EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171311 (Gene tree)
Gene ID: 51013
Gene Symbol: EXOSC1
Alias: hCsl4p|Csl4p|CSL4|Ski4p|SKI4|CGI-108|p13
Full Name: exosome component 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 10,109 bases
Position: chr10:97,435,909-97,446,017
Accession: 17286
RBP type: canonical RBP
Summary: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000359939	EXOSC1	PF10447.9	2.4e-14	1	1
ENSP00000359922	EXOSC1	PF10447.9	8e-13	1	1
ENSP00000473303	EXOSC1	PF10447.9	2.7e-07	1	1
ENSP00000473660	ECR1_N	PF14382.6	1.6e-08	1	1
ENSP00000359921	ECR1_N	PF14382.6	1.8e-08	1	1
ENSP00000359922	ECR1_N	PF14382.6	2e-08	1	1
ENSP00000359939	ECR1_N	PF14382.6	2.5e-08	1	1
ENSP00000359923	ECR1_N	PF14382.6	2.6e-08	1	1
ENSP00000473303	ECR1_N	PF14382.6	3.9e-06	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23324612	The archaeal DnaG protein needs Csl4 for binding to the exosome and enhances its interaction with adenine-rich RNAs.	RNA Biol	2013 Mar	Hou L	doi: 10.4161/rna.23450
29159940	Nop5 interacts with the archaeal RNA exosome.	FEBS Lett	2017 Dec	Gauernack AS	doi: 10.1002/1873-3468.12915
12947419	An exosome-like complex in Sulfolobus solfataricus.	EMBO Rep	2003 Sep	Evguenieva-Hackenberg E	-
11027292	Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA.	Mol Cell Biol	2000 Nov	van Hoof A	-
22503705	Heterogeneous complexes of the RNA exosome in Sulfolobus solfataricus.	Biochimie	2012 Jul	Witharana C	doi: 10.1016/j.biochi.2012.03.026
22068837	Yeast RNA viruses as indicators of exosome activity: human exosome hCsl4p participates in RNA degradation in Saccharomyces cerevisiae'.	Yeast	2011 Dec	Ramirez-Garrastacho M	doi: 10.1002/yea.1909
21713675	The archaeal exosome.	Adv Exp Med Biol	2011	Evguenieva-Hackenberg E	doi: 10.1007/978-1-4419-7841-7_3.
20488184	The evolutionarily conserved subunits Rrp4 and Csl4 confer different substrate specificities to the archaeal exosome.	FEBS Lett	2010 Jul 2	Roppelt V	doi: 10.1016/j.febslet.2010.05.014
25326320	Archaeal DnaG contains a conserved N-terminal RNA-binding domain and enables tailing of rRNA by the exosome.	Nucleic Acids Res	2014 Nov 10	Hou L	doi: 10.1093/nar/gku969
24789718	Structure and function of the archaeal exosome.	Wiley Interdiscip Rev RNA	2014 Sep-Oct	Evguenieva-Hackenberg E	doi: 10.1002/wrna.1234

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000474309	EXOSC1-207	260	-	-	- (aa)	-	-
ENST00000471049	EXOSC1-205	642	-	-	- (aa)	-	-
ENST00000476234	EXOSC1-208	739	-	-	- (aa)	-	-
ENST00000489158	EXOSC1-211	2113	-	-	- (aa)	-	-
ENST00000472345	EXOSC1-206	451	-	-	- (aa)	-	-
ENST00000477692	EXOSC1-209	480	-	ENSP00000473303	143 (aa)	-	R4GMQ7
ENST00000370885	EXOSC1-202	718	XM_017016304	ENSP00000359922	170 (aa)	XP_016871793	B1AMU3
ENST00000370884	EXOSC1-201	536	-	ENSP00000359921	165 (aa)	-	B1AMU7
ENST00000370886	EXOSC1-203	741	-	ENSP00000359923	178 (aa)	-	B1AMU4
ENST00000485122	EXOSC1-210	564	-	ENSP00000473660	139 (aa)	-	R4GNH9
ENST00000370902	EXOSC1-204	923	XM_011539847	ENSP00000359939	195 (aa)	XP_011538149	Q9Y3B2

Gene Model

Click here to download ENSG00000171311's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171311's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171311	EXOSC1	98	80.105	ENSAPOG00000007822	exosc1	98	80.105	Acanthochromis_polyacanthus
ENSG00000171311	EXOSC1	100	97.436	ENSAMEG00000000129	EXOSC1	100	97.436	Ailuropoda_melanoleuca
ENSG00000171311	EXOSC1	96	79.787	ENSACIG00000018956	exosc1	92	79.787	Amphilophus_citrinellus
ENSG00000171311	EXOSC1	98	80.105	ENSAOCG00000010699	exosc1	98	80.105	Amphiprion_ocellaris
ENSG00000171311	EXOSC1	91	78.395	ENSAPEG00000012690	exosc1	96	78.395	Amphiprion_percula
ENSG00000171311	EXOSC1	98	79.581	ENSATEG00000018683	exosc1	98	79.581	Anabas_testudineus
ENSG00000171311	EXOSC1	99	84.456	ENSACAG00000002101	EXOSC1	99	84.456	Anolis_carolinensis
ENSG00000171311	EXOSC1	100	98.824	ENSANAG00000034669	EXOSC1	100	98.824	Aotus_nancymaae
ENSG00000171311	EXOSC1	98	80.105	ENSACLG00000021243	exosc1	98	80.105	Astatotilapia_calliptera
ENSG00000171311	EXOSC1	98	81.675	ENSAMXG00000011116	exosc1	98	81.675	Astyanax_mexicanus
ENSG00000171311	EXOSC1	100	96.923	ENSBTAG00000012699	EXOSC1	100	96.923	Bos_taurus
ENSG00000171311	EXOSC1	92	32.979	WBGene00012966	exos-1	90	32.979	Caenorhabditis_elegans
ENSG00000171311	EXOSC1	100	98.235	ENSCJAG00000016586	EXOSC1	100	98.701	Callithrix_jacchus
ENSG00000171311	EXOSC1	100	96.923	ENSCAFG00000009068	EXOSC1	94	96.923	Canis_familiaris
ENSG00000171311	EXOSC1	100	96.923	ENSCAFG00020006002	EXOSC1	94	96.923	Canis_lupus_dingo
ENSG00000171311	EXOSC1	100	96.923	ENSCHIG00000015253	EXOSC1	100	96.923	Capra_hircus
ENSG00000171311	EXOSC1	100	97.059	ENSTSYG00000000760	EXOSC1	100	97.059	Carlito_syrichta
ENSG00000171311	EXOSC1	100	96.923	ENSCPOG00000001173	EXOSC1	100	96.923	Cavia_porcellus
ENSG00000171311	EXOSC1	100	62.353	ENSCCAG00000023986	EXOSC1	100	62.353	Cebus_capucinus
ENSG00000171311	EXOSC1	100	100.000	ENSCATG00000034114	EXOSC1	100	100.000	Cercocebus_atys
ENSG00000171311	EXOSC1	100	97.436	ENSCLAG00000002463	EXOSC1	100	97.436	Chinchilla_lanigera
ENSG00000171311	EXOSC1	100	99.487	ENSCSAG00000005870	EXOSC1	100	99.487	Chlorocebus_sabaeus
ENSG00000171311	EXOSC1	96	82.888	ENSCHOG00000006477	EXOSC1	100	82.888	Choloepus_hoffmanni
ENSG00000171311	EXOSC1	81	79.646	ENSCPBG00000011949	EXOSC1	93	79.646	Chrysemys_picta_bellii
ENSG00000171311	EXOSC1	95	56.150	ENSCING00000022734	-	89	56.150	Ciona_intestinalis
ENSG00000171311	EXOSC1	95	57.754	ENSCSAVG00000010865	-	95	57.754	Ciona_savignyi
ENSG00000171311	EXOSC1	100	100.000	ENSCANG00000034159	EXOSC1	100	100.000	Colobus_angolensis_palliatus
ENSG00000171311	EXOSC1	100	95.897	ENSCGRG00001000335	Exosc1	100	96.753	Cricetulus_griseus_chok1gshd
ENSG00000171311	EXOSC1	100	95.897	ENSCGRG00000011602	Exosc1	100	96.753	Cricetulus_griseus_crigri
ENSG00000171311	EXOSC1	98	77.108	ENSCSEG00000007895	exosc1	95	77.108	Cynoglossus_semilaevis
ENSG00000171311	EXOSC1	98	76.440	ENSCVAG00000016748	exosc1	98	76.440	Cyprinodon_variegatus
ENSG00000171311	EXOSC1	98	80.628	ENSDARG00000059841	exosc1	98	80.628	Danio_rerio
ENSG00000171311	EXOSC1	86	94.167	ENSDNOG00000007983	EXOSC1	100	97.297	Dasypus_novemcinctus
ENSG00000171311	EXOSC1	100	96.410	ENSDORG00000016528	Exosc1	100	96.410	Dipodomys_ordii
ENSG00000171311	EXOSC1	94	48.148	FBgn0032346	Csl4	92	48.148	Drosophila_melanogaster
ENSG00000171311	EXOSC1	100	94.872	ENSETEG00000002469	-	100	94.872	Echinops_telfairi
ENSG00000171311	EXOSC1	99	62.245	ENSEBUG00000008164	exosc1	98	62.245	Eptatretus_burgeri
ENSG00000171311	EXOSC1	100	88.298	ENSEASG00005008684	EXOSC1	100	88.298	Equus_asinus_asinus
ENSG00000171311	EXOSC1	100	82.734	ENSECAG00000010621	EXOSC1	84	82.734	Equus_caballus
ENSG00000171311	EXOSC1	100	96.923	ENSEEUG00000005647	EXOSC1	100	96.923	Erinaceus_europaeus
ENSG00000171311	EXOSC1	94	80.978	ENSELUG00000017369	exosc1	97	71.856	Esox_lucius
ENSG00000171311	EXOSC1	100	98.235	ENSFCAG00000040563	EXOSC1	100	98.235	Felis_catus
ENSG00000171311	EXOSC1	100	83.077	ENSFALG00000008450	EXOSC1	100	83.077	Ficedula_albicollis
ENSG00000171311	EXOSC1	100	97.436	ENSFDAG00000000846	EXOSC1	100	97.436	Fukomys_damarensis
ENSG00000171311	EXOSC1	98	76.440	ENSFHEG00000009154	exosc1	98	76.440	Fundulus_heteroclitus
ENSG00000171311	EXOSC1	98	80.105	ENSGMOG00000008993	exosc1	98	80.105	Gadus_morhua
ENSG00000171311	EXOSC1	100	82.353	ENSGALG00000039917	EXOSC1	100	86.301	Gallus_gallus
ENSG00000171311	EXOSC1	98	76.963	ENSGAFG00000010265	exosc1	94	76.963	Gambusia_affinis
ENSG00000171311	EXOSC1	98	80.105	ENSGACG00000018936	exosc1	98	80.105	Gasterosteus_aculeatus
ENSG00000171311	EXOSC1	100	85.128	ENSGAGG00000019192	EXOSC1	100	85.128	Gopherus_agassizii
ENSG00000171311	EXOSC1	100	98.824	ENSGGOG00000003099	EXOSC1	100	98.824	Gorilla_gorilla
ENSG00000171311	EXOSC1	98	80.105	ENSHBUG00000017857	exosc1	98	80.105	Haplochromis_burtoni
ENSG00000171311	EXOSC1	100	96.923	ENSHGLG00000016927	EXOSC1	100	97.403	Heterocephalus_glaber_female
ENSG00000171311	EXOSC1	100	96.923	ENSHGLG00100012208	EXOSC1	100	97.403	Heterocephalus_glaber_male
ENSG00000171311	EXOSC1	98	79.058	ENSHCOG00000019882	exosc1	98	79.058	Hippocampus_comes
ENSG00000171311	EXOSC1	98	80.105	ENSIPUG00000007685	exosc1	98	80.105	Ictalurus_punctatus
ENSG00000171311	EXOSC1	100	97.436	ENSSTOG00000006615	EXOSC1	100	97.436	Ictidomys_tridecemlineatus
ENSG00000171311	EXOSC1	86	84.298	ENSSTOG00000029860	-	93	84.298	Ictidomys_tridecemlineatus
ENSG00000171311	EXOSC1	100	96.410	ENSJJAG00000013311	Exosc1	100	96.410	Jaculus_jaculus
ENSG00000171311	EXOSC1	98	78.125	ENSKMAG00000001202	exosc1	81	78.125	Kryptolebias_marmoratus
ENSG00000171311	EXOSC1	98	79.581	ENSLBEG00000011448	exosc1	98	79.581	Labrus_bergylta
ENSG00000171311	EXOSC1	91	75.641	ENSLOCG00000003776	exosc1	98	75.641	Lepisosteus_oculatus
ENSG00000171311	EXOSC1	100	96.923	ENSLAFG00000015983	EXOSC1	100	96.923	Loxodonta_africana
ENSG00000171311	EXOSC1	100	100.000	ENSMFAG00000001493	EXOSC1	100	100.000	Macaca_fascicularis
ENSG00000171311	EXOSC1	100	100.000	ENSMMUG00000020028	EXOSC1	100	100.000	Macaca_mulatta
ENSG00000171311	EXOSC1	100	100.000	ENSMNEG00000029816	EXOSC1	100	100.000	Macaca_nemestrina
ENSG00000171311	EXOSC1	100	94.359	ENSMLEG00000027643	EXOSC1	100	100.000	Mandrillus_leucophaeus
ENSG00000171311	EXOSC1	98	80.628	ENSMAMG00000012200	exosc1	98	80.628	Mastacembelus_armatus
ENSG00000171311	EXOSC1	98	80.105	ENSMZEG00005007042	exosc1	98	80.105	Maylandia_zebra
ENSG00000171311	EXOSC1	100	96.471	ENSMAUG00000020462	-	100	96.471	Mesocricetus_auratus
ENSG00000171311	EXOSC1	100	97.059	ENSMICG00000007664	EXOSC1	100	97.059	Microcebus_murinus
ENSG00000171311	EXOSC1	100	95.897	ENSMOCG00000006004	-	100	96.753	Microtus_ochrogaster
ENSG00000171311	EXOSC1	97	89.474	ENSMOCG00000017124	-	97	89.474	Microtus_ochrogaster
ENSG00000171311	EXOSC1	93	77.124	ENSMMOG00000021403	exosc1	99	77.124	Mola_mola
ENSG00000171311	EXOSC1	100	91.837	ENSMODG00000004213	EXOSC1	100	91.837	Monodelphis_domestica
ENSG00000171311	EXOSC1	94	80.978	ENSMALG00000007061	exosc1	92	80.978	Monopterus_albus
ENSG00000171311	EXOSC1	100	95.385	MGP_CAROLIEiJ_G0022959	Exosc1	100	96.104	Mus_caroli
ENSG00000171311	EXOSC1	100	95.897	ENSMUSG00000034321	Exosc1	100	96.753	Mus_musculus
ENSG00000171311	EXOSC1	100	95.897	MGP_PahariEiJ_G0014449	Exosc1	100	96.753	Mus_pahari
ENSG00000171311	EXOSC1	100	95.385	MGP_SPRETEiJ_G0023880	Exosc1	100	96.104	Mus_spretus
ENSG00000171311	EXOSC1	100	97.436	ENSMPUG00000017044	EXOSC1	100	97.436	Mustela_putorius_furo
ENSG00000171311	EXOSC1	100	96.923	ENSMLUG00000009228	EXOSC1	100	96.923	Myotis_lucifugus
ENSG00000171311	EXOSC1	100	94.872	ENSNGAG00000022033	Exosc1	100	94.872	Nannospalax_galili
ENSG00000171311	EXOSC1	91	78.000	ENSNBRG00000024007	exosc1	97	78.000	Neolamprologus_brichardi
ENSG00000171311	EXOSC1	100	99.487	ENSNLEG00000013872	EXOSC1	100	100.000	Nomascus_leucogenys
ENSG00000171311	EXOSC1	83	90.435	ENSMEUG00000002246	EXOSC1	100	90.435	Notamacropus_eugenii
ENSG00000171311	EXOSC1	100	95.385	ENSOPRG00000005065	EXOSC1	100	95.385	Ochotona_princeps
ENSG00000171311	EXOSC1	100	96.923	ENSODEG00000016709	EXOSC1	100	96.923	Octodon_degus
ENSG00000171311	EXOSC1	98	80.105	ENSONIG00000017683	exosc1	98	80.105	Oreochromis_niloticus
ENSG00000171311	EXOSC1	68	93.043	ENSOANG00000006563	EXOSC1	100	90.476	Ornithorhynchus_anatinus
ENSG00000171311	EXOSC1	100	95.918	ENSOCUG00000011898	-	100	95.918	Oryctolagus_cuniculus
ENSG00000171311	EXOSC1	100	90.769	ENSOCUG00000026461	-	100	90.769	Oryctolagus_cuniculus
ENSG00000171311	EXOSC1	98	78.646	ENSORLG00000011595	exosc1	98	78.646	Oryzias_latipes
ENSG00000171311	EXOSC1	98	78.646	ENSORLG00020005831	exosc1	98	78.646	Oryzias_latipes_hni
ENSG00000171311	EXOSC1	98	78.646	ENSORLG00015004317	exosc1	98	78.646	Oryzias_latipes_hsok
ENSG00000171311	EXOSC1	98	63.874	ENSOMEG00000013907	exosc1	98	65.318	Oryzias_melastigma
ENSG00000171311	EXOSC1	100	96.410	ENSOGAG00000016259	EXOSC1	100	96.410	Otolemur_garnettii
ENSG00000171311	EXOSC1	100	96.410	ENSOARG00000010136	EXOSC1	100	96.410	Ovis_aries
ENSG00000171311	EXOSC1	100	93.909	ENSPPAG00000039842	EXOSC1	100	100.000	Pan_paniscus
ENSG00000171311	EXOSC1	100	98.235	ENSPPRG00000023366	EXOSC1	100	98.235	Panthera_pardus
ENSG00000171311	EXOSC1	100	98.235	ENSPTIG00000017701	EXOSC1	100	98.235	Panthera_tigris_altaica
ENSG00000171311	EXOSC1	100	100.000	ENSPTRG00000002808	EXOSC1	100	100.000	Pan_troglodytes
ENSG00000171311	EXOSC1	100	100.000	ENSPANG00000021324	EXOSC1	100	100.000	Papio_anubis
ENSG00000171311	EXOSC1	98	80.628	ENSPKIG00000016037	exosc1	98	80.628	Paramormyrops_kingsleyae
ENSG00000171311	EXOSC1	75	82.192	ENSPSIG00000013571	EXOSC1	98	80.992	Pelodiscus_sinensis
ENSG00000171311	EXOSC1	98	77.108	ENSPMGG00000014002	exosc1	98	77.108	Periophthalmus_magnuspinnatus
ENSG00000171311	EXOSC1	100	95.897	ENSPEMG00000010710	-	100	96.753	Peromyscus_maniculatus_bairdii
ENSG00000171311	EXOSC1	95	71.123	ENSPMAG00000000195	exosc1	95	71.123	Petromyzon_marinus
ENSG00000171311	EXOSC1	100	92.821	ENSPCIG00000002210	EXOSC1	99	92.821	Phascolarctos_cinereus
ENSG00000171311	EXOSC1	98	76.440	ENSPFOG00000006755	exosc1	94	76.440	Poecilia_formosa
ENSG00000171311	EXOSC1	98	76.440	ENSPLAG00000005880	exosc1	98	76.440	Poecilia_latipinna
ENSG00000171311	EXOSC1	98	76.440	ENSPMEG00000015598	exosc1	94	76.440	Poecilia_mexicana
ENSG00000171311	EXOSC1	98	74.699	ENSPREG00000000405	exosc1	93	74.699	Poecilia_reticulata
ENSG00000171311	EXOSC1	100	99.487	ENSPPYG00000002531	EXOSC1	100	99.487	Pongo_abelii
ENSG00000171311	EXOSC1	100	96.410	ENSPCAG00000009135	EXOSC1	100	96.410	Procavia_capensis
ENSG00000171311	EXOSC1	100	90.769	ENSPCOG00000027539	EXOSC1	100	90.769	Propithecus_coquereli
ENSG00000171311	EXOSC1	100	97.436	ENSPVAG00000003372	EXOSC1	100	97.436	Pteropus_vampyrus
ENSG00000171311	EXOSC1	98	80.105	ENSPNYG00000021745	exosc1	98	80.105	Pundamilia_nyererei
ENSG00000171311	EXOSC1	98	80.628	ENSPNAG00000001944	exosc1	98	80.628	Pygocentrus_nattereri
ENSG00000171311	EXOSC1	100	95.897	ENSRNOG00000048708	Exosc1	100	96.753	Rattus_norvegicus
ENSG00000171311	EXOSC1	100	100.000	ENSRBIG00000035618	EXOSC1	100	100.000	Rhinopithecus_bieti
ENSG00000171311	EXOSC1	100	100.000	ENSRROG00000032589	EXOSC1	100	100.000	Rhinopithecus_roxellana
ENSG00000171311	EXOSC1	56	47.959	YNL232W	CSL4	54	36.250	Saccharomyces_cerevisiae
ENSG00000171311	EXOSC1	100	98.824	ENSSBOG00000000359	EXOSC1	100	98.824	Saimiri_boliviensis_boliviensis
ENSG00000171311	EXOSC1	75	95.238	ENSSHAG00000018219	EXOSC1	100	95.238	Sarcophilus_harrisii
ENSG00000171311	EXOSC1	98	81.675	ENSSFOG00015009069	exosc1	98	81.675	Scleropages_formosus
ENSG00000171311	EXOSC1	98	77.844	ENSSFOG00015016289	-	98	78.421	Scleropages_formosus
ENSG00000171311	EXOSC1	98	80.628	ENSSMAG00000003721	exosc1	98	80.628	Scophthalmus_maximus
ENSG00000171311	EXOSC1	98	80.628	ENSSDUG00000002993	exosc1	98	80.628	Seriola_dumerili
ENSG00000171311	EXOSC1	98	80.628	ENSSLDG00000025181	exosc1	98	80.628	Seriola_lalandi_dorsalis
ENSG00000171311	EXOSC1	100	83.590	ENSSARG00000000162	EXOSC1	100	83.590	Sorex_araneus
ENSG00000171311	EXOSC1	99	84.536	ENSSPUG00000012263	EXOSC1	99	84.536	Sphenodon_punctatus
ENSG00000171311	EXOSC1	98	78.736	ENSSPAG00000016792	exosc1	82	78.736	Stegastes_partitus
ENSG00000171311	EXOSC1	100	96.410	ENSSSCG00000010518	EXOSC1	91	96.410	Sus_scrofa
ENSG00000171311	EXOSC1	98	81.250	ENSTGUG00000009692	EXOSC1	99	81.250	Taeniopygia_guttata
ENSG00000171311	EXOSC1	97	74.074	ENSTRUG00000007706	exosc1	98	74.074	Takifugu_rubripes
ENSG00000171311	EXOSC1	97	73.958	ENSTNIG00000014079	exosc1	97	73.958	Tetraodon_nigroviridis
ENSG00000171311	EXOSC1	100	88.718	ENSTBEG00000006011	EXOSC1	100	88.718	Tupaia_belangeri
ENSG00000171311	EXOSC1	94	97.283	ENSTTRG00000009887	EXOSC1	100	97.283	Tursiops_truncatus
ENSG00000171311	EXOSC1	100	80.000	ENSUAMG00000010266	EXOSC1	100	83.240	Ursus_americanus
ENSG00000171311	EXOSC1	100	81.026	ENSUMAG00000022002	EXOSC1	100	83.240	Ursus_maritimus
ENSG00000171311	EXOSC1	100	96.923	ENSVVUG00000023192	EXOSC1	63	96.923	Vulpes_vulpes
ENSG00000171311	EXOSC1	98	78.646	ENSXETG00000003434	exosc1	99	78.646	Xenopus_tropicalis
ENSG00000171311	EXOSC1	71	84.167	ENSXCOG00000014499	exosc1	92	84.167	Xiphophorus_couchianus
ENSG00000171311	EXOSC1	98	75.301	ENSXMAG00000023382	exosc1	93	75.301	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000176	nuclear exosome (RNase complex)	21873635.	IBA	Component
GO:0000178	exosome (RNase complex)	20531389.	IDA	Component
GO:0000178	exosome (RNase complex)	11812149.	NAS	Component
GO:0003723	RNA binding	11812149.	NAS	Function
GO:0004532	exoribonuclease activity	17174896.	IDA	Function
GO:0005515	protein binding	11812149.12419256.12788944.15231747.19060904.20531386.21791617.25043052.25416956.26496610.27107012.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	11812149.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0043488	regulation of mRNA stability	-	TAS	Process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process