EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171824 (Gene tree)
Gene ID: 5394
Gene Symbol: EXOSC10
Alias: PM-Scl|PM/Scl-100|Rrp6p|RRP6|p2|p3|p4|PMSCL2
Full Name: exosome component 10
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 33,298 bases
Position: chr1:11,066,613-11,099,910
Accession: 9138
RBP type: canonical RBP
Summary: (Exosome Component 10) is a Protein Coding gene. Diseases associated with EXOSC10 include Systemic Scleroderma and Childhood Type Dermatomyositis. Among its related pathways are ATP/ITP metabolism and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is EXD1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000307307	HRDC	PF00570.23	2.1e-12	1	1
ENSP00000366135	HRDC	PF00570.23	2.2e-12	1	1
ENSP00000307307	PMC2NT	PF08066.12	1.8e-22	1	1
ENSP00000366135	PMC2NT	PF08066.12	2e-22	1	1
ENSP00000307307	DNA_pol_A_exo1	PF01612.20	4.7e-49	1	1
ENSP00000366135	DNA_pol_A_exo1	PF01612.20	4.7e-49	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23417976	Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.	Wiley Interdiscip Rev RNA	2013 Mar-Apr	Schmidt K	doi: 10.1002/wrna.1155
21135092	The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation.	J Biol Chem	2011 Feb 11	Costello JL	doi: 10.1074/jbc.M110.162826
27402898	Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs.	RNA	2016 Sep	Mukherjee K	doi: 10.1261/rna.051490.115
31165730	SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis.	Nat Commun	2019 Jun 5	Kim M	doi: 10.1038/s41467-019-10350-6.
26612606	Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination.	Wiley Interdiscip Rev RNA	2016 Jan-Feb	Fox MJ	doi: 10.1002/wrna.1317
24106327	Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.	RNA	2013 Dec	Garland W	doi: 10.1261/rna.039388.113
9112227	The behavior of the coiled body in cells infected with adenovirus in vitro.	Mol Biol Rep	1996	Rodrigues SH	-
17938247	Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site.	J Cell Biol	2007 Oct 22	Custodio N	-
17704127	The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein.	Nucleic Acids Res	2007	Stead JA	-
24196955	The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome.	J Biol Chem	2013 Dec 20	Heo DH	doi: 10.1074/jbc.M113.508267
24146636	The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay.	PLoS Genet	2013	Bresson SM	doi: 10.1371/journal.pgen.1003893

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000470611	EXOSC10-205	401	-	-	- (aa)	-	-
ENST00000376936	EXOSC10-202	2808	XM_005263475	ENSP00000366135	885 (aa)	XP_005263532	Q01780
ENST00000304457	EXOSC10-201	2721	-	ENSP00000307307	860 (aa)	-	Q01780
ENST00000469634	EXOSC10-204	2361	-	-	- (aa)	-	-
ENST00000474216	EXOSC10-207	2007	-	-	- (aa)	-	-
ENST00000490565	EXOSC10-210	421	-	-	- (aa)	-	-
ENST00000485606	EXOSC10-209	459	-	-	- (aa)	-	-
ENST00000478271	EXOSC10-208	608	-	-	- (aa)	-	-
ENST00000498576	EXOSC10-211	486	-	-	- (aa)	-	-
ENST00000472078	EXOSC10-206	412	-	-	- (aa)	-	-
ENST00000460196	EXOSC10-203	622	-	ENSP00000465008	124 (aa)	-	K7EJ37

Gene Model

Click here to download ENSG00000171824's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000171824	Pulse Wave Analysis	9.874e-007	-
ENSG00000171824	Pulse Wave Analysis	3.329e-007	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000171824	rs534975221	1	11097186	G	Intraocular pressure	29617998	[0.6-0.91] unit increase	0.7542	EFO_0004695
ENSG00000171824	rs12569242	1	11067454	?	Heel bone mineral density	30048462	[0.017-0.026] unit decrease	0.0215932	EFO_0009270
ENSG00000171824	rs2791655	1	11068597	G	Heel bone mineral density	30598549	[0.015-0.023] unit decrease	0.0186244	EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171824's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171824	EXOSC10	98	62.273	ENSAPOG00000013304	exosc10	97	62.273	Acanthochromis_polyacanthus
ENSG00000171824	EXOSC10	100	93.548	ENSAMEG00000009546	EXOSC10	100	89.741	Ailuropoda_melanoleuca
ENSG00000171824	EXOSC10	96	58.382	ENSACIG00000020455	exosc10	96	59.785	Amphilophus_citrinellus
ENSG00000171824	EXOSC10	98	60.855	ENSAOCG00000018823	exosc10	97	60.970	Amphiprion_ocellaris
ENSG00000171824	EXOSC10	98	61.862	ENSAPEG00000017786	exosc10	97	61.034	Amphiprion_percula
ENSG00000171824	EXOSC10	97	62.557	ENSATEG00000017271	exosc10	97	62.557	Anabas_testudineus
ENSG00000171824	EXOSC10	98	74.023	ENSAPLG00000006652	EXOSC10	100	74.023	Anas_platyrhynchos
ENSG00000171824	EXOSC10	100	90.734	ENSANAG00000031112	EXOSC10	100	90.734	Aotus_nancymaae
ENSG00000171824	EXOSC10	98	61.802	ENSACLG00000025226	exosc10	97	61.608	Astatotilapia_calliptera
ENSG00000171824	EXOSC10	100	59.086	ENSAMXG00000014510	exosc10	100	59.086	Astyanax_mexicanus
ENSG00000171824	EXOSC10	100	92.742	ENSBTAG00000002590	EXOSC10	99	91.655	Bos_taurus
ENSG00000171824	EXOSC10	75	34.226	WBGene00000796	crn-3	77	33.666	Caenorhabditis_elegans
ENSG00000171824	EXOSC10	100	95.968	ENSCJAG00000002327	EXOSC10	100	95.480	Callithrix_jacchus
ENSG00000171824	EXOSC10	100	91.129	ENSCAFG00000016721	EXOSC10	98	89.515	Canis_familiaris
ENSG00000171824	EXOSC10	100	91.129	ENSCAFG00020002481	EXOSC10	98	89.515	Canis_lupus_dingo
ENSG00000171824	EXOSC10	100	93.548	ENSCHIG00000020022	EXOSC10	100	85.979	Capra_hircus
ENSG00000171824	EXOSC10	100	86.569	ENSTSYG00000006937	EXOSC10	100	86.569	Carlito_syrichta
ENSG00000171824	EXOSC10	96	89.199	ENSCAPG00000006494	EXOSC10	100	89.199	Cavia_aperea
ENSG00000171824	EXOSC10	100	90.323	ENSCPOG00000011628	EXOSC10	100	88.386	Cavia_porcellus
ENSG00000171824	EXOSC10	100	88.939	ENSCCAG00000023223	EXOSC10	100	95.636	Cebus_capucinus
ENSG00000171824	EXOSC10	100	98.387	ENSCATG00000039000	EXOSC10	100	98.140	Cercocebus_atys
ENSG00000171824	EXOSC10	100	92.742	ENSCLAG00000005283	EXOSC10	100	88.269	Chinchilla_lanigera
ENSG00000171824	EXOSC10	100	97.627	ENSCSAG00000000788	EXOSC10	100	97.627	Chlorocebus_sabaeus
ENSG00000171824	EXOSC10	100	91.935	ENSCHOG00000012713	EXOSC10	100	83.676	Choloepus_hoffmanni
ENSG00000171824	EXOSC10	98	75.172	ENSCPBG00000022004	EXOSC10	96	75.172	Chrysemys_picta_bellii
ENSG00000171824	EXOSC10	68	47.563	ENSCSAVG00000009049	-	100	47.563	Ciona_savignyi
ENSG00000171824	EXOSC10	100	97.674	ENSCANG00000042813	EXOSC10	100	97.674	Colobus_angolensis_palliatus
ENSG00000171824	EXOSC10	100	90.323	ENSCGRG00001018469	Exosc10	100	88.734	Cricetulus_griseus_chok1gshd
ENSG00000171824	EXOSC10	100	88.710	ENSCGRG00000002278	Exosc10	100	88.502	Cricetulus_griseus_crigri
ENSG00000171824	EXOSC10	99	60.113	ENSCSEG00000005346	exosc10	97	60.113	Cynoglossus_semilaevis
ENSG00000171824	EXOSC10	99	61.333	ENSCVAG00000016429	exosc10	99	61.038	Cyprinodon_variegatus
ENSG00000171824	EXOSC10	97	59.393	ENSDARG00000037708	exosc10	98	59.444	Danio_rerio
ENSG00000171824	EXOSC10	100	89.516	ENSDNOG00000011301	EXOSC10	100	88.501	Dasypus_novemcinctus
ENSG00000171824	EXOSC10	100	92.742	ENSDORG00000003769	Exosc10	100	85.482	Dipodomys_ordii
ENSG00000171824	EXOSC10	68	41.196	FBgn0038269	Rrp6	63	41.196	Drosophila_melanogaster
ENSG00000171824	EXOSC10	100	86.290	ENSETEG00000000830	EXOSC10	99	84.525	Echinops_telfairi
ENSG00000171824	EXOSC10	72	34.504	ENSEBUG00000004395	exosc10	99	34.351	Eptatretus_burgeri
ENSG00000171824	EXOSC10	100	92.742	ENSEASG00005018716	EXOSC10	100	90.102	Equus_asinus_asinus
ENSG00000171824	EXOSC10	100	92.742	ENSECAG00000011639	EXOSC10	100	90.530	Equus_caballus
ENSG00000171824	EXOSC10	86	83.360	ENSEEUG00000001166	EXOSC10	86	83.360	Erinaceus_europaeus
ENSG00000171824	EXOSC10	98	62.329	ENSELUG00000012870	exosc10	96	62.671	Esox_lucius
ENSG00000171824	EXOSC10	100	94.355	ENSFCAG00000000052	EXOSC10	100	89.327	Felis_catus
ENSG00000171824	EXOSC10	99	70.291	ENSFALG00000010287	EXOSC10	99	70.291	Ficedula_albicollis
ENSG00000171824	EXOSC10	100	89.516	ENSFDAG00000002942	EXOSC10	100	89.443	Fukomys_damarensis
ENSG00000171824	EXOSC10	99	59.688	ENSFHEG00000010678	exosc10	99	59.624	Fundulus_heteroclitus
ENSG00000171824	EXOSC10	84	67.308	ENSGMOG00000006131	exosc10	87	67.810	Gadus_morhua
ENSG00000171824	EXOSC10	97	73.563	ENSGALG00000003086	EXOSC10	95	73.563	Gallus_gallus
ENSG00000171824	EXOSC10	97	61.257	ENSGAFG00000019222	exosc10	98	60.953	Gambusia_affinis
ENSG00000171824	EXOSC10	98	61.416	ENSGACG00000007037	exosc10	97	61.412	Gasterosteus_aculeatus
ENSG00000171824	EXOSC10	99	74.091	ENSGAGG00000000251	EXOSC10	100	74.289	Gopherus_agassizii
ENSG00000171824	EXOSC10	100	100.000	ENSGGOG00000010572	EXOSC10	100	99.548	Gorilla_gorilla
ENSG00000171824	EXOSC10	99	58.065	ENSHBUG00000020328	exosc10	97	58.068	Haplochromis_burtoni
ENSG00000171824	EXOSC10	100	91.129	ENSHGLG00000011944	EXOSC10	100	88.734	Heterocephalus_glaber_female
ENSG00000171824	EXOSC10	100	91.129	ENSHGLG00100014444	EXOSC10	100	88.734	Heterocephalus_glaber_male
ENSG00000171824	EXOSC10	98	60.589	ENSHCOG00000016164	exosc10	98	60.771	Hippocampus_comes
ENSG00000171824	EXOSC10	97	59.842	ENSIPUG00000021971	exosc10	96	59.842	Ictalurus_punctatus
ENSG00000171824	EXOSC10	100	92.742	ENSSTOG00000005459	EXOSC10	100	90.244	Ictidomys_tridecemlineatus
ENSG00000171824	EXOSC10	100	88.710	ENSJJAG00000013716	Exosc10	100	87.805	Jaculus_jaculus
ENSG00000171824	EXOSC10	99	60.358	ENSKMAG00000015540	exosc10	99	60.358	Kryptolebias_marmoratus
ENSG00000171824	EXOSC10	99	61.229	ENSLBEG00000022229	exosc10	98	61.392	Labrus_bergylta
ENSG00000171824	EXOSC10	100	69.291	ENSLACG00000016691	EXOSC10	100	67.667	Latimeria_chalumnae
ENSG00000171824	EXOSC10	97	66.059	ENSLOCG00000006443	exosc10	97	65.906	Lepisosteus_oculatus
ENSG00000171824	EXOSC10	100	91.935	ENSLAFG00000016894	EXOSC10	100	90.428	Loxodonta_africana
ENSG00000171824	EXOSC10	100	98.387	ENSMFAG00000038874	EXOSC10	100	98.023	Macaca_fascicularis
ENSG00000171824	EXOSC10	100	98.387	ENSMMUG00000019322	EXOSC10	100	97.907	Macaca_mulatta
ENSG00000171824	EXOSC10	100	98.387	ENSMNEG00000035812	EXOSC10	100	98.023	Macaca_nemestrina
ENSG00000171824	EXOSC10	100	98.387	ENSMLEG00000025160	EXOSC10	100	98.140	Mandrillus_leucophaeus
ENSG00000171824	EXOSC10	96	61.877	ENSMAMG00000019375	exosc10	97	61.877	Mastacembelus_armatus
ENSG00000171824	EXOSC10	98	61.802	ENSMZEG00005013730	exosc10	97	61.608	Maylandia_zebra
ENSG00000171824	EXOSC10	96	72.992	ENSMGAG00000004665	EXOSC10	99	72.992	Meleagris_gallopavo
ENSG00000171824	EXOSC10	100	91.935	ENSMAUG00000019261	Exosc10	97	93.333	Mesocricetus_auratus
ENSG00000171824	EXOSC10	100	94.355	ENSMICG00000003858	EXOSC10	100	91.870	Microcebus_murinus
ENSG00000171824	EXOSC10	100	91.129	ENSMOCG00000016509	Exosc10	97	93.333	Microtus_ochrogaster
ENSG00000171824	EXOSC10	99	59.727	ENSMMOG00000009265	exosc10	98	59.386	Mola_mola
ENSG00000171824	EXOSC10	100	78.676	ENSMODG00000011194	EXOSC10	100	78.900	Monodelphis_domestica
ENSG00000171824	EXOSC10	97	61.758	ENSMALG00000021322	exosc10	97	61.758	Monopterus_albus
ENSG00000171824	EXOSC10	100	91.935	MGP_CAROLIEiJ_G0026802	Exosc10	97	92.667	Mus_caroli
ENSG00000171824	EXOSC10	100	91.935	ENSMUSG00000017264	Exosc10	97	92.833	Mus_musculus
ENSG00000171824	EXOSC10	100	91.935	MGP_PahariEiJ_G0029150	Exosc10	97	93.333	Mus_pahari
ENSG00000171824	EXOSC10	100	91.935	MGP_SPRETEiJ_G0027795	Exosc10	97	92.667	Mus_spretus
ENSG00000171824	EXOSC10	100	92.742	ENSMPUG00000016434	EXOSC10	97	89.503	Mustela_putorius_furo
ENSG00000171824	EXOSC10	100	89.628	ENSMLUG00000004276	EXOSC10	100	89.628	Myotis_lucifugus
ENSG00000171824	EXOSC10	100	92.742	ENSNGAG00000023829	Exosc10	100	89.431	Nannospalax_galili
ENSG00000171824	EXOSC10	99	59.117	ENSNBRG00000006256	exosc10	97	59.364	Neolamprologus_brichardi
ENSG00000171824	EXOSC10	100	99.194	ENSNLEG00000009539	EXOSC10	100	98.353	Nomascus_leucogenys
ENSG00000171824	EXOSC10	100	77.419	ENSMEUG00000007020	-	74	100.000	Notamacropus_eugenii
ENSG00000171824	EXOSC10	100	90.323	ENSOPRG00000012091	EXOSC10	100	87.739	Ochotona_princeps
ENSG00000171824	EXOSC10	100	91.129	ENSODEG00000013285	EXOSC10	100	88.153	Octodon_degus
ENSG00000171824	EXOSC10	90	63.393	ENSONIG00000002322	exosc10	97	64.073	Oreochromis_niloticus
ENSG00000171824	EXOSC10	99	74.944	ENSOANG00000013322	EXOSC10	99	74.805	Ornithorhynchus_anatinus
ENSG00000171824	EXOSC10	100	89.516	ENSOCUG00000013039	EXOSC10	100	88.751	Oryctolagus_cuniculus
ENSG00000171824	EXOSC10	99	60.155	ENSORLG00000005117	exosc10	100	60.775	Oryzias_latipes
ENSG00000171824	EXOSC10	99	60.491	ENSORLG00020013529	exosc10	97	63.800	Oryzias_latipes_hni
ENSG00000171824	EXOSC10	99	60.647	ENSORLG00015005525	exosc10	98	60.379	Oryzias_latipes_hsok
ENSG00000171824	EXOSC10	99	60.758	ENSOMEG00000003337	exosc10	98	60.296	Oryzias_melastigma
ENSG00000171824	EXOSC10	100	83.333	ENSOGAG00000013662	EXOSC10	100	83.333	Otolemur_garnettii
ENSG00000171824	EXOSC10	100	93.548	ENSOARG00000003668	EXOSC10	100	89.551	Ovis_aries
ENSG00000171824	EXOSC10	100	100.000	ENSPPAG00000038356	EXOSC10	100	99.767	Pan_paniscus
ENSG00000171824	EXOSC10	100	94.355	ENSPPRG00000022976	EXOSC10	100	89.443	Panthera_pardus
ENSG00000171824	EXOSC10	99	94.309	ENSPTIG00000012735	EXOSC10	99	88.015	Panthera_tigris_altaica
ENSG00000171824	EXOSC10	100	99.194	ENSPTRG00000000140	EXOSC10	100	95.706	Pan_troglodytes
ENSG00000171824	EXOSC10	100	96.744	ENSPANG00000026088	EXOSC10	100	96.744	Papio_anubis
ENSG00000171824	EXOSC10	99	59.347	ENSPKIG00000013098	exosc10	97	60.135	Paramormyrops_kingsleyae
ENSG00000171824	EXOSC10	98	73.878	ENSPSIG00000005078	EXOSC10	96	73.878	Pelodiscus_sinensis
ENSG00000171824	EXOSC10	90	60.714	ENSPMGG00000022241	exosc10	97	71.007	Periophthalmus_magnuspinnatus
ENSG00000171824	EXOSC10	81	97.030	ENSPEMG00000007753	Exosc10	98	91.702	Peromyscus_maniculatus_bairdii
ENSG00000171824	EXOSC10	57	52.323	ENSPMAG00000006909	exosc10	100	52.323	Petromyzon_marinus
ENSG00000171824	EXOSC10	92	76.463	ENSPCIG00000004840	EXOSC10	94	84.407	Phascolarctos_cinereus
ENSG00000171824	EXOSC10	98	61.964	ENSPFOG00000004744	exosc10	98	61.659	Poecilia_formosa
ENSG00000171824	EXOSC10	98	61.738	ENSPLAG00000010253	exosc10	98	61.435	Poecilia_latipinna
ENSG00000171824	EXOSC10	98	61.964	ENSPMEG00000005740	exosc10	98	61.659	Poecilia_mexicana
ENSG00000171824	EXOSC10	98	61.374	ENSPREG00000016285	exosc10	98	61.254	Poecilia_reticulata
ENSG00000171824	EXOSC10	100	97.853	ENSPPYG00000001891	EXOSC10	97	97.853	Pongo_abelii
ENSG00000171824	EXOSC10	85	86.741	ENSPCAG00000001583	EXOSC10	100	79.975	Procavia_capensis
ENSG00000171824	EXOSC10	100	93.548	ENSPCOG00000013742	EXOSC10	100	91.405	Propithecus_coquereli
ENSG00000171824	EXOSC10	100	92.742	ENSPVAG00000014780	EXOSC10	100	89.977	Pteropus_vampyrus
ENSG00000171824	EXOSC10	98	61.916	ENSPNYG00000007387	exosc10	97	61.721	Pundamilia_nyererei
ENSG00000171824	EXOSC10	99	59.956	ENSPNAG00000028864	exosc10	98	60.044	Pygocentrus_nattereri
ENSG00000171824	EXOSC10	100	90.323	ENSRNOG00000010719	Exosc10	100	87.133	Rattus_norvegicus
ENSG00000171824	EXOSC10	100	86.512	ENSRBIG00000039772	EXOSC10	100	86.512	Rhinopithecus_bieti
ENSG00000171824	EXOSC10	100	97.581	ENSRROG00000036700	EXOSC10	100	97.558	Rhinopithecus_roxellana
ENSG00000171824	EXOSC10	65	32.373	YOR001W	-	71	32.373	Saccharomyces_cerevisiae
ENSG00000171824	EXOSC10	98	88.773	ENSSBOG00000020768	EXOSC10	100	88.773	Saimiri_boliviensis_boliviensis
ENSG00000171824	EXOSC10	96	78.848	ENSSHAG00000013572	EXOSC10	100	79.201	Sarcophilus_harrisii
ENSG00000171824	EXOSC10	95	60.936	ENSSFOG00015004512	exosc10	97	61.647	Scleropages_formosus
ENSG00000171824	EXOSC10	97	61.661	ENSSMAG00000017318	exosc10	97	61.477	Scophthalmus_maximus
ENSG00000171824	EXOSC10	99	61.192	ENSSDUG00000006646	exosc10	98	60.782	Seriola_dumerili
ENSG00000171824	EXOSC10	99	60.855	ENSSLDG00000025554	exosc10	98	60.559	Seriola_lalandi_dorsalis
ENSG00000171824	EXOSC10	83	65.536	ENSSARG00000013171	EXOSC10	100	65.536	Sorex_araneus
ENSG00000171824	EXOSC10	96	75.725	ENSSPUG00000006844	EXOSC10	96	84.028	Sphenodon_punctatus
ENSG00000171824	EXOSC10	99	61.486	ENSSPAG00000007053	exosc10	98	61.486	Stegastes_partitus
ENSG00000171824	EXOSC10	91	90.037	ENSSSCG00000003412	EXOSC10	100	90.037	Sus_scrofa
ENSG00000171824	EXOSC10	96	70.994	ENSTGUG00000002231	EXOSC10	100	70.994	Taeniopygia_guttata
ENSG00000171824	EXOSC10	98	58.875	ENSTRUG00000012484	exosc10	97	58.875	Takifugu_rubripes
ENSG00000171824	EXOSC10	98	61.194	ENSTNIG00000015181	exosc10	100	59.842	Tetraodon_nigroviridis
ENSG00000171824	EXOSC10	100	90.323	ENSTBEG00000017471	-	73	96.992	Tupaia_belangeri
ENSG00000171824	EXOSC10	100	91.935	ENSTTRG00000001320	EXOSC10	100	89.628	Tursiops_truncatus
ENSG00000171824	EXOSC10	100	94.355	ENSUAMG00000014404	EXOSC10	98	90.235	Ursus_americanus
ENSG00000171824	EXOSC10	99	94.309	ENSUMAG00000023413	EXOSC10	99	88.160	Ursus_maritimus
ENSG00000171824	EXOSC10	70	98.851	ENSVPAG00000004629	EXOSC10	62	96.703	Vicugna_pacos
ENSG00000171824	EXOSC10	91	88.930	ENSVVUG00000027116	EXOSC10	100	88.930	Vulpes_vulpes
ENSG00000171824	EXOSC10	97	61.213	ENSXETG00000006318	exosc10	100	61.213	Xenopus_tropicalis
ENSG00000171824	EXOSC10	97	62.529	ENSXCOG00000004665	exosc10	97	62.100	Xiphophorus_couchianus
ENSG00000171824	EXOSC10	97	62.100	ENSXMAG00000011246	exosc10	97	61.975	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000175	3'-5'-exoribonuclease activity	17412707.23439679.	EXP	Function
GO:0000175	3'-5'-exoribonuclease activity	26950371.	IMP	Function
GO:0000176	nuclear exosome (RNase complex)	26166824.	IDA	Component
GO:0000178	exosome (RNase complex)	20531389.	IDA	Component
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	IEA	Process
GO:0000460	maturation of 5.8S rRNA	17412707.20368444.	IMP	Process
GO:0000956	nuclear-transcribed mRNA catabolic process	17545563.	IMP	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004532	exoribonuclease activity	17174896.	IDA	Function
GO:0005515	protein binding	14731398.15231747.16396833.17234882.17412707.20531386.21255825.23143267.23756462.26496610.	IPI	Function
GO:0005634	nucleus	17545563.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	20531386.	IDA	Component
GO:0005737	cytoplasm	17545563.20531386.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0009048	dosage compensation by inactivation of X chromosome	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0032211	negative regulation of telomere maintenance via telomerase	26950371.	IMP	Process
GO:0035327	transcriptionally active chromatin	20699273.	IMP	Component
GO:0070034	telomerase RNA binding	26950371.	IC	Function
GO:0071028	nuclear mRNA surveillance	17545563.	IMP	Process
GO:0071034	CUT catabolic process	19056938.	IMP	Process
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	16455498.	IMP	Process
GO:0071044	histone mRNA catabolic process	18172165.	IMP	Process
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	20699273.	IMP	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process
GO:1904872	regulation of telomerase RNA localization to Cajal body	26950371.	IMP	Process