EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000168517 (Gene tree)
Gene ID: 124790
Gene Symbol: HEXIM2
Alias: FLJ32384
Full Name: HEXIM P-TEFb complex subunit 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,015 bases
Position: chr17:45,160,026-45,170,040
Accession: 28591
RBP type: canonical RBP
Summary: This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000302276	HEXIM	PF15313.6	1.7e-45	1	1
ENSP00000465727	HEXIM	PF15313.6	1.7e-45	1	1
ENSP00000467517	HEXIM	PF15313.6	1.7e-45	1	1
ENSP00000468251	HEXIM	PF15313.6	5.1e-29	1	1
ENSP00000465086	HEXIM	PF15313.6	3.3e-18	1	1
ENSP00000466200	HEXIM	PF15313.6	6.2e-13	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15965233	Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.	J Biol Chem	2005 Aug 5	Li Q	-
17395637	HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells.	Nucleic Acids Res	2007	Li Q	-
19246988	7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor.	RNA Biol	2009 Apr-Jun	Diribarne G	-
17709395	The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes.	Mol Cell Biol	2007 Oct	Barrandon C	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000585340	HEXIM2-202	803	XM_006721687	ENSP00000468251	203 (aa)	XP_006721750	K7ERG7
ENST00000592695	HEXIM2-207	1246	XM_017024167	ENSP00000467517	286 (aa)	XP_016879656	Q96MH2
ENST00000586681	HEXIM2-203	783	-	ENSP00000465086	144 (aa)	-	K7EJA3
ENST00000591070	HEXIM2-205	473	-	ENSP00000464807	79 (aa)	-	K7EIM4
ENST00000307275	HEXIM2-201	1528	XM_011524306	ENSP00000302276	286 (aa)	XP_011522608	Q96MH2
ENST00000593138	HEXIM2-208	581	-	ENSP00000468773	122 (aa)	-	K7ESM2
ENST00000589230	HEXIM2-204	796	-	ENSP00000466200	139 (aa)	-	K7ELS4
ENST00000591576	HEXIM2-206	1176	XM_011524307	ENSP00000465727	286 (aa)	XP_011522609	Q96MH2

Gene Model

Click here to download ENSG00000168517's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000168517	Platelet Function Tests	1.7277700E-005	-
ENSG00000168517	Platelet Function Tests	1.4751800E-005	-
ENSG00000168517	Platelet Function Tests	1.9382200E-005	-
ENSG00000168517	Cholesterol, LDL	2.4430000E-005	-
ENSG00000168517	Blood Pressure	4.7414877E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000168517's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000168517	HEXIM2	65	52.239	ENSG00000186834	HEXIM1	55	54.229

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000168517	HEXIM2	60	47.668	ENSAPOG00000005717	hexim1	58	49.289	Acanthochromis_polyacanthus
ENSG00000168517	HEXIM2	99	84.615	ENSAMEG00000018404	HEXIM2	92	84.561	Ailuropoda_melanoleuca
ENSG00000168517	HEXIM2	65	52.239	ENSAMEG00000019935	HEXIM1	55	53.731	Ailuropoda_melanoleuca
ENSG00000168517	HEXIM2	66	49.296	ENSACIG00000008752	hexim1	59	49.296	Amphilophus_citrinellus
ENSG00000168517	HEXIM2	60	47.150	ENSAOCG00000010682	hexim1	58	48.815	Amphiprion_ocellaris
ENSG00000168517	HEXIM2	60	47.150	ENSAPEG00000002466	hexim1	58	48.815	Amphiprion_percula
ENSG00000168517	HEXIM2	53	50.000	ENSATEG00000023429	hexim1	59	46.296	Anabas_testudineus
ENSG00000168517	HEXIM2	58	52.874	ENSAPLG00000007934	HEXIM1	96	53.488	Anas_platyrhynchos
ENSG00000168517	HEXIM2	70	52.804	ENSACAG00000016321	HEXIM1	69	53.774	Anolis_carolinensis
ENSG00000168517	HEXIM2	65	52.239	ENSANAG00000012950	HEXIM1	55	54.229	Aotus_nancymaae
ENSG00000168517	HEXIM2	100	93.056	ENSANAG00000034525	HEXIM2	100	91.958	Aotus_nancymaae
ENSG00000168517	HEXIM2	66	47.418	ENSACLG00000000640	hexim1	59	47.887	Astatotilapia_calliptera
ENSG00000168517	HEXIM2	99	81.818	ENSBTAG00000024974	HEXIM2	97	81.404	Bos_taurus
ENSG00000168517	HEXIM2	65	50.990	ENSBTAG00000006056	HEXIM1	62	52.475	Bos_taurus
ENSG00000168517	HEXIM2	100	92.657	ENSCJAG00000047668	-	100	92.657	Callithrix_jacchus
ENSG00000168517	HEXIM2	65	52.736	ENSCJAG00000041689	HEXIM1	55	54.726	Callithrix_jacchus
ENSG00000168517	HEXIM2	100	92.657	ENSCJAG00000048269	-	100	92.657	Callithrix_jacchus
ENSG00000168517	HEXIM2	92	92.803	ENSCJAG00000046816	-	100	92.803	Callithrix_jacchus
ENSG00000168517	HEXIM2	100	93.671	ENSCJAG00000047902	-	100	90.909	Callithrix_jacchus
ENSG00000168517	HEXIM2	99	85.315	ENSCAFG00000013831	HEXIM2	99	83.509	Canis_familiaris
ENSG00000168517	HEXIM2	65	52.239	ENSCAFG00000024148	HEXIM1	53	53.731	Canis_familiaris
ENSG00000168517	HEXIM2	97	83.755	ENSCAFG00020009518	HEXIM2	97	83.755	Canis_lupus_dingo
ENSG00000168517	HEXIM2	65	52.239	ENSCAFG00020009524	HEXIM1	55	53.731	Canis_lupus_dingo
ENSG00000168517	HEXIM2	65	50.990	ENSCHIG00000003683	HEXIM1	62	52.475	Capra_hircus
ENSG00000168517	HEXIM2	99	80.420	ENSCHIG00000006446	HEXIM2	97	79.649	Capra_hircus
ENSG00000168517	HEXIM2	99	76.224	ENSTSYG00000031348	HEXIM2	98	76.449	Carlito_syrichta
ENSG00000168517	HEXIM2	64	52.261	ENSTSYG00000031366	HEXIM1	79	49.780	Carlito_syrichta
ENSG00000168517	HEXIM2	63	56.701	ENSCPOG00000007132	-	87	59.686	Cavia_porcellus
ENSG00000168517	HEXIM2	100	93.750	ENSCCAG00000036207	HEXIM2	100	93.706	Cebus_capucinus
ENSG00000168517	HEXIM2	65	52.239	ENSCCAG00000019243	HEXIM1	55	54.229	Cebus_capucinus
ENSG00000168517	HEXIM2	100	96.853	ENSCATG00000034723	HEXIM2	100	96.853	Cercocebus_atys
ENSG00000168517	HEXIM2	65	52.239	ENSCATG00000014762	HEXIM1	55	54.229	Cercocebus_atys
ENSG00000168517	HEXIM2	65	52.239	ENSCSAG00000019019	HEXIM1	55	54.229	Chlorocebus_sabaeus
ENSG00000168517	HEXIM2	100	97.552	ENSCSAG00000003672	HEXIM2	100	97.552	Chlorocebus_sabaeus
ENSG00000168517	HEXIM2	65	51.724	ENSCPBG00000008858	HEXIM1	82	53.695	Chrysemys_picta_bellii
ENSG00000168517	HEXIM2	65	52.239	ENSCANG00000019421	HEXIM1	55	54.229	Colobus_angolensis_palliatus
ENSG00000168517	HEXIM2	100	96.154	ENSCANG00000031165	HEXIM2	100	96.154	Colobus_angolensis_palliatus
ENSG00000168517	HEXIM2	99	77.622	ENSCGRG00001014831	Hexim2	91	77.622	Cricetulus_griseus_chok1gshd
ENSG00000168517	HEXIM2	65	52.736	ENSCGRG00001002270	Hexim1	56	54.229	Cricetulus_griseus_chok1gshd
ENSG00000168517	HEXIM2	65	52.736	ENSCGRG00000019550	Hexim1	56	54.229	Cricetulus_griseus_crigri
ENSG00000168517	HEXIM2	99	77.622	ENSCGRG00000008734	Hexim2	91	77.622	Cricetulus_griseus_crigri
ENSG00000168517	HEXIM2	66	47.926	ENSCVAG00000012890	hexim1	60	48.848	Cyprinodon_variegatus
ENSG00000168517	HEXIM2	57	46.597	ENSDARG00000036482	hexim1	64	51.442	Danio_rerio
ENSG00000168517	HEXIM2	64	51.232	ENSDNOG00000042085	HEXIM1	56	54.040	Dasypus_novemcinctus
ENSG00000168517	HEXIM2	99	84.615	ENSDNOG00000008936	HEXIM2	97	83.509	Dasypus_novemcinctus
ENSG00000168517	HEXIM2	65	52.239	ENSDORG00000014730	Hexim1	56	53.731	Dipodomys_ordii
ENSG00000168517	HEXIM2	99	76.655	ENSDORG00000014731	Hexim2	100	76.655	Dipodomys_ordii
ENSG00000168517	HEXIM2	92	79.924	ENSETEG00000018494	HEXIM2	100	79.924	Echinops_telfairi
ENSG00000168517	HEXIM2	69	41.748	ENSEBUG00000011914	hexim1	69	41.748	Eptatretus_burgeri
ENSG00000168517	HEXIM2	65	52.239	ENSEASG00005010424	HEXIM1	55	53.731	Equus_asinus_asinus
ENSG00000168517	HEXIM2	99	79.298	ENSEASG00005010425	HEXIM2	99	79.298	Equus_asinus_asinus
ENSG00000168517	HEXIM2	65	52.239	ENSECAG00000000859	HEXIM1	55	53.731	Equus_caballus
ENSG00000168517	HEXIM2	97	80.144	ENSECAG00000018388	HEXIM2	100	80.144	Equus_caballus
ENSG00000168517	HEXIM2	65	51.980	ENSEEUG00000011611	HEXIM1	92	54.000	Erinaceus_europaeus
ENSG00000168517	HEXIM2	99	77.465	ENSEEUG00000005259	HEXIM2	99	77.465	Erinaceus_europaeus
ENSG00000168517	HEXIM2	56	46.354	ENSELUG00000016611	hexim1	81	50.242	Esox_lucius
ENSG00000168517	HEXIM2	65	52.239	ENSFCAG00000005475	HEXIM1	55	53.731	Felis_catus
ENSG00000168517	HEXIM2	99	85.315	ENSFCAG00000026386	HEXIM2	99	83.158	Felis_catus
ENSG00000168517	HEXIM2	59	51.913	ENSFALG00000009364	HEXIM1	81	51.982	Ficedula_albicollis
ENSG00000168517	HEXIM2	53	51.412	ENSFHEG00000011351	hexim1	68	48.611	Fundulus_heteroclitus
ENSG00000168517	HEXIM2	56	52.874	ENSGMOG00000017844	hexim1	79	53.769	Gadus_morhua
ENSG00000168517	HEXIM2	80	54.237	ENSGALG00000041926	HEXIM1	88	48.462	Gallus_gallus
ENSG00000168517	HEXIM2	66	46.296	ENSGAFG00000002769	hexim1	59	48.148	Gambusia_affinis
ENSG00000168517	HEXIM2	54	52.410	ENSGACG00000009408	hexim1	81	48.039	Gasterosteus_aculeatus
ENSG00000168517	HEXIM2	69	50.926	ENSGAGG00000015869	HEXIM1	89	52.778	Gopherus_agassizii
ENSG00000168517	HEXIM2	65	52.239	ENSGGOG00000014370	HEXIM1	55	54.229	Gorilla_gorilla
ENSG00000168517	HEXIM2	100	100.000	ENSGGOG00000007926	HEXIM2	100	100.000	Gorilla_gorilla
ENSG00000168517	HEXIM2	66	47.418	ENSHBUG00000000196	hexim1	59	47.887	Haplochromis_burtoni
ENSG00000168517	HEXIM2	64	56.345	ENSHGLG00000008489	HEXIM1	85	58.974	Heterocephalus_glaber_female
ENSG00000168517	HEXIM2	69	46.522	ENSIPUG00000004319	hexim1	66	48.684	Ictalurus_punctatus
ENSG00000168517	HEXIM2	99	81.119	ENSSTOG00000009448	HEXIM2	100	81.119	Ictidomys_tridecemlineatus
ENSG00000168517	HEXIM2	65	51.741	ENSSTOG00000019464	HEXIM1	55	53.234	Ictidomys_tridecemlineatus
ENSG00000168517	HEXIM2	65	52.000	ENSJJAG00000006094	Hexim1	56	55.000	Jaculus_jaculus
ENSG00000168517	HEXIM2	99	75.789	ENSJJAG00000018759	Hexim2	91	75.789	Jaculus_jaculus
ENSG00000168517	HEXIM2	66	48.113	ENSKMAG00000011029	hexim1	62	50.000	Kryptolebias_marmoratus
ENSG00000168517	HEXIM2	60	52.486	ENSLACG00000003325	hexim1	99	54.271	Latimeria_chalumnae
ENSG00000168517	HEXIM2	56	47.368	ENSLACG00000003660	-	95	44.712	Latimeria_chalumnae
ENSG00000168517	HEXIM2	60	43.750	ENSLOCG00000017511	hexim1	68	48.035	Lepisosteus_oculatus
ENSG00000168517	HEXIM2	65	52.736	ENSLAFG00000022721	HEXIM1	55	54.229	Loxodonta_africana
ENSG00000168517	HEXIM2	99	79.787	ENSLAFG00000014694	HEXIM2	100	79.787	Loxodonta_africana
ENSG00000168517	HEXIM2	65	52.239	ENSMFAG00000030480	HEXIM1	55	54.229	Macaca_fascicularis
ENSG00000168517	HEXIM2	100	97.552	ENSMFAG00000032794	HEXIM2	100	97.552	Macaca_fascicularis
ENSG00000168517	HEXIM2	100	97.552	ENSMMUG00000000713	HEXIM2	100	97.552	Macaca_mulatta
ENSG00000168517	HEXIM2	65	52.239	ENSMMUG00000042910	HEXIM1	55	54.229	Macaca_mulatta
ENSG00000168517	HEXIM2	100	97.552	ENSMNEG00000032116	HEXIM2	100	97.552	Macaca_nemestrina
ENSG00000168517	HEXIM2	65	52.239	ENSMNEG00000000901	HEXIM1	55	54.229	Macaca_nemestrina
ENSG00000168517	HEXIM2	100	97.203	ENSMLEG00000038451	HEXIM2	100	97.203	Mandrillus_leucophaeus
ENSG00000168517	HEXIM2	65	52.239	ENSMLEG00000024845	HEXIM1	55	54.229	Mandrillus_leucophaeus
ENSG00000168517	HEXIM2	53	50.000	ENSMAMG00000022061	hexim1	59	47.685	Mastacembelus_armatus
ENSG00000168517	HEXIM2	66	47.418	ENSMZEG00005022967	hexim1	59	47.887	Maylandia_zebra
ENSG00000168517	HEXIM2	65	52.736	ENSMAUG00000018509	Hexim1	80	54.229	Mesocricetus_auratus
ENSG00000168517	HEXIM2	99	76.923	ENSMAUG00000021720	Hexim2	91	76.923	Mesocricetus_auratus
ENSG00000168517	HEXIM2	99	87.719	ENSMICG00000041666	HEXIM2	100	87.719	Microcebus_murinus
ENSG00000168517	HEXIM2	99	76.573	ENSMOCG00000007400	Hexim2	91	76.573	Microtus_ochrogaster
ENSG00000168517	HEXIM2	65	53.234	ENSMOCG00000004118	Hexim1	80	54.229	Microtus_ochrogaster
ENSG00000168517	HEXIM2	56	50.625	ENSMMOG00000020884	hexim1	68	44.915	Mola_mola
ENSG00000168517	HEXIM2	92	55.556	ENSMODG00000024024	HEXIM2	100	60.148	Monodelphis_domestica
ENSG00000168517	HEXIM2	65	52.239	ENSMODG00000011185	HEXIM1	55	53.731	Monodelphis_domestica
ENSG00000168517	HEXIM2	66	46.698	ENSMALG00000009105	hexim1	58	46.698	Monopterus_albus
ENSG00000168517	HEXIM2	65	52.736	MGP_CAROLIEiJ_G0017273	Hexim1	56	54.229	Mus_caroli
ENSG00000168517	HEXIM2	99	77.660	MGP_CAROLIEiJ_G0017274	Hexim2	100	75.862	Mus_caroli
ENSG00000168517	HEXIM2	99	78.014	ENSMUSG00000043372	Hexim2	100	75.862	Mus_musculus
ENSG00000168517	HEXIM2	65	52.736	ENSMUSG00000048878	Hexim1	56	54.229	Mus_musculus
ENSG00000168517	HEXIM2	72	48.673	MGP_PahariEiJ_G0018403	Hexim1	62	50.222	Mus_pahari
ENSG00000168517	HEXIM2	99	76.950	MGP_PahariEiJ_G0018404	Hexim2	100	74.713	Mus_pahari
ENSG00000168517	HEXIM2	99	77.660	MGP_SPRETEiJ_G0018117	Hexim2	100	75.862	Mus_spretus
ENSG00000168517	HEXIM2	65	52.736	MGP_SPRETEiJ_G0018116	Hexim1	56	54.229	Mus_spretus
ENSG00000168517	HEXIM2	99	81.818	ENSMPUG00000008646	HEXIM2	91	83.099	Mustela_putorius_furo
ENSG00000168517	HEXIM2	65	52.239	ENSMPUG00000019044	HEXIM1	55	53.731	Mustela_putorius_furo
ENSG00000168517	HEXIM2	65	54.500	ENSMLUG00000005554	HEXIM1	55	54.545	Myotis_lucifugus
ENSG00000168517	HEXIM2	97	78.986	ENSMLUG00000005556	HEXIM2	94	78.986	Myotis_lucifugus
ENSG00000168517	HEXIM2	99	77.193	ENSNGAG00000008154	Hexim2	90	77.193	Nannospalax_galili
ENSG00000168517	HEXIM2	52	56.442	ENSNGAG00000004671	Hexim1	56	53.731	Nannospalax_galili
ENSG00000168517	HEXIM2	66	47.418	ENSNBRG00000020486	hexim1	59	47.887	Neolamprologus_brichardi
ENSG00000168517	HEXIM2	100	99.306	ENSNLEG00000031095	HEXIM2	100	98.252	Nomascus_leucogenys
ENSG00000168517	HEXIM2	65	52.736	ENSNLEG00000029192	HEXIM1	55	54.726	Nomascus_leucogenys
ENSG00000168517	HEXIM2	95	75.182	ENSOPRG00000012395	HEXIM2	97	75.182	Ochotona_princeps
ENSG00000168517	HEXIM2	64	60.309	ENSODEG00000018098	HEXIM1	89	59.794	Octodon_degus
ENSG00000168517	HEXIM2	64	49.038	ENSONIG00000020929	hexim1	59	48.826	Oreochromis_niloticus
ENSG00000168517	HEXIM2	67	51.220	ENSOCUG00000006748	HEXIM1	61	52.683	Oryctolagus_cuniculus
ENSG00000168517	HEXIM2	99	80.212	ENSOCUG00000006750	HEXIM2	90	80.212	Oryctolagus_cuniculus
ENSG00000168517	HEXIM2	66	47.222	ENSORLG00000023814	hexim1	59	47.907	Oryzias_latipes
ENSG00000168517	HEXIM2	66	47.222	ENSORLG00020010120	hexim1	59	48.611	Oryzias_latipes_hni
ENSG00000168517	HEXIM2	64	48.571	ENSORLG00015002827	hexim1	66	50.000	Oryzias_latipes_hsok
ENSG00000168517	HEXIM2	64	48.804	ENSOMEG00000021356	hexim1	59	50.239	Oryzias_melastigma
ENSG00000168517	HEXIM2	65	52.239	ENSOGAG00000009304	HEXIM1	55	53.731	Otolemur_garnettii
ENSG00000168517	HEXIM2	99	87.368	ENSOGAG00000009303	HEXIM2	100	87.368	Otolemur_garnettii
ENSG00000168517	HEXIM2	99	81.119	ENSOARG00000009856	HEXIM2	95	79.859	Ovis_aries
ENSG00000168517	HEXIM2	65	52.239	ENSPPAG00000013758	HEXIM1	55	54.229	Pan_paniscus
ENSG00000168517	HEXIM2	100	100.000	ENSPPAG00000009894	HEXIM2	100	100.000	Pan_paniscus
ENSG00000168517	HEXIM2	65	52.239	ENSPPRG00000021693	HEXIM1	55	53.731	Panthera_pardus
ENSG00000168517	HEXIM2	99	86.014	ENSPPRG00000001652	HEXIM2	99	83.509	Panthera_pardus
ENSG00000168517	HEXIM2	99	86.014	ENSPTIG00000019231	HEXIM2	99	83.509	Panthera_tigris_altaica
ENSG00000168517	HEXIM2	65	52.239	ENSPTIG00000001145	HEXIM1	55	53.731	Panthera_tigris_altaica
ENSG00000168517	HEXIM2	65	52.239	ENSPTRG00000049378	HEXIM1	55	54.229	Pan_troglodytes
ENSG00000168517	HEXIM2	100	100.000	ENSPTRG00000009299	HEXIM2	100	100.000	Pan_troglodytes
ENSG00000168517	HEXIM2	65	52.239	ENSPANG00000017530	HEXIM1	55	54.229	Papio_anubis
ENSG00000168517	HEXIM2	100	97.203	ENSPANG00000021251	HEXIM2	100	97.203	Papio_anubis
ENSG00000168517	HEXIM2	61	46.305	ENSPKIG00000002959	hexim1	61	48.214	Paramormyrops_kingsleyae
ENSG00000168517	HEXIM2	59	45.771	ENSPKIG00000021934	hexim1	59	48.198	Paramormyrops_kingsleyae
ENSG00000168517	HEXIM2	62	53.886	ENSPSIG00000009902	HEXIM1	95	51.131	Pelodiscus_sinensis
ENSG00000168517	HEXIM2	52	54.023	ENSPMGG00000001490	hexim1	67	48.325	Periophthalmus_magnuspinnatus
ENSG00000168517	HEXIM2	65	54.726	ENSPEMG00000001808	Hexim1	59	54.229	Peromyscus_maniculatus_bairdii
ENSG00000168517	HEXIM2	99	75.887	ENSPEMG00000001356	Hexim2	90	75.887	Peromyscus_maniculatus_bairdii
ENSG00000168517	HEXIM2	62	47.000	ENSPMAG00000003486	hexim1	91	51.485	Petromyzon_marinus
ENSG00000168517	HEXIM2	65	52.239	ENSPCIG00000015058	HEXIM1	55	53.731	Phascolarctos_cinereus
ENSG00000168517	HEXIM2	93	57.143	ENSPCIG00000015059	HEXIM2	87	62.132	Phascolarctos_cinereus
ENSG00000168517	HEXIM2	53	50.847	ENSPFOG00000020082	hexim1	86	48.611	Poecilia_formosa
ENSG00000168517	HEXIM2	53	50.282	ENSPLAG00000002325	hexim1	59	48.148	Poecilia_latipinna
ENSG00000168517	HEXIM2	53	50.847	ENSPMEG00000019068	hexim1	59	48.611	Poecilia_mexicana
ENSG00000168517	HEXIM2	53	50.282	ENSPREG00000008937	hexim1	59	47.222	Poecilia_reticulata
ENSG00000168517	HEXIM2	100	98.252	ENSPPYG00000008310	HEXIM2	100	98.252	Pongo_abelii
ENSG00000168517	HEXIM2	52	54.601	ENSPCAG00000015764	HEXIM1	56	52.736	Procavia_capensis
ENSG00000168517	HEXIM2	99	60.331	ENSPCAG00000015843	HEXIM2	95	59.420	Procavia_capensis
ENSG00000168517	HEXIM2	99	88.772	ENSPCOG00000008648	HEXIM2	99	88.772	Propithecus_coquereli
ENSG00000168517	HEXIM2	88	84.190	ENSPVAG00000013115	HEXIM2	100	82.576	Pteropus_vampyrus
ENSG00000168517	HEXIM2	66	47.887	ENSPNYG00000012838	hexim1	59	48.357	Pundamilia_nyererei
ENSG00000168517	HEXIM2	79	44.402	ENSPNAG00000005803	hexim1	79	45.946	Pygocentrus_nattereri
ENSG00000168517	HEXIM2	99	77.660	ENSRNOG00000021287	Hexim2	90	77.660	Rattus_norvegicus
ENSG00000168517	HEXIM2	65	52.736	ENSRNOG00000003203	Hexim1	56	54.229	Rattus_norvegicus
ENSG00000168517	HEXIM2	100	98.252	ENSRBIG00000041800	HEXIM2	100	98.252	Rhinopithecus_bieti
ENSG00000168517	HEXIM2	65	52.239	ENSRBIG00000027049	-	55	54.229	Rhinopithecus_bieti
ENSG00000168517	HEXIM2	100	98.252	ENSRROG00000042011	HEXIM2	100	98.252	Rhinopithecus_roxellana
ENSG00000168517	HEXIM2	65	52.239	ENSRROG00000013037	HEXIM1	55	54.229	Rhinopithecus_roxellana
ENSG00000168517	HEXIM2	100	94.056	ENSSBOG00000021727	HEXIM2	100	94.056	Saimiri_boliviensis_boliviensis
ENSG00000168517	HEXIM2	65	52.239	ENSSBOG00000016824	HEXIM1	55	54.229	Saimiri_boliviensis_boliviensis
ENSG00000168517	HEXIM2	96	61.151	ENSSHAG00000011037	HEXIM2	99	62.500	Sarcophilus_harrisii
ENSG00000168517	HEXIM2	65	52.239	ENSSHAG00000010963	HEXIM1	56	53.731	Sarcophilus_harrisii
ENSG00000168517	HEXIM2	53	51.705	ENSSDUG00000022563	hexim1	59	47.222	Seriola_dumerili
ENSG00000168517	HEXIM2	55	42.169	ENSSDUG00000006682	-	60	42.246	Seriola_dumerili
ENSG00000168517	HEXIM2	53	50.568	ENSSLDG00000000246	hexim1	60	47.222	Seriola_lalandi_dorsalis
ENSG00000168517	HEXIM2	85	77.049	ENSSARG00000007906	-	100	57.955	Sorex_araneus
ENSG00000168517	HEXIM2	67	55.446	ENSSPUG00000010560	-	59	55.446	Sphenodon_punctatus
ENSG00000168517	HEXIM2	60	47.668	ENSSPAG00000003586	hexim1	58	49.289	Stegastes_partitus
ENSG00000168517	HEXIM2	83	86.555	ENSSSCG00000017335	HEXIM2	100	86.555	Sus_scrofa
ENSG00000168517	HEXIM2	62	45.411	ENSTRUG00000019644	hexim1	58	47.032	Takifugu_rubripes
ENSG00000168517	HEXIM2	62	47.644	ENSTNIG00000000815	hexim1	74	48.768	Tetraodon_nigroviridis
ENSG00000168517	HEXIM2	99	83.916	ENSTTRG00000006285	HEXIM2	99	84.912	Tursiops_truncatus
ENSG00000168517	HEXIM2	99	81.119	ENSUAMG00000024042	HEXIM2	99	82.456	Ursus_americanus
ENSG00000168517	HEXIM2	65	52.239	ENSUAMG00000024043	HEXIM1	80	53.731	Ursus_americanus
ENSG00000168517	HEXIM2	99	77.622	ENSUMAG00000014481	HEXIM2	97	74.386	Ursus_maritimus
ENSG00000168517	HEXIM2	65	52.239	ENSUMAG00000014477	HEXIM1	80	53.731	Ursus_maritimus
ENSG00000168517	HEXIM2	99	86.713	ENSVVUG00000018357	HEXIM2	97	85.563	Vulpes_vulpes
ENSG00000168517	HEXIM2	65	52.239	ENSVVUG00000018324	HEXIM1	55	53.731	Vulpes_vulpes
ENSG00000168517	HEXIM2	67	50.463	ENSXETG00000027237	hexim1	74	50.463	Xenopus_tropicalis
ENSG00000168517	HEXIM2	66	47.685	ENSXCOG00000017406	hexim1	59	48.611	Xiphophorus_couchianus
ENSG00000168517	HEXIM2	66	47.685	ENSXMAG00000008423	hexim1	59	48.611	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	15713662.	IDA	Process
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	21873635.	IBA	Function
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	15713662.	IDA	Function
GO:0005515	protein binding	15713661.15713662.19883659.21044950.21516116.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0016607	nuclear speck	-	IDA	Component
GO:0017069	snRNA binding	15713662.	IDA	Function
GO:0042802	identical protein binding	21516116.25416956.	IPI	Function
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	21873635.	IBA	Process
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	15713662.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	15713662.	IDA	Process
GO:0097322	7SK snRNA binding	21873635.	IBA	Function
GO:0097322	7SK snRNA binding	19883659.	IDA	Function