EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169727 (Gene tree)
Gene ID: 2873
Gene Symbol: GPS1
Alias: COPS1|CSN1
Full Name: G protein pathway suppressor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 6,780 bases
Position: chr17:82,050,691-82,057,470
Accession: 4549
RBP type: non-canonical RBP
Summary: This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. [provided by RefSeq, Mar 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000584460	GPS1-224	1855	-	ENSP00000462297	44 (aa)	-	J3KRY5
ENST00000581418	GPS1-214	580	-	ENSP00000462896	139 (aa)	-	J3KTB0
ENST00000580723	GPS1-213	594	-	ENSP00000462213	44 (aa)	-	J3KRY5
ENST00000320548	GPS1-202	1949	XM_017024524	ENSP00000313569	471 (aa)	XP_016880013	C9JFE4
ENST00000584229	GPS1-223	535	-	-	- (aa)	-	-
ENST00000306823	GPS1-201	1842	XM_005256350	ENSP00000302873	491 (aa)	XP_005256407	Q13098
ENST00000580627	GPS1-211	543	-	ENSP00000463823	60 (aa)	-	J3QQP2
ENST00000583009	GPS1-217	574	-	ENSP00000463514	166 (aa)	-	J3QLE8
ENST00000583486	GPS1-218	796	-	-	- (aa)	-	-
ENST00000578552	GPS1-208	1874	XM_005256353	ENSP00000462265	487 (aa)	XP_005256410	Q13098
ENST00000581578	GPS1-215	470	-	ENSP00000464571	101 (aa)	-	J3QS84
ENST00000578168	GPS1-205	583	-	ENSP00000463937	79 (aa)	-	J3QQX0
ENST00000580141	GPS1-210	924	-	ENSP00000464530	44 (aa)	-	J3KRY5
ENST00000624957	GPS1-228	1825	-	ENSP00000485641	490 (aa)	-	A0A096LPJ3
ENST00000585084	GPS1-225	997	-	ENSP00000462391	210 (aa)	-	J3KSA5
ENST00000392358	GPS1-204	2276	XM_024450718	ENSP00000376167	527 (aa)	XP_024306486	Q13098
ENST00000623691	GPS1-226	1839	XM_017024525	ENSP00000485330	486 (aa)	XP_016880014	A0A096LP07
ENST00000392357	GPS1-203	4076	-	-	- (aa)	-	-
ENST00000582327	GPS1-216	561	-	ENSP00000464575	134 (aa)	-	J3QS88
ENST00000578279	GPS1-206	875	-	-	- (aa)	-	-
ENST00000583983	GPS1-222	556	-	-	- (aa)	-	-
ENST00000623761	GPS1-227	1943	-	ENSP00000485035	526 (aa)	-	A8K070
ENST00000583885	GPS1-220	594	-	ENSP00000461965	186 (aa)	-	J3KRE8
ENST00000580716	GPS1-212	567	-	ENSP00000463690	168 (aa)	-	J3QLT0
ENST00000578392	GPS1-207	552	-	ENSP00000462705	93 (aa)	-	J3KSY1
ENST00000583641	GPS1-219	795	-	ENSP00000462029	253 (aa)	-	J3KRJ4
ENST00000578642	GPS1-209	579	-	-	- (aa)	-	-
ENST00000583961	GPS1-221	581	-	ENSP00000463381	168 (aa)	-	J3QL53

Gene Model

Click here to download ENSG00000169727's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169727's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169727	GPS1	97	60.198	FBgn0027057	CSN1b	95	61.386	Drosophila_melanogaster
ENSG00000169727	GPS1	100	98.095	ENSMUSG00000025156	Gps1	100	97.947	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000188	inactivation of MAPK activity	8943324.	TAS	Process
GO:0000338	protein deneddylation	19141280.	IDA	Process
GO:0000715	nucleotide-excision repair, DNA damage recognition	-	TAS	Process
GO:0005095	GTPase inhibitor activity	8943324.	TAS	Function
GO:0005515	protein binding	17337451.18850735.19444310.19615732.20399188.24421388.27029275.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006283	transcription-coupled nucleotide-excision repair	-	TAS	Process
GO:0007254	JNK cascade	8943324.	TAS	Process
GO:0008180	COP9 signalosome	21873635.	IBA	Component
GO:0008180	COP9 signalosome	18850735.	IDA	Component
GO:0034260	negative regulation of GTPase activity	-	IEA	Process
GO:0043687	post-translational protein modification	-	TAS	Process