EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169551 (Gene tree)
Gene ID: 54967
Gene Symbol: CT55
Alias: FLJ20527|CXorf48
Full Name: cancer/testis antigen 55
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 15,292 bases
Position: chrX:135,156,536-135,171,827
Accession: 26047
RBP type: canonical RBP
Summary: CT55 (Cancer/Testis Antigen 55) is a Protein Coding gene. An important paralog of this gene is MOV10.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000343893	S1-like	PF14444.6	1.5e-19	1	2
ENSP00000343893	S1-like	PF14444.6	1.5e-19	2	2
ENSP00000276241	S1-like	PF14444.6	2.2e-19	1	2
ENSP00000276241	S1-like	PF14444.6	2.2e-19	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000276241	CT55-201	1445	XM_005262427	ENSP00000276241	264 (aa)	XP_005262484	Q8WUE5
ENST00000344129	CT55-202	1728	-	ENSP00000343893	242 (aa)	-	Q8WUE5

Gene Model

Click here to download ENSG00000169551's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169551's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169551	CT55	95	69.323	ENSANAG00000025850	CT55	96	67.323	Aotus_nancymaae
ENSG00000169551	CT55	100	71.074	ENSCJAG00000020403	CT55	95	69.444	Callithrix_jacchus
ENSG00000169551	CT55	94	73.387	ENSCCAG00000033288	CT55	96	72.441	Cebus_capucinus
ENSG00000169551	CT55	95	83.200	ENSCATG00000032930	CT55	96	82.677	Cercocebus_atys
ENSG00000169551	CT55	96	89.370	ENSCSAG00000007710	-	96	89.370	Chlorocebus_sabaeus
ENSG00000169551	CT55	94	79.151	ENSCSAG00000007720	-	96	78.409	Chlorocebus_sabaeus
ENSG00000169551	CT55	100	82.197	ENSCANG00000038605	CT55	96	81.890	Colobus_angolensis_palliatus
ENSG00000169551	CT55	58	97.163	ENSGGOG00000028404	-	90	97.163	Gorilla_gorilla
ENSG00000169551	CT55	95	85.600	ENSMFAG00000031424	CT55	96	85.039	Macaca_fascicularis
ENSG00000169551	CT55	95	84.064	ENSMMUG00000018715	CT55	96	83.529	Macaca_mulatta
ENSG00000169551	CT55	95	85.600	ENSMNEG00000037841	CT55	96	85.039	Macaca_nemestrina
ENSG00000169551	CT55	95	82.800	ENSMLEG00000028336	CT55	96	82.283	Mandrillus_leucophaeus
ENSG00000169551	CT55	100	64.198	ENSMICG00000047795	CT55	95	60.558	Microcebus_murinus
ENSG00000169551	CT55	96	93.701	ENSNLEG00000029349	CT55	96	93.701	Nomascus_leucogenys
ENSG00000169551	CT55	99	59.167	ENSOGAG00000007138	CT55	96	59.592	Otolemur_garnettii
ENSG00000169551	CT55	74	97.207	ENSPPAG00000001184	-	100	97.207	Pan_paniscus
ENSG00000169551	CT55	65	89.474	ENSPTRG00000022296	CT55	100	89.474	Pan_troglodytes
ENSG00000169551	CT55	100	97.934	ENSPTRG00000050752	CT55	100	97.727	Pan_troglodytes
ENSG00000169551	CT55	94	84.141	ENSPANG00000012503	CT55	95	83.550	Papio_anubis
ENSG00000169551	CT55	96	92.520	ENSPPYG00000020744	CT55	96	92.520	Pongo_abelii
ENSG00000169551	CT55	100	63.223	ENSPCOG00000015916	CT55	96	61.811	Propithecus_coquereli
ENSG00000169551	CT55	99	44.583	ENSRNOG00000061094	LOC100360296	87	46.635	Rattus_norvegicus
ENSG00000169551	CT55	99	49.793	ENSRBIG00000032050	-	95	52.381	Rhinopithecus_bieti
ENSG00000169551	CT55	96	89.224	ENSRBIG00000036226	-	96	89.224	Rhinopithecus_bieti
ENSG00000169551	CT55	100	82.197	ENSRROG00000043598	CT55	96	82.283	Rhinopithecus_roxellana
ENSG00000169551	CT55	86	63.462	ENSTBEG00000009423	-	99	60.699	Tupaia_belangeri
ENSG00000169551	CT55	95	56.332	ENSTBEG00000013745	-	99	56.332	Tupaia_belangeri

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	25416956.	IPI	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18307534	Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage.	Cancer Sci	2008 Apr	Tomiyoshi G	doi: 10.1111/j.1349-7006.2008.00733.x

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chrX	135160552	Missense_Mutation	NA	D95Y	0.32
BRCA	chrX	135171103	Silent	novel	G23G	0.07
BRCA	chrX	135158251	Nonsense_Mutation	NA	S162*	0.17
CESC	chrX	135158244	Missense_Mutation	NA	I164M	0.17
CESC	chrX	135169624	Silent	novel	D83D	0.35
CESC	chrX	135158286	Missense_Mutation	novel	L150F	0.09
COAD	chrX	135171297	5'UTR	novel		0.14
COAD	chrX	135169614	Missense_Mutation	novel	Y87H	0.12
COAD	chrX	135171195	5'UTR	novel		0.34
COAD	chrX	135158206	Missense_Mutation	rs142030219	T177M	0.19
COAD	chrX	135158246	Missense_Mutation	novel	I164F	0.45
ESCA	chrX	135169689	Missense_Mutation	novel	D62Y	0.86
GBM	chrX	135169607	Missense_Mutation	novel	L89S	0.13
GBM	chrX	135158288	Missense_Mutation	novel	L150V	0.28
GBM	chrX	135160467	Missense_Mutation	NA	E123G	0.75
HNSC	chrX	135171173	5'UTR	rs782419674		0.11
HNSC	chrX	135171110	Missense_Mutation	NA	R21Q	0.25
HNSC	chrX	135171111	Nonsense_Mutation	NA	R21*	0.29
HNSC	chrX	135158238	Silent	novel	A166A	0.34
LGG	chrX	135171159	Missense_Mutation	novel	L5M	0.46
LGG	chrX	135169771	Silent	NA	T34T	0.37
LIHC	chrX	135171105	Missense_Mutation	novel	G23C	0.88
LUAD	chrX	135169665	Silent	NA	L70L	0.21
LUAD	chrX	135158202	Missense_Mutation	NA	E178D	0.11
LUAD	chrX	135171085	Silent	NA	L29L	0.18
LUAD	chrX	135169710	Missense_Mutation	novel	E55K	0.05
LUAD	chrX	135171233	5'UTR	novel		0.11
LUAD	chrX	135169595	Missense_Mutation	novel	K93M	0.24
LUAD	chrX	135169594	Missense_Mutation	novel	K93N	0.14
LUAD	chrX	135160524	Missense_Mutation	novel	A104D	0.65
LUSC	chrX	135169706	Missense_Mutation	rs782056530	S56L	0.79
LUSC	chrX	135169700	Missense_Mutation	novel	Y58C	0.15
LUSC	chrX	135171235	5'UTR	novel		0.27
LUSC	chrX	135160475	Silent	novel	S120S	0.11
LUSC	chrX	135171176	5'UTR	novel		0.1
OV	chrX	135171190	5'UTR	novel		0.21
PAAD	chrX	135171089	Missense_Mutation	novel	G28D	0.21
READ	chrX	135158271	Nonsense_Mutation	novel	Y155*	0.24
SKCM	chrX	135169751	Missense_Mutation	novel	G41E	0.9
SKCM	chrX	135169751	Missense_Mutation	novel	G41E	0.63
SKCM	chrX	135169752	Missense_Mutation	NA	G41R	0.63
SKCM	chrX	135169611	Missense_Mutation	novel	G88R	0.61
SKCM	chrX	135169752	Missense_Mutation	NA	G41R	0.09
SKCM	chrX	135158205	Silent	NA	T177T	0.75
SKCM	chrX	135158270	Missense_Mutation	NA	S156P	0.41
STAD	chrX	135169748	Missense_Mutation	NA	V42A	0.1
STAD	chrX	135169645	Silent	NA	V76V	0.7
STAD	chrX	135160500	Missense_Mutation	NA	R112I	0.88
UCEC	chrX	135171111	Nonsense_Mutation	NA	R21*	0.31
UCEC	chrX	135160534	Missense_Mutation	novel	L101I	0.42
UCEC	chrX	135171228	5'UTR	novel		0.4
UCEC	chrX	135171353	5'UTR	novel		0.4
UCEC	chrX	135158303	Missense_Mutation	novel	P145S	0.41
UCEC	chrX	135158257	Missense_Mutation	novel	G160D	0.4
UCEC	chrX	135169760	Missense_Mutation	NA	T38N	0.29
UCEC	chrX	135158218	Missense_Mutation	novel	R173L	0.17
UCEC	chrX	135160476	Missense_Mutation	novel	S120Y	0.14
UCEC	chrX	135171256	5'UTR	NA		0.3
UCEC	chrX	135160465	Missense_Mutation	novel	D124Y	0.32
UCEC	chrX	135171111	Nonsense_Mutation	NA	R21*	0.47
UCEC	chrX	135158218	Missense_Mutation	novel	R173H	0.48
UCEC	chrX	135160497	Missense_Mutation	novel	V113G	0.13
UCEC	chrX	135171123	Missense_Mutation	rs782523634	D17N	0.47
UCEC	chrX	135160492	Missense_Mutation	novel	I115F	0.21
UCEC	chrX	135160443	Missense_Mutation	novel	S131N	0.37
UCEC	chrX	135169668	Missense_Mutation	novel	P69S	0.37
UCEC	chrX	135160433	Missense_Mutation	novel	F134L	0.09
UCEC	chrX	135171078	Missense_Mutation	novel	G32C	0.43
UCEC	chrX	135169720	Silent	novel	G51G	0.14
UCEC	chrX	135158233	Missense_Mutation	novel	S168F	0.66
UCEC	chrX	135171172	5'UTR	novel		0.26

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	AMP	0.0833	0.24013
KIRC	AMP	0.0303	0.12739
READ	AMP	0.1394	0.14805
TGCT	DEL	0.0667	0.08422
THCA	DEL	0	0.21991
UCS	DEL	0.3036	0.063955

Survival Analysis

Cancer	P-value	Q-value
SARC	0.045	Kaplan-Meier Survival Analysis
SKCM	0.002	Kaplan-Meier Survival Analysis
BRCA	0.043	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742