EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000171914 (Gene tree)
Gene ID: 83660
Gene Symbol: TLN2
Alias: KIAA0320|ILWEQ
Full Name: talin 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 454,106 bases
Position: chr15:62,390,526-62,844,631
Accession: 15447
RBP type: non-canonical RBP
Summary: This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000561197	TLN2-208	306	-	-	- (aa)	-	-
ENST00000467297	TLN2-201	509	-	-	- (aa)	-	-
ENST00000474847	TLN2-203	1013	-	-	- (aa)	-	-
ENST00000489129	TLN2-204	6420	-	-	- (aa)	-	-
ENST00000559908	TLN2-207	717	-	-	- (aa)	-	-
ENST00000561311	TLN2-209	11880	XM_005254708	ENSP00000453508	2542 (aa)	XP_005254765	Q9Y4G6
ENST00000472902	TLN2-202	2116	-	ENSP00000453812	330 (aa)	-	H0YN01
ENST00000561322	TLN2-210	249	-	-	- (aa)	-	-
ENST00000636159	TLN2-211	7441	-	ENSP00000490662	1567 (aa)	-	A0A1B0GVU7
ENST00000494733	TLN2-205	5155	-	ENSP00000453730	1471 (aa)	-	H0YMT1
ENST00000559174	TLN2-206	573	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000171914's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04015	Rap1 signaling pathway	KEGG
hsa04510	Focal adhesion	KEGG
hsa04611	Platelet activation	KEGG
hsa05166	Human T-cell leukemia virus 1 infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000171914	Cholesterol, LDL	1.10507394681395E-7	17903299
ENSG00000171914	Echocardiography	6.89152682301061E-5	17903301
ENSG00000171914	Echocardiography	5.60146183385957E-5	17903301
ENSG00000171914	Echocardiography	2.47573975168072E-5	17903301
ENSG00000171914	Echocardiography	2.25519769337518E-5	17903301
ENSG00000171914	Stroke	7.4424126E-005	19369658
ENSG00000171914	Alcoholism	2.26E-05	-
ENSG00000171914	Alcoholism	3.67E-05	-
ENSG00000171914	Respiratory Function Tests	2.4690000E-006	-
ENSG00000171914	Respiratory Function Tests	1.6220000E-006	20010835
ENSG00000171914	Alzheimer Disease	3E-7	20197096
ENSG00000171914	Sleep	7E-6	23728906

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000171914	rs812957	15	62508256	G	High light scatter reticulocyte percentage of red cells	27863252	[0.031-0.047] unit increase	0.0391755	EFO_0007986
ENSG00000171914	rs35997243	15	62800701	C	High light scatter reticulocyte percentage of red cells	27863252	[0.088-0.146] unit increase	0.1170721	EFO_0007986
ENSG00000171914	rs780142	15	62505765	G	Reticulocyte count	27863252	[0.022-0.038] unit increase	0.03026128	EFO_0007986
ENSG00000171914	rs2456930	15	62395140	G	Brain structure (temporal lobe volume)	20197096	[NR] unit increase	3843.9	EFO_0000249
ENSG00000171914	rs12913538	15	62606961	A	Sleep depth	23728906	[0.061-0.139] unit increase	0.1	EFO_0005273
ENSG00000171914	rs10775181	15	62722349	?	Yeast infection	28928442	[0.046-0.114] unit increase	0.0801	EFO_0008412
ENSG00000171914	rs956006	15	62516340	T	Pulse pressure	28135244	[0.11-0.25] unit decrease	0.1789	EFO_0005763
ENSG00000171914	rs67476890	15	62499295	C	beta-nerve growth factor levels	27989323	[0.1-0.25] SD units decrease	0.1769	EFO_0008035
ENSG00000171914	rs780142	15	62505765	G	Reticulocyte fraction of red cells	27863252	[0.024-0.04] unit increase	0.03215649	EFO_0007986
ENSG00000171914	rs59191668	15	62560754	G	Immature fraction of reticulocytes	27863252	[0.031-0.045] unit increase	0.03793851	EFO_0007986
ENSG00000171914	rs8041447	15	62787344	A	Immature fraction of reticulocytes	27863252	[0.016-0.031] unit increase	0.02374927	EFO_0007986
ENSG00000171914	rs35997243	15	62800701	C	Immature fraction of reticulocytes	27863252	[0.11-0.16] unit increase	0.1347317	EFO_0007986
ENSG00000171914	rs812957	15	62508256	G	High light scatter reticulocyte count	27863252	[0.03-0.046] unit increase	0.03818624	EFO_0007986
ENSG00000171914	rs35997243	15	62800701	C	High light scatter reticulocyte count	27863252	[0.088-0.147] unit increase	0.1173148	EFO_0007986
ENSG00000171914	rs56259139	15	62455571	?	Heel bone mineral density	30048462	[0.016-0.03] unit increase	0.0229977	EFO_0009270
ENSG00000171914	rs2471032	15	62412942	C	Heel bone mineral density	30598549	[0.012-0.022] unit decrease	0.0170094	EFO_0009270
ENSG00000171914	rs56259139	15	62455571	C	Heel bone mineral density	30598549	[0.014-0.027] unit increase	0.0206876	EFO_0009270
ENSG00000171914	rs990526	15	62538505	?	White blood cell count	30595370			EFO_0004308
ENSG00000171914	rs58646822	15	62513935	T	Pulse pressure	30578418	[0.18-0.3] mmHg decrease	0.2414	EFO_0005763
ENSG00000171914	rs956006	15	62516340	T	Diastolic blood pressure	30578418	[0.1-0.22] mmHg increase	0.1595	EFO_0006336
ENSG00000171914	rs956006	15	62516340	C	Pulse pressure	27841878	unit increase	0.215	EFO_0005763
ENSG00000171914	rs956006	15	62516340	C	Pulse pressure	27841878	unit increase	0.203	EFO_0005763
ENSG00000171914	rs956006	15	62516340	C	Pulse pressure	27841878	unit increase	0.207	EFO_0005763
ENSG00000171914	rs2471032	15	62412942	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171914's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001726	ruffle	-	IEA	Component
GO:0003779	actin binding	10320934.	NAS	Function
GO:0005198	structural molecule activity	10320934.	NAS	Function
GO:0005200	structural constituent of cytoskeleton	-	IEA	Function
GO:0005515	protein binding	10320934.19234221.	IPI	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0007016	cytoskeletal anchoring at plasma membrane	-	IEA	Process
GO:0007043	cell-cell junction assembly	15494027.	TAS	Process
GO:0007155	cell adhesion	11907066.	NAS	Process
GO:0015629	actin cytoskeleton	10320934.	NAS	Component
GO:0045202	synapse	11907066.	NAS	Component
GO:0051015	actin filament binding	-	IEA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27694340	Talin2-mediated traction force drives matrix degradation and cell invasion.	J Cell Sci	2016 Oct 1	Qi L	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr15	62762365	Missense_Mutation	novel	N1625Y	0.37
ACC	chr15	62805739	Missense_Mutation	novel	A2206V	0.51
ACC	chr15	62725032	Silent	NA	T1061T	0.16
ACC	chr15	62725059	Missense_Mutation	novel	K1070N	0.33
ACC	chr15	62739545	Missense_Mutation	novel	Q1295H	0.48
ACC	chr15	62771055	In_Frame_Del	novel	L1764_L1775del	0.9
BLCA	chr15	62702853	Missense_Mutation	novel	E665K	0.44
BLCA	chr15	62740548	Intron	novel		0.21
BLCA	chr15	62740644	Missense_Mutation	NA	Q1300H	0.15
BLCA	chr15	62701200	Missense_Mutation	NA	V561G	0.1
BLCA	chr15	62692885	Missense_Mutation	NA	E387K	0.27
BLCA	chr15	62776841	Silent	rs146956888	L1815L	0.19
BLCA	chr15	62833539	Silent	NA	I2346I	0.44
BLCA	chr15	62763633	Missense_Mutation	novel	E1678K	0.4
BLCA	chr15	62647428	Missense_Mutation	novel	E40K	0.19
BLCA	chr15	62737027	Missense_Mutation	NA	E1170Q	0.22
BLCA	chr15	62836004	Silent	NA	S2435S	0.33
BLCA	chr15	62738329	Missense_Mutation	novel	D1228G	0.22
BLCA	chr15	62652038	Missense_Mutation	NA	Q90E	0.21
BLCA	chr15	62833347	Intron	novel		0.41
BLCA	chr15	62838966	Silent	rs200809264	V2495V	0.16
BLCA	chr15	62717629	Silent	novel	Q939Q	0.56
BLCA	chr15	62805746	Silent	novel	L2208L	0.28
BLCA	chr15	62717611	Silent	novel	Q933Q	0.25
BLCA	chr15	62647341	Missense_Mutation	rs771261514	R11C	0.24
BLCA	chr15	62833696	Intron	novel		0.32
BLCA	chr15	62833605	Missense_Mutation	novel	Q2368H	0.3
BLCA	chr15	62736948	Silent	rs751572891	S1143S	0.24
BLCA	chr15	62835956	Silent	rs369147646	H2419H	0.24
BLCA	chr15	62776761	Splice_Region	novel		0.32
BLCA	chr15	62716375	Silent	NA	L893L	0.43
BLCA	chr15	62805718	Missense_Mutation	novel	Q2199R	0.25
BLCA	chr15	62800707	Missense_Mutation	novel	E2139K	0.26
BLCA	chr15	62722427	Silent	novel	L1022L	0.32
BRCA	chr15	62698800	Missense_Mutation	rs764083207	H507R	0.55
BRCA	chr15	62755608	Missense_Mutation	rs779849306	T1518M	0.62
BRCA	chr15	62766322	Missense_Mutation	NA	A1699V	0.13
BRCA	chr15	62656052	Missense_Mutation	NA	R209K	0.5
BRCA	chr15	62736922	Nonsense_Mutation	NA	Q1135*	0.71
BRCA	chr15	62753939	Intron	novel		0.26
BRCA	chr15	62653311	Missense_Mutation	novel	D172N	0.09
BRCA	chr15	62761756	Missense_Mutation	NA	E1572K	0.3
BRCA	chr15	62653188	Missense_Mutation	novel	L131V	0.17
BRCA	chr15	62737003	Missense_Mutation	novel	E1162K	0.09
BRCA	chr15	62753979	Intron	novel		0.18
BRCA	chr15	62805601	Missense_Mutation	NA	V2160G	0.14
BRCA	chr15	62840652	3'UTR	novel		0.31
BRCA	chr15	62836061	Missense_Mutation	NA	M2454I	0.4
BRCA	chr15	62809981	Silent	NA	F2240F	0.15
BRCA	chr15	62739445	Missense_Mutation	NA	T1262I	0.27
BRCA	chr15	62783870	Missense_Mutation	novel	A1906T	0.11
BRCA	chr15	62835904	Missense_Mutation	novel	A2402G	0.07
BRCA	chr15	62697849	Missense_Mutation	rs754986736	R485Q	0.43
CESC	chr15	62686710	Missense_Mutation	novel	V343M	0.39
CESC	chr15	62694387	Frame_Shift_Del	novel	*K431Sfs25**	0.49
CESC	chr15	62762356	Missense_Mutation	novel	L1622V	0.21
CESC	chr15	62797216	Splice_Region	novel		0.47
CESC	chr15	62647341	Missense_Mutation	rs771261514	R11C	0.33
CESC	chr15	62840620	3'UTR	novel		0.38
CESC	chr15	62819542	Missense_Mutation	rs764058761	F2266L	0.58
CESC	chr15	62833314	Intron	novel		0.33
CESC	chr15	62650087	Missense_Mutation	novel	S47C	0.13
CESC	chr15	62702056	Silent	novel	L587L	0.17
CESC	chr15	62673863	Silent	NA	Q275Q	0.33
CHOL	chr15	62655982	Frame_Shift_Del	novel	*G186Efs2**	0.18
COAD	chr15	62835897	Missense_Mutation	novel	M2400V	0.07
COAD	chr15	62783794	Silent	rs367781225	P1880P	0.43
COAD	chr15	62835774	Missense_Mutation	novel	Q2389L	0.09
COAD	chr15	62736948	Silent	rs751572891	S1143S	0.24
COAD	chr15	62770983	Missense_Mutation	novel	Y1739S	0.28
COAD	chr15	62824024	Intron	novel		0.27
COAD	chr15	62650121	Silent	rs759137070	P58P	0.33
COAD	chr15	62748441	Silent	NA	L1372L	0.34
COAD	chr15	62712022	Missense_Mutation	novel	L860R	0.24
COAD	chr15	62692884	Silent	novel	T386T	0.1
COAD	chr15	62707234	Missense_Mutation	novel	Q718P	0.19
COAD	chr15	62748434	Missense_Mutation	NA	R1370Q	0.31
COAD	chr15	62736896	Missense_Mutation	rs535939717	T1126M	0.32
COAD	chr15	62686755	Missense_Mutation	novel	T358A	0.2
COAD	chr15	62716452	Missense_Mutation	rs375098264	R919Q	0.37
COAD	chr15	62739448	Frame_Shift_Del	NA	*G1264Afs40**	0.38
COAD	chr15	62692885	Missense_Mutation	NA	E387K	0.13
COAD	chr15	62761680	Splice_Site	novel	X1547_splice	0.11
COAD	chr15	62833393	Intron	novel		0.29
COAD	chr15	62797285	Silent	rs772151916	A2039A	0.26
COAD	chr15	62655996	Silent	rs777133814	N190N	0.33
COAD	chr15	62840699	3'UTR	novel		0.1
COAD	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.19
COAD	chr15	62800405	Missense_Mutation	rs748536008	A2091V	0.13
COAD	chr15	62838897	Silent	NA	V2472V	0.34
COAD	chr15	62739455	Silent	NA	Q1265Q	0.3
COAD	chr15	62809981	Silent	NA	F2240F	0.4
COAD	chr15	62800675	Missense_Mutation	novel	S2128L	0.34
COAD	chr15	62776883	Silent	novel	V1829V	0.21
COAD	chr15	62736893	Missense_Mutation	NA	E1125A	0.28
COAD	chr15	62762305	Missense_Mutation	NA	A1605S	0.16
COAD	chr15	62833394	Intron	novel		0.34
COAD	chr15	62805600	Missense_Mutation	NA	V2160M	0.5
DLBC	chr15	62698798	Missense_Mutation	novel	M506I	0.21
DLBC	chr15	62835905	Silent	rs74020685	A2402A	0.38
DLBC	chr15	62725022	Missense_Mutation	rs767177524	T1058M	0.84
ESCA	chr15	62840989	3'UTR	rs548516251		0.22
ESCA	chr15	62711931	Missense_Mutation	rs568266946	R830W	0.25
ESCA	chr15	62712078	Splice_Site	novel	X878_splice	0.3
ESCA	chr15	62800488	Missense_Mutation	novel	A2119S	0.15
ESCA	chr15	62823987	Intron	rs777464613		0.32
ESCA	chr15	62796283	Missense_Mutation	novel	A2014T	0.11
ESCA	chr15	62841243	3'UTR	novel		0.14
ESCA	chr15	62771022	Missense_Mutation	novel	S1752Y	0.15
ESCA	chr15	62755381	Intron	novel		0.21
ESCA	chr15	62653286	Missense_Mutation	novel	L163F	0.19
ESCA	chr15	62796205	Missense_Mutation	novel	G1988R	0.09
ESCA	chr15	62750449	Silent	novel	L1389L	0.16
ESCA	chr15	62762342	Missense_Mutation	rs776245129	R1617H	0.31
ESCA	chr15	62841271	3'UTR	novel		0.48
ESCA	chr15	62819621	Nonsense_Mutation	novel	G2293*	0.2
GBM	chr15	62771122	Silent	NA	G1785G	0.45
GBM	chr15	62838914	Missense_Mutation	novel	A2478V	0.28
GBM	chr15	62835766	Silent	rs139730009	D2386D	0.31
GBM	chr15	62707176	Missense_Mutation	novel	T699S	0.08
GBM	chr15	62640325	Intron	novel		0.43
GBM	chr15	62763567	Missense_Mutation	NA	K1656Q	0.2
GBM	chr15	62766361	Missense_Mutation	NA	G1712E	0.29
GBM	chr15	62650096	Missense_Mutation	novel	G50E	0.41
GBM	chr15	62754040	Intron	novel		0.44
GBM	chr15	62766371	Silent	rs201384963	I1715I	0.4
GBM	chr15	62655993	Missense_Mutation	novel	E189D	0.35
GBM	chr15	62792731	Missense_Mutation	novel	T1943P	0.33
GBM	chr15	62702769	Nonsense_Mutation	novel	R637*	0.12
GBM	chr15	62783781	Missense_Mutation	novel	S1876L	0.44
GBM	chr15	62640315	Intron	novel		0.11
GBM	chr15	62819602	Missense_Mutation	NA	Q2286H	0.38
HNSC	chr15	62647405	Missense_Mutation	rs554667095	R32Q	0.08
HNSC	chr15	62724996	Silent	novel	P1049P	0.38
HNSC	chr15	62833575	Silent	rs758459760	S2358S	0.2
HNSC	chr15	62686641	Missense_Mutation	novel	E320K	0.44
HNSC	chr15	62776796	Silent	rs145072613	A1800A	0.21
HNSC	chr15	62697797	Missense_Mutation	novel	V468I	0.42
HNSC	chr15	62835948	Missense_Mutation	rs140723056	Q2417E	0.1
HNSC	chr15	62647394	Nonsense_Mutation	novel	Y28*	0.13
HNSC	chr15	62762422	Missense_Mutation	rs750169478	D1644N	0.28
HNSC	chr15	62781171	Missense_Mutation	novel	G1849A	0.22
HNSC	chr15	62650136	Nonsense_Mutation	novel	W63*	0.07
HNSC	chr15	62781161	Missense_Mutation	novel	E1846K	0.21
HNSC	chr15	62694352	Missense_Mutation	novel	E418K	0.27
HNSC	chr15	62740470	Intron	novel		0.62
HNSC	chr15	62701162	Silent	novel	S548S	0.08
HNSC	chr15	62833648	Intron	novel		0.44
HNSC	chr15	62783879	Nonsense_Mutation	novel	E1909*	0.21
HNSC	chr15	62754043	Intron	novel		0.3
KIRC	chr15	62800689	Missense_Mutation	rs779433875	V2133I	0.35
KIRC	chr15	62738244	Missense_Mutation	NA	N1200D	0.36
KIRC	chr15	62833519	Missense_Mutation	NA	L2340M	0.1
KIRC	chr15	62771074	Silent	novel	T1769T	0.3
KIRC	chr15	62833559	Frame_Shift_Del	novel	*I2353Mfs42**	0.13
KIRC	chr15	62754003	Intron	novel		0.31
KIRC	chr15	62652104	Nonsense_Mutation	novel	*L113Nfs3**	0.05
KIRC	chr15	62652106	Silent	novel	E112E	0.01
KIRC	chr15	62738275	Missense_Mutation	NA	D1210V	0.36
KIRC	chr15	62708620	Missense_Mutation	NA	S764T	0.2
KIRC	chr15	62686778	Silent	rs750629080	S365S	0.19
KIRC	chr15	62707221	Missense_Mutation	novel	L714V	0.27
KIRP	chr15	62820531	Frame_Shift_Ins	novel	*E2309Rfs14**	0.28
KIRP	chr15	62719788	Missense_Mutation	NA	Q967E	0.37
KIRP	chr15	62805760	Missense_Mutation	NA	V2213E	0.29
KIRP	chr15	62781142	Frame_Shift_Del	novel	*D1840Mfs28**	0.39
KIRP	chr15	62752314	Missense_Mutation	novel	E1407K	0.36
LGG	chr15	62717594	Missense_Mutation	rs776142002	A928T	0.13
LGG	chr15	62835760	Silent	NA	A2384A	0.19
LGG	chr15	62647352	Silent	rs144527579	N14N	0.5
LGG	chr15	62702031	Missense_Mutation	rs760573881	A579V	0.42
LGG	chr15	62725092	Silent	novel	L1081L	0.38
LGG	chr15	62740770	Splice_Site	NA	X1342_splice	0.48
LIHC	chr15	62797362	Missense_Mutation	novel	L2065Q	0.32
LIHC	chr15	62717621	Missense_Mutation	novel	A937T	0.36
LIHC	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.39
LIHC	chr15	62739356	Silent	NA	P1232P	0.19
LIHC	chr15	62809926	Missense_Mutation	NA	Q2222P	0.51
LIHC	chr15	62707161	Nonsense_Mutation	novel	Q694*	0.32
LIHC	chr15	62697838	Silent	novel	G481G	0.46
LIHC	chr15	62776831	Missense_Mutation	novel	M1812T	0.46
LUAD	chr15	62766386	Silent	NA	T1720T	0.44
LUAD	chr15	62797269	Frame_Shift_Del	novel	*V2035Cfs47**	0.14
LUAD	chr15	62792683	Missense_Mutation	novel	G1927C	0.12
LUAD	chr15	62776909	Missense_Mutation	NA	K1838M	0.51
LUAD	chr15	62738334	Splice_Site	novel	X1229_splice	0.09
LUAD	chr15	62748442	Missense_Mutation	novel	E1373K	0.19
LUAD	chr15	62809955	Nonsense_Mutation	NA	E2232*	0.31
LUAD	chr15	62763614	Silent	novel	N1671N	0.21
LUAD	chr15	62840587	Missense_Mutation	NA	E2536K	0.2
LUAD	chr15	62727132	Missense_Mutation	novel	G1101C	0.12
LUAD	chr15	62719791	Silent	NA	L968L	0.52
LUAD	chr15	62783939	Intron	novel		0.12
LUAD	chr15	62647428	Missense_Mutation	novel	E40K	0.12
LUAD	chr15	62716375	Silent	NA	L893L	0.16
LUAD	chr15	62739404	Silent	novel	A1248A	0.33
LUAD	chr15	62686707	Missense_Mutation	novel	R342C	0.1
LUAD	chr15	62722470	Missense_Mutation	NA	R1037C	0.17
LUAD	chr15	62740555	Intron	novel		0.33
LUAD	chr15	62763588	Missense_Mutation	novel	C1663R	0.17
LUAD	chr15	62800666	Missense_Mutation	rs751562253	N2125S	0.07
LUAD	chr15	62647437	Missense_Mutation	NA	T43A	0.04
LUAD	chr15	62809960	Silent	rs766231592	V2233V	0.05
LUAD	chr15	62739394	Missense_Mutation	NA	N1245I	0.21
LUAD	chr15	62702825	Silent	NA	L655L	0.19
LUAD	chr15	62761762	Silent	novel	L1574L	0.1
LUAD	chr15	62739449	Silent	novel	R1263R	0.45
LUAD	chr15	62800403	Missense_Mutation	NA	K2090N	0.36
LUAD	chr15	62652049	Silent	rs767412321	R93R	0.28
LUAD	chr15	62655981	Missense_Mutation	novel	Q185H	0.15
LUAD	chr15	62766394	Missense_Mutation	novel	R1723L	0.56
LUAD	chr15	62771030	Missense_Mutation	rs756415845	L1755V	0.34
LUAD	chr15	62736876	Splice_Site	NA	X1120_splice	0.35
LUAD	chr15	62781182	Missense_Mutation	NA	D1853Y	0.27
LUAD	chr15	62711932	Missense_Mutation	NA	R830L	0.34
LUAD	chr15	62655950	Nonsense_Mutation	novel	W175*	0.31
LUAD	chr15	62655951	Missense_Mutation	novel	W175C	0.31
LUAD	chr15	62697770	Missense_Mutation	novel	G459C	0.41
LUAD	chr15	62686770	Missense_Mutation	novel	A363T	0.08
LUAD	chr15	62647420	Missense_Mutation	NA	R37L	0.31
LUAD	chr15	62752313	Frame_Shift_Del	novel	*E1407Nfs32**	0.15
LUAD	chr15	62737038	Missense_Mutation	novel	Q1173H	0.3
LUAD	chr15	62755460	Intron	novel		0.55
LUAD	chr15	62701163	Missense_Mutation	NA	Q549E	0.25
LUSC	chr15	62755453	Intron	novel		0.19
LUSC	chr15	62652124	Silent	NA	C118C	0.44
LUSC	chr15	62647428	Missense_Mutation	novel	E40Q	0.09
LUSC	chr15	62657843	Missense_Mutation	novel	A245S	0.32
LUSC	chr15	62762451	Missense_Mutation	NA	I1653M	0.34
LUSC	chr15	62739512	Silent	rs560735833	L1284L	0.31
LUSC	chr15	62776909	Missense_Mutation	NA	K1838M	0.24
LUSC	chr15	62792781	Silent	NA	T1959T	0.22
LUSC	chr15	62708728	Missense_Mutation	novel	R800P	0.35
LUSC	chr15	62727155	Silent	novel	L1108L	0.09
LUSC	chr15	62838943	Missense_Mutation	novel	V2488F	0.36
LUSC	chr15	62819615	Missense_Mutation	NA	M2291V	0.65
LUSC	chr15	62736967	Missense_Mutation	rs765379062	A1150T	0.16
LUSC	chr15	62650096	Missense_Mutation	novel	G50E	0.16
LUSC	chr15	62701106	Missense_Mutation	novel	A530S	0.21
LUSC	chr15	62653229	Frame_Shift_Del	novel	*G145Afs19**	0.47
LUSC	chr15	62753785	Missense_Mutation	NA	V1449F	0.11
LUSC	chr15	62647402	Frame_Shift_Del	novel	*R32Hfs7**	0.06
LUSC	chr15	62761761	Missense_Mutation	novel	N1573K	0.8
LUSC	chr15	62702774	Missense_Mutation	novel	Q638H	0.32
LUSC	chr15	62753862	Missense_Mutation	NA	Q1474H	0.11
LUSC	chr15	62740568	Intron	novel		0.09
LUSC	chr15	62702029	Silent	novel	C578C	0.18
LUSC	chr15	62836036	Missense_Mutation	novel	K2446R	0.21
LUSC	chr15	62708768	Missense_Mutation	NA	E813D	0.32
LUSC	chr15	62840613	3'UTR	novel		0.78
LUSC	chr15	62707176	Missense_Mutation	novel	T699A	0.34
LUSC	chr15	62752337	Silent	NA	Q1414Q	0.26
LUSC	chr15	62833510	Missense_Mutation	novel	D2337N	0.26
LUSC	chr15	62655955	Missense_Mutation	NA	D177Y	0.21
LUSC	chr15	62819582	Missense_Mutation	novel	A2280S	0.39
LUSC	chr15	62736897	Silent	NA	T1126T	0.32
LUSC	chr15	62711927	Missense_Mutation	novel	Q828H	0.64
LUSC	chr15	62711928	Missense_Mutation	novel	A829S	0.65
LUSC	chr15	62712077	Missense_Mutation	NA	K878N	0.35
LUSC	chr15	62716387	Silent	novel	A897A	0.26
LUSC	chr15	62722453	Missense_Mutation	NA	T1031I	0.19
LUSC	chr15	62753785	Missense_Mutation	NA	V1449F	0.11
LUSC	chr15	62736898	Missense_Mutation	novel	A1127S	0.07
LUSC	chr15	62701136	Missense_Mutation	rs780454196	D540N	0.07
LUSC	chr15	62686780	Missense_Mutation	novel	P366L	0.09
LUSC	chr15	62739471	Missense_Mutation	novel	A1271T	0.33
LUSC	chr15	62792787	Missense_Mutation	NA	K1961N	0.13
LUSC	chr15	62727165	Missense_Mutation	NA	A1112S	0.31
LUSC	chr15	62686741	Missense_Mutation	novel	E353G	0.27
LUSC	chr15	62647422	Missense_Mutation	novel	V38L	0.33
LUSC	chr15	62820553	Frame_Shift_Del	novel	*S2316Lfs6**	0.65
LUSC	chr15	62800384	Missense_Mutation	novel	A2084V	0.54
LUSC	chr15	62740739	Missense_Mutation	rs776896175	N1332S	0.12
LUSC	chr15	62719847	Silent	NA	L986L	0.15
LUSC	chr15	62707122	Missense_Mutation	novel	A681T	0.45
LUSC	chr15	62647419	Silent	novel	R37R	0.28
LUSC	chr15	62761819	Nonsense_Mutation	novel	E1593*	0.17
MESO	chr15	62762366	Missense_Mutation	novel	N1625S	0.37
MESO	chr15	62656044	Silent	novel	V206V	0.09
MESO	chr15	62727112	Missense_Mutation	novel	G1094E	0.28
OV	chr15	62833858	Intron	novel		0.16
OV	chr15	62752349	Silent	novel	T1418T	0.05
OV	chr15	62819534	Missense_Mutation	NA	P2264A	0.28
OV	chr15	62739420	Missense_Mutation	novel	S1254T	0.06
OV	chr15	62736966	Silent	rs376384348	A1149A	0.2
OV	chr15	62800396	Missense_Mutation	novel	V2088E	0.08
OV	chr15	62820544	Silent	NA	G2312G	0.45
OV	chr15	62702802	Nonsense_Mutation	novel	G648*	0.05
OV	chr15	62833461	Intron	novel		0.07
OV	chr15	62820608	Missense_Mutation	NA	K2334E	0.53
OV	chr15	62838855	Splice_Site	NA	X2459_splice	0.63
OV	chr15	62656002	Silent	NA	T192T	0.31
OV	chr15	62722378	Frame_Shift_Del	NA	K1007*	0.28
OV	chr15	62697744	Frame_Shift_Ins	novel	*A451Gfs14**	0.13
OV	chr15	62800445	Missense_Mutation	novel	S2104R	0.07
OV	chr15	62770967	Missense_Mutation	novel	T1734S	0.1
OV	chr15	62740743	Silent	rs147516120	A1333A	0.09
OV	chr15	62833522	Missense_Mutation	rs760063033	D2341N	0.23
OV	chr15	62833577	Frame_Shift_Ins	novel	*L2360Pfs51**	0.07
OV	chr15	62833835	Intron	novel		0.75
OV	chr15	62762422	Missense_Mutation	rs750169478	D1644N	0.08
PAAD	chr15	62740712	Missense_Mutation	novel	S1323F	0.24
PAAD	chr15	62656060	Missense_Mutation	rs763045450	V212M	0.1
PAAD	chr15	62701189	Silent	rs747382018	T557T	0.16
PAAD	chr15	62797385	Missense_Mutation	rs780860133	D2073N	0.05
PAAD	chr15	62727127	Missense_Mutation	rs201378780	A1099V	0.16
PAAD	chr15	62737042	Silent	rs774148194	L1175L	0.08
PAAD	chr15	62792685	Silent	novel	G1927G	0.21
PAAD	chr15	62762331	Silent	rs138708550	S1613S	0.04
PRAD	chr15	62686670	Silent	rs369934703	V329V	0.26
PRAD	chr15	62763589	Missense_Mutation	novel	C1663F	0.41
PRAD	chr15	62692885	Missense_Mutation	NA	E387K	0.3
PRAD	chr15	62717682	Missense_Mutation	novel	S957N	0.33
PRAD	chr15	62702018	Missense_Mutation	novel	A575T	0.19
PRAD	chr15	62833575	Silent	rs758459760	S2358S	0.44
READ	chr15	62738249	Silent	rs746828587	C1201C	0.2
READ	chr15	62748441	Silent	NA	L1372L	0.4
READ	chr15	62657794	Silent	rs759817353	G228G	0.35
READ	chr15	62652042	Missense_Mutation	NA	K91I	0.4
READ	chr15	62740712	Missense_Mutation	novel	S1323Y	0.42
READ	chr15	62748441	Silent	NA	L1372L	0.32
READ	chr15	62752400	Silent	novel	L1435L	0.38
READ	chr15	62766372	Missense_Mutation	novel	D1716N	0.37
READ	chr15	62792643	Splice_Region	rs752509413	I1913I	0.41
READ	chr15	62840562	Missense_Mutation	novel	Q2527H	0.31
READ	chr15	62771077	Silent	rs200255870	L1770L	0.3
SARC	chr15	62740529	Intron	novel		0.24
SARC	chr15	62694379	Missense_Mutation	rs757965110	V427I	0.4
SARC	chr15	62763680	Silent	rs370731939	D1693D	0.68
SARC	chr15	62805617	Silent	NA	D2165D	0.13
SARC	chr15	62653194	Nonsense_Mutation	novel	Q133*	0.18
SARC	chr15	62835741	Missense_Mutation	novel	G2378V	0.09
SARC	chr15	62736876	Splice_Site	novel	X1120_splice	0.42
SARC	chr15	62702153	Missense_Mutation	novel	G620R	0.35
SKCM	chr15	62755611	Missense_Mutation	NA	A1519V	0.21
SKCM	chr15	62740585	Intron	novel		0.18
SKCM	chr15	62694331	Nonsense_Mutation	NA	R411*	0.18
SKCM	chr15	62708510	Silent	NA	S727S	0.29
SKCM	chr15	62840497	Missense_Mutation	novel	E2506K	0.28
SKCM	chr15	62712002	Missense_Mutation	novel	M853I	0.22
SKCM	chr15	62739509	Silent	NA	F1283F	0.22
SKCM	chr15	62740614	Intron	novel		0.16
SKCM	chr15	62694378	Silent	rs140582507	S426S	0.4
SKCM	chr15	62740750	Missense_Mutation	novel	L1336F	0.35
SKCM	chr15	62819519	Missense_Mutation	NA	L2259F	0.27
SKCM	chr15	62716456	Silent	novel	L920L	0.81
SKCM	chr15	62675301	Missense_Mutation	rs750791867	V313M	0.34
SKCM	chr15	62740472	Intron	novel		0.2
SKCM	chr15	62737040	Missense_Mutation	NA	A1174V	0.1
SKCM	chr15	62752333	Missense_Mutation	novel	S1413L	0.09
SKCM	chr15	62792760	Silent	rs749661984	I1952I	0.18
SKCM	chr15	62719785	Missense_Mutation	rs750174235	P966S	0.64
SKCM	chr15	62727177	Missense_Mutation	rs200129296	E1116K	0.14
SKCM	chr15	62755636	Silent	NA	F1527F	0.15
SKCM	chr15	62833371	Intron	novel		0.46
SKCM	chr15	62697772	Silent	NA	G459G	0.52
SKCM	chr15	62781156	Missense_Mutation	rs780528638	P1844L	0.44
SKCM	chr15	62647413	Missense_Mutation	rs539152254	R35W	0.84
SKCM	chr15	62797265	Silent	novel	L2033L	0.82
SKCM	chr15	62792760	Silent	rs749661984	I1952I	0.21
SKCM	chr15	62835798	Missense_Mutation	novel	A2397V	0.37
SKCM	chr15	62835995	Silent	rs202049914	V2432V	0.42
SKCM	chr15	62702140	Silent	novel	A615A	0.26
SKCM	chr15	62708511	Missense_Mutation	NA	P728S	0.08
SKCM	chr15	62797332	Missense_Mutation	NA	T2055I	0.36
SKCM	chr15	62692901	Missense_Mutation	NA	S392F	0.41
SKCM	chr15	62833623	Silent	NA	Q2374Q	0.38
SKCM	chr15	62650168	Missense_Mutation	novel	M74R	0.38
SKCM	chr15	62701138	Silent	rs139848057	D540D	0.09
SKCM	chr15	62697775	Silent	rs576870593	S460S	0.16
SKCM	chr15	62694384	Silent	NA	S428S	0.29
SKCM	chr15	62702032	Silent	NA	A579A	0.37
SKCM	chr15	62833444	Intron	novel		0.43
SKCM	chr15	62800694	Silent	novel	K2134K	0.18
SKCM	chr15	62836097	Intron	novel		0.2
SKCM	chr15	62675276	Silent	rs199806066	L304L	0.41
SKCM	chr15	62653224	Missense_Mutation	NA	G143R	0.28
SKCM	chr15	62650104	Missense_Mutation	NA	L53F	0.28
SKCM	chr15	62708695	Missense_Mutation	rs768628001	R789Q	0.18
SKCM	chr15	62740614	Intron	novel		0.12
SKCM	chr15	62800404	Missense_Mutation	novel	A2091S	0.32
SKCM	chr15	62800405	Missense_Mutation	rs748536008	A2091V	0.33
SKCM	chr15	62753801	Missense_Mutation	NA	P1454L	0.2
SKCM	chr15	62762410	Missense_Mutation	NA	H1640Y	0.36
SKCM	chr15	62835979	Missense_Mutation	NA	S2427L	0.44
SKCM	chr15	62833491	Intron	novel		0.23
SKCM	chr15	62797301	Missense_Mutation	NA	L2045M	0.41
SKCM	chr15	62838863	Missense_Mutation	NA	G2461E	0.45
SKCM	chr15	62740615	Intron	novel		0.46
SKCM	chr15	62647331	Silent	rs536031805	K7K	0.38
SKCM	chr15	62686716	Frame_Shift_Del	novel	*E345Vfs47**	0.32
SKCM	chr15	62835748	Silent	NA	I2380I	0.37
SKCM	chr15	62800433	Silent	NA	K2100K	0.16
SKCM	chr15	62783910	Intron	novel		0.17
SKCM	chr15	62833510	Missense_Mutation	novel	D2337N	0.21
SKCM	chr15	62805757	Missense_Mutation	novel	A2212V	0.31
SKCM	chr15	62692901	Missense_Mutation	NA	S392F	0.3
SKCM	chr15	62809957	Silent	novel	E2232E	0.11
SKCM	chr15	62809958	Missense_Mutation	NA	V2233M	0.11
SKCM	chr15	62657785	Silent	NA	I225I	0.39
SKCM	chr15	62740676	Missense_Mutation	novel	S1311L	0.34
SKCM	chr15	62748387	Silent	novel	L1354L	0.41
SKCM	chr15	62748388	Missense_Mutation	novel	C1355S	0.4
SKCM	chr15	62762296	Silent	rs756323778	L1602L	0.42
SKCM	chr15	62701207	Silent	NA	L563L	0.42
SKCM	chr15	62763560	Splice_Region	novel		0.1
SKCM	chr15	62840617	3'UTR	novel		0.14
SKCM	chr15	62653193	Silent	novel	I132I	0.6
SKCM	chr15	62697754	Silent	rs767329386	P453P	0.34
SKCM	chr15	62755534	Splice_Region	NA	V1493V	0.35
SKCM	chr15	62835745	Silent	rs751409298	S2379S	0.19
SKCM	chr15	62755617	Missense_Mutation	NA	P1521L	0.48
SKCM	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.26
SKCM	chr15	62719788	Nonsense_Mutation	NA	Q967*	0.22
SKCM	chr15	62652046	Silent	novel	I92I	0.55
SKCM	chr15	62655997	Missense_Mutation	rs377295412	E191K	0.62
SKCM	chr15	62655955	Missense_Mutation	NA	D177N	0.34
SKCM	chr15	62805662	Silent	rs760232975	T2180T	0.23
SKCM	chr15	62820594	Missense_Mutation	rs748045275	P2329L	0.52
STAD	chr15	62797368	Missense_Mutation	novel	A2067V	0.17
STAD	chr15	62776872	Frame_Shift_Del	novel	*G1827Afs10**	0.2
STAD	chr15	62708710	Missense_Mutation	rs145362831	R794Q	0.46
STAD	chr15	62739469	Missense_Mutation	novel	A1270V	0.29
STAD	chr15	62755544	Missense_Mutation	rs373813759	A1497T	0.58
STAD	chr15	62647438	Missense_Mutation	NA	T43I	0.08
STAD	chr15	62653298	Silent	novel	L167L	0.09
STAD	chr15	62653267	Missense_Mutation	novel	E157G	0.08
STAD	chr15	62748378	Silent	NA	L1351L	0.37
STAD	chr15	62792776	Missense_Mutation	rs375769813	V1958I	0.45
STAD	chr15	62708510	Silent	NA	S727S	0.18
STAD	chr15	62673849	Missense_Mutation	NA	E271K	0.31
STAD	chr15	62776886	Silent	rs200962160	D1830D	0.28
STAD	chr15	62716420	Silent	novel	A908A	0.09
STAD	chr15	62836089	Intron	novel		0.32
STAD	chr15	62762365	Missense_Mutation	NA	N1625D	0.24
STAD	chr15	62736991	Nonsense_Mutation	NA	R1158*	0.35
STAD	chr15	62740568	Intron	novel		0.31
STAD	chr15	62697853	Silent	novel	G486G	0.27
STAD	chr15	62776844	Silent	rs374140330	N1816N	0.5
STAD	chr15	62833484	Intron	novel		0.15
STAD	chr15	62752403	Nonsense_Mutation	NA	C1436*	0.42
STAD	chr15	62761684	Missense_Mutation	NA	L1548M	0.07
STAD	chr15	62653312	Missense_Mutation	NA	D172V	0.11
STAD	chr15	62739536	Silent	NA	G1292G	0.1
STAD	chr15	62797249	Silent	rs769329836	L2027L	0.22
STAD	chr15	62725105	Splice_Site	novel	X1085_splice	0.19
STAD	chr15	62702089	Silent	rs539209082	A598A	0.26
STAD	chr15	62711990	Silent	NA	A849A	0.15
STAD	chr15	62737031	Missense_Mutation	novel	A1171V	0.47
STAD	chr15	62805775	Missense_Mutation	rs759956625	T2218M	0.24
STAD	chr15	62722410	Missense_Mutation	novel	A1017P	0.21
STAD	chr15	62647341	Missense_Mutation	rs771261514	R11C	0.11
STAD	chr15	62739362	Silent	rs367811145	T1234T	0.28
STAD	chr15	62776815	Missense_Mutation	NA	A1807T	0.09
STAD	chr15	62736997	Missense_Mutation	rs140997624	V1160M	0.17
STAD	chr15	62686764	Missense_Mutation	rs765543453	R361C	0.2
STAD	chr15	62711923	Missense_Mutation	rs749680451	R827H	0.21
STAD	chr15	62697716	Missense_Mutation	rs201978847	R441W	0.34
STAD	chr15	62781198	Missense_Mutation	NA	V1858A	0.33
STAD	chr15	62763615	Missense_Mutation	rs373058762	R1672W	0.26
STAD	chr15	62792771	Missense_Mutation	rs555995247	R1956H	0.11
STAD	chr15	62755588	Silent	NA	C1511C	0.25
STAD	chr15	62736899	Missense_Mutation	novel	A1127V	0.33
STAD	chr15	62653308	Missense_Mutation	NA	D171N	0.35
STAD	chr15	62657813	Missense_Mutation	rs532505276	E235K	0.14
STAD	chr15	62740613	Intron	novel		0.27
STAD	chr15	62737012	Missense_Mutation	NA	A1165T	0.29
STAD	chr15	62717678	Nonsense_Mutation	NA	Q956*	0.41
STAD	chr15	62727153	Silent	NA	L1108L	0.25
STAD	chr15	62800729	Missense_Mutation	rs748387093	A2146V	0.37
STAD	chr15	62686709	Silent	rs767806424	R342R	0.16
THCA	chr15	62809971	Missense_Mutation	novel	A2237D	0.21
THCA	chr15	62702831	Missense_Mutation	NA	Q657H	0.47
UCEC	chr15	62647405	Missense_Mutation	rs554667095	R32Q	0.32
UCEC	chr15	62740743	Silent	rs147516120	A1333A	0.4
UCEC	chr15	62833491	Intron	novel		0.3
UCEC	chr15	62694373	Nonsense_Mutation	novel	E425*	0.45
UCEC	chr15	62650162	Missense_Mutation	NA	Y72C	0.26
UCEC	chr15	62708592	Missense_Mutation	rs148053073	R755C	0.2
UCEC	chr15	62766359	Silent	rs139582651	I1711I	0.31
UCEC	chr15	62819570	Nonsense_Mutation	NA	R2276*	0.23
UCEC	chr15	62647436	Missense_Mutation	novel	Q42H	0.17
UCEC	chr15	62697796	Silent	rs773713515	N467N	0.26
UCEC	chr15	62711922	Missense_Mutation	novel	R827C	0.3
UCEC	chr15	62716412	Missense_Mutation	NA	A906S	0.5
UCEC	chr15	62738215	Missense_Mutation	novel	V1190A	0.31
UCEC	chr15	62763633	Missense_Mutation	novel	E1678K	0.09
UCEC	chr15	62809980	Missense_Mutation	novel	F2240S	0.26
UCEC	chr15	62719865	Silent	novel	S992S	0.51
UCEC	chr15	62750454	Missense_Mutation	novel	Y1391C	0.07
UCEC	chr15	62796293	Missense_Mutation	novel	R2017M	0.32
UCEC	chr15	62722395	Missense_Mutation	novel	T1012A	0.22
UCEC	chr15	62736991	Nonsense_Mutation	NA	R1158*	0.19
UCEC	chr15	62740539	Intron	novel		0.31
UCEC	chr15	62702856	Nonsense_Mutation	novel	R666*	0.45
UCEC	chr15	62711922	Missense_Mutation	novel	R827C	0.33
UCEC	chr15	62716451	Nonsense_Mutation	NA	R919*	0.3
UCEC	chr15	62762370	Silent	novel	P1626P	0.32
UCEC	chr15	62820564	Missense_Mutation	novel	A2319D	0.44
UCEC	chr15	62838898	Missense_Mutation	rs565347411	R2473C	0.56
UCEC	chr15	62820560	Missense_Mutation	NA	E2318K	0.16
UCEC	chr15	62738248	Missense_Mutation	novel	C1201Y	0.08
UCEC	chr15	62805732	Missense_Mutation	NA	A2204T	0.22
UCEC	chr15	62754060	Intron	novel		0.22
UCEC	chr15	62840760	3'UTR	novel		0.15
UCEC	chr15	62736962	Missense_Mutation	rs768697506	A1148V	0.5
UCEC	chr15	62697748	Silent	rs372984234	A451A	0.54
UCEC	chr15	62736992	Missense_Mutation	rs759597569	R1158Q	0.45
UCEC	chr15	62650170	Silent	novel	L75L	0.09
UCEC	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.14
UCEC	chr15	62686674	Missense_Mutation	rs778567163	R331C	0.22
UCEC	chr15	62708643	Missense_Mutation	rs150742531	A772T	0.12
UCEC	chr15	62833578	Silent	NA	A2359A	0.21
UCEC	chr15	62697700	Silent	novel	L435L	0.19
UCEC	chr15	62752419	Missense_Mutation	rs770642632	A1442T	0.22
UCEC	chr15	62650173	Missense_Mutation	NA	R76G	0.45
UCEC	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.49
UCEC	chr15	62698838	Missense_Mutation	novel	D520N	0.52
UCEC	chr15	62708714	Silent	NA	G795G	0.33
UCEC	chr15	62820538	Silent	NA	L2310L	0.46
UCEC	chr15	62737011	Silent	rs769114416	S1164S	0.48
UCEC	chr15	62792682	Silent	rs769000863	H1926H	0.5
UCEC	chr15	62673834	Nonsense_Mutation	novel	E266*	0.35
UCEC	chr15	62675276	Silent	rs199806066	L304L	0.23
UCEC	chr15	62738332	Missense_Mutation	rs758650990	S1229L	0.46
UCEC	chr15	62748441	Silent	NA	L1372L	0.44
UCEC	chr15	62766343	Missense_Mutation	rs142261304	S1706L	0.38
UCEC	chr15	62702092	Silent	novel	A599A	0.22
UCEC	chr15	62708623	Missense_Mutation	novel	E765G	0.25
UCEC	chr15	62809995	Missense_Mutation	novel	T2245I	0.24
UCEC	chr15	62833371	Intron	novel		0.44
UCEC	chr15	62840837	3'UTR	novel		0.19
UCEC	chr15	62750403	Missense_Mutation	novel	T1374I	0.18
UCEC	chr15	62771077	Silent	rs200255870	L1770L	0.28
UCEC	chr15	62820612	Splice_Site	novel	X2334_splice	0.4
UCEC	chr15	62763644	Silent	rs755561842	S1681S	0.36
UCEC	chr15	62796239	Missense_Mutation	novel	F1999S	0.41
UCEC	chr15	62707170	Missense_Mutation	novel	E697K	0.36
UCEC	chr15	62748421	Missense_Mutation	novel	D1366N	0.37
UCEC	chr15	62805662	Silent	rs760232975	T2180T	0.36
UCEC	chr15	62800458	Missense_Mutation	rs543868821	D2109N	0.47
UCEC	chr15	62653228	Missense_Mutation	rs142023685	T144M	0.44
UCEC	chr15	62737003	Missense_Mutation	novel	E1162K	0.63
UCEC	chr15	62762331	Silent	rs138708550	S1613S	0.42
UCEC	chr15	62841304	3'UTR	novel		0.48
UCEC	chr15	62712079	Splice_Site	novel	X878_splice	0.33
UCEC	chr15	62740742	Missense_Mutation	rs369042993	A1333V	0.43
UCEC	chr15	62755361	Intron	novel		0.5
UCEC	chr15	62650109	Silent	NA	S54S	0.29
UCEC	chr15	62840783	3'UTR	novel		0.67
UCEC	chr15	62675280	Missense_Mutation	rs774116063	R306W	0.46
UCEC	chr15	62752308	Missense_Mutation	novel	L1405M	0.44
UCEC	chr15	62833491	Intron	novel		0.43
UCEC	chr15	62835917	Missense_Mutation	novel	S2406R	0.3
UCEC	chr15	62840556	Silent	novel	I2525I	0.6
UCEC	chr15	62840783	3'UTR	novel		0.35
UCEC	chr15	62655986	Missense_Mutation	novel	V187A	0.36
UCEC	chr15	62740472	Intron	novel		0.23
UCEC	chr15	62701183	Silent	rs753474101	A555A	0.25
UCEC	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.36
UCEC	chr15	62701151	Missense_Mutation	rs776746143	E545K	0.18
UCEC	chr15	62736991	Nonsense_Mutation	NA	R1158*	0.22
UCEC	chr15	62809965	Missense_Mutation	novel	T2235I	0.31
UCEC	chr15	62820488	Missense_Mutation	novel	T2294A	0.47
UCEC	chr15	62840538	Frame_Shift_Ins	NA	*L2522Tfs10**	0.41
UCEC	chr15	62694386	Frame_Shift_Ins	novel	*S432Vfs33**	0.32
UCEC	chr15	62761751	Missense_Mutation	novel	A1570V	0.38
UCEC	chr15	62763633	Missense_Mutation	novel	E1678K	0.46
UCEC	chr15	62841270	3'UTR	novel		0.39
UCEC	chr15	62711960	Silent	NA	L839L	0.5
UCEC	chr15	62761773	Silent	rs375986590	F1577F	0.54
UCEC	chr15	62840998	3'UTR	novel		0.4
UCEC	chr15	62702157	Missense_Mutation	novel	A621V	0.14
UCEC	chr15	62722398	Missense_Mutation	rs141513413	V1013M	0.33
UCEC	chr15	62841213	3'UTR	novel		0.24
UCEC	chr15	62701139	Missense_Mutation	novel	E541K	0.37
UCEC	chr15	62738300	Silent	rs569421793	I1218I	0.33
UCEC	chr15	62739512	Silent	rs560735833	L1284L	0.46
UCEC	chr15	62740527	Intron	novel		0.49
UCEC	chr15	62763670	Missense_Mutation	novel	A1690V	0.47
UCEC	chr15	62835995	Silent	rs202049914	V2432V	0.41
UCEC	chr15	62840491	Missense_Mutation	rs760952896	A2504T	0.55
UCEC	chr15	62841335	3'UTR	novel		0.38
UCEC	chr15	62708693	Silent	novel	V788V	0.46
UCEC	chr15	62833858	Intron	novel		0.6
UCEC	chr15	62708733	Missense_Mutation	rs757307260	D802N	0.28
UCEC	chr15	62833539	Silent	NA	I2346I	0.14
UCEC	chr15	62653170	Missense_Mutation	NA	N125H	0.21
UCEC	chr15	62702150	Missense_Mutation	rs761751298	A619T	0.28
UCEC	chr15	62711968	Missense_Mutation	novel	A842V	0.2
UCEC	chr15	62724978	Splice_Region	novel	A1043A	0.38
UCEC	chr15	62783776	Silent	novel	T1874T	0.28
UCEC	chr15	62840765	3'UTR	novel		0.38
UCEC	chr15	62702087	Missense_Mutation	NA	A598T	0.18
UCEC	chr15	62708714	Silent	NA	G795G	0.28
UCEC	chr15	62755635	Missense_Mutation	NA	F1527S	0.12
UCEC	chr15	62762316	Missense_Mutation	NA	M1608I	0.1
UCEC	chr15	62833271	Intron	novel		0.13
UCEC	chr15	62762438	Missense_Mutation	NA	L1649P	0.35
UCEC	chr15	62716442	Missense_Mutation	novel	I916F	0.07
UCEC	chr15	62725072	Missense_Mutation	novel	E1075K	0.22
UCEC	chr15	62840713	3'UTR	novel		0.26
UCEC	chr15	62776812	Missense_Mutation	novel	E1806K	0.28
UCEC	chr15	62761760	Missense_Mutation	NA	N1573S	0.15
UCEC	chr15	62656049	Missense_Mutation	rs776986439	S208L	0.51
UCEC	chr15	62716451	Nonsense_Mutation	NA	R919*	0.4
UCEC	chr15	62740585	Intron	novel		0.36
UCEC	chr15	62819581	Silent	rs143080480	G2279G	0.52
UCEC	chr15	62736960	Silent	rs772544952	P1147P	0.55
UCEC	chr15	62740522	Intron	novel		0.38
UCEC	chr15	62753775	Splice_Region	NA	A1445A	0.19
UCEC	chr15	62754059	Intron	novel		0.2
UCEC	chr15	62754060	Intron	novel		0.18
UCEC	chr15	62792760	Silent	rs749661984	I1952I	0.33
UCEC	chr15	62797256	Missense_Mutation	NA	D2030Y	0.3
UCEC	chr15	62708609	Nonsense_Mutation	novel	*A760_T761insFTFPMGHHHQEHQ**	0.1
UCEC	chr15	62810017	Frame_Shift_Ins	novel	*E2253Ifs15**	0.06
UCEC	chr15	62675288	Silent	novel	L308L	0.34
UCEC	chr15	62711919	Missense_Mutation	novel	V826L	0.12
UCEC	chr15	62763602	Silent	rs140087396	I1667I	0.35
UCEC	chr15	62781173	Missense_Mutation	novel	T1850A	0.17
UCEC	chr15	62783984	Intron	novel		0.14
UCEC	chr15	62809955	Missense_Mutation	novel	E2232K	0.16
UCEC	chr15	62819607	Missense_Mutation	rs200020059	A2288V	0.39
UCEC	chr15	62833641	Intron	rs141794834		0.28
UCEC	chr15	62838890	Missense_Mutation	rs781005743	N2470S	0.19
UCEC	chr15	62840820	3'UTR	novel		0.4
UCEC	chr15	62707186	Missense_Mutation	rs779321310	Q702R	0.48
UCEC	chr15	62711912	Splice_Region	novel	G823G	0.47
UCEC	chr15	62838917	Missense_Mutation	NA	A2479V	0.23
UCEC	chr15	62755667	Missense_Mutation	NA	T1538A	0.55
UCEC	chr15	62647341	Missense_Mutation	rs771261514	R11C	0.08
UCEC	chr15	62697790	Silent	NA	T465T	0.33
UCEC	chr15	62755519	Intron	novel		0.21
UCEC	chr15	62761814	Missense_Mutation	rs141621869	S1591N	0.24
UCEC	chr15	62797280	Missense_Mutation	NA	A2038T	0.44
UCEC	chr15	62800398	Missense_Mutation	NA	A2089T	0.29
UCEC	chr15	62840550	Silent	NA	A2523A	0.18
UCEC	chr15	62762300	Missense_Mutation	novel	V1603D	0.45
UCEC	chr15	62781222	Missense_Mutation	rs377502147	A1866V	0.38
UCEC	chr15	62755572	Missense_Mutation	novel	A1506V	0.31
UCEC	chr15	62781181	Silent	rs746835387	V1852V	0.47
UCEC	chr15	62740674	Silent	novel	I1310I	0.36
UCEC	chr15	62841122	3'UTR	novel		0.28
UCS	chr15	62650136	Missense_Mutation	novel	W63C	0.87
UCS	chr15	62792776	Missense_Mutation	rs375769813	V1958I	0.3
UCS	chr15	62754011	Intron	novel		0.42
UVM	chr15	62736932	Missense_Mutation	rs750147149	R1138H	0.56

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KICH	AMP	0.2879	0.21756
KIRP	DEL	0.0972	0.2062
LGG	AMP	0.0156	0.19963
PAAD	AMP	0.0598	0.20695
PAAD	DEL	0.1141	0.13216
READ	DEL	0.4182	0.025797

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0025	Kaplan-Meier Survival Analysis
MESO	0.0019	Kaplan-Meier Survival Analysis
ACC	0.043	Kaplan-Meier Survival Analysis
SKCM	0.034	Kaplan-Meier Survival Analysis
LUSC	0.025	Kaplan-Meier Survival Analysis
BRCA	0.0012	Kaplan-Meier Survival Analysis
KIRP	0.00069	Kaplan-Meier Survival Analysis
READ	0.00022	Kaplan-Meier Survival Analysis
THCA	0.02	Kaplan-Meier Survival Analysis
UVM	0.037	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742