EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169045 (Gene tree)
Gene ID: 3187
Gene Symbol: HNRNPH1
Alias: hnRNPH|HNRPH1
Full Name: heterogeneous nuclear ribonucleoprotein H1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 20,607 bases
Position: chr5:179,614,178-179,634,784
Accession: 5041
RBP type: canonical RBP
Summary: This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000429481	zf-RNPHF	PF08080.12	3.9e-23	1	1
ENSP00000429270	zf-RNPHF	PF08080.12	6.2e-23	1	1
ENSP00000428620	zf-RNPHF	PF08080.12	8.7e-23	1	1
ENSP00000426275	zf-RNPHF	PF08080.12	1.7e-22	1	1
ENSP00000349168	zf-RNPHF	PF08080.12	2.7e-22	1	1
ENSP00000377082	zf-RNPHF	PF08080.12	2.7e-22	1	1
ENSP00000397797	zf-RNPHF	PF08080.12	2.7e-22	1	1
ENSP00000327539	zf-RNPHF	PF08080.12	3.1e-22	1	1
ENSP00000427408	zf-RNPHF	PF08080.12	5.7e-15	1	1
ENSP00000426275	RRM_1	PF00076.22	3.5e-32	1	3
ENSP00000426275	RRM_1	PF00076.22	3.5e-32	2	3
ENSP00000426275	RRM_1	PF00076.22	3.5e-32	3	3
ENSP00000349168	RRM_1	PF00076.22	4.3e-32	1	3
ENSP00000349168	RRM_1	PF00076.22	4.3e-32	2	3
ENSP00000349168	RRM_1	PF00076.22	4.3e-32	3	3
ENSP00000377082	RRM_1	PF00076.22	4.3e-32	1	3
ENSP00000377082	RRM_1	PF00076.22	4.3e-32	2	3
ENSP00000377082	RRM_1	PF00076.22	4.3e-32	3	3
ENSP00000397797	RRM_1	PF00076.22	4.3e-32	1	3
ENSP00000397797	RRM_1	PF00076.22	4.3e-32	2	3
ENSP00000397797	RRM_1	PF00076.22	4.3e-32	3	3
ENSP00000327539	RRM_1	PF00076.22	5.4e-32	1	3
ENSP00000327539	RRM_1	PF00076.22	5.4e-32	2	3
ENSP00000327539	RRM_1	PF00076.22	5.4e-32	3	3
ENSP00000424087	RRM_1	PF00076.22	1.1e-21	1	2
ENSP00000424087	RRM_1	PF00076.22	1.1e-21	2	2
ENSP00000427388	RRM_1	PF00076.22	1.3e-19	1	2
ENSP00000427388	RRM_1	PF00076.22	1.3e-19	2	2
ENSP00000426518	RRM_1	PF00076.22	2.1e-17	1	2
ENSP00000426518	RRM_1	PF00076.22	2.1e-17	2	2
ENSP00000428620	RRM_1	PF00076.22	9.7e-17	1	2
ENSP00000428620	RRM_1	PF00076.22	9.7e-17	2	2
ENSP00000430970	RRM_1	PF00076.22	9.1e-16	1	1
ENSP00000427986	RRM_1	PF00076.22	1.8e-15	1	2
ENSP00000427986	RRM_1	PF00076.22	1.8e-15	2	2
ENSP00000430156	RRM_1	PF00076.22	1.6e-12	1	1
ENSP00000423140	RRM_1	PF00076.22	1.1e-09	1	1
ENSP00000427408	RRM_1	PF00076.22	1.4e-09	1	1
ENSP00000420850	RRM_1	PF00076.22	1.4e-09	1	1
ENSP00000425732	RRM_1	PF00076.22	1.5e-09	1	1
ENSP00000429270	RRM_1	PF00076.22	5.7e-09	1	1
ENSP00000429481	RRM_1	PF00076.22	5.8e-09	1	1
ENSP00000421695	RRM_1	PF00076.22	9.6e-08	1	1
ENSP00000425343	RRM_1	PF00076.22	7.5e-07	1	1
ENSP00000429661	RRM_1	PF00076.22	1.9e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24366528	Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia.	Acta Neuropathol	2014 Mar	Stepto A	doi: 10.1007/s00401-013-1235-1
21739230	Post-transcriptional regulation of mu-opioid receptor: role of the RNA-binding proteins heterogeneous nuclear ribonucleoprotein H1 and F.	Cell Mol Life Sci	2012 Feb	Song KY	doi: 10.1007/s00018-011-0761-z
26776507	Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.	Cell Rep	2016 Jan 26	Grohar PJ	doi: 10.1016/j.celrep.2015.12.063
26192745	Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS.	Nat Neurosci	2015 Aug	Prudencio M	doi: 10.1038/nn.4065
27565210	The long and the short of TRF2 in neurogenesis.	Cell Cycle	2016 Nov 16	Grammatikakis I	-
29362363	HNRNPH1 is required for rhabdomyosarcoma cell growth and survival.	Oncogenesis	2018 Jan 24	Li Y	doi: 10.1038/s41389-017-0024-4.
31227213	Two distinct nuclear stress bodies containing different sets of RNA-binding proteins are formed with HSATIII architectural noncoding RNAs upon thermal stress exposure.	Biochem Biophys Res Commun	2019 Aug 20	Aly MK	doi: 10.1016/j.bbrc.2019.06.061
20457534	The phenylalanine hydroxylase c.30C>G synonymous variation (p.G10G) creates a common exonic splicing silencer.	Mol Genet Metab	2010 Aug	Dobrowolski SF	doi: 10.1016/j.ymgme.2010.04.002
31242972	An antisense lncRNA functions in alternative splicing of Bmdsx in the silkworm, Bombyx mori.	Biochem Biophys Res Commun	2019 Aug 27	Xu X	doi: 10.1016/j.bbrc.2019.06.107

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000513972	HNRNPH1-222	761	-	-	- (aa)	-	-
ENST00000521116	HNRNPH1-238	806	-	ENSP00000429661	115 (aa)	-	E7EQJ0
ENST00000521173	HNRNPH1-239	831	-	ENSP00000428620	277 (aa)	-	H0YB39
ENST00000522256	HNRNPH1-242	492	-	ENSP00000429179	28 (aa)	-	E5RJ94
ENST00000518548	HNRNPH1-229	527	-	-	- (aa)	-	-
ENST00000519707	HNRNPH1-234	582	-	-	- (aa)	-	-
ENST00000523449	HNRNPH1-246	793	-	ENSP00000429673	117 (aa)	-	H0YBK1
ENST00000519033	HNRNPH1-231	832	XM_017009421	ENSP00000429481	185 (aa)	XP_016864912	H0YBG7
ENST00000505811	HNRNPH1-213	1155	-	ENSP00000424087	212 (aa)	-	D6RBM0
ENST00000515714	HNRNPH1-228	690	-	ENSP00000425343	84 (aa)	-	D6RDL0
ENST00000521720	HNRNPH1-240	539	-	-	- (aa)	-	-
ENST00000393432	HNRNPH1-203	2279	XM_017009417	ENSP00000377082	449 (aa)	XP_016864906	P31943
ENST00000514731	HNRNPH1-224	1371	-	-	- (aa)	-	-
ENST00000502632	HNRNPH1-205	1509	-	-	- (aa)	-	-
ENST00000442819	HNRNPH1-204	2248	-	ENSP00000397797	449 (aa)	-	P31943
ENST00000503664	HNRNPH1-208	569	-	ENSP00000426726	49 (aa)	-	D6RF17
ENST00000522958	HNRNPH1-243	580	-	-	- (aa)	-	-
ENST00000519958	HNRNPH1-236	885	-	ENSP00000427845	131 (aa)	-	H0YAQ2
ENST00000504348	HNRNPH1-209	594	-	ENSP00000427388	168 (aa)	-	D6RIU0
ENST00000504549	HNRNPH1-210	980	-	-	- (aa)	-	-
ENST00000513230	HNRNPH1-221	248	-	-	- (aa)	-	-
ENST00000523921	HNRNPH1-247	584	-	ENSP00000429270	194 (aa)	-	H0YBD7
ENST00000510411	HNRNPH1-216	2105	XM_006714863	ENSP00000426275	429 (aa)	XP_006714926	E9PCY7
ENST00000519056	HNRNPH1-232	530	-	ENSP00000430970	155 (aa)	-	E5RGV0
ENST00000510431	HNRNPH1-217	620	-	ENSP00000423140	161 (aa)	-	D6R9T0
ENST00000519455	HNRNPH1-233	451	-	-	- (aa)	-	-
ENST00000521790	HNRNPH1-241	549	-	ENSP00000430156	100 (aa)	-	E5RGH4
ENST00000524180	HNRNPH1-249	997	-	-	- (aa)	-	-
ENST00000506721	HNRNPH1-214	602	-	ENSP00000420850	171 (aa)	-	D6RDU3
ENST00000503105	HNRNPH1-207	559	-	ENSP00000427408	164 (aa)	-	D6RIT2
ENST00000508103	HNRNPH1-215	610	-	ENSP00000425732	172 (aa)	-	D6RJ04
ENST00000502904	HNRNPH1-206	2913	-	-	- (aa)	-	-
ENST00000329433	HNRNPH1-201	2114	XM_005265895	ENSP00000327539	472 (aa)	XP_005265952	G8JLB6
ENST00000523137	HNRNPH1-245	1563	-	ENSP00000427986	166 (aa)	-	E7EN40
ENST00000523136	HNRNPH1-244	143	-	ENSP00000430445	48 (aa)	-	H0YBW2
ENST00000356731	HNRNPH1-202	3667	XM_017009415	ENSP00000349168	449 (aa)	XP_016864904	P31943
ENST00000512273	HNRNPH1-219	501	-	ENSP00000427351	40 (aa)	-	D6R9D3
ENST00000518602	HNRNPH1-230	291	-	-	- (aa)	-	-
ENST00000515158	HNRNPH1-225	850	-	ENSP00000421695	130 (aa)	-	D6RAM1
ENST00000630639	HNRNPH1-250	123	-	ENSP00000486889	40 (aa)	-	D6R9D3
ENST00000504779	HNRNPH1-211	792	-	ENSP00000422955	40 (aa)	-	D6R9D3
ENST00000519943	HNRNPH1-235	748	-	-	- (aa)	-	-
ENST00000510678	HNRNPH1-218	1996	-	ENSP00000425851	184 (aa)	-	D6RIH9
ENST00000524179	HNRNPH1-248	598	-	-	- (aa)	-	-
ENST00000520415	HNRNPH1-237	620	-	-	- (aa)	-	-
ENST00000515446	HNRNPH1-226	368	-	-	- (aa)	-	-
ENST00000515481	HNRNPH1-227	5564	-	-	- (aa)	-	-
ENST00000505087	HNRNPH1-212	592	-	-	- (aa)	-	-
ENST00000513225	HNRNPH1-220	805	-	ENSP00000426518	163 (aa)	-	D6RFM3
ENST00000514332	HNRNPH1-223	2444	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000169045's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000169045	Rest	7E-7	27126917
ENSG00000169045	Rest	1E-6	27126917

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000169045	rs113817606	5	179629159	C	Daytime sleep phenotypes	27126917	[0.68-1.56] unit decrease	1.117	EFO_0007828
ENSG00000169045	rs61078164	5	179629110	G	Daytime sleep phenotypes	27126917	[0.46-1.08] unit decrease	0.7744	EFO_0007828

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169045's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000169045	HNRNPH1	86	37.975	ENSG00000183808	RBM12B	93	40.000
ENSG00000169045	HNRNPH1	100	51.485	ENSG00000132463	GRSF1	98	58.621
ENSG00000169045	HNRNPH1	94	33.333	ENSG00000244462	RBM12	63	31.818
ENSG00000169045	HNRNPH1	100	86.000	ENSG00000169813	HNRNPF	100	77.551
ENSG00000169045	HNRNPH1	95	81.579	ENSG00000096746	HNRNPH3	99	59.673
ENSG00000169045	HNRNPH1	70	33.898	ENSG00000075856	SART3	51	32.895
ENSG00000169045	HNRNPH1	100	98.000	ENSG00000126945	HNRNPH2	100	96.214

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169045	HNRNPH1	100	100.000	ENSAMEG00000008888	HNRNPH1	100	98.729	Ailuropoda_melanoleuca
ENSG00000169045	HNRNPH1	100	98.000	ENSAMEG00000018738	HNRNPH2	100	96.437	Ailuropoda_melanoleuca
ENSG00000169045	HNRNPH1	100	100.000	ENSAPLG00000010309	-	90	86.710	Anas_platyrhynchos
ENSG00000169045	HNRNPH1	100	100.000	ENSANAG00000035312	HNRNPH1	100	100.000	Aotus_nancymaae
ENSG00000169045	HNRNPH1	100	98.000	ENSBTAG00000007499	HNRNPH2	100	96.214	Bos_taurus
ENSG00000169045	HNRNPH1	100	100.000	ENSBTAG00000009389	HNRNPH1	100	100.000	Bos_taurus
ENSG00000169045	HNRNPH1	99	95.798	ENSCJAG00000042023	-	99	97.445	Callithrix_jacchus
ENSG00000169045	HNRNPH1	100	100.000	ENSCJAG00000009931	-	100	100.000	Callithrix_jacchus
ENSG00000169045	HNRNPH1	100	98.000	ENSCJAG00000004908	HNRNPH2	100	96.214	Callithrix_jacchus
ENSG00000169045	HNRNPH1	92	94.413	ENSCAFG00000023462	-	100	94.301	Canis_familiaris
ENSG00000169045	HNRNPH1	100	98.000	ENSCAFG00000017693	HNRNPH2	100	96.214	Canis_familiaris
ENSG00000169045	HNRNPH1	100	100.000	ENSCAFG00000000336	HNRNPH1	100	97.550	Canis_familiaris
ENSG00000169045	HNRNPH1	100	100.000	ENSCAFG00020002712	HNRNPH1	100	96.196	Canis_lupus_dingo
ENSG00000169045	HNRNPH1	100	98.000	ENSCAFG00020007379	HNRNPH2	100	96.214	Canis_lupus_dingo
ENSG00000169045	HNRNPH1	100	100.000	ENSCHIG00000014979	-	100	94.565	Capra_hircus
ENSG00000169045	HNRNPH1	100	98.000	ENSCHIG00000019883	-	100	96.214	Capra_hircus
ENSG00000169045	HNRNPH1	100	98.000	ENSCHIG00000010404	-	100	95.991	Capra_hircus
ENSG00000169045	HNRNPH1	100	100.000	ENSCHIG00000021285	HNRNPH1	94	94.931	Capra_hircus
ENSG00000169045	HNRNPH1	100	100.000	ENSTSYG00000006417	HNRNPH1	96	95.900	Carlito_syrichta
ENSG00000169045	HNRNPH1	100	95.135	ENSCAPG00000007268	-	100	86.247	Cavia_aperea
ENSG00000169045	HNRNPH1	97	100.000	ENSCAPG00000007470	-	100	97.043	Cavia_aperea
ENSG00000169045	HNRNPH1	100	95.385	ENSCAPG00000010920	-	100	85.326	Cavia_aperea
ENSG00000169045	HNRNPH1	100	95.513	ENSCAPG00000006281	-	100	86.247	Cavia_aperea
ENSG00000169045	HNRNPH1	100	89.796	ENSCAPG00000000003	-	100	83.450	Cavia_aperea
ENSG00000169045	HNRNPH1	100	100.000	ENSCPOG00000001485	-	100	100.000	Cavia_porcellus
ENSG00000169045	HNRNPH1	100	93.077	ENSCPOG00000012889	-	100	83.450	Cavia_porcellus
ENSG00000169045	HNRNPH1	100	96.429	ENSCPOG00000034133	-	99	91.304	Cavia_porcellus
ENSG00000169045	HNRNPH1	100	98.000	ENSCPOG00000012405	HNRNPH2	100	96.214	Cavia_porcellus
ENSG00000169045	HNRNPH1	100	94.595	ENSCPOG00000039226	-	100	86.014	Cavia_porcellus
ENSG00000169045	HNRNPH1	100	100.000	ENSCCAG00000026563	HNRNPH1	100	100.000	Cebus_capucinus
ENSG00000169045	HNRNPH1	100	100.000	ENSCATG00000034747	HNRNPH1	100	100.000	Cercocebus_atys
ENSG00000169045	HNRNPH1	99	89.474	ENSCATG00000029532	-	100	84.298	Cercocebus_atys
ENSG00000169045	HNRNPH1	100	84.524	ENSCLAG00000014408	-	100	75.724	Chinchilla_lanigera
ENSG00000169045	HNRNPH1	100	98.000	ENSCLAG00000001969	-	100	95.991	Chinchilla_lanigera
ENSG00000169045	HNRNPH1	100	100.000	ENSCLAG00000013617	HNRNPH1	100	100.000	Chinchilla_lanigera
ENSG00000169045	HNRNPH1	100	98.000	ENSCSAG00000000055	HNRNPH2	100	95.991	Chlorocebus_sabaeus
ENSG00000169045	HNRNPH1	100	100.000	ENSCSAG00000008415	HNRNPH1	95	98.511	Chlorocebus_sabaeus
ENSG00000169045	HNRNPH1	93	97.030	ENSCHOG00000001614	-	94	90.588	Choloepus_hoffmanni
ENSG00000169045	HNRNPH1	100	100.000	ENSCHOG00000003841	-	100	97.039	Choloepus_hoffmanni
ENSG00000169045	HNRNPH1	100	100.000	ENSCPBG00000009511	-	84	87.253	Chrysemys_picta_bellii
ENSG00000169045	HNRNPH1	100	65.347	ENSCING00000001798	-	98	49.728	Ciona_intestinalis
ENSG00000169045	HNRNPH1	100	100.000	ENSCANG00000035917	-	100	96.216	Colobus_angolensis_palliatus
ENSG00000169045	HNRNPH1	100	100.000	ENSCANG00000040549	-	100	100.000	Colobus_angolensis_palliatus
ENSG00000169045	HNRNPH1	100	87.027	ENSCANG00000033152	-	95	79.681	Colobus_angolensis_palliatus
ENSG00000169045	HNRNPH1	100	98.000	ENSCGRG00001008855	Hnrnph2	100	95.768	Cricetulus_griseus_chok1gshd
ENSG00000169045	HNRNPH1	100	85.714	ENSCGRG00001017155	-	99	83.810	Cricetulus_griseus_chok1gshd
ENSG00000169045	HNRNPH1	100	100.000	ENSCGRG00001013538	Hnrnph1	100	99.777	Cricetulus_griseus_chok1gshd
ENSG00000169045	HNRNPH1	100	85.714	ENSCGRG00000011511	-	100	71.795	Cricetulus_griseus_crigri
ENSG00000169045	HNRNPH1	100	98.000	ENSCGRG00000003693	Hnrnph2	100	95.768	Cricetulus_griseus_crigri
ENSG00000169045	HNRNPH1	100	100.000	ENSCGRG00000015591	Hnrnph1	100	99.279	Cricetulus_griseus_crigri
ENSG00000169045	HNRNPH1	100	98.000	ENSDNOG00000015963	HNRNPH2	100	96.437	Dasypus_novemcinctus
ENSG00000169045	HNRNPH1	100	100.000	ENSDNOG00000046593	-	96	93.013	Dasypus_novemcinctus
ENSG00000169045	HNRNPH1	100	69.744	ENSDNOG00000038649	-	96	67.126	Dasypus_novemcinctus
ENSG00000169045	HNRNPH1	100	100.000	ENSDORG00000005453	Hnrnph1	100	100.000	Dipodomys_ordii
ENSG00000169045	HNRNPH1	100	98.000	ENSDORG00000026166	Hnrnph2	100	95.768	Dipodomys_ordii
ENSG00000169045	HNRNPH1	100	100.000	ENSETEG00000011303	HNRNPH1	96	91.868	Echinops_telfairi
ENSG00000169045	HNRNPH1	100	98.000	ENSETEG00000008416	HNRNPH2	100	96.659	Echinops_telfairi
ENSG00000169045	HNRNPH1	100	65.000	ENSEBUG00000009078	-	92	64.516	Eptatretus_burgeri
ENSG00000169045	HNRNPH1	100	67.000	ENSEBUG00000002680	-	88	58.824	Eptatretus_burgeri
ENSG00000169045	HNRNPH1	100	98.000	ENSEASG00005019595	HNRNPH2	100	96.437	Equus_asinus_asinus
ENSG00000169045	HNRNPH1	100	100.000	ENSEASG00005012642	HNRNPH1	100	100.000	Equus_asinus_asinus
ENSG00000169045	HNRNPH1	100	98.000	ENSECAG00000023575	HNRNPH2	100	96.437	Equus_caballus
ENSG00000169045	HNRNPH1	100	100.000	ENSECAG00000014429	HNRNPH1	100	100.000	Equus_caballus
ENSG00000169045	HNRNPH1	99	93.773	ENSEEUG00000013364	-	100	98.061	Erinaceus_europaeus
ENSG00000169045	HNRNPH1	100	100.000	ENSEEUG00000010991	-	100	99.010	Erinaceus_europaeus
ENSG00000169045	HNRNPH1	100	98.000	ENSFCAG00000015400	HNRNPH2	100	96.214	Felis_catus
ENSG00000169045	HNRNPH1	100	100.000	ENSFCAG00000001204	HNRNPH1	100	100.000	Felis_catus
ENSG00000169045	HNRNPH1	100	100.000	ENSFALG00000007747	-	97	78.600	Ficedula_albicollis
ENSG00000169045	HNRNPH1	100	94.878	ENSFDAG00000014800	-	100	94.878	Fukomys_damarensis
ENSG00000169045	HNRNPH1	100	100.000	ENSFDAG00000019725	HNRNPH1	100	94.086	Fukomys_damarensis
ENSG00000169045	HNRNPH1	100	94.000	ENSFDAG00000021452	-	94	90.703	Fukomys_damarensis
ENSG00000169045	HNRNPH1	100	100.000	ENSGALG00000031120	HNRNPH2	96	86.681	Gallus_gallus
ENSG00000169045	HNRNPH1	100	100.000	ENSGAGG00000020626	-	84	87.033	Gopherus_agassizii
ENSG00000169045	HNRNPH1	100	100.000	ENSGGOG00000025844	HNRNPH1	100	100.000	Gorilla_gorilla
ENSG00000169045	HNRNPH1	100	86.000	ENSGGOG00000040613	-	100	75.424	Gorilla_gorilla
ENSG00000169045	HNRNPH1	100	100.000	ENSHGLG00000018565	-	100	100.000	Heterocephalus_glaber_female
ENSG00000169045	HNRNPH1	100	98.000	ENSHGLG00000001154	HNRNPH2	100	95.546	Heterocephalus_glaber_female
ENSG00000169045	HNRNPH1	100	89.796	ENSHGLG00000016084	-	95	74.940	Heterocephalus_glaber_female
ENSG00000169045	HNRNPH1	96	85.185	ENSHGLG00100016193	-	91	77.902	Heterocephalus_glaber_male
ENSG00000169045	HNRNPH1	100	89.796	ENSHGLG00100005640	-	96	74.217	Heterocephalus_glaber_male
ENSG00000169045	HNRNPH1	100	100.000	ENSHGLG00100010620	HNRNPH1	100	98.861	Heterocephalus_glaber_male
ENSG00000169045	HNRNPH1	100	98.000	ENSHGLG00100005864	-	100	92.650	Heterocephalus_glaber_male
ENSG00000169045	HNRNPH1	100	98.000	ENSSTOG00000029028	HNRNPH2	100	96.437	Ictidomys_tridecemlineatus
ENSG00000169045	HNRNPH1	100	100.000	ENSSTOG00000016376	HNRNPH1	100	100.000	Ictidomys_tridecemlineatus
ENSG00000169045	HNRNPH1	99	76.768	ENSJJAG00000009857	-	100	71.023	Jaculus_jaculus
ENSG00000169045	HNRNPH1	100	96.000	ENSJJAG00000004850	-	100	94.432	Jaculus_jaculus
ENSG00000169045	HNRNPH1	100	100.000	ENSJJAG00000016203	Hnrnph1	100	100.000	Jaculus_jaculus
ENSG00000169045	HNRNPH1	99	85.714	ENSJJAG00000016174	-	100	83.296	Jaculus_jaculus
ENSG00000169045	HNRNPH1	100	99.000	ENSLACG00000004394	-	95	83.111	Latimeria_chalumnae
ENSG00000169045	HNRNPH1	98	68.085	ENSLAFG00000027079	-	96	56.442	Loxodonta_africana
ENSG00000169045	HNRNPH1	100	100.000	ENSLAFG00000015766	-	100	99.555	Loxodonta_africana
ENSG00000169045	HNRNPH1	97	96.889	ENSMFAG00000042514	-	96	96.691	Macaca_fascicularis
ENSG00000169045	HNRNPH1	99	88.235	ENSMFAG00000033989	-	96	80.714	Macaca_fascicularis
ENSG00000169045	HNRNPH1	100	100.000	ENSMFAG00000028267	HNRNPH1	100	100.000	Macaca_fascicularis
ENSG00000169045	HNRNPH1	93	88.462	ENSMFAG00000040187	-	98	61.926	Macaca_fascicularis
ENSG00000169045	HNRNPH1	100	100.000	ENSMMUG00000010843	HNRNPH1	100	100.000	Macaca_mulatta
ENSG00000169045	HNRNPH1	100	98.000	ENSMMUG00000019580	HNRNPH2	100	96.214	Macaca_mulatta
ENSG00000169045	HNRNPH1	100	88.000	ENSMMUG00000045060	-	100	81.898	Macaca_mulatta
ENSG00000169045	HNRNPH1	99	88.235	ENSMNEG00000016707	-	100	77.704	Macaca_nemestrina
ENSG00000169045	HNRNPH1	100	100.000	ENSMNEG00000032375	HNRNPH1	100	100.000	Macaca_nemestrina
ENSG00000169045	HNRNPH1	97	85.556	ENSMLEG00000027448	-	96	66.304	Mandrillus_leucophaeus
ENSG00000169045	HNRNPH1	99	89.474	ENSMLEG00000041660	-	100	84.298	Mandrillus_leucophaeus
ENSG00000169045	HNRNPH1	100	100.000	ENSMLEG00000040142	-	100	100.000	Mandrillus_leucophaeus
ENSG00000169045	HNRNPH1	100	100.000	ENSMGAG00000007328	-	94	86.214	Meleagris_gallopavo
ENSG00000169045	HNRNPH1	100	100.000	ENSMAUG00000012959	Hnrnph1	100	99.777	Mesocricetus_auratus
ENSG00000169045	HNRNPH1	100	98.000	ENSMAUG00000001882	Hnrnph2	100	95.768	Mesocricetus_auratus
ENSG00000169045	HNRNPH1	100	100.000	ENSMICG00000034553	-	96	90.330	Microcebus_murinus
ENSG00000169045	HNRNPH1	100	100.000	ENSMICG00000033979	-	100	100.000	Microcebus_murinus
ENSG00000169045	HNRNPH1	100	100.000	ENSMOCG00000020579	Hnrnph1	100	99.777	Microtus_ochrogaster
ENSG00000169045	HNRNPH1	100	98.000	ENSMOCG00000012470	Hnrnph2	100	95.768	Microtus_ochrogaster
ENSG00000169045	HNRNPH1	100	100.000	ENSMODG00000009436	-	100	96.882	Monodelphis_domestica
ENSG00000169045	HNRNPH1	93	58.564	ENSMODG00000024770	-	99	57.292	Monodelphis_domestica
ENSG00000169045	HNRNPH1	91	84.375	ENSMODG00000000008	-	95	76.012	Monodelphis_domestica
ENSG00000169045	HNRNPH1	86	88.050	ENSMODG00000028046	-	100	88.050	Monodelphis_domestica
ENSG00000169045	HNRNPH1	100	98.000	MGP_CAROLIEiJ_G0033396	Hnrnph2	100	95.768	Mus_caroli
ENSG00000169045	HNRNPH1	98	100.000	MGP_CAROLIEiJ_G0016291	-	66	100.000	Mus_caroli
ENSG00000169045	HNRNPH1	100	100.000	ENSMUSG00000007850	Hnrnph1	100	99.777	Mus_musculus
ENSG00000169045	HNRNPH1	100	98.000	ENSMUSG00000045427	Hnrnph2	100	95.768	Mus_musculus
ENSG00000169045	HNRNPH1	100	98.000	MGP_PahariEiJ_G0031936	Hnrnph2	100	95.768	Mus_pahari
ENSG00000169045	HNRNPH1	100	100.000	MGP_PahariEiJ_G0017426	Hnrnph1	100	99.777	Mus_pahari
ENSG00000169045	HNRNPH1	100	98.000	MGP_SPRETEiJ_G0034560	Hnrnph2	100	95.768	Mus_spretus
ENSG00000169045	HNRNPH1	100	100.000	ENSMPUG00000000693	HNRNPH1	100	100.000	Mustela_putorius_furo
ENSG00000169045	HNRNPH1	100	98.000	ENSMPUG00000019139	HNRNPH2	100	96.437	Mustela_putorius_furo
ENSG00000169045	HNRNPH1	100	100.000	ENSMLUG00000016625	-	100	98.646	Myotis_lucifugus
ENSG00000169045	HNRNPH1	100	87.000	ENSMLUG00000023046	-	99	77.447	Myotis_lucifugus
ENSG00000169045	HNRNPH1	100	98.000	ENSMLUG00000022366	HNRNPH2	100	95.991	Myotis_lucifugus
ENSG00000169045	HNRNPH1	98	72.340	ENSMLUG00000023016	-	94	63.692	Myotis_lucifugus
ENSG00000169045	HNRNPH1	100	98.000	ENSNGAG00000020504	Hnrnph2	100	95.768	Nannospalax_galili
ENSG00000169045	HNRNPH1	100	90.000	ENSNGAG00000021181	-	100	83.217	Nannospalax_galili
ENSG00000169045	HNRNPH1	100	100.000	ENSNGAG00000014666	Hnrnph1	100	100.000	Nannospalax_galili
ENSG00000169045	HNRNPH1	99	83.838	ENSNLEG00000033978	-	100	73.295	Nomascus_leucogenys
ENSG00000169045	HNRNPH1	100	76.216	ENSNLEG00000033964	-	100	68.065	Nomascus_leucogenys
ENSG00000169045	HNRNPH1	100	100.000	ENSNLEG00000026658	-	100	99.576	Nomascus_leucogenys
ENSG00000169045	HNRNPH1	85	90.244	ENSMEUG00000014575	-	72	80.000	Notamacropus_eugenii
ENSG00000169045	HNRNPH1	94	100.000	ENSOPRG00000003513	HNRNPH1	100	97.345	Ochotona_princeps
ENSG00000169045	HNRNPH1	100	98.000	ENSOPRG00000007985	HNRNPH2	100	96.214	Ochotona_princeps
ENSG00000169045	HNRNPH1	100	100.000	ENSODEG00000007058	-	100	100.000	Octodon_degus
ENSG00000169045	HNRNPH1	100	89.000	ENSODEG00000007170	-	100	75.524	Octodon_degus
ENSG00000169045	HNRNPH1	100	100.000	ENSODEG00000001195	-	100	99.333	Octodon_degus
ENSG00000169045	HNRNPH1	100	100.000	ENSOANG00000010222	HNRNPH1	99	98.762	Ornithorhynchus_anatinus
ENSG00000169045	HNRNPH1	100	98.000	ENSOCUG00000006387	-	100	96.437	Oryctolagus_cuniculus
ENSG00000169045	HNRNPH1	100	100.000	ENSOCUG00000017150	HNRNPH1	100	100.000	Oryctolagus_cuniculus
ENSG00000169045	HNRNPH1	100	98.000	ENSOCUG00000010629	-	100	96.437	Oryctolagus_cuniculus
ENSG00000169045	HNRNPH1	100	100.000	ENSOGAG00000012631	HNRNPH1	100	99.364	Otolemur_garnettii
ENSG00000169045	HNRNPH1	100	98.000	ENSOGAG00000026285	HNRNPH2	100	96.214	Otolemur_garnettii
ENSG00000169045	HNRNPH1	100	98.000	ENSOARG00000010044	HNRNPH2	100	96.214	Ovis_aries
ENSG00000169045	HNRNPH1	100	100.000	ENSOARG00000003368	HNRNPH1	100	100.000	Ovis_aries
ENSG00000169045	HNRNPH1	100	100.000	ENSPPAG00000038325	-	100	99.767	Pan_paniscus
ENSG00000169045	HNRNPH1	93	84.615	ENSPPAG00000028640	-	99	64.537	Pan_paniscus
ENSG00000169045	HNRNPH1	100	98.000	ENSPPAG00000028452	-	100	91.183	Pan_paniscus
ENSG00000169045	HNRNPH1	100	85.000	ENSPPAG00000037145	-	96	68.791	Pan_paniscus
ENSG00000169045	HNRNPH1	100	98.000	ENSPPAG00000041056	-	100	93.764	Pan_paniscus
ENSG00000169045	HNRNPH1	100	100.000	ENSPPRG00000008228	HNRNPH1	100	100.000	Panthera_pardus
ENSG00000169045	HNRNPH1	100	98.000	ENSPPRG00000010941	HNRNPH2	100	96.214	Panthera_pardus
ENSG00000169045	HNRNPH1	100	98.000	ENSPTIG00000001193	HNRNPH2	100	95.768	Panthera_tigris_altaica
ENSG00000169045	HNRNPH1	100	100.000	ENSPTIG00000021552	HNRNPH1	93	100.000	Panthera_tigris_altaica
ENSG00000169045	HNRNPH1	100	100.000	ENSPTRG00000051626	-	100	100.000	Pan_troglodytes
ENSG00000169045	HNRNPH1	99	83.838	ENSPTRG00000047088	-	100	67.614	Pan_troglodytes
ENSG00000169045	HNRNPH1	93	84.615	ENSPTRG00000046132	-	99	64.537	Pan_troglodytes
ENSG00000169045	HNRNPH1	100	87.000	ENSPTRG00000048965	-	100	74.246	Pan_troglodytes
ENSG00000169045	HNRNPH1	99	92.674	ENSPANG00000030505	-	100	77.951	Papio_anubis
ENSG00000169045	HNRNPH1	100	100.000	ENSPANG00000012212	-	100	98.370	Papio_anubis
ENSG00000169045	HNRNPH1	100	100.000	ENSPANG00000013058	HNRNPH1	100	100.000	Papio_anubis
ENSG00000169045	HNRNPH1	100	88.095	ENSPANG00000032578	-	100	80.846	Papio_anubis
ENSG00000169045	HNRNPH1	96	88.889	ENSPANG00000033618	-	99	64.176	Papio_anubis
ENSG00000169045	HNRNPH1	100	100.000	ENSPSIG00000003206	-	91	87.473	Pelodiscus_sinensis
ENSG00000169045	HNRNPH1	100	100.000	ENSPEMG00000018866	Hnrnph1	100	99.777	Peromyscus_maniculatus_bairdii
ENSG00000169045	HNRNPH1	100	98.000	ENSPEMG00000019998	-	100	95.768	Peromyscus_maniculatus_bairdii
ENSG00000169045	HNRNPH1	100	73.529	ENSPMAG00000000757	HNRNPH1	82	63.198	Petromyzon_marinus
ENSG00000169045	HNRNPH1	98	60.204	ENSPCIG00000029846	-	83	49.839	Phascolarctos_cinereus
ENSG00000169045	HNRNPH1	100	100.000	ENSPCIG00000007921	HNRNPH1	100	98.517	Phascolarctos_cinereus
ENSG00000169045	HNRNPH1	96	81.667	ENSPCIG00000027236	-	93	75.658	Phascolarctos_cinereus
ENSG00000169045	HNRNPH1	100	100.000	ENSPPYG00000016121	HNRNPH1	100	98.667	Pongo_abelii
ENSG00000169045	HNRNPH1	100	98.000	ENSPPYG00000020553	HNRNPH2	100	96.214	Pongo_abelii
ENSG00000169045	HNRNPH1	96	100.000	ENSPCAG00000006715	HNRNPH1	99	96.439	Procavia_capensis
ENSG00000169045	HNRNPH1	100	98.000	ENSPCAG00000003333	HNRNPH2	100	95.991	Procavia_capensis
ENSG00000169045	HNRNPH1	100	100.000	ENSPCOG00000016762	HNRNPH1	100	100.000	Propithecus_coquereli
ENSG00000169045	HNRNPH1	100	98.000	ENSPVAG00000001571	HNRNPH2	100	96.437	Pteropus_vampyrus
ENSG00000169045	HNRNPH1	100	100.000	ENSPVAG00000007670	HNRNPH1	100	80.139	Pteropus_vampyrus
ENSG00000169045	HNRNPH1	100	98.000	ENSRNOG00000011661	Hnrnph2	100	95.546	Rattus_norvegicus
ENSG00000169045	HNRNPH1	100	100.000	ENSRNOG00000003399	Hnrnph1	100	100.000	Rattus_norvegicus
ENSG00000169045	HNRNPH1	100	94.615	ENSRBIG00000038807	HNRNPH2	100	90.646	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	99.000	ENSRBIG00000022323	-	100	94.406	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	86.000	ENSRBIG00000015941	-	100	72.326	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	95.000	ENSRBIG00000032973	-	99	72.158	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	97.959	ENSRBIG00000040052	-	100	93.987	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	100.000	ENSRBIG00000031870	-	100	98.370	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	96	92.593	ENSRBIG00000036754	-	98	63.956	Rhinopithecus_bieti
ENSG00000169045	HNRNPH1	100	98.000	ENSRROG00000041773	-	100	93.939	Rhinopithecus_roxellana
ENSG00000169045	HNRNPH1	100	86.000	ENSRROG00000040571	-	97	76.628	Rhinopithecus_roxellana
ENSG00000169045	HNRNPH1	100	98.000	ENSRROG00000021687	-	100	94.172	Rhinopithecus_roxellana
ENSG00000169045	HNRNPH1	100	100.000	ENSRROG00000035613	-	100	98.004	Rhinopithecus_roxellana
ENSG00000169045	HNRNPH1	100	95.918	ENSRROG00000034942	-	100	92.791	Rhinopithecus_roxellana
ENSG00000169045	HNRNPH1	100	100.000	ENSSBOG00000022306	HNRNPH1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000169045	HNRNPH1	98	58.163	ENSSHAG00000017269	-	99	49.032	Sarcophilus_harrisii
ENSG00000169045	HNRNPH1	100	77.000	ENSSHAG00000012803	-	96	65.055	Sarcophilus_harrisii
ENSG00000169045	HNRNPH1	100	100.000	ENSSHAG00000018204	HNRNPH1	100	98.420	Sarcophilus_harrisii
ENSG00000169045	HNRNPH1	100	80.851	ENSSHAG00000006390	-	99	78.235	Sarcophilus_harrisii
ENSG00000169045	HNRNPH1	100	98.000	ENSSARG00000014182	HNRNPH2	100	96.437	Sorex_araneus
ENSG00000169045	HNRNPH1	100	97.000	ENSSARG00000003024	HNRNPH1	96	90.995	Sorex_araneus
ENSG00000169045	HNRNPH1	99	84.892	ENSSPUG00000002417	-	96	73.964	Sphenodon_punctatus
ENSG00000169045	HNRNPH1	100	100.000	ENSSPUG00000012604	-	92	93.434	Sphenodon_punctatus
ENSG00000169045	HNRNPH1	100	98.000	ENSSSCG00000033161	HNRNPH2	100	96.214	Sus_scrofa
ENSG00000169045	HNRNPH1	100	100.000	ENSSSCG00000014022	HNRNPH1	100	100.000	Sus_scrofa
ENSG00000169045	HNRNPH1	100	100.000	ENSTGUG00000001085	-	100	92.857	Taeniopygia_guttata
ENSG00000169045	HNRNPH1	100	66.981	ENSTNIG00000008997	HNRNPH1	100	64.364	Tetraodon_nigroviridis
ENSG00000169045	HNRNPH1	100	100.000	ENSTBEG00000012210	HNRNPH1	88	96.000	Tupaia_belangeri
ENSG00000169045	HNRNPH1	100	100.000	ENSTTRG00000000470	HNRNPH1	85	100.000	Tursiops_truncatus
ENSG00000169045	HNRNPH1	100	98.000	ENSTTRG00000012786	HNRNPH2	100	96.214	Tursiops_truncatus
ENSG00000169045	HNRNPH1	100	98.000	ENSUAMG00000021296	HNRNPH2	100	96.437	Ursus_americanus
ENSG00000169045	HNRNPH1	100	100.000	ENSUAMG00000011445	HNRNPH1	100	100.000	Ursus_americanus
ENSG00000169045	HNRNPH1	100	100.000	ENSUMAG00000024131	HNRNPH1	100	100.000	Ursus_maritimus
ENSG00000169045	HNRNPH1	100	98.000	ENSUMAG00000012146	HNRNPH2	100	96.437	Ursus_maritimus
ENSG00000169045	HNRNPH1	95	100.000	ENSVPAG00000007485	HNRNPH1	100	90.433	Vicugna_pacos
ENSG00000169045	HNRNPH1	100	98.000	ENSVVUG00000005267	HNRNPH2	100	96.214	Vulpes_vulpes
ENSG00000169045	HNRNPH1	100	100.000	ENSVVUG00000001397	HNRNPH1	100	100.000	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	16946708.	IDA	Function
GO:0005515	protein binding	9111328.16946708.17289661.24910439.24965446.	IPI	Function
GO:0005634	nucleus	24910439.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006396	RNA processing	7499401.	TAS	Process
GO:0008266	poly(U) RNA binding	7499401.	TAS	Function
GO:0008543	fibroblast growth factor receptor signaling pathway	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016070	RNA metabolic process	-	TAS	Process
GO:0043484	regulation of RNA splicing	16946708.	IDA	Process
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21068389	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	J Biol Chem	2011 Feb 4	Stark M	doi: 10.1074/jbc.M110.163444
27621578	Protein and gene expression characteristics of heterogeneous nuclear ribonucleoprotein H1 in esophageal squamous cell carcinoma.	World J Gastroenterol	2016 Aug 28	Sun YL	doi: 10.3748/wjg.v22.i32.7322.
29252188	Serum exosomal hnRNPH1 mRNA as a novel marker for hepatocellular carcinoma.	Clin Chem Lab Med	2018 Feb 23	Xu H	doi: 10.1515/cclm-2017-0327.
20145135	Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription.	Cancer Res	2010 Feb 15	Rauch J	doi: 10.1158/0008-5472.CAN-09-2740
19425502	[Colorectal cancer 2D-proteomics: identification of altered protein expression].	Mol Biol (Mosk)	2009 Mar-Apr	Krasnov GS	-
21194727	The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis.	Hum Pathol	2011 Mar	Hope NR	doi: 10.1016/j.humpath.2010.08.006
28844715	Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.	Cancer Lett	2017 Nov 1	Datta A	doi: 10.1016/j.canlet.2017.08.020

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	179623061	Missense_Mutation	novel	D25N	0.24	zf-RNPHF
BLCA	chr5	179617862	Silent	novel	T286T	0.35
BLCA	chr5	179620914	Missense_Mutation	novel	E125D	0.42
BLCA	chr5	179621038	Splice_Region	novel		0.09
BLCA	chr5	179621026	Missense_Mutation	novel	S88L	0.1
BLCA	chr5	179621120	Intron	novel		0.33
BLCA	chr5	179617816	Missense_Mutation	novel	E302K	0.27
BRCA	chr5	179617635	Silent	NA	L312L	0.22
BRCA	chr5	179616880	Missense_Mutation	NA	G399D	0.24
BRCA	chr5	179617054	Missense_Mutation	NA	Y372N	0.41
BRCA	chr5	179616939	Silent	NA	L379L	0.25
CESC	chr5	179614948	3'UTR	novel		0.24
CESC	chr5	179623118	Missense_Mutation	NA	E6K	0.59
CESC	chr5	179618243	Missense_Mutation	NA	R206Q	0.28
CESC	chr5	179617565	Missense_Mutation	novel	A336T	0.08
CESC	chr5	179615569	Missense_Mutation	novel	D443N	0.43
COAD	chr5	179617625	Silent	NA	R316R	0.32
COAD	chr5	179617574	Missense_Mutation	NA	V333I	0.3
COAD	chr5	179618244	Missense_Mutation	NA	R206W	0.29
COAD	chr5	179618273	Missense_Mutation	novel	D196A	0.11
COAD	chr5	179617065	Missense_Mutation	novel	S368I	0.06
COAD	chr5	179619281	Missense_Mutation	NA	R175I	0.36
COAD	chr5	179616888	Missense_Mutation	NA	M396I	0.1
COAD	chr5	179621284	Missense_Mutation	novel	L71M	0.04	zf-RNPHF
COAD	chr5	179618244	Missense_Mutation	NA	R206W	0.37
ESCA	chr5	179621042	Splice_Region	NA		0.24
GBM	chr5	179618271	Missense_Mutation	novel	P197S	0.12
HNSC	chr5	179619281	Frame_Shift_Del	novel	*E174Nfs7**	0.26
HNSC	chr5	179621344	Missense_Mutation	novel	G51C	0.13	zf-RNPHF
KIRC	chr5	179617557	Frame_Shift_Del	novel	*H338Rfs56**	0.06
KIRC	chr5	179620902	Silent	NA	Q129Q	0.25
KIRC	chr5	179623063	Missense_Mutation	NA	A24V	0.35	zf-RNPHF
KIRC	chr5	179614843	3'UTR	novel		0.22
KIRC	chr5	179618233	Silent	novel	P209P	0.19
KIRP	chr5	179623243	5'UTR	novel		0.25
KIRP	chr5	179621120	Intron	novel		0.35
LGG	chr5	179616154	Silent	rs115293737	Y424Y	0.13
LGG	chr5	179615595	Missense_Mutation	novel	D434G	0.37
LIHC	chr5	179619346	Silent	novel	G153G	0.41
LIHC	chr5	179616936	Missense_Mutation	NA	F380L	0.34
LIHC	chr5	179620995	Missense_Mutation	NA	K98N	0.25
LUAD	chr5	179623069	Missense_Mutation	NA	C22Y	0.26	zf-RNPHF
LUAD	chr5	179618154	Missense_Mutation	NA	Y236N	0.16
LUAD	chr5	179621374	Missense_Mutation	novel	Q41E	0.11	zf-RNPHF
LUAD	chr5	179618243	Missense_Mutation	NA	R206P	0.15
LUAD	chr5	179617534	Nonsense_Mutation	NA	S346*	0.07
LUAD	chr5	179621120	Intron	novel		0.12
LUSC	chr5	179617869	Missense_Mutation	novel	Q284R	0.15
LUSC	chr5	179616914	Missense_Mutation	novel	S388C	0.13
LUSC	chr5	179617924	Missense_Mutation	novel	Y266H	0.64
LUSC	chr5	179621219	Intron	novel		0.33
LUSC	chr5	179618210	Missense_Mutation	novel	R217T	0.12
OV	chr5	179620893	Splice_Region	novel	S132S	0.1
OV	chr5	179618223	Missense_Mutation	novel	P213S	0.07
OV	chr5	179617586	Missense_Mutation	novel	G329C	0.09
OV	chr5	179620893	Splice_Region	novel	S132S	0.17
PAAD	chr5	179617071	Missense_Mutation	novel	G366E	0.23
PAAD	chr5	179617892	Silent	rs78795662	Y276Y	0.26
PRAD	chr5	179617642	Frame_Shift_Ins	novel	*S310Ffs11**	0.3
PRAD	chr5	179616910	Missense_Mutation	rs764732453	G389D	0.19
READ	chr5	179618264	Missense_Mutation	NA	R199Q	0.26
READ	chr5	179618225	Missense_Mutation	NA	R212K	0.54
READ	chr5	179617933	Splice_Site	novel	X263_splice	0.34
READ	chr5	179617101	Missense_Mutation	novel	Y356S	0.08
SARC	chr5	179620882	Splice_Site	novel	X131_splice	0.07
SKCM	chr5	179623093	Missense_Mutation	NA	K14T	0.32	zf-RNPHF
SKCM	chr5	179617566	Silent	rs757132093	F335F	0.35
SKCM	chr5	179621193	Intron	novel		0.11
SKCM	chr5	179621166	Intron	novel		0.39
SKCM	chr5	179616148	Silent	rs769953300	G426G	0.49
SKCM	chr5	179617566	Silent	rs757132093	F335F	0.45
SKCM	chr5	179619360	Missense_Mutation	novel	G149W	0.43
STAD	chr5	179616884	Missense_Mutation	novel	G398R	0.18
STAD	chr5	179617891	Missense_Mutation	NA	G277R	0.22
STAD	chr5	179615577	Missense_Mutation	NA	N440I	0.19
STAD	chr5	179617643	Frame_Shift_Del	novel	*S310Hfs6**	0.4
STAD	chr5	179623040	Frame_Shift_Del	NA	*S32Lfs40**	0.16	zf-RNPHF
STAD	chr5	179618187	Nonsense_Mutation	NA	G225*	0.13
UCEC	chr5	179623244	5'UTR	novel		0.33
UCEC	chr5	179623200	5'UTR	novel		0.11
UCEC	chr5	179614530	3'UTR	novel		0.12
UCEC	chr5	179615545	Splice_Site	NA		0.3
UCEC	chr5	179614875	3'UTR	novel		0.35
UCEC	chr5	179618230	Nonsense_Mutation	novel	Y210*	0.19
UCEC	chr5	179618264	Missense_Mutation	NA	R199L	0.34
UCEC	chr5	179618231	Missense_Mutation	novel	Y210C	0.32
UCEC	chr5	179621171	Intron	novel		0.05
UCEC	chr5	179623211	5'UTR	novel		0.12
UCEC	chr5	179623073	Missense_Mutation	novel	S21P	0.25	zf-RNPHF
UCEC	chr5	179614445	3'UTR	novel		0.36
UCEC	chr5	179616919	Missense_Mutation	novel	G386E	0.15
UCEC	chr5	179614464	3'UTR	novel		0.21
UCEC	chr5	179617036	Intron	novel		0.24
UCEC	chr5	179617889	Silent	novel	G277G	0.44
UCEC	chr5	179614372	3'UTR	novel		0.47
UCEC	chr5	179614948	3'UTR	novel		0.42
UCEC	chr5	179617571	Missense_Mutation	novel	E334K	0.39
UCEC	chr5	179617896	Missense_Mutation	novel	R275I	0.55
UCEC	chr5	179618314	Missense_Mutation	novel	E182D	0.39
UCEC	chr5	179618210	Missense_Mutation	NA	R217I	0.43
UCEC	chr5	179614401	3'UTR	novel		0.19
UCEC	chr5	179621172	Intron	novel		0.21
UCEC	chr5	179614348	3'UTR	novel		0.34
UCEC	chr5	179619297	Missense_Mutation	novel	K170Q	0.35
UCEC	chr5	179614914	3'UTR	rs750283108		0.43
UCEC	chr5	179614382	3'UTR	novel		0.33
UCEC	chr5	179620913	Nonsense_Mutation	novel	E126*	0.38
UCEC	chr5	179623085	Missense_Mutation	novel	G17C	0.38	zf-RNPHF
UCEC	chr5	179614567	3'UTR	novel		0.31
UCEC	chr5	179617514	Nonsense_Mutation	novel	Q353*	0.24
UCEC	chr5	179621065	Intron	novel		0.2
UCEC	chr5	179614915	3'UTR	rs544306478		0.31
UCEC	chr5	179616944	Nonsense_Mutation	novel	E378*	0.29
UCEC	chr5	179614459	3'UTR	novel		0.06
UCEC	chr5	179619406	Splice_Region	rs753187962	G133G	0.36
UCEC	chr5	179623257	5'UTR	novel		0.33
UCEC	chr5	179618243	Missense_Mutation	novel	R206L	0.37
UCEC	chr5	179618278	Missense_Mutation	NA	H194Q	0.25
UCEC	chr5	179616201	Frame_Shift_Ins	novel	*G409Rfs35**	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	AMP	0.589	2.1944e-60
KIRP	AMP	0.1146	0.069756
KIRP	DEL	0.0347	0.11554
LUAD	AMP	0.1802	0.24967
LUSC	DEL	0.5948	0.002071
MESO	DEL	0.1149	0.20184
PRAD	AMP	0.0346	0.16448
SKCM	AMP	0.1253	0.23703
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
THYM	0.013	Kaplan-Meier Survival Analysis
KIRC	0.017	Kaplan-Meier Survival Analysis
STAD	0.023	Kaplan-Meier Survival Analysis
SARC	0.022	Kaplan-Meier Survival Analysis
ACC	0.00017	Kaplan-Meier Survival Analysis
HNSC	0.0051	Kaplan-Meier Survival Analysis
SKCM	0.0051	Kaplan-Meier Survival Analysis
PRAD	0.014	Kaplan-Meier Survival Analysis
KIRP	0.037	Kaplan-Meier Survival Analysis
PAAD	0.0057	Kaplan-Meier Survival Analysis
PCPG	0.0089	Kaplan-Meier Survival Analysis
BLCA	0.0031	Kaplan-Meier Survival Analysis
READ	0.0001	Kaplan-Meier Survival Analysis
LAML	0.033	Kaplan-Meier Survival Analysis
KICH	0.013	Kaplan-Meier Survival Analysis
GBM	0.041	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742