EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171865 (Gene tree)
Gene ID: 246243
Gene Symbol: RNASEH1
Alias: N
Full Name: ribonuclease H1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 26,804 bases
Position: chr2:3,531,813-3,558,616
Accession: 18466
RBP type: canonical RBP
Summary: This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000313350	RNase_H	PF00075.24	6.2e-44	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
14506260	Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.	J Biol Chem	2003 Dec 12	Lima WF	-
21191028	Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNA-DNA hybrid molecule at OriLyt.	J Virol	2011 Mar	Rennekamp AJ	doi: 10.1128/JVI.02175-10
9512560	A common 40 amino acid motif in eukaryotic RNases H1 and caulimovirus ORF VI proteins binds to duplex RNAs.	Nucleic Acids Res	1998 Apr 1	Cerritelli SM	-
17663799	Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes.	BMC Evol Biol	2007 Jul 31	Kochiwa H	-
19228196	Ribonuclease H: the enzymes in eukaryotes.	FEBS J	2009 Mar	Cerritelli SM	doi: 10.1111/j.1742-4658.2009.06908.x
23500886	Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid.	J Struct Biol	2013 May	Nguyen TN	doi: 10.1016/j.jsb.2013.02.018
11319219	Investigating the structure of human RNase H1 by site-directed mutagenesis.	J Biol Chem	2001 Jun 29	Wu H	-
18337749	Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.	EMBO J	2008 Apr 9	Nowotny M	doi: 10.1038/emboj.2008.44
25712094	Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages.	Nucleic Acids Res	2015 Mar 11	Liang XH	doi: 10.1093/nar/gkv143
29499955	A Sensitive InVitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides.	Mol Ther Nucleic Acids	2018 Mar 2	Dieckmann A	doi: 10.1016/j.omtn.2017.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000454734	RNASEH1-203	749	-	ENSP00000411646	43 (aa)	-	F8WBP0
ENST00000464986	RNASEH1-204	514	-	-	- (aa)	-	-
ENST00000315212	RNASEH1-201	1887	-	ENSP00000313350	286 (aa)	-	O60930
ENST00000436842	RNASEH1-202	2120	-	ENSP00000404926	43 (aa)	-	F8WD93

Gene Model

Click here to download ENSG00000171865's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03030	DNA replication	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171865's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171865	RNASEH1	89	55.390	ENSAPOG00000000412	rnaseh1	88	56.134	Acanthochromis_polyacanthus
ENSG00000171865	RNASEH1	93	83.521	ENSAMEG00000018433	RNASEH1	100	81.185	Ailuropoda_melanoleuca
ENSG00000171865	RNASEH1	89	55.725	ENSACIG00000014666	rnaseh1	86	56.226	Amphilophus_citrinellus
ENSG00000171865	RNASEH1	89	56.877	ENSAOCG00000015210	rnaseh1	88	57.249	Amphiprion_ocellaris
ENSG00000171865	RNASEH1	89	57.249	ENSAPEG00000014104	rnaseh1	88	57.621	Amphiprion_percula
ENSG00000171865	RNASEH1	89	55.639	ENSATEG00000000598	rnaseh1	93	55.639	Anabas_testudineus
ENSG00000171865	RNASEH1	86	61.240	ENSAPLG00000001961	RNASEH1	100	61.240	Anas_platyrhynchos
ENSG00000171865	RNASEH1	98	51.084	ENSACAG00000016857	rnaseh1	100	51.084	Anolis_carolinensis
ENSG00000171865	RNASEH1	100	92.657	ENSANAG00000024055	RNASEH1	100	92.657	Aotus_nancymaae
ENSG00000171865	RNASEH1	89	54.815	ENSACLG00000006741	rnaseh1	87	55.185	Astatotilapia_calliptera
ENSG00000171865	RNASEH1	91	50.579	ENSAMXG00000042940	rnaseh1	97	50.562	Astyanax_mexicanus
ENSG00000171865	RNASEH1	100	78.322	ENSBTAG00000016235	RNASEH1	100	78.322	Bos_taurus
ENSG00000171865	RNASEH1	89	40.684	WBGene00004382	rnh-1.0	95	40.684	Caenorhabditis_elegans
ENSG00000171865	RNASEH1	100	91.379	ENSCJAG00000035450	RNASEH1	100	91.379	Callithrix_jacchus
ENSG00000171865	RNASEH1	100	81.882	ENSCAFG00000003259	RNASEH1	100	81.882	Canis_familiaris
ENSG00000171865	RNASEH1	54	92.857	ENSCAFG00020004994	RNASEH1	99	92.857	Canis_lupus_dingo
ENSG00000171865	RNASEH1	83	66.387	ENSCHIG00000022230	-	100	66.387	Capra_hircus
ENSG00000171865	RNASEH1	100	77.352	ENSCHIG00000022264	-	100	77.352	Capra_hircus
ENSG00000171865	RNASEH1	100	82.168	ENSTSYG00000012926	RNASEH1	99	82.168	Carlito_syrichta
ENSG00000171865	RNASEH1	85	81.893	ENSCAPG00000004813	RNASEH1	99	81.893	Cavia_aperea
ENSG00000171865	RNASEH1	100	77.320	ENSCPOG00000022278	Rnaseh1	97	77.320	Cavia_porcellus
ENSG00000171865	RNASEH1	100	90.690	ENSCCAG00000038017	RNASEH1	100	90.690	Cebus_capucinus
ENSG00000171865	RNASEH1	100	83.217	ENSCATG00000016818	-	100	83.217	Cercocebus_atys
ENSG00000171865	RNASEH1	100	94.056	ENSCATG00000016515	-	100	94.056	Cercocebus_atys
ENSG00000171865	RNASEH1	100	79.791	ENSCLAG00000002440	RNASEH1	100	79.791	Chinchilla_lanigera
ENSG00000171865	RNASEH1	100	92.657	ENSCSAG00000006943	RNASEH1	100	92.657	Chlorocebus_sabaeus
ENSG00000171865	RNASEH1	69	82.741	ENSCHOG00000008547	RNASEH1	97	82.741	Choloepus_hoffmanni
ENSG00000171865	RNASEH1	91	61.091	ENSCPBG00000021620	RNASEH1	98	61.481	Chrysemys_picta_bellii
ENSG00000171865	RNASEH1	89	39.273	ENSCING00000014054	-	91	39.273	Ciona_intestinalis
ENSG00000171865	RNASEH1	76	38.565	ENSCSAVG00000000009	-	96	38.565	Ciona_savignyi
ENSG00000171865	RNASEH1	100	93.357	ENSCANG00000037763	RNASEH1	100	93.357	Colobus_angolensis_palliatus
ENSG00000171865	RNASEH1	100	74.825	ENSCGRG00001008950	Rnaseh1	100	76.224	Cricetulus_griseus_chok1gshd
ENSG00000171865	RNASEH1	100	74.825	ENSCGRG00000006029	Rnaseh1	100	76.224	Cricetulus_griseus_crigri
ENSG00000171865	RNASEH1	90	53.053	ENSCSEG00000005741	rnaseh1	93	52.239	Cynoglossus_semilaevis
ENSG00000171865	RNASEH1	89	55.682	ENSCVAG00000018717	rnaseh1	87	55.682	Cyprinodon_variegatus
ENSG00000171865	RNASEH1	89	52.941	ENSDARG00000042571	rnaseh1	96	52.941	Danio_rerio
ENSG00000171865	RNASEH1	100	78.746	ENSDNOG00000016056	RNASEH1	100	78.746	Dasypus_novemcinctus
ENSG00000171865	RNASEH1	100	80.070	ENSDORG00000000704	Rnaseh1	100	80.070	Dipodomys_ordii
ENSG00000171865	RNASEH1	92	36.120	FBgn0023171	rnh1	95	36.120	Drosophila_melanogaster
ENSG00000171865	RNASEH1	100	74.913	ENSETEG00000012674	RNASEH1	100	74.913	Echinops_telfairi
ENSG00000171865	RNASEH1	89	45.211	ENSEBUG00000006116	rnaseh1	77	45.211	Eptatretus_burgeri
ENSG00000171865	RNASEH1	90	47.059	ENSEBUG00000008898	rnaseh1	98	47.059	Eptatretus_burgeri
ENSG00000171865	RNASEH1	100	82.578	ENSEASG00005022200	RNASEH1	98	82.578	Equus_asinus_asinus
ENSG00000171865	RNASEH1	100	82.578	ENSECAG00000020695	RNASEH1	98	82.578	Equus_caballus
ENSG00000171865	RNASEH1	89	55.109	ENSELUG00000010112	rnaseh1	90	55.109	Esox_lucius
ENSG00000171865	RNASEH1	100	82.230	ENSFCAG00000025832	RNASEH1	100	82.230	Felis_catus
ENSG00000171865	RNASEH1	91	59.075	ENSFALG00000002069	RNASEH1	94	59.075	Ficedula_albicollis
ENSG00000171865	RNASEH1	100	76.573	ENSFDAG00000002035	RNASEH1	88	76.573	Fukomys_damarensis
ENSG00000171865	RNASEH1	89	55.133	ENSGMOG00000013818	rnaseh1	88	55.133	Gadus_morhua
ENSG00000171865	RNASEH1	95	59.722	ENSGALG00000016389	RNASEH1	97	59.722	Gallus_gallus
ENSG00000171865	RNASEH1	90	54.682	ENSGAFG00000001776	rnaseh1	90	54.682	Gambusia_affinis
ENSG00000171865	RNASEH1	89	56.226	ENSGACG00000011935	rnaseh1	88	56.226	Gasterosteus_aculeatus
ENSG00000171865	RNASEH1	90	59.854	ENSGAGG00000009150	RNASEH1	62	60.584	Gopherus_agassizii
ENSG00000171865	RNASEH1	100	97.552	ENSGGOG00000034822	RNASEH1	100	97.552	Gorilla_gorilla
ENSG00000171865	RNASEH1	89	54.815	ENSHBUG00000004666	rnaseh1	87	55.556	Haplochromis_burtoni
ENSG00000171865	RNASEH1	98	76.786	ENSHGLG00000002585	Rnaseh1	90	76.786	Heterocephalus_glaber_female
ENSG00000171865	RNASEH1	98	76.786	ENSHGLG00100005105	Rnaseh1	90	76.786	Heterocephalus_glaber_male
ENSG00000171865	RNASEH1	91	52.768	ENSHCOG00000012329	rnaseh1	89	52.768	Hippocampus_comes
ENSG00000171865	RNASEH1	91	56.371	ENSIPUG00000023060	rnaseh1	97	56.371	Ictalurus_punctatus
ENSG00000171865	RNASEH1	98	80.000	ENSSTOG00000012774	RNASEH1	99	80.000	Ictidomys_tridecemlineatus
ENSG00000171865	RNASEH1	100	69.767	ENSJJAG00000020238	Rnaseh1	100	79.070	Jaculus_jaculus
ENSG00000171865	RNASEH1	100	66.084	ENSJJAG00000008994	-	100	66.084	Jaculus_jaculus
ENSG00000171865	RNASEH1	100	73.427	ENSJJAG00000021481	-	100	73.427	Jaculus_jaculus
ENSG00000171865	RNASEH1	90	54.717	ENSKMAG00000001373	rnaseh1	88	54.717	Kryptolebias_marmoratus
ENSG00000171865	RNASEH1	91	53.430	ENSLBEG00000004480	rnaseh1	97	53.791	Labrus_bergylta
ENSG00000171865	RNASEH1	92	53.357	ENSLACG00000007100	RNASEH1	90	54.286	Latimeria_chalumnae
ENSG00000171865	RNASEH1	89	57.721	ENSLOCG00000017212	rnaseh1	96	56.929	Lepisosteus_oculatus
ENSG00000171865	RNASEH1	99	80.769	ENSLAFG00000015091	RNASEH1	99	80.769	Loxodonta_africana
ENSG00000171865	RNASEH1	100	82.168	ENSMFAG00000002323	-	100	82.168	Macaca_fascicularis
ENSG00000171865	RNASEH1	100	93.706	ENSMFAG00000000063	-	100	93.706	Macaca_fascicularis
ENSG00000171865	RNASEH1	100	82.168	ENSMMUG00000019280	-	100	82.168	Macaca_mulatta
ENSG00000171865	RNASEH1	100	93.357	ENSMNEG00000040183	-	100	93.357	Macaca_nemestrina
ENSG00000171865	RNASEH1	100	82.867	ENSMNEG00000029676	-	100	82.867	Macaca_nemestrina
ENSG00000171865	RNASEH1	85	95.062	ENSMLEG00000039352	-	100	95.062	Mandrillus_leucophaeus
ENSG00000171865	RNASEH1	100	84.965	ENSMLEG00000028662	-	100	84.965	Mandrillus_leucophaeus
ENSG00000171865	RNASEH1	90	58.364	ENSMAMG00000019725	rnaseh1	94	58.364	Mastacembelus_armatus
ENSG00000171865	RNASEH1	89	54.815	ENSMZEG00005013006	rnaseh1	87	55.185	Maylandia_zebra
ENSG00000171865	RNASEH1	80	60.324	ENSMGAG00000013979	RNASEH1	99	60.324	Meleagris_gallopavo
ENSG00000171865	RNASEH1	99	76.491	ENSMAUG00000014957	Rnaseh1	99	76.491	Mesocricetus_auratus
ENSG00000171865	RNASEH1	100	85.315	ENSMICG00000033156	RNASEH1	99	85.315	Microcebus_murinus
ENSG00000171865	RNASEH1	100	76.817	ENSMOCG00000015522	Rnaseh1	100	76.817	Microtus_ochrogaster
ENSG00000171865	RNASEH1	89	53.759	ENSMMOG00000015902	rnaseh1	87	53.759	Mola_mola
ENSG00000171865	RNASEH1	96	71.223	ENSMODG00000014491	-	96	71.223	Monodelphis_domestica
ENSG00000171865	RNASEH1	80	63.755	ENSMODG00000028814	-	92	64.783	Monodelphis_domestica
ENSG00000171865	RNASEH1	90	55.224	ENSMALG00000010565	rnaseh1	88	55.224	Monopterus_albus
ENSG00000171865	RNASEH1	100	77.972	MGP_CAROLIEiJ_G0017660	Rnaseh1	100	77.972	Mus_caroli
ENSG00000171865	RNASEH1	100	77.972	ENSMUSG00000020630	Rnaseh1	100	77.972	Mus_musculus
ENSG00000171865	RNASEH1	99	77.193	MGP_PahariEiJ_G0029418	Rnaseh1	99	77.895	Mus_pahari
ENSG00000171865	RNASEH1	100	78.322	MGP_SPRETEiJ_G0018502	Rnaseh1	100	78.322	Mus_spretus
ENSG00000171865	RNASEH1	72	82.439	ENSMPUG00000012984	RNASEH1	99	82.439	Mustela_putorius_furo
ENSG00000171865	RNASEH1	98	78.292	ENSNGAG00000015966	Rnaseh1	92	78.292	Nannospalax_galili
ENSG00000171865	RNASEH1	89	55.185	ENSNBRG00000008739	rnaseh1	87	55.556	Neolamprologus_brichardi
ENSG00000171865	RNASEH1	100	95.349	ENSNLEG00000015400	RNASEH1	100	82.292	Nomascus_leucogenys
ENSG00000171865	RNASEH1	91	85.115	ENSNLEG00000000059	-	98	85.115	Nomascus_leucogenys
ENSG00000171865	RNASEH1	91	48.846	ENSMEUG00000003610	-	91	48.846	Notamacropus_eugenii
ENSG00000171865	RNASEH1	100	73.010	ENSOPRG00000005072	RNASEH1	99	73.010	Ochotona_princeps
ENSG00000171865	RNASEH1	100	77.972	ENSODEG00000000235	Rnaseh1	97	77.972	Octodon_degus
ENSG00000171865	RNASEH1	89	55.185	ENSONIG00000018697	rnaseh1	96	55.185	Oreochromis_niloticus
ENSG00000171865	RNASEH1	100	81.818	ENSOCUG00000006117	RNASEH1	100	81.818	Oryctolagus_cuniculus
ENSG00000171865	RNASEH1	89	55.762	ENSORLG00000018127	rnaseh1	94	55.762	Oryzias_latipes
ENSG00000171865	RNASEH1	89	55.762	ENSORLG00020013660	rnaseh1	87	55.762	Oryzias_latipes_hni
ENSG00000171865	RNASEH1	89	55.639	ENSORLG00015011338	rnaseh1	87	55.639	Oryzias_latipes_hsok
ENSG00000171865	RNASEH1	81	54.321	ENSOMEG00000004710	rnaseh1	90	54.321	Oryzias_melastigma
ENSG00000171865	RNASEH1	100	82.927	ENSOGAG00000017176	RNASEH1	100	82.927	Otolemur_garnettii
ENSG00000171865	RNASEH1	100	67.466	ENSOARG00000005386	RNASEH1	100	67.466	Ovis_aries
ENSG00000171865	RNASEH1	100	99.650	ENSPPAG00000034221	RNASEH1	100	99.650	Pan_paniscus
ENSG00000171865	RNASEH1	100	82.230	ENSPPRG00000015513	RNASEH1	100	82.230	Panthera_pardus
ENSG00000171865	RNASEH1	85	85.185	ENSPTIG00000019034	RNASEH1	85	85.185	Panthera_tigris_altaica
ENSG00000171865	RNASEH1	100	99.650	ENSPTRG00000011614	RNASEH1	100	99.650	Pan_troglodytes
ENSG00000171865	RNASEH1	88	87.938	ENSPTRG00000043403	-	97	87.938	Pan_troglodytes
ENSG00000171865	RNASEH1	100	93.357	ENSPANG00000000443	RNASEH1	100	93.357	Papio_anubis
ENSG00000171865	RNASEH1	100	81.395	ENSPANG00000018246	-	100	79.720	Papio_anubis
ENSG00000171865	RNASEH1	90	50.192	ENSPKIG00000003146	rnaseh1	97	50.575	Paramormyrops_kingsleyae
ENSG00000171865	RNASEH1	95	58.763	ENSPSIG00000002937	RNASEH1	98	61.049	Pelodiscus_sinensis
ENSG00000171865	RNASEH1	89	52.510	ENSPMGG00000017463	rnaseh1	90	52.510	Periophthalmus_magnuspinnatus
ENSG00000171865	RNASEH1	100	77.352	ENSPEMG00000022465	-	100	77.700	Peromyscus_maniculatus_bairdii
ENSG00000171865	RNASEH1	51	43.624	ENSPCIG00000026047	-	84	43.624	Phascolarctos_cinereus
ENSG00000171865	RNASEH1	91	68.582	ENSPCIG00000023334	-	90	68.582	Phascolarctos_cinereus
ENSG00000171865	RNASEH1	90	56.343	ENSPFOG00000002841	rnaseh1	90	56.343	Poecilia_formosa
ENSG00000171865	RNASEH1	70	50.244	ENSPLAG00000021349	-	80	50.244	Poecilia_latipinna
ENSG00000171865	RNASEH1	90	55.970	ENSPMEG00000016826	rnaseh1	90	55.970	Poecilia_mexicana
ENSG00000171865	RNASEH1	90	55.515	ENSPREG00000012197	rnaseh1	90	55.515	Poecilia_reticulata
ENSG00000171865	RNASEH1	100	90.698	ENSPPYG00000008067	-	100	91.188	Pongo_abelii
ENSG00000171865	RNASEH1	100	93.023	ENSPPYG00000025873	RNASEH1	100	85.315	Pongo_abelii
ENSG00000171865	RNASEH1	99	75.704	ENSPCAG00000002500	RNASEH1	99	75.704	Procavia_capensis
ENSG00000171865	RNASEH1	100	77.622	ENSPCOG00000019444	RNASEH1	99	77.622	Propithecus_coquereli
ENSG00000171865	RNASEH1	99	75.439	ENSPVAG00000002070	RNASEH1	99	75.439	Pteropus_vampyrus
ENSG00000171865	RNASEH1	89	54.104	ENSPNYG00000001292	rnaseh1	87	54.478	Pundamilia_nyererei
ENSG00000171865	RNASEH1	97	55.319	ENSPNAG00000022344	rnaseh1	96	55.319	Pygocentrus_nattereri
ENSG00000171865	RNASEH1	99	76.140	ENSRNOG00000008584	Rnaseh1	99	77.544	Rattus_norvegicus
ENSG00000171865	RNASEH1	100	92.657	ENSRBIG00000034222	RNASEH1	99	92.657	Rhinopithecus_bieti
ENSG00000171865	RNASEH1	100	93.007	ENSRROG00000041761	RNASEH1	99	93.007	Rhinopithecus_roxellana
ENSG00000171865	RNASEH1	90	52.174	YMR234W	-	82	52.174	Saccharomyces_cerevisiae
ENSG00000171865	RNASEH1	100	90.345	ENSSBOG00000025411	RNASEH1	100	90.345	Saimiri_boliviensis_boliviensis
ENSG00000171865	RNASEH1	92	71.374	ENSSHAG00000013051	RNASEH1	89	71.374	Sarcophilus_harrisii
ENSG00000171865	RNASEH1	97	51.178	ENSSFOG00015002709	rnaseh1	98	51.178	Scleropages_formosus
ENSG00000171865	RNASEH1	89	56.981	ENSSMAG00000007586	rnaseh1	87	57.358	Scophthalmus_maximus
ENSG00000171865	RNASEH1	89	53.480	ENSSDUG00000008217	rnaseh1	93	54.511	Seriola_dumerili
ENSG00000171865	RNASEH1	87	53.585	ENSSLDG00000000442	rnaseh1	93	56.225	Seriola_lalandi_dorsalis
ENSG00000171865	RNASEH1	92	58.333	ENSSPUG00000006644	RNASEH1	94	58.333	Sphenodon_punctatus
ENSG00000171865	RNASEH1	89	56.439	ENSSPAG00000009353	rnaseh1	87	57.197	Stegastes_partitus
ENSG00000171865	RNASEH1	92	81.439	ENSSSCG00000025305	RNASEH1	99	78.521	Sus_scrofa
ENSG00000171865	RNASEH1	99	54.934	ENSTGUG00000012980	RNASEH1	99	54.575	Taeniopygia_guttata
ENSG00000171865	RNASEH1	98	51.701	ENSTRUG00000015774	rnaseh1	96	53.676	Takifugu_rubripes
ENSG00000171865	RNASEH1	91	57.519	ENSTNIG00000010715	rnaseh1	96	57.519	Tetraodon_nigroviridis
ENSG00000171865	RNASEH1	100	77.352	ENSTTRG00000001615	RNASEH1	100	77.352	Tursiops_truncatus
ENSG00000171865	RNASEH1	56	91.195	ENSUAMG00000018254	RNASEH1	82	91.195	Ursus_americanus
ENSG00000171865	RNASEH1	69	78.173	ENSUMAG00000003941	RNASEH1	65	78.173	Ursus_maritimus
ENSG00000171865	RNASEH1	100	67.247	ENSVPAG00000011589	RNASEH1	100	67.247	Vicugna_pacos
ENSG00000171865	RNASEH1	100	82.927	ENSVVUG00000008633	RNASEH1	90	82.927	Vulpes_vulpes
ENSG00000171865	RNASEH1	90	55.056	ENSXETG00000001212	rnaseh1	91	55.056	Xenopus_tropicalis
ENSG00000171865	RNASEH1	90	44.747	ENSXETG00000030371	-	100	44.747	Xenopus_tropicalis
ENSG00000171865	RNASEH1	90	53.558	ENSXMAG00000002357	rnaseh1	90	53.558	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000287	magnesium ion binding	-	IEA	Function
GO:0003676	nucleic acid binding	9799596.	TAS	Function
GO:0003723	RNA binding	9799596.	TAS	Function
GO:0004523	RNA-DNA hybrid ribonuclease activity	21873635.	IBA	Function
GO:0004523	RNA-DNA hybrid ribonuclease activity	21700224.	IDA	Function
GO:0004540	ribonuclease activity	9799596.	TAS	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0006401	RNA catabolic process	9799596.	TAS	Process
GO:0043137	DNA replication, removal of RNA primer	21873635.	IBA	Process
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	21873635.	IBA	Process