EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000173113 (Gene tree)
Gene ID: 51504
Gene Symbol: TRMT112
Alias: HSPC152|HSPC170|TRM112|TRMT11-2|hTrm112
Full Name: tRNA methyltransferase subunit 11-2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 1,625 bases
Position: chr11:64,316,460-64,318,084
Accession: 26940
RBP type: canonical RBP
Summary: (TRNA Methyltransferase Subunit 11-2) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include protein methyltransferase activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000438349	Trm112p	PF03966.16	2.3e-14	1	1
ENSP00000309433	Trm112p	PF03966.16	1.9e-12	1	1
ENSP00000441279	Trm112p	PF03966.16	7.9e-11	1	1
ENSP00000440437	Trm112p	PF03966.16	0.00054	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31328227	The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.	Nucleic Acids Res	2019 Jul 22	van Tran N	doi: 10.1093/nar/gkz619

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000535126	TRMT112-202	704	-	ENSP00000444082	63 (aa)	-	F5GZZ7
ENST00000544844	TRMT112-206	1106	XM_024448579	ENSP00000438349	125 (aa)	XP_024304347	Q9UI30
ENST00000535750	TRMT112-203	823	-	ENSP00000441279	81 (aa)	-	F5GYQ2
ENST00000539854	TRMT112-205	659	-	ENSP00000440437	106 (aa)	-	F5GX77
ENST00000537918	TRMT112-204	559	-	-	- (aa)	-	-
ENST00000308774	TRMT112-201	561	-	ENSP00000309433	120 (aa)	-	Q9UI30

Gene Model

Click here to download ENSG00000173113's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000173113	rs9787810	11	64317826	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000173113's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000173113	TRMT112	100	82.400	ENSAMEG00000017965	-	100	82.400	Ailuropoda_melanoleuca
ENSG00000173113	TRMT112	99	70.161	ENSAMEG00000020192	-	100	70.161	Ailuropoda_melanoleuca
ENSG00000173113	TRMT112	100	95.200	ENSANAG00000021626	-	100	95.200	Aotus_nancymaae
ENSG00000173113	TRMT112	99	81.250	ENSANAG00000025496	-	100	72.000	Aotus_nancymaae
ENSG00000173113	TRMT112	90	71.681	ENSBTAG00000047194	-	96	71.681	Bos_taurus
ENSG00000173113	TRMT112	100	84.000	ENSBTAG00000008646	TRMT112	100	84.000	Bos_taurus
ENSG00000173113	TRMT112	100	92.593	ENSCJAG00000018026	-	100	92.000	Callithrix_jacchus
ENSG00000173113	TRMT112	100	83.200	ENSCAFG00000014445	TRMT112	100	83.200	Canis_familiaris
ENSG00000173113	TRMT112	100	83.200	ENSCAFG00020014158	TRMT112	100	83.200	Canis_lupus_dingo
ENSG00000173113	TRMT112	100	84.000	ENSCHIG00000023970	-	100	84.000	Capra_hircus
ENSG00000173113	TRMT112	100	84.000	ENSCHIG00000013770	-	100	84.000	Capra_hircus
ENSG00000173113	TRMT112	93	82.143	ENSTSYG00000025753	TRMT112	100	82.143	Carlito_syrichta
ENSG00000173113	TRMT112	100	81.600	ENSCPOG00000030092	TRMT112	95	81.600	Cavia_porcellus
ENSG00000173113	TRMT112	100	82.716	ENSCCAG00000035429	-	100	75.200	Cebus_capucinus
ENSG00000173113	TRMT112	100	84.800	ENSCCAG00000028799	-	100	84.800	Cebus_capucinus
ENSG00000173113	TRMT112	100	94.400	ENSCCAG00000028185	-	100	94.400	Cebus_capucinus
ENSG00000173113	TRMT112	100	83.951	ENSCATG00000039283	-	100	83.951	Cercocebus_atys
ENSG00000173113	TRMT112	100	98.400	ENSCATG00000037611	-	100	98.400	Cercocebus_atys
ENSG00000173113	TRMT112	100	81.600	ENSCLAG00000016885	TRMT112	100	81.600	Chinchilla_lanigera
ENSG00000173113	TRMT112	100	98.400	ENSCSAG00000007187	-	100	98.400	Chlorocebus_sabaeus
ENSG00000173113	TRMT112	100	97.600	ENSCSAG00000000388	-	100	97.600	Chlorocebus_sabaeus
ENSG00000173113	TRMT112	100	99.200	ENSCANG00000043448	-	100	99.200	Colobus_angolensis_palliatus
ENSG00000173113	TRMT112	100	99.200	ENSCANG00000007652	-	100	99.200	Colobus_angolensis_palliatus
ENSG00000173113	TRMT112	100	80.800	ENSCGRG00001018319	Trmt112	100	80.800	Cricetulus_griseus_chok1gshd
ENSG00000173113	TRMT112	100	80.800	ENSCGRG00000009853	Trmt112	100	80.800	Cricetulus_griseus_crigri
ENSG00000173113	TRMT112	100	81.600	ENSDNOG00000046974	-	100	81.600	Dasypus_novemcinctus
ENSG00000173113	TRMT112	100	84.000	ENSDNOG00000036525	-	100	84.000	Dasypus_novemcinctus
ENSG00000173113	TRMT112	100	80.000	ENSDORG00000012328	Trmt112	100	80.000	Dipodomys_ordii
ENSG00000173113	TRMT112	100	78.400	ENSETEG00000000263	TRMT112	100	78.400	Echinops_telfairi
ENSG00000173113	TRMT112	100	81.600	ENSEASG00005019934	TRMT112	100	81.600	Equus_asinus_asinus
ENSG00000173113	TRMT112	86	80.220	ENSECAG00000033970	-	61	80.189	Equus_caballus
ENSG00000173113	TRMT112	100	83.200	ENSFCAG00000023392	TRMT112	100	83.200	Felis_catus
ENSG00000173113	TRMT112	100	81.600	ENSFDAG00000007663	TRMT112	100	81.600	Fukomys_damarensis
ENSG00000173113	TRMT112	100	100.000	ENSGGOG00000001334	TRMT112	100	100.000	Gorilla_gorilla
ENSG00000173113	TRMT112	100	77.778	ENSGGOG00000038752	-	100	77.778	Gorilla_gorilla
ENSG00000173113	TRMT112	100	81.600	ENSHGLG00000011130	TRMT112	100	81.600	Heterocephalus_glaber_female
ENSG00000173113	TRMT112	100	81.600	ENSHGLG00100014193	TRMT112	100	81.600	Heterocephalus_glaber_male
ENSG00000173113	TRMT112	100	81.600	ENSSTOG00000019857	TRMT112	100	81.600	Ictidomys_tridecemlineatus
ENSG00000173113	TRMT112	100	78.400	ENSJJAG00000022077	Trmt112	100	78.400	Jaculus_jaculus
ENSG00000173113	TRMT112	100	81.600	ENSLAFG00000029149	TRMT112	100	81.600	Loxodonta_africana
ENSG00000173113	TRMT112	100	99.200	ENSMFAG00000044258	-	100	99.200	Macaca_fascicularis
ENSG00000173113	TRMT112	95	88.312	ENSMFAG00000029782	-	85	78.151	Macaca_fascicularis
ENSG00000173113	TRMT112	100	83.200	ENSMFAG00000033613	-	100	83.200	Macaca_fascicularis
ENSG00000173113	TRMT112	100	83.200	ENSMMUG00000029341	-	100	83.200	Macaca_mulatta
ENSG00000173113	TRMT112	100	99.200	ENSMMUG00000019647	TRMT112	100	99.200	Macaca_mulatta
ENSG00000173113	TRMT112	100	99.200	ENSMNEG00000013487	TRMT112	100	99.200	Macaca_nemestrina
ENSG00000173113	TRMT112	100	99.167	ENSMLEG00000017888	TRMT112	100	99.167	Mandrillus_leucophaeus
ENSG00000173113	TRMT112	98	65.823	ENSMAUG00000009833	-	100	58.974	Mesocricetus_auratus
ENSG00000173113	TRMT112	100	80.800	ENSMAUG00000013650	-	100	80.800	Mesocricetus_auratus
ENSG00000173113	TRMT112	100	83.200	ENSMICG00000016987	-	100	83.200	Microcebus_murinus
ENSG00000173113	TRMT112	100	76.543	ENSMICG00000031564	-	100	71.429	Microcebus_murinus
ENSG00000173113	TRMT112	100	80.000	ENSMOCG00000007447	-	100	80.000	Microtus_ochrogaster
ENSG00000173113	TRMT112	100	77.600	ENSMOCG00000001529	-	100	77.600	Microtus_ochrogaster
ENSG00000173113	TRMT112	100	80.800	MGP_CAROLIEiJ_G0022615	Trmt112	100	80.800	Mus_caroli
ENSG00000173113	TRMT112	100	80.800	ENSMUSG00000038812	Trmt112	100	80.800	Mus_musculus
ENSG00000173113	TRMT112	100	80.800	MGP_PahariEiJ_G0014109	Trmt112	100	80.800	Mus_pahari
ENSG00000173113	TRMT112	100	80.800	MGP_SPRETEiJ_G0023526	Trmt112	100	80.800	Mus_spretus
ENSG00000173113	TRMT112	100	84.000	ENSMPUG00000012911	TRMT112	100	84.000	Mustela_putorius_furo
ENSG00000173113	TRMT112	100	82.400	ENSMLUG00000008867	TRMT112	100	82.400	Myotis_lucifugus
ENSG00000173113	TRMT112	100	79.200	ENSNGAG00000019029	Trmt112	100	79.200	Nannospalax_galili
ENSG00000173113	TRMT112	100	99.167	ENSNLEG00000028260	TRMT112	100	99.167	Nomascus_leucogenys
ENSG00000173113	TRMT112	90	72.632	ENSOPRG00000004130	-	100	67.857	Ochotona_princeps
ENSG00000173113	TRMT112	88	78.182	ENSODEG00000019996	-	89	78.182	Octodon_degus
ENSG00000173113	TRMT112	100	67.901	ENSODEG00000011737	-	94	67.742	Octodon_degus
ENSG00000173113	TRMT112	100	76.543	ENSOCUG00000004445	-	100	76.147	Oryctolagus_cuniculus
ENSG00000173113	TRMT112	100	75.309	ENSOCUG00000027361	-	80	76.768	Oryctolagus_cuniculus
ENSG00000173113	TRMT112	100	82.400	ENSOGAG00000013535	TRMT112	100	82.400	Otolemur_garnettii
ENSG00000173113	TRMT112	100	84.000	ENSOARG00000006842	TRMT112	100	84.000	Ovis_aries
ENSG00000173113	TRMT112	100	100.000	ENSPPAG00000039858	TRMT112	100	100.000	Pan_paniscus
ENSG00000173113	TRMT112	100	83.200	ENSPPRG00000003855	-	100	83.200	Panthera_pardus
ENSG00000173113	TRMT112	100	82.400	ENSPTIG00000016927	TRMT112	100	82.400	Panthera_tigris_altaica
ENSG00000173113	TRMT112	100	100.000	ENSPTRG00000003834	TRMT112	100	100.000	Pan_troglodytes
ENSG00000173113	TRMT112	95	88.312	ENSPANG00000032340	-	85	78.151	Papio_anubis
ENSG00000173113	TRMT112	100	86.420	ENSPANG00000009935	-	100	86.420	Papio_anubis
ENSG00000173113	TRMT112	100	98.400	ENSPANG00000035234	-	100	98.400	Papio_anubis
ENSG00000173113	TRMT112	100	80.000	ENSPEMG00000014684	-	100	80.000	Peromyscus_maniculatus_bairdii
ENSG00000173113	TRMT112	94	70.940	ENSPEMG00000021482	-	100	70.940	Peromyscus_maniculatus_bairdii
ENSG00000173113	TRMT112	100	73.016	ENSPCIG00000008032	TRMT112	100	73.016	Phascolarctos_cinereus
ENSG00000173113	TRMT112	100	100.000	ENSPPYG00000025906	TRMT112	100	100.000	Pongo_abelii
ENSG00000173113	TRMT112	98	82.114	ENSPCAG00000010782	TRMT112	98	82.114	Procavia_capensis
ENSG00000173113	TRMT112	100	83.200	ENSPCOG00000027044	TRMT112	100	83.200	Propithecus_coquereli
ENSG00000173113	TRMT112	100	82.400	ENSPVAG00000017134	TRMT112	100	82.400	Pteropus_vampyrus
ENSG00000173113	TRMT112	100	80.800	ENSRNOG00000021132	Trmt112	100	80.800	Rattus_norvegicus
ENSG00000173113	TRMT112	100	98.765	ENSRBIG00000042875	-	100	98.400	Rhinopithecus_bieti
ENSG00000173113	TRMT112	100	99.200	ENSRBIG00000039623	-	100	99.200	Rhinopithecus_bieti
ENSG00000173113	TRMT112	95	83.117	ENSRBIG00000041110	-	94	78.151	Rhinopithecus_bieti
ENSG00000173113	TRMT112	100	99.200	ENSRROG00000044424	TRMT112	100	99.200	Rhinopithecus_roxellana
ENSG00000173113	TRMT112	100	94.400	ENSSBOG00000023130	-	100	94.400	Saimiri_boliviensis_boliviensis
ENSG00000173113	TRMT112	100	80.800	ENSSSCG00000013029	TRMT112	100	80.800	Sus_scrofa
ENSG00000173113	TRMT112	80	73.846	ENSTBEG00000006300	-	100	73.846	Tupaia_belangeri
ENSG00000173113	TRMT112	100	82.400	ENSTTRG00000010299	TRMT112	100	82.400	Tursiops_truncatus
ENSG00000173113	TRMT112	100	74.400	ENSUAMG00000018571	-	100	74.400	Ursus_americanus
ENSG00000173113	TRMT112	100	84.000	ENSUAMG00000015174	-	100	84.000	Ursus_americanus
ENSG00000173113	TRMT112	100	82.787	ENSUMAG00000002772	-	100	82.787	Ursus_maritimus
ENSG00000173113	TRMT112	100	73.600	ENSUMAG00000001654	-	100	73.600	Ursus_maritimus
ENSG00000173113	TRMT112	100	84.000	ENSVVUG00000029760	TRMT112	100	84.000	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	18539146.20123966.20308323.	IPI	Function
GO:0005654	nucleoplasm	25851604.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006415	translational termination	-	TAS	Process
GO:0008276	protein methyltransferase activity	18539146.	IDA	Function
GO:0016435	rRNA (guanine) methyltransferase activity	25851604.	IMP	Function
GO:0018364	peptidyl-glutamine methylation	21873635.	IBA	Process
GO:0018364	peptidyl-glutamine methylation	18539146.	IDA	Process
GO:0030488	tRNA methylation	21873635.	IBA	Process
GO:0031167	rRNA methylation	-	TAS	Process
GO:0032259	methylation	-	TAS	Process
GO:0032991	protein-containing complex	18539146.	IDA	Component
GO:0046982	protein heterodimerization activity	25851604.	IDA	Function
GO:0048471	perinuclear region of cytoplasm	25851604.	IDA	Component
GO:0070476	rRNA (guanine-N7)-methylation	21873635.	IBA	Process
GO:0070476	rRNA (guanine-N7)-methylation	25851604.	IMP	Process
GO:2000234	positive regulation of rRNA processing	25851604.	IMP	Process