EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171115 (Gene tree)
Gene ID: 155038
Gene Symbol: GIMAP8
Alias: DKFZp667I133|hIAN6|IAN9
Full Name: GTPase, IMAP family member 8
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 28,766 bases
Position: chr7:150,450,630-150,479,395
Accession: 21792
RBP type: canonical RBP
Summary: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000305107	MMR_HSR1	PF01926.23	3.7e-20	1	2
ENSP00000305107	MMR_HSR1	PF01926.23	3.7e-20	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000307271	GIMAP8-201	4184	XM_005249950	ENSP00000305107	665 (aa)	XP_005250007	Q8ND71

Gene Model

Click here to download ENSG00000171115's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000171115	Prostatic Neoplasms	2.0480000E-005	18264096
ENSG00000171115	Prostatic Neoplasms	1.5100000E-005	18264096
ENSG00000171115	Blood Pressure	3.1290785E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171115's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171115	GIMAP8	99	61.667	ENSAMEG00000002432	GIMAP8	99	61.667	Ailuropoda_melanoleuca
ENSG00000171115	GIMAP8	99	81.024	ENSANAG00000038300	GIMAP8	97	81.024	Aotus_nancymaae
ENSG00000171115	GIMAP8	99	56.781	ENSBTAG00000014402	GIMAP8	94	56.567	Bos_taurus
ENSG00000171115	GIMAP8	99	81.175	ENSCJAG00000010511	GIMAP8	99	81.175	Callithrix_jacchus
ENSG00000171115	GIMAP8	99	59.970	ENSCAFG00000004572	GIMAP8	99	59.970	Canis_familiaris
ENSG00000171115	GIMAP8	99	60.152	ENSCAFG00020006503	GIMAP8	99	60.152	Canis_lupus_dingo
ENSG00000171115	GIMAP8	98	56.818	ENSCHIG00000013015	-	99	56.515	Capra_hircus
ENSG00000171115	GIMAP8	99	56.818	ENSCHIG00000021733	-	99	56.515	Capra_hircus
ENSG00000171115	GIMAP8	96	46.226	ENSCHIG00000016726	-	96	46.226	Capra_hircus
ENSG00000171115	GIMAP8	99	73.343	ENSTSYG00000014287	GIMAP8	99	73.343	Carlito_syrichta
ENSG00000171115	GIMAP8	99	81.627	ENSCCAG00000022092	GIMAP8	99	81.627	Cebus_capucinus
ENSG00000171115	GIMAP8	98	89.587	ENSCATG00000013026	GIMAP8	99	89.545	Cercocebus_atys
ENSG00000171115	GIMAP8	98	89.127	ENSCSAG00000006880	GIMAP8	99	89.091	Chlorocebus_sabaeus
ENSG00000171115	GIMAP8	98	90.352	ENSCANG00000039247	GIMAP8	99	90.303	Colobus_angolensis_palliatus
ENSG00000171115	GIMAP8	97	56.044	ENSCGRG00001018061	Gimap8	96	56.240	Cricetulus_griseus_chok1gshd
ENSG00000171115	GIMAP8	97	56.044	ENSCGRG00000014281	Gimap8	96	56.240	Cricetulus_griseus_crigri
ENSG00000171115	GIMAP8	99	63.952	ENSEASG00005020627	GIMAP8	95	63.952	Equus_asinus_asinus
ENSG00000171115	GIMAP8	99	64.103	ENSECAG00000018802	GIMAP8	97	65.152	Equus_caballus
ENSG00000171115	GIMAP8	96	50.158	ENSEEUG00000000919	-	96	58.088	Erinaceus_europaeus
ENSG00000171115	GIMAP8	97	63.863	ENSFCAG00000011441	GIMAP8	99	63.863	Felis_catus
ENSG00000171115	GIMAP8	99	45.824	ENSFDAG00000007805	-	97	45.824	Fukomys_damarensis
ENSG00000171115	GIMAP8	100	98.496	ENSGGOG00000025687	GIMAP8	100	98.496	Gorilla_gorilla
ENSG00000171115	GIMAP8	94	62.898	ENSSTOG00000025007	GIMAP8	93	62.898	Ictidomys_tridecemlineatus
ENSG00000171115	GIMAP8	98	89.587	ENSMFAG00000002026	GIMAP8	99	89.545	Macaca_fascicularis
ENSG00000171115	GIMAP8	98	89.587	ENSMMUG00000022636	GIMAP8	99	89.545	Macaca_mulatta
ENSG00000171115	GIMAP8	98	89.433	ENSMNEG00000042139	GIMAP8	99	89.394	Macaca_nemestrina
ENSG00000171115	GIMAP8	98	64.965	ENSMLEG00000036169	GIMAP8	99	65.068	Mandrillus_leucophaeus
ENSG00000171115	GIMAP8	94	34.509	ENSMGAG00000001590	-	100	34.509	Meleagris_gallopavo
ENSG00000171115	GIMAP8	99	67.020	ENSMICG00000015448	GIMAP8	95	67.020	Microcebus_murinus
ENSG00000171115	GIMAP8	97	55.205	ENSMOCG00000005505	Gimap8	96	55.435	Microtus_ochrogaster
ENSG00000171115	GIMAP8	93	56.774	MGP_CAROLIEiJ_G0028347	Gimap8	90	56.774	Mus_caroli
ENSG00000171115	GIMAP8	93	57.097	ENSMUSG00000064262	Gimap8	95	57.097	Mus_musculus
ENSG00000171115	GIMAP8	93	56.613	MGP_PahariEiJ_G0022101	Gimap8	92	56.613	Mus_pahari
ENSG00000171115	GIMAP8	93	57.258	MGP_SPRETEiJ_G0029350	Gimap8	95	57.258	Mus_spretus
ENSG00000171115	GIMAP8	95	59.455	ENSMLUG00000012405	GIMAP8	99	59.455	Myotis_lucifugus
ENSG00000171115	GIMAP8	100	93.985	ENSNLEG00000003821	GIMAP8	100	93.985	Nomascus_leucogenys
ENSG00000171115	GIMAP8	97	48.837	ENSMEUG00000010750	-	99	48.837	Notamacropus_eugenii
ENSG00000171115	GIMAP8	95	36.321	ENSONIG00000005027	GIMAP8	98	36.321	Oreochromis_niloticus
ENSG00000171115	GIMAP8	99	66.516	ENSOCUG00000001150	GIMAP8	96	66.516	Oryctolagus_cuniculus
ENSG00000171115	GIMAP8	99	65.237	ENSOGAG00000030330	GIMAP8	99	65.237	Otolemur_garnettii
ENSG00000171115	GIMAP8	91	58.491	ENSOARG00000001131	-	89	57.547	Ovis_aries
ENSG00000171115	GIMAP8	94	50.253	ENSOARG00000001393	-	100	50.253	Ovis_aries
ENSG00000171115	GIMAP8	100	98.947	ENSPPAG00000038601	GIMAP8	100	98.947	Pan_paniscus
ENSG00000171115	GIMAP8	97	63.297	ENSPPRG00000020196	GIMAP8	99	63.297	Panthera_pardus
ENSG00000171115	GIMAP8	97	63.453	ENSPTIG00000009369	GIMAP8	99	63.453	Panthera_tigris_altaica
ENSG00000171115	GIMAP8	100	99.098	ENSPTRG00000019856	GIMAP8	100	99.098	Pan_troglodytes
ENSG00000171115	GIMAP8	100	98.947	ENSPTRG00000046210	-	100	98.947	Pan_troglodytes
ENSG00000171115	GIMAP8	98	89.127	ENSPANG00000008718	GIMAP8	99	89.091	Papio_anubis
ENSG00000171115	GIMAP8	94	55.377	ENSPEMG00000016086	Gimap8	93	55.377	Peromyscus_maniculatus_bairdii
ENSG00000171115	GIMAP8	100	89.970	ENSPPYG00000018169	GIMAP8	100	89.970	Pongo_abelii
ENSG00000171115	GIMAP8	99	70.953	ENSPCOG00000015779	GIMAP8	95	70.953	Propithecus_coquereli
ENSG00000171115	GIMAP8	98	54.128	ENSPVAG00000010750	GIMAP8	99	54.128	Pteropus_vampyrus
ENSG00000171115	GIMAP8	96	57.416	ENSRNOG00000020169	Gimap8	96	57.416	Rattus_norvegicus
ENSG00000171115	GIMAP8	98	90.505	ENSRBIG00000017674	GIMAP8	100	90.260	Rhinopithecus_bieti
ENSG00000171115	GIMAP8	98	90.658	ENSRROG00000040860	GIMAP8	99	90.606	Rhinopithecus_roxellana
ENSG00000171115	GIMAP8	99	79.970	ENSSBOG00000028699	GIMAP8	99	79.970	Saimiri_boliviensis_boliviensis
ENSG00000171115	GIMAP8	99	43.639	ENSSHAG00000005895	-	99	43.639	Sarcophilus_harrisii
ENSG00000171115	GIMAP8	96	44.512	ENSSHAG00000008260	-	98	44.512	Sarcophilus_harrisii
ENSG00000171115	GIMAP8	93	36.158	ENSSFOG00015007812	-	94	36.158	Scleropages_formosus
ENSG00000171115	GIMAP8	97	50.000	ENSSARG00000004013	-	98	50.000	Sorex_araneus
ENSG00000171115	GIMAP8	97	60.093	ENSSSCG00000016452	GIMAP8	95	60.093	Sus_scrofa
ENSG00000171115	GIMAP8	99	57.381	ENSTBEG00000009953	-	98	57.381	Tupaia_belangeri
ENSG00000171115	GIMAP8	98	61.137	ENSTTRG00000002323	GIMAP8	99	61.178	Tursiops_truncatus
ENSG00000171115	GIMAP8	99	61.364	ENSUAMG00000023316	GIMAP8	99	61.364	Ursus_americanus
ENSG00000171115	GIMAP8	98	61.832	ENSUMAG00000011031	GIMAP8	99	61.832	Ursus_maritimus
ENSG00000171115	GIMAP8	94	61.589	ENSVPAG00000007363	-	99	61.589	Vicugna_pacos
ENSG00000171115	GIMAP8	99	59.841	ENSVVUG00000009161	GIMAP8	99	59.841	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005525	GTP binding	21873635.	IBA	Function
GO:0005739	mitochondrion	-	IEA	Component
GO:0005783	endoplasmic reticulum	-	IEA	Component
GO:0005794	Golgi apparatus	-	IEA	Component
GO:0005829	cytosol	-	IEA	Component
GO:0070232	regulation of T cell apoptotic process	-	IEA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr7	150477247	Missense_Mutation	novel	V489M	0.42	MMR_HSR1
ACC	chr7	150466683	5'UTR	rs767299597		0.45
BLCA	chr7	150466710	Missense_Mutation	novel	Q4H	0.2
BLCA	chr7	150477544	Missense_Mutation	rs770094053	R588W	0.41
BLCA	chr7	150466740	Silent	novel	L14L	0.31
BLCA	chr7	150474024	Missense_Mutation	NA	R232K	0.08
BLCA	chr7	150474521	Missense_Mutation	NA	A398T	0.17
BLCA	chr7	150474218	Nonsense_Mutation	novel	K297*	0.35
BLCA	chr7	150467310	Silent	NA	F204F	0.17
BLCA	chr7	150477453	Silent	rs557029400	T557T	0.15
BLCA	chr7	150477527	Missense_Mutation	NA	S582L	0.25
BLCA	chr7	150467034	Missense_Mutation	novel	E112D	0.5
BRCA	chr7	150477700	Missense_Mutation	NA	V640I	0.19
BRCA	chr7	150477309	Silent	novel	R509R	0.3
BRCA	chr7	150474482	Missense_Mutation	NA	L385V	0.14
BRCA	chr7	150474424	Silent	novel	R365R	0.08
BRCA	chr7	150467117	Missense_Mutation	novel	G140V	0.19
BRCA	chr7	150474053	Missense_Mutation	NA	N242Y	0.1
BRCA	chr7	150474249	Missense_Mutation	NA	S307L	0.17
BRCA	chr7	150467314	Missense_Mutation	NA	T206A	0.26
BRCA	chr7	150474249	Nonsense_Mutation	NA	S307*	0.17
BRCA	chr7	150477893	3'UTR	novel		0.5
BRCA	chr7	150467270	Missense_Mutation	NA	S191Y	0.11
BRCA	chr7	150477734	Missense_Mutation	NA	S651F	0.27
BRCA	chr7	150474047	Missense_Mutation	rs759454503	E240K	0.22
BRCA	chr7	150477840	3'UTR	novel		0.08
CESC	chr7	150474398	Missense_Mutation	NA	E357Q	0.09
CESC	chr7	150474249	Nonsense_Mutation	rs747459758	S307*	0.14
CESC	chr7	150477733	Frame_Shift_Del	novel	*S651Pfs10**	0.12
CESC	chr7	150466760	Missense_Mutation	novel	S21L	0.5
CESC	chr7	150466722	Missense_Mutation	rs372078848	M8I	0.18
CESC	chr7	150477108	Silent	novel	V442V	0.58
CHOL	chr7	150477317	Frame_Shift_Ins	novel	*E512Dfs11**	0.43	MMR_HSR1
CHOL	chr7	150477318	Frame_Shift_Ins	novel	*E513Rfs10**	0.43	MMR_HSR1
COAD	chr7	150477675	Silent	rs768595309	S631S	0.33
COAD	chr7	150474420	Missense_Mutation	NA	T364N	0.14
COAD	chr7	150477522	Missense_Mutation	novel	K580N	0.36
COAD	chr7	150467258	Missense_Mutation	rs200592029	R187H	0.35
COAD	chr7	150466990	Missense_Mutation	novel	L98F	0.19
COAD	chr7	150467010	Silent	NA	G104G	0.33
COAD	chr7	150477674	Missense_Mutation	rs749134661	S631F	0.1
COAD	chr7	150474241	Silent	rs768970689	P304P	0.33
COAD	chr7	150466726	Missense_Mutation	rs143529569	E10K	0.32
COAD	chr7	150474339	Missense_Mutation	novel	T337S	0.12
COAD	chr7	150467191	Missense_Mutation	NA	Y165H	0.28
COAD	chr7	150477462	Silent	NA	A560A	0.21
COAD	chr7	150474106	Frame_Shift_Del	novel	*S261Vfs22**	0.25
COAD	chr7	150474457	Silent	rs547695733	T376T	0.22
COAD	chr7	150477547	Missense_Mutation	rs139453539	R589C	0.26
COAD	chr7	150477551	Frame_Shift_Del	novel	*F591Lfs24**	0.17
COAD	chr7	150466780	Missense_Mutation	NA	N28D	0.27
COAD	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.09
COAD	chr7	150467000	Missense_Mutation	novel	I101S	0.43
COAD	chr7	150474126	Missense_Mutation	NA	S266N	0.24
COAD	chr7	150474347	Missense_Mutation	novel	D340N	0.29
COAD	chr7	150467283	Silent	NA	T195T	0.23
COAD	chr7	150474068	Nonsense_Mutation	NA	E247*	0.07
COAD	chr7	150477511	Missense_Mutation	NA	D577Y	0.11
COAD	chr7	150467143	Frame_Shift_Ins	rs746795576	*N151Kfs12**	0.36
COAD	chr7	150474152	Frame_Shift_Ins	novel	*T275Sfs6**	0.06
COAD	chr7	150474252	Missense_Mutation	NA	S308C	0.28
COAD	chr7	150474316	Silent	NA	L329L	0.43
COAD	chr7	150477329	Missense_Mutation	rs758582699	R516H	0.05	MMR_HSR1
COAD	chr7	150474075	Missense_Mutation	novel	T249K	0.11
ESCA	chr7	150477462	Silent	NA	A560A	0.4
ESCA	chr7	150466686	5'UTR	novel		0.12
GBM	chr7	150474135	Missense_Mutation	novel	G269V	0.04
GBM	chr7	150474464	Silent	novel	R379R	0.04
GBM	chr7	150477840	3'UTR	novel		0.3
GBM	chr7	150474241	Silent	rs768970689	P304P	0.2
GBM	chr7	150467283	Silent	NA	T195T	0.39
GBM	chr7	150474310	Silent	novel	F327F	0.18
GBM	chr7	150477839	3'UTR	rs560046482		0.25
GBM	chr7	150477569	Missense_Mutation	rs139733638	R596Q	0.2
GBM	chr7	150474407	Missense_Mutation	NA	I360V	0.26
GBM	chr7	150477330	Frame_Shift_Ins	novel	*C517Ifs55**	0.04	MMR_HSR1
HNSC	chr7	150474296	Missense_Mutation	NA	G323S	0.12
HNSC	chr7	150466725	Silent	rs370191374	S9S	0.33
HNSC	chr7	150474058	Silent	rs762955793	P243P	0.3
HNSC	chr7	150467211	Silent	novel	K171K	0.05
HNSC	chr7	150477547	Missense_Mutation	rs139453539	R589C	0.15
HNSC	chr7	150466913	Missense_Mutation	rs780657422	S72L	0.15
HNSC	chr7	150477654	Silent	novel	L624L	0.2
HNSC	chr7	150467253	Silent	NA	L185L	0.18
KICH	chr7	150474095	Missense_Mutation	rs576578780	R256C	0.1
KIRC	chr7	150474521	Missense_Mutation	novel	A398P	0.25
KIRC	chr7	150477156	Silent	NA	I458I	0.4
KIRC	chr7	150467102	Missense_Mutation	rs761170315	R135Q	0.23
KIRP	chr7	150474229	Silent	novel	I300I	0.26
LAML	chr7	150466816	Missense_Mutation	novel	F40I	0.04
LGG	chr7	150477448	Frame_Shift_Del	novel	*F556Yfs28**	0.18
LGG	chr7	150477167	Missense_Mutation	novel	L462P	0.1	MMR_HSR1
LGG	chr7	150477676	Missense_Mutation	rs144516226	G632R	0.23
LGG	chr7	150474095	Missense_Mutation	rs576578780	R256C	0.22
LIHC	chr7	150467179	Missense_Mutation	NA	Y161N	0.25
LIHC	chr7	150477997	3'UTR	novel		0.63
LIHC	chr7	150474260	Missense_Mutation	NA	N311D	0.25
LIHC	chr7	150474242	Missense_Mutation	NA	D305Y	0.54
LUAD	chr7	150477734	Missense_Mutation	NA	S651F	0.2
LUAD	chr7	150467116	Missense_Mutation	NA	G140W	0.23
LUAD	chr7	150466737	Silent	NA	L13L	0.3
LUAD	chr7	150477693	Missense_Mutation	novel	Q637H	0.3
LUAD	chr7	150466952	Missense_Mutation	novel	H85R	0.23
LUAD	chr7	150477160	Missense_Mutation	NA	G460W	0.33	MMR_HSR1
LUAD	chr7	150474565	Silent	rs149276246	A412A	0.11
LUAD	chr7	150477334	Silent	novel	L518L	0.5
LUAD	chr7	150477723	Silent	novel	V647V	0.11
LUAD	chr7	150467128	Missense_Mutation	novel	L144M	0.07
LUAD	chr7	150474328	Silent	NA	L333L	0.32
LUAD	chr7	150474206	Missense_Mutation	NA	W293R	0.12
LUAD	chr7	150474315	Missense_Mutation	novel	L329Q	0.34
LUAD	chr7	150477089	Splice_Region	novel		0.52
LUAD	chr7	150474097	Silent	rs772655799	R256R	0.24
LUAD	chr7	150466903	Missense_Mutation	NA	L69I	0.05
LUAD	chr7	150467264	Missense_Mutation	NA	V189A	0.1
LUAD	chr7	150477964	3'UTR	novel		0.5
LUAD	chr7	150477426	Silent	novel	L548L	0.26
LUAD	chr7	150477253	Missense_Mutation	novel	V491I	0.43	MMR_HSR1
LUAD	chr7	150477141	Silent	novel	A453A	0.06
LUAD	chr7	150467258	Missense_Mutation	rs200592029	R187L	0.34
LUAD	chr7	150474249	Missense_Mutation	NA	S307L	0.51
LUAD	chr7	150470874	Missense_Mutation	NA	G228C	0.12
LUAD	chr7	150477375	Silent	NA	V531V	0.32
LUAD	chr7	150477329	Missense_Mutation	NA	R516L	0.29	MMR_HSR1
LUSC	chr7	150470874	Missense_Mutation	NA	G228R	0.46
LUSC	chr7	150474098	Missense_Mutation	novel	G257R	0.07
LUSC	chr7	150477543	Silent	NA	L587L	0.31
LUSC	chr7	150477439	Missense_Mutation	NA	G553R	0.22
LUSC	chr7	150467289	Silent	NA	G197G	0.32
LUSC	chr7	150477628	Missense_Mutation	novel	A616T	0.26
LUSC	chr7	150466940	Missense_Mutation	rs772996358	R81H	0.18
LUSC	chr7	150466829	Missense_Mutation	novel	T44R	0.26
LUSC	chr7	150474206	Missense_Mutation	NA	W293R	0.31
LUSC	chr7	150477571	Nonsense_Mutation	rs200127471	R597*	0.28
LUSC	chr7	150477105	Silent	NA	I441I	0.38
LUSC	chr7	150477196	Missense_Mutation	novel	P472T	0.48	MMR_HSR1
LUSC	chr7	150474424	Missense_Mutation	NA	R365S	0.34
LUSC	chr7	150467057	Missense_Mutation	NA	V120G	0.16
LUSC	chr7	150477452	Missense_Mutation	rs148200096	T557R	0.23
LUSC	chr7	150466722	Missense_Mutation	rs372078848	M8I	0.17
LUSC	chr7	150474594	Missense_Mutation	novel	M422T	0.17
OV	chr7	150477141	Silent	rs376371559	A453A	0.24
OV	chr7	150477911	3'UTR	novel		0.45
OV	chr7	150477345	Frame_Shift_Del	novel	*C521Wfs50**	0.06	MMR_HSR1
OV	chr7	150467001	Silent	novel	I101I	0.18
OV	chr7	150466929	Silent	novel	E77E	0.03
OV	chr7	150474570	Missense_Mutation	novel	E414V	0.07
OV	chr7	150474079	Silent	novel	V250V	0.15
OV	chr7	150477110	Missense_Mutation	novel	L443P	0.06	MMR_HSR1
OV	chr7	150474457	Silent	rs547695733	T376T	0.15
OV	chr7	150477459	Silent	NA	Y559Y	0.07
PAAD	chr7	150474565	Silent	rs149276246	A412A	0.16
PAAD	chr7	150477613	Missense_Mutation	novel	E611K	0.17
PRAD	chr7	150477459	Silent	NA	Y559Y	0.06
PRAD	chr7	150477579	Missense_Mutation	NA	C599W	0.33
READ	chr7	150477420	Silent	NA	A546A	0.46
READ	chr7	150477193	Missense_Mutation	NA	Q471K	0.26	MMR_HSR1
READ	chr7	150467189	Missense_Mutation	rs756123094	R164Q	0.36
READ	chr7	150477329	Missense_Mutation	rs758582699	R516H	0.04	MMR_HSR1
SARC	chr7	150477714	Missense_Mutation	novel	I644M	0.3
SARC	chr7	150477459	Silent	NA	Y559Y	0.22
SARC	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.4
SARC	chr7	150477459	Silent	NA	Y559Y	0.22
SARC	chr7	150477452	Missense_Mutation	novel	T557M	0.58
SARC	chr7	150477392	Missense_Mutation	novel	F537Y	0.12	MMR_HSR1
SKCM	chr7	150477389	Missense_Mutation	NA	R536Q	0.49	MMR_HSR1
SKCM	chr7	150467295	Silent	rs761270896	P199P	0.39
SKCM	chr7	150474058	Silent	rs762955793	P243P	0.28
SKCM	chr7	150477649	Missense_Mutation	NA	D623N	0.35
SKCM	chr7	150477453	Silent	rs557029400	T557T	0.42
SKCM	chr7	150466762	Missense_Mutation	novel	G22R	0.19
SKCM	chr7	150466763	Missense_Mutation	NA	G22E	0.17
SKCM	chr7	150474156	Missense_Mutation	NA	G276E	0.12
SKCM	chr7	150467287	Missense_Mutation	rs147231393	G197R	0.25
SKCM	chr7	150474465	Missense_Mutation	NA	R379K	0.17
SKCM	chr7	150477147	Silent	NA	G455G	0.15
SKCM	chr7	150467294	Missense_Mutation	NA	P199L	0.29
SKCM	chr7	150466812	Silent	NA	S38S	0.11
SKCM	chr7	150477269	Missense_Mutation	rs753699589	S496F	0.18	MMR_HSR1
SKCM	chr7	150474347	Missense_Mutation	novel	D340N	0.66
SKCM	chr7	150474569	Missense_Mutation	rs771833252	E414K	0.24
SKCM	chr7	150474446	Missense_Mutation	NA	D373N	0.44
SKCM	chr7	150474120	Missense_Mutation	novel	G264E	0.19
SKCM	chr7	150474215	Missense_Mutation	novel	K296Q	0.3
SKCM	chr7	150477346	Missense_Mutation	novel	E522K	0.27	MMR_HSR1
SKCM	chr7	150477501	Silent	rs758864006	G573G	0.2
SKCM	chr7	150467283	Silent	NA	T195T	0.34
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.23
SKCM	chr7	150467189	Missense_Mutation	rs756123094	R164Q	0.38
SKCM	chr7	150474428	Missense_Mutation	NA	E367K	0.41
SKCM	chr7	150477631	Missense_Mutation	NA	L617F	0.43
SKCM	chr7	150466822	Missense_Mutation	NA	D42N	0.35
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.16
SKCM	chr7	150466981	Missense_Mutation	NA	H95Y	0.44
SKCM	chr7	150477484	Missense_Mutation	NA	E568K	0.33
SKCM	chr7	150474091	Silent	NA	G254G	0.16
SKCM	chr7	150477608	Missense_Mutation	NA	A609V	0.12
SKCM	chr7	150474610	Silent	NA	G427G	0.15
SKCM	chr7	150474639	Splice_Site	NA	X437_splice	0.47
SKCM	chr7	150467016	Silent	NA	F106F	0.47
SKCM	chr7	150474543	Missense_Mutation	NA	G405E	0.43
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.47
SKCM	chr7	150477171	Silent	NA	V463V	0.4
SKCM	chr7	150477440	Missense_Mutation	NA	G553E	0.28
SKCM	chr7	150474553	Silent	NA	E408E	0.39
SKCM	chr7	150477378	Silent	rs140854559	F532F	0.42
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.08
SKCM	chr7	150474440	Missense_Mutation	NA	D371N	0.36
SKCM	chr7	150477297	Silent	NA	K505K	0.42
SKCM	chr7	150477649	Missense_Mutation	NA	D623N	0.05
SKCM	chr7	150477806	3'UTR	novel		0.17
SKCM	chr7	150477453	Silent	rs557029400	T557T	0.22
SKCM	chr7	150477462	Silent	NA	A560A	0.58
SKCM	chr7	150466741	Missense_Mutation	NA	L15F	0.19
SKCM	chr7	150467139	Silent	NA	F147F	0.49
SKCM	chr7	150474024	Missense_Mutation	NA	R232K	0.25
SKCM	chr7	150477727	Missense_Mutation	NA	E649K	0.43
SKCM	chr7	150477131	Missense_Mutation	NA	G450E	0.32	MMR_HSR1
SKCM	chr7	150477184	Missense_Mutation	novel	L468I	0.21	MMR_HSR1
SKCM	chr7	150474438	Missense_Mutation	NA	G370E	0.27
SKCM	chr7	150477490	Silent	rs755463565	L570L	0.28
SKCM	chr7	150466747	Missense_Mutation	NA	G17R	0.51
SKCM	chr7	150466850	Missense_Mutation	rs758956378	R51K	0.11
SKCM	chr7	150477661	Missense_Mutation	NA	E627K	0.16
SKCM	chr7	150477453	Silent	rs557029400	T557T	0.07
SKCM	chr7	150467102	Missense_Mutation	rs761170315	R135Q	0.3
SKCM	chr7	150467283	Silent	NA	T195T	0.19
SKCM	chr7	150477445	Missense_Mutation	NA	D555N	0.08
SKCM	chr7	150467110	Missense_Mutation	rs754436007	D138N	0.11
SKCM	chr7	150477830	3'UTR	novel		0.57
SKCM	chr7	150467253	Silent	NA	L185L	0.27
SKCM	chr7	150466836	Silent	NA	I46I	0.2
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.42
SKCM	chr7	150474296	Missense_Mutation	NA	G323S	0.11
SKCM	chr7	150477612	Silent	novel	Q610Q	0.51
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.1
SKCM	chr7	150467016	Silent	NA	F106F	0.37
SKCM	chr7	150466822	Missense_Mutation	NA	D42N	0.43
SKCM	chr7	150477806	3'UTR	novel		0.62
SKCM	chr7	150477828	3'UTR	rs775362131		0.31
SKCM	chr7	150474210	Missense_Mutation	NA	R294K	0.23
SKCM	chr7	150477606	Silent	NA	Q608Q	0.12
SKCM	chr7	150477131	Missense_Mutation	NA	G450E	0.4	MMR_HSR1
SKCM	chr7	150477132	Silent	NA	G450G	0.39
SKCM	chr7	150477214	Nonsense_Mutation	NA	Q478*	0.22	MMR_HSR1
SKCM	chr7	150477462	Silent	NA	A560A	0.08
SKCM	chr7	150474036	Missense_Mutation	NA	S236F	0.24
SKCM	chr7	150477727	Missense_Mutation	NA	E649K	0.53
SKCM	chr7	150474226	Silent	NA	S299S	0.13
SKCM	chr7	150474105	Missense_Mutation	NA	G259E	0.41
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.2
SKCM	chr7	150477525	Silent	NA	N581N	0.13
SKCM	chr7	150477787	3'UTR	novel		0.3
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.31
SKCM	chr7	150474578	Missense_Mutation	NA	E417K	0.64
SKCM	chr7	150467139	Silent	NA	F147F	0.83
SKCM	chr7	150477742	Missense_Mutation	rs750008473	E654K	0.42
SKCM	chr7	150466870	Missense_Mutation	NA	E58K	0.56
SKCM	chr7	150477595	Missense_Mutation	NA	E605K	0.43
SKCM	chr7	150477453	Silent	rs557029400	T557T	0.74
SKCM	chr7	150477477	Silent	novel	T565T	0.5
SKCM	chr7	150474210	Missense_Mutation	NA	R294K	0.35
SKCM	chr7	150477727	Missense_Mutation	NA	E649K	0.47
SKCM	chr7	150467235	Silent	NA	I179I	0.3
STAD	chr7	150467143	Frame_Shift_Ins	rs746795576	*N151Kfs12**	0.43
STAD	chr7	150477347	Frame_Shift_Del	novel	*D525Tfs46**	0.37	MMR_HSR1
STAD	chr7	150467258	Missense_Mutation	rs200592029	R187H	0.24
STAD	chr7	150467281	Missense_Mutation	NA	T195A	0.17
STAD	chr7	150477548	Missense_Mutation	NA	R589H	0.32
STAD	chr7	150477419	Missense_Mutation	NA	A546V	0.13
STAD	chr7	150477512	Missense_Mutation	NA	D577V	0.34
STAD	chr7	150467143	Frame_Shift_Ins	rs746795576	*N151Kfs12**	0.13
STAD	chr7	150477545	Missense_Mutation	rs200505163	R588Q	0.3
STAD	chr7	150477548	Missense_Mutation	NA	R589H	0.37
STAD	chr7	150474096	Missense_Mutation	NA	R256H	0.25
STAD	chr7	150477291	Silent	rs369326425	V503V	0.27
STAD	chr7	150467191	Missense_Mutation	NA	Y165H	0.2
STAD	chr7	150474241	Silent	rs768970689	P304P	0.06
STAD	chr7	150466956	Silent	novel	C86C	0.11
THCA	chr7	150474634	Frame_Shift_Ins	novel	*K436Rfs3**	0.07
THCA	chr7	150467095	Nonsense_Mutation	novel	F133*	0.05
THYM	chr7	150477548	Missense_Mutation	NA	R589H	0.05
THYM	chr7	150477419	Missense_Mutation	novel	A546E	0.18
UCEC	chr7	150467134	Missense_Mutation	NA	D146Y	0.3
UCEC	chr7	150474565	Silent	rs149276246	A412A	0.35
UCEC	chr7	150477751	Missense_Mutation	NA	L657I	0.35
UCEC	chr7	150466758	Silent	novel	R20R	0.15
UCEC	chr7	150467079	Silent	novel	R127R	0.39
UCEC	chr7	150474243	Missense_Mutation	novel	D305G	0.24
UCEC	chr7	150474522	Missense_Mutation	novel	A398V	0.28
UCEC	chr7	150470847	Missense_Mutation	NA	A219T	0.32
UCEC	chr7	150477460	Missense_Mutation	rs759430794	A560T	0.4
UCEC	chr7	150477545	Missense_Mutation	rs200505163	R588Q	0.31
UCEC	chr7	150466827	Missense_Mutation	NA	Q43H	0.13
UCEC	chr7	150474241	Silent	rs768970689	P304P	0.21
UCEC	chr7	150474569	Missense_Mutation	rs771833252	E414K	0.22
UCEC	chr7	150474095	Missense_Mutation	rs576578780	R256C	0.3
UCEC	chr7	150467283	Silent	NA	T195T	0.51
UCEC	chr7	150474558	Missense_Mutation	NA	R410M	0.43
UCEC	chr7	150477453	Silent	rs557029400	T557T	0.46
UCEC	chr7	150467002	Missense_Mutation	NA	A102T	0.3
UCEC	chr7	150466870	Nonsense_Mutation	novel	E58*	0.29
UCEC	chr7	150470874	Missense_Mutation	novel	G228S	0.3
UCEC	chr7	150466940	Missense_Mutation	rs772996358	R81H	0.26
UCEC	chr7	150474241	Silent	rs768970689	P304P	0.38
UCEC	chr7	150477496	Missense_Mutation	novel	A572T	0.54
UCEC	chr7	150474225	Missense_Mutation	NA	S299L	0.33
UCEC	chr7	150474513	Missense_Mutation	novel	R395I	0.53
UCEC	chr7	150477420	Silent	NA	A546A	0.34
UCEC	chr7	150467143	Frame_Shift_Ins	rs746795576	*N151Kfs12**	0.4
UCEC	chr7	150466761	Silent	rs770460277	S21S	0.24
UCEC	chr7	150477446	Missense_Mutation	NA	D555G	0.31
UCEC	chr7	150477420	Silent	NA	A546A	0.41
UCEC	chr7	150467156	Missense_Mutation	novel	P153H	0.39
UCEC	chr7	150477187	Missense_Mutation	rs529904898	R469W	0.24	MMR_HSR1
UCEC	chr7	150474047	Missense_Mutation	rs759454503	E240K	0.21
UCEC	chr7	150477292	Missense_Mutation	rs180888093	E504K	0.11	MMR_HSR1
UCEC	chr7	150467095	Missense_Mutation	novel	F133L	0.16
UCEC	chr7	150474259	Missense_Mutation	novel	K310N	0.26
UCEC	chr7	150474217	Missense_Mutation	novel	K296N	0.52
UCEC	chr7	150474151	Missense_Mutation	novel	Q274H	0.34
UCEC	chr7	150477459	Silent	NA	Y559Y	0.07
UCEC	chr7	150467085	Silent	novel	I129I	0.27
UCEC	chr7	150474077	Missense_Mutation	rs79397821	V250I	0.42
UCEC	chr7	150477879	3'UTR	novel		0.33
UCEC	chr7	150474292	Silent	novel	C321C	0.22
UCEC	chr7	150477952	3'UTR	novel		0.46
UCEC	chr7	150466998	Silent	novel	V100V	0.51
UCEC	chr7	150467178	Missense_Mutation	novel	D160E	0.43
UCEC	chr7	150467253	Silent	novel	L185L	0.33
UCEC	chr7	150477835	3'UTR	novel		0.33
UCS	chr7	150467134	Missense_Mutation	NA	D146Y	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0778	0.12261
CESC	DEL	0.1797	0.0016147
DLBC	DEL	0.0833	0.03486
HNSC	DEL	0.2031	1.1399e-22
KIRC	AMP	0.2898	0.075418
LAML	DEL	0.1309	3.4101e-05
LGG	AMP	0.3119	1.5525e-07
LIHC	DEL	0.0811	0.24831
OV	AMP	0.4784	1.5763e-13
PAAD	DEL	0.0652	0.049388
TGCT	DEL	0.0733	0.11738
THCA	DEL	0	0.27619
UCEC	DEL	0.0983	0.0001859
UCS	DEL	0.3393	0.10142

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0083	Kaplan-Meier Survival Analysis
KIRC	0.00011	Kaplan-Meier Survival Analysis
SARC	0.00071	Kaplan-Meier Survival Analysis
ACC	0.017	Kaplan-Meier Survival Analysis
HNSC	0.026	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
LUSC	0.025	Kaplan-Meier Survival Analysis
PAAD	0.0067	Kaplan-Meier Survival Analysis
CESC	0.0037	Kaplan-Meier Survival Analysis
UCEC	0.0043	Kaplan-Meier Survival Analysis
LIHC	0.0042	Kaplan-Meier Survival Analysis
LUAD	0.00013	Kaplan-Meier Survival Analysis
UVM	0.00098	Kaplan-Meier Survival Analysis