EuRBPDB

Description

Ensembl ID: ENSG00000168259 (Gene tree)
Gene ID: 7266
Gene Symbol: DNAJC7
Alias: TPR2|TTC2
Full Name: DnaJ heat shock protein family (Hsp40) member C7
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 47,372 bases
Position: chr17:41,974,005-42,021,376
Accession: 12392
RBP type: non-canonical RBP
Summary: This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21933837	Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila.	Hum Mol Genet	2011 Dec 15	Shieh SY	doi: 10.1093/hmg/ddr420

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000426588	DNAJC7-202	1774	XM_011525168	ENSP00000394327	438 (aa)	XP_011523470	Q99615
ENST00000588641	DNAJC7-210	782	-	ENSP00000468805	258 (aa)	-	K7ESP1
ENST00000589576	DNAJC7-213	586	-	ENSP00000468102	128 (aa)	-	K7ER44
ENST00000590774	DNAJC7-219	544	-	ENSP00000465340	113 (aa)	-	K7EJV7
ENST00000586335	DNAJC7-207	579	-	ENSP00000464993	89 (aa)	-	K7EJ24
ENST00000589586	DNAJC7-214	620	-	ENSP00000466748	104 (aa)	-	K7EN19
ENST00000589810	DNAJC7-216	1058	-	ENSP00000467477	253 (aa)	-	K7EPP7
ENST00000589547	DNAJC7-212	541	-	-	- (aa)	-	-
ENST00000590886	DNAJC7-221	543	-	ENSP00000465399	75 (aa)	-	K7EK03
ENST00000591787	DNAJC7-223	566	-	ENSP00000465140	74 (aa)	-	K7EJE9
ENST00000587380	DNAJC7-208	1956	-	-	- (aa)	-	-
ENST00000587727	DNAJC7-209	449	-	ENSP00000467702	55 (aa)	-	K7EQ73
ENST00000588814	DNAJC7-211	1719	-	ENSP00000466114	137 (aa)	-	K7ELJ8
ENST00000316603	DNAJC7-201	1468	XM_011525167	ENSP00000313311	438 (aa)	XP_011523469	Q99615
ENST00000585693	DNAJC7-204	562	-	-	- (aa)	-	-
ENST00000591153	DNAJC7-222	431	-	-	- (aa)	-	-
ENST00000586240	DNAJC7-206	2564	-	-	- (aa)	-	-
ENST00000457167	DNAJC7-203	2022	-	ENSP00000406463	494 (aa)	-	Q99615
ENST00000585866	DNAJC7-205	686	-	ENSP00000466877	39 (aa)	-	K7ENB7
ENST00000590847	DNAJC7-220	441	-	-	- (aa)	-	-
ENST00000590197	DNAJC7-217	1762	-	-	- (aa)	-	-
ENST00000589773	DNAJC7-215	678	-	ENSP00000465228	102 (aa)	-	K7EJL5
ENST00000590348	DNAJC7-218	832	-	ENSP00000464756	261 (aa)	-	K7EIH8

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	22190034.25036637.26496610.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	12853476.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0006457	protein folding	8836031.	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0031072	heat shock protein binding	12853476.	IPI	Function
GO:0051085	chaperone cofactor-dependent protein refolding	12853476.18620420.	IDA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:1900034	regulation of cellular response to heat	-	TAS	Process