EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169718 (Gene tree)
Gene ID: 64118
Gene Symbol: DUS1L
Alias: PP3111|DUS1
Full Name: dihydrouridine synthase 1 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 8,382 bases
Position: chr17:82,057,506-82,065,887
Accession: 30086
RBP type: canonical RBP
Summary: (Dihydrouridine Synthase 1 Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include flavin adenine dinucleotide binding and tRNA dihydrouridine synthase activity. An important paralog of this gene is DUS4L.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000463509	Dus	PF01207.17	1e-73	1	1
ENSP00000303515	Dus	PF01207.17	2.3e-73	1	1
ENSP00000346280	Dus	PF01207.17	2.3e-73	1	1
ENSP00000463962	Dus	PF01207.17	7.5e-67	1	1
ENSP00000463180	Dus	PF01207.17	2.8e-61	1	2
ENSP00000463180	Dus	PF01207.17	2.8e-61	2	2
ENSP00000445110	Dus	PF01207.17	2e-35	1	1
ENSP00000463797	Dus	PF01207.17	1.2e-28	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000578846	DUS1L-210	4456	-	-	- (aa)	-	-
ENST00000542088	DUS1L-204	1040	-	ENSP00000438718	239 (aa)	-	F5H0Q0
ENST00000354321	DUS1L-202	2151	-	ENSP00000346280	473 (aa)	-	Q6P1R4
ENST00000582529	DUS1L-215	1212	-	ENSP00000463509	309 (aa)	-	J3QLE4
ENST00000538833	DUS1L-203	1250	-	ENSP00000445110	298 (aa)	-	H0YGW8
ENST00000584871	DUS1L-216	676	-	-	- (aa)	-	-
ENST00000579854	DUS1L-212	657	-	-	- (aa)	-	-
ENST00000582407	DUS1L-214	714	-	-	- (aa)	-	-
ENST00000577907	DUS1L-206	648	-	ENSP00000463797	152 (aa)	-	J3QQL9
ENST00000580731	DUS1L-213	725	-	ENSP00000462526	191 (aa)	-	J3KSK2
ENST00000578907	DUS1L-211	1084	-	ENSP00000463962	301 (aa)	-	J3QQZ0
ENST00000578176	DUS1L-207	937	-	ENSP00000463180	247 (aa)	-	J3QKP9
ENST00000578428	DUS1L-209	688	-	-	- (aa)	-	-
ENST00000577574	DUS1L-205	473	-	ENSP00000462812	152 (aa)	-	J3KT57
ENST00000306796	DUS1L-201	2068	XM_005256393	ENSP00000303515	473 (aa)	XP_005256450	Q6P1R4
ENST00000578264	DUS1L-208	1071	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000169718's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169718's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000169718	DUS1L	91	36.179	ENSG00000105865	DUS4L	76	44.565

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169718	DUS1L	93	69.792	ENSAPOG00000007899	dus1l	91	59.302	Acanthochromis_polyacanthus
ENSG00000169718	DUS1L	54	84.146	ENSAPOG00000020141	-	86	87.342	Acanthochromis_polyacanthus
ENSG00000169718	DUS1L	100	96.117	ENSAMEG00000017313	DUS1L	100	91.579	Ailuropoda_melanoleuca
ENSG00000169718	DUS1L	100	83.226	ENSACIG00000013505	dus1l	89	73.673	Amphilophus_citrinellus
ENSG00000169718	DUS1L	100	83.871	ENSAOCG00000023872	dus1l	92	76.201	Amphiprion_ocellaris
ENSG00000169718	DUS1L	100	83.871	ENSAPEG00000021394	dus1l	92	76.201	Amphiprion_percula
ENSG00000169718	DUS1L	100	83.871	ENSATEG00000009144	dus1l	95	76.222	Anabas_testudineus
ENSG00000169718	DUS1L	100	85.942	ENSAPLG00000001965	DUS1L	99	79.132	Anas_platyrhynchos
ENSG00000169718	DUS1L	100	85.437	ENSACAG00000009945	DUS1L	99	80.260	Anolis_carolinensis
ENSG00000169718	DUS1L	100	98.058	ENSANAG00000030037	DUS1L	100	95.983	Aotus_nancymaae
ENSG00000169718	DUS1L	100	83.226	ENSACLG00000004307	dus1l	94	75.217	Astatotilapia_calliptera
ENSG00000169718	DUS1L	100	80.323	ENSAMXG00000031331	dus1l	93	74.107	Astyanax_mexicanus
ENSG00000169718	DUS1L	100	96.117	ENSBTAG00000047760	DUS1L	100	92.211	Bos_taurus
ENSG00000169718	DUS1L	98	46.970	WBGene00009452	F36A2.2	87	39.316	Caenorhabditis_elegans
ENSG00000169718	DUS1L	100	98.382	ENSCJAG00000018104	-	100	96.203	Callithrix_jacchus
ENSG00000169718	DUS1L	96	92.593	ENSCJAG00000011502	-	98	90.870	Callithrix_jacchus
ENSG00000169718	DUS1L	100	96.440	ENSCAFG00000005952	DUS1L	100	93.053	Canis_familiaris
ENSG00000169718	DUS1L	100	96.440	ENSCAFG00020010251	DUS1L	100	94.395	Canis_lupus_dingo
ENSG00000169718	DUS1L	100	96.440	ENSCHIG00000019382	DUS1L	91	92.918	Capra_hircus
ENSG00000169718	DUS1L	100	97.411	ENSTSYG00000010792	DUS1L	100	94.937	Carlito_syrichta
ENSG00000169718	DUS1L	90	76.259	ENSCAPG00000010515	DUS1L	99	76.791	Cavia_aperea
ENSG00000169718	DUS1L	100	95.469	ENSCPOG00000030880	DUS1L	100	89.684	Cavia_porcellus
ENSG00000169718	DUS1L	100	98.382	ENSCCAG00000032592	DUS1L	100	96.195	Cebus_capucinus
ENSG00000169718	DUS1L	100	99.353	ENSCATG00000039553	DUS1L	100	98.943	Cercocebus_atys
ENSG00000169718	DUS1L	100	95.469	ENSCLAG00000014832	DUS1L	100	91.158	Chinchilla_lanigera
ENSG00000169718	DUS1L	100	99.366	ENSCSAG00000002157	DUS1L	100	99.366	Chlorocebus_sabaeus
ENSG00000169718	DUS1L	100	87.702	ENSCPBG00000011543	DUS1L	92	82.863	Chrysemys_picta_bellii
ENSG00000169718	DUS1L	97	54.088	ENSCING00000022313	-	99	60.417	Ciona_intestinalis
ENSG00000169718	DUS1L	99	62.214	ENSCING00000007479	-	99	52.434	Ciona_intestinalis
ENSG00000169718	DUS1L	99	64.596	ENSCSAVG00000001475	-	99	53.670	Ciona_savignyi
ENSG00000169718	DUS1L	99	57.655	ENSCSAVG00000000712	-	99	52.394	Ciona_savignyi
ENSG00000169718	DUS1L	100	99.676	ENSCANG00000040274	DUS1L	100	98.943	Colobus_angolensis_palliatus
ENSG00000169718	DUS1L	100	94.822	ENSCGRG00001021324	Dus1l	100	89.834	Cricetulus_griseus_chok1gshd
ENSG00000169718	DUS1L	100	94.822	ENSCGRG00000015480	Dus1l	100	91.158	Cricetulus_griseus_crigri
ENSG00000169718	DUS1L	100	82.258	ENSCSEG00000013675	dus1l	56	74.818	Cynoglossus_semilaevis
ENSG00000169718	DUS1L	100	84.839	ENSCVAG00000010146	dus1l	94	79.882	Cyprinodon_variegatus
ENSG00000169718	DUS1L	100	81.935	ENSDARG00000089260	dus1l	90	75.281	Danio_rerio
ENSG00000169718	DUS1L	100	87.730	ENSDNOG00000040876	-	97	91.453	Dasypus_novemcinctus
ENSG00000169718	DUS1L	90	81.181	ENSDORG00000028758	Dus1l	100	83.586	Dipodomys_ordii
ENSG00000169718	DUS1L	99	60.687	FBgn0031238	CG3645	92	50.964	Drosophila_melanogaster
ENSG00000169718	DUS1L	100	90.939	ENSETEG00000013903	DUS1L	100	84.696	Echinops_telfairi
ENSG00000169718	DUS1L	98	60.396	ENSEBUG00000001370	dus1l	88	58.383	Eptatretus_burgeri
ENSG00000169718	DUS1L	100	97.087	ENSEASG00005005886	DUS1L	100	93.684	Equus_asinus_asinus
ENSG00000169718	DUS1L	100	97.411	ENSECAG00000017904	DUS1L	100	93.111	Equus_caballus
ENSG00000169718	DUS1L	78	77.637	ENSEEUG00000014275	-	100	76.952	Erinaceus_europaeus
ENSG00000169718	DUS1L	99	82.746	ENSELUG00000011137	dus1l	97	73.737	Esox_lucius
ENSG00000169718	DUS1L	100	96.117	ENSFCAG00000011683	DUS1L	91	93.318	Felis_catus
ENSG00000169718	DUS1L	100	87.702	ENSFALG00000011707	DUS1L	96	81.624	Ficedula_albicollis
ENSG00000169718	DUS1L	100	94.175	ENSFDAG00000007140	DUS1L	100	89.684	Fukomys_damarensis
ENSG00000169718	DUS1L	100	83.871	ENSFHEG00000002025	dus1l	91	77.111	Fundulus_heteroclitus
ENSG00000169718	DUS1L	100	80.323	ENSGMOG00000008030	dus1l	100	74.032	Gadus_morhua
ENSG00000169718	DUS1L	100	88.026	ENSGALG00000034115	DUS1L	97	81.356	Gallus_gallus
ENSG00000169718	DUS1L	100	84.194	ENSGAFG00000006321	dus1l	93	76.253	Gambusia_affinis
ENSG00000169718	DUS1L	100	83.548	ENSGACG00000005403	dus1l	100	76.471	Gasterosteus_aculeatus
ENSG00000169718	DUS1L	100	87.379	ENSGAGG00000016657	DUS1L	100	79.339	Gopherus_agassizii
ENSG00000169718	DUS1L	100	100.000	ENSGGOG00000011636	DUS1L	100	99.154	Gorilla_gorilla
ENSG00000169718	DUS1L	100	81.935	ENSHBUG00000009512	dus1l	94	74.348	Haplochromis_burtoni
ENSG00000169718	DUS1L	100	95.146	ENSHGLG00000010316	DUS1L	100	90.737	Heterocephalus_glaber_female
ENSG00000169718	DUS1L	100	95.146	ENSHGLG00100009264	DUS1L	100	90.737	Heterocephalus_glaber_male
ENSG00000169718	DUS1L	100	80.323	ENSHCOG00000007433	dus1l	90	73.214	Hippocampus_comes
ENSG00000169718	DUS1L	100	82.209	ENSIPUG00000014839	dus1l	99	74.393	Ictalurus_punctatus
ENSG00000169718	DUS1L	100	96.764	ENSSTOG00000003787	DUS1L	100	91.789	Ictidomys_tridecemlineatus
ENSG00000169718	DUS1L	100	94.822	ENSJJAG00000020218	Dus1l	100	90.526	Jaculus_jaculus
ENSG00000169718	DUS1L	100	82.258	ENSKMAG00000014147	dus1l	93	74.561	Kryptolebias_marmoratus
ENSG00000169718	DUS1L	100	83.871	ENSLBEG00000021685	dus1l	94	76.087	Labrus_bergylta
ENSG00000169718	DUS1L	100	83.819	ENSLACG00000011348	DUS1L	97	77.039	Latimeria_chalumnae
ENSG00000169718	DUS1L	100	85.113	ENSLOCG00000012342	dus1l	94	78.478	Lepisosteus_oculatus
ENSG00000169718	DUS1L	100	93.528	ENSLAFG00000003230	DUS1L	100	87.629	Loxodonta_africana
ENSG00000169718	DUS1L	100	99.353	ENSMFAG00000001187	DUS1L	100	99.154	Macaca_fascicularis
ENSG00000169718	DUS1L	100	99.353	ENSMMUG00000012803	DUS1L	100	99.154	Macaca_mulatta
ENSG00000169718	DUS1L	100	99.353	ENSMNEG00000010573	DUS1L	100	99.154	Macaca_nemestrina
ENSG00000169718	DUS1L	100	93.252	ENSMLEG00000035767	DUS1L	97	99.149	Mandrillus_leucophaeus
ENSG00000169718	DUS1L	100	82.581	ENSMAMG00000001703	dus1l	96	73.941	Mastacembelus_armatus
ENSG00000169718	DUS1L	100	83.226	ENSMZEG00005023163	dus1l	94	75.217	Maylandia_zebra
ENSG00000169718	DUS1L	99	83.987	ENSMGAG00000005146	DUS1L	96	80.000	Meleagris_gallopavo
ENSG00000169718	DUS1L	100	94.498	ENSMAUG00000015152	Dus1l	100	90.947	Mesocricetus_auratus
ENSG00000169718	DUS1L	100	96.764	ENSMICG00000010159	DUS1L	100	93.038	Microcebus_murinus
ENSG00000169718	DUS1L	100	93.528	ENSMOCG00000018377	Dus1l	100	90.737	Microtus_ochrogaster
ENSG00000169718	DUS1L	100	83.548	ENSMMOG00000005580	dus1l	98	72.949	Mola_mola
ENSG00000169718	DUS1L	100	90.615	ENSMODG00000003351	DUS1L	99	84.167	Monodelphis_domestica
ENSG00000169718	DUS1L	100	82.581	ENSMALG00000002013	dus1l	95	74.200	Monopterus_albus
ENSG00000169718	DUS1L	100	97.368	MGP_CAROLIEiJ_G0017546	Dus1l	100	97.590	Mus_caroli
ENSG00000169718	DUS1L	100	97.368	ENSMUSG00000025155	Dus1l	100	97.590	Mus_musculus
ENSG00000169718	DUS1L	100	98.026	MGP_PahariEiJ_G0018673	Dus1l	100	98.193	Mus_pahari
ENSG00000169718	DUS1L	100	97.368	MGP_SPRETEiJ_G0018390	Dus1l	100	97.590	Mus_spretus
ENSG00000169718	DUS1L	90	92.164	ENSMLUG00000016577	DUS1L	100	90.524	Myotis_lucifugus
ENSG00000169718	DUS1L	100	94.822	ENSNGAG00000018676	Dus1l	100	88.613	Nannospalax_galili
ENSG00000169718	DUS1L	83	84.762	ENSNBRG00000009083	dus1l	93	84.762	Neolamprologus_brichardi
ENSG00000169718	DUS1L	69	81.897	ENSNBRG00000000207	-	95	90.517	Neolamprologus_brichardi
ENSG00000169718	DUS1L	100	92.389	ENSNLEG00000014021	DUS1L	100	92.389	Nomascus_leucogenys
ENSG00000169718	DUS1L	100	87.730	ENSMEUG00000004630	DUS1L	99	79.958	Notamacropus_eugenii
ENSG00000169718	DUS1L	78	84.615	ENSOPRG00000012308	DUS1L	78	82.295	Ochotona_princeps
ENSG00000169718	DUS1L	100	94.822	ENSODEG00000007777	DUS1L	100	87.683	Octodon_degus
ENSG00000169718	DUS1L	100	84.194	ENSONIG00000006234	dus1l	96	75.217	Oreochromis_niloticus
ENSG00000169718	DUS1L	100	84.516	ENSORLG00000017223	dus1l	92	75.192	Oryzias_latipes
ENSG00000169718	DUS1L	100	81.595	ENSORLG00020018056	dus1l	79	87.069	Oryzias_latipes_hni
ENSG00000169718	DUS1L	100	84.839	ENSORLG00015010473	dus1l	87	77.333	Oryzias_latipes_hsok
ENSG00000169718	DUS1L	100	83.226	ENSOMEG00000012607	dus1l	92	74.565	Oryzias_melastigma
ENSG00000169718	DUS1L	100	96.764	ENSOGAG00000005494	DUS1L	99	92.949	Otolemur_garnettii
ENSG00000169718	DUS1L	100	96.764	ENSOARG00000017277	DUS1L	100	93.053	Ovis_aries
ENSG00000169718	DUS1L	100	100.000	ENSPPAG00000027029	DUS1L	100	99.789	Pan_paniscus
ENSG00000169718	DUS1L	100	95.469	ENSPPRG00000012135	DUS1L	100	89.263	Panthera_pardus
ENSG00000169718	DUS1L	92	88.742	ENSPTIG00000021001	DUS1L	98	77.011	Panthera_tigris_altaica
ENSG00000169718	DUS1L	100	93.252	ENSPTRG00000009790	DUS1L	87	98.515	Pan_troglodytes
ENSG00000169718	DUS1L	100	99.676	ENSPTRG00000039913	-	100	99.577	Pan_troglodytes
ENSG00000169718	DUS1L	100	99.353	ENSPANG00000018945	DUS1L	100	99.154	Papio_anubis
ENSG00000169718	DUS1L	100	81.230	ENSPKIG00000009901	dus1l	96	74.312	Paramormyrops_kingsleyae
ENSG00000169718	DUS1L	100	83.819	ENSPSIG00000009963	DUS1L	98	79.828	Pelodiscus_sinensis
ENSG00000169718	DUS1L	100	84.839	ENSPMGG00000005015	dus1l	91	77.193	Periophthalmus_magnuspinnatus
ENSG00000169718	DUS1L	100	95.146	ENSPEMG00000011610	Dus1l	100	91.368	Peromyscus_maniculatus_bairdii
ENSG00000169718	DUS1L	100	90.615	ENSPCIG00000023887	DUS1L	99	84.167	Phascolarctos_cinereus
ENSG00000169718	DUS1L	100	84.839	ENSPFOG00000019577	dus1l	93	76.471	Poecilia_formosa
ENSG00000169718	DUS1L	100	84.839	ENSPLAG00000021350	dus1l	93	76.471	Poecilia_latipinna
ENSG00000169718	DUS1L	100	84.516	ENSPMEG00000000698	dus1l	93	76.253	Poecilia_mexicana
ENSG00000169718	DUS1L	100	84.516	ENSPREG00000007263	dus1l	93	76.688	Poecilia_reticulata
ENSG00000169718	DUS1L	100	99.676	ENSPPYG00000008767	DUS1L	100	99.366	Pongo_abelii
ENSG00000169718	DUS1L	100	96.117	ENSPCOG00000021919	DUS1L	100	92.227	Propithecus_coquereli
ENSG00000169718	DUS1L	99	93.831	ENSPVAG00000002524	DUS1L	100	89.662	Pteropus_vampyrus
ENSG00000169718	DUS1L	100	83.226	ENSPNYG00000022627	dus1l	91	74.568	Pundamilia_nyererei
ENSG00000169718	DUS1L	100	81.290	ENSPNAG00000014263	dus1l	93	73.884	Pygocentrus_nattereri
ENSG00000169718	DUS1L	100	94.498	ENSRNOG00000047905	Dus1l	99	89.908	Rattus_norvegicus
ENSG00000169718	DUS1L	100	99.676	ENSRBIG00000034870	DUS1L	100	98.943	Rhinopithecus_bieti
ENSG00000169718	DUS1L	100	99.676	ENSRROG00000036079	DUS1L	100	98.732	Rhinopithecus_roxellana
ENSG00000169718	DUS1L	100	52.439	YML080W	-	87	44.086	Saccharomyces_cerevisiae
ENSG00000169718	DUS1L	100	97.411	ENSSBOG00000021620	DUS1L	100	96.195	Saimiri_boliviensis_boliviensis
ENSG00000169718	DUS1L	100	90.291	ENSSHAG00000005402	DUS1L	99	84.200	Sarcophilus_harrisii
ENSG00000169718	DUS1L	100	82.201	ENSSFOG00015023351	dus1l	99	72.939	Scleropages_formosus
ENSG00000169718	DUS1L	100	82.581	ENSSMAG00000016562	dus1l	96	73.093	Scophthalmus_maximus
ENSG00000169718	DUS1L	100	82.258	ENSSDUG00000023398	dus1l	92	75.000	Seriola_dumerili
ENSG00000169718	DUS1L	100	82.258	ENSSLDG00000011548	dus1l	92	75.000	Seriola_lalandi_dorsalis
ENSG00000169718	DUS1L	100	86.731	ENSSPUG00000006796	DUS1L	90	81.385	Sphenodon_punctatus
ENSG00000169718	DUS1L	100	71.383	ENSSPAG00000008618	dus1l	95	66.593	Stegastes_partitus
ENSG00000169718	DUS1L	100	96.440	ENSSSCG00000040352	DUS1L	100	91.158	Sus_scrofa
ENSG00000169718	DUS1L	100	86.731	ENSTGUG00000003700	DUS1L	97	80.983	Taeniopygia_guttata
ENSG00000169718	DUS1L	100	79.935	ENSTRUG00000011243	dus1l	95	69.181	Takifugu_rubripes
ENSG00000169718	DUS1L	100	83.871	ENSTNIG00000013994	dus1l	99	76.682	Tetraodon_nigroviridis
ENSG00000169718	DUS1L	100	96.440	ENSTTRG00000001583	DUS1L	100	92.421	Tursiops_truncatus
ENSG00000169718	DUS1L	100	96.117	ENSUAMG00000022847	DUS1L	100	91.789	Ursus_americanus
ENSG00000169718	DUS1L	99	94.788	ENSUMAG00000016749	DUS1L	100	85.177	Ursus_maritimus
ENSG00000169718	DUS1L	100	96.764	ENSVVUG00000001205	DUS1L	87	94.802	Vulpes_vulpes
ENSG00000169718	DUS1L	98	87.459	ENSXETG00000019654	dus1l	95	81.306	Xenopus_tropicalis
ENSG00000169718	DUS1L	100	84.194	ENSXCOG00000009784	dus1l	95	75.381	Xiphophorus_couchianus
ENSG00000169718	DUS1L	100	84.194	ENSXMAG00000005147	dus1l	93	76.471	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002943	tRNA dihydrouridine synthesis	-	IEA	Process
GO:0017150	tRNA dihydrouridine synthase activity	21873635.	IBA	Function
GO:0050660	flavin adenine dinucleotide binding	-	IEA	Function
GO:0055114	oxidation-reduction process	-	IEA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr17	82061976	Missense_Mutation	rs138482688	T173M	0.94
BLCA	chr17	82061721	Splice_Region	novel	R198R	0.12
BLCA	chr17	82062870	Silent	rs114799231	A167A	0.14
BLCA	chr17	82061963	Silent	novel	R177R	0.12
BLCA	chr17	82065025	Missense_Mutation	novel	R12H	0.06
BLCA	chr17	82058041	3'UTR	novel		0.1
BLCA	chr17	82060901	Silent	novel	I301I	0.1
BLCA	chr17	82061345	Silent	novel	L236L	0.33
BLCA	chr17	82060020	Missense_Mutation	NA	E366K	0.18
BLCA	chr17	82058371	Missense_Mutation	novel	R418G	0.42
BLCA	chr17	82061951	Missense_Mutation	novel	Q181H	0.12
BLCA	chr17	82061354	Splice_Site	NA	X233_splice	0.16
BLCA	chr17	82059954	Missense_Mutation	novel	L388V	0.22
BRCA	chr17	82062903	Missense_Mutation	novel	K156N	0.12
BRCA	chr17	82061722	Splice_Site	NA	X198_splice	0.2
BRCA	chr17	82060945	Missense_Mutation	NA	E287K	0.38
BRCA	chr17	82060053	Missense_Mutation	novel	K355E	0.13
CESC	chr17	82064171	Missense_Mutation	novel	A101T	0.26	Dus
CESC	chr17	82064216	Missense_Mutation	NA	E86K	0.11	Dus
CESC	chr17	82064877	Silent	novel	R61R	0.1
COAD	chr17	82060778	In_Frame_Del	NA	E315del	0.28
COAD	chr17	82062900	Silent	rs771000522	T157T	0.31
COAD	chr17	82064928	Nonsense_Mutation	NA	C44*	0.28	Dus
COAD	chr17	82061332	Missense_Mutation	novel	A240V	0.28
COAD	chr17	82062937	Missense_Mutation	rs751958468	T145M	0.21
ESCA	chr17	82058068	3'UTR	rs754318992		0.46
GBM	chr17	82064888	Missense_Mutation	rs371267525	A58T	0.37	Dus
GBM	chr17	82059964	Silent	rs779213694	F384F	0.19
GBM	chr17	82062925	Missense_Mutation	rs760210278	R149H	0.27
HNSC	chr17	82061688	Silent	novel	G209G	0.21
HNSC	chr17	82063492	Missense_Mutation	novel	E125Q	0.19	Dus
HNSC	chr17	82061274	Silent	rs750909173	I259I	0.26
LGG	chr17	82058050	3'UTR	novel		0.29
LIHC	chr17	82060064	Missense_Mutation	NA	G351V	0.17
LIHC	chr17	82061689	Missense_Mutation	NA	G209E	0.38
LUSC	chr17	82065030	Missense_Mutation	novel	W10C	0.35
LUSC	chr17	82061324	Missense_Mutation	NA	E243K	0.11
OV	chr17	82058209	In_Frame_Ins	novel	W443delinsSG	0.43
OV	chr17	82062970	Missense_Mutation	NA	L134S	1	Dus
PAAD	chr17	82061941	Missense_Mutation	novel	L185M	0.14
PAAD	chr17	82063505	Silent	novel	A120A	0.08
PRAD	chr17	82058154	Silent	NA	P461P	0.23
PRAD	chr17	82061965	Missense_Mutation	rs768534602	R177C	0.41
PRAD	chr17	82058350	Missense_Mutation	novel	D425Y	0.14
READ	chr17	82060006	Silent	NA	K370K	0.19
READ	chr17	82061621	Missense_Mutation	rs114350519	A232T	0.17
SKCM	chr17	82058143	Missense_Mutation	novel	S465F	0.23
SKCM	chr17	82060921	Missense_Mutation	novel	V295M	0.25
SKCM	chr17	82064186	In_Frame_Del	novel	L94_A95del	0.35	Dus
SKCM	chr17	82060882	Silent	NA	L308L	0.14
SKCM	chr17	82062926	Missense_Mutation	rs532728681	R149C	0.2
SKCM	chr17	82061262	Silent	rs369444572	H263H	0.47
SKCM	chr17	82061263	Missense_Mutation	novel	H263L	0.48
SKCM	chr17	82061651	Missense_Mutation	rs766051331	R222W	0.4
SKCM	chr17	82064841	Silent	NA	D73D	0.4
STAD	chr17	82061965	Missense_Mutation	rs768534602	R177C	0.2
STAD	chr17	82063508	Silent	rs368906150	G119G	0.21
STAD	chr17	82060730	Silent	rs780520593	H331H	0.55
STAD	chr17	82058051	3'UTR	novel		0.16
STAD	chr17	82062908	Missense_Mutation	novel	D155H	0.11
STAD	chr17	82061232	Silent	NA	H273H	0.3
STAD	chr17	82058370	Missense_Mutation	rs376659580	R418Q	0.05
STAD	chr17	82061951	Silent	NA	Q181Q	0.78
STAD	chr17	82060062	Missense_Mutation	NA	A352T	0.24
STAD	chr17	82065093	Intron	novel		0.19
STAD	chr17	82061968	Missense_Mutation	NA	G176R	0.08
STAD	chr17	82060049	Missense_Mutation	rs138475537	R356Q	0.16
STAD	chr17	82061901	Missense_Mutation	rs778657338	R198Q	0.2
STAD	chr17	82060024	Silent	rs761406134	G364G	0.28
UCEC	chr17	82064214	Missense_Mutation	NA	E86D	0.41	Dus
UCEC	chr17	82059994	Missense_Mutation	NA	K374N	0.33
UCEC	chr17	82065050	Missense_Mutation	novel	L4M	0.38
UCEC	chr17	82065000	Silent	rs772411249	V20V	0.33
UCEC	chr17	82058388	Missense_Mutation	novel	R412H	0.3
UCEC	chr17	82061314	Missense_Mutation	novel	S246N	0.22
UCEC	chr17	82061959	Missense_Mutation	novel	K179E	0.13
UCEC	chr17	82061975	Silent	novel	T173T	0.35
UCEC	chr17	82061270	Missense_Mutation	NA	R261W	0.24
UCEC	chr17	82061622	Silent	rs370860304	S231S	0.38
UCEC	chr17	82060896	Missense_Mutation	novel	A303D	0.45
UCEC	chr17	82064888	Missense_Mutation	rs371267525	A58T	0.21	Dus

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.1556	0.024369
BLCA	AMP	0.3897	0.00012456
CESC	DEL	0.1085	0.00067839
KIRP	AMP	0.6701	0.14801
LGG	AMP	0.0682	1.52e-05
SARC	AMP	0.2023	0.032181
SKCM	AMP	0.2834	7.0388e-08
THCA	DEL	0.002	0.221
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
UCS	0.045	Kaplan-Meier Survival Analysis
SKCM	0.014	Kaplan-Meier Survival Analysis
BRCA	0.041	Kaplan-Meier Survival Analysis
PAAD	0.0055	Kaplan-Meier Survival Analysis
BLCA	0.039	Kaplan-Meier Survival Analysis
CESC	0.05	Kaplan-Meier Survival Analysis
LAML	0.046	Kaplan-Meier Survival Analysis
GBM	0.001	Kaplan-Meier Survival Analysis
LGG	0.026	Kaplan-Meier Survival Analysis
UVM	0.026	Kaplan-Meier Survival Analysis
OV	0.013	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742