EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000168348 (Gene tree)
Gene ID: 84684
Gene Symbol: INSM2
Alias: IA-6|Mlt1
Full Name: INSM transcriptional repressor 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 3,013 bases
Position: chr14:35,534,042-35,537,054
Accession: 17539
RBP type: canonical RBP
Summary: INSM2 (INSM Transcriptional Repressor 2) is a Protein Coding gene. Diseases associated with INSM2 include Insulinoma. An important paralog of this gene is INSM1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000306523	zf-C2H2	PF00096.26	2.2e-13	1	2
ENSP00000306523	zf-C2H2	PF00096.26	2.2e-13	2	2
ENSP00000306523	zf-met	PF12874.7	0.00054	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000307169	INSM2-201	3013	-	ENSP00000306523	566 (aa)	-	Q96T92

Gene Model

Click here to download ENSG00000168348's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000168348's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000168348	INSM2	62	49.180	ENSAPOG00000008900	INSM2	72	49.180	Acanthochromis_polyacanthus
ENSG00000168348	INSM2	100	85.009	ENSAMEG00000019215	INSM2	100	85.009	Ailuropoda_melanoleuca
ENSG00000168348	INSM2	84	49.102	ENSAOCG00000012374	INSM2	64	47.486	Amphiprion_ocellaris
ENSG00000168348	INSM2	61	50.407	ENSATEG00000010035	INSM2	82	51.075	Anabas_testudineus
ENSG00000168348	INSM2	100	83.774	ENSBTAG00000027013	INSM2	100	84.656	Bos_taurus
ENSG00000168348	INSM2	100	93.684	ENSCJAG00000006816	INSM2	100	93.333	Callithrix_jacchus
ENSG00000168348	INSM2	100	84.303	ENSCAFG00000013428	INSM2	100	83.951	Canis_familiaris
ENSG00000168348	INSM2	100	76.190	ENSCAFG00020023381	INSM2	100	75.838	Canis_lupus_dingo
ENSG00000168348	INSM2	100	76.678	ENSCHIG00000019716	INSM2	100	76.678	Capra_hircus
ENSG00000168348	INSM2	97	63.206	ENSCPOG00000013937	INSM2	99	63.685	Cavia_porcellus
ENSG00000168348	INSM2	100	95.423	ENSCATG00000021263	INSM2	100	95.599	Cercocebus_atys
ENSG00000168348	INSM2	100	95.423	ENSCSAG00000019401	INSM2	100	95.599	Chlorocebus_sabaeus
ENSG00000168348	INSM2	100	66.078	ENSCGRG00001024873	Insm2	100	67.196	Cricetulus_griseus_chok1gshd
ENSG00000168348	INSM2	99	38.288	ENSCVAG00000002938	INSM2	100	38.462	Cyprinodon_variegatus
ENSG00000168348	INSM2	100	84.276	ENSDNOG00000007824	INSM2	100	84.276	Dasypus_novemcinctus
ENSG00000168348	INSM2	100	81.095	ENSETEG00000019088	INSM2	100	80.742	Echinops_telfairi
ENSG00000168348	INSM2	86	89.035	ENSEASG00005002073	INSM2	100	77.208	Equus_asinus_asinus
ENSG00000168348	INSM2	100	87.102	ENSECAG00000034097	INSM2	94	87.102	Equus_caballus
ENSG00000168348	INSM2	66	69.496	ENSEEUG00000015087	-	100	71.277	Erinaceus_europaeus
ENSG00000168348	INSM2	100	85.538	ENSFCAG00000025118	INSM2	100	85.891	Felis_catus
ENSG00000168348	INSM2	100	97.719	ENSGGOG00000041074	INSM2	100	97.719	Gorilla_gorilla
ENSG00000168348	INSM2	99	37.055	ENSHBUG00000016523	INSM2	53	46.797	Haplochromis_burtoni
ENSG00000168348	INSM2	100	73.852	ENSHGLG00000002192	INSM2	100	75.265	Heterocephalus_glaber_female
ENSG00000168348	INSM2	99	40.102	ENSHCOG00000012981	INSM2	65	47.103	Hippocampus_comes
ENSG00000168348	INSM2	68	42.931	ENSIPUG00000012507	INSM2	70	42.424	Ictalurus_punctatus
ENSG00000168348	INSM2	100	76.502	ENSSTOG00000026540	INSM2	100	75.618	Ictidomys_tridecemlineatus
ENSG00000168348	INSM2	100	68.750	ENSJJAG00000003814	Insm2	100	68.924	Jaculus_jaculus
ENSG00000168348	INSM2	99	40.131	ENSKMAG00000008248	INSM2	66	49.618	Kryptolebias_marmoratus
ENSG00000168348	INSM2	97	38.416	ENSLACG00000012262	-	60	60.976	Latimeria_chalumnae
ENSG00000168348	INSM2	100	44.618	ENSLACG00000017606	INSM2	100	44.444	Latimeria_chalumnae
ENSG00000168348	INSM2	100	80.035	ENSLAFG00000008242	INSM2	100	80.035	Loxodonta_africana
ENSG00000168348	INSM2	100	95.599	ENSMFAG00000009696	INSM2	100	95.775	Macaca_fascicularis
ENSG00000168348	INSM2	100	95.599	ENSMMUG00000016483	INSM2	100	95.775	Macaca_mulatta
ENSG00000168348	INSM2	77	95.276	ENSMLEG00000038100	INSM2	100	95.538	Mandrillus_leucophaeus
ENSG00000168348	INSM2	61	47.922	ENSMAMG00000013231	INSM2	51	47.368	Mastacembelus_armatus
ENSG00000168348	INSM2	100	66.078	ENSMAUG00000003017	Insm2	100	66.608	Mesocricetus_auratus
ENSG00000168348	INSM2	100	65.724	ENSMOCG00000008493	Insm2	100	66.078	Microtus_ochrogaster
ENSG00000168348	INSM2	54	62.411	ENSMMOG00000004655	INSM2	53	43.454	Mola_mola
ENSG00000168348	INSM2	100	84.480	ENSMPUG00000019565	INSM2	100	84.480	Mustela_putorius_furo
ENSG00000168348	INSM2	100	64.903	ENSMLUG00000026985	INSM2	100	64.386	Myotis_lucifugus
ENSG00000168348	INSM2	80	77.966	ENSNGAG00000000506	Insm2	100	77.966	Nannospalax_galili
ENSG00000168348	INSM2	86	96.429	ENSNLEG00000003723	INSM2	100	96.429	Nomascus_leucogenys
ENSG00000168348	INSM2	88	82.273	ENSODEG00000006944	INSM2	100	82.857	Octodon_degus
ENSG00000168348	INSM2	100	80.565	ENSOCUG00000006804	INSM2	100	80.919	Oryctolagus_cuniculus
ENSG00000168348	INSM2	99	40.909	ENSORLG00020016414	INSM2	100	40.909	Oryzias_latipes_hni
ENSG00000168348	INSM2	80	38.947	ENSORLG00015012891	INSM2	90	40.323	Oryzias_latipes_hsok
ENSG00000168348	INSM2	67	47.870	ENSOMEG00000011237	INSM2	90	47.870	Oryzias_melastigma
ENSG00000168348	INSM2	100	89.046	ENSOGAG00000024855	INSM2	100	89.046	Otolemur_garnettii
ENSG00000168348	INSM2	76	84.615	ENSPPAG00000013978	-	87	84.615	Pan_paniscus
ENSG00000168348	INSM2	100	85.538	ENSPPRG00000018323	INSM2	100	85.891	Panthera_pardus
ENSG00000168348	INSM2	100	98.944	ENSPTRG00000006267	INSM2	100	98.944	Pan_troglodytes
ENSG00000168348	INSM2	100	95.246	ENSPANG00000021247	INSM2	100	95.423	Papio_anubis
ENSG00000168348	INSM2	82	57.534	ENSPKIG00000009894	INSM2	90	58.503	Paramormyrops_kingsleyae
ENSG00000168348	INSM2	61	49.030	ENSPMGG00000008732	INSM2	71	48.199	Periophthalmus_magnuspinnatus
ENSG00000168348	INSM2	84	70.103	ENSPCIG00000017418	INSM2	99	69.592	Phascolarctos_cinereus
ENSG00000168348	INSM2	99	35.679	ENSPLAG00000022202	INSM2	52	58.394	Poecilia_latipinna
ENSG00000168348	INSM2	67	43.814	ENSPMEG00000011388	INSM2	60	43.814	Poecilia_mexicana
ENSG00000168348	INSM2	90	97.287	ENSPPYG00000005745	INSM2	100	97.287	Pongo_abelii
ENSG00000168348	INSM2	100	83.392	ENSPCAG00000004250	INSM2	100	83.392	Procavia_capensis
ENSG00000168348	INSM2	100	84.629	ENSPVAG00000003511	INSM2	100	84.629	Pteropus_vampyrus
ENSG00000168348	INSM2	99	38.188	ENSPNYG00000022741	INSM2	53	48.747	Pundamilia_nyererei
ENSG00000168348	INSM2	100	63.604	ENSRNOG00000007754	Insm2	100	64.851	Rattus_norvegicus
ENSG00000168348	INSM2	100	94.366	ENSRBIG00000037192	INSM2	100	94.542	Rhinopithecus_bieti
ENSG00000168348	INSM2	100	83.746	ENSSBOG00000020749	INSM2	100	85.159	Saimiri_boliviensis_boliviensis
ENSG00000168348	INSM2	100	62.544	ENSSHAG00000008600	INSM2	100	61.592	Sarcophilus_harrisii
ENSG00000168348	INSM2	100	39.831	ENSSFOG00015012029	INSM2	100	39.425	Scleropages_formosus
ENSG00000168348	INSM2	82	52.027	ENSSPAG00000000980	INSM2	53	47.500	Stegastes_partitus
ENSG00000168348	INSM2	100	76.450	ENSSSCG00000001949	INSM2	100	76.450	Sus_scrofa
ENSG00000168348	INSM2	63	48.942	ENSTRUG00000021982	-	59	50.398	Takifugu_rubripes
ENSG00000168348	INSM2	61	40.341	ENSTNIG00000000248	INSM2	100	40.625	Tetraodon_nigroviridis
ENSG00000168348	INSM2	98	86.511	ENSTTRG00000007971	INSM2	100	86.511	Tursiops_truncatus
ENSG00000168348	INSM2	100	80.071	ENSUAMG00000006503	INSM2	100	80.071	Ursus_americanus
ENSG00000168348	INSM2	80	89.404	ENSVPAG00000010440	INSM2	100	89.404	Vicugna_pacos
ENSG00000168348	INSM2	100	77.072	ENSVVUG00000020010	INSM2	100	77.072	Vulpes_vulpes
ENSG00000168348	INSM2	84	45.946	ENSXMAG00000013820	INSM2	55	55.921	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function