EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171453 (Gene tree)
Gene ID: 9533
Gene Symbol: POLR1C
Alias: RPA40|RPA39|RPA5|RPAC1
Full Name: RNA polymerase I and III subunit C
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 52,718 bases
Position: chr6:43,509,702-43,562,419
Accession: 20194
RBP type: canonical RBP
Summary: The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000496001	RNA_pol_A_bac	PF01000.26	4.3e-30	1	1
ENSP00000496018	RNA_pol_A_bac	PF01000.26	5.1e-30	1	1
ENSP00000307212	RNA_pol_A_bac	PF01000.26	6e-30	1	1
ENSP00000496683	RNA_pol_A_bac	PF01000.26	6e-30	1	1
ENSP00000361465	RNA_pol_A_bac	PF01000.26	6.2e-30	1	1
ENSP00000496044	RNA_pol_A_bac	PF01000.26	6.2e-30	1	1
ENSP00000494368	RNA_pol_A_bac	PF01000.26	6.4e-30	1	1
ENSP00000361419	RNA_pol_A_bac	PF01000.26	4.8e-27	1	1
ENSP00000494529	RNA_pol_A_bac	PF01000.26	4.8e-27	1	1
ENSP00000395401	RNA_pol_A_bac	PF01000.26	7.8e-14	1	1
ENSP00000409536	RNA_pol_A_bac	PF01000.26	3e-07	1	1
ENSP00000496001	RNA_pol_L	PF01193.24	2.2e-22	1	1
ENSP00000361419	RNA_pol_L	PF01193.24	2.7e-22	1	1
ENSP00000494529	RNA_pol_L	PF01193.24	2.7e-22	1	1
ENSP00000361465	RNA_pol_L	PF01193.24	3.9e-22	1	1
ENSP00000496044	RNA_pol_L	PF01193.24	3.9e-22	1	1
ENSP00000494368	RNA_pol_L	PF01193.24	9.8e-11	1	1
ENSP00000496018	RNA_pol_L	PF01193.24	1.5e-10	1	1
ENSP00000307212	RNA_pol_L	PF01193.24	1.6e-10	1	1
ENSP00000496683	RNA_pol_L	PF01193.24	1.6e-10	1	1
ENSP00000395401	RNA_pol_L	PF01193.24	2e-10	1	1
ENSP00000409536	RNA_pol_L	PF01193.24	1.3e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000512472	POLR1C-209	569	-	-	- (aa)	-	-
ENST00000642195	POLR1C-211	1275	-	ENSP00000496044	346 (aa)	-	O15160
ENST00000304004	POLR1C-201	1280	-	ENSP00000307212	342 (aa)	-	O15160
ENST00000646700	POLR1C-217	2444	-	ENSP00000495521	307 (aa)	-	A0A2R8YEZ4
ENST00000643799	POLR1C-213	1085	-	ENSP00000494529	296 (aa)	-	E7EQB9
ENST00000372389	POLR1C-203	1355	-	ENSP00000361465	346 (aa)	-	O15160
ENST00000481352	POLR1C-207	1725	-	-	- (aa)	-	-
ENST00000607635	POLR1C-210	2118	-	ENSP00000496683	342 (aa)	-	O15160
ENST00000428025	POLR1C-205	576	-	ENSP00000395401	124 (aa)	-	D6RDJ3
ENST00000423780	POLR1C-204	418	-	ENSP00000409536	140 (aa)	-	H0Y723
ENST00000372344	POLR1C-202	1119	-	ENSP00000361419	296 (aa)	-	E7EQB9
ENST00000646433	POLR1C-216	1786	-	ENSP00000494368	343 (aa)	-	A0A2R8Y5D3
ENST00000455605	POLR1C-206	1882	-	-	- (aa)	-	-
ENST00000646188	POLR1C-215	1221	-	ENSP00000496001	291 (aa)	-	A0A2R8YEY5
ENST00000488601	POLR1C-208	973	-	-	- (aa)	-	-
ENST00000645141	POLR1C-214	1334	-	ENSP00000496755	151 (aa)	-	A0A2R8Y8D6
ENST00000643341	POLR1C-212	1962	XM_011515000	ENSP00000496018	307 (aa)	XP_011513302	A0A2R8YEZ4

Gene Model

Click here to download ENSG00000171453's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG
hsa04623	Cytosolic DNA-sensing pathway	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000171453	rs201320592	6	43520078	A	GLP-1 levels in response to oral glucose tolerance test (fasting)	29093273	[0.24-0.61] unit increase	0.425	EFO_0008465\|EFO_0004307

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171453's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171453	POLR1C	75	34.409	ENSAPOG00000011708	polr2c	76	30.493	Acanthochromis_polyacanthus
ENSG00000171453	POLR1C	100	74.237	ENSAPOG00000024356	polr1c	100	73.219	Acanthochromis_polyacanthus
ENSG00000171453	POLR1C	75	39.583	ENSAMEG00000017026	POLR2C	67	33.333	Ailuropoda_melanoleuca
ENSG00000171453	POLR1C	100	98.387	ENSAMEG00000012205	POLR1C	99	96.821	Ailuropoda_melanoleuca
ENSG00000171453	POLR1C	100	66.441	ENSACIG00000016268	polr1c	91	63.142	Amphilophus_citrinellus
ENSG00000171453	POLR1C	95	30.714	ENSACIG00000012060	polr2c	87	30.714	Amphilophus_citrinellus
ENSG00000171453	POLR1C	75	34.375	ENSAOCG00000015665	polr2c	76	30.493	Amphiprion_ocellaris
ENSG00000171453	POLR1C	100	72.203	ENSAOCG00000011687	polr1c	97	71.510	Amphiprion_ocellaris
ENSG00000171453	POLR1C	75	34.375	ENSAOCG00000010477	-	76	30.493	Amphiprion_ocellaris
ENSG00000171453	POLR1C	63	33.333	ENSAOCG00000018000	-	72	31.683	Amphiprion_ocellaris
ENSG00000171453	POLR1C	75	34.375	ENSAPEG00000007221	polr2c	76	30.493	Amphiprion_percula
ENSG00000171453	POLR1C	100	72.203	ENSAPEG00000002433	polr1c	100	71.225	Amphiprion_percula
ENSG00000171453	POLR1C	100	74.194	ENSATEG00000005985	polr1c	99	73.926	Anabas_testudineus
ENSG00000171453	POLR1C	95	30.357	ENSATEG00000007143	polr2c	87	30.357	Anabas_testudineus
ENSG00000171453	POLR1C	63	37.037	ENSAPLG00000005385	POLR2C	59	33.333	Anas_platyrhynchos
ENSG00000171453	POLR1C	96	89.076	ENSAPLG00000002908	POLR1C	100	82.333	Anas_platyrhynchos
ENSG00000171453	POLR1C	100	81.759	ENSACAG00000009764	POLR1C	88	81.818	Anolis_carolinensis
ENSG00000171453	POLR1C	75	38.542	ENSACAG00000007514	-	67	32.821	Anolis_carolinensis
ENSG00000171453	POLR1C	100	98.969	ENSANAG00000025805	POLR1C	100	98.649	Aotus_nancymaae
ENSG00000171453	POLR1C	75	39.583	ENSANAG00000005302	POLR2C	67	33.333	Aotus_nancymaae
ENSG00000171453	POLR1C	95	30.000	ENSACLG00000004854	polr2c	87	30.000	Astatotilapia_calliptera
ENSG00000171453	POLR1C	100	75.806	ENSACLG00000006573	polr1c	100	73.064	Astatotilapia_calliptera
ENSG00000171453	POLR1C	75	33.333	ENSAMXG00000012805	polr2c	87	30.714	Astyanax_mexicanus
ENSG00000171453	POLR1C	100	79.839	ENSAMXG00000012062	polr1c	99	72.464	Astyanax_mexicanus
ENSG00000171453	POLR1C	100	97.581	ENSBTAG00000018969	POLR1C	100	97.110	Bos_taurus
ENSG00000171453	POLR1C	75	39.583	ENSBTAG00000001856	POLR2C	67	33.333	Bos_taurus
ENSG00000171453	POLR1C	69	37.079	WBGene00007971	rpb-3	67	30.332	Caenorhabditis_elegans
ENSG00000171453	POLR1C	99	49.834	WBGene00019275	rpac-40	94	46.459	Caenorhabditis_elegans
ENSG00000171453	POLR1C	75	39.583	ENSCJAG00000012016	POLR2C	67	33.333	Callithrix_jacchus
ENSG00000171453	POLR1C	100	98.625	ENSCJAG00000005594	POLR1C	100	98.311	Callithrix_jacchus
ENSG00000171453	POLR1C	75	39.583	ENSCAFG00000008720	POLR2C	67	33.333	Canis_familiaris
ENSG00000171453	POLR1C	100	97.938	ENSCAFG00000001872	POLR1C	100	97.399	Canis_familiaris
ENSG00000171453	POLR1C	100	97.938	ENSCAFG00020012018	POLR1C	100	97.399	Canis_lupus_dingo
ENSG00000171453	POLR1C	75	39.583	ENSCAFG00020007660	POLR2C	67	33.333	Canis_lupus_dingo
ENSG00000171453	POLR1C	100	97.260	ENSCHIG00000004352	POLR1C	100	96.830	Capra_hircus
ENSG00000171453	POLR1C	75	39.583	ENSCHIG00000012072	POLR2C	67	33.333	Capra_hircus
ENSG00000171453	POLR1C	75	39.583	ENSTSYG00000011076	POLR2C	67	33.333	Carlito_syrichta
ENSG00000171453	POLR1C	100	99.194	ENSTSYG00000011921	POLR1C	100	98.986	Carlito_syrichta
ENSG00000171453	POLR1C	100	97.581	ENSCAPG00000015364	POLR1C	88	96.656	Cavia_aperea
ENSG00000171453	POLR1C	75	39.583	ENSCPOG00000004554	POLR2C	67	33.333	Cavia_porcellus
ENSG00000171453	POLR1C	100	97.581	ENSCPOG00000038098	POLR1C	100	97.110	Cavia_porcellus
ENSG00000171453	POLR1C	75	39.583	ENSCCAG00000035768	POLR2C	67	33.333	Cebus_capucinus
ENSG00000171453	POLR1C	100	98.969	ENSCCAG00000020169	POLR1C	100	98.555	Cebus_capucinus
ENSG00000171453	POLR1C	75	39.583	ENSCATG00000040803	POLR2C	67	33.333	Cercocebus_atys
ENSG00000171453	POLR1C	100	99.313	ENSCATG00000044045	POLR1C	100	99.133	Cercocebus_atys
ENSG00000171453	POLR1C	75	39.583	ENSCLAG00000013676	POLR2C	67	33.333	Chinchilla_lanigera
ENSG00000171453	POLR1C	100	96.907	ENSCLAG00000009266	POLR1C	100	96.821	Chinchilla_lanigera
ENSG00000171453	POLR1C	75	39.583	ENSCSAG00000004901	POLR2C	67	33.333	Chlorocebus_sabaeus
ENSG00000171453	POLR1C	100	98.387	ENSCSAG00000011913	POLR1C	100	98.266	Chlorocebus_sabaeus
ENSG00000171453	POLR1C	73	96.226	ENSCHOG00000006601	POLR1C	100	96.226	Choloepus_hoffmanni
ENSG00000171453	POLR1C	71	32.967	ENSCHOG00000002986	POLR2C	64	32.065	Choloepus_hoffmanni
ENSG00000171453	POLR1C	100	87.097	ENSCPBG00000025203	POLR1C	100	85.549	Chrysemys_picta_bellii
ENSG00000171453	POLR1C	63	38.272	ENSCPBG00000022758	POLR2C	62	34.483	Chrysemys_picta_bellii
ENSG00000171453	POLR1C	98	62.810	ENSCING00000003563	-	99	54.493	Ciona_intestinalis
ENSG00000171453	POLR1C	74	32.990	ENSCING00000021895	-	65	31.633	Ciona_intestinalis
ENSG00000171453	POLR1C	71	34.066	ENSCSAVG00000002167	-	66	30.928	Ciona_savignyi
ENSG00000171453	POLR1C	100	100.000	ENSCANG00000043167	POLR1C	100	98.986	Colobus_angolensis_palliatus
ENSG00000171453	POLR1C	75	39.583	ENSCANG00000034876	POLR2C	67	33.333	Colobus_angolensis_palliatus
ENSG00000171453	POLR1C	76	37.113	ENSCGRG00001019477	Polr2c	67	33.846	Cricetulus_griseus_chok1gshd
ENSG00000171453	POLR1C	100	95.376	ENSCGRG00001017533	Polr1c	100	95.376	Cricetulus_griseus_chok1gshd
ENSG00000171453	POLR1C	100	95.189	ENSCGRG00000013225	Polr1c	100	95.318	Cricetulus_griseus_crigri
ENSG00000171453	POLR1C	76	37.113	ENSCGRG00000013273	Polr2c	67	33.846	Cricetulus_griseus_crigri
ENSG00000171453	POLR1C	95	30.357	ENSCSEG00000001719	polr2c	87	30.357	Cynoglossus_semilaevis
ENSG00000171453	POLR1C	100	74.194	ENSCSEG00000018097	polr1c	100	72.046	Cynoglossus_semilaevis
ENSG00000171453	POLR1C	92	69.173	ENSCVAG00000009585	polr1c	88	70.677	Cyprinodon_variegatus
ENSG00000171453	POLR1C	75	34.375	ENSCVAG00000017931	polr2c	74	32.308	Cyprinodon_variegatus
ENSG00000171453	POLR1C	73	69.811	ENSCVAG00000005684	polr1c	88	68.950	Cyprinodon_variegatus
ENSG00000171453	POLR1C	95	30.714	ENSCVAG00000004718	-	87	30.714	Cyprinodon_variegatus
ENSG00000171453	POLR1C	99	76.423	ENSDARG00000039400	polr1c	96	71.470	Danio_rerio
ENSG00000171453	POLR1C	75	35.417	ENSDARG00000033596	polr2c	67	32.308	Danio_rerio
ENSG00000171453	POLR1C	100	98.387	ENSDNOG00000042693	POLR1C	100	96.821	Dasypus_novemcinctus
ENSG00000171453	POLR1C	75	39.583	ENSDNOG00000030752	-	53	34.737	Dasypus_novemcinctus
ENSG00000171453	POLR1C	75	39.583	ENSDORG00000000081	Polr2c	67	33.333	Dipodomys_ordii
ENSG00000171453	POLR1C	100	97.581	ENSDORG00000000429	Polr1c	100	96.243	Dipodomys_ordii
ENSG00000171453	POLR1C	99	58.871	FBgn0031657	CG3756	93	54.140	Drosophila_melanogaster
ENSG00000171453	POLR1C	100	95.161	ENSETEG00000010807	POLR1C	100	91.329	Echinops_telfairi
ENSG00000171453	POLR1C	100	77.419	ENSEBUG00000013725	polr1c	98	73.977	Eptatretus_burgeri
ENSG00000171453	POLR1C	75	39.583	ENSEASG00005005406	POLR2C	67	33.333	Equus_asinus_asinus
ENSG00000171453	POLR1C	100	97.595	ENSEASG00005003338	POLR1C	100	97.110	Equus_asinus_asinus
ENSG00000171453	POLR1C	75	39.583	ENSECAG00000015818	POLR2C	67	33.333	Equus_caballus
ENSG00000171453	POLR1C	100	97.251	ENSECAG00000023516	POLR1C	100	96.959	Equus_caballus
ENSG00000171453	POLR1C	100	97.595	ENSEEUG00000005471	POLR1C	100	97.110	Erinaceus_europaeus
ENSG00000171453	POLR1C	75	32.292	ENSELUG00000012259	polr2c	76	30.045	Esox_lucius
ENSG00000171453	POLR1C	100	76.613	ENSELUG00000013027	polr1c	100	72.046	Esox_lucius
ENSG00000171453	POLR1C	75	39.583	ENSFCAG00000034622	POLR2C	67	33.333	Felis_catus
ENSG00000171453	POLR1C	100	98.387	ENSFCAG00000009735	POLR1C	100	97.297	Felis_catus
ENSG00000171453	POLR1C	75	37.500	ENSFALG00000006931	POLR2C	67	31.795	Ficedula_albicollis
ENSG00000171453	POLR1C	98	85.950	ENSFALG00000012111	POLR1C	100	82.043	Ficedula_albicollis
ENSG00000171453	POLR1C	100	97.581	ENSFDAG00000008428	POLR1C	100	96.532	Fukomys_damarensis
ENSG00000171453	POLR1C	65	38.095	ENSFDAG00000008641	POLR2C	62	34.463	Fukomys_damarensis
ENSG00000171453	POLR1C	95	30.714	ENSFHEG00000020739	polr2c	87	30.714	Fundulus_heteroclitus
ENSG00000171453	POLR1C	89	80.000	ENSFHEG00000013867	-	87	70.950	Fundulus_heteroclitus
ENSG00000171453	POLR1C	100	72.581	ENSFHEG00000000262	polr1c	100	72.054	Fundulus_heteroclitus
ENSG00000171453	POLR1C	95	30.000	ENSGMOG00000004203	polr2c	87	30.000	Gadus_morhua
ENSG00000171453	POLR1C	100	75.806	ENSGMOG00000013878	polr1c	100	71.605	Gadus_morhua
ENSG00000171453	POLR1C	75	37.500	ENSGALG00000001168	POLR2C	67	32.308	Gallus_gallus
ENSG00000171453	POLR1C	99	86.179	ENSGALG00000010349	POLR1C	100	82.370	Gallus_gallus
ENSG00000171453	POLR1C	100	73.077	ENSGAFG00000010153	polr1c	100	72.080	Gambusia_affinis
ENSG00000171453	POLR1C	95	30.714	ENSGAFG00000021951	polr2c	87	30.714	Gambusia_affinis
ENSG00000171453	POLR1C	100	71.525	ENSGACG00000002453	polr1c	98	71.802	Gasterosteus_aculeatus
ENSG00000171453	POLR1C	75	33.333	ENSGACG00000002194	polr2c	67	31.282	Gasterosteus_aculeatus
ENSG00000171453	POLR1C	63	38.272	ENSGAGG00000016942	POLR2C	58	35.057	Gopherus_agassizii
ENSG00000171453	POLR1C	100	87.097	ENSGAGG00000010640	POLR1C	100	85.549	Gopherus_agassizii
ENSG00000171453	POLR1C	100	100.000	ENSGGOG00000010903	POLR1C	100	100.000	Gorilla_gorilla
ENSG00000171453	POLR1C	75	39.583	ENSGGOG00000012415	POLR2C	67	33.333	Gorilla_gorilla
ENSG00000171453	POLR1C	95	30.000	ENSHBUG00000023040	polr2c	87	30.000	Haplochromis_burtoni
ENSG00000171453	POLR1C	100	65.130	ENSHBUG00000017816	polr1c	100	65.130	Haplochromis_burtoni
ENSG00000171453	POLR1C	75	39.583	ENSHGLG00000013465	POLR2C	67	33.333	Heterocephalus_glaber_female
ENSG00000171453	POLR1C	100	97.581	ENSHGLG00000019441	POLR1C	100	95.665	Heterocephalus_glaber_female
ENSG00000171453	POLR1C	75	39.583	ENSHGLG00100011949	POLR2C	67	33.333	Heterocephalus_glaber_male
ENSG00000171453	POLR1C	100	97.581	ENSHGLG00100005970	POLR1C	100	95.665	Heterocephalus_glaber_male
ENSG00000171453	POLR1C	95	30.000	ENSHCOG00000007066	polr2c	87	30.000	Hippocampus_comes
ENSG00000171453	POLR1C	99	69.759	ENSHCOG00000002179	polr1c	99	68.786	Hippocampus_comes
ENSG00000171453	POLR1C	75	35.417	ENSIPUG00000009231	polr2c	87	30.357	Ictalurus_punctatus
ENSG00000171453	POLR1C	100	79.839	ENSIPUG00000024464	polr1c	97	73.964	Ictalurus_punctatus
ENSG00000171453	POLR1C	75	39.583	ENSSTOG00000015150	-	67	33.333	Ictidomys_tridecemlineatus
ENSG00000171453	POLR1C	100	98.625	ENSSTOG00000010631	POLR1C	100	98.266	Ictidomys_tridecemlineatus
ENSG00000171453	POLR1C	73	34.653	ENSSTOG00000031354	-	60	34.286	Ictidomys_tridecemlineatus
ENSG00000171453	POLR1C	100	97.581	ENSJJAG00000023110	Polr1c	100	96.243	Jaculus_jaculus
ENSG00000171453	POLR1C	75	39.583	ENSJJAG00000023057	Polr2c	67	33.333	Jaculus_jaculus
ENSG00000171453	POLR1C	95	31.071	ENSKMAG00000016196	polr2c	87	31.071	Kryptolebias_marmoratus
ENSG00000171453	POLR1C	100	75.000	ENSKMAG00000014305	polr1c	99	72.203	Kryptolebias_marmoratus
ENSG00000171453	POLR1C	100	72.656	ENSLBEG00000014925	polr1c	100	71.510	Labrus_bergylta
ENSG00000171453	POLR1C	95	30.000	ENSLBEG00000007369	polr2c	87	30.000	Labrus_bergylta
ENSG00000171453	POLR1C	97	70.732	ENSLACG00000012567	POLR1C	98	63.253	Latimeria_chalumnae
ENSG00000171453	POLR1C	100	82.258	ENSLOCG00000016710	polr1c	96	75.216	Lepisosteus_oculatus
ENSG00000171453	POLR1C	95	31.429	ENSLOCG00000003215	polr2c	90	30.070	Lepisosteus_oculatus
ENSG00000171453	POLR1C	100	96.918	ENSLAFG00000026248	POLR1C	100	96.678	Loxodonta_africana
ENSG00000171453	POLR1C	75	39.583	ENSLAFG00000027230	POLR2C	68	32.821	Loxodonta_africana
ENSG00000171453	POLR1C	75	39.583	ENSMFAG00000016861	POLR2C	67	33.333	Macaca_fascicularis
ENSG00000171453	POLR1C	100	98.969	ENSMFAG00000046295	POLR1C	100	98.844	Macaca_fascicularis
ENSG00000171453	POLR1C	75	39.583	ENSMMUG00000020474	POLR2C	67	33.333	Macaca_mulatta
ENSG00000171453	POLR1C	100	98.969	ENSMMUG00000015192	POLR1C	100	98.844	Macaca_mulatta
ENSG00000171453	POLR1C	75	39.583	ENSMNEG00000033565	POLR2C	67	33.333	Macaca_nemestrina
ENSG00000171453	POLR1C	100	98.969	ENSMNEG00000028073	POLR1C	100	98.844	Macaca_nemestrina
ENSG00000171453	POLR1C	100	99.313	ENSMLEG00000034818	POLR1C	100	98.844	Mandrillus_leucophaeus
ENSG00000171453	POLR1C	75	39.583	ENSMLEG00000032412	POLR2C	67	33.333	Mandrillus_leucophaeus
ENSG00000171453	POLR1C	100	75.000	ENSMAMG00000008700	polr1c	100	71.795	Mastacembelus_armatus
ENSG00000171453	POLR1C	95	30.357	ENSMAMG00000013205	polr2c	87	30.357	Mastacembelus_armatus
ENSG00000171453	POLR1C	95	30.000	ENSMZEG00005015329	polr2c	87	30.000	Maylandia_zebra
ENSG00000171453	POLR1C	100	75.000	ENSMZEG00005018545	polr1c	100	72.727	Maylandia_zebra
ENSG00000171453	POLR1C	100	78.351	ENSMGAG00000011020	POLR1C	100	78.351	Meleagris_gallopavo
ENSG00000171453	POLR1C	100	96.220	ENSMAUG00000014329	Polr1c	100	95.954	Mesocricetus_auratus
ENSG00000171453	POLR1C	64	31.414	ENSMAUG00000019031	-	72	31.122	Mesocricetus_auratus
ENSG00000171453	POLR1C	100	97.581	ENSMICG00000005027	POLR1C	100	96.959	Microcebus_murinus
ENSG00000171453	POLR1C	75	39.583	ENSMICG00000045178	POLR2C	67	33.333	Microcebus_murinus
ENSG00000171453	POLR1C	100	96.091	ENSMOCG00000017549	Polr1c	100	95.954	Microtus_ochrogaster
ENSG00000171453	POLR1C	76	36.082	ENSMOCG00000013652	Polr2c	66	33.161	Microtus_ochrogaster
ENSG00000171453	POLR1C	100	67.742	ENSMMOG00000005380	polr1c	99	68.243	Mola_mola
ENSG00000171453	POLR1C	95	31.071	ENSMMOG00000010560	polr2c	87	31.071	Mola_mola
ENSG00000171453	POLR1C	75	39.583	ENSMODG00000013540	POLR2C	67	33.333	Monodelphis_domestica
ENSG00000171453	POLR1C	100	91.935	ENSMODG00000018964	POLR1C	100	91.409	Monodelphis_domestica
ENSG00000171453	POLR1C	95	30.357	ENSMALG00000004581	polr2c	87	30.357	Monopterus_albus
ENSG00000171453	POLR1C	100	76.613	ENSMALG00000011711	polr1c	99	72.542	Monopterus_albus
ENSG00000171453	POLR1C	97	89.399	MGP_CAROLIEiJ_G0021662	Polr1c	100	94.615	Mus_caroli
ENSG00000171453	POLR1C	76	37.113	MGP_CAROLIEiJ_G0031409	Polr2c	67	33.846	Mus_caroli
ENSG00000171453	POLR1C	76	37.113	ENSMUSG00000031783	Polr2c	67	33.846	Mus_musculus
ENSG00000171453	POLR1C	100	95.161	ENSMUSG00000067148	Polr1c	100	94.615	Mus_musculus
ENSG00000171453	POLR1C	100	94.355	MGP_PahariEiJ_G0020654	Polr1c	100	93.846	Mus_pahari
ENSG00000171453	POLR1C	76	37.113	MGP_PahariEiJ_G0023007	Polr2c	67	33.846	Mus_pahari
ENSG00000171453	POLR1C	100	95.161	MGP_SPRETEiJ_G0022574	Polr1c	100	95.000	Mus_spretus
ENSG00000171453	POLR1C	76	37.113	MGP_SPRETEiJ_G0032528	Polr2c	67	33.846	Mus_spretus
ENSG00000171453	POLR1C	100	98.387	ENSMPUG00000012916	POLR1C	91	97.399	Mustela_putorius_furo
ENSG00000171453	POLR1C	75	39.583	ENSMPUG00000004483	POLR2C	67	33.333	Mustela_putorius_furo
ENSG00000171453	POLR1C	75	39.583	ENSMLUG00000025422	-	67	33.333	Myotis_lucifugus
ENSG00000171453	POLR1C	75	36.842	ENSMLUG00000029495	-	67	31.443	Myotis_lucifugus
ENSG00000171453	POLR1C	100	98.625	ENSMLUG00000017751	POLR1C	99	98.555	Myotis_lucifugus
ENSG00000171453	POLR1C	75	39.583	ENSMLUG00000015833	-	67	33.333	Myotis_lucifugus
ENSG00000171453	POLR1C	100	95.954	ENSNGAG00000023487	Polr1c	100	95.954	Nannospalax_galili
ENSG00000171453	POLR1C	75	39.583	ENSNGAG00000012249	-	67	33.333	Nannospalax_galili
ENSG00000171453	POLR1C	75	34.375	ENSNBRG00000003952	polr2c	53	30.392	Neolamprologus_brichardi
ENSG00000171453	POLR1C	100	74.194	ENSNBRG00000018742	polr1c	100	73.064	Neolamprologus_brichardi
ENSG00000171453	POLR1C	66	31.000	ENSNLEG00000003034	POLR2C	75	31.000	Nomascus_leucogenys
ENSG00000171453	POLR1C	100	100.000	ENSNLEG00000004035	POLR1C	100	99.422	Nomascus_leucogenys
ENSG00000171453	POLR1C	75	33.333	ENSMEUG00000014741	POLR2C	67	30.769	Notamacropus_eugenii
ENSG00000171453	POLR1C	100	92.742	ENSMEUG00000006778	POLR1C	100	78.902	Notamacropus_eugenii
ENSG00000171453	POLR1C	59	42.466	ENSOPRG00000006979	POLR2C	67	31.188	Ochotona_princeps
ENSG00000171453	POLR1C	100	95.968	ENSOPRG00000000145	POLR1C	100	94.403	Ochotona_princeps
ENSG00000171453	POLR1C	75	93.151	ENSODEG00000017109	-	100	93.151	Octodon_degus
ENSG00000171453	POLR1C	100	95.968	ENSODEG00000015831	-	100	94.798	Octodon_degus
ENSG00000171453	POLR1C	75	39.583	ENSODEG00000016934	POLR2C	67	33.333	Octodon_degus
ENSG00000171453	POLR1C	95	30.000	ENSONIG00000010914	polr2c	87	30.000	Oreochromis_niloticus
ENSG00000171453	POLR1C	100	72.656	ENSONIG00000013133	polr1c	98	72.934	Oreochromis_niloticus
ENSG00000171453	POLR1C	50	36.923	ENSOANG00000009337	POLR2C	64	32.911	Ornithorhynchus_anatinus
ENSG00000171453	POLR1C	100	87.903	ENSOANG00000003043	POLR1C	100	85.549	Ornithorhynchus_anatinus
ENSG00000171453	POLR1C	100	98.387	ENSOCUG00000005504	POLR1C	99	97.977	Oryctolagus_cuniculus
ENSG00000171453	POLR1C	75	39.583	ENSOCUG00000014984	POLR2C	67	33.333	Oryctolagus_cuniculus
ENSG00000171453	POLR1C	95	30.714	ENSORLG00000015108	polr2c	87	30.714	Oryzias_latipes
ENSG00000171453	POLR1C	100	71.774	ENSORLG00000019743	polr1c	99	69.741	Oryzias_latipes
ENSG00000171453	POLR1C	100	72.581	ENSORLG00020006489	POLR1C	99	70.317	Oryzias_latipes_hni
ENSG00000171453	POLR1C	95	31.429	ENSORLG00020013566	polr2c	87	31.429	Oryzias_latipes_hni
ENSG00000171453	POLR1C	77	58.952	ENSORLG00020005555	polr1c	68	58.952	Oryzias_latipes_hni
ENSG00000171453	POLR1C	95	30.714	ENSORLG00015003751	polr2c	87	30.714	Oryzias_latipes_hsok
ENSG00000171453	POLR1C	100	70.513	ENSORLG00015013322	polr1c	99	69.741	Oryzias_latipes_hsok
ENSG00000171453	POLR1C	95	30.714	ENSOMEG00000019444	polr2c	87	30.714	Oryzias_melastigma
ENSG00000171453	POLR1C	98	71.972	ENSOMEG00000016527	polr1c	98	70.725	Oryzias_melastigma
ENSG00000171453	POLR1C	75	39.583	ENSOGAG00000016866	POLR2C	67	33.846	Otolemur_garnettii
ENSG00000171453	POLR1C	100	96.032	ENSOGAG00000016318	POLR1C	100	95.115	Otolemur_garnettii
ENSG00000171453	POLR1C	75	39.583	ENSOARG00000000302	POLR2C	67	33.333	Ovis_aries
ENSG00000171453	POLR1C	100	97.595	ENSOARG00000007503	POLR1C	100	97.110	Ovis_aries
ENSG00000171453	POLR1C	57	31.953	ENSPPAG00000042822	POLR2C	62	31.953	Pan_paniscus
ENSG00000171453	POLR1C	100	100.000	ENSPPAG00000043678	POLR1C	100	100.000	Pan_paniscus
ENSG00000171453	POLR1C	75	39.583	ENSPPRG00000003215	POLR2C	67	33.333	Panthera_pardus
ENSG00000171453	POLR1C	100	98.387	ENSPPRG00000009760	POLR1C	100	97.635	Panthera_pardus
ENSG00000171453	POLR1C	70	37.778	ENSPTIG00000010297	POLR2C	63	33.880	Panthera_tigris_altaica
ENSG00000171453	POLR1C	100	98.387	ENSPTIG00000014813	POLR1C	100	97.635	Panthera_tigris_altaica
ENSG00000171453	POLR1C	100	100.000	ENSPTRG00000018202	POLR1C	100	100.000	Pan_troglodytes
ENSG00000171453	POLR1C	75	39.583	ENSPTRG00000008157	POLR2C	67	33.333	Pan_troglodytes
ENSG00000171453	POLR1C	75	39.583	ENSPANG00000006264	POLR2C	67	33.333	Papio_anubis
ENSG00000171453	POLR1C	100	99.313	ENSPANG00000009025	POLR1C	100	98.986	Papio_anubis
ENSG00000171453	POLR1C	100	80.645	ENSPKIG00000009858	polr1c	100	75.216	Paramormyrops_kingsleyae
ENSG00000171453	POLR1C	75	33.333	ENSPKIG00000005228	polr2c	67	31.795	Paramormyrops_kingsleyae
ENSG00000171453	POLR1C	63	38.272	ENSPSIG00000016112	POLR2C	60	34.483	Pelodiscus_sinensis
ENSG00000171453	POLR1C	100	86.290	ENSPSIG00000012580	POLR1C	94	83.815	Pelodiscus_sinensis
ENSG00000171453	POLR1C	75	35.417	ENSPMGG00000021249	polr2c	74	34.715	Periophthalmus_magnuspinnatus
ENSG00000171453	POLR1C	100	74.194	ENSPMGG00000012121	polr1c	99	71.525	Periophthalmus_magnuspinnatus
ENSG00000171453	POLR1C	100	95.876	ENSPEMG00000006970	Polr1c	100	95.665	Peromyscus_maniculatus_bairdii
ENSG00000171453	POLR1C	76	37.113	ENSPEMG00000014204	Polr2c	67	33.846	Peromyscus_maniculatus_bairdii
ENSG00000171453	POLR1C	100	80.645	ENSPMAG00000005560	polr1c	98	72.303	Petromyzon_marinus
ENSG00000171453	POLR1C	75	35.417	ENSPMAG00000004827	polr2c	81	31.472	Petromyzon_marinus
ENSG00000171453	POLR1C	100	91.935	ENSPCIG00000028137	POLR1C	100	91.554	Phascolarctos_cinereus
ENSG00000171453	POLR1C	75	39.583	ENSPCIG00000015111	POLR2C	67	33.333	Phascolarctos_cinereus
ENSG00000171453	POLR1C	100	73.077	ENSPFOG00000014342	POLR1C	100	72.650	Poecilia_formosa
ENSG00000171453	POLR1C	100	73.077	ENSPFOG00000014357	polr1c	98	72.650	Poecilia_formosa
ENSG00000171453	POLR1C	95	30.714	ENSPFOG00000024666	polr2c	87	30.714	Poecilia_formosa
ENSG00000171453	POLR1C	89	80.800	ENSPLAG00000003902	polr1c	99	80.153	Poecilia_latipinna
ENSG00000171453	POLR1C	95	30.714	ENSPLAG00000019750	polr2c	87	30.714	Poecilia_latipinna
ENSG00000171453	POLR1C	82	65.272	ENSPLAG00000004111	polr1c	99	65.272	Poecilia_latipinna
ENSG00000171453	POLR1C	95	30.714	ENSPMEG00000001741	polr2c	87	30.714	Poecilia_mexicana
ENSG00000171453	POLR1C	100	73.387	ENSPMEG00000011877	-	100	72.650	Poecilia_mexicana
ENSG00000171453	POLR1C	100	73.387	ENSPMEG00000008420	polr1c	100	72.650	Poecilia_mexicana
ENSG00000171453	POLR1C	100	74.351	ENSPREG00000007985	polr1c	100	73.487	Poecilia_reticulata
ENSG00000171453	POLR1C	59	31.720	ENSPREG00000003090	polr2c	63	31.720	Poecilia_reticulata
ENSG00000171453	POLR1C	100	100.000	ENSPPYG00000016645	POLR1C	100	99.711	Pongo_abelii
ENSG00000171453	POLR1C	75	39.583	ENSPPYG00000007390	POLR2C	67	33.333	Pongo_abelii
ENSG00000171453	POLR1C	50	33.121	ENSPCAG00000002423	POLR2C	64	33.121	Procavia_capensis
ENSG00000171453	POLR1C	75	39.583	ENSPCOG00000017282	POLR2C	67	33.333	Propithecus_coquereli
ENSG00000171453	POLR1C	100	99.194	ENSPCOG00000024628	POLR1C	100	97.297	Propithecus_coquereli
ENSG00000171453	POLR1C	75	39.583	ENSPVAG00000001399	POLR2C	67	33.333	Pteropus_vampyrus
ENSG00000171453	POLR1C	100	88.150	ENSPVAG00000005689	POLR1C	100	88.150	Pteropus_vampyrus
ENSG00000171453	POLR1C	100	72.656	ENSPNYG00000003620	polr1c	99	72.206	Pundamilia_nyererei
ENSG00000171453	POLR1C	95	30.000	ENSPNYG00000003756	polr2c	87	30.000	Pundamilia_nyererei
ENSG00000171453	POLR1C	100	79.839	ENSPNAG00000008443	polr1c	99	73.043	Pygocentrus_nattereri
ENSG00000171453	POLR1C	95	30.714	ENSPNAG00000012133	polr2c	87	30.714	Pygocentrus_nattereri
ENSG00000171453	POLR1C	76	37.113	ENSRNOG00000015720	Polr2c	67	33.846	Rattus_norvegicus
ENSG00000171453	POLR1C	100	94.509	ENSRNOG00000019079	Polr1c	100	94.509	Rattus_norvegicus
ENSG00000171453	POLR1C	75	39.583	ENSRBIG00000026549	POLR2C	67	33.333	Rhinopithecus_bieti
ENSG00000171453	POLR1C	100	100.000	ENSRBIG00000007155	POLR1C	100	98.986	Rhinopithecus_bieti
ENSG00000171453	POLR1C	100	100.000	ENSRROG00000000257	POLR1C	100	99.324	Rhinopithecus_roxellana
ENSG00000171453	POLR1C	75	39.583	ENSRROG00000045745	POLR2C	67	33.333	Rhinopithecus_roxellana
ENSG00000171453	POLR1C	54	42.647	YIL021W	RPB3	57	30.928	Saccharomyces_cerevisiae
ENSG00000171453	POLR1C	100	47.244	YPR110C	RPC40	96	46.154	Saccharomyces_cerevisiae
ENSG00000171453	POLR1C	100	99.313	ENSSBOG00000025735	POLR1C	100	98.710	Saimiri_boliviensis_boliviensis
ENSG00000171453	POLR1C	75	39.583	ENSSBOG00000030004	POLR2C	67	33.333	Saimiri_boliviensis_boliviensis
ENSG00000171453	POLR1C	100	82.948	ENSSHAG00000014456	POLR1C	100	82.948	Sarcophilus_harrisii
ENSG00000171453	POLR1C	100	82.258	ENSSFOG00015019860	polr1c	100	74.352	Scleropages_formosus
ENSG00000171453	POLR1C	95	31.071	ENSSFOG00015023460	polr2c	87	31.071	Scleropages_formosus
ENSG00000171453	POLR1C	100	74.194	ENSSMAG00000018865	polr1c	99	72.754	Scophthalmus_maximus
ENSG00000171453	POLR1C	95	30.000	ENSSMAG00000002827	polr2c	71	30.714	Scophthalmus_maximus
ENSG00000171453	POLR1C	95	30.357	ENSSDUG00000003354	polr2c	87	30.357	Seriola_dumerili
ENSG00000171453	POLR1C	100	75.806	ENSSDUG00000015745	polr1c	100	72.391	Seriola_dumerili
ENSG00000171453	POLR1C	100	75.806	ENSSLDG00000018285	polr1c	100	72.054	Seriola_lalandi_dorsalis
ENSG00000171453	POLR1C	95	30.357	ENSSLDG00000003555	polr2c	87	30.357	Seriola_lalandi_dorsalis
ENSG00000171453	POLR1C	99	80.277	ENSSPUG00000011822	POLR1C	99	79.070	Sphenodon_punctatus
ENSG00000171453	POLR1C	75	38.542	ENSSPUG00000012934	POLR2C	67	32.308	Sphenodon_punctatus
ENSG00000171453	POLR1C	100	73.559	ENSSPAG00000022369	polr1c	100	72.365	Stegastes_partitus
ENSG00000171453	POLR1C	75	34.375	ENSSPAG00000005108	polr2c	76	30.493	Stegastes_partitus
ENSG00000171453	POLR1C	75	39.583	ENSSSCG00000025454	POLR2C	67	33.333	Sus_scrofa
ENSG00000171453	POLR1C	100	97.581	ENSSSCG00000028007	POLR1C	99	97.110	Sus_scrofa
ENSG00000171453	POLR1C	99	85.366	ENSTGUG00000009159	POLR1C	99	82.388	Taeniopygia_guttata
ENSG00000171453	POLR1C	75	37.500	ENSTGUG00000004996	POLR2C	67	31.795	Taeniopygia_guttata
ENSG00000171453	POLR1C	75	37.500	ENSTGUG00000017035	-	77	33.333	Taeniopygia_guttata
ENSG00000171453	POLR1C	95	30.714	ENSTRUG00000004676	polr2c	87	30.714	Takifugu_rubripes
ENSG00000171453	POLR1C	100	70.400	ENSTRUG00000006264	polr1c	99	69.828	Takifugu_rubripes
ENSG00000171453	POLR1C	95	30.714	ENSTNIG00000008851	polr2c	87	30.714	Tetraodon_nigroviridis
ENSG00000171453	POLR1C	61	98.876	ENSTBEG00000002254	POLR1C	100	98.876	Tupaia_belangeri
ENSG00000171453	POLR1C	75	38.542	ENSTBEG00000009442	POLR2C	67	32.821	Tupaia_belangeri
ENSG00000171453	POLR1C	53	32.484	ENSTTRG00000010060	POLR2C	64	32.484	Tursiops_truncatus
ENSG00000171453	POLR1C	90	95.057	ENSTTRG00000006344	POLR1C	76	95.057	Tursiops_truncatus
ENSG00000171453	POLR1C	75	39.583	ENSUAMG00000014170	POLR2C	67	33.333	Ursus_americanus
ENSG00000171453	POLR1C	100	98.387	ENSUAMG00000025602	POLR1C	100	97.399	Ursus_americanus
ENSG00000171453	POLR1C	100	98.387	ENSUMAG00000005938	POLR1C	100	97.399	Ursus_maritimus
ENSG00000171453	POLR1C	63	39.506	ENSUMAG00000021686	POLR2C	63	34.483	Ursus_maritimus
ENSG00000171453	POLR1C	75	39.583	ENSVVUG00000023516	-	65	32.990	Vulpes_vulpes
ENSG00000171453	POLR1C	100	97.581	ENSVVUG00000028922	POLR1C	100	97.297	Vulpes_vulpes
ENSG00000171453	POLR1C	100	79.839	ENSXETG00000010882	polr1c	100	77.522	Xenopus_tropicalis
ENSG00000171453	POLR1C	64	35.106	ENSXETG00000013784	polr2c	67	32.990	Xenopus_tropicalis
ENSG00000171453	POLR1C	95	30.714	ENSXCOG00000020734	polr2c	87	30.714	Xiphophorus_couchianus
ENSG00000171453	POLR1C	100	74.434	ENSXCOG00000014185	polr1c	100	73.276	Xiphophorus_couchianus
ENSG00000171453	POLR1C	100	73.718	ENSXMAG00000015076	polr1c	100	72.934	Xiphophorus_maculatus
ENSG00000171453	POLR1C	95	30.714	ENSXMAG00000015984	polr2c	87	30.714	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0001056	RNA polymerase III activity	21873635.	IBA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	9540830.	TAS	Function
GO:0005515	protein binding	16189514.21988832.25416956.27107012.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005666	RNA polymerase III complex	21873635.	IBA	Component
GO:0005666	RNA polymerase III complex	24107381.	IDA	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006360	transcription by RNA polymerase I	9540830.	TAS	Process
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0006383	transcription by RNA polymerase III	-	IEA	Process
GO:0032481	positive regulation of type I interferon production	-	TAS	Process
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process
GO:0046983	protein dimerization activity	-	IEA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr6	43517372	Missense_Mutation	novel	E46K	0.05
ACC	chr6	43520980	Missense_Mutation	novel	R285I	0.36
BLCA	chr6	43521008	Missense_Mutation	novel	K294N	0.2
BLCA	chr6	43520164	Missense_Mutation	NA	E161K	0.41
BLCA	chr6	43517081	5'UTR	novel		0.23
BLCA	chr6	43520999	Missense_Mutation	novel	E291D	0.23
BLCA	chr6	43521246	Silent	novel	L329L	0.28
BLCA	chr6	43520391	Missense_Mutation	NA	E207K	0.19
BLCA	chr6	43520083	Missense_Mutation	novel	E134Q	0.25
BRCA	chr6	43517177	Missense_Mutation	rs745593101	N23S	0.22
BRCA	chr6	43519423	Nonsense_Mutation	NA	R78*	0.26	RNA_pol_A_bac
BRCA	chr6	43517129	Missense_Mutation	novel	V7A	0.05
BRCA	chr6	43520701	Silent	NA	P244P	0.24
CESC	chr6	43517102	5'UTR	novel		0.22
CESC	chr6	43517075	5'UTR	novel		0.79
CESC	chr6	43519381	Missense_Mutation	NA	D64H	0.46	RNA_pol_A_bac
CESC	chr6	43517174	Missense_Mutation	rs149529196	R22H	0.27
CESC	chr6	43520387	Silent	novel	G205G	0.37
CESC	chr6	43521263	Missense_Mutation	rs777698504	R335H	0.25
COAD	chr6	43521362	3'UTR	novel		0.14
COAD	chr6	43520064	Splice_Site	novel	X128_splice	0.38
COAD	chr6	43520412	Missense_Mutation	novel	C214R	0.42
COAD	chr6	43520654	Missense_Mutation	novel	A229T	0.33
ESCA	chr6	43520362	In_Frame_Del	novel	L198del	0.24
ESCA	chr6	43517116	Missense_Mutation	novel	A3S	0.58
ESCA	chr6	43520300	Frame_Shift_Del	novel	*L178Wfs76**	0.28
GBM	chr6	43519399	Missense_Mutation	novel	A70T	0.16	RNA_pol_A_bac
GBM	chr6	43521230	Frame_Shift_Ins	novel	*E324Dfs16**	0.11
GBM	chr6	43519729	Missense_Mutation	novel	K91N	0.08	RNA_pol_A_bac
GBM	chr6	43520744	Missense_Mutation	novel	P259S	0.42
GBM	chr6	43520310	Missense_Mutation	novel	N180H	0.05
HNSC	chr6	43521365	3'UTR	novel		0.2
HNSC	chr6	43521218	Missense_Mutation	novel	V320E	0.19
LAML	chr6	43517126	Missense_Mutation	NA	A6V	0.33
LIHC	chr6	43519441	Splice_Site	novel	X83_splice	0.33
LUAD	chr6	43521375	3'UTR	novel		0.08
LUAD	chr6	43521377	3'UTR	novel		0.08
LUAD	chr6	43520975	Silent	NA	F283F	0.27
OV	chr6	43521499	3'UTR	novel		0.38
OV	chr6	43519836	Frame_Shift_Del	novel	*G128Efs8**	0.25
PRAD	chr6	43517146	Missense_Mutation	NA	R13G	0.07
PRAD	chr6	43519718	Missense_Mutation	novel	A88T	0.39	RNA_pol_A_bac
READ	chr6	43521033	Nonsense_Mutation	rs563473186	R303*	0.26
READ	chr6	43521357	3'UTR	novel		0.4
SARC	chr6	43521435	3'UTR	novel		0.27
SKCM	chr6	43517081	5'UTR	rs748148068		0.62
SKCM	chr6	43517128	Missense_Mutation	rs775143492	V7M	0.24
SKCM	chr6	43519338	Silent	novel	F49F	0.28
SKCM	chr6	43521267	Silent	novel	F336F	0.55
SKCM	chr6	43517130	Silent	NA	V7V	0.28
SKCM	chr6	43517131	Missense_Mutation	rs201071477	E8K	0.28
STAD	chr6	43520130	Missense_Mutation	novel	N149K	0.31
STAD	chr6	43520737	Nonsense_Mutation	NA	C256*	0.28
STAD	chr6	43521001	Missense_Mutation	NA	K292M	0.05
STAD	chr6	43520640	Missense_Mutation	NA	K224T	0.11
STAD	chr6	43520331	Missense_Mutation	novel	E187Q	0.25
UCEC	chr6	43520164	Missense_Mutation	NA	E161K	0.33
UCEC	chr6	43520083	Nonsense_Mutation	novel	E134*	0.34
UCEC	chr6	43520982	Nonsense_Mutation	novel	E286*	0.43
UCEC	chr6	43520169	Silent	novel	L162L	0.36
UCEC	chr6	43519743	Missense_Mutation	rs780090128	N96S	0.2	RNA_pol_A_bac
UCEC	chr6	43520344	Missense_Mutation	rs373046018	R191Q	0.24
UCEC	chr6	43520747	Missense_Mutation	novel	G260C	0.1
UCEC	chr6	43520400	Silent	novel	L210L	0.3
UCEC	chr6	43521250	Missense_Mutation	novel	G331R	0.27
UCEC	chr6	43520074	Nonsense_Mutation	novel	E131*	0.52
UCEC	chr6	43521396	3'UTR	novel		0.57
UCEC	chr6	43520385	Missense_Mutation	novel	G205C	0.06
UCEC	chr6	43519424	Missense_Mutation	rs747204932	R78Q	0.27	RNA_pol_A_bac
UCEC	chr6	43520766	Missense_Mutation	novel	E266V	0.27
UCEC	chr6	43521452	3'UTR	novel		0.31
UCEC	chr6	43519782	Missense_Mutation	rs796052127	R109H	0.48
UCEC	chr6	43520104	Missense_Mutation	rs148385032	R141C	0.21
UCEC	chr6	43521038	Silent	novel	D304D	0.22
UCEC	chr6	43519733	Silent	novel	L93L	0.34
UCEC	chr6	43519424	Missense_Mutation	rs747204932	R78Q	0.34	RNA_pol_A_bac

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
COAD	AMP	0.1752	0.005341
READ	AMP	0.2909	0.02906

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00041	Kaplan-Meier Survival Analysis
STAD	0.049	Kaplan-Meier Survival Analysis
SARC	0.0016	Kaplan-Meier Survival Analysis
PRAD	0.019	Kaplan-Meier Survival Analysis
LUSC	0.04	Kaplan-Meier Survival Analysis
KICH	0.0063	Kaplan-Meier Survival Analysis
LIHC	0.0063	Kaplan-Meier Survival Analysis
DLBC	0.0075	Kaplan-Meier Survival Analysis
OV	0.021	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742