EuRBPDB

Description

Ensembl ID: ENSG00000169641 (Gene tree)
Gene ID: 7798
Gene Symbol: LUZP1
Alias: LUZP
Full Name: leucine zipper protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 93,786 bases
Position: chr1:23,084,023-23,177,808
Accession: 14985
RBP type: non-canonical RBP
Summary: This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000475164	LUZP1-205	613	-	ENSP00000429657	35 (aa)	-	E5RHU7
ENST00000418342	LUZP1-203	8421	-	ENSP00000393460	1076 (aa)	-	Q86V48
ENST00000302291	LUZP1-201	8898	XM_011542090	ENSP00000303758	1076 (aa)	XP_011540392	Q86V48
ENST00000471849	LUZP1-204	1190	-	ENSP00000428061	273 (aa)	-	E5RFK8
ENST00000314174	LUZP1-202	3715	-	ENSP00000313705	1026 (aa)	-	Q86V48

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000169641	Myocardial Infarction	3.3096853E-004	-
ENSG00000169641	Platelet Function Tests	1.7053000E-005	-
ENSG00000169641	Platelet Function Tests	1.2534000E-005	-
ENSG00000169641	coenzyme Q10	4E-6	27149984
ENSG00000169641	Body Height	2E-20	25282103

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000169641	rs9426691	1	23158411	G	Coenzyme Q10 levels	27149984	[0.019-0.046] unit decrease	0.032	EFO_0007836
ENSG00000169641	rs10799792	1	23119948	T	Global electrical heterogeneity phenotypes	29622589	[0.055-0.105] unit increase	0.08	EFO_0004327

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169641	LUZP1	100	90.146	ENSMUSG00000001089	Luzp1	100	87.879	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003281	ventricular septum development	-	IEA	Process
GO:0005634	nucleus	-	IEA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0021503	neural fold bending	21873635.	IBA	Process
GO:0060840	artery development	-	IEA	Process
GO:0070062	extracellular exosome	18570454.	HDA	Component