EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169612 (Gene tree)
Gene ID: 83640
Gene Symbol: RAMAC
Alias: HsT19360|C15orf18|MGC2560|RAM|FAM103A1|RAMMET
Full Name: RNA guanine-7 methyltransferase activating subunit
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 4,855 bases
Position: chr15:82,986,203-82,991,057
Accession: 31022
RBP type: canonical RBP
Summary: (RNA Guanine-7 Methyltransferase Activating Subunit) is a Protein Coding gene. An important paralog of this gene is RAMACL.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000307181	RAM	PF15320.6	1.1e-24	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22099306	RAM/Fam103a1 is required for mRNA cap methylation.	Mol Cell	2011 Nov 18	Gonatopoulos-Pournatzis T	doi: 10.1016/j.molcel.2011.08.041.
29719263	mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription.	Cell Rep	2018 May 1	Varshney D	doi: 10.1016/j.celrep.2018.04.004.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000304191	RAMAC-201	1568	-	ENSP00000307181	118 (aa)	-	Q9BTL3

Gene Model

Click here to download ENSG00000169612's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169612's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169612	RAMAC	51	55.000	ENSAPOG00000004796	RAMAC	100	42.975	Acanthochromis_polyacanthus
ENSG00000169612	RAMAC	100	94.068	ENSAMEG00000000625	-	100	94.068	Ailuropoda_melanoleuca
ENSG00000169612	RAMAC	51	56.667	ENSAOCG00000024054	RAMAC	100	43.802	Amphiprion_ocellaris
ENSG00000169612	RAMAC	51	56.667	ENSAPEG00000024710	RAMAC	100	43.802	Amphiprion_percula
ENSG00000169612	RAMAC	67	53.165	ENSACAG00000013811	-	100	53.165	Anolis_carolinensis
ENSG00000169612	RAMAC	90	42.202	ENSACAG00000023921	-	91	42.202	Anolis_carolinensis
ENSG00000169612	RAMAC	100	96.610	ENSANAG00000026987	-	100	96.610	Aotus_nancymaae
ENSG00000169612	RAMAC	100	88.136	ENSANAG00000022975	-	100	88.136	Aotus_nancymaae
ENSG00000169612	RAMAC	100	92.373	ENSBTAG00000027069	RAMAC	100	92.373	Bos_taurus
ENSG00000169612	RAMAC	98	89.655	ENSCJAG00000038259	-	97	89.655	Callithrix_jacchus
ENSG00000169612	RAMAC	100	95.763	ENSCJAG00000015882	-	100	95.763	Callithrix_jacchus
ENSG00000169612	RAMAC	99	93.162	ENSCAFG00000013181	RAMAC	100	93.162	Canis_familiaris
ENSG00000169612	RAMAC	100	93.220	ENSCAFG00020015938	-	100	93.220	Canis_lupus_dingo
ENSG00000169612	RAMAC	100	93.220	ENSCHIG00000006828	-	100	93.220	Capra_hircus
ENSG00000169612	RAMAC	100	77.119	ENSTSYG00000011955	-	100	77.119	Carlito_syrichta
ENSG00000169612	RAMAC	100	88.983	ENSTSYG00000032997	-	100	88.983	Carlito_syrichta
ENSG00000169612	RAMAC	100	89.831	ENSCAPG00000017693	-	100	89.831	Cavia_aperea
ENSG00000169612	RAMAC	100	89.831	ENSCPOG00000033303	-	100	89.831	Cavia_porcellus
ENSG00000169612	RAMAC	100	96.610	ENSCCAG00000035794	-	100	96.610	Cebus_capucinus
ENSG00000169612	RAMAC	100	98.305	ENSCATG00000033049	-	100	98.305	Cercocebus_atys
ENSG00000169612	RAMAC	100	88.136	ENSCLAG00000007371	-	100	88.136	Chinchilla_lanigera
ENSG00000169612	RAMAC	99	88.889	ENSCHOG00000013717	-	98	88.889	Choloepus_hoffmanni
ENSG00000169612	RAMAC	100	62.500	ENSCPBG00000017593	-	100	62.500	Chrysemys_picta_bellii
ENSG00000169612	RAMAC	100	87.288	ENSCGRG00001021992	-	100	87.288	Cricetulus_griseus_chok1gshd
ENSG00000169612	RAMAC	100	87.288	ENSCGRG00000013886	-	100	87.288	Cricetulus_griseus_crigri
ENSG00000169612	RAMAC	69	52.941	ENSCSEG00000009800	RAMAC	69	52.941	Cynoglossus_semilaevis
ENSG00000169612	RAMAC	85	43.697	ENSCVAG00000011717	RAMAC	98	46.218	Cyprinodon_variegatus
ENSG00000169612	RAMAC	100	82.203	ENSDNOG00000044526	-	100	82.203	Dasypus_novemcinctus
ENSG00000169612	RAMAC	100	82.203	ENSDNOG00000003115	-	100	82.203	Dasypus_novemcinctus
ENSG00000169612	RAMAC	100	78.814	ENSDORG00000012953	-	100	78.814	Dipodomys_ordii
ENSG00000169612	RAMAC	100	75.424	ENSETEG00000006015	-	100	75.424	Echinops_telfairi
ENSG00000169612	RAMAC	100	92.373	ENSEASG00005006977	-	100	92.373	Equus_asinus_asinus
ENSG00000169612	RAMAC	100	92.373	ENSECAG00000023312	RAMAC	100	92.373	Equus_caballus
ENSG00000169612	RAMAC	100	91.525	ENSFCAG00000032519	-	100	91.525	Felis_catus
ENSG00000169612	RAMAC	97	59.649	ENSFALG00000011211	-	94	59.649	Ficedula_albicollis
ENSG00000169612	RAMAC	100	87.288	ENSFDAG00000009442	-	100	87.288	Fukomys_damarensis
ENSG00000169612	RAMAC	75	47.917	ENSFHEG00000006024	RAMAC	77	47.917	Fundulus_heteroclitus
ENSG00000169612	RAMAC	97	57.391	ENSGALG00000006010	RAMAC	97	57.391	Gallus_gallus
ENSG00000169612	RAMAC	100	61.667	ENSGAGG00000021379	-	100	61.667	Gopherus_agassizii
ENSG00000169612	RAMAC	97	78.261	ENSGGOG00000037539	-	94	78.261	Gorilla_gorilla
ENSG00000169612	RAMAC	100	99.153	ENSGGOG00000022754	FAM103A1	100	99.153	Gorilla_gorilla
ENSG00000169612	RAMAC	94	90.991	ENSGGOG00000000654	-	95	90.991	Gorilla_gorilla
ENSG00000169612	RAMAC	70	51.765	ENSHBUG00000002870	RAMAC	69	55.682	Haplochromis_burtoni
ENSG00000169612	RAMAC	100	84.746	ENSHGLG00000020615	-	100	84.746	Heterocephalus_glaber_female
ENSG00000169612	RAMAC	100	85.593	ENSHGLG00000009285	-	100	85.593	Heterocephalus_glaber_female
ENSG00000169612	RAMAC	100	85.593	ENSHGLG00100016903	-	100	85.593	Heterocephalus_glaber_male
ENSG00000169612	RAMAC	100	84.746	ENSHGLG00100020097	-	100	84.746	Heterocephalus_glaber_male
ENSG00000169612	RAMAC	56	50.000	ENSHCOG00000000556	RAMAC	57	50.000	Hippocampus_comes
ENSG00000169612	RAMAC	100	88.235	ENSSTOG00000022253	-	100	88.235	Ictidomys_tridecemlineatus
ENSG00000169612	RAMAC	100	90.678	ENSJJAG00000003727	-	100	90.678	Jaculus_jaculus
ENSG00000169612	RAMAC	93	52.679	ENSLACG00000017822	-	91	52.679	Latimeria_chalumnae
ENSG00000169612	RAMAC	96	49.573	ENSLOCG00000012944	RAMAC	93	48.718	Lepisosteus_oculatus
ENSG00000169612	RAMAC	100	88.136	ENSLAFG00000008134	-	100	88.136	Loxodonta_africana
ENSG00000169612	RAMAC	100	99.153	ENSMFAG00000039932	RAMAC	100	99.153	Macaca_fascicularis
ENSG00000169612	RAMAC	100	99.153	ENSMMUG00000045566	RAMAC	100	99.153	Macaca_mulatta
ENSG00000169612	RAMAC	100	99.153	ENSMLEG00000041885	-	100	99.153	Mandrillus_leucophaeus
ENSG00000169612	RAMAC	100	88.136	ENSMAUG00000016043	-	100	88.136	Mesocricetus_auratus
ENSG00000169612	RAMAC	100	88.983	ENSMICG00000046729	-	100	88.983	Microcebus_murinus
ENSG00000169612	RAMAC	100	87.288	ENSMOCG00000019940	-	100	87.288	Microtus_ochrogaster
ENSG00000169612	RAMAC	56	60.606	ENSMMOG00000018545	RAMAC	52	60.606	Mola_mola
ENSG00000169612	RAMAC	100	83.898	ENSMODG00000023514	-	100	83.898	Monodelphis_domestica
ENSG00000169612	RAMAC	100	84.746	ENSMODG00000019373	-	100	84.746	Monodelphis_domestica
ENSG00000169612	RAMAC	100	77.119	ENSMODG00000019536	-	100	77.119	Monodelphis_domestica
ENSG00000169612	RAMAC	100	83.898	ENSMODG00000025003	-	100	83.898	Monodelphis_domestica
ENSG00000169612	RAMAC	100	86.555	MGP_CAROLIEiJ_G0029925	-	100	86.555	Mus_caroli
ENSG00000169612	RAMAC	54	79.688	MGP_CAROLIEiJ_G0029926	-	97	79.688	Mus_caroli
ENSG00000169612	RAMAC	86	82.524	ENSMUSG00000074826	Gm10767	100	82.524	Mus_musculus
ENSG00000169612	RAMAC	100	86.555	ENSMUSG00000038646	Ramac	100	86.555	Mus_musculus
ENSG00000169612	RAMAC	100	86.555	MGP_PahariEiJ_G0013147	-	100	86.555	Mus_pahari
ENSG00000169612	RAMAC	59	75.676	MGP_PahariEiJ_G0013148	-	96	75.676	Mus_pahari
ENSG00000169612	RAMAC	86	83.495	MGP_SPRETEiJ_G0019535	Gm10767	100	83.495	Mus_spretus
ENSG00000169612	RAMAC	67	83.544	MGP_SPRETEiJ_G0019537	-	79	83.544	Mus_spretus
ENSG00000169612	RAMAC	100	86.555	MGP_SPRETEiJ_G0031028	Ramac	100	86.555	Mus_spretus
ENSG00000169612	RAMAC	100	86.441	ENSMLUG00000008298	-	100	86.441	Myotis_lucifugus
ENSG00000169612	RAMAC	100	88.136	ENSNGAG00000017332	-	99	88.136	Nannospalax_galili
ENSG00000169612	RAMAC	94	79.279	ENSNLEG00000034853	-	94	79.279	Nomascus_leucogenys
ENSG00000169612	RAMAC	100	99.153	ENSNLEG00000010942	-	100	99.153	Nomascus_leucogenys
ENSG00000169612	RAMAC	100	84.746	ENSODEG00000015254	-	100	84.746	Octodon_degus
ENSG00000169612	RAMAC	100	74.576	ENSOANG00000004275	-	100	74.576	Ornithorhynchus_anatinus
ENSG00000169612	RAMAC	85	43.689	ENSOMEG00000011658	RAMAC	97	43.689	Oryzias_melastigma
ENSG00000169612	RAMAC	100	84.746	ENSOGAG00000008039	-	100	84.746	Otolemur_garnettii
ENSG00000169612	RAMAC	100	93.220	ENSOARG00000013962	-	100	93.220	Ovis_aries
ENSG00000169612	RAMAC	100	99.153	ENSPPAG00000042316	-	100	99.153	Pan_paniscus
ENSG00000169612	RAMAC	100	70.339	ENSPPAG00000039905	-	100	70.339	Pan_paniscus
ENSG00000169612	RAMAC	100	91.525	ENSPPRG00000011086	-	100	91.525	Panthera_pardus
ENSG00000169612	RAMAC	100	91.525	ENSPTIG00000009107	-	100	91.525	Panthera_tigris_altaica
ENSG00000169612	RAMAC	100	99.153	ENSPTRG00000007387	RAMAC	100	99.153	Pan_troglodytes
ENSG00000169612	RAMAC	100	99.153	ENSPANG00000020645	-	100	99.153	Papio_anubis
ENSG00000169612	RAMAC	97	45.378	ENSPKIG00000019767	RAMAC	68	45.378	Paramormyrops_kingsleyae
ENSG00000169612	RAMAC	100	63.333	ENSPSIG00000006833	-	100	63.333	Pelodiscus_sinensis
ENSG00000169612	RAMAC	92	40.426	ENSPMGG00000000787	RAMAC	64	49.000	Periophthalmus_magnuspinnatus
ENSG00000169612	RAMAC	100	84.746	ENSPCIG00000008378	-	100	84.746	Phascolarctos_cinereus
ENSG00000169612	RAMAC	61	51.389	ENSPFOG00000017361	RAMAC	74	47.872	Poecilia_formosa
ENSG00000169612	RAMAC	61	51.389	ENSPLAG00000019830	RAMAC	78	47.368	Poecilia_latipinna
ENSG00000169612	RAMAC	61	51.389	ENSPMEG00000024042	RAMAC	78	47.368	Poecilia_mexicana
ENSG00000169612	RAMAC	100	99.153	ENSPPYG00000006736	RAMAC	100	99.153	Pongo_abelii
ENSG00000169612	RAMAC	100	89.831	ENSPCAG00000016435	-	100	89.831	Procavia_capensis
ENSG00000169612	RAMAC	100	88.136	ENSPCOG00000019685	-	100	88.136	Propithecus_coquereli
ENSG00000169612	RAMAC	100	94.068	ENSPVAG00000009382	-	100	94.068	Pteropus_vampyrus
ENSG00000169612	RAMAC	100	84.034	ENSRNOG00000019426	Ramac	100	84.034	Rattus_norvegicus
ENSG00000169612	RAMAC	100	98.305	ENSRBIG00000039782	-	100	98.305	Rhinopithecus_bieti
ENSG00000169612	RAMAC	100	98.305	ENSRROG00000032118	-	100	98.305	Rhinopithecus_roxellana
ENSG00000169612	RAMAC	100	79.661	ENSSBOG00000025722	-	100	79.661	Saimiri_boliviensis_boliviensis
ENSG00000169612	RAMAC	100	93.220	ENSSBOG00000031767	-	100	93.220	Saimiri_boliviensis_boliviensis
ENSG00000169612	RAMAC	99	84.615	ENSSHAG00000017873	-	99	84.615	Sarcophilus_harrisii
ENSG00000169612	RAMAC	92	45.536	ENSSFOG00015016816	RAMAC	76	45.536	Scleropages_formosus
ENSG00000169612	RAMAC	100	77.119	ENSSARG00000006307	-	100	77.119	Sorex_araneus
ENSG00000169612	RAMAC	81	62.500	ENSSPUG00000010499	-	100	61.475	Sphenodon_punctatus
ENSG00000169612	RAMAC	100	46.212	ENSSPAG00000010519	RAMAC	100	48.855	Stegastes_partitus
ENSG00000169612	RAMAC	100	89.831	ENSSSCG00000038630	-	100	89.831	Sus_scrofa
ENSG00000169612	RAMAC	51	56.667	ENSTNIG00000009492	RAMAC	59	46.465	Tetraodon_nigroviridis
ENSG00000169612	RAMAC	100	82.203	ENSTBEG00000014299	-	100	82.203	Tupaia_belangeri
ENSG00000169612	RAMAC	100	94.068	ENSTTRG00000004932	FAM103A1	100	94.068	Tursiops_truncatus
ENSG00000169612	RAMAC	100	94.915	ENSUAMG00000006286	-	100	94.915	Ursus_americanus
ENSG00000169612	RAMAC	100	94.915	ENSUMAG00000010167	-	100	94.915	Ursus_maritimus
ENSG00000169612	RAMAC	100	73.729	ENSVPAG00000009431	-	100	73.729	Vicugna_pacos
ENSG00000169612	RAMAC	100	94.068	ENSVVUG00000005104	-	100	94.068	Vulpes_vulpes
ENSG00000169612	RAMAC	93	52.252	ENSXETG00000030369	rammet	91	52.252	Xenopus_tropicalis
ENSG00000169612	RAMAC	75	49.474	ENSXMAG00000015208	RAMAC	78	49.474	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003723	RNA binding	22099306.	IDA	Function
GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	27422871.	IDA	Function
GO:0005515	protein binding	16189514.22099306.25416956.27422871.30021884.	IPI	Function
GO:0005634	nucleus	22099306.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005845	mRNA cap binding complex	22099306.	IDA	Component
GO:0006370	7-methylguanosine mRNA capping	22099306.	IDA	Process
GO:0031533	mRNA cap methyltransferase complex	27422871.	IDA	Component
GO:0032259	methylation	22099306.	IMP	Process
GO:0036031	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	22099306.	IDA	Process
GO:0106005	RNA 5'-cap (guanine-N7)-methylation	-	IEA	Process