1-205	709	-	ENSP00000464821	198 (aa)	-	K7EIN2
ENST00000304301	NUDT16L1-201	1349	-	ENSP00000306670	211 (aa)	-	Q9BRJ7
ENST00000586252	NUDT16L1-203	922	-	ENSP00000466854	171 (aa)	-	K7ENA3
ENST00000405142	NUDT16L1-202	2040	XM_005255633	ENSP00000458144	247 (aa)	XP_005255690	Q9BRJ7

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa05205	Proteoglycans in cancer	KEGG

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000168101	NUDT16L1	100	95.735	ENSMUSG00000022516	Nudt16l1	100	95.735	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	25416956.28241136.	IPI	Function
GO:0005634	nucleus	28241136.	IDA	Component
GO:0030515	snoRNA binding	18820299.21070968.	IDA	Function
GO:0042803	protein homodimerization activity	18820299.	IDA	Function
GO:0050072	m7G(5')pppN diphosphatase activity	18820299.21070968.	IDA	Function
GO:0050072	m7G(5')pppN diphosphatase activity	-	ISS	Function
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	28241136.	IDA	Process