EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171316 (Gene tree)
Gene ID: 55636
Gene Symbol: CHD7
Alias: KIAA1416|FLJ20357|FLJ20361|CRG
Full Name: chromodomain helicase DNA binding protein 7
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 189,267 bases
Position: chr8:60,678,762-60,868,028
Accession: 20626
RBP type: canonical RBP
Summary: This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000392028	ResIII	PF04851.15	6.9e-06	1	1
ENSP00000436027	ResIII	PF04851.15	1.6e-05	1	1
ENSP00000392028	BRK	PF07533.16	9.5e-37	1	2
ENSP00000392028	BRK	PF07533.16	9.5e-37	2	2
ENSP00000437061	BRK	PF07533.16	2.7e-18	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000618450	CHD7-212	4222	-	-	- (aa)	-	-
ENST00000532149	CHD7-211	616	-	-	- (aa)	-	-
ENST00000529472	CHD7-209	788	-	-	- (aa)	-	-
ENST00000531695	CHD7-210	507	-	-	- (aa)	-	-
ENST00000526846	CHD7-204	500	-	ENSP00000436492	32 (aa)	-	E9PP20
ENST00000423902	CHD7-201	11568	XM_011517553	ENSP00000392028	2997 (aa)	XP_011515855	Q9P2D1
ENST00000527825	CHD7-205	434	-	ENSP00000432627	19 (aa)	-	H0YD01
ENST00000527900	CHD7-206	398	-	ENSP00000433336	39 (aa)	-	H0YDC1
ENST00000524602	CHD7-202	3456	-	ENSP00000437061	948 (aa)	-	Q9P2D1
ENST00000525508	CHD7-203	4777	-	ENSP00000436027	1138 (aa)	-	Q9P2D1
ENST00000527921	CHD7-207	527	-	-	- (aa)	-	-
ENST00000528280	CHD7-208	566	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000171316's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000171316	Body Height	6.4991661715621E-8	17903300
ENSG00000171316	Body Weight	8.08588876748955E-9	17903300
ENSG00000171316	Triglycerides	7.86847358119178E-7	17903299
ENSG00000171316	Triglycerides	8.17469716121315E-8	17903299
ENSG00000171316	Triglycerides	2.83013967936508E-10	17903299
ENSG00000171316	Triglycerides	7.65111127196717E-14	17903299
ENSG00000171316	Triglycerides	7.74622274729761E-6	17903299
ENSG00000171316	Triglycerides	1.31407092420857E-10	17903299
ENSG00000171316	Urinalysis	8.11426262097292E-5	17903293
ENSG00000171316	Echocardiography	1.32670740037938E-6	17903301
ENSG00000171316	Echocardiography	9.52858978213228E-6	17903301
ENSG00000171316	Hip	3.85677855240951E-7	17903296
ENSG00000171316	Pulse Wave Analysis	9.147e-005	-
ENSG00000171316	Platelet Function Tests	3.9710776E-006	-
ENSG00000171316	Platelet Function Tests	1.1756800E-005	-
ENSG00000171316	Platelet Function Tests	9.0791570E-006	-
ENSG00000171316	Platelet Function Tests	1.0142100E-005	-
ENSG00000171316	Platelet Function Tests	1.0222700E-005	-
ENSG00000171316	Platelet Function Tests	1.2388900E-005	-
ENSG00000171316	3-hydroxy-1-methylpropylmercapturic acid	4E-6	26053186
ENSG00000171316	Smoking	4E-6	26053186

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000171316	rs187025166	8	60680319	?	3-hydroxy-1-methylpropylmercapturic acid levels in smokers	26053186	[NR] unit decrease	0.8255	EFO_0004318\|EFO_0007015
ENSG00000171316	rs10957156	8	60716842	A	Menopause (age at onset)	26414677	[0.1-0.18] years decrease	0.14	EFO_0004704
ENSG00000171316	rs4289855	8	60799811	T	Major depressive disorder	29728651	[NR]	1.036	EFO_0003761
ENSG00000171316	rs13280978	8	60791496	?	White blood cell count	29403010	[0.027-0.047] unit decrease novel	0.03682	EFO_0004308
ENSG00000171316	rs4237036	8	60788498	?	Neutrophil count	29403010	[0.038-0.065] unit decrease novel	0.05135	EFO_0004833
ENSG00000171316	rs6994642	8	60811218	?	Eosinophil counts	29403010	[0.027-0.056] unit decrease novel	0.04171	EFO_0004842
ENSG00000171316	rs7846314	8	60738272	T	Granulocyte percentage of myeloid white cells	27863252	[0.049-0.067] unit increase	0.05759455	EFO_0007997
ENSG00000171316	rs35440906	8	60733793	CA	Lymphocyte percentage of white cells	27863252	[0.037-0.055] unit decrease	0.04561981	EFO_0007993
ENSG00000171316	rs7846314	8	60738272	T	Myeloid white cell count	27863252	[0.048-0.066] unit increase	0.05674002	EFO_0007988
ENSG00000171316	rs35440906	8	60733793	CA	Neutrophil percentage of white cells	27863252	[0.055-0.073] unit increase	0.0639525	EFO_0007990
ENSG00000171316	rs35440906	8	60733793	CA	Basophil percentage of white cells	27863252	[0.026-0.043] unit decrease	0.03437348	EFO_0007992
ENSG00000171316	rs7846314	8	60738272	T	White blood cell count	27863252	[0.039-0.057] unit increase	0.04834391	EFO_0004308
ENSG00000171316	rs7846314	8	60738272	T	Monocyte percentage of white cells	27863252	[0.038-0.056] unit decrease	0.04679994	EFO_0007989
ENSG00000171316	rs7846314	8	60738272	T	Neutrophil count	27863252	[0.056-0.074] unit increase	0.06456402	EFO_0004833
ENSG00000171316	rs7846314	8	60738272	T	Neutrophil percentage of granulocytes	27863252	[0.054-0.072] unit increase	0.06265321	EFO_0007994
ENSG00000171316	rs13256023	8	60735992	T	Eosinophil percentage of granulocytes	27863252	[0.048-0.066] unit decrease	0.05694572	EFO_0007996
ENSG00000171316	rs7846314	8	60738272	T	Granulocyte count	27863252	[0.051-0.069] unit increase	0.05996328	EFO_0007987
ENSG00000171316	rs35914442	8	60724328	G	Sum eosinophil basophil counts	27863252	[0.04-0.065] unit decrease	0.05244074	EFO_0005090\|EFO_0004842
ENSG00000171316	rs4449834	8	60843309	T	Sum eosinophil basophil counts	27863252	[0.021-0.037] unit decrease	0.02932891	EFO_0005090\|EFO_0004842
ENSG00000171316	rs7846314	8	60738272	T	Sum neutrophil eosinophil counts	27863252	[0.051-0.069] unit increase	0.06020929	EFO_0004833\|EFO_0004842
ENSG00000171316	rs7846314	8	60738272	T	Sum basophil neutrophil counts	27863252	[0.055-0.073] unit increase	0.06422946	EFO_0004833\|EFO_0005090
ENSG00000171316	rs35440906	8	60733793	CA	Basophil percentage of granulocytes	27863252	[0.034-0.051] unit decrease	0.04250328	EFO_0007995
ENSG00000171316	rs35914442	8	60724328	G	Eosinophil percentage of white cells	27863252	[0.057-0.081] unit decrease	0.06893499	EFO_0007991
ENSG00000171316	rs35914442	8	60724328	G	Eosinophil counts	27863252	[0.038-0.063] unit decrease	0.05059447	EFO_0004842
ENSG00000171316	rs13277976	8	60766479	T	Eosinophil counts	27863252	[0.023-0.04] unit decrease	0.03153353	EFO_0004842
ENSG00000171316	rs4738817	8	60708054	G	Urinary albumin excretion (no hypertensive medication)	30220432	[0.0063-0.0132] unit increase	0.00976	EFO_0004285
ENSG00000171316	rs13269361	8	60694892	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000171316	rs900504	8	60739148	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000171316	rs7846314	8	60738272	?	White blood cell count	30595370			EFO_0004308
ENSG00000171316	rs10094382	8	60860726	?	White blood cell count	30595370			EFO_0004308
ENSG00000171316	rs7842389	8	60772635	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171316's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171316	CHD7	70	79.538	ENSAPOG00000009351	chd7	90	74.660	Acanthochromis_polyacanthus
ENSG00000171316	CHD7	63	69.062	ENSAMEG00000006307	CHD8	60	71.348	Ailuropoda_melanoleuca
ENSG00000171316	CHD7	100	100.000	ENSAMEG00000005699	CHD7	100	96.063	Ailuropoda_melanoleuca
ENSG00000171316	CHD7	55	61.056	ENSACIG00000006440	chd8	60	65.286	Amphilophus_citrinellus
ENSG00000171316	CHD7	70	67.749	ENSACIG00000001590	chd7	91	78.866	Amphilophus_citrinellus
ENSG00000171316	CHD7	67	81.245	ENSAOCG00000002337	chd7	88	81.245	Amphiprion_ocellaris
ENSG00000171316	CHD7	97	64.516	ENSAPEG00000010332	chd7	68	79.696	Amphiprion_percula
ENSG00000171316	CHD7	70	68.632	ENSATEG00000002590	chd7	95	68.937	Anabas_testudineus
ENSG00000171316	CHD7	100	100.000	ENSAPLG00000005873	CHD7	100	92.093	Anas_platyrhynchos
ENSG00000171316	CHD7	60	65.899	ENSACAG00000003139	CHD8	64	68.128	Anolis_carolinensis
ENSG00000171316	CHD7	100	96.875	ENSACAG00000005760	CHD7	100	88.664	Anolis_carolinensis
ENSG00000171316	CHD7	58	69.067	ENSANAG00000037714	CHD8	68	71.307	Aotus_nancymaae
ENSG00000171316	CHD7	100	100.000	ENSANAG00000035300	CHD7	100	98.165	Aotus_nancymaae
ENSG00000171316	CHD7	55	61.587	ENSACLG00000019692	chd8	70	65.947	Astatotilapia_calliptera
ENSG00000171316	CHD7	77	68.447	ENSAMXG00000006180	chd7	98	68.662	Astyanax_mexicanus
ENSG00000171316	CHD7	100	94.872	ENSBTAG00000021841	CHD7	100	91.964	Bos_taurus
ENSG00000171316	CHD7	65	69.133	ENSBTAG00000020422	CHD8	67	71.378	Bos_taurus
ENSG00000171316	CHD7	100	100.000	ENSCJAG00000009025	CHD7	100	98.799	Callithrix_jacchus
ENSG00000171316	CHD7	58	69.133	ENSCJAG00000009002	CHD8	68	71.378	Callithrix_jacchus
ENSG00000171316	CHD7	65	69.133	ENSCAFG00000005626	CHD8	71	71.378	Canis_familiaris
ENSG00000171316	CHD7	100	100.000	ENSCAFG00000007167	CHD7	100	96.503	Canis_familiaris
ENSG00000171316	CHD7	100	100.000	ENSCAFG00020015856	CHD7	100	96.503	Canis_lupus_dingo
ENSG00000171316	CHD7	65	69.133	ENSCAFG00020014565	CHD8	82	75.924	Canis_lupus_dingo
ENSG00000171316	CHD7	57	69.133	ENSCHIG00000026157	CHD8	60	71.429	Capra_hircus
ENSG00000171316	CHD7	100	96.875	ENSCHIG00000011729	CHD7	100	91.354	Capra_hircus
ENSG00000171316	CHD7	100	100.000	ENSTSYG00000004018	CHD7	100	98.167	Carlito_syrichta
ENSG00000171316	CHD7	57	68.833	ENSTSYG00000011939	CHD8	61	71.097	Carlito_syrichta
ENSG00000171316	CHD7	65	58.420	ENSCAPG00000016749	CHD8	58	64.968	Cavia_aperea
ENSG00000171316	CHD7	100	100.000	ENSCAPG00000007952	CHD7	100	92.962	Cavia_aperea
ENSG00000171316	CHD7	100	100.000	ENSCPOG00000013385	CHD7	100	96.231	Cavia_porcellus
ENSG00000171316	CHD7	65	63.364	ENSCPOG00000002538	CHD8	61	71.095	Cavia_porcellus
ENSG00000171316	CHD7	100	100.000	ENSCCAG00000025831	CHD7	100	99.051	Cebus_capucinus
ENSG00000171316	CHD7	58	69.133	ENSCCAG00000020467	CHD8	68	71.378	Cebus_capucinus
ENSG00000171316	CHD7	100	100.000	ENSCATG00000020229	CHD7	100	99.579	Cercocebus_atys
ENSG00000171316	CHD7	58	69.133	ENSCATG00000004861	CHD8	68	71.378	Cercocebus_atys
ENSG00000171316	CHD7	100	100.000	ENSCLAG00000004679	CHD7	100	96.597	Chinchilla_lanigera
ENSG00000171316	CHD7	60	69.000	ENSCLAG00000001966	CHD8	61	71.358	Chinchilla_lanigera
ENSG00000171316	CHD7	57	68.933	ENSCSAG00000016489	CHD8	61	71.216	Chlorocebus_sabaeus
ENSG00000171316	CHD7	100	100.000	ENSCSAG00000014349	CHD7	100	99.300	Chlorocebus_sabaeus
ENSG00000171316	CHD7	55	67.400	ENSCHOG00000003782	CHD8	73	63.456	Choloepus_hoffmanni
ENSG00000171316	CHD7	100	96.875	ENSCHOG00000008478	CHD7	90	94.286	Choloepus_hoffmanni
ENSG00000171316	CHD7	100	96.875	ENSCPBG00000021517	CHD7	100	90.930	Chrysemys_picta_bellii
ENSG00000171316	CHD7	56	68.400	ENSCPBG00000012687	CHD8	67	69.526	Chrysemys_picta_bellii
ENSG00000171316	CHD7	100	100.000	ENSCANG00000041382	CHD7	100	99.579	Colobus_angolensis_palliatus
ENSG00000171316	CHD7	58	69.133	ENSCANG00000042948	CHD8	68	71.378	Colobus_angolensis_palliatus
ENSG00000171316	CHD7	100	100.000	ENSCGRG00001011949	Chd7	100	95.329	Cricetulus_griseus_chok1gshd
ENSG00000171316	CHD7	58	69.082	ENSCGRG00001014351	Chd8	61	71.368	Cricetulus_griseus_chok1gshd
ENSG00000171316	CHD7	58	69.082	ENSCGRG00000009710	Chd8	62	71.368	Cricetulus_griseus_crigri
ENSG00000171316	CHD7	100	100.000	ENSCGRG00000000481	Chd7	100	88.288	Cricetulus_griseus_crigri
ENSG00000171316	CHD7	50	63.844	ENSCSEG00000021155	chd8	66	60.207	Cynoglossus_semilaevis
ENSG00000171316	CHD7	54	62.143	ENSDARG00000075543	chd8	70	63.649	Danio_rerio
ENSG00000171316	CHD7	97	80.645	ENSDARG00000075211	chd7	91	78.426	Danio_rerio
ENSG00000171316	CHD7	57	69.205	ENSDNOG00000005838	CHD8	61	71.510	Dasypus_novemcinctus
ENSG00000171316	CHD7	100	93.750	ENSDNOG00000011674	CHD7	100	92.346	Dasypus_novemcinctus
ENSG00000171316	CHD7	100	100.000	ENSDORG00000003515	Chd7	100	96.530	Dipodomys_ordii
ENSG00000171316	CHD7	62	68.556	ENSETEG00000012353	CHD8	78	72.604	Echinops_telfairi
ENSG00000171316	CHD7	58	97.306	ENSETEG00000016689	-	58	97.280	Echinops_telfairi
ENSG00000171316	CHD7	65	69.067	ENSEASG00005010882	CHD8	76	69.541	Equus_asinus_asinus
ENSG00000171316	CHD7	100	100.000	ENSEASG00005016258	CHD7	100	97.064	Equus_asinus_asinus
ENSG00000171316	CHD7	100	100.000	ENSECAG00000001445	CHD7	100	97.097	Equus_caballus
ENSG00000171316	CHD7	65	69.067	ENSECAG00000016102	CHD8	58	74.498	Equus_caballus
ENSG00000171316	CHD7	100	100.000	ENSEEUG00000013559	CHD7	93	93.395	Erinaceus_europaeus
ENSG00000171316	CHD7	56	60.623	ENSELUG00000004302	chd8	61	64.730	Esox_lucius
ENSG00000171316	CHD7	97	77.419	ENSELUG00000024442	chd7	88	76.305	Esox_lucius
ENSG00000171316	CHD7	66	69.133	ENSFCAG00000013859	CHD8	62	71.429	Felis_catus
ENSG00000171316	CHD7	100	100.000	ENSFCAG00000003849	CHD7	100	94.932	Felis_catus
ENSG00000171316	CHD7	100	100.000	ENSFALG00000005570	CHD7	100	91.391	Ficedula_albicollis
ENSG00000171316	CHD7	58	68.733	ENSFDAG00000011368	CHD8	61	71.216	Fukomys_damarensis
ENSG00000171316	CHD7	100	100.000	ENSFDAG00000000528	CHD7	100	97.571	Fukomys_damarensis
ENSG00000171316	CHD7	54	76.285	ENSGMOG00000004232	chd7	96	76.482	Gadus_morhua
ENSG00000171316	CHD7	50	63.680	ENSGMOG00000015075	chd8	73	64.361	Gadus_morhua
ENSG00000171316	CHD7	100	100.000	ENSGALG00000041080	CHD7	100	91.520	Gallus_gallus
ENSG00000171316	CHD7	70	78.885	ENSGAFG00000006858	chd7	82	79.489	Gambusia_affinis
ENSG00000171316	CHD7	72	66.323	ENSGACG00000014897	chd7	100	66.682	Gasterosteus_aculeatus
ENSG00000171316	CHD7	100	96.875	ENSGAGG00000017996	CHD7	100	89.559	Gopherus_agassizii
ENSG00000171316	CHD7	55	69.156	ENSGAGG00000022951	CHD8	88	70.714	Gopherus_agassizii
ENSG00000171316	CHD7	100	100.000	ENSGGOG00000012224	CHD7	100	100.000	Gorilla_gorilla
ENSG00000171316	CHD7	58	69.133	ENSGGOG00000002251	CHD8	68	71.378	Gorilla_gorilla
ENSG00000171316	CHD7	97	64.516	ENSHBUG00000019225	chd7	84	80.337	Haplochromis_burtoni
ENSG00000171316	CHD7	56	70.617	ENSHGLG00000003559	CHD8	61	71.358	Heterocephalus_glaber_female
ENSG00000171316	CHD7	100	100.000	ENSHGLG00000017268	CHD7	100	96.698	Heterocephalus_glaber_female
ENSG00000171316	CHD7	100	100.000	ENSHGLG00100015649	CHD7	100	96.335	Heterocephalus_glaber_male
ENSG00000171316	CHD7	56	70.617	ENSHGLG00100001031	CHD8	61	71.358	Heterocephalus_glaber_male
ENSG00000171316	CHD7	93	71.503	ENSHCOG00000014380	chd7	88	80.311	Hippocampus_comes
ENSG00000171316	CHD7	76	65.684	ENSIPUG00000007585	chd7	98	65.604	Ictalurus_punctatus
ENSG00000171316	CHD7	100	100.000	ENSSTOG00000011949	CHD7	100	98.601	Ictidomys_tridecemlineatus
ENSG00000171316	CHD7	57	69.000	ENSSTOG00000001854	CHD8	61	71.429	Ictidomys_tridecemlineatus
ENSG00000171316	CHD7	100	97.727	ENSJJAG00000022064	Chd7	100	97.727	Jaculus_jaculus
ENSG00000171316	CHD7	57	69.067	ENSJJAG00000000408	Chd8	61	71.358	Jaculus_jaculus
ENSG00000171316	CHD7	52	64.108	ENSKMAG00000020106	chd8	59	65.393	Kryptolebias_marmoratus
ENSG00000171316	CHD7	97	61.290	ENSKMAG00000009724	chd7	69	79.711	Kryptolebias_marmoratus
ENSG00000171316	CHD7	97	67.742	ENSLBEG00000020842	chd7	69	78.964	Labrus_bergylta
ENSG00000171316	CHD7	100	93.750	ENSLACG00000002461	CHD7	100	82.462	Latimeria_chalumnae
ENSG00000171316	CHD7	100	84.375	ENSLOCG00000005062	chd7	76	79.760	Lepisosteus_oculatus
ENSG00000171316	CHD7	100	100.000	ENSLAFG00000000403	CHD7	100	95.264	Loxodonta_africana
ENSG00000171316	CHD7	57	69.133	ENSLAFG00000009358	CHD8	69	65.273	Loxodonta_africana
ENSG00000171316	CHD7	100	100.000	ENSMFAG00000041825	CHD7	100	99.579	Macaca_fascicularis
ENSG00000171316	CHD7	58	69.133	ENSMFAG00000035402	CHD8	68	71.378	Macaca_fascicularis
ENSG00000171316	CHD7	100	100.000	ENSMMUG00000011584	CHD7	100	99.579	Macaca_mulatta
ENSG00000171316	CHD7	58	69.133	ENSMMUG00000015002	CHD8	68	71.378	Macaca_mulatta
ENSG00000171316	CHD7	100	100.000	ENSMNEG00000040978	CHD7	100	99.476	Macaca_nemestrina
ENSG00000171316	CHD7	58	69.133	ENSMNEG00000031076	CHD8	68	71.378	Macaca_nemestrina
ENSG00000171316	CHD7	100	100.000	ENSMLEG00000038817	CHD7	100	99.579	Mandrillus_leucophaeus
ENSG00000171316	CHD7	58	69.133	ENSMLEG00000035911	CHD8	68	71.378	Mandrillus_leucophaeus
ENSG00000171316	CHD7	84	70.370	ENSMAMG00000011569	chd7	67	79.728	Mastacembelus_armatus
ENSG00000171316	CHD7	53	61.233	ENSMAMG00000016297	chd8	59	65.205	Mastacembelus_armatus
ENSG00000171316	CHD7	97	64.516	ENSMZEG00005010646	chd7	84	80.417	Maylandia_zebra
ENSG00000171316	CHD7	100	100.000	ENSMGAG00000011092	CHD7	100	91.355	Meleagris_gallopavo
ENSG00000171316	CHD7	100	100.000	ENSMAUG00000001000	Chd7	100	94.396	Mesocricetus_auratus
ENSG00000171316	CHD7	60	64.468	ENSMAUG00000015827	Chd8	60	68.475	Mesocricetus_auratus
ENSG00000171316	CHD7	100	100.000	ENSMICG00000002430	CHD7	100	98.427	Microcebus_murinus
ENSG00000171316	CHD7	60	69.133	ENSMICG00000007735	CHD8	68	71.429	Microcebus_murinus
ENSG00000171316	CHD7	60	69.082	ENSMOCG00000013700	Chd8	63	71.368	Microtus_ochrogaster
ENSG00000171316	CHD7	100	100.000	ENSMOCG00000011408	Chd7	100	93.973	Microtus_ochrogaster
ENSG00000171316	CHD7	81	65.385	ENSMMOG00000021538	-	93	53.483	Mola_mola
ENSG00000171316	CHD7	55	61.558	ENSMMOG00000013335	chd8	61	65.529	Mola_mola
ENSG00000171316	CHD7	63	61.939	ENSMODG00000006219	CHD8	75	63.390	Monodelphis_domestica
ENSG00000171316	CHD7	100	100.000	ENSMODG00000008488	CHD7	100	93.873	Monodelphis_domestica
ENSG00000171316	CHD7	50	63.587	ENSMALG00000011572	chd8	61	64.673	Monopterus_albus
ENSG00000171316	CHD7	50	75.683	ENSMALG00000004389	chd7	92	75.823	Monopterus_albus
ENSG00000171316	CHD7	58	69.149	MGP_CAROLIEiJ_G0019237	Chd8	68	71.247	Mus_caroli
ENSG00000171316	CHD7	97	100.000	MGP_CAROLIEiJ_G0025797	Chd7	100	94.630	Mus_caroli
ENSG00000171316	CHD7	58	69.149	ENSMUSG00000053754	Chd8	73	64.815	Mus_musculus
ENSG00000171316	CHD7	100	100.000	ENSMUSG00000041235	Chd7	100	94.663	Mus_musculus
ENSG00000171316	CHD7	58	68.949	MGP_PahariEiJ_G0030258	Chd8	68	71.318	Mus_pahari
ENSG00000171316	CHD7	100	100.000	MGP_PahariEiJ_G0023920	Chd7	100	94.396	Mus_pahari
ENSG00000171316	CHD7	100	100.000	MGP_SPRETEiJ_G0026745	Chd7	100	94.596	Mus_spretus
ENSG00000171316	CHD7	65	69.133	ENSMPUG00000000174	CHD8	61	71.429	Mustela_putorius_furo
ENSG00000171316	CHD7	100	97.436	ENSMPUG00000002338	CHD7	99	96.565	Mustela_putorius_furo
ENSG00000171316	CHD7	57	69.133	ENSMLUG00000001878	CHD8	61	71.429	Myotis_lucifugus
ENSG00000171316	CHD7	100	97.436	ENSMLUG00000015266	CHD7	100	93.796	Myotis_lucifugus
ENSG00000171316	CHD7	60	67.070	ENSNGAG00000022658	Chd8	61	71.298	Nannospalax_galili
ENSG00000171316	CHD7	100	100.000	ENSNGAG00000010767	Chd7	100	98.077	Nannospalax_galili
ENSG00000171316	CHD7	75	64.198	ENSNBRG00000001280	chd7	58	78.118	Neolamprologus_brichardi
ENSG00000171316	CHD7	100	100.000	ENSNLEG00000002027	CHD7	100	99.633	Nomascus_leucogenys
ENSG00000171316	CHD7	58	69.133	ENSNLEG00000014445	CHD8	68	71.429	Nomascus_leucogenys
ENSG00000171316	CHD7	55	64.133	ENSMEUG00000011732	CHD8	72	60.564	Notamacropus_eugenii
ENSG00000171316	CHD7	100	100.000	ENSMEUG00000010045	CHD7	82	92.626	Notamacropus_eugenii
ENSG00000171316	CHD7	54	66.667	ENSOPRG00000016120	CHD8	68	67.365	Ochotona_princeps
ENSG00000171316	CHD7	100	100.000	ENSOPRG00000004404	-	76	100.000	Ochotona_princeps
ENSG00000171316	CHD7	55	68.733	ENSODEG00000001047	CHD8	63	71.216	Octodon_degus
ENSG00000171316	CHD7	100	100.000	ENSODEG00000002424	CHD7	100	96.163	Octodon_degus
ENSG00000171316	CHD7	55	61.649	ENSONIG00000015569	chd8	60	66.134	Oreochromis_niloticus
ENSG00000171316	CHD7	97	64.516	ENSONIG00000016614	chd7	77	68.278	Oreochromis_niloticus
ENSG00000171316	CHD7	100	97.436	ENSOANG00000005042	CHD7	99	92.710	Ornithorhynchus_anatinus
ENSG00000171316	CHD7	81	97.446	ENSOCUG00000010034	CHD7	100	97.446	Oryctolagus_cuniculus
ENSG00000171316	CHD7	97	64.516	ENSORLG00000013492	chd7	68	79.103	Oryzias_latipes
ENSG00000171316	CHD7	53	63.630	ENSORLG00000012103	chd8	67	60.145	Oryzias_latipes
ENSG00000171316	CHD7	97	64.516	ENSORLG00020020002	chd7	67	79.103	Oryzias_latipes_hni
ENSG00000171316	CHD7	97	64.516	ENSORLG00015020858	chd7	68	79.103	Oryzias_latipes_hsok
ENSG00000171316	CHD7	53	63.917	ENSOMEG00000012832	chd8	67	60.462	Oryzias_melastigma
ENSG00000171316	CHD7	97	67.742	ENSOMEG00000016881	chd7	67	78.520	Oryzias_melastigma
ENSG00000171316	CHD7	61	69.133	ENSOGAG00000002722	CHD8	66	71.429	Otolemur_garnettii
ENSG00000171316	CHD7	100	100.000	ENSOGAG00000013905	CHD7	100	97.899	Otolemur_garnettii
ENSG00000171316	CHD7	57	69.087	ENSOARG00000019643	CHD8	60	71.378	Ovis_aries
ENSG00000171316	CHD7	100	96.875	ENSOARG00000016176	CHD7	100	86.724	Ovis_aries
ENSG00000171316	CHD7	57	68.767	ENSPPAG00000039987	CHD8	61	71.027	Pan_paniscus
ENSG00000171316	CHD7	100	100.000	ENSPPAG00000033330	CHD7	100	99.833	Pan_paniscus
ENSG00000171316	CHD7	100	100.000	ENSPPRG00000022248	CHD7	100	95.230	Panthera_pardus
ENSG00000171316	CHD7	65	69.133	ENSPPRG00000006591	CHD8	68	71.378	Panthera_pardus
ENSG00000171316	CHD7	100	100.000	ENSPTIG00000011702	CHD7	99	90.522	Panthera_tigris_altaica
ENSG00000171316	CHD7	65	69.133	ENSPTIG00000021989	CHD8	68	71.378	Panthera_tigris_altaica
ENSG00000171316	CHD7	58	69.133	ENSPTRG00000006124	CHD8	68	71.378	Pan_troglodytes
ENSG00000171316	CHD7	100	100.000	ENSPTRG00000020286	CHD7	100	99.895	Pan_troglodytes
ENSG00000171316	CHD7	58	69.133	ENSPANG00000011742	CHD8	68	71.378	Papio_anubis
ENSG00000171316	CHD7	100	100.000	ENSPANG00000018419	CHD7	100	99.579	Papio_anubis
ENSG00000171316	CHD7	53	64.162	ENSPKIG00000009142	chd8	60	65.337	Paramormyrops_kingsleyae
ENSG00000171316	CHD7	100	78.125	ENSPKIG00000009637	chd7	76	75.986	Paramormyrops_kingsleyae
ENSG00000171316	CHD7	100	96.875	ENSPSIG00000012003	CHD7	100	91.205	Pelodiscus_sinensis
ENSG00000171316	CHD7	76	64.809	ENSPMGG00000018543	chd7	97	64.955	Periophthalmus_magnuspinnatus
ENSG00000171316	CHD7	100	100.000	ENSPEMG00000023028	Chd7	100	93.671	Peromyscus_maniculatus_bairdii
ENSG00000171316	CHD7	58	69.082	ENSPEMG00000022977	Chd8	61	71.368	Peromyscus_maniculatus_bairdii
ENSG00000171316	CHD7	100	100.000	ENSPCIG00000000025	-	100	92.806	Phascolarctos_cinereus
ENSG00000171316	CHD7	65	68.386	ENSPCIG00000020931	CHD8	80	72.656	Phascolarctos_cinereus
ENSG00000171316	CHD7	72	78.807	ENSPFOG00000004891	chd7	92	83.544	Poecilia_formosa
ENSG00000171316	CHD7	52	64.507	ENSPFOG00000016369	chd8	66	60.656	Poecilia_formosa
ENSG00000171316	CHD7	71	78.807	ENSPLAG00000023322	chd7	68	79.250	Poecilia_latipinna
ENSG00000171316	CHD7	52	64.555	ENSPREG00000021867	chd8	59	65.786	Poecilia_reticulata
ENSG00000171316	CHD7	51	77.414	ENSPREG00000014744	chd7	96	73.541	Poecilia_reticulata
ENSG00000171316	CHD7	100	100.000	ENSPPYG00000018618	CHD7	100	99.700	Pongo_abelii
ENSG00000171316	CHD7	57	69.133	ENSPPYG00000005596	CHD8	61	71.429	Pongo_abelii
ENSG00000171316	CHD7	90	94.789	ENSPCAG00000000227	CHD7	92	94.789	Procavia_capensis
ENSG00000171316	CHD7	58	68.182	ENSPCOG00000014628	CHD8	61	70.391	Propithecus_coquereli
ENSG00000171316	CHD7	100	100.000	ENSPCOG00000013850	CHD7	100	98.840	Propithecus_coquereli
ENSG00000171316	CHD7	65	69.200	ENSPVAG00000000272	CHD8	66	70.755	Pteropus_vampyrus
ENSG00000171316	CHD7	100	97.436	ENSPVAG00000011873	CHD7	95	95.873	Pteropus_vampyrus
ENSG00000171316	CHD7	74	65.441	ENSPNYG00000012490	chd7	92	75.222	Pundamilia_nyererei
ENSG00000171316	CHD7	72	69.658	ENSPNAG00000011245	chd7	98	69.846	Pygocentrus_nattereri
ENSG00000171316	CHD7	51	64.485	ENSPNAG00000003683	chd8	60	65.275	Pygocentrus_nattereri
ENSG00000171316	CHD7	58	69.149	ENSRNOG00000025011	Chd8	70	65.494	Rattus_norvegicus
ENSG00000171316	CHD7	100	100.000	ENSRNOG00000006689	Chd7	100	94.167	Rattus_norvegicus
ENSG00000171316	CHD7	100	100.000	ENSRBIG00000043575	CHD7	100	99.579	Rhinopithecus_bieti
ENSG00000171316	CHD7	57	64.977	ENSRBIG00000039239	CHD8	67	67.279	Rhinopithecus_bieti
ENSG00000171316	CHD7	58	69.133	ENSRROG00000044285	CHD8	68	71.378	Rhinopithecus_roxellana
ENSG00000171316	CHD7	100	100.000	ENSRROG00000008981	CHD7	100	99.473	Rhinopithecus_roxellana
ENSG00000171316	CHD7	100	100.000	ENSSBOG00000021462	CHD7	100	98.932	Saimiri_boliviensis_boliviensis
ENSG00000171316	CHD7	57	69.133	ENSSBOG00000023442	CHD8	61	71.429	Saimiri_boliviensis_boliviensis
ENSG00000171316	CHD7	66	68.600	ENSSHAG00000008118	CHD8	61	70.231	Sarcophilus_harrisii
ENSG00000171316	CHD7	100	100.000	ENSSHAG00000011522	CHD7	100	93.804	Sarcophilus_harrisii
ENSG00000171316	CHD7	52	61.481	ENSSFOG00015011577	chd8	61	62.276	Scleropages_formosus
ENSG00000171316	CHD7	100	84.375	ENSSFOG00015015077	chd7	75	78.932	Scleropages_formosus
ENSG00000171316	CHD7	61	66.873	ENSSMAG00000001453	-	78	62.624	Scophthalmus_maximus
ENSG00000171316	CHD7	51	64.295	ENSSMAG00000014060	chd8	68	59.806	Scophthalmus_maximus
ENSG00000171316	CHD7	97	64.516	ENSSMAG00000001030	chd7	87	64.639	Scophthalmus_maximus
ENSG00000171316	CHD7	55	61.687	ENSSDUG00000012439	chd8	60	65.441	Seriola_dumerili
ENSG00000171316	CHD7	55	61.697	ENSSLDG00000001679	chd8	59	65.810	Seriola_lalandi_dorsalis
ENSG00000171316	CHD7	84	70.370	ENSSLDG00000022595	chd7	90	55.665	Seriola_lalandi_dorsalis
ENSG00000171316	CHD7	100	97.436	ENSSARG00000003387	CHD7	87	96.364	Sorex_araneus
ENSG00000171316	CHD7	63	65.602	ENSSARG00000004849	CHD8	73	67.630	Sorex_araneus
ENSG00000171316	CHD7	100	100.000	ENSSPUG00000009235	CHD7	100	90.588	Sphenodon_punctatus
ENSG00000171316	CHD7	53	63.447	ENSSPAG00000022956	chd8	60	64.854	Stegastes_partitus
ENSG00000171316	CHD7	72	78.785	ENSSPAG00000006320	chd7	91	79.585	Stegastes_partitus
ENSG00000171316	CHD7	65	69.133	ENSSSCG00000002127	CHD8	64	71.429	Sus_scrofa
ENSG00000171316	CHD7	100	100.000	ENSSSCG00000006231	CHD7	100	93.696	Sus_scrofa
ENSG00000171316	CHD7	100	100.000	ENSTGUG00000011196	CHD7	100	91.162	Taeniopygia_guttata
ENSG00000171316	CHD7	64	82.206	ENSTRUG00000008632	chd7	90	76.277	Takifugu_rubripes
ENSG00000171316	CHD7	64	70.753	ENSTNIG00000002647	chd7	83	77.270	Tetraodon_nigroviridis
ENSG00000171316	CHD7	100	100.000	ENSTBEG00000001540	CHD7	91	94.631	Tupaia_belangeri
ENSG00000171316	CHD7	100	96.875	ENSTTRG00000004221	CHD7	97	92.175	Tursiops_truncatus
ENSG00000171316	CHD7	57	68.667	ENSTTRG00000016076	CHD8	68	70.883	Tursiops_truncatus
ENSG00000171316	CHD7	57	74.026	ENSUAMG00000004198	CHD8	97	73.985	Ursus_americanus
ENSG00000171316	CHD7	100	100.000	ENSUAMG00000025734	CHD7	100	94.995	Ursus_americanus
ENSG00000171316	CHD7	100	100.000	ENSUMAG00000010436	CHD7	100	96.910	Ursus_maritimus
ENSG00000171316	CHD7	66	69.133	ENSUMAG00000004045	CHD8	79	73.910	Ursus_maritimus
ENSG00000171316	CHD7	100	97.436	ENSVPAG00000009756	-	61	100.000	Vicugna_pacos
ENSG00000171316	CHD7	65	69.133	ENSVVUG00000009444	CHD8	64	71.429	Vulpes_vulpes
ENSG00000171316	CHD7	100	100.000	ENSVVUG00000018063	CHD7	100	95.329	Vulpes_vulpes
ENSG00000171316	CHD7	51	62.399	ENSXETG00000017194	CHD8	87	73.428	Xenopus_tropicalis
ENSG00000171316	CHD7	98	83.000	ENSXETG00000026004	chd8	78	85.472	Xenopus_tropicalis
ENSG00000171316	CHD7	97	58.065	ENSXMAG00000018590	chd7	68	79.409	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	-	IEA	Function
GO:0001501	skeletal system development	16155193.	IMP	Process
GO:0001701	in utero embryonic development	15300250.	IMP	Process
GO:0001974	blood vessel remodeling	-	IEA	Process
GO:0003007	heart morphogenesis	15300250.	IMP	Process
GO:0003222	ventricular trabecula myocardium morphogenesis	-	IEA	Process
GO:0003226	right ventricular compact myocardium morphogenesis	-	IEA	Process
GO:0003682	chromatin binding	17299439.	TAS	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	20130577.20453063.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	20453063.	IDA	Component
GO:0005634	nucleus	17299439.	TAS	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006338	chromatin remodeling	-	IEA	Process
GO:0006355	regulation of transcription, DNA-templated	17937444.	NAS	Process
GO:0006364	rRNA processing	-	IEA	Process
GO:0007417	central nervous system development	9556299.	IMP	Process
GO:0007512	adult heart development	-	IEA	Process
GO:0007605	sensory perception of sound	-	IEA	Process
GO:0007628	adult walking behavior	-	IEA	Process
GO:0008015	blood circulation	-	IEA	Process
GO:0009617	response to bacterium	-	IEA	Process
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	-	IEA	Process
GO:0021545	cranial nerve development	9556299.	IMP	Process
GO:0021553	olfactory nerve development	-	IEA	Process
GO:0021772	olfactory bulb development	-	IEA	Process
GO:0030217	T cell differentiation	17684005.	IMP	Process
GO:0030540	female genitalia development	-	IEA	Process
GO:0035116	embryonic hindlimb morphogenesis	-	IEA	Process
GO:0035909	aorta morphogenesis	-	IEA	Process
GO:0036302	atrioventricular canal development	-	IEA	Process
GO:0040018	positive regulation of multicellular organism growth	-	IEA	Process
GO:0042048	olfactory behavior	-	IEA	Process
GO:0042472	inner ear morphogenesis	15300250.	IMP	Process
GO:0043584	nose development	15300250.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0048752	semicircular canal morphogenesis	-	IEA	Process
GO:0048806	genitalia development	15300250.	IMP	Process
GO:0050767	regulation of neurogenesis	-	IEA	Process
GO:0050890	cognition	16155193.	IMP	Process
GO:0060041	retina development in camera-type eye	15300250.	IMP	Process
GO:0060123	regulation of growth hormone secretion	9556299.	IMP	Process
GO:0060173	limb development	17937444.	IMP	Process
GO:0060324	face development	15300250.	IMP	Process
GO:0060384	innervation	-	IEA	Process
GO:0060411	cardiac septum morphogenesis	-	IEA	Process
GO:0060429	epithelium development	-	IEA	Process
GO:0062009	secondary palate development	15300250.	IMP	Process
GO:1990841	promoter-specific chromatin binding	-	IEA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28007623	Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).	J Thorac Oncol	2017 Apr	Augert A	doi: 10.1016/j.jtho.2016.12.011
28649742	Genotranscriptomic meta-analysis of the CHD family chromatin remodelers in human cancers - initial evidence of an oncogenic role for CHD7.	Mol Oncol	2017 Oct	Chu X	doi: 10.1002/1878-0261.12104

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr8	60853478	Silent	rs755202253	S2251S	0.83
ACC	chr8	60830496	Missense_Mutation	rs190548814	G1233S	0.29
ACC	chr8	60856758	Missense_Mutation	novel	P2493R	0.55
ACC	chr8	60741877	Missense_Mutation	novel	A149S	0.49
ACC	chr8	60853101	Missense_Mutation	novel	D2126H	0.44
BLCA	chr8	60865387	Silent	novel	L2816L	0.27
BLCA	chr8	60853379	Silent	novel	L2218L	0.32
BLCA	chr8	60742826	Missense_Mutation	NA	S465Y	0.2
BLCA	chr8	60822505	Missense_Mutation	rs767390470	R987Q	0.12
BLCA	chr8	60741431	5'UTR	NA		0.2
BLCA	chr8	60852501	Missense_Mutation	NA	W1966C	0.23
BLCA	chr8	60822586	Missense_Mutation	NA	G1014E	0.07
BLCA	chr8	60836899	Missense_Mutation	NA	D1358N	0.2
BLCA	chr8	60741757	Missense_Mutation	novel	P109T	0.43
BLCA	chr8	60841940	Missense_Mutation	novel	E1580K	0.22
BLCA	chr8	60836072	Splice_Site	novel	X1260_splice	0.22
BLCA	chr8	60824094	Intron	novel		0.08
BLCA	chr8	60742096	Missense_Mutation	novel	Q222E	0.2
BLCA	chr8	60742224	Silent	novel	L264L	0.14
BLCA	chr8	60836897	Missense_Mutation	novel	S1357C	0.29
BLCA	chr8	60781183	Missense_Mutation	novel	K617E	0.53	ResIII
BLCA	chr8	60830511	Missense_Mutation	rs794727150	V1238I	0.23
BLCA	chr8	60853198	Missense_Mutation	rs376056567	S2158L	0.37
BLCA	chr8	60853154	Silent	novel	L2143L	0.44
BLCA	chr8	60742187	Missense_Mutation	rs371930390	S252L	0.25
BLCA	chr8	60823891	Missense_Mutation	novel	E1085Q	0.14
BLCA	chr8	60837757	Silent	rs368919638	F1425F	0.41
BLCA	chr8	60836938	Missense_Mutation	NA	L1371V	0.27
BLCA	chr8	60742036	Nonsense_Mutation	novel	Q202*	0.31
BLCA	chr8	60848554	Silent	novel	Q1750Q	0.35
BLCA	chr8	60854495	Missense_Mutation	novel	R2303K	0.12
BLCA	chr8	60841872	Missense_Mutation	novel	R1557K	0.25
BLCA	chr8	60800427	Missense_Mutation	novel	T760A	0.51
BLCA	chr8	60824035	Intron	novel		0.12
BLCA	chr8	60743029	Missense_Mutation	novel	H533N	0.18
BLCA	chr8	60853080	Missense_Mutation	novel	D2119N	0.54
BLCA	chr8	60856649	Missense_Mutation	NA	N2457Y	0.2
BLCA	chr8	60861018	Missense_Mutation	novel	E2575Q	0.25
BLCA	chr8	60836135	Nonsense_Mutation	NA	Q1281*	0.53
BLCA	chr8	60823862	Missense_Mutation	rs759929302	Y1075C	0.1
BLCA	chr8	60853493	Silent	novel	Q2256Q	0.07
BLCA	chr8	60741466	Missense_Mutation	rs769949098	E12K	0.67
BLCA	chr8	60865579	Silent	rs374937585	P2880P	0.12
BLCA	chr8	60741613	Missense_Mutation	novel	Q61E	0.28
BLCA	chr8	60742660	Missense_Mutation	rs763637398	P410S	0.25
BLCA	chr8	60861017	Silent	novel	L2574L	0.17
BLCA	chr8	60848530	Silent	novel	V1742V	0.4
BLCA	chr8	60852567	Silent	novel	V1988V	0.31
BLCA	chr8	60742383	Missense_Mutation	NA	N317K	0.17
BRCA	chr8	60856829	Missense_Mutation	novel	K2517E	0.17
BRCA	chr8	60856750	Silent	novel	S2490S	0.05
BRCA	chr8	60850528	Missense_Mutation	rs368609862	A1814T	0.3
BRCA	chr8	60853296	Missense_Mutation	NA	E2191Q	0.2
BRCA	chr8	60856464	Missense_Mutation	novel	S2395Y	0.11
BRCA	chr8	60861026	Silent	NA	G2577G	0.46
BRCA	chr8	60781311	Silent	NA	P659P	0.15
BRCA	chr8	60861051	Missense_Mutation	NA	P2586S	0.28
BRCA	chr8	60852986	Silent	NA	L2087L	0.12
BRCA	chr8	60741320	5'UTR	novel		0.27
BRCA	chr8	60742364	Missense_Mutation	novel	S311F	0.14
BRCA	chr8	60741400	5'UTR	novel		0.09
BRCA	chr8	60841721	Missense_Mutation	novel	K1537N	0.09
BRCA	chr8	60841862	Missense_Mutation	novel	D1554Y	0.09
BRCA	chr8	60861077	Nonsense_Mutation	novel	W2594*	0.06
BRCA	chr8	60741613	Missense_Mutation	novel	Q61E	0.21
BRCA	chr8	60865321	Silent	NA	A2794A	0.45
BRCA	chr8	60781207	Missense_Mutation	NA	D625H	0.15	ResIII
BRCA	chr8	60849149	Missense_Mutation	novel	K1800T	0.06
BRCA	chr8	60854464	Missense_Mutation	novel	D2293Y	0.05
BRCA	chr8	60853254	Missense_Mutation	rs750047137	E2177K	0.1
BRCA	chr8	60741613	Nonsense_Mutation	novel	Q61*	0.27
BRCA	chr8	60865600	Silent	rs148517660	P2887P	0.33
BRCA	chr8	60741655	Missense_Mutation	NA	Y75H	0.38
BRCA	chr8	60866694	3'UTR	novel		0.29
BRCA	chr8	60853464	Missense_Mutation	NA	D2247Y	0.44
BRCA	chr8	60865035	Missense_Mutation	NA	M2699K	0.62
BRCA	chr8	60742969	Missense_Mutation	NA	T513S	0.18
BRCA	chr8	60741647	Missense_Mutation	rs767819417	Y72C	0.23
BRCA	chr8	60816475	In_Frame_Del	novel	G864_Q865del	0.42
BRCA	chr8	60853201	Missense_Mutation	novel	S2159C	0.12
CESC	chr8	60865127	Missense_Mutation	rs757707495	A2730T	0.26
CESC	chr8	60854495	Missense_Mutation	novel	R2303T	0.31
CESC	chr8	60823968	Silent	novel	L1110L	0.22
CESC	chr8	60856623	Nonsense_Mutation	novel	S2448*	0.27
CESC	chr8	60865528	Silent	NA	A2863A	0.24
CESC	chr8	60852700	Missense_Mutation	NA	D2033H	0.26
CESC	chr8	60822689	Silent	novel	G1048G	0.42
CESC	chr8	60856484	Missense_Mutation	NA	R2402G	0.23
CESC	chr8	60862315	Silent	novel	V2650V	0.24
CESC	chr8	60838112	Missense_Mutation	novel	L1464V	0.23
CESC	chr8	60822505	Missense_Mutation	rs767390470	R987Q	0.26
CESC	chr8	60741506	Missense_Mutation	NA	G25E	0.24
CESC	chr8	60853312	Missense_Mutation	NA	T2196I	0.24
CESC	chr8	60781037	Missense_Mutation	rs757689264	P568L	0.23
CESC	chr8	60852580	Missense_Mutation	NA	D1993H	0.16
CESC	chr8	60742633	Missense_Mutation	novel	A401T	0.14
CESC	chr8	60823859	Missense_Mutation	novel	S1074Y	0.22
CESC	chr8	60742808	Missense_Mutation	rs563490827	R459H	0.39
CESC	chr8	60845312	Missense_Mutation	novel	P1705S	0.41
CESC	chr8	60848568	Missense_Mutation	novel	D1755G	0.35
CESC	chr8	60852682	Nonsense_Mutation	NA	R2027*	0.41
CESC	chr8	60865813	Silent	rs377755006	A2958A	0.29
CESC	chr8	60866277	3'UTR	novel		0.32
CESC	chr8	60823870	Missense_Mutation	NA	H1078Y	0.24
CESC	chr8	60743075	Missense_Mutation	rs778361949	P548L	0.24
CESC	chr8	60853305	Missense_Mutation	novel	E2194K	0.23
CESC	chr8	60781131	Missense_Mutation	novel	K599N	0.49	ResIII
CESC	chr8	60742732	Nonsense_Mutation	novel	Q434*	0.33
CESC	chr8	60851283	Missense_Mutation	novel	E1877Q	0.19
CESC	chr8	60795110	Missense_Mutation	NA	E741K	0.23
CESC	chr8	60837687	Missense_Mutation	NA	R1402T	0.22
CESC	chr8	60838154	Missense_Mutation	NA	E1478K	0.45
CESC	chr8	60741933	Silent	rs770348243	P167P	0.23
CESC	chr8	60866743	3'UTR	novel		0.42
CHOL	chr8	60742912	Nonsense_Mutation	rs587783429	R494*	0.26
CHOL	chr8	60816388	Frame_Shift_Del	novel	*Y835Sfs14**	0.43
CHOL	chr8	60741890	Missense_Mutation	novel	P153Q	0.32
CHOL	chr8	60856196	Missense_Mutation	novel	L2386F	0.13
CHOL	chr8	60852895	Missense_Mutation	novel	R2057H	0.07
COAD	chr8	60830562	Missense_Mutation	rs764970349	P1255S	0.34
COAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.24
COAD	chr8	60861054	Frame_Shift_Del	novel	*N2588Ifs4**	0.14
COAD	chr8	60850597	Missense_Mutation	novel	D1837N	0.05
COAD	chr8	60742500	Silent	NA	N356N	0.09
COAD	chr8	60862259	Missense_Mutation	NA	N2632H	0.2
COAD	chr8	60856030	Missense_Mutation	rs747050794	K2331R	0.38
COAD	chr8	60824035	Intron	novel		0.31
COAD	chr8	60865900	Silent	novel	G2987G	0.28
COAD	chr8	60743052	Silent	novel	L540L	0.18
COAD	chr8	60742367	Missense_Mutation	NA	R312Q	0.06
COAD	chr8	60830334	Missense_Mutation	novel	Q1179K	0.1
COAD	chr8	60856751	Missense_Mutation	rs755492299	R2491C	0.07
COAD	chr8	60742662	Silent	novel	P410P	0.5
COAD	chr8	60853418	Silent	NA	S2231S	0.17
COAD	chr8	60856774	Silent	novel	L2498L	0.24
COAD	chr8	60741933	Silent	rs770348243	P167P	0.55
COAD	chr8	60741505	Missense_Mutation	rs759887905	G25R	0.53
COAD	chr8	60816500	Missense_Mutation	novel	E871G	0.34
COAD	chr8	60781301	Missense_Mutation	rs776871277	P656L	0.36
COAD	chr8	60742563	Silent	novel	N377N	0.28
COAD	chr8	60841733	Silent	rs754019726	D1541D	0.6
COAD	chr8	60816460	Nonsense_Mutation	NA	R858*	0.27
COAD	chr8	60852096	Silent	novel	R1915R	0.24
COAD	chr8	60742547	Nonsense_Mutation	novel	S372*	0.17
COAD	chr8	60853077	Missense_Mutation	NA	N2118D	0.3
COAD	chr8	60852847	Missense_Mutation	NA	S2041F	0.18
COAD	chr8	60850491	Splice_Site	NA	X1802_splice	0.23
COAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.36
COAD	chr8	60816461	Missense_Mutation	NA	R858Q	0.31
COAD	chr8	60742160	Missense_Mutation	novel	P243H	0.1
COAD	chr8	60742893	Missense_Mutation	novel	D487E	0.09
COAD	chr8	60742521	Silent	novel	H363H	0.34
COAD	chr8	60821842	Missense_Mutation	NA	T917M	0.2
COAD	chr8	60781281	Frame_Shift_Del	NA	*D652Tfs59**	0.27
COAD	chr8	60837675	Missense_Mutation	novel	A1398V	0.08
COAD	chr8	60850492	Splice_Site	NA	X1802_splice	0.19
COAD	chr8	60853012	Missense_Mutation	NA	H2096L	0.15
COAD	chr8	60781281	Frame_Shift_Del	NA	*D652Tfs59**	0.3
COAD	chr8	60865742	Missense_Mutation	rs745944842	E2935K	0.18
COAD	chr8	60741745	Missense_Mutation	novel	Y105H	0.44
COAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.38
COAD	chr8	60842013	Missense_Mutation	novel	S1604N	0.09
COAD	chr8	60800449	Missense_Mutation	novel	I767S	0.1
COAD	chr8	60836938	Missense_Mutation	NA	L1371V	0.17
COAD	chr8	60837757	Silent	rs368919638	F1425F	0.15
COAD	chr8	60841977	Missense_Mutation	NA	R1592Q	0.22
COAD	chr8	60856478	Missense_Mutation	rs770959300	R2400W	0.19
COAD	chr8	60856652	Missense_Mutation	NA	F2458V	0.18
COAD	chr8	60742022	Frame_Shift_Ins	novel	*S199Ffs88**	0.3
COAD	chr8	60838200	Missense_Mutation	NA	R1493H	0.58
COAD	chr8	60742442	Missense_Mutation	novel	N337T	0.32
COAD	chr8	60781142	Missense_Mutation	NA	N603S	0.4	ResIII
COAD	chr8	60822504	Nonsense_Mutation	NA	R987*	0.42
COAD	chr8	60836906	Missense_Mutation	NA	F1360C	0.45
COAD	chr8	60841650	Missense_Mutation	NA	F1514V	0.34
COAD	chr8	60781156	Missense_Mutation	novel	A608T	0.1	ResIII
COAD	chr8	60865078	Silent	novel	G2713G	0.12
COAD	chr8	60742998	Silent	rs759347960	G522G	0.39
COAD	chr8	60856749	Missense_Mutation	rs371595770	S2490L	0.34
COAD	chr8	60742219	Missense_Mutation	novel	A263T	0.23
COAD	chr8	60836872	Missense_Mutation	novel	I1349V	0.29
COAD	chr8	60841717	Missense_Mutation	NA	K1536R	0.2
COAD	chr8	60853498	Missense_Mutation	NA	E2258G	0.35
COAD	chr8	60830473	Missense_Mutation	NA	N1225S	0.39
COAD	chr8	60822599	Frame_Shift_Del	NA	L1020*	0.09
COAD	chr8	60853406	Frame_Shift_Ins	novel	*G2228Lfs52**	0.03
COAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.15
COAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.36
COAD	chr8	60742947	Silent	NA	Q505Q	0.27
COAD	chr8	60850608	Silent	novel	A1840A	0.28
COAD	chr8	60852181	Missense_Mutation	rs753723769	R1943Q	0.09
COAD	chr8	60836867	Missense_Mutation	novel	A1347V	0.38
COAD	chr8	60856167	Missense_Mutation	novel	S2377G	0.26
DLBC	chr8	60801558	Frame_Shift_Ins	novel	*I805Nfs20**	0.24
DLBC	chr8	60741296	5'UTR	novel		0.14
ESCA	chr8	60852537	Silent	novel	V1978V	0.58
ESCA	chr8	60742390	Missense_Mutation	novel	Q320E	0.09
ESCA	chr8	60838154	Missense_Mutation	NA	E1478K	0.3
ESCA	chr8	60865447	Silent	novel	P2836P	0.34
ESCA	chr8	60865552	Silent	novel	N2871N	0.2
ESCA	chr8	60865330	Silent	novel	P2797P	0.36
ESCA	chr8	60850498	Missense_Mutation	novel	E1804K	0.1
GBM	chr8	60856750	Silent	rs780608336	S2490S	0.4
GBM	chr8	60862290	Missense_Mutation	novel	T2642I	0.24
GBM	chr8	60742840	Missense_Mutation	novel	E470K	0.38
GBM	chr8	60742609	Missense_Mutation	novel	P393A	0.04
GBM	chr8	60841872	Missense_Mutation	novel	R1557I	0.08
GBM	chr8	60741686	Missense_Mutation	novel	Q85L	0.06
GBM	chr8	60856549	Missense_Mutation	novel	M2423I	0.05
GBM	chr8	60742403	Missense_Mutation	novel	N324S	0.11
GBM	chr8	60853436	Silent	rs370385319	S2237S	0.53
GBM	chr8	60742648	Frame_Shift_Del	novel	*A406Qfs57**	0.12
GBM	chr8	60852136	Missense_Mutation	NA	Q1928L	0.33
HNSC	chr8	60856750	Silent	rs780608336	S2490S	0.16
HNSC	chr8	60865814	Missense_Mutation	rs774166245	E2959K	0.16
HNSC	chr8	60865458	Missense_Mutation	novel	T2840S	0.26
HNSC	chr8	60865115	Missense_Mutation	rs749452262	A2726T	0.21
HNSC	chr8	60865742	Missense_Mutation	rs745944842	E2935K	0.24
HNSC	chr8	60742604	Missense_Mutation	novel	A391V	0.32
HNSC	chr8	60852628	Missense_Mutation	novel	E2009K	0.28
HNSC	chr8	60828695	Silent	novel	L1137L	0.36
HNSC	chr8	60800425	Missense_Mutation	novel	Y759F	0.16
HNSC	chr8	60741734	Missense_Mutation	rs769161426	P101L	0.23
HNSC	chr8	60795061	Missense_Mutation	novel	N724K	0.32
HNSC	chr8	60865621	Silent	rs780047697	L2894L	0.19
HNSC	chr8	60853287	Missense_Mutation	novel	E2188Q	0.3
HNSC	chr8	60853150	Missense_Mutation	NA	S2142F	0.63
HNSC	chr8	60862248	Missense_Mutation	rs777577551	H2628R	0.37
HNSC	chr8	60830507	Frame_Shift_Del	novel	*N1237Ifs15**	0.17
HNSC	chr8	60853018	Missense_Mutation	rs375199214	R2098Q	0.36
HNSC	chr8	60844880	Missense_Mutation	novel	D1623H	0.17
HNSC	chr8	60823947	Silent	novel	V1103V	0.1
HNSC	chr8	60853313	Silent	rs746103884	T2196T	0.12
HNSC	chr8	60853016	Silent	novel	D2097D	0.38
HNSC	chr8	60836180	Missense_Mutation	novel	D1296H	0.38
HNSC	chr8	60852078	Missense_Mutation	novel	L1909M	0.43
HNSC	chr8	60823954	Missense_Mutation	novel	E1106K	0.22
HNSC	chr8	60852137	Silent	novel	Q1928Q	0.14
KICH	chr8	60853483	Missense_Mutation	novel	E2253G	0.23
KIRC	chr8	60849130	Missense_Mutation	NA	L1794I	0.24
KIRC	chr8	60856009	Missense_Mutation	NA	C2324Y	0.23
KIRC	chr8	60845305	Silent	NA	S1702S	0.17
KIRC	chr8	60856675	Silent	NA	F2465F	0.23
KIRC	chr8	60781418	Frame_Shift_Ins	novel	*K696Efs25**	0.07
KIRC	chr8	60861086	Silent	novel	L2597L	0.14
KIRC	chr8	60862257	Missense_Mutation	NA	R2631Q	0.06
KIRC	chr8	60865389	Missense_Mutation	NA	N2817S	0.22
KIRC	chr8	60842025	Missense_Mutation	NA	R1608K	0.33
KIRP	chr8	60865910	Missense_Mutation	novel	E2991K	0.42
KIRP	chr8	60795025	Silent	novel	K712K	0.07
KIRP	chr8	60742203	Silent	NA	H257H	0.39
LAML	chr8	60865577	Missense_Mutation	novel	P2880T	0.08
LGG	chr8	60741496	Missense_Mutation	NA	E22Q	0.5
LGG	chr8	60800485	Missense_Mutation	novel	G779V	0.07
LGG	chr8	60741600	Silent	rs199776087	H56H	0.17
LIHC	chr8	60741346	5'UTR	novel		0.45
LIHC	chr8	60836879	Missense_Mutation	NA	R1351K	0.44
LIHC	chr8	60853341	Nonsense_Mutation	novel	E2206*	0.28
LIHC	chr8	60824021	Splice_Region	novel		0.24
LIHC	chr8	60853036	Missense_Mutation	NA	A2104V	0.46
LIHC	chr8	60856693	Silent	NA	S2471S	0.5
LIHC	chr8	60781212	Missense_Mutation	NA	N626K	0.24	ResIII
LIHC	chr8	60853076	Silent	novel	L2117L	0.27
LIHC	chr8	60852195	Missense_Mutation	NA	V1948M	0.42
LIHC	chr8	60741748	Missense_Mutation	NA	H106Y	0.25
LUAD	chr8	60865198	Missense_Mutation	novel	M2753I	0.19
LUAD	chr8	60742367	Missense_Mutation	NA	R312Q	0.26
LUAD	chr8	60865265	Missense_Mutation	rs773045619	P2776S	0.33
LUAD	chr8	60862249	Silent	NA	H2628H	0.17
LUAD	chr8	60853097	Silent	novel	F2124F	0.26
LUAD	chr8	60862268	Nonsense_Mutation	NA	K2635*	0.44
LUAD	chr8	60741647	Missense_Mutation	rs767819417	Y72C	0.2
LUAD	chr8	60862256	Nonsense_Mutation	rs587783457	R2631*	0.14
LUAD	chr8	60845379	Missense_Mutation	novel	Y1727C	0.44
LUAD	chr8	60836178	Missense_Mutation	NA	I1295N	0.4
LUAD	chr8	60853136	Silent	novel	A2137A	0.22
LUAD	chr8	60853374	Nonsense_Mutation	novel	E2217*	0.4
LUAD	chr8	60822042	Missense_Mutation	NA	D952N	0.25
LUAD	chr8	60841934	Missense_Mutation	NA	D1578N	0.14
LUAD	chr8	60824120	Intron	novel		0.33
LUAD	chr8	60822631	Missense_Mutation	NA	P1029L	0.29
LUAD	chr8	60865068	Missense_Mutation	NA	R2710L	0.28
LUAD	chr8	60742504	Missense_Mutation	rs745778752	G358C	0.27
LUAD	chr8	60854378	Missense_Mutation	NA	R2264K	0.09
LUAD	chr8	60862212	Missense_Mutation	NA	L2616R	0.42
LUAD	chr8	60856843	Silent	novel	G2521G	0.27
LUAD	chr8	60828719	Silent	novel	F1145F	0.33
LUAD	chr8	60849058	Missense_Mutation	rs762824174	D1770N	0.15
LUAD	chr8	60822559	Missense_Mutation	NA	T1005R	0.32
LUAD	chr8	60742958	Missense_Mutation	novel	Q509L	0.49
LUAD	chr8	60742824	Missense_Mutation	rs780392912	M464I	0.25
LUAD	chr8	60837681	Missense_Mutation	novel	C1400Y	0.38
LUAD	chr8	60865562	Missense_Mutation	NA	G2875C	0.63
LUAD	chr8	60836245	Silent	NA	R1317R	0.06
LUAD	chr8	60856589	Nonsense_Mutation	novel	G2437*	0.6
LUAD	chr8	60856590	Missense_Mutation	novel	G2437V	0.62
LUAD	chr8	60795001	Silent	NA	D704D	0.17
LUAD	chr8	60853461	Nonsense_Mutation	novel	E2246*	0.13
LUAD	chr8	60741869	Missense_Mutation	NA	G146V	0.61
LUAD	chr8	60836195	Missense_Mutation	NA	K1301E	0.59
LUAD	chr8	60742995	Silent	rs765356585	P521P	0.27
LUAD	chr8	60741635	Missense_Mutation	rs771073528	H68R	0.47
LUAD	chr8	60842012	Missense_Mutation	NA	S1604C	0.13
LUAD	chr8	60822110	Missense_Mutation	NA	E974D	0.28
LUSC	chr8	60816475	Nonsense_Mutation	novel	Q863*	0.29
LUSC	chr8	60853395	Missense_Mutation	rs758745100	G2224S	0.33
LUSC	chr8	60841749	Frame_Shift_Del	novel	*R1548Gfs11**	0.23
LUSC	chr8	60856718	Missense_Mutation	novel	T2480S	0.32
LUSC	chr8	60852109	Missense_Mutation	novel	A1919V	0.23
LUSC	chr8	60836935	Missense_Mutation	novel	G1370R	0.24
LUSC	chr8	60781296	Missense_Mutation	NA	K654N	0.28
LUSC	chr8	60865389	Missense_Mutation	NA	N2817I	0.17
LUSC	chr8	60853437	Nonsense_Mutation	NA	E2238*	0.57
LUSC	chr8	60836927	Missense_Mutation	novel	R1367M	0.17
LUSC	chr8	60856525	Silent	novel	A2415A	0.14
LUSC	chr8	60823901	Missense_Mutation	novel	L1088W	0.26
LUSC	chr8	60844954	Silent	NA	L1647L	0.23
LUSC	chr8	60795027	Missense_Mutation	NA	K713T	0.35
LUSC	chr8	60742879	Missense_Mutation	novel	V483F	0.38
LUSC	chr8	60853126	Missense_Mutation	rs753361097	N2134S	0.09
LUSC	chr8	60865327	Silent	novel	L2796L	0.45
LUSC	chr8	60742842	Frame_Shift_Ins	novel	*L471Ffs104**	0.37
LUSC	chr8	60828663	Missense_Mutation	NA	E1127K	0.33
LUSC	chr8	60822687	Missense_Mutation	NA	G1048W	0.35
LUSC	chr8	60862261	Silent	NA	N2632N	0.2
LUSC	chr8	60841731	Missense_Mutation	novel	D1541Y	0.23
LUSC	chr8	60741886	Missense_Mutation	novel	V152L	0.12
LUSC	chr8	60741740	Missense_Mutation	NA	S103L	0.39
LUSC	chr8	60823940	Missense_Mutation	novel	C1101F	0.2
LUSC	chr8	60742799	Missense_Mutation	novel	Q456L	0.21
LUSC	chr8	60838243	Silent	NA	S1507S	0.24
LUSC	chr8	60742646	Missense_Mutation	NA	P405L	0.1
LUSC	chr8	60841980	Missense_Mutation	NA	R1593L	0.29
LUSC	chr8	60852218	Missense_Mutation	novel	R1955S	0.23
LUSC	chr8	60865523	Missense_Mutation	novel	D2862H	0.11
LUSC	chr8	60841977	Missense_Mutation	novel	R1592L	0.4
LUSC	chr8	60862311	Missense_Mutation	novel	V2649D	0.28
LUSC	chr8	60848526	Missense_Mutation	novel	R1741H	0.29
LUSC	chr8	60854391	Missense_Mutation	NA	F2268L	0.28
LUSC	chr8	60865363	Silent	rs773594482	N2808N	0.25
LUSC	chr8	60795022	Silent	NA	K711K	0.09
LUSC	chr8	60816468	Frame_Shift_Del	novel	*A861Qfs27**	0.18
LUSC	chr8	60852671	Missense_Mutation	rs764358718	R2023M	0.26
LUSC	chr8	60822564	Missense_Mutation	NA	L1007F	0.24
LUSC	chr8	60836931	Silent	NA	A1368A	0.27
LUSC	chr8	60852847	Missense_Mutation	novel	S2041Y	0.15
LUSC	chr8	60742495	Missense_Mutation	NA	S355P	0.28
LUSC	chr8	60854454	Missense_Mutation	novel	M2289I	0.15
LUSC	chr8	60823899	Silent	NA	I1087I	0.33
LUSC	chr8	60830497	Missense_Mutation	novel	G1233V	0.22
LUSC	chr8	60841682	Silent	novel	S1524S	0.24
LUSC	chr8	60741467	Missense_Mutation	novel	E12V	0.5
LUSC	chr8	60845293	Silent	novel	V1698V	0.11
OV	chr8	60865289	Missense_Mutation	novel	T2784S	0.24
OV	chr8	60742217	Nonsense_Mutation	novel	*A263Rfs5**	0.03
OV	chr8	60801577	Missense_Mutation	NA	R809H	0.38
OV	chr8	60742018	Missense_Mutation	novel	G196R	0.07
OV	chr8	60741837	Silent	NA	G135G	0.22
OV	chr8	60836969	Missense_Mutation	NA	C1381F	0.24
OV	chr8	60844949	Missense_Mutation	novel	I1646F	0.04
OV	chr8	60865513	Frame_Shift_Ins	novel	*S2860Kfs9**	0.3
OV	chr8	60741686	Missense_Mutation	novel	Q85L	0.05
OV	chr8	60830486	Silent	NA	L1229L	0.15
OV	chr8	60853061	Silent	novel	T2112T	0.04
OV	chr8	60853131	Missense_Mutation	novel	G2136R	0.08
OV	chr8	60823875	Silent	NA	A1079A	0.3
OV	chr8	60865625	Missense_Mutation	NA	S2896P	0.24
OV	chr8	60828682	Missense_Mutation	NA	T1133M	0.44
OV	chr8	60852691	Missense_Mutation	rs143796440	V2030I	0.41
OV	chr8	60856676	Missense_Mutation	novel	I2466F	0.1
OV	chr8	60838096	Silent	NA	K1458K	0.41
OV	chr8	60741632	Missense_Mutation	novel	T67K	0.07
OV	chr8	60838115	Nonsense_Mutation	NA	R1465*	0.59
OV	chr8	60742973	Missense_Mutation	rs748754045	C514S	0.1
OV	chr8	60742115	Missense_Mutation	novel	A228V	0.05
OV	chr8	60845031	In_Frame_Ins	novel	D1673_G1674insLF	0.02
OV	chr8	60853204	Nonsense_Mutation	novel	*H2161Efs4**	0.12
OV	chr8	60837754	Missense_Mutation	novel	M1424I	0.36
OV	chr8	60852538	Missense_Mutation	novel	S1979P	0.26
PAAD	chr8	60850552	Missense_Mutation	novel	G1822S	0.05
PAAD	chr8	60854431	Frame_Shift_Ins	novel	*T2283Nfs20**	0.05
PAAD	chr8	60816501	Splice_Region	novel	E871E	0.15
PAAD	chr8	60822078	Missense_Mutation	novel	N964H	0.09
PAAD	chr8	60836225	Missense_Mutation	novel	I1311V	0.17
PAAD	chr8	60837765	Missense_Mutation	novel	A1428D	0.16
PAAD	chr8	60856152	Missense_Mutation	novel	A2372S	0.27
PRAD	chr8	60781143	Frame_Shift_Ins	novel	*N604Kfs10**	0.5	ResIII
PRAD	chr8	60741769	Missense_Mutation	NA	V113L	0.16
PRAD	chr8	60821911	Missense_Mutation	rs753887911	P940L	0.27
PRAD	chr8	60865336	Missense_Mutation	NA	M2799I	0.21
PRAD	chr8	60743035	Nonsense_Mutation	novel	Q535*	0.27
READ	chr8	60865027	Silent	NA	P2696P	0.63
READ	chr8	60856784	Missense_Mutation	NA	L2502V	0.39
READ	chr8	60865206	Missense_Mutation	novel	T2756R	0.19
READ	chr8	60865456	Missense_Mutation	novel	S2839R	0.1
READ	chr8	60823892	Missense_Mutation	NA	E1085G	0.41
READ	chr8	60781125	Missense_Mutation	NA	K597N	0.37	ResIII
READ	chr8	60781216	Nonsense_Mutation	NA	E628*	0.45	ResIII
READ	chr8	60822596	Silent	NA	G1017G	0.35
READ	chr8	60865533	Missense_Mutation	rs147534616	S2865L	0.23
SARC	chr8	60830519	Missense_Mutation	novel	N1240K	0.13
SARC	chr8	60856828	Silent	novel	R2516R	0.22
SARC	chr8	60852831	Missense_Mutation	novel	P2036S	0.28
SARC	chr8	60866393	3'UTR	novel		0.29
SARC	chr8	60856709	Missense_Mutation	rs762534670	A2477S	0.06
SARC	chr8	60742702	Missense_Mutation	novel	V424F	0.4
SARC	chr8	60850582	Nonsense_Mutation	novel	E1832*	0.34
SARC	chr8	60742252	Missense_Mutation	novel	R274G	0.11
SKCM	chr8	60844891	Silent	novel	S1626S	0.27
SKCM	chr8	60853094	Silent	novel	S2123S	0.13
SKCM	chr8	60741530	Missense_Mutation	novel	P33L	0.48
SKCM	chr8	60836272	Silent	NA	L1326L	0.38
SKCM	chr8	60742923	Silent	novel	P497P	0.38
SKCM	chr8	60781196	Missense_Mutation	novel	P621L	0.3	ResIII
SKCM	chr8	60830439	Nonsense_Mutation	NA	Q1214*	0.26
SKCM	chr8	60849048	Splice_Region	rs769450172		0.09
SKCM	chr8	60856749	Missense_Mutation	rs371595770	S2490L	0.18
SKCM	chr8	60865394	Missense_Mutation	NA	P2819S	0.15
SKCM	chr8	60865847	Missense_Mutation	NA	L2970F	0.35
SKCM	chr8	60830454	Nonsense_Mutation	NA	R1219*	0.07
SKCM	chr8	60820050	Missense_Mutation	NA	R886Q	0.3
SKCM	chr8	60836892	Silent	NA	P1355P	0.25
SKCM	chr8	60741729	Silent	NA	A99A	0.73
SKCM	chr8	60837816	Missense_Mutation	NA	R1445T	0.19
SKCM	chr8	60844868	Missense_Mutation	rs746823883	G1619R	0.36
SKCM	chr8	60844869	Missense_Mutation	novel	G1619E	0.38
SKCM	chr8	60856771	Silent	novel	L2497L	0.31
SKCM	chr8	60856772	Missense_Mutation	novel	L2498F	0.32
SKCM	chr8	60742645	Missense_Mutation	novel	P405S	0.26
SKCM	chr8	60856721	Nonsense_Mutation	novel	Q2481*	0.48
SKCM	chr8	60781096	Missense_Mutation	NA	P588S	0.23
SKCM	chr8	60865656	Missense_Mutation	NA	S2906F	0.26
SKCM	chr8	60852152	Silent	novel	A1933A	0.41
SKCM	chr8	60852154	Frame_Shift_Del	novel	*L1934Qfs2**	0.41
SKCM	chr8	60853093	Missense_Mutation	NA	S2123F	0.5
SKCM	chr8	60845002	Silent	NA	F1663F	0.08
SKCM	chr8	60852548	Missense_Mutation	NA	G1982E	0.31
SKCM	chr8	60822741	Missense_Mutation	NA	P1066S	0.39
SKCM	chr8	60853248	Missense_Mutation	novel	V2175M	0.13
SKCM	chr8	60856782	Missense_Mutation	NA	S2501F	0.42
SKCM	chr8	60844892	Missense_Mutation	rs769675553	H1627Y	0.27
SKCM	chr8	60865210	Silent	novel	S2757S	0.25
SKCM	chr8	60865211	Missense_Mutation	novel	L2758F	0.25
SKCM	chr8	60836192	Missense_Mutation	NA	P1300S	0.34
SKCM	chr8	60800494	Missense_Mutation	NA	S782F	0.18
SKCM	chr8	60854373	Silent	NA	V2262V	0.37
SKCM	chr8	60836897	Missense_Mutation	NA	S1357F	0.09
SKCM	chr8	60852073	Missense_Mutation	novel	S1907L	0.36
SKCM	chr8	60828738	Missense_Mutation	NA	E1152K	0.71
SKCM	chr8	60856771	Silent	novel	L2497L	0.53
SKCM	chr8	60822598	Missense_Mutation	novel	P1018L	0.09
SKCM	chr8	60800436	Silent	novel	L763L	0.48
SKCM	chr8	60822723	Missense_Mutation	NA	E1060K	0.34
SKCM	chr8	60854510	Missense_Mutation	rs768152792	S2308L	0.31
SKCM	chr8	60853435	Missense_Mutation	NA	S2237F	0.19
SKCM	chr8	60823906	Missense_Mutation	novel	D1090N	0.28
SKCM	chr8	60856004	Silent	NA	N2322N	0.13
SKCM	chr8	60742492	Missense_Mutation	NA	P354S	0.6
SKCM	chr8	60742975	Missense_Mutation	NA	P515S	0.27
SKCM	chr8	60742235	Missense_Mutation	NA	S268F	0.43
SKCM	chr8	60854510	Missense_Mutation	rs768152792	S2308L	0.97
SKCM	chr8	60742267	Missense_Mutation	novel	P279S	0.47
SKCM	chr8	60741722	Missense_Mutation	novel	G97E	0.5
SKCM	chr8	60853495	Missense_Mutation	NA	P2257L	0.3
STAD	chr8	60853390	Missense_Mutation	NA	E2222G	0.25
STAD	chr8	60852833	Silent	rs372755547	P2036P	0.14
STAD	chr8	60823984	Missense_Mutation	NA	K1116E	0.15
STAD	chr8	60852169	Missense_Mutation	NA	R1939Q	0.22
STAD	chr8	60822598	Frame_Shift_Ins	novel	*L1020Ffs33**	0.14
STAD	chr8	60822027	Nonsense_Mutation	rs200220845	R947*	0.17
STAD	chr8	60856752	Missense_Mutation	rs528722099	R2491H	0.27
STAD	chr8	60844908	Missense_Mutation	rs775776506	R1632H	0.43
STAD	chr8	60741792	Silent	rs375438732	G120G	0.1
STAD	chr8	60742829	Missense_Mutation	rs71640285	S466L	0.16
STAD	chr8	60742292	Missense_Mutation	NA	P287L	0.15
STAD	chr8	60800442	Missense_Mutation	novel	F765L	0.27
STAD	chr8	60850527	Silent	rs373869399	P1813P	0.15
STAD	chr8	60861054	Frame_Shift_Del	novel	*N2588Ifs4**	0.15
STAD	chr8	60865498	Silent	NA	E2853E	0.32
STAD	chr8	60845252	Splice_Region	NA	L1685L	0.28
STAD	chr8	60856816	Silent	NA	R2512R	0.07
STAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.44
STAD	chr8	60865465	Silent	novel	K2842K	0.34
STAD	chr8	60865808	Missense_Mutation	rs762553908	D2957N	0.37
STAD	chr8	60830510	Silent	rs372498366	N1237N	0.51
STAD	chr8	60836160	Missense_Mutation	NA	A1289V	0.36
STAD	chr8	60836957	Missense_Mutation	NA	A1377V	0.44
STAD	chr8	60865029	Missense_Mutation	NA	E2697G	0.54
STAD	chr8	60781080	Silent	NA	K582K	0.33
STAD	chr8	60856533	Missense_Mutation	rs761410781	R2418Q	0.31
STAD	chr8	60742291	Missense_Mutation	novel	P287S	0.06
STAD	chr8	60824079	Intron	rs748147602		0.27
STAD	chr8	60830358	Silent	novel	L1187L	0.31
STAD	chr8	60830555	Silent	NA	C1252C	0.18
STAD	chr8	60852094	Missense_Mutation	NA	R1914H	0.14
STAD	chr8	60865292	Missense_Mutation	NA	A2785T	0.24
STAD	chr8	60856484	Silent	NA	R2402R	0.17
STAD	chr8	60742507	Missense_Mutation	NA	Q359E	0.27
STAD	chr8	60741937	Missense_Mutation	novel	P169S	0.18
STAD	chr8	60741798	Silent	novel	Q122Q	0.29
STAD	chr8	60742211	Missense_Mutation	NA	P260L	0.15
STAD	chr8	60852169	Missense_Mutation	NA	R1939Q	0.15
STAD	chr8	60841755	Splice_Site	NA	X1548_splice	0.26
STAD	chr8	60852119	Silent	NA	R1922R	0.23
STAD	chr8	60742599	Silent	NA	T389T	0.21
STAD	chr8	60742528	Missense_Mutation	NA	P366S	0.06
STAD	chr8	60741689	Missense_Mutation	NA	P86L	0.41
STAD	chr8	60865152	Missense_Mutation	rs761409446	T2738M	0.36
STAD	chr8	60781015	Missense_Mutation	novel	P561T	0.18
STAD	chr8	60742783	Missense_Mutation	NA	G451S	0.18
STAD	chr8	60853318	Missense_Mutation	novel	G2198V	0.3
STAD	chr8	60836157	Frame_Shift_Ins	novel	*A1289Cfs8**	0.24
STAD	chr8	60836158	Frame_Shift_Ins	novel	*A1289Wfs5**	0.24
STAD	chr8	60741957	Frame_Shift_Del	novel	*P178Lfs33**	0.19
STAD	chr8	60853110	Frame_Shift_Del	novel	*N2130Tfs14**	0.25
STAD	chr8	60742180	Missense_Mutation	rs368934543	R250C	0.08
STAD	chr8	60852883	Missense_Mutation	NA	R2053Q	0.14
STAD	chr8	60824075	Intron	novel		0.18
STAD	chr8	60741521	Missense_Mutation	rs768014298	P30L	0.17
STAD	chr8	60852937	Missense_Mutation	NA	H2071R	0.33
STAD	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.27
STAD	chr8	60845047	Silent	NA	A1678A	0.17
STAD	chr8	60781021	Missense_Mutation	NA	L563V	0.15
STAD	chr8	60856502	Missense_Mutation	NA	E2408K	0.1
STAD	chr8	60741677	Missense_Mutation	novel	L82P	0.29
STAD	chr8	60865690	Silent	rs761033941	T2917T	0.21
STAD	chr8	60830478	Missense_Mutation	NA	T1227A	0.13
STAD	chr8	60741516	Silent	NA	G28G	0.15
STAD	chr8	60852833	Silent	rs372755547	P2036P	0.25
STAD	chr8	60853355	Missense_Mutation	NA	E2210D	0.12
STAD	chr8	60861097	Missense_Mutation	novel	Y2601C	0.26
THCA	chr8	60822566	Silent	novel	L1007L	0.13
THCA	chr8	60861092	In_Frame_Ins	novel	P2599_T2600insAE	0.09
UCEC	chr8	60856183	Missense_Mutation	rs189926848	T2382M	0.43
UCEC	chr8	60865728	Missense_Mutation	NA	A2930V	0.38
UCEC	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.36
UCEC	chr8	60741690	Silent	rs750046226	P86P	0.29
UCEC	chr8	60828759	Nonsense_Mutation	NA	E1159*	0.18
UCEC	chr8	60861015	Missense_Mutation	rs375629413	L2574I	0.37
UCEC	chr8	60741690	Silent	rs750046226	P86P	0.19
UCEC	chr8	60742367	Missense_Mutation	NA	R312Q	0.3
UCEC	chr8	60855994	Missense_Mutation	rs765943226	R2319H	0.09
UCEC	chr8	60821802	Missense_Mutation	novel	Y904H	0.07
UCEC	chr8	60851309	Missense_Mutation	novel	I1885M	0.31
UCEC	chr8	60822688	Missense_Mutation	novel	G1048V	0.36
UCEC	chr8	60823898	Missense_Mutation	novel	I1087S	0.49
UCEC	chr8	60824108	Intron	novel		0.41
UCEC	chr8	60865460	Missense_Mutation	novel	S2841P	0.29
UCEC	chr8	60866470	3'UTR	novel		0.43
UCEC	chr8	60822599	Frame_Shift_Del	NA	L1020*	0.18
UCEC	chr8	60852893	Silent	rs768797787	Y2056Y	0.23
UCEC	chr8	60866287	3'UTR	novel		0.31
UCEC	chr8	60795129	Splice_Site	novel	X746_splice	0.14
UCEC	chr8	60845405	Missense_Mutation	novel	N1736D	0.1
UCEC	chr8	60742593	Missense_Mutation	novel	Q387H	0.37
UCEC	chr8	60850516	Nonsense_Mutation	NA	R1810*	0.42
UCEC	chr8	60856677	Missense_Mutation	novel	I2466T	0.08
UCEC	chr8	60866848	3'UTR	novel		0.4
UCEC	chr8	60742750	Missense_Mutation	novel	P440T	0.38
UCEC	chr8	60822047	Missense_Mutation	novel	W953C	0.4
UCEC	chr8	60830364	Missense_Mutation	novel	R1189C	0.4
UCEC	chr8	60852059	Nonsense_Mutation	novel	Y1902*	0.43
UCEC	chr8	60852529	Missense_Mutation	NA	R1976C	0.29
UCEC	chr8	60856875	Missense_Mutation	rs201032343	T2532M	0.28
UCEC	chr8	60741707	Missense_Mutation	novel	N92S	0.84
UCEC	chr8	60866097	3'UTR	novel		0.62
UCEC	chr8	60866510	3'UTR	novel		0.56
UCEC	chr8	60845062	Splice_Region	rs529369619	S1683S	0.18
UCEC	chr8	60854448	Missense_Mutation	novel	F2287L	0.29
UCEC	chr8	60866022	3'UTR	novel		0.24
UCEC	chr8	60837757	Silent	rs368919638	F1425F	0.37
UCEC	chr8	60852697	Missense_Mutation	novel	P2032S	0.06
UCEC	chr8	60856546	Silent	NA	E2422E	0.44
UCEC	chr8	60741724	Missense_Mutation	NA	L98I	0.36
UCEC	chr8	60852529	Missense_Mutation	NA	R1976C	0.19
UCEC	chr8	60861033	Silent	NA	L2580L	0.16
UCEC	chr8	60865184	Missense_Mutation	NA	L2749M	0.22
UCEC	chr8	60853355	Frame_Shift_Ins	novel	*A2211Ffs6**	0.11
UCEC	chr8	60781229	Nonsense_Mutation	novel	S633*	0.05	ResIII
UCEC	chr8	60781230	Missense_Mutation	novel	N632K	0.03	ResIII
UCEC	chr8	60851286	Missense_Mutation	NA	D1878N	0.38
UCEC	chr8	60853355	Frame_Shift_Ins	novel	*A2211Ffs9**	0.15
UCEC	chr8	60742954	Missense_Mutation	novel	F508V	0.04
UCEC	chr8	60845313	Missense_Mutation	rs373986410	P1705L	0.24
UCEC	chr8	60852094	Missense_Mutation	NA	R1914H	0.21
UCEC	chr8	60856499	Missense_Mutation	novel	I2407V	0.06
UCEC	chr8	60856501	Frame_Shift_Ins	novel	*E2408Tfs4**	0.07
UCEC	chr8	60830508	Missense_Mutation	NA	N1237D	0.26
UCEC	chr8	60741645	Silent	novel	H71H	0.17
UCEC	chr8	60865078	Silent	novel	G2713G	0.29
UCEC	chr8	60865495	Silent	rs794727604	D2852D	0.16
UCEC	chr8	60865534	Silent	rs757002335	S2865S	0.36
UCEC	chr8	60741832	Missense_Mutation	NA	H134Y	0.38
UCEC	chr8	60741948	Silent	rs377332156	P172P	0.57
UCEC	chr8	60742235	Missense_Mutation	NA	S268F	0.38
UCEC	chr8	60820051	Silent	novel	R886R	0.06
UCEC	chr8	60841713	Missense_Mutation	NA	A1535T	0.2
UCEC	chr8	60844987	Silent	NA	E1658E	0.2
UCEC	chr8	60850527	Silent	rs373869399	P1813P	0.16
UCEC	chr8	60856473	Missense_Mutation	rs758378293	R2398H	0.16
UCEC	chr8	60860967	Missense_Mutation	NA	P2558S	0.42
UCEC	chr8	60865555	Silent	NA	G2872G	0.2
UCEC	chr8	60852093	Missense_Mutation	rs373823856	R1914C	0.1
UCEC	chr8	60816460	Nonsense_Mutation	NA	R858*	0.23
UCEC	chr8	60742587	Silent	NA	Q385Q	0.38
UCEC	chr8	60851101	Missense_Mutation	NA	I1868M	0.27
UCEC	chr8	60862653	Splice_Site	novel	X2692_splice	0.21
UCEC	chr8	60845394	Missense_Mutation	novel	K1732T	0.4
UCEC	chr8	60741320	5'UTR	novel		0.35
UCEC	chr8	60742263	Silent	rs775415630	P277P	0.88
UCEC	chr8	60816433	Missense_Mutation	rs775998353	D849Y	0.64
UCEC	chr8	60866766	3'UTR	novel		0.2
UCEC	chr8	60742282	Missense_Mutation	novel	A284T	0.34
UCEC	chr8	60742567	Nonsense_Mutation	novel	Q379*	0.22
UCEC	chr8	60800428	Missense_Mutation	novel	T760I	0.3
UCEC	chr8	60853444	Missense_Mutation	novel	D2240G	0.2
UCEC	chr8	60856047	Missense_Mutation	rs765610436	R2337C	0.35
UCEC	chr8	60856816	Silent	NA	R2512R	0.36
UCEC	chr8	60823972	Missense_Mutation	novel	N1112D	0.22
UCEC	chr8	60865919	Missense_Mutation	novel	E2994K	0.21
UCEC	chr8	60848512	Splice_Region	NA		0.27
UCEC	chr8	60742625	Missense_Mutation	novel	P398L	0.47
UCEC	chr8	60801576	Missense_Mutation	novel	R809C	0.41
UCEC	chr8	60841868	Missense_Mutation	novel	P1556S	0.4
UCEC	chr8	60853313	Silent	rs746103884	T2196T	0.35
UCEC	chr8	60865101	Missense_Mutation	novel	P2721L	0.41
UCEC	chr8	60865471	Missense_Mutation	NA	E2844D	0.27
UCEC	chr8	60865894	Frame_Shift_Ins	rs771806027	*D2988Gfs2**	0.3
UCEC	chr8	60852078	Missense_Mutation	novel	L1909M	0.46
UCEC	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.21
UCEC	chr8	60865680	Missense_Mutation	novel	G2914V	0.31
UCEC	chr8	60742716	Silent	novel	P428P	0.28
UCEC	chr8	60741518	Missense_Mutation	novel	Y29C	0.33
UCEC	chr8	60816410	Missense_Mutation	novel	A841V	0.35
UCEC	chr8	60828748	Missense_Mutation	rs762669262	R1155H	0.49
UCEC	chr8	60836282	Missense_Mutation	rs369542138	R1330W	0.45
UCEC	chr8	60852087	Missense_Mutation	novel	R1912C	0.5
UCEC	chr8	60865098	Missense_Mutation	novel	R2720M	0.31
UCEC	chr8	60742200	Silent	rs727503859	F256F	0.59
UCEC	chr8	60816413	Missense_Mutation	novel	S842Y	0.6
UCEC	chr8	60850620	Splice_Region	rs368279646	D1844D	0.32
UCEC	chr8	60821897	Silent	novel	L935L	0.46
UCEC	chr8	60850540	Missense_Mutation	novel	L1818V	0.37
UCEC	chr8	60742659	Silent	novel	P409P	0.12
UCEC	chr8	60800478	Missense_Mutation	NA	A777T	0.26
UCEC	chr8	60808252	Missense_Mutation	NA	F826L	0.44
UCEC	chr8	60856650	Missense_Mutation	novel	N2457I	0.36
UCEC	chr8	60836932	Nonsense_Mutation	novel	G1369*	0.21
UCEC	chr8	60856533	Missense_Mutation	rs761410781	R2418Q	0.04
UCEC	chr8	60741690	Silent	rs750046226	P86P	0.36
UCEC	chr8	60742236	Silent	rs780756877	S268S	0.32
UCEC	chr8	60816463	Missense_Mutation	novel	F859L	0.2
UCEC	chr8	60741477	Silent	novel	N15N	0.35
UCEC	chr8	60850582	Missense_Mutation	rs763196772	E1832K	0.47
UCEC	chr8	60865295	Missense_Mutation	rs765315726	G2786R	0.39
UCEC	chr8	60865579	Silent	rs374937585	P2880P	0.24
UCEC	chr8	60853394	Silent	rs556577614	V2223V	0.13
UCEC	chr8	60822525	Missense_Mutation	novel	E994K	0.21
UCEC	chr8	60838199	Missense_Mutation	novel	R1493C	0.39
UCEC	chr8	60851036	Missense_Mutation	novel	E1847K	0.43
UCEC	chr8	60861084	Missense_Mutation	novel	L2597M	0.23
UCEC	chr8	60866442	3'UTR	novel		0.35
UCEC	chr8	60820050	Missense_Mutation	NA	R886Q	0.36
UCEC	chr8	60821922	Missense_Mutation	rs587783435	R944C	0.38
UCEC	chr8	60741570	Silent	novel	G46G	0.28
UCEC	chr8	60781363	Missense_Mutation	novel	P677S	0.07
UCEC	chr8	60837757	Silent	rs368919638	F1425F	0.3
UCEC	chr8	60742523	Missense_Mutation	novel	Q364L	0.46
UCEC	chr8	60822572	Missense_Mutation	novel	E1009D	0.51
UCEC	chr8	60823854	Missense_Mutation	novel	K1072N	0.38
UCEC	chr8	60836932	Nonsense_Mutation	novel	G1369*	0.37
UCEC	chr8	60853296	Nonsense_Mutation	novel	E2191*	0.22
UCEC	chr8	60853436	Silent	rs370385319	S2237S	0.2
UCEC	chr8	60844898	Missense_Mutation	rs745837768	R1629C	0.51
UCEC	chr8	60865152	Missense_Mutation	rs761409446	T2738M	0.52
UCEC	chr8	60741690	Silent	rs750046226	P86P	0.19
UCEC	chr8	60741942	Silent	rs748841915	P170P	0.16
UCEC	chr8	60742313	Missense_Mutation	novel	S294Y	0.56
UCEC	chr8	60856674	Missense_Mutation	novel	F2465C	0.06
UCEC	chr8	60862560	Missense_Mutation	novel	M2662V	0.45
UCEC	chr8	60866570	3'UTR	novel		0.54
UCEC	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.43
UCEC	chr8	60853436	Silent	rs370385319	S2237S	0.37
UCEC	chr8	60742231	Missense_Mutation	novel	E267K	0.08
UCEC	chr8	60816440	Missense_Mutation	NA	R851I	0.2
UCEC	chr8	60866722	3'UTR	novel		0.2
UCEC	chr8	60808238	Nonsense_Mutation	novel	E822*	0.35
UCEC	chr8	60860998	Missense_Mutation	rs369807016	R2568Q	0.21
UCEC	chr8	60853135	Missense_Mutation	NA	A2137V	0.08
UCEC	chr8	60861031	Missense_Mutation	novel	R2579M	0.3
UCEC	chr8	60856034	Nonsense_Mutation	NA	W2332*	0.4
UCEC	chr8	60865895	Frame_Shift_Del	NA	*D2988Mfs3**	0.21
UCEC	chr8	60830365	Missense_Mutation	NA	R1189H	0.09
UCEC	chr8	60856171	Missense_Mutation	novel	E2378V	0.1
UCEC	chr8	60741446	Missense_Mutation	novel	G5E	0.58
UCEC	chr8	60865240	Silent	novel	L2767L	0.6
UCEC	chr8	60853076	Frame_Shift_Ins	novel	*N2118Qfs35**	0.04
UCEC	chr8	60741654	Silent	novel	Q74Q	0.29
UCEC	chr8	60848580	Missense_Mutation	novel	K1759R	0.32
UCEC	chr8	60851285	Missense_Mutation	novel	E1877D	0.38
UCEC	chr8	60856805	Missense_Mutation	NA	M2509V	0.18
UCEC	chr8	60865873	Silent	novel	G2978G	0.17
UCEC	chr8	60781260	Frame_Shift_Ins	novel	*K645Efs31**	0.39
UCEC	chr8	60816433	Missense_Mutation	rs775998353	D849Y	0.39
UCEC	chr8	60828682	Missense_Mutation	NA	T1133M	0.53
UCEC	chr8	60742829	Missense_Mutation	rs71640285	S466L	0.58
UCEC	chr8	60856051	Missense_Mutation	NA	Q2338P	0.48
UCEC	chr8	60741508	Nonsense_Mutation	NA	E26*	0.3
UCEC	chr8	60830387	Missense_Mutation	NA	K1196N	0.29
UCEC	chr8	60845402	Missense_Mutation	novel	C1735R	0.08
UCEC	chr8	60852641	Missense_Mutation	NA	K2013T	0.24
UCEC	chr8	60865114	Silent	rs778052548	I2725I	0.29
UCEC	chr8	60856724	Missense_Mutation	rs369402366	M2482V	0.33
UCEC	chr8	60742971	Silent	novel	T513T	0.42
UCEC	chr8	60781162	Missense_Mutation	novel	D610Y	0.17	ResIII
UCEC	chr8	60795022	Frame_Shift_Ins	novel	*V714Gfs10**	0.18
UCEC	chr8	60800479	Missense_Mutation	novel	A777V	0.34
UCEC	chr8	60820067	Missense_Mutation	rs768961973	R892C	0.13
UCEC	chr8	60820068	Missense_Mutation	rs200188105	R892H	0.22
UCEC	chr8	60822115	Missense_Mutation	novel	V976A	0.23
UCEC	chr8	60822703	Missense_Mutation	novel	R1053H	0.19
UCEC	chr8	60828749	Silent	novel	R1155R	0.14
UCEC	chr8	60841676	Silent	novel	D1522D	0.3
UCEC	chr8	60841880	Missense_Mutation	novel	K1560Q	0.38
UCEC	chr8	60842039	Missense_Mutation	novel	L1613M	0.2
UCEC	chr8	60848546	Missense_Mutation	novel	L1748I	0.25
UCEC	chr8	60854518	Missense_Mutation	rs769906291	P2311S	0.2
UCEC	chr8	60856769	Missense_Mutation	rs771698896	L2497F	0.18
UCEC	chr8	60860962	Missense_Mutation	novel	N2556S	0.16
UCEC	chr8	60865357	Silent	novel	L2806L	0.28
UCEC	chr8	60865507	Missense_Mutation	novel	D2856E	0.19
UCEC	chr8	60856751	Missense_Mutation	rs755492299	R2491C	0.29
UCEC	chr8	60837750	Missense_Mutation	NA	E1423G	0.39
UCEC	chr8	60850516	Nonsense_Mutation	NA	R1810*	0.32
UCEC	chr8	60856183	Missense_Mutation	rs189926848	T2382M	0.36
UCEC	chr8	60865566	Missense_Mutation	NA	A2876D	0.35
UCEC	chr8	60861062	Missense_Mutation	novel	K2589N	0.4
UCEC	chr8	60781420	Frame_Shift_Del	novel	*K697Sfs14**	0.35
UCEC	chr8	60822590	Silent	novel	I1015I	0.36
UCEC	chr8	60830520	Silent	novel	L1241L	0.37
UCEC	chr8	60836918	Missense_Mutation	novel	L1364P	0.4
UCEC	chr8	60866099	3'UTR	novel		0.48
UCEC	chr8	60866480	3'UTR	novel		0.46
UCEC	chr8	60816413	Missense_Mutation	novel	S842F	0.35
UCEC	chr8	60821851	Missense_Mutation	novel	R920Q	0.31
UCEC	chr8	60822055	Missense_Mutation	rs367557471	S956L	0.3
UCEC	chr8	60851319	Missense_Mutation	novel	G1889C	0.42
UCEC	chr8	60853366	Missense_Mutation	novel	V2214A	0.27
UCEC	chr8	60822503	Frame_Shift_Del	novel	*R987Hfs5**	0.12
UCS	chr8	60862323	Missense_Mutation	rs747082615	R2653Q	0.2
UCS	chr8	60865894	Frame_Shift_Ins	rs771806027	*D2988Gfs2**	0.68

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.1458	0.021977
READ	DEL	0.0424	0.20625
SARC	AMP	0.2646	0.18425
THCA	DEL	0.008	0.038162

Survival Analysis

Cancer	P-value	Q-value
THYM	0.035	Kaplan-Meier Survival Analysis
SARC	0.0068	Kaplan-Meier Survival Analysis
MESO	0.0011	Kaplan-Meier Survival Analysis
SKCM	0.0035	Kaplan-Meier Survival Analysis
CESC	0.0044	Kaplan-Meier Survival Analysis
READ	0.046	Kaplan-Meier Survival Analysis
LAML	0.047	Kaplan-Meier Survival Analysis
UCEC	0.00013	Kaplan-Meier Survival Analysis
LIHC	0.00015	Kaplan-Meier Survival Analysis
LGG	0.00076	Kaplan-Meier Survival Analysis
CHOL	0.016	Kaplan-Meier Survival Analysis
UVM	0.00045	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742