EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169946 (Gene tree)
Gene ID: 23414
Gene Symbol: ZFPM2
Alias: FOG2|hFOG-2|ZNF89B|ZC2HC11B
Full Name: zinc finger protein, FOG family member 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 1,213,807 bases
Position: chr8:104,590,733-105,804,539
Accession: 16700
RBP type: canonical RBP
Summary: The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000428720	zf-met	PF12874.7	9.2e-06	1	1
ENSP00000430757	zf-met	PF12874.7	9.2e-06	1	1
ENSP00000384179	zf-met	PF12874.7	2.8e-05	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11076749	FOG-2, a novel F-box containing protein, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline.	Development	2000 Dec	Clifford R	-
15630478	fog-2 and the evolution of self-fertile hermaphroditism in Caenorhabditis.	PLoS Biol	2005 Jan	Nayak S	-
28952134	Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data.	Med Oncol	2017 Sep 26	Vastrad B	doi: 10.1007/s12032-017-1043-x.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000517361	ZFPM2-203	3300	-	ENSP00000428720	1019 (aa)	-	E7ET52
ENST00000518180	ZFPM2-204	596	-	-	- (aa)	-	-
ENST00000522296	ZFPM2-209	3312	-	-	- (aa)	-	-
ENST00000524235	ZFPM2-210	574	-	-	- (aa)	-	-
ENST00000407775	ZFPM2-201	4700	XM_011516947	ENSP00000384179	1151 (aa)	XP_011515249	Q8WW38
ENST00000511341	ZFPM2-202	1582	-	-	- (aa)	-	-
ENST00000521923	ZFPM2-207	720	-	-	- (aa)	-	-
ENST00000520027	ZFPM2-205	594	-	ENSP00000428149	26 (aa)	-	E5RJX0
ENST00000520492	ZFPM2-206	3960	-	ENSP00000430757	1019 (aa)	-	E7ET52
ENST00000522160	ZFPM2-208	468	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000169946's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05206	MicroRNAs in cancer	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000169946	Body Weights and Measures	8.1481609117029E-5	17903300
ENSG00000169946	Aorta	6.25443021795569E-5	17903303
ENSG00000169946	Erythrocyte Indices	7.15236512630605E-8	17903294
ENSG00000169946	Hip	5.61694877523141E-8	17903296
ENSG00000169946	Mental Competency	3.58286926405276E-9	17903295
ENSG00000169946	Mental Competency	2.87449530225591E-13	17903295
ENSG00000169946	Cardiovascular Physiological Phenomena	6.1240000E-005	-
ENSG00000169946	Cardiovascular Physiological Phenomena	3.1150000E-005	-
ENSG00000169946	Job Satisfaction	6.6110000E-005	-
ENSG00000169946	Platelet Function Tests	1.1415300E-005	-
ENSG00000169946	Platelet Function Tests	2.2932100E-005	-
ENSG00000169946	Tuberculosis	3E-6	24057671
ENSG00000169946	Vascular Endothelial Growth Factors	5E-23	21757650
ENSG00000169946	Platelet Count	3E-8	26805783
ENSG00000169946	Vascular Calcification	6E-6	23870195
ENSG00000169946	Vascular Endothelial Growth Factors	4E-55	26910538
ENSG00000169946	Platelet Count	4E-17	22139419
ENSG00000169946	Gastrointestinal Microbiome	3E-6	26528553
ENSG00000169946	S-(3-hydroxypropyl)cysteine N-acetate	2E-6	26053186
ENSG00000169946	Smoking	2E-6	26053186
ENSG00000169946	Venous Thromboembolism	5E-7	25772935

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000169946	rs35783704	8	104954030	A	Systolic blood pressure	28739976	[0.37-0.85] unit decrease	0.609	EFO_0006335
ENSG00000169946	rs35783704	8	104954030	A	Systolic blood pressure	28739976	[0.27-0.56] unit decrease	0.414	EFO_0006335
ENSG00000169946	rs6993770	8	105569300	T	Mean platelet volume	27863252	[0.041-0.057] unit increase	0.04908564	EFO_0004584
ENSG00000169946	rs1460237	8	104829627	?	Age-related hearing impairment	24939585	[NR] unit decrease	0.452	EFO_0005782
ENSG00000169946	rs6993770	8	105569300	A	Platelet count	26805783	[3.07-6.41] unit increase	4.74	EFO_0004309
ENSG00000169946	rs6993770	8	105569300	A	Vascular endothelial growth factor levels	26910538	[0.14-0.18] unit increase	0.16	EFO_0004762
ENSG00000169946	rs284491	8	104946405	T	Glaucoma (low intraocular pressure)	26752265		1.52	EFO_1001022
ENSG00000169946	rs17217757	8	105601093	G	Tuberculosis	24057671	[NR]	2.3256	Orphanet_3389
ENSG00000169946	rs6999452	8	105384888	?	Gut microbiome composition (summer)	26528553	[0.41-1.02] unit decrease	0.7132617	EFO_0007753
ENSG00000169946	rs4602861	8	105578478	A	Venous thromboembolism	25772935	[1.13-1.27]	1.2	EFO_0004286
ENSG00000169946	rs142507408	8	105443330	?	3-hydroxypropylmercapturic acid levels in smokers	26053186	[NR] unit increase	1.6373	EFO_0004318\|EFO_0007014
ENSG00000169946	rs6993770	8	105569300	A	Platelet count	22139419	[2.81-4.52] 10^9/l increase	3.668	EFO_0004309
ENSG00000169946	rs977396	8	104980468	?	Response to antipsychotic treatment	20195266			GO_0097333
ENSG00000169946	rs2622633	8	105497747	A	Coronary artery calcification	23870195	[0.1-0.3] unit increase	0.2	EFO_0004723
ENSG00000169946	rs4734806	8	104688452	G	Periodontitis (DPAL)	24024966	[0.12-0.30] unit decrease	0.2075	EFO_0000649
ENSG00000169946	rs16873418	8	105579917	G	Blood protein levels	28240269	[0.19-0.37] unit increase	0.2804	EFO_0008162
ENSG00000169946	rs16873418	8	105579917	G	Blood protein levels	28240269	[0.22-0.41] unit increase	0.3148	EFO_0008310
ENSG00000169946	rs1460583	8	105096365	C	Schizophrenia	28991256	[1.03-1.06]	1.0449321	EFO_0000692
ENSG00000169946	rs12678274	8	105247887	?	Cognitive function	28808816			EFO_0008354
ENSG00000169946	rs28416651	8	105552424	A	Coronary artery disease	29212778	[0.024-0.048] unit decrease	0.036	EFO_0000378
ENSG00000169946	rs2342781	8	105253492	C	Coronary artery disease	29212778	[0.019-0.041] unit decrease	0.0297	EFO_0000378
ENSG00000169946	rs10093110	8	105553186	A	Coronary artery disease	29212778	[0.021-0.043] unit decrease	0.0319	EFO_0000378
ENSG00000169946	rs7008697	8	105547491	A	Educational attainment (MTAG)	30038396	[0.0055-0.0105] unit decrease	0.008	EFO_0004784
ENSG00000169946	rs1375961	8	105535755	T	Self-reported math ability	30038396	[0.012-0.024] unit decrease	0.0183	EFO_0004875
ENSG00000169946	rs7837523	8	105517074	A	Self-reported math ability (MTAG)	30038396	[0.009-0.0172] unit decrease	0.0131	EFO_0004875
ENSG00000169946	rs7837523	8	105517074	A	Highest math class taken (MTAG)	30038396	[0.0092-0.0166] unit decrease	0.0129	EFO_0004875
ENSG00000169946	rs4734804	8	104684620	A	Irritable mood	29500382	z score increase	5.51	EFO_0009594
ENSG00000169946	rs4734879	8	105570896	G	Blood protein levels	29875488	[0.25-0.37] unit decrease	0.31	EFO_0007937
ENSG00000169946	rs57942103	8	105501233	C	Blood protein levels	29875488	[0.16-0.28] unit increase	0.22	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.24-0.36] unit decrease	0.3	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.2-0.32] unit decrease	0.26	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.14-0.26] unit decrease	0.2	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.14-0.26] unit decrease	0.2	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.16-0.28] unit decrease	0.22	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.14-0.26] unit decrease	0.2	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.13-0.25] unit decrease	0.19	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.2-0.32] unit decrease	0.26	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.13-0.25] unit decrease	0.19	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.18-0.3] unit decrease	0.24	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.18-0.3] unit decrease	0.24	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.17-0.29] unit decrease	0.23	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.15-0.27] unit decrease	0.21	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.15-0.27] unit decrease	0.21	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.19-0.31] unit decrease	0.25	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.13-0.25] unit decrease	0.19	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.23-0.35] unit decrease	0.29	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.15-0.27] unit decrease	0.21	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.12-0.24] unit decrease	0.18	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.2-0.32] unit decrease	0.26	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.13-0.25] unit increase	0.19	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.13-0.25] unit decrease	0.19	EFO_0007937
ENSG00000169946	rs6993770	8	105569300	T	Blood protein levels	29875488	[0.15-0.27] unit decrease	0.21	EFO_0007937
ENSG00000169946	rs2343592	8	105560042	?	Platelet count	29403010	[0.021-0.039] unit decrease novel	0.03023	EFO_0004309
ENSG00000169946	rs3832566	8	105561297	C	White blood cell count (basophil)	27863252	[0.016-0.031] unit decrease	0.02347503	EFO_0005090
ENSG00000169946	rs6993770	8	105569300	T	Platelet count	27863252	[0.062-0.078] unit decrease	0.06999471	EFO_0004309
ENSG00000169946	rs6993770	8	105569300	T	Platelet distribution width	27863252	[0.053-0.068] unit increase	0.0605383	EFO_0007984
ENSG00000169946	rs6993770	8	105569300	T	Plateletcrit	27863252	[0.045-0.061] unit decrease	0.05340481	EFO_0007985
ENSG00000169946	rs6993770	8	105569300	T	Interleukin-12p70 levels	27989323	[0.055-0.129] SD units decrease	0.0918	EFO_0004753
ENSG00000169946	rs12678719	8	105503826	G	PR interval	30046033	[0.55-1.05] ms increase	0.8	EFO_0004462
ENSG00000169946	rs284489	8	104945792	?	Glaucoma (primary open-angle)	22570617	[1.39-1.89]	1.61	EFO_0004190
ENSG00000169946	rs16872085	8	104945312	?	Sudden cardiac arrest	21658281	[1.44-2.33]	1.83	EFO_0004278
ENSG00000169946	rs6993770	8	105569300	T	Vascular endothelial growth factor levels	21757650			EFO_0004762
ENSG00000169946	rs72679151	8	104614889	C	Blood protein levels	30072576	[0.15-0.27] unit decrease	0.211	EFO_0007937
ENSG00000169946	rs11774829	8	104966140	A	Systolic blood pressure	30578418	[0.34-0.53] mmHg decrease	0.4372	EFO_0006335
ENSG00000169946	rs1113601	8	105325989	?	Takayasu arteritis	25604533	[NR]	1.7857143	EFO_1001857
ENSG00000169946	rs11774829	8	104966140	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000169946	rs11774829	8	104966140	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000169946	rs17210179	8	105333241	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000169946	rs1350723	8	105218944	?	White blood cell count	30595370			EFO_0004308
ENSG00000169946	rs7832219	8	105566749	?	White blood cell count	30595370			EFO_0004308
ENSG00000169946	rs6993770	8	105569300	?	Red blood cell count	30595370			EFO_0004305
ENSG00000169946	rs35783704	8	104954030	?	Cardiovascular disease	30595370			EFO_0000319
ENSG00000169946	rs13263073	8	104969988	A	Pulse pressure	30578418	[0.13-0.24] mmHg increase	0.1863	EFO_0005763
ENSG00000169946	rs1460583	8	105096365	C	Schizophrenia	30285260	[1.03-1.07]	1.0515248	EFO_0000692
ENSG00000169946	rs12546444	8	105346392	A	Breast cancer	29059683	[1.04-1.1] (Oncoarray)	1.0752687	EFO_0000305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169946's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169946	ZFPM2	100	64.341	ENSAPOG00000019134	zfpm2a	100	63.211	Acanthochromis_polyacanthus
ENSG00000169946	ZFPM2	100	100.000	ENSAMEG00000005726	ZFPM2	100	96.658	Ailuropoda_melanoleuca
ENSG00000169946	ZFPM2	100	63.372	ENSACIG00000003230	zfpm2a	99	63.470	Amphilophus_citrinellus
ENSG00000169946	ZFPM2	89	31.927	ENSACIG00000015211	zfpm1	94	34.848	Amphilophus_citrinellus
ENSG00000169946	ZFPM2	100	64.155	ENSAOCG00000000117	zfpm2a	100	64.343	Amphiprion_ocellaris
ENSG00000169946	ZFPM2	100	64.244	ENSAPEG00000021820	zfpm2a	97	63.989	Amphiprion_percula
ENSG00000169946	ZFPM2	94	30.820	ENSATEG00000005697	zfpm1	82	69.697	Anabas_testudineus
ENSG00000169946	ZFPM2	100	64.237	ENSATEG00000024763	zfpm2a	96	63.958	Anabas_testudineus
ENSG00000169946	ZFPM2	96	90.501	ENSAPLG00000015698	ZFPM2	100	90.501	Anas_platyrhynchos
ENSG00000169946	ZFPM2	100	92.308	ENSACAG00000009858	ZFPM2	98	86.173	Anolis_carolinensis
ENSG00000169946	ZFPM2	100	100.000	ENSANAG00000029770	ZFPM2	100	98.921	Aotus_nancymaae
ENSG00000169946	ZFPM2	74	69.697	ENSACLG00000001201	zfpm1	67	69.697	Astatotilapia_calliptera
ENSG00000169946	ZFPM2	100	63.016	ENSACLG00000025322	zfpm2a	100	62.237	Astatotilapia_calliptera
ENSG00000169946	ZFPM2	100	65.302	ENSAMXG00000032770	zfpm2a	100	64.343	Astyanax_mexicanus
ENSG00000169946	ZFPM2	93	51.095	ENSAMXG00000017011	zfpm2b	97	50.289	Astyanax_mexicanus
ENSG00000169946	ZFPM2	53	51.948	ENSAMXG00000032676	zfpm1	84	43.590	Astyanax_mexicanus
ENSG00000169946	ZFPM2	60	50.667	ENSBTAG00000015766	ZFPM1	80	75.758	Bos_taurus
ENSG00000169946	ZFPM2	100	100.000	ENSBTAG00000001649	ZFPM2	99	93.652	Bos_taurus
ENSG00000169946	ZFPM2	100	100.000	ENSCJAG00000006642	ZFPM2	100	98.262	Callithrix_jacchus
ENSG00000169946	ZFPM2	79	75.758	ENSCJAG00000012840	ZFPM1	94	42.982	Callithrix_jacchus
ENSG00000169946	ZFPM2	100	100.000	ENSCAFG00000000678	ZFPM2	100	95.584	Canis_familiaris
ENSG00000169946	ZFPM2	50	74.286	ENSCAFG00020004606	ZFPM1	82	73.684	Canis_lupus_dingo
ENSG00000169946	ZFPM2	100	100.000	ENSCAFG00020003252	ZFPM2	99	94.897	Canis_lupus_dingo
ENSG00000169946	ZFPM2	97	93.902	ENSCHIG00000015764	ZFPM2	99	93.902	Capra_hircus
ENSG00000169946	ZFPM2	58	61.538	ENSCHIG00000010239	ZFPM1	90	61.538	Capra_hircus
ENSG00000169946	ZFPM2	100	100.000	ENSTSYG00000034291	ZFPM2	100	98.002	Carlito_syrichta
ENSG00000169946	ZFPM2	96	90.051	ENSCAPG00000009497	ZFPM2	90	90.051	Cavia_aperea
ENSG00000169946	ZFPM2	100	100.000	ENSCPOG00000014225	ZFPM2	100	90.392	Cavia_porcellus
ENSG00000169946	ZFPM2	65	75.758	ENSCPOG00000024281	ZFPM1	82	63.830	Cavia_porcellus
ENSG00000169946	ZFPM2	79	75.758	ENSCCAG00000036250	ZFPM1	94	42.982	Cebus_capucinus
ENSG00000169946	ZFPM2	100	100.000	ENSCCAG00000031529	ZFPM2	100	98.262	Cebus_capucinus
ENSG00000169946	ZFPM2	96	99.076	ENSCATG00000031488	ZFPM2	100	99.075	Cercocebus_atys
ENSG00000169946	ZFPM2	69	75.758	ENSCATG00000030036	ZFPM1	85	50.000	Cercocebus_atys
ENSG00000169946	ZFPM2	100	100.000	ENSCLAG00000005797	ZFPM2	97	90.536	Chinchilla_lanigera
ENSG00000169946	ZFPM2	92	99.149	ENSCSAG00000011798	ZFPM2	100	99.149	Chlorocebus_sabaeus
ENSG00000169946	ZFPM2	68	75.758	ENSCSAG00000003107	ZFPM1	88	42.202	Chlorocebus_sabaeus
ENSG00000169946	ZFPM2	99	95.374	ENSCHOG00000010127	ZFPM2	99	92.321	Choloepus_hoffmanni
ENSG00000169946	ZFPM2	73	38.501	ENSCPBG00000023499	ZFPM1	100	31.878	Chrysemys_picta_bellii
ENSG00000169946	ZFPM2	100	90.481	ENSCPBG00000000875	ZFPM2	100	90.637	Chrysemys_picta_bellii
ENSG00000169946	ZFPM2	100	99.215	ENSCANG00000033058	ZFPM2	100	99.033	Colobus_angolensis_palliatus
ENSG00000169946	ZFPM2	96	91.150	ENSCGRG00001009999	Zfpm2	96	91.150	Cricetulus_griseus_chok1gshd
ENSG00000169946	ZFPM2	73	72.727	ENSCGRG00001021400	Zfpm1	96	41.667	Cricetulus_griseus_chok1gshd
ENSG00000169946	ZFPM2	51	72.727	ENSCGRG00000018408	Zfpm1	91	41.791	Cricetulus_griseus_crigri
ENSG00000169946	ZFPM2	71	88.998	ENSCGRG00000008914	Zfpm2	94	88.998	Cricetulus_griseus_crigri
ENSG00000169946	ZFPM2	60	69.697	ENSCSEG00000000359	zfpm1	86	31.825	Cynoglossus_semilaevis
ENSG00000169946	ZFPM2	100	62.741	ENSCSEG00000010109	zfpm2a	100	61.793	Cynoglossus_semilaevis
ENSG00000169946	ZFPM2	99	64.397	ENSCVAG00000009516	zfpm2a	100	62.891	Cyprinodon_variegatus
ENSG00000169946	ZFPM2	100	64.321	ENSDARG00000040123	zfpm2a	99	64.706	Danio_rerio
ENSG00000169946	ZFPM2	78	32.020	ENSDARG00000041572	zfpm1	80	35.000	Danio_rerio
ENSG00000169946	ZFPM2	90	60.784	ENSDARG00000100560	zfpm2b	85	60.784	Danio_rerio
ENSG00000169946	ZFPM2	99	95.717	ENSDNOG00000045385	ZFPM2	100	95.717	Dasypus_novemcinctus
ENSG00000169946	ZFPM2	100	96.154	ENSDORG00000002573	Zfpm2	100	95.830	Dipodomys_ordii
ENSG00000169946	ZFPM2	61	49.057	ENSEBUG00000007949	-	77	49.057	Eptatretus_burgeri
ENSG00000169946	ZFPM2	73	68.293	ENSEBUG00000016789	-	70	68.293	Eptatretus_burgeri
ENSG00000169946	ZFPM2	50	68.293	ENSEASG00005000337	ZFPM1	84	68.293	Equus_asinus_asinus
ENSG00000169946	ZFPM2	100	100.000	ENSEASG00005001158	ZFPM2	100	95.780	Equus_asinus_asinus
ENSG00000169946	ZFPM2	100	100.000	ENSECAG00000020172	ZFPM2	100	96.177	Equus_caballus
ENSG00000169946	ZFPM2	100	100.000	ENSEEUG00000009933	ZFPM2	100	93.462	Erinaceus_europaeus
ENSG00000169946	ZFPM2	74	69.697	ENSELUG00000013952	zfpm1	85	69.697	Esox_lucius
ENSG00000169946	ZFPM2	100	62.793	ENSELUG00000005828	zfpm2a	100	62.448	Esox_lucius
ENSG00000169946	ZFPM2	64	72.973	ENSFCAG00000041829	ZFPM1	92	49.333	Felis_catus
ENSG00000169946	ZFPM2	100	100.000	ENSFCAG00000009078	ZFPM2	100	97.046	Felis_catus
ENSG00000169946	ZFPM2	99	90.737	ENSFALG00000006051	ZFPM2	100	90.737	Ficedula_albicollis
ENSG00000169946	ZFPM2	96	84.308	ENSFDAG00000005377	ZFPM2	95	84.308	Fukomys_damarensis
ENSG00000169946	ZFPM2	68	69.697	ENSFHEG00000011678	zfpm1	76	69.697	Fundulus_heteroclitus
ENSG00000169946	ZFPM2	100	64.507	ENSFHEG00000010125	zfpm2a	100	63.442	Fundulus_heteroclitus
ENSG00000169946	ZFPM2	96	63.754	ENSGMOG00000005633	zfpm2a	100	63.754	Gadus_morhua
ENSG00000169946	ZFPM2	65	75.758	ENSGALG00000049065	ZFPM1	93	42.466	Gallus_gallus
ENSG00000169946	ZFPM2	100	92.308	ENSGALG00000040079	ZFPM2	100	90.009	Gallus_gallus
ENSG00000169946	ZFPM2	100	57.404	ENSGAFG00000019805	zfpm2a	99	57.401	Gambusia_affinis
ENSG00000169946	ZFPM2	63	45.455	ENSGAFG00000015163	zfpm1	99	35.474	Gambusia_affinis
ENSG00000169946	ZFPM2	96	62.687	ENSGACG00000004783	zfpm2a	100	63.184	Gasterosteus_aculeatus
ENSG00000169946	ZFPM2	83	75.758	ENSGAGG00000001403	ZFPM1	81	75.758	Gopherus_agassizii
ENSG00000169946	ZFPM2	89	89.097	ENSGAGG00000019073	ZFPM2	97	89.097	Gopherus_agassizii
ENSG00000169946	ZFPM2	100	100.000	ENSGGOG00000011645	ZFPM2	100	99.392	Gorilla_gorilla
ENSG00000169946	ZFPM2	74	69.697	ENSHBUG00000018289	zfpm1	100	33.411	Haplochromis_burtoni
ENSG00000169946	ZFPM2	100	63.173	ENSHBUG00000016317	zfpm2a	100	62.458	Haplochromis_burtoni
ENSG00000169946	ZFPM2	100	96.154	ENSHGLG00000015400	ZFPM2	99	87.544	Heterocephalus_glaber_female
ENSG00000169946	ZFPM2	66	75.758	ENSHGLG00000010104	ZFPM1	97	45.122	Heterocephalus_glaber_female
ENSG00000169946	ZFPM2	100	96.154	ENSHGLG00100008736	ZFPM2	99	87.633	Heterocephalus_glaber_male
ENSG00000169946	ZFPM2	88	31.939	ENSHCOG00000014898	zfpm1	90	32.831	Hippocampus_comes
ENSG00000169946	ZFPM2	100	69.231	ENSHCOG00000014205	zfpm2a	100	62.644	Hippocampus_comes
ENSG00000169946	ZFPM2	98	41.383	ENSIPUG00000018876	zfpm2b	94	40.655	Ictalurus_punctatus
ENSG00000169946	ZFPM2	100	64.425	ENSIPUG00000022508	zfpm2	100	63.621	Ictalurus_punctatus
ENSG00000169946	ZFPM2	79	50.847	ENSIPUG00000019070	zfpm1	69	72.727	Ictalurus_punctatus
ENSG00000169946	ZFPM2	59	71.053	ENSSTOG00000027139	ZFPM1	83	49.254	Ictidomys_tridecemlineatus
ENSG00000169946	ZFPM2	100	100.000	ENSSTOG00000020729	ZFPM2	100	97.394	Ictidomys_tridecemlineatus
ENSG00000169946	ZFPM2	100	100.000	ENSJJAG00000000192	Zfpm2	100	93.223	Jaculus_jaculus
ENSG00000169946	ZFPM2	65	75.758	ENSJJAG00000008137	Zfpm1	78	63.043	Jaculus_jaculus
ENSG00000169946	ZFPM2	56	42.246	ENSKMAG00000000907	zfpm1	95	34.583	Kryptolebias_marmoratus
ENSG00000169946	ZFPM2	99	65.049	ENSKMAG00000002098	zfpm2a	100	63.277	Kryptolebias_marmoratus
ENSG00000169946	ZFPM2	64	50.704	ENSLBEG00000007278	zfpm1	81	69.697	Labrus_bergylta
ENSG00000169946	ZFPM2	100	63.173	ENSLBEG00000001892	zfpm2a	100	62.426	Labrus_bergylta
ENSG00000169946	ZFPM2	96	75.433	ENSLACG00000000296	ZFPM2	100	75.764	Latimeria_chalumnae
ENSG00000169946	ZFPM2	77	65.217	ENSLACG00000018391	ZFPM1	81	65.217	Latimeria_chalumnae
ENSG00000169946	ZFPM2	100	69.862	ENSLOCG00000009425	zfpm2a	100	69.862	Lepisosteus_oculatus
ENSG00000169946	ZFPM2	77	38.500	ENSLOCG00000002480	zfpm1	74	38.250	Lepisosteus_oculatus
ENSG00000169946	ZFPM2	52	75.758	ENSLAFG00000013561	ZFPM1	90	75.758	Loxodonta_africana
ENSG00000169946	ZFPM2	100	100.000	ENSLAFG00000010342	ZFPM2	100	95.917	Loxodonta_africana
ENSG00000169946	ZFPM2	74	75.758	ENSMFAG00000036335	ZFPM1	84	61.111	Macaca_fascicularis
ENSG00000169946	ZFPM2	100	100.000	ENSMFAG00000045726	ZFPM2	100	99.305	Macaca_fascicularis
ENSG00000169946	ZFPM2	100	100.000	ENSMMUG00000007721	ZFPM2	100	99.215	Macaca_mulatta
ENSG00000169946	ZFPM2	66	75.758	ENSMMUG00000047141	ZFPM1	87	43.119	Macaca_mulatta
ENSG00000169946	ZFPM2	66	75.758	ENSMNEG00000041734	ZFPM1	81	50.000	Macaca_nemestrina
ENSG00000169946	ZFPM2	100	100.000	ENSMNEG00000034635	ZFPM2	100	99.218	Macaca_nemestrina
ENSG00000169946	ZFPM2	100	100.000	ENSMLEG00000038244	ZFPM2	100	99.120	Mandrillus_leucophaeus
ENSG00000169946	ZFPM2	100	63.813	ENSMAMG00000003375	zfpm2a	92	63.660	Mastacembelus_armatus
ENSG00000169946	ZFPM2	82	69.697	ENSMAMG00000012173	zfpm1	82	69.697	Mastacembelus_armatus
ENSG00000169946	ZFPM2	100	63.234	ENSMZEG00005012352	zfpm2a	100	62.511	Maylandia_zebra
ENSG00000169946	ZFPM2	74	69.697	ENSMZEG00005016182	zfpm1	67	69.697	Maylandia_zebra
ENSG00000169946	ZFPM2	96	90.349	ENSMGAG00000012374	ZFPM2	100	90.349	Meleagris_gallopavo
ENSG00000169946	ZFPM2	79	40.741	ENSMAUG00000017930	Zfpm1	99	40.741	Mesocricetus_auratus
ENSG00000169946	ZFPM2	100	96.154	ENSMAUG00000019448	Zfpm2	100	91.090	Mesocricetus_auratus
ENSG00000169946	ZFPM2	100	100.000	ENSMICG00000001099	ZFPM2	100	98.002	Microcebus_murinus
ENSG00000169946	ZFPM2	65	75.758	ENSMICG00000032078	ZFPM1	82	75.758	Microcebus_murinus
ENSG00000169946	ZFPM2	78	49.057	ENSMOCG00000001709	Zfpm1	97	41.818	Microtus_ochrogaster
ENSG00000169946	ZFPM2	100	100.000	ENSMOCG00000013738	Zfpm2	99	92.818	Microtus_ochrogaster
ENSG00000169946	ZFPM2	100	63.854	ENSMMOG00000017933	zfpm2a	99	63.886	Mola_mola
ENSG00000169946	ZFPM2	100	92.308	ENSMODG00000005359	ZFPM2	100	91.573	Monodelphis_domestica
ENSG00000169946	ZFPM2	51	52.113	ENSMALG00000009835	zfpm1	69	49.123	Monopterus_albus
ENSG00000169946	ZFPM2	100	63.961	ENSMALG00000007543	zfpm2a	100	63.536	Monopterus_albus
ENSG00000169946	ZFPM2	100	100.000	MGP_CAROLIEiJ_G0019763	Zfpm2	100	94.179	Mus_caroli
ENSG00000169946	ZFPM2	85	41.667	MGP_CAROLIEiJ_G0031656	Zfpm1	97	41.667	Mus_caroli
ENSG00000169946	ZFPM2	79	75.758	ENSMUSG00000049577	Zfpm1	97	42.593	Mus_musculus
ENSG00000169946	ZFPM2	100	100.000	ENSMUSG00000022306	Zfpm2	100	94.897	Mus_musculus
ENSG00000169946	ZFPM2	100	100.000	MGP_PahariEiJ_G0019772	Zfpm2	100	93.918	Mus_pahari
ENSG00000169946	ZFPM2	78	52.830	MGP_PahariEiJ_G0023254	Zfpm1	97	43.519	Mus_pahari
ENSG00000169946	ZFPM2	79	75.758	MGP_SPRETEiJ_G0032774	Zfpm1	97	40.741	Mus_spretus
ENSG00000169946	ZFPM2	100	100.000	MGP_SPRETEiJ_G0020660	Zfpm2	100	93.571	Mus_spretus
ENSG00000169946	ZFPM2	100	100.000	ENSMPUG00000005985	ZFPM2	100	96.959	Mustela_putorius_furo
ENSG00000169946	ZFPM2	96	94.575	ENSMLUG00000010148	ZFPM2	100	94.575	Myotis_lucifugus
ENSG00000169946	ZFPM2	100	96.154	ENSNGAG00000019414	Zfpm2	100	95.569	Nannospalax_galili
ENSG00000169946	ZFPM2	58	68.293	ENSNGAG00000015027	Zfpm1	74	68.293	Nannospalax_galili
ENSG00000169946	ZFPM2	76	49.153	ENSNBRG00000000569	zfpm1	93	42.466	Neolamprologus_brichardi
ENSG00000169946	ZFPM2	100	63.052	ENSNBRG00000006933	zfpm2a	100	62.943	Neolamprologus_brichardi
ENSG00000169946	ZFPM2	54	75.758	ENSNLEG00000000491	ZFPM1	88	42.982	Nomascus_leucogenys
ENSG00000169946	ZFPM2	100	100.000	ENSNLEG00000003937	ZFPM2	100	99.218	Nomascus_leucogenys
ENSG00000169946	ZFPM2	60	92.825	ENSMEUG00000010666	-	60	92.825	Notamacropus_eugenii
ENSG00000169946	ZFPM2	96	86.531	ENSODEG00000001176	ZFPM2	95	86.531	Octodon_degus
ENSG00000169946	ZFPM2	70	68.293	ENSODEG00000004547	ZFPM1	95	46.250	Octodon_degus
ENSG00000169946	ZFPM2	100	62.512	ENSONIG00000000152	zfpm2a	100	61.682	Oreochromis_niloticus
ENSG00000169946	ZFPM2	76	49.153	ENSONIG00000010766	zfpm1	97	42.478	Oreochromis_niloticus
ENSG00000169946	ZFPM2	92	87.872	ENSOANG00000011618	-	100	87.872	Ornithorhynchus_anatinus
ENSG00000169946	ZFPM2	100	96.154	ENSOCUG00000005930	ZFPM2	100	95.573	Oryctolagus_cuniculus
ENSG00000169946	ZFPM2	100	63.715	ENSORLG00000003240	zfpm2a	100	62.321	Oryzias_latipes
ENSG00000169946	ZFPM2	74	69.697	ENSORLG00000026867	zfpm1	72	69.697	Oryzias_latipes
ENSG00000169946	ZFPM2	74	69.697	ENSORLG00020016135	zfpm1	81	69.697	Oryzias_latipes_hni
ENSG00000169946	ZFPM2	100	63.269	ENSORLG00020022496	zfpm2a	100	62.395	Oryzias_latipes_hni
ENSG00000169946	ZFPM2	80	69.697	ENSORLG00015006342	zfpm1	81	69.697	Oryzias_latipes_hsok
ENSG00000169946	ZFPM2	94	31.230	ENSOMEG00000016199	zfpm1	100	30.502	Oryzias_melastigma
ENSG00000169946	ZFPM2	100	63.715	ENSOMEG00000007591	zfpm2a	100	62.654	Oryzias_melastigma
ENSG00000169946	ZFPM2	69	65.909	ENSOGAG00000028472	ZFPM1	89	54.545	Otolemur_garnettii
ENSG00000169946	ZFPM2	99	96.215	ENSOGAG00000027431	ZFPM2	100	96.215	Otolemur_garnettii
ENSG00000169946	ZFPM2	100	100.000	ENSOARG00000015495	ZFPM2	98	95.357	Ovis_aries
ENSG00000169946	ZFPM2	100	100.000	ENSPPAG00000014102	ZFPM2	99	99.736	Pan_paniscus
ENSG00000169946	ZFPM2	100	100.000	ENSPPRG00000010402	ZFPM2	100	96.959	Panthera_pardus
ENSG00000169946	ZFPM2	100	100.000	ENSPTIG00000017006	ZFPM2	100	96.834	Panthera_tigris_altaica
ENSG00000169946	ZFPM2	100	100.000	ENSPTRG00000020498	ZFPM2	100	99.566	Pan_troglodytes
ENSG00000169946	ZFPM2	66	75.758	ENSPTRG00000008455	ZFPM1	94	42.982	Pan_troglodytes
ENSG00000169946	ZFPM2	100	100.000	ENSPANG00000017626	ZFPM2	100	99.131	Papio_anubis
ENSG00000169946	ZFPM2	72	75.758	ENSPANG00000005497	ZFPM1	87	50.000	Papio_anubis
ENSG00000169946	ZFPM2	74	66.667	ENSPKIG00000003731	zfpm1	74	66.667	Paramormyrops_kingsleyae
ENSG00000169946	ZFPM2	100	65.982	ENSPKIG00000018109	ZFPM2	100	65.514	Paramormyrops_kingsleyae
ENSG00000169946	ZFPM2	100	54.124	ENSPKIG00000025607	ZFPM2	100	54.038	Paramormyrops_kingsleyae
ENSG00000169946	ZFPM2	99	90.339	ENSPSIG00000004514	ZFPM2	100	90.339	Pelodiscus_sinensis
ENSG00000169946	ZFPM2	100	62.271	ENSPMGG00000022161	zfpm2a	98	62.117	Periophthalmus_magnuspinnatus
ENSG00000169946	ZFPM2	93	31.707	ENSPMGG00000002005	zfpm1	87	48.571	Periophthalmus_magnuspinnatus
ENSG00000169946	ZFPM2	100	100.000	ENSPEMG00000008866	Zfpm2	100	93.484	Peromyscus_maniculatus_bairdii
ENSG00000169946	ZFPM2	68	75.758	ENSPEMG00000000468	Zfpm1	91	41.818	Peromyscus_maniculatus_bairdii
ENSG00000169946	ZFPM2	67	35.150	ENSPMAG00000008800	-	100	36.005	Petromyzon_marinus
ENSG00000169946	ZFPM2	99	89.594	ENSPCIG00000015553	ZFPM2	99	91.984	Phascolarctos_cinereus
ENSG00000169946	ZFPM2	88	32.423	ENSPCIG00000007500	ZFPM1	100	32.986	Phascolarctos_cinereus
ENSG00000169946	ZFPM2	96	62.724	ENSPFOG00000014002	zfpm2a	100	63.158	Poecilia_formosa
ENSG00000169946	ZFPM2	100	63.758	ENSPLAG00000014386	zfpm2a	100	63.985	Poecilia_latipinna
ENSG00000169946	ZFPM2	96	30.476	ENSPLAG00000013968	zfpm1	94	36.242	Poecilia_latipinna
ENSG00000169946	ZFPM2	99	64.127	ENSPMEG00000013771	zfpm2a	99	64.355	Poecilia_mexicana
ENSG00000169946	ZFPM2	84	42.529	ENSPMEG00000019544	zfpm1	100	34.951	Poecilia_mexicana
ENSG00000169946	ZFPM2	96	30.655	ENSPREG00000019479	zfpm1	89	36.364	Poecilia_reticulata
ENSG00000169946	ZFPM2	100	63.908	ENSPREG00000016198	zfpm2a	100	62.563	Poecilia_reticulata
ENSG00000169946	ZFPM2	100	100.000	ENSPPYG00000018814	ZFPM2	100	97.917	Pongo_abelii
ENSG00000169946	ZFPM2	74	75.758	ENSPCAG00000014128	ZFPM1	79	75.758	Procavia_capensis
ENSG00000169946	ZFPM2	58	75.758	ENSPCOG00000016313	ZFPM1	94	75.758	Propithecus_coquereli
ENSG00000169946	ZFPM2	100	100.000	ENSPCOG00000019118	ZFPM2	100	97.567	Propithecus_coquereli
ENSG00000169946	ZFPM2	66	75.758	ENSPVAG00000005587	ZFPM1	91	39.252	Pteropus_vampyrus
ENSG00000169946	ZFPM2	100	100.000	ENSPVAG00000016508	ZFPM2	97	96.518	Pteropus_vampyrus
ENSG00000169946	ZFPM2	100	63.269	ENSPNYG00000003709	zfpm2a	100	63.144	Pundamilia_nyererei
ENSG00000169946	ZFPM2	96	30.381	ENSPNYG00000006516	zfpm1	100	33.643	Pundamilia_nyererei
ENSG00000169946	ZFPM2	100	65.171	ENSPNAG00000010580	zfpm2a	100	64.021	Pygocentrus_nattereri
ENSG00000169946	ZFPM2	85	46.154	ENSPNAG00000017014	zfpm1	85	46.154	Pygocentrus_nattereri
ENSG00000169946	ZFPM2	100	47.418	ENSPNAG00000029318	zfpm2b	100	47.160	Pygocentrus_nattereri
ENSG00000169946	ZFPM2	72	75.758	ENSRNOG00000043077	Zfpm1	97	41.818	Rattus_norvegicus
ENSG00000169946	ZFPM2	100	96.154	ENSRNOG00000004109	Zfpm2	99	94.839	Rattus_norvegicus
ENSG00000169946	ZFPM2	100	99.044	ENSRBIG00000031856	ZFPM2	98	99.076	Rhinopithecus_bieti
ENSG00000169946	ZFPM2	100	99.044	ENSRROG00000032254	ZFPM2	100	99.044	Rhinopithecus_roxellana
ENSG00000169946	ZFPM2	100	100.000	ENSSBOG00000021615	ZFPM2	100	98.697	Saimiri_boliviensis_boliviensis
ENSG00000169946	ZFPM2	100	92.640	ENSSHAG00000016982	ZFPM2	100	92.550	Sarcophilus_harrisii
ENSG00000169946	ZFPM2	100	52.321	ENSSFOG00015019499	-	100	51.887	Scleropages_formosus
ENSG00000169946	ZFPM2	100	66.797	ENSSFOG00015005974	ZFPM2	98	65.897	Scleropages_formosus
ENSG00000169946	ZFPM2	64	69.697	ENSSFOG00015022860	zfpm1	67	69.697	Scleropages_formosus
ENSG00000169946	ZFPM2	100	63.356	ENSSMAG00000009753	zfpm2a	100	62.521	Scophthalmus_maximus
ENSG00000169946	ZFPM2	66	69.697	ENSSDUG00000003117	zfpm1	80	69.697	Seriola_dumerili
ENSG00000169946	ZFPM2	100	64.210	ENSSDUG00000008509	zfpm2a	97	63.958	Seriola_dumerili
ENSG00000169946	ZFPM2	64	46.479	ENSSLDG00000005129	zfpm1	80	69.697	Seriola_lalandi_dorsalis
ENSG00000169946	ZFPM2	100	64.535	ENSSLDG00000009738	zfpm2a	100	62.688	Seriola_lalandi_dorsalis
ENSG00000169946	ZFPM2	100	100.000	ENSSARG00000009246	ZFPM2	99	87.411	Sorex_araneus
ENSG00000169946	ZFPM2	95	89.414	ENSSPUG00000009479	ZFPM2	100	89.414	Sphenodon_punctatus
ENSG00000169946	ZFPM2	80	75.758	ENSSPUG00000007519	ZFPM1	81	75.758	Sphenodon_punctatus
ENSG00000169946	ZFPM2	100	64.085	ENSSPAG00000019997	zfpm2a	97	63.845	Stegastes_partitus
ENSG00000169946	ZFPM2	76	69.697	ENSSPAG00000020928	zfpm1	79	69.697	Stegastes_partitus
ENSG00000169946	ZFPM2	60	71.429	ENSSSCG00000040875	ZFPM1	75	75.758	Sus_scrofa
ENSG00000169946	ZFPM2	100	100.000	ENSSSCG00000006038	ZFPM2	100	95.569	Sus_scrofa
ENSG00000169946	ZFPM2	100	92.308	ENSTGUG00000012190	ZFPM2	100	90.476	Taeniopygia_guttata
ENSG00000169946	ZFPM2	69	69.697	ENSTRUG00000001306	zfpm1	74	69.697	Takifugu_rubripes
ENSG00000169946	ZFPM2	100	62.655	ENSTRUG00000008754	zfpm2a	99	62.982	Takifugu_rubripes
ENSG00000169946	ZFPM2	91	49.751	ENSTNIG00000008211	zfpm2a	100	50.398	Tetraodon_nigroviridis
ENSG00000169946	ZFPM2	100	100.000	ENSTTRG00000004168	ZFPM2	100	94.961	Tursiops_truncatus
ENSG00000169946	ZFPM2	100	100.000	ENSUAMG00000015158	ZFPM2	100	96.835	Ursus_americanus
ENSG00000169946	ZFPM2	100	100.000	ENSUMAG00000019959	ZFPM2	100	96.439	Ursus_maritimus
ENSG00000169946	ZFPM2	100	96.154	ENSVPAG00000002284	ZFPM2	100	90.980	Vicugna_pacos
ENSG00000169946	ZFPM2	100	100.000	ENSVVUG00000017054	ZFPM2	100	95.739	Vulpes_vulpes
ENSG00000169946	ZFPM2	96	77.561	ENSXETG00000006505	zfpm2	100	77.561	Xenopus_tropicalis
ENSG00000169946	ZFPM2	96	63.300	ENSXCOG00000002552	zfpm2a	98	63.536	Xiphophorus_couchianus
ENSG00000169946	ZFPM2	56	45.455	ENSXCOG00000001883	zfpm1	92	32.016	Xiphophorus_couchianus
ENSG00000169946	ZFPM2	89	32.462	ENSXMAG00000009855	zfpm1	99	35.036	Xiphophorus_maculatus
ENSG00000169946	ZFPM2	100	63.846	ENSXMAG00000003403	zfpm2a	100	62.742	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0001085	RNA polymerase II transcription factor binding	21873635.	IBA	Function
GO:0001570	vasculogenesis	-	IEA	Process
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0003148	outflow tract septum morphogenesis	20807224.	IMP	Process
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	20807224.	IMP	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003713	transcription coactivator activity	10438528.	NAS	Function
GO:0003714	transcription corepressor activity	10438528.	IDA	Function
GO:0005515	protein binding	10438528.19723756.20705609.21220346.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0007506	gonadal mesoderm development	-	IEA	Process
GO:0007507	heart development	21873635.	IBA	Process
GO:0007596	blood coagulation	-	TAS	Process
GO:0008134	transcription factor binding	10438528.	IPI	Function
GO:0008270	zinc ion binding	10438528.	NAS	Function
GO:0030324	lung development	-	IEA	Process
GO:0045599	negative regulation of fat cell differentiation	20705609.	IMP	Process
GO:0045892	negative regulation of transcription, DNA-templated	20206639.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	10438528.	IDA	Process
GO:0048568	embryonic organ development	-	IEA	Process
GO:0060045	positive regulation of cardiac muscle cell proliferation	-	ISS	Process
GO:0060412	ventricular septum morphogenesis	20807224.	IMP	Process
GO:0060548	negative regulation of cell death	-	IEA	Process
GO:2000020	positive regulation of male gonad development	-	IEA	Process
GO:2000195	negative regulation of female gonad development	-	IEA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr8	105802234	Missense_Mutation	novel	L718V	0.49
ACC	chr8	105801661	Nonsense_Mutation	novel	R527*	0.5
ACC	chr8	105802459	Nonsense_Mutation	novel	G793*	0.28
ACC	chr8	105802770	Silent	NA	P896P	0.2
BLCA	chr8	105802606	Missense_Mutation	rs374720145	R842W	0.27
BLCA	chr8	105802956	Missense_Mutation	NA	N958K	0.18
BLCA	chr8	105801176	Missense_Mutation	NA	C365Y	0.11
BLCA	chr8	105801598	Missense_Mutation	novel	D506H	0.06
BLCA	chr8	105788792	Missense_Mutation	novel	D203H	0.09
BLCA	chr8	105801923	Missense_Mutation	NA	A614D	0.14
BLCA	chr8	105561482	Splice_Site	NA	X140_splice	0.58
BLCA	chr8	105801965	Missense_Mutation	NA	S628C	0.32
BLCA	chr8	105802607	Missense_Mutation	rs768561041	R842Q	0.5
BLCA	chr8	105801327	Missense_Mutation	novel	L415F	0.62
BLCA	chr8	105803284	Nonsense_Mutation	novel	Q1068*	0.37
BLCA	chr8	105801330	Silent	novel	T416T	0.4
BLCA	chr8	105801193	Missense_Mutation	rs759870308	G371S	0.19
BLCA	chr8	105803198	Missense_Mutation	rs779563157	R1039Q	0.22
BRCA	chr8	105804339	3'UTR	novel		0.15
BRCA	chr8	105802782	Silent	NA	S900S	0.19
BRCA	chr8	105419202	Silent	novel	D33D	0.06
BRCA	chr8	105801495	Missense_Mutation	NA	K471N	0.64
BRCA	chr8	105803625	3'UTR	novel		0.29
BRCA	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.27
BRCA	chr8	105634290	Missense_Mutation	NA	K155N	0.27
BRCA	chr8	105561422	Missense_Mutation	novel	P121S	0.06
BRCA	chr8	105803286	Silent	NA	Q1068Q	0.21
BRCA	chr8	105419147	Missense_Mutation	NA	P15Q	0.16
BRCA	chr8	105419148	Silent	NA	P15P	0.17
BRCA	chr8	105802148	Missense_Mutation	NA	C689S	0.24
BRCA	chr8	105634325	Missense_Mutation	NA	D167V	0.24
BRCA	chr8	105801664	Missense_Mutation	NA	L528M	0.15
BRCA	chr8	105802948	Nonsense_Mutation	NA	E956*	0.24
BRCA	chr8	105798837	Missense_Mutation	novel	E285K	0.21
BRCA	chr8	105802580	Missense_Mutation	NA	S833T	0.22
BRCA	chr8	105419148	Silent	novel	P15P	0.11
BRCA	chr8	105802911	Silent	rs752360592	K943K	0.31
BRCA	chr8	105803158	Missense_Mutation	novel	A1026T	0.29
BRCA	chr8	105802309	Nonsense_Mutation	NA	E743*	0.11
BRCA	chr8	105419182	Missense_Mutation	NA	C27S	0.36
BRCA	chr8	105801340	Missense_Mutation	novel	L420I	0.04
BRCA	chr8	105803478	Silent	NA	S1132S	0.6
CESC	chr8	105634341	Silent	rs759765008	C172C	0.11
CESC	chr8	105801736	Missense_Mutation	NA	E552Q	0.35
CESC	chr8	105802831	Missense_Mutation	NA	E917K	0.13
CESC	chr8	105803354	Missense_Mutation	rs746420683	S1091L	0.32
CESC	chr8	105801554	Missense_Mutation	NA	S491Y	0.43
CESC	chr8	105804026	3'UTR	novel		0.22
CESC	chr8	105419205	Silent	NA	I34I	0.16
COAD	chr8	105318951	Silent	NA	R4R	0.68
COAD	chr8	105801417	Silent	NA	T445T	0.33
COAD	chr8	105318963	Nonsense_Mutation	NA	K8*	0.13
COAD	chr8	105802598	Missense_Mutation	NA	Q839R	0.13
COAD	chr8	105802940	Missense_Mutation	NA	A953V	0.16
COAD	chr8	105419148	Silent	NA	P15P	0.47
COAD	chr8	105318938	5'UTR	novel		0.17
COAD	chr8	105798777	Missense_Mutation	NA	L265M	0.17
COAD	chr8	105788891	Missense_Mutation	NA	M236V	0.2
COAD	chr8	105801686	Missense_Mutation	novel	Y535C	0.11
COAD	chr8	105802755	Silent	rs567353284	D891D	0.28
COAD	chr8	105802110	Silent	NA	P676P	0.29
COAD	chr8	105801413	Missense_Mutation	NA	K444R	0.44
COAD	chr8	105801737	Frame_Shift_Del	NA	*E552Gfs4**	0.22
COAD	chr8	105788777	Frame_Shift_Del	novel	*F198Lfs15**	0.12
COAD	chr8	105801882	Silent	NA	G600G	0.12
COAD	chr8	105444282	Missense_Mutation	NA	D68N	0.13
COAD	chr8	105803461	Nonsense_Mutation	novel	Q1127*	0.13	zf-met
COAD	chr8	105419232	Missense_Mutation	NA	E43D	0.04
COAD	chr8	105561482	Splice_Site	NA	X140_splice	0.17
COAD	chr8	105561468	Missense_Mutation	novel	N136I	0.04
COAD	chr8	105802695	Silent	novel	A871A	0.14
COAD	chr8	105802391	Missense_Mutation	NA	C770S	0.3
COAD	chr8	105801110	Missense_Mutation	novel	T343I	0.08
COAD	chr8	105802408	Missense_Mutation	NA	P776S	0.13
COAD	chr8	105788912	Missense_Mutation	NA	A243T	0.31
COAD	chr8	105801192	Silent	rs755422326	F370F	0.35
COAD	chr8	105802063	Missense_Mutation	NA	D661N	0.3
COAD	chr8	105798800	Silent	NA	Y272Y	0.28
COAD	chr8	105802616	Missense_Mutation	rs530517993	T845M	0.3
COAD	chr8	105801493	Missense_Mutation	NA	K471Q	0.31
COAD	chr8	105802731	Missense_Mutation	NA	Q883H	0.33
DLBC	chr8	105802835	Missense_Mutation	novel	K918T	0.33
ESCA	chr8	105804171	3'UTR	novel		0.25
ESCA	chr8	105798819	Missense_Mutation	novel	E279K	0.19
ESCA	chr8	105803693	3'UTR	novel		0.14
ESCA	chr8	105801130	Missense_Mutation	novel	F350I	0.08
ESCA	chr8	105803621	3'UTR	novel		0.13
ESCA	chr8	105801112	Missense_Mutation	novel	A344S	0.27
ESCA	chr8	105802612	Missense_Mutation	novel	T844A	0.69
ESCA	chr8	105803885	3'UTR	novel		0.17
ESCA	chr8	105802364	Missense_Mutation	novel	L761P	0.38
ESCA	chr8	105804087	3'UTR	novel		0.41
ESCA	chr8	105803895	3'UTR	novel		0.14
ESCA	chr8	105634247	Missense_Mutation	novel	K141T	0.29
ESCA	chr8	105801107	Missense_Mutation	novel	Y342S	0.16
GBM	chr8	105801336	Silent	rs745380121	S418S	0.34
GBM	chr8	105802755	Silent	rs567353284	D891D	0.4
GBM	chr8	105801610	Missense_Mutation	novel	V510I	0.12
GBM	chr8	105802959	Missense_Mutation	novel	R959S	0.55
GBM	chr8	105803342	Missense_Mutation	novel	N1087I	0.14
GBM	chr8	105801654	Silent	novel	V524V	0.24
GBM	chr8	105801126	Silent	novel	I348I	0.09
HNSC	chr8	105803412	Silent	rs775737083	G1110G	0.52
HNSC	chr8	105803313	Silent	rs775570126	S1077S	0.08
HNSC	chr8	105798928	Missense_Mutation	novel	M315K	0.19
HNSC	chr8	105802402	Nonsense_Mutation	novel	Q774*	0.12
KIRC	chr8	105798857	Silent	rs750690965	A291A	0.19
KIRC	chr8	105634273	Silent	NA	L150L	0.39
KIRC	chr8	105801246	Silent	rs376392532	S388S	0.6
KIRC	chr8	105788840	Missense_Mutation	NA	Y219D	0.27
KIRC	chr8	105801662	Missense_Mutation	NA	R527Q	0.29
KIRC	chr8	105803443	Missense_Mutation	NA	C1121R	0.17	zf-met
KIRC	chr8	105801959	Missense_Mutation	NA	I626S	0.34
KIRC	chr8	105802196	Frame_Shift_Ins	novel	*H705Qfs41**	0.08
KIRC	chr8	105801442	Missense_Mutation	NA	P454T	0.12
KIRC	chr8	105798737	Silent	NA	P251P	0.19
LAML	chr8	105803133	Frame_Shift_Del	novel	*Q1018Rfs10**	0.05
LGG	chr8	105802058	Missense_Mutation	NA	N659S	0.39
LGG	chr8	105802456	Missense_Mutation	rs756871219	P792S	0.42
LIHC	chr8	105801441	Missense_Mutation	NA	R453S	0.11
LIHC	chr8	105801694	Missense_Mutation	rs575054307	V538I	0.97
LIHC	chr8	105801232	Missense_Mutation	novel	L384I	0.47
LIHC	chr8	105801233	Missense_Mutation	novel	L384P	0.46
LIHC	chr8	105802498	Missense_Mutation	NA	N806D	0.52
LIHC	chr8	105798915	Frame_Shift_Del	novel	*R311Efs3**	0.09
LIHC	chr8	105801971	Missense_Mutation	rs756076552	T630I	0.13
LIHC	chr8	105318951	Nonsense_Mutation	NA	R4*	0.15
LIHC	chr8	105318981	Splice_Region	novel	R14R	0.49
LIHC	chr8	105801350	Missense_Mutation	rs377466426	S423N	0.45
LIHC	chr8	105801097	Missense_Mutation	rs201845067	V339I	0.22
LIHC	chr8	105801499	In_Frame_Ins	novel	E473delinsGHFK	0.06
LIHC	chr8	105318981	Missense_Mutation	novel	R14W	0.23
LIHC	chr8	105798895	Missense_Mutation	novel	T304S	0.04
LUAD	chr8	105788857	Silent	NA	L224L	0.38
LUAD	chr8	105801881	Missense_Mutation	NA	G600V	0.52
LUAD	chr8	105801615	Silent	NA	P511P	0.11
LUAD	chr8	105801928	Missense_Mutation	NA	P616A	0.08
LUAD	chr8	105561438	Missense_Mutation	NA	W126L	0.07
LUAD	chr8	105802612	Missense_Mutation	NA	T844S	0.27
LUAD	chr8	105803238	Silent	novel	E1052E	0.07
LUAD	chr8	105801201	Silent	NA	Q373Q	0.2
LUAD	chr8	105801051	Silent	NA	V323V	0.21
LUAD	chr8	105802919	Missense_Mutation	novel	S946I	0.29
LUAD	chr8	105803337	Silent	NA	A1085A	0.09
LUAD	chr8	105801427	Missense_Mutation	NA	L449V	0.07
LUAD	chr8	105802606	Silent	novel	R842R	0.3
LUAD	chr8	105802109	Missense_Mutation	NA	P676L	0.29
LUAD	chr8	105802295	Missense_Mutation	rs780534224	R738L	0.12
LUAD	chr8	105802417	Missense_Mutation	rs376994109	G779R	0.17
LUAD	chr8	105801565	Missense_Mutation	NA	G495C	0.14
LUAD	chr8	105803222	Missense_Mutation	novel	G1047V	0.22
LUAD	chr8	105802678	Missense_Mutation	novel	V866L	0.35
LUAD	chr8	105801256	Missense_Mutation	NA	P392S	0.48
LUAD	chr8	105419152	Missense_Mutation	novel	E17Q	0.25
LUAD	chr8	105801635	Missense_Mutation	NA	A518D	0.31
LUAD	chr8	105801826	Missense_Mutation	rs762467813	P582A	0.26
LUAD	chr8	105801335	Missense_Mutation	novel	S418I	0.13
LUAD	chr8	105801337	Nonsense_Mutation	novel	E419*	0.13
LUAD	chr8	105802062	Missense_Mutation	novel	D660E	0.36
LUAD	chr8	105801436	Nonsense_Mutation	NA	Q452*	0.14
LUAD	chr8	105419148	Silent	novel	P15P	0.23
LUAD	chr8	105419225	Missense_Mutation	NA	P41Q	0.06
LUAD	chr8	105798872	Missense_Mutation	NA	S296R	0.05
LUAD	chr8	105788723	Missense_Mutation	novel	Q180K	0.33
LUAD	chr8	105444365	Missense_Mutation	novel	D95E	0.38
LUAD	chr8	105801636	Silent	novel	A518A	0.21
LUAD	chr8	105802196	Missense_Mutation	NA	H705R	0.34
LUAD	chr8	105561460	Missense_Mutation	NA	M133I	0.15
LUAD	chr8	105788851	Silent	novel	R222R	0.07
LUAD	chr8	105801913	Missense_Mutation	novel	A611S	0.1
LUAD	chr8	105802179	Silent	rs139368368	H699H	0.13
LUAD	chr8	105801066	Missense_Mutation	NA	F328L	0.52
LUAD	chr8	105801816	Missense_Mutation	rs775101596	M578I	0.46
LUAD	chr8	105798791	Missense_Mutation	NA	L269F	0.24
LUAD	chr8	105801058	Missense_Mutation	novel	E326K	0.16
LUAD	chr8	105802403	Missense_Mutation	novel	Q774L	0.43
LUAD	chr8	105802714	Missense_Mutation	novel	P878T	0.2
LUAD	chr8	105802715	Missense_Mutation	novel	P878Q	0.2
LUAD	chr8	105803447	Missense_Mutation	novel	R1122L	0.36	zf-met
LUAD	chr8	105788825	Missense_Mutation	NA	L214F	0.11
LUAD	chr8	105801943	Missense_Mutation	novel	L621I	0.22
LUAD	chr8	105798762	Missense_Mutation	novel	R260W	0.09
LUAD	chr8	105802809	Nonsense_Mutation	novel	Y909*	0.3
LUAD	chr8	105801680	Missense_Mutation	novel	S533I	0.4
LUAD	chr8	105802914	Silent	novel	V944V	0.31
LUAD	chr8	105798791	Missense_Mutation	NA	L269F	0.51
LUAD	chr8	105801551	Missense_Mutation	NA	P490H	0.17
LUAD	chr8	105802366	Missense_Mutation	novel	D762Y	0.29
LUAD	chr8	105803113	Nonsense_Mutation	novel	E1011*	0.22
LUAD	chr8	105801815	Missense_Mutation	novel	M578T	0.32
LUAD	chr8	105802103	Missense_Mutation	novel	S674N	0.51
LUAD	chr8	105801680	Missense_Mutation	NA	S533T	0.2
LUAD	chr8	105803199	Silent	NA	R1039R	0.31
LUAD	chr8	105801929	Missense_Mutation	NA	P616L	0.11
LUAD	chr8	105801455	Missense_Mutation	NA	P458L	0.28
LUAD	chr8	105802043	Missense_Mutation	novel	S654Y	0.2
LUAD	chr8	105444278	Splice_Site	novel	X67_splice	0.06
LUAD	chr8	105801614	Missense_Mutation	novel	P511L	0.16
LUAD	chr8	105803013	Silent	novel	G977G	0.77
LUAD	chr8	105803020	Missense_Mutation	NA	Q980K	0.48
LUAD	chr8	105801950	Missense_Mutation	novel	T623I	0.33
LUAD	chr8	105802324	Nonsense_Mutation	NA	E748*	0.13
LUAD	chr8	105444341	Silent	rs755810063	P87P	0.27
LUAD	chr8	105802895	Missense_Mutation	NA	T938N	0.42
LUAD	chr8	105801337	Missense_Mutation	rs374581095	E419K	0.11
LUAD	chr8	105802272	Missense_Mutation	NA	Q730H	0.12
LUAD	chr8	105419232	Missense_Mutation	NA	E43D	0.22
LUAD	chr8	105802608	Silent	novel	R842R	0.33
LUSC	chr8	105803268	Silent	novel	N1062N	0.47
LUSC	chr8	105803345	Missense_Mutation	novel	E1088V	0.15
LUSC	chr8	105802224	Silent	novel	H714H	0.13
LUSC	chr8	105788840	Missense_Mutation	novel	Y219H	0.71
LUSC	chr8	105798771	Frame_Shift_Del	novel	*R263Gfs7**	0.13
LUSC	chr8	105801193	Missense_Mutation	rs759870308	G371S	0.3
LUSC	chr8	105788747	Missense_Mutation	NA	A188T	0.34
LUSC	chr8	105802822	Missense_Mutation	NA	I914V	0.49
LUSC	chr8	105802573	Missense_Mutation	NA	D831Y	0.13
LUSC	chr8	105803313	Silent	NA	S1077S	0.16
LUSC	chr8	105801459	Silent	novel	T459T	0.07
LUSC	chr8	105444338	Missense_Mutation	NA	K86N	0.77
LUSC	chr8	105788831	Nonsense_Mutation	novel	E216*	0.48
LUSC	chr8	105802580	Missense_Mutation	NA	S833I	0.1
LUSC	chr8	105802174	Silent	rs375403029	R698R	0.13
LUSC	chr8	105634320	Silent	novel	V165V	0.58
LUSC	chr8	105788766	Missense_Mutation	novel	E194G	0.12
LUSC	chr8	105803396	Missense_Mutation	novel	A1105E	0.24
LUSC	chr8	105788857	Silent	NA	L224L	0.14
LUSC	chr8	105801510	Silent	NA	S476S	0.18
LUSC	chr8	105803214	Silent	NA	V1044V	0.35
LUSC	chr8	105444304	Missense_Mutation	novel	T75R	0.14
LUSC	chr8	105801797	Missense_Mutation	novel	S572I	0.36
LUSC	chr8	105802004	Missense_Mutation	novel	G641A	0.16
LUSC	chr8	105802494	Silent	NA	T804T	0.61
LUSC	chr8	105803233	Missense_Mutation	novel	D1051Y	0.26
LUSC	chr8	105803311	Missense_Mutation	novel	S1077T	0.14
LUSC	chr8	105803260	Missense_Mutation	NA	Q1060K	0.37
LUSC	chr8	105801795	Nonsense_Mutation	novel	C571*	0.36
LUSC	chr8	105802286	Missense_Mutation	novel	T735I	0.53
LUSC	chr8	105801772	Missense_Mutation	NA	L564V	0.12
LUSC	chr8	105802132	Missense_Mutation	NA	P684T	0.17
LUSC	chr8	105802174	Silent	rs375403029	R698R	0.35
LUSC	chr8	105419183	Missense_Mutation	novel	C27Y	0.09
LUSC	chr8	105798921	Missense_Mutation	NA	L313I	0.27
LUSC	chr8	105802435	Missense_Mutation	NA	H785N	0.22
LUSC	chr8	105801741	Nonsense_Mutation	novel	C553*	0.25
LUSC	chr8	105802803	Silent	novel	V907V	0.29
LUSC	chr8	105803429	Missense_Mutation	NA	T1116N	0.22
LUSC	chr8	105801515	Missense_Mutation	novel	R478K	0.11
LUSC	chr8	105801550	Missense_Mutation	novel	P490T	0.13
LUSC	chr8	105802029	Missense_Mutation	NA	Q649H	0.38
LUSC	chr8	105419248	Nonsense_Mutation	NA	E49*	0.16
LUSC	chr8	105798764	Silent	NA	R260R	0.23
LUSC	chr8	105801944	Missense_Mutation	novel	L621P	0.23
OV	chr8	105801351	Missense_Mutation	NA	S423R	0.15
OV	chr8	105803479	Frame_Shift_Del	NA	*F1134Sfs18**	0.79	zf-met
OV	chr8	105802408	Missense_Mutation	NA	P776T	0.29
OV	chr8	105802392	Nonsense_Mutation	NA	C770*	0.41
OV	chr8	105444310	Missense_Mutation	NA	E77G	0.16
OV	chr8	105802514	Frame_Shift_Del	NA	S812*	0.3
OV	chr8	105634343	Splice_Site	novel	X174_splice	0.18
OV	chr8	105801064	Missense_Mutation	novel	F328L	0.17
OV	chr8	105801604	Missense_Mutation	novel	T508S	0.11
OV	chr8	105803210	Frame_Shift_Del	novel	*I1043Kfs2**	0.15
OV	chr8	105801621	Silent	novel	A513A	0.06
OV	chr8	105798917	Silent	NA	R311R	0.11
PAAD	chr8	105803544	3'UTR	novel		0.11
PAAD	chr8	105803149	Missense_Mutation	novel	G1023R	0.08
PAAD	chr8	105419220	Missense_Mutation	novel	D39E	0.12
PAAD	chr8	105795803	Intron	novel		0.16
PAAD	chr8	105802228	Missense_Mutation	novel	P716S	0.21
PAAD	chr8	105802786	Nonsense_Mutation	NA	R902*	0.28
PCPG	chr8	105803459	Missense_Mutation	rs757992625	I1126T	0.12	zf-met
PRAD	chr8	105802295	Missense_Mutation	rs780534224	R738H	0.19
PRAD	chr8	105798835	Missense_Mutation	NA	S284L	0.25
PRAD	chr8	105801447	Silent	novel	E455E	0.4
PRAD	chr8	105801192	Silent	rs755422326	F370F	0.05
PRAD	chr8	105801887	Missense_Mutation	NA	T602I	0.08
PRAD	chr8	105802282	Missense_Mutation	rs781567366	R734C	0.07
PRAD	chr8	105801890	Missense_Mutation	novel	S603F	0.45
READ	chr8	105444366	Missense_Mutation	NA	D96N	0.21
READ	chr8	105801707	Missense_Mutation	NA	P542H	0.14
READ	chr8	105802603	Missense_Mutation	NA	E841K	0.12
READ	chr8	105803376	Missense_Mutation	NA	E1098D	0.2
READ	chr8	105802592	Nonsense_Mutation	NA	L837*	0.07
READ	chr8	105801489	Missense_Mutation	NA	K469N	0.12
READ	chr8	105802563	Silent	NA	D827D	0.31
READ	chr8	105802715	Missense_Mutation	rs753602172	P878L	0.18
READ	chr8	105801959	Missense_Mutation	NA	I626N	0.17
READ	chr8	105802289	Missense_Mutation	rs779236742	R736H	0.38
READ	chr8	105802704	Missense_Mutation	NA	Q874H	0.46
READ	chr8	105802833	Silent	NA	E917E	0.33
READ	chr8	105802786	Nonsense_Mutation	NA	R902*	0.52
READ	chr8	105801262	Nonsense_Mutation	NA	E394*	0.42
READ	chr8	105801598	Missense_Mutation	NA	D506Y	0.4
READ	chr8	105801965	Missense_Mutation	rs373978860	S628Y	0.23
READ	chr8	105802573	Missense_Mutation	NA	D831Y	0.37
READ	chr8	105795881	Intron	NA		0.47
SARC	chr8	105802249	Missense_Mutation	novel	S723P	0.22
SARC	chr8	105802250	Missense_Mutation	rs267601701	S723F	0.22
SARC	chr8	105802920	Missense_Mutation	novel	S946R	0.39
SARC	chr8	105802225	Missense_Mutation	NA	D715N	0.22
SARC	chr8	105801461	Missense_Mutation	novel	T460I	0.26
SKCM	chr8	105803559	3'UTR	novel		0.53
SKCM	chr8	105801834	Silent	NA	F584F	0.31
SKCM	chr8	105801965	Missense_Mutation	novel	S628F	0.31
SKCM	chr8	105803219	Missense_Mutation	novel	G1046D	0.36
SKCM	chr8	105801337	Missense_Mutation	rs374581095	E419K	0.21
SKCM	chr8	105803436	Silent	NA	G1118G	0.21
SKCM	chr8	105444346	Missense_Mutation	novel	Q89L	0.41
SKCM	chr8	105803296	Missense_Mutation	rs758582683	D1072N	0.24
SKCM	chr8	105801554	Missense_Mutation	NA	S491F	0.29
SKCM	chr8	105802398	Silent	NA	S772S	0.73
SKCM	chr8	105802880	Missense_Mutation	NA	S933L	0.76
SKCM	chr8	105803290	Missense_Mutation	rs759676967	E1070K	0.27
SKCM	chr8	105801834	Silent	NA	F584F	0.36
SKCM	chr8	105798840	Missense_Mutation	novel	E286K	0.37
SKCM	chr8	105802109	Missense_Mutation	NA	P676L	0.52
SKCM	chr8	105801886	Missense_Mutation	novel	T602A	0.36
SKCM	chr8	105802424	Missense_Mutation	novel	G781E	0.26
SKCM	chr8	105801834	Silent	NA	F584F	0.13
SKCM	chr8	105801690	Silent	novel	P536P	0.18
SKCM	chr8	105802787	Missense_Mutation	NA	R902Q	0.4
SKCM	chr8	105801748	Missense_Mutation	rs374672861	T556A	0.34
SKCM	chr8	105798884	Silent	NA	F300F	0.08
SKCM	chr8	105801721	Missense_Mutation	NA	G547R	0.08
SKCM	chr8	105561396	Missense_Mutation	rs752577785	R112Q	0.09
SKCM	chr8	105802109	Missense_Mutation	NA	P676L	0.54
SKCM	chr8	105802731	Silent	novel	Q883Q	0.24
SKCM	chr8	105803436	Silent	NA	G1118G	0.55
SKCM	chr8	105802494	Silent	NA	T804T	0.5
SKCM	chr8	105801252	Silent	NA	K390K	0.84
SKCM	chr8	105419194	Missense_Mutation	novel	E31K	0.5
SKCM	chr8	105561396	Missense_Mutation	rs752577785	R112Q	0.35
SKCM	chr8	105444282	Missense_Mutation	NA	D68N	0.2
SKCM	chr8	105801704	Missense_Mutation	NA	S541N	0.37
SKCM	chr8	105802076	Missense_Mutation	NA	G665E	0.23
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.3
SKCM	chr8	105802447	Missense_Mutation	NA	D789N	0.31
SKCM	chr8	105802787	Missense_Mutation	NA	R902Q	0.36
SKCM	chr8	105802035	Silent	novel	K651K	0.33
SKCM	chr8	105801274	Missense_Mutation	NA	E398K	0.18
SKCM	chr8	105801865	Missense_Mutation	novel	L595M	0.23
SKCM	chr8	105801834	Silent	NA	F584F	0.19
SKCM	chr8	105801946	Nonsense_Mutation	novel	Q622*	0.19
SKCM	chr8	105802494	Silent	NA	T804T	0.68
SKCM	chr8	105419275	Missense_Mutation	rs780999906	E58K	0.19
SKCM	chr8	105803095	Missense_Mutation	rs747521226	E1005K	0.11
SKCM	chr8	105803402	Missense_Mutation	NA	G1107V	0.24
SKCM	chr8	105798840	Missense_Mutation	novel	E286K	0.19
SKCM	chr8	105802060	Missense_Mutation	novel	D660N	0.3
SKCM	chr8	105803436	Silent	NA	G1118G	0.47
SKCM	chr8	105801072	Silent	novel	P330P	0.54
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.2
SKCM	chr8	105802166	Missense_Mutation	rs757616386	T695I	0.38
SKCM	chr8	105798762	Missense_Mutation	novel	R260W	0.49
SKCM	chr8	105802860	Silent	rs769197775	S926S	0.27
SKCM	chr8	105802695	Silent	NA	A871A	0.3
SKCM	chr8	105802494	Silent	NA	T804T	0.27
SKCM	chr8	105802842	Silent	NA	G920G	0.16
SKCM	chr8	105801066	Silent	NA	F328F	0.61
SKCM	chr8	105802092	Silent	NA	V670V	0.25
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.52
SKCM	chr8	105803316	Nonsense_Mutation	NA	W1078*	0.45
SKCM	chr8	105801144	Silent	NA	L354L	0.35
SKCM	chr8	105801613	Missense_Mutation	NA	P511S	0.2
SKCM	chr8	105801587	Missense_Mutation	NA	S502F	0.21
SKCM	chr8	105802247	Missense_Mutation	NA	A722V	0.21
SKCM	chr8	105803436	Silent	NA	G1118G	0.28
SKCM	chr8	105802547	Missense_Mutation	NA	S822F	0.5
SKCM	chr8	105798840	Missense_Mutation	novel	E286K	0.2
SKCM	chr8	105802880	Missense_Mutation	NA	S933L	0.55
SKCM	chr8	105561449	Missense_Mutation	NA	P130S	0.48
SKCM	chr8	105802517	Missense_Mutation	NA	S812F	0.18
SKCM	chr8	105444376	Missense_Mutation	NA	G99E	0.31
SKCM	chr8	105801473	Missense_Mutation	novel	S464N	0.33
SKCM	chr8	105802239	Silent	rs111634505	K719K	0.63
SKCM	chr8	105798873	Silent	NA	L297L	0.69
SKCM	chr8	105802021	Missense_Mutation	novel	S647T	0.44
SKCM	chr8	105798764	Silent	NA	R260R	0.49
SKCM	chr8	105634285	Missense_Mutation	rs367844776	P154S	0.2
SKCM	chr8	105803029	Missense_Mutation	NA	P983S	0.47
SKCM	chr8	105803259	Silent	NA	Q1059Q	0.26
SKCM	chr8	105795796	Intron	novel		0.29
SKCM	chr8	105798828	Missense_Mutation	NA	P282S	0.52
SKCM	chr8	105802099	Missense_Mutation	NA	P673S	0.54
SKCM	chr8	105801344	Missense_Mutation	NA	P421L	0.15
SKCM	chr8	105634299	Silent	NA	L158L	0.42
SKCM	chr8	105803201	Missense_Mutation	NA	G1040E	0.16
SKCM	chr8	105798773	Silent	novel	R263R	0.11
SKCM	chr8	105802227	Silent	novel	D715D	0.21
SKCM	chr8	105802228	Missense_Mutation	novel	P716S	0.2
SKCM	chr8	105802109	Missense_Mutation	NA	P676L	0.16
SKCM	chr8	105801999	Silent	novel	G639G	0.28
SKCM	chr8	105802092	Silent	NA	V670V	0.64
SKCM	chr8	105801066	Silent	NA	F328F	0.25
SKCM	chr8	105802607	Missense_Mutation	rs768561041	R842Q	0.42
SKCM	chr8	105798873	Silent	NA	L297L	0.13
SKCM	chr8	105788879	Missense_Mutation	NA	Q232K	0.85
SKCM	chr8	105802868	Missense_Mutation	NA	G929E	0.35
SKCM	chr8	105419216	Missense_Mutation	NA	G38E	0.13
SKCM	chr8	105798884	Silent	NA	F300F	0.18
SKCM	chr8	105561396	Missense_Mutation	rs752577785	R112Q	0.48
SKCM	chr8	105803472	Silent	NA	N1130N	0.27
SKCM	chr8	105561396	Missense_Mutation	rs752577785	R112Q	0.46
SKCM	chr8	105798873	Silent	NA	L297L	0.35
SKCM	chr8	105802948	Missense_Mutation	NA	E956K	0.3
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.28
SKCM	chr8	105802387	Missense_Mutation	NA	P769S	0.24
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.15
SKCM	chr8	105802810	Missense_Mutation	rs201981625	E910K	0.14
SKCM	chr8	105788762	Missense_Mutation	NA	E193K	0.35
SKCM	chr8	105802180	Missense_Mutation	rs765404652	E700K	0.36
SKCM	chr8	105803039	Missense_Mutation	NA	G986E	0.48
SKCM	chr8	105802972	Missense_Mutation	NA	P964S	0.17
SKCM	chr8	105803125	Missense_Mutation	NA	P1015S	0.14
SKCM	chr8	105801133	Missense_Mutation	NA	H351Y	0.1
SKCM	chr8	105801603	Silent	NA	I507I	0.11
SKCM	chr8	105801928	Missense_Mutation	NA	P616S	0.07
SKCM	chr8	105801531	Silent	novel	P483P	0.28
SKCM	chr8	105801211	Missense_Mutation	NA	E377K	0.28
SKCM	chr8	105801835	Missense_Mutation	NA	P585S	0.32
SKCM	chr8	105802810	Missense_Mutation	rs201981625	E910K	0.22
SKCM	chr8	105801639	Silent	NA	K519K	0.2
SKCM	chr8	105802831	Missense_Mutation	NA	E917K	0.44
SKCM	chr8	105444342	Missense_Mutation	NA	G88R	0.29
SKCM	chr8	105802170	Silent	novel	F696F	0.27
SKCM	chr8	105801172	Nonsense_Mutation	NA	R364*	0.15
SKCM	chr8	105801357	Silent	rs773287088	K425K	0.1
SKCM	chr8	105801173	Missense_Mutation	NA	R364Q	0.5
SKCM	chr8	105803226	Silent	NA	L1048L	0.42
SKCM	chr8	105444376	Missense_Mutation	NA	G99E	0.41
SKCM	chr8	105802457	Missense_Mutation	NA	P792L	0.5
SKCM	chr8	105561449	Missense_Mutation	NA	P130S	0.33
SKCM	chr8	105444282	Missense_Mutation	NA	D68N	0.32
SKCM	chr8	105561460	Missense_Mutation	NA	M133I	0.16
SKCM	chr8	105801968	Missense_Mutation	NA	S629F	0.37
SKCM	chr8	105802076	Missense_Mutation	NA	G665E	0.3
SKCM	chr8	105419275	Missense_Mutation	rs780999906	E58K	0.52
SKCM	chr8	105561396	Missense_Mutation	rs752577785	R112Q	0.38
SKCM	chr8	105802092	Silent	NA	V670V	0.35
SKCM	chr8	105798880	Missense_Mutation	novel	P299L	0.31
SKCM	chr8	105802810	Missense_Mutation	rs201981625	E910K	0.41
SKCM	chr8	105803365	Missense_Mutation	NA	P1095S	0.46
SKCM	chr8	105802108	Missense_Mutation	novel	P676S	0.43
SKCM	chr8	105802109	Missense_Mutation	NA	P676L	0.42
SKCM	chr8	105802298	Missense_Mutation	NA	R739K	0.36
STAD	chr8	105802625	Missense_Mutation	NA	K848R	0.23
STAD	chr8	105801480	Silent	novel	S466S	0.12
STAD	chr8	105801588	Silent	NA	S502S	0.15
STAD	chr8	105801254	Missense_Mutation	NA	L391R	0.1
STAD	chr8	105803179	Missense_Mutation	novel	P1033S	0.15
STAD	chr8	105802810	Missense_Mutation	rs201981625	E910K	0.22
STAD	chr8	105803226	Silent	NA	L1048L	0.19
STAD	chr8	105802282	Missense_Mutation	rs781567366	R734C	0.12
STAD	chr8	105801417	Silent	NA	T445T	0.27
STAD	chr8	105561438	Frame_Shift_Del	novel	*P128Rfs8**	0.12
STAD	chr8	105801399	Silent	novel	D439D	0.11
STAD	chr8	105801608	Missense_Mutation	NA	M509T	0.06
STAD	chr8	105801226	Missense_Mutation	novel	Q382E	0.07
STAD	chr8	105801326	Missense_Mutation	novel	L415W	0.17
STAD	chr8	105802998	Missense_Mutation	novel	I972M	0.16
STAD	chr8	105802217	Missense_Mutation	novel	T712I	0.23
STAD	chr8	105802693	Missense_Mutation	novel	A871T	0.17
STAD	chr8	105803230	Nonsense_Mutation	NA	Q1050*	0.07
STAD	chr8	105788719	Splice_Region	NA	G178G	0.22
STAD	chr8	105561444	Missense_Mutation	NA	P128L	0.06
STAD	chr8	105788715	Splice_Region	novel		0.08
STAD	chr8	105802901	Missense_Mutation	NA	Q940R	0.17
STAD	chr8	105801480	Silent	NA	S466S	0.18
STAD	chr8	105803178	Silent	NA	L1032L	0.41
STAD	chr8	105561382	Silent	rs761645875	Q107Q	0.09
STAD	chr8	105802176	Silent	NA	R698R	0.29
STAD	chr8	105802836	Silent	NA	K918K	0.24
STAD	chr8	105419148	Silent	novel	P15P	0.22
STAD	chr8	105801658	Missense_Mutation	NA	R526W	0.44
STAD	chr8	105801715	Missense_Mutation	NA	P545S	0.32
STAD	chr8	105801214	Missense_Mutation	NA	L378V	0.09
STAD	chr8	105444341	Silent	rs755810063	P87P	0.13
STAD	chr8	105801413	Missense_Mutation	NA	K444T	0.71
STAD	chr8	105802101	Silent	NA	P673P	0.24
STAD	chr8	105419292	Silent	NA	F63F	0.07
STAD	chr8	105788747	Missense_Mutation	NA	A188T	0.04
STAD	chr8	105801277	Missense_Mutation	rs369889214	H399Y	0.11
STAD	chr8	105801522	Silent	NA	A480A	0.16
STAD	chr8	105802283	Missense_Mutation	rs750762877	R734H	0.08
STAD	chr8	105803114	Frame_Shift_Del	novel	*N1012Mfs16**	0.26
TGCT	chr8	105801492	Silent	novel	I470I	0.22
THCA	chr8	105801128	Missense_Mutation	NA	N349S	0.23
UCEC	chr8	105801085	Missense_Mutation	NA	L335I	0.39
UCEC	chr8	105801658	Missense_Mutation	NA	R526W	0.39
UCEC	chr8	105803444	Missense_Mutation	novel	C1121Y	0.21	zf-met
UCEC	chr8	105803312	Missense_Mutation	NA	S1077L	0.42
UCEC	chr8	105801096	Silent	rs141238169	T338T	0.42
UCEC	chr8	105802969	Missense_Mutation	NA	L963I	0.28
UCEC	chr8	105803423	Missense_Mutation	NA	A1114V	0.3
UCEC	chr8	105801134	Missense_Mutation	novel	H351R	0.39
UCEC	chr8	105802526	Missense_Mutation	novel	D815G	0.12
UCEC	chr8	105804084	3'UTR	novel		0.37
UCEC	chr8	105561477	Missense_Mutation	NA	S139Y	0.29
UCEC	chr8	105444368	Silent	novel	D96D	0.36
UCEC	chr8	105801878	Missense_Mutation	novel	T599I	0.25
UCEC	chr8	105802782	Silent	NA	S900S	0.36
UCEC	chr8	105802782	Silent	NA	S900S	0.5
UCEC	chr8	105801658	Missense_Mutation	NA	R526W	0.17
UCEC	chr8	105802487	Missense_Mutation	rs774419461	S802Y	0.21
UCEC	chr8	105803055	Missense_Mutation	novel	D991E	0.32
UCEC	chr8	105802610	Missense_Mutation	NA	T843M	0.19
UCEC	chr8	105803160	Silent	rs200049316	A1026A	0.54
UCEC	chr8	105419288	Nonsense_Mutation	novel	Y62*	0.08
UCEC	chr8	105798915	Nonsense_Mutation	novel	R311*	0.44
UCEC	chr8	105798734	Missense_Mutation	NA	F250L	0.28
UCEC	chr8	105803414	Missense_Mutation	novel	S1111F	0.15
UCEC	chr8	105803761	3'UTR	novel		0.32
UCEC	chr8	105788727	Missense_Mutation	rs751900535	L181H	0.21
UCEC	chr8	105803734	3'UTR	novel		0.33
UCEC	chr8	105803940	3'UTR	novel		0.48
UCEC	chr8	105804207	3'UTR	novel		0.31
UCEC	chr8	105561478	Silent	novel	S139S	0.11
UCEC	chr8	105634278	Silent	novel	T151T	0.32
UCEC	chr8	105801587	Missense_Mutation	novel	S502Y	0.15
UCEC	chr8	105803502	Missense_Mutation	NA	F1140L	0.33
UCEC	chr8	105804018	3'UTR	rs538440220		0.59
UCEC	chr8	105795815	Intron	novel		0.21
UCEC	chr8	105801677	Missense_Mutation	novel	S532N	0.62
UCEC	chr8	105802793	Missense_Mutation	NA	S904N	0.17
UCEC	chr8	105803616	3'UTR	novel		0.36
UCEC	chr8	105801957	Silent	novel	C625C	0.33
UCEC	chr8	105318951	Nonsense_Mutation	NA	R4*	0.29
UCEC	chr8	105803917	3'UTR	novel		0.29
UCEC	chr8	105801186	Silent	rs754226703	C368C	0.36
UCEC	chr8	105803816	3'UTR	novel		0.4
UCEC	chr8	105801471	Missense_Mutation	novel	Q463H	0.33
UCEC	chr8	105561477	Missense_Mutation	NA	S139Y	0.32
UCEC	chr8	105802997	Missense_Mutation	novel	I972T	0.8
UCEC	chr8	105801454	Missense_Mutation	novel	P458T	0.1
UCEC	chr8	105801455	In_Frame_Ins	novel	P458_T459insVHF	0.09
UCEC	chr8	105801343	Missense_Mutation	novel	P421S	0.5
UCEC	chr8	105802658	Missense_Mutation	NA	C859Y	0.24
UCEC	chr8	105804453	3'UTR	novel		0.15
UCEC	chr8	105419303	Splice_Site	novel	X67_splice	0.11
UCEC	chr8	105419146	Missense_Mutation	novel	P15S	0.35
UCEC	chr8	105801454	Missense_Mutation	novel	P458T	0.07
UCEC	chr8	105801455	Frame_Shift_Ins	novel	*T459Vfs6**	0.07
UCEC	chr8	105801943	Missense_Mutation	novel	L621I	0.44
UCEC	chr8	105803133	Silent	novel	G1017G	0.26
UCEC	chr8	105634246	Missense_Mutation	novel	K141Q	0.38
UCEC	chr8	105801471	Silent	novel	Q463Q	0.31
UCEC	chr8	105802282	Missense_Mutation	rs781567366	R734C	0.37
UCEC	chr8	105802608	Silent	novel	R842R	0.26
UCEC	chr8	105802931	Missense_Mutation	novel	Q950L	0.22
UCEC	chr8	105803455	Missense_Mutation	NA	D1125H	0.17	zf-met
UCEC	chr8	105802477	Missense_Mutation	novel	L799V	0.26
UCEC	chr8	105803501	Missense_Mutation	novel	F1140C	0.3
UCEC	chr8	105801378	Silent	rs376236997	A432A	0.3
UCEC	chr8	105803524	Nonsense_Mutation	novel	E1148*	0.23
UCEC	chr8	105803069	Missense_Mutation	NA	S996Y	0.19
UCEC	chr8	105804207	3'UTR	novel		0.15
UCEC	chr8	105801857	Missense_Mutation	novel	P592L	0.3
UCEC	chr8	105803669	3'UTR	novel		0.22
UCEC	chr8	105802282	Missense_Mutation	rs781567366	R734C	0.38
UCEC	chr8	105561391	Silent	novel	G110G	0.28
UCEC	chr8	105802514	Frame_Shift_Ins	novel	*S812Ifs15**	0.05
UCEC	chr8	105803295	Silent	rs752938527	D1071D	0.27
UCEC	chr8	105802532	Missense_Mutation	NA	T817N	0.35
UCEC	chr8	105803502	Missense_Mutation	NA	F1140L	0.41
UCEC	chr8	105803069	Missense_Mutation	NA	S996Y	0.29
UCEC	chr8	105561477	Missense_Mutation	NA	S139Y	0.21
UCEC	chr8	105788811	Missense_Mutation	NA	A209V	0.31
UCEC	chr8	105802395	Silent	NA	T771T	0.34
UCEC	chr8	105801943	Missense_Mutation	novel	L621I	0.28
UCEC	chr8	105802282	Missense_Mutation	rs781567366	R734C	0.4
UCEC	chr8	105803174	Missense_Mutation	novel	S1031Y	0.08
UCEC	chr8	105419274	Silent	rs549937007	C57C	0.22
UCEC	chr8	105798878	Silent	NA	C298C	0.14
UCEC	chr8	105802489	Silent	rs767693837	L803L	0.33
UCEC	chr8	105803296	Missense_Mutation	rs758582683	D1072N	0.39
UCEC	chr8	105798841	Missense_Mutation	novel	E286G	0.54
UCEC	chr8	105561443	Missense_Mutation	novel	P128S	0.28
UCEC	chr8	105634345	Missense_Mutation	novel	V174M	0.07
UCEC	chr8	105803131	Missense_Mutation	NA	G1017C	0.26
UCEC	chr8	105801336	Silent	rs745380121	S418S	0.4
UCEC	chr8	105804331	3'UTR	novel		0.1
UCEC	chr8	105801568	Missense_Mutation	novel	P496S	0.34
UCEC	chr8	105802796	Missense_Mutation	novel	P905L	0.47
UCS	chr8	105801968	Missense_Mutation	NA	S629F	0.26
UCS	chr8	105802824	Frame_Shift_Del	novel	*K915Nfs8**	0.67
UCS	chr8	105798846	Nonsense_Mutation	novel	E288*	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	AMP	0.1061	0.15559
PRAD	AMP	0.2663	3.7005e-05
SARC	AMP	0.2763	0.18425
TGCT	AMP	0.64	0.13696
THCA	DEL	0.01	0.038162

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.027	Kaplan-Meier Survival Analysis
STAD	0.00039	Kaplan-Meier Survival Analysis
SARC	0.024	Kaplan-Meier Survival Analysis
MESO	0.018	Kaplan-Meier Survival Analysis
LUSC	0.0022	Kaplan-Meier Survival Analysis
ESCA	0.0097	Kaplan-Meier Survival Analysis
KIRP	0.00055	Kaplan-Meier Survival Analysis
COAD	0.035	Kaplan-Meier Survival Analysis
BLCA	0.038	Kaplan-Meier Survival Analysis
LAML	0.00051	Kaplan-Meier Survival Analysis
UCEC	0.017	Kaplan-Meier Survival Analysis
THCA	0.0004	Kaplan-Meier Survival Analysis
UVM	0.0028	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742