EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000173193 (Gene tree)
Gene ID: 54625
Gene Symbol: PARP14
Alias: KIAA1268|pART8
Full Name: poly(ADP-ribose) polymerase family member 14
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 50,223 bases
Position: chr3:122,680,618-122,730,840
Accession: 29232
RBP type: canonical RBP
Summary: This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000418194	PARP	PF00644.20	7e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000474629	PARP14-202	7915	XM_011512928	ENSP00000418194	1801 (aa)	XP_011511230	Q460N5
ENST00000649945	PARP14-207	5411	-	ENSP00000497854	292 (aa)	-	-
ENST00000494811	PARP14-206	581	-	ENSP00000418535	185 (aa)	-	H7C4Y3
ENST00000475640	PARP14-204	850	-	-	- (aa)	-	-
ENST00000483611	PARP14-205	394	-	-	- (aa)	-	-
ENST00000460683	PARP14-201	8437	-	ENSP00000420649	1521 (aa)	-	H7C5R8
ENST00000474669	PARP14-203	5229	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000173193's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000173193	Hip	8.49458615775224E-5	17903296
ENSG00000173193	Neutrophils	2.217e-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000173193's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000173193	PARP14	98	31.753	ENSAPOG00000006513	si:ch211-219a4.3	96	33.879	Acanthochromis_polyacanthus
ENSG00000173193	PARP14	100	74.627	ENSAMEG00000004862	PARP14	99	70.378	Ailuropoda_melanoleuca
ENSG00000173193	PARP14	99	33.369	ENSACIG00000003944	si:ch211-219a4.3	94	52.475	Amphilophus_citrinellus
ENSG00000173193	PARP14	99	33.480	ENSACIG00000004115	si:ch211-219a4.3	97	38.144	Amphilophus_citrinellus
ENSG00000173193	PARP14	99	33.134	ENSACIG00000004252	si:ch211-219a4.3	100	46.552	Amphilophus_citrinellus
ENSG00000173193	PARP14	99	34.566	ENSAOCG00000012848	si:ch211-219a4.3	100	34.474	Amphiprion_ocellaris
ENSG00000173193	PARP14	99	34.673	ENSAPEG00000006205	si:ch211-219a4.3	100	34.580	Amphiprion_percula
ENSG00000173193	PARP14	51	31.940	ENSAPEG00000003728	-	99	32.107	Amphiprion_percula
ENSG00000173193	PARP14	61	30.095	ENSAPEG00000001687	-	95	48.469	Amphiprion_percula
ENSG00000173193	PARP14	99	34.355	ENSATEG00000010770	si:ch211-219a4.3	100	34.306	Anabas_testudineus
ENSG00000173193	PARP14	99	42.708	ENSAPLG00000010410	-	99	42.818	Anas_platyrhynchos
ENSG00000173193	PARP14	97	42.299	ENSAPLG00000010062	-	100	42.258	Anas_platyrhynchos
ENSG00000173193	PARP14	97	46.667	ENSACAG00000009769	-	99	42.251	Anolis_carolinensis
ENSG00000173193	PARP14	100	86.674	ENSANAG00000030799	PARP14	100	86.619	Aotus_nancymaae
ENSG00000173193	PARP14	99	34.686	ENSACLG00000005450	si:ch211-219a4.3	100	34.686	Astatotilapia_calliptera
ENSG00000173193	PARP14	53	45.417	ENSACLG00000005418	-	99	45.417	Astatotilapia_calliptera
ENSG00000173193	PARP14	55	37.712	ENSAMXG00000043329	-	99	37.712	Astyanax_mexicanus
ENSG00000173193	PARP14	55	40.845	ENSAMXG00000031852	-	99	40.845	Astyanax_mexicanus
ENSG00000173193	PARP14	97	73.333	ENSBTAG00000016656	PARP14	99	70.588	Bos_taurus
ENSG00000173193	PARP14	100	87.785	ENSCJAG00000007930	PARP14	100	87.562	Callithrix_jacchus
ENSG00000173193	PARP14	100	76.119	ENSCAFG00000011970	PARP14	99	68.184	Canis_familiaris
ENSG00000173193	PARP14	100	76.119	ENSCAFG00020005495	PARP14	99	68.278	Canis_lupus_dingo
ENSG00000173193	PARP14	100	69.900	ENSCHIG00000018391	PARP14	100	69.828	Capra_hircus
ENSG00000173193	PARP14	100	78.924	ENSTSYG00000005576	PARP14	100	78.869	Carlito_syrichta
ENSG00000173193	PARP14	97	63.375	ENSCAPG00000016922	PARP14	100	63.318	Cavia_aperea
ENSG00000173193	PARP14	98	61.892	ENSCPOG00000020020	PARP14	99	63.736	Cavia_porcellus
ENSG00000173193	PARP14	100	87.063	ENSCCAG00000028961	PARP14	100	87.007	Cebus_capucinus
ENSG00000173193	PARP14	100	92.060	ENSCATG00000033839	PARP14	100	92.004	Cercocebus_atys
ENSG00000173193	PARP14	100	69.857	ENSCLAG00000009862	PARP14	100	69.637	Chinchilla_lanigera
ENSG00000173193	PARP14	100	92.227	ENSCSAG00000007464	PARP14	100	92.171	Chlorocebus_sabaeus
ENSG00000173193	PARP14	88	71.655	ENSCHOG00000010569	PARP14	86	71.655	Choloepus_hoffmanni
ENSG00000173193	PARP14	99	46.407	ENSCPBG00000013908	-	99	46.247	Chrysemys_picta_bellii
ENSG00000173193	PARP14	99	45.875	ENSCPBG00000013912	-	99	45.650	Chrysemys_picta_bellii
ENSG00000173193	PARP14	100	91.949	ENSCANG00000040574	PARP14	100	92.060	Colobus_angolensis_palliatus
ENSG00000173193	PARP14	100	70.149	ENSCGRG00001006699	Parp14	100	64.856	Cricetulus_griseus_chok1gshd
ENSG00000173193	PARP14	100	70.149	ENSCGRG00000014558	Parp14	100	64.856	Cricetulus_griseus_crigri
ENSG00000173193	PARP14	95	32.063	ENSCSEG00000017936	si:ch211-219a4.3	99	41.148	Cynoglossus_semilaevis
ENSG00000173193	PARP14	99	33.821	ENSCVAG00000008369	si:ch211-219a4.3	100	33.659	Cyprinodon_variegatus
ENSG00000173193	PARP14	99	33.978	ENSDARG00000040445	si:ch211-219a4.3	99	38.655	Danio_rerio
ENSG00000173193	PARP14	100	75.714	ENSDNOG00000015400	PARP14	100	71.936	Dasypus_novemcinctus
ENSG00000173193	PARP14	100	70.000	ENSDORG00000000690	Parp14	100	68.240	Dipodomys_ordii
ENSG00000173193	PARP14	98	62.620	ENSETEG00000002790	PARP14	96	68.371	Echinops_telfairi
ENSG00000173193	PARP14	100	74.627	ENSEASG00005016553	PARP14	100	74.181	Equus_asinus_asinus
ENSG00000173193	PARP14	100	77.350	ENSECAG00000024988	PARP14	100	77.350	Equus_caballus
ENSG00000173193	PARP14	98	67.938	ENSEEUG00000002136	PARP14	100	69.475	Erinaceus_europaeus
ENSG00000173193	PARP14	99	40.704	ENSELUG00000009798	si:ch211-219a4.3	99	40.704	Esox_lucius
ENSG00000173193	PARP14	99	76.471	ENSFCAG00000000930	PARP14	99	73.056	Felis_catus
ENSG00000173193	PARP14	98	41.144	ENSFALG00000013545	-	100	41.222	Ficedula_albicollis
ENSG00000173193	PARP14	99	42.240	ENSFALG00000013541	-	96	42.091	Ficedula_albicollis
ENSG00000173193	PARP14	100	70.000	ENSFDAG00000008689	PARP14	100	69.791	Fukomys_damarensis
ENSG00000173193	PARP14	98	31.907	ENSFHEG00000007383	si:ch211-219a4.3	98	32.442	Fundulus_heteroclitus
ENSG00000173193	PARP14	95	30.890	ENSGMOG00000008501	-	99	34.304	Gadus_morhua
ENSG00000173193	PARP14	91	37.327	ENSGMOG00000009701	-	88	37.327	Gadus_morhua
ENSG00000173193	PARP14	55	37.654	ENSGMOG00000011231	-	99	41.880	Gadus_morhua
ENSG00000173193	PARP14	83	60.000	ENSGALG00000026422	-	99	42.025	Gallus_gallus
ENSG00000173193	PARP14	99	42.507	ENSGALG00000012072	-	99	42.400	Gallus_gallus
ENSG00000173193	PARP14	99	33.789	ENSGAFG00000009879	si:ch211-219a4.3	99	41.329	Gambusia_affinis
ENSG00000173193	PARP14	99	34.726	ENSGACG00000002353	si:ch211-219a4.3	97	51.515	Gasterosteus_aculeatus
ENSG00000173193	PARP14	56	32.264	ENSGACG00000018943	-	99	32.230	Gasterosteus_aculeatus
ENSG00000173193	PARP14	97	50.435	ENSGAGG00000017725	-	99	50.157	Gopherus_agassizii
ENSG00000173193	PARP14	98	44.664	ENSGAGG00000000808	-	100	46.695	Gopherus_agassizii
ENSG00000173193	PARP14	100	98.834	ENSGGOG00000001623	PARP14	100	98.834	Gorilla_gorilla
ENSG00000173193	PARP14	100	72.857	ENSHGLG00000001930	PARP14	100	71.484	Heterocephalus_glaber_female
ENSG00000173193	PARP14	100	69.551	ENSHGLG00100018459	PARP14	100	69.491	Heterocephalus_glaber_male
ENSG00000173193	PARP14	99	36.033	ENSIPUG00000003936	si:ch211-219a4.3	99	35.963	Ictalurus_punctatus
ENSG00000173193	PARP14	100	73.134	ENSSTOG00000019423	PARP14	100	74.086	Ictidomys_tridecemlineatus
ENSG00000173193	PARP14	99	34.363	ENSKMAG00000019118	si:ch211-219a4.3	100	34.451	Kryptolebias_marmoratus
ENSG00000173193	PARP14	50	48.058	ENSKMAG00000016827	-	97	48.058	Kryptolebias_marmoratus
ENSG00000173193	PARP14	97	32.477	ENSLBEG00000025830	si:ch211-219a4.3	100	34.532	Labrus_bergylta
ENSG00000173193	PARP14	100	40.142	ENSLACG00000012073	PARP14	100	40.142	Latimeria_chalumnae
ENSG00000173193	PARP14	99	39.442	ENSLOCG00000003430	si:ch211-219a4.3	99	39.333	Lepisosteus_oculatus
ENSG00000173193	PARP14	60	30.309	ENSLOCG00000000239	si:cabz01030277.1	99	30.309	Lepisosteus_oculatus
ENSG00000173193	PARP14	99	37.772	ENSLOCG00000003463	-	99	37.772	Lepisosteus_oculatus
ENSG00000173193	PARP14	96	67.738	ENSLAFG00000021607	PARP14	99	67.738	Loxodonta_africana
ENSG00000173193	PARP14	100	92.393	ENSMFAG00000038097	PARP14	100	92.338	Macaca_fascicularis
ENSG00000173193	PARP14	100	92.338	ENSMMUG00000022569	PARP14	100	92.282	Macaca_mulatta
ENSG00000173193	PARP14	100	92.338	ENSMNEG00000035861	PARP14	100	92.282	Macaca_nemestrina
ENSG00000173193	PARP14	100	92.060	ENSMLEG00000041852	PARP14	100	92.004	Mandrillus_leucophaeus
ENSG00000173193	PARP14	99	34.813	ENSMAMG00000012417	si:ch211-219a4.3	100	34.580	Mastacembelus_armatus
ENSG00000173193	PARP14	99	34.526	ENSMZEG00005016195	si:ch211-219a4.3	100	34.526	Maylandia_zebra
ENSG00000173193	PARP14	99	32.989	ENSMZEG00005025678	si:ch211-219a4.3	91	50.990	Maylandia_zebra
ENSG00000173193	PARP14	98	41.824	ENSMGAG00000012246	-	99	43.359	Meleagris_gallopavo
ENSG00000173193	PARP14	100	82.857	ENSMICG00000049225	PARP14	96	77.401	Microcebus_murinus
ENSG00000173193	PARP14	79	70.968	ENSMOCG00000021121	Parp14	94	70.968	Microtus_ochrogaster
ENSG00000173193	PARP14	99	50.139	ENSMODG00000018318	-	99	50.028	Monodelphis_domestica
ENSG00000173193	PARP14	99	52.857	ENSMODG00000018308	-	97	48.274	Monodelphis_domestica
ENSG00000173193	PARP14	100	68.657	MGP_CAROLIEiJ_G0020706	Parp14	100	63.326	Mus_caroli
ENSG00000173193	PARP14	100	68.657	ENSMUSG00000034422	Parp14	100	62.890	Mus_musculus
ENSG00000173193	PARP14	100	70.149	MGP_PahariEiJ_G0016409	Parp14	100	64.050	Mus_pahari
ENSG00000173193	PARP14	100	68.657	MGP_SPRETEiJ_G0021604	Parp14	100	63.123	Mus_spretus
ENSG00000173193	PARP14	100	70.149	ENSMPUG00000004629	PARP14	99	67.107	Mustela_putorius_furo
ENSG00000173193	PARP14	100	70.011	ENSMLUG00000023256	-	100	69.900	Myotis_lucifugus
ENSG00000173193	PARP14	92	68.023	ENSMLUG00000022755	-	100	69.450	Myotis_lucifugus
ENSG00000173193	PARP14	98	66.955	ENSMLUG00000008047	-	99	68.263	Myotis_lucifugus
ENSG00000173193	PARP14	100	69.623	ENSMLUG00000030765	-	100	69.512	Myotis_lucifugus
ENSG00000173193	PARP14	100	73.134	ENSNGAG00000024058	Parp14	100	63.115	Nannospalax_galili
ENSG00000173193	PARP14	98	95.527	ENSNLEG00000000311	PARP14	99	95.802	Nomascus_leucogenys
ENSG00000173193	PARP14	98	49.813	ENSMEUG00000003239	-	100	49.813	Notamacropus_eugenii
ENSG00000173193	PARP14	100	64.865	ENSOPRG00000013872	PARP14	82	69.308	Ochotona_princeps
ENSG00000173193	PARP14	100	73.134	ENSODEG00000008430	PARP14	100	67.239	Octodon_degus
ENSG00000173193	PARP14	94	37.823	ENSONIG00000004515	si:ch211-219a4.3	100	37.689	Oreochromis_niloticus
ENSG00000173193	PARP14	54	33.115	ENSONIG00000007870	-	99	33.868	Oreochromis_niloticus
ENSG00000173193	PARP14	100	71.831	ENSOCUG00000003418	PARP14	99	68.656	Oryctolagus_cuniculus
ENSG00000173193	PARP14	99	39.352	ENSORLG00015021971	si:ch211-219a4.3	93	52.792	Oryzias_latipes_hsok
ENSG00000173193	PARP14	55	31.003	ENSOMEG00000022143	-	96	31.003	Oryzias_melastigma
ENSG00000173193	PARP14	98	31.651	ENSOMEG00000019715	si:ch211-219a4.3	92	53.030	Oryzias_melastigma
ENSG00000173193	PARP14	100	70.000	ENSOGAG00000012454	PARP14	85	67.368	Otolemur_garnettii
ENSG00000173193	PARP14	100	70.177	ENSOARG00000020160	PARP14	100	70.105	Ovis_aries
ENSG00000173193	PARP14	100	98.778	ENSPPAG00000039852	PARP14	100	98.778	Pan_paniscus
ENSG00000173193	PARP14	95	79.856	ENSPPRG00000002799	PARP14	99	73.444	Panthera_pardus
ENSG00000173193	PARP14	95	79.856	ENSPTIG00000011462	PARP14	99	73.444	Panthera_tigris_altaica
ENSG00000173193	PARP14	100	98.834	ENSPTRG00000015297	PARP14	100	98.834	Pan_troglodytes
ENSG00000173193	PARP14	100	91.838	ENSPANG00000000522	PARP14	100	91.782	Papio_anubis
ENSG00000173193	PARP14	55	41.834	ENSPKIG00000004027	-	100	41.797	Paramormyrops_kingsleyae
ENSG00000173193	PARP14	99	46.510	ENSPSIG00000003516	PARP14	99	46.510	Pelodiscus_sinensis
ENSG00000173193	PARP14	100	68.657	ENSPEMG00000008286	Parp14	100	64.638	Peromyscus_maniculatus_bairdii
ENSG00000173193	PARP14	57	32.867	ENSPMAG00000009649	-	99	32.867	Petromyzon_marinus
ENSG00000173193	PARP14	89	38.058	ENSPMAG00000001173	-	85	39.385	Petromyzon_marinus
ENSG00000173193	PARP14	75	30.947	ENSPMAG00000002848	-	99	31.069	Petromyzon_marinus
ENSG00000173193	PARP14	63	30.789	ENSPFOG00000000012	-	99	32.780	Poecilia_formosa
ENSG00000173193	PARP14	99	34.670	ENSPFOG00000016743	si:ch211-219a4.3	99	39.949	Poecilia_formosa
ENSG00000173193	PARP14	99	34.150	ENSPLAG00000023145	si:ch211-219a4.3	100	34.188	Poecilia_latipinna
ENSG00000173193	PARP14	99	34.382	ENSPMEG00000000483	si:ch211-219a4.3	100	34.507	Poecilia_mexicana
ENSG00000173193	PARP14	63	30.724	ENSPMEG00000004328	-	88	49.495	Poecilia_mexicana
ENSG00000173193	PARP14	52	53.333	ENSPREG00000019182	-	88	53.333	Poecilia_reticulata
ENSG00000173193	PARP14	92	96.724	ENSPPYG00000013479	PARP14	100	97.416	Pongo_abelii
ENSG00000173193	PARP14	85	77.922	ENSPCAG00000005805	-	73	77.922	Procavia_capensis
ENSG00000173193	PARP14	100	85.714	ENSPCOG00000007904	PARP14	100	78.679	Propithecus_coquereli
ENSG00000173193	PARP14	92	72.091	ENSPVAG00000012722	PARP14	99	71.609	Pteropus_vampyrus
ENSG00000173193	PARP14	99	34.098	ENSPNYG00000001481	si:ch211-219a4.3	99	34.080	Pundamilia_nyererei
ENSG00000173193	PARP14	55	39.691	ENSPNYG00000013937	-	100	50.990	Pundamilia_nyererei
ENSG00000173193	PARP14	98	33.825	ENSPNAG00000028188	si:ch211-219a4.3	99	36.277	Pygocentrus_nattereri
ENSG00000173193	PARP14	100	71.642	ENSRNOG00000023334	Parp14	100	63.339	Rattus_norvegicus
ENSG00000173193	PARP14	100	92.115	ENSRBIG00000042403	PARP14	100	92.060	Rhinopithecus_bieti
ENSG00000173193	PARP14	100	92.227	ENSRROG00000042264	PARP14	100	92.171	Rhinopithecus_roxellana
ENSG00000173193	PARP14	100	86.880	ENSSBOG00000032798	PARP14	100	86.880	Saimiri_boliviensis_boliviensis
ENSG00000173193	PARP14	100	52.470	ENSSHAG00000002478	PARP14	100	52.446	Sarcophilus_harrisii
ENSG00000173193	PARP14	98	33.810	ENSSFOG00015022852	si:ch211-219a4.3	99	36.100	Scleropages_formosus
ENSG00000173193	PARP14	99	40.199	ENSSFOG00015001605	-	88	56.579	Scleropages_formosus
ENSG00000173193	PARP14	99	33.513	ENSSMAG00000003869	si:ch211-219a4.3	100	33.405	Scophthalmus_maximus
ENSG00000173193	PARP14	52	31.695	ENSSDUG00000007576	-	99	32.209	Seriola_dumerili
ENSG00000173193	PARP14	99	35.316	ENSSDUG00000009289	si:ch211-219a4.3	100	35.208	Seriola_dumerili
ENSG00000173193	PARP14	65	30.424	ENSSDUG00000007589	-	91	30.346	Seriola_dumerili
ENSG00000173193	PARP14	99	35.233	ENSSLDG00000020946	si:ch211-219a4.3	100	35.125	Seriola_lalandi_dorsalis
ENSG00000173193	PARP14	91	72.318	ENSSARG00000011299	PARP14	95	72.318	Sorex_araneus
ENSG00000173193	PARP14	98	44.207	ENSSPUG00000016288	-	97	46.204	Sphenodon_punctatus
ENSG00000173193	PARP14	98	44.247	ENSSPUG00000016301	-	100	46.302	Sphenodon_punctatus
ENSG00000173193	PARP14	98	33.205	ENSSPAG00000009605	si:ch211-219a4.3	100	33.005	Stegastes_partitus
ENSG00000173193	PARP14	100	69.884	ENSSSCG00000011874	PARP14	100	69.884	Sus_scrofa
ENSG00000173193	PARP14	90	40.387	ENSTGUG00000003925	PARP14	100	42.383	Taeniopygia_guttata
ENSG00000173193	PARP14	50	39.260	ENSTRUG00000004579	-	94	52.713	Takifugu_rubripes
ENSG00000173193	PARP14	100	73.134	ENSUMAG00000025217	PARP14	99	69.912	Ursus_maritimus
ENSG00000173193	PARP14	82	75.000	ENSVPAG00000002158	PARP14	84	75.000	Vicugna_pacos
ENSG00000173193	PARP14	100	77.612	ENSVVUG00000022533	PARP14	99	73.333	Vulpes_vulpes
ENSG00000173193	PARP14	100	39.444	ENSXETG00000023399	parp14.2	100	39.444	Xenopus_tropicalis
ENSG00000173193	PARP14	90	36.846	ENSXETG00000023401	-	99	39.896	Xenopus_tropicalis
ENSG00000173193	PARP14	51	61.236	ENSXETG00000023400	-	96	61.236	Xenopus_tropicalis
ENSG00000173193	PARP14	98	33.776	ENSXMAG00000026293	-	99	33.960	Xiphophorus_maculatus
ENSG00000173193	PARP14	99	34.349	ENSXMAG00000026958	si:ch211-219a4.3	100	34.530	Xiphophorus_maculatus
ENSG00000173193	PARP14	99	34.632	ENSXMAG00000007367	si:ch211-219a4.3	100	34.578	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003950	NAD+ ADP-ribosyltransferase activity	27796300.	IDA	Function
GO:0005515	protein binding	23473667.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	27796300.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006471	protein ADP-ribosylation	27796300.	IDA	Process
GO:0010629	negative regulation of gene expression	27796300.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0019899	enzyme binding	27796300.	IPI	Function
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	27796300.	IMP	Process
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	27796300.	IMP	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	27796300.	IMP	Process
GO:1902216	positive regulation of interleukin-4-mediated signaling pathway	27796300.	IMP	Process
GO:1990404	protein ADP-ribosylase activity	18851833.25043379.	IDA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24886089	DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells.	Mol Cancer	2014 May 27	Bachmann SB	doi: 10.1186/1476-4598-13-125.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr3	122699812	Missense_Mutation	novel	D420N	0.15
BLCA	chr3	122714364	Missense_Mutation	novel	S1312C	0.08
BLCA	chr3	122685239	Missense_Mutation	novel	G81A	0.2
BLCA	chr3	122718396	Missense_Mutation	rs749431885	K1415N	0.43
BLCA	chr3	122728559	Missense_Mutation	NA	Q1790E	0.13	PARP
BLCA	chr3	122699536	Missense_Mutation	novel	L328V	0.09
BLCA	chr3	122718918	Missense_Mutation	novel	K1589N	0.21
BLCA	chr3	122680943	Silent	NA	P20P	0.32
BLCA	chr3	122701355	Missense_Mutation	NA	V934G	0.15
BLCA	chr3	122700741	Missense_Mutation	NA	D729E	0.11
BLCA	chr3	122700216	Silent	novel	F554F	0.14
BLCA	chr3	122699862	Silent	novel	A436A	0.16
BLCA	chr3	122714308	Missense_Mutation	novel	L1293F	0.23
BLCA	chr3	122718706	Nonsense_Mutation	rs776658320	R1519*	0.16
BLCA	chr3	122714264	Nonsense_Mutation	novel	Q1279*	0.6
BLCA	chr3	122718946	Frame_Shift_Ins	novel	*T1599Nfs7**	0.1
BLCA	chr3	122699491	Nonsense_Mutation	novel	K313*	0.07
BLCA	chr3	122681054	Missense_Mutation	novel	F57L	0.55
BLCA	chr3	122701096	Missense_Mutation	novel	D848N	0.09
BLCA	chr3	122727950	Nonsense_Mutation	NA	R1694*	0.42	PARP
BLCA	chr3	122720439	Intron	novel		0.4
BLCA	chr3	122718924	Silent	NA	H1591H	0.17
BLCA	chr3	122713502	Missense_Mutation	novel	S1233F	0.27
BRCA	chr3	122714264	Missense_Mutation	novel	Q1279E	0.09
BRCA	chr3	122701132	Missense_Mutation	NA	L860V	0.48
BRCA	chr3	122695590	Missense_Mutation	NA	G255R	0.16
BRCA	chr3	122681025	Missense_Mutation	NA	P48S	0.33
BRCA	chr3	122728448	Missense_Mutation	rs773230901	H1753Y	0.28	PARP
BRCA	chr3	122700135	Silent	NA	K527K	0.27
BRCA	chr3	122703834	Silent	rs753057524	L1058L	0.1
BRCA	chr3	122728403	Missense_Mutation	NA	V1738M	0.13	PARP
BRCA	chr3	122701219	Missense_Mutation	novel	E889K	0.14
BRCA	chr3	122695580	Silent	novel	P251P	0.14
BRCA	chr3	122720456	Intron	novel		0.07
BRCA	chr3	122718547	Missense_Mutation	novel	D1466H	0.09
BRCA	chr3	122701027	Missense_Mutation	NA	E825K	0.15
BRCA	chr3	122700511	Nonsense_Mutation	NA	E653*	0.21
BRCA	chr3	122718804	Missense_Mutation	NA	M1551I	0.17
BRCA	chr3	122720526	Intron	novel		0.44
CESC	chr3	122700353	Missense_Mutation	novel	R600H	0.08
CESC	chr3	122700992	Missense_Mutation	novel	R813Q	0.32
CESC	chr3	122730642	3'UTR	novel		0.1
CESC	chr3	122730741	3'UTR	novel		0.13
CESC	chr3	122703788	Missense_Mutation	novel	R1043K	0.18
CESC	chr3	122713544	Nonsense_Mutation	NA	S1247*	0.24
CESC	chr3	122699419	Missense_Mutation	rs763101562	D289N	0.23
CESC	chr3	122718835	Missense_Mutation	novel	E1562Q	0.28
CESC	chr3	122728481	Missense_Mutation	rs766000674	Q1764E	0.09	PARP
CESC	chr3	122720329	Missense_Mutation	rs772798978	E1628Q	0.3	PARP
CESC	chr3	122699719	Missense_Mutation	novel	T389A	0.44
CESC	chr3	122701061	Missense_Mutation	rs764823251	A836V	0.42
CESC	chr3	122704682	Missense_Mutation	NA	K1158N	0.38
CESC	chr3	122718940	Missense_Mutation	rs765698403	R1597C	0.22
CESC	chr3	122713556	Missense_Mutation	NA	S1251L	0.24
CESC	chr3	122699947	Nonsense_Mutation	NA	Q465*	0.15
CESC	chr3	122728470	Nonsense_Mutation	novel	S1760*	0.16	PARP
COAD	chr3	122687104	Nonsense_Mutation	novel	K116*	0.19
COAD	chr3	122718388	Frame_Shift_Ins	NA	*N1416Efs19**	0.2
COAD	chr3	122699920	Missense_Mutation	NA	T456S	0.11
COAD	chr3	122701264	Missense_Mutation	novel	S904G	0.23
COAD	chr3	122728396	Silent	novel	R1735R	0.38
COAD	chr3	122680937	Frame_Shift_Del	novel	*P20Rfs4**	0.22
COAD	chr3	122701183	Missense_Mutation	rs752297915	V877M	0.43
COAD	chr3	122700306	Silent	NA	A584A	0.38
COAD	chr3	122680888	Missense_Mutation	novel	A2V	0.44
COAD	chr3	122699752	Missense_Mutation	novel	V400F	0.27
COAD	chr3	122718871	Missense_Mutation	NA	R1574W	0.32
COAD	chr3	122714340	Missense_Mutation	NA	G1304E	0.3
COAD	chr3	122700750	Silent	rs759759862	K732K	0.14
COAD	chr3	122701062	Silent	rs538044529	A836A	0.35
COAD	chr3	122699793	Frame_Shift_Del	NA	*N415Mfs3**	0.05
COAD	chr3	122700120	Silent	novel	C522C	0.1
COAD	chr3	122700351	Silent	NA	K599K	0.29
COAD	chr3	122720264	Missense_Mutation	NA	P1606H	0.2
COAD	chr3	122703847	Missense_Mutation	rs751235147	D1063N	0.35
COAD	chr3	122720285	Missense_Mutation	novel	K1613R	0.05
COAD	chr3	122720400	Intron	novel		0.15
COAD	chr3	122720390	Splice_Site	novel	X1647_splice	0.16
COAD	chr3	122728619	3'UTR	novel		0.27
COAD	chr3	122680946	Missense_Mutation	NA	K21N	0.23
COAD	chr3	122699414	Missense_Mutation	NA	K287R	0.21
COAD	chr3	122703773	Missense_Mutation	novel	D1038A	0.28
COAD	chr3	122701388	Missense_Mutation	NA	F945S	0.25
COAD	chr3	122718804	Missense_Mutation	novel	M1551I	0.23
COAD	chr3	122701420	Missense_Mutation	novel	E956K	0.32
COAD	chr3	122718840	Missense_Mutation	NA	K1563N	0.32
COAD	chr3	122727895	Missense_Mutation	novel	M1675I	0.1	PARP
COAD	chr3	122728766	3'UTR	novel		0.62
COAD	chr3	122685224	Missense_Mutation	NA	V76A	0.2
COAD	chr3	122695646	Silent	NA	E273E	0.28
COAD	chr3	122718751	Missense_Mutation	novel	F1534L	0.08
COAD	chr3	122718706	Nonsense_Mutation	rs776658320	R1519*	0.2
COAD	chr3	122701517	Missense_Mutation	rs771490414	P988L	0.47
COAD	chr3	122728439	Missense_Mutation	NA	H1750Y	0.36	PARP
COAD	chr3	122703881	Missense_Mutation	NA	G1074A	0.26
ESCA	chr3	122728528	Silent	novel	H1779H	0.46
GBM	chr3	122701073	Missense_Mutation	novel	A840V	0.23
GBM	chr3	122718706	Nonsense_Mutation	rs776658320	R1519*	0.14
GBM	chr3	122727943	Silent	novel	H1691H	0.14
GBM	chr3	122728722	3'UTR	novel		0.2
HNSC	chr3	122692510	Missense_Mutation	novel	D189H	0.18
HNSC	chr3	122718696	Missense_Mutation	novel	I1515M	0.07
HNSC	chr3	122701517	Missense_Mutation	rs771490414	P988L	0.23
HNSC	chr3	122718647	Missense_Mutation	novel	G1499E	0.17
HNSC	chr3	122718840	Frame_Shift_Ins	NA	*T1566Nfs3**	0.16
HNSC	chr3	122713928	Nonsense_Mutation	novel	Q1276*	0.14
HNSC	chr3	122727910	Silent	novel	L1680L	0.14
HNSC	chr3	122720417	Intron	novel		0.14
HNSC	chr3	122720418	Intron	novel		0.14
HNSC	chr3	122701590	Silent	novel	G1012G	0.24
HNSC	chr3	122704612	Missense_Mutation	novel	G1135E	0.19
HNSC	chr3	122692459	Missense_Mutation	novel	I172V	0.16
HNSC	chr3	122728452	Missense_Mutation	novel	S1754L	0.2	PARP
HNSC	chr3	122701444	Missense_Mutation	novel	E964K	0.2
HNSC	chr3	122703956	Frame_Shift_Del	novel	*N1099Ifs17**	0.2
HNSC	chr3	122699947	Missense_Mutation	novel	Q465K	0.52
KICH	chr3	122701182	Silent	rs375197249	H876H	0.48
KIRC	chr3	122699793	Silent	NA	I413I	0.22
KIRC	chr3	122718699	Missense_Mutation	NA	K1516N	0.35
KIRC	chr3	122728580	Missense_Mutation	NA	I1797L	0.31	PARP
KIRC	chr3	122714373	Missense_Mutation	NA	L1315S	0.46
KIRC	chr3	122695616	Frame_Shift_Del	novel	*P265Lfs7**	0.33
KIRC	chr3	122700811	Frame_Shift_Ins	novel	*F753Sfs5**	0.07
KIRC	chr3	122700813	In_Frame_Ins	novel	F753_F754insSI	0.06
KIRP	chr3	122695505	Silent	NA	V226V	0.2
KIRP	chr3	122718849	Silent	rs377210300	T1566T	0.27
KIRP	chr3	122718853	Missense_Mutation	novel	D1568N	0.16
KIRP	chr3	122718854	Missense_Mutation	rs762330792	D1568V	0.16
KIRP	chr3	122718146	Nonsense_Mutation	NA	S1359*	0.56
LGG	chr3	122718822	Missense_Mutation	novel	E1557D	0.08
LGG	chr3	122728340	Missense_Mutation	novel	V1717I	0.4	PARP
LIHC	chr3	122699838	Silent	NA	T428T	0.22
LIHC	chr3	122728500	Missense_Mutation	novel	Y1770C	0.43	PARP
LUAD	chr3	122727944	Missense_Mutation	NA	V1692F	0.36	PARP
LUAD	chr3	122700775	Missense_Mutation	NA	K741E	0.31
LUAD	chr3	122718393	Missense_Mutation	NA	K1414N	0.25
LUAD	chr3	122718947	Missense_Mutation	rs200872488	T1599M	0.24
LUAD	chr3	122699908	In_Frame_Ins	novel	L452delinsCCGSI	0.09
LUAD	chr3	122699869	Missense_Mutation	NA	S439A	0.34
LUAD	chr3	122713574	Splice_Site	NA	X1257_splice	0.31
LUAD	chr3	122699936	Missense_Mutation	NA	K461R	0.2
LUAD	chr3	122701454	Missense_Mutation	NA	V967D	0.18
LUAD	chr3	122718525	Frame_Shift_Ins	novel	*S1459Kfs2**	0.14
LUAD	chr3	122727946	Silent	NA	V1692V	0.67
LUAD	chr3	122727956	Missense_Mutation	NA	G1696S	0.3	PARP
LUAD	chr3	122718729	Silent	NA	S1526S	0.28
LUAD	chr3	122703936	Silent	NA	V1092V	0.46
LUAD	chr3	122720445	Intron	novel		0.47
LUSC	chr3	122701332	Silent	novel	F926F	0.14
LUSC	chr3	122720464	Intron	NA		0.33
LUSC	chr3	122680925	Silent	NA	S14S	0.47
LUSC	chr3	122718430	Frame_Shift_Del	novel	*A1427Gfs4**	0.17
LUSC	chr3	122718582	Missense_Mutation	NA	E1477D	0.6
LUSC	chr3	122701469	Missense_Mutation	novel	E972A	0.16
LUSC	chr3	122700943	Missense_Mutation	novel	V797F	0.15
LUSC	chr3	122692329	Silent	NA	L128L	0.16
LUSC	chr3	122718624	Missense_Mutation	novel	K1491N	0.17
LUSC	chr3	122728716	3'UTR	novel		0.21
LUSC	chr3	122692533	Silent	novel	Q196Q	0.32
LUSC	chr3	122700914	Missense_Mutation	rs774915593	P787L	0.06
LUSC	chr3	122718089	Missense_Mutation	novel	P1340L	0.21
LUSC	chr3	122718089	Missense_Mutation	novel	P1340Q	0.28
OV	chr3	122718741	Nonsense_Mutation	novel	C1530*	0.04
OV	chr3	122714358	Missense_Mutation	novel	S1310L	0.18
OV	chr3	122720320	Missense_Mutation	novel	S1625G	0.07
OV	chr3	122699948	Missense_Mutation	novel	Q465R	0.09
OV	chr3	122701442	Missense_Mutation	novel	S963F	0.1
OV	chr3	122700172	Missense_Mutation	NA	P540T	0.46
OV	chr3	122699865	Silent	novel	G437G	0.04
OV	chr3	122728798	3'UTR	novel		0.07
OV	chr3	122703885	Silent	NA	T1075T	0.19
OV	chr3	122718186	Silent	rs201050912	L1372L	0.38
OV	chr3	122728577	Missense_Mutation	novel		0.17
OV	chr3	122700295	Missense_Mutation	novel	S581T	0.11
OV	chr3	122699428	Missense_Mutation	NA	K292E	0.27
PAAD	chr3	122687088	Silent	novel	K110K	0.1
PAAD	chr3	122692481	Missense_Mutation	novel	D179A	0.23
PAAD	chr3	122701227	Silent	rs369759529	P891P	0.17
PAAD	chr3	122703920	Missense_Mutation	rs771242017	R1087H	0.2
PAAD	chr3	122714391	Missense_Mutation	novel	K1321T	0.14
PAAD	chr3	122727876	Missense_Mutation	novel	A1669V	0.19	PARP
PCPG	chr3	122700125	Frame_Shift_Del	novel	*I524Tfs17**	0.11
PRAD	chr3	122699980	Missense_Mutation	NA	G476S	0.16
PRAD	chr3	122714365	Silent	novel	S1312S	0.41
PRAD	chr3	122728550	Missense_Mutation	NA	Y1787D	0.29	PARP
READ	chr3	122701025	Missense_Mutation	novel	N824S	0.08
READ	chr3	122727888	Missense_Mutation	NA	Q1673R	0.41	PARP
READ	chr3	122727934	Silent	rs766941855	S1688S	0.24
READ	chr3	122718560	Missense_Mutation	NA	K1470R	0.31
READ	chr3	122700429	Silent	NA	Q625Q	0.33
READ	chr3	122685286	Missense_Mutation	NA	D97Y	0.38
READ	chr3	122692312	Nonsense_Mutation	NA	E123*	0.33
READ	chr3	122699413	Missense_Mutation	NA	K287Q	0.44
READ	chr3	122699798	Missense_Mutation	NA	N415T	0.38
READ	chr3	122700390	Missense_Mutation	NA	K612N	0.39
READ	chr3	122718940	Missense_Mutation	rs765698403	R1597C	0.31
READ	chr3	122700373	Missense_Mutation	NA	E607K	0.2
READ	chr3	122703772	Missense_Mutation	novel	D1038Y	0.1
READ	chr3	122703978	Missense_Mutation	NA	K1106N	0.15
READ	chr3	122704661	Missense_Mutation	novel	E1151D	0.08
READ	chr3	122727951	Missense_Mutation	rs748490431	R1694Q	0.32	PARP
SARC	chr3	122703893	Missense_Mutation	novel	K1078T	0.23
SARC	chr3	122718484	Missense_Mutation	novel	W1445R	0.38
SARC	chr3	122718143	Missense_Mutation	novel	G1358A	0.06
SKCM	chr3	122687111	Missense_Mutation	NA	P118L	0.31
SKCM	chr3	122727901	Missense_Mutation	novel	E1677D	0.14	PARP
SKCM	chr3	122701019	Missense_Mutation	NA	A822G	0.14
SKCM	chr3	122700644	Missense_Mutation	NA	I697K	0.41
SKCM	chr3	122701204	Missense_Mutation	NA	R884C	0.26
SKCM	chr3	122718943	Missense_Mutation	NA	L1598F	0.14
SKCM	chr3	122700112	Missense_Mutation	rs765486506	A520T	0.33
SKCM	chr3	122718389	Frame_Shift_Del	NA	*K1415Rfs35**	0.12
SKCM	chr3	122718604	Missense_Mutation	novel	N1485Y	0.35
SKCM	chr3	122695578	Missense_Mutation	NA	P251S	0.21
SKCM	chr3	122695489	Missense_Mutation	NA	P221L	0.56
SKCM	chr3	122685285	Silent	rs377745953	I96I	0.24
SKCM	chr3	122718385	Missense_Mutation	rs200701085	P1412S	0.12
SKCM	chr3	122713515	Silent	rs773729810	T1237T	0.88
SKCM	chr3	122703810	Silent	NA	L1050L	0.42
SKCM	chr3	122699516	Missense_Mutation	NA	P321L	0.37
SKCM	chr3	122727815	Missense_Mutation	novel	E1649K	0.25	PARP
SKCM	chr3	122681054	Silent	NA	F57F	0.32
SKCM	chr3	122699712	Silent	NA	D386D	0.15
SKCM	chr3	122692388	Missense_Mutation	rs772978257	S148F	0.1
SKCM	chr3	122692389	Silent	novel	S148S	0.1
SKCM	chr3	122695620	Missense_Mutation	NA	P265S	0.33
SKCM	chr3	122695620	Missense_Mutation	NA	P265S	0.39
SKCM	chr3	122699548	Missense_Mutation	novel	K332E	0.09
SKCM	chr3	122685202	Missense_Mutation	NA	E69K	0.58
SKCM	chr3	122700803	Missense_Mutation	NA	A750G	0.46
SKCM	chr3	122701520	Missense_Mutation	novel	P989L	0.39
SKCM	chr3	122714404	Silent	novel	S1325S	0.38
STAD	chr3	122695651	Missense_Mutation	NA	F275S	0.1
STAD	chr3	122703829	Missense_Mutation	NA	E1057Q	0.23
STAD	chr3	122728632	3'UTR	novel		0.25
STAD	chr3	122701237	Missense_Mutation	novel	Y895H	0.28
STAD	chr3	122714385	Frame_Shift_Del	NA	*N1322Lfs20**	0.25
STAD	chr3	122699419	Missense_Mutation	rs763101562	D289N	0.32
STAD	chr3	122699784	Missense_Mutation	NA	W410C	0.32
STAD	chr3	122700353	Missense_Mutation	novel	R600H	0.35
STAD	chr3	122718617	Missense_Mutation	NA	D1489G	0.09
STAD	chr3	122681017	Missense_Mutation	NA	R45H	0.55
STAD	chr3	122728585	Silent	rs746543829	T1798T	0.05
STAD	chr3	122701248	Missense_Mutation	novel	R898S	0.28
STAD	chr3	122700935	Missense_Mutation	rs755795510	S794F	0.06
STAD	chr3	122699417	Missense_Mutation	NA	L288P	0.55
STAD	chr3	122699930	Missense_Mutation	NA	K459T	0.25
STAD	chr3	122718497	Missense_Mutation	NA	L1449P	0.26
STAD	chr3	122699793	Frame_Shift_Del	NA	*N415Mfs3**	0.17
STAD	chr3	122704591	Missense_Mutation	novel	A1128V	0.17
STAD	chr3	122699960	Frame_Shift_Del	novel	M471*	0.27
STAD	chr3	122714385	Frame_Shift_Del	rs758945932	*N1322Ifs26**	0.38
STAD	chr3	122700381	Silent	NA	L609L	0.5
STAD	chr3	122718620	Missense_Mutation	NA	H1490R	0.1
STAD	chr3	122701279	Missense_Mutation	rs761873665	E909K	0.33
STAD	chr3	122700421	In_Frame_Del	novel	K624del	0.23
STAD	chr3	122718877	Missense_Mutation	NA	Y1576H	0.24
STAD	chr3	122699604	Silent	novel	R350R	0.05
STAD	chr3	122699793	Frame_Shift_Del	NA	*N415Mfs3**	0.32
STAD	chr3	122701062	Silent	rs538044529	A836A	0.47
TGCT	chr3	122701568	Missense_Mutation	novel	K1005R	0.18
THCA	chr3	122718744	Missense_Mutation	NA	I1531M	0.04
UCEC	chr3	122692371	Missense_Mutation	NA	E142D	0.34
UCEC	chr3	122718203	Missense_Mutation	NA	V1378A	0.31
UCEC	chr3	122700211	Nonsense_Mutation	NA	E553*	0.32
UCEC	chr3	122700546	Silent	rs534086113	F664F	0.38
UCEC	chr3	122718221	Missense_Mutation	NA	K1384R	0.35
UCEC	chr3	122714418	Missense_Mutation	rs777651913	A1330V	0.26
UCEC	chr3	122728454	Silent	novel	L1755L	0.43
UCEC	chr3	122701263	Silent	novel	L903L	0.22
UCEC	chr3	122703769	Missense_Mutation	novel	L1037V	0.46
UCEC	chr3	122728385	Missense_Mutation	novel	A1732T	0.31	PARP
UCEC	chr3	122685285	Silent	rs377745953	I96I	0.26
UCEC	chr3	122699419	Missense_Mutation	rs763101562	D289N	0.13
UCEC	chr3	122718840	Missense_Mutation	NA	K1563N	0.28
UCEC	chr3	122695596	Missense_Mutation	novel	R257G	0.21
UCEC	chr3	122728347	Missense_Mutation	novel	A1719V	0.35	PARP
UCEC	chr3	122703925	Missense_Mutation	novel	V1089M	0.42
UCEC	chr3	122714293	Silent	rs777759583	T1288T	0.44
UCEC	chr3	122699690	Missense_Mutation	NA	R379I	0.47
UCEC	chr3	122699793	Frame_Shift_Del	NA	*N415Mfs3**	0.4
UCEC	chr3	122704599	Missense_Mutation	novel	A1131S	0.44
UCEC	chr3	122718918	Missense_Mutation	novel	K1589N	0.32
UCEC	chr3	122720926	Intron	novel		0.44
UCEC	chr3	122692406	Missense_Mutation	novel	E154G	0.37
UCEC	chr3	122718388	Frame_Shift_Ins	NA	*N1416Efs19**	0.39
UCEC	chr3	122728474	Missense_Mutation	novel	K1761N	0.38	PARP
UCEC	chr3	122699540	Missense_Mutation	NA	P329L	0.18
UCEC	chr3	122728514	Missense_Mutation	NA	D1775Y	0.26	PARP
UCEC	chr3	122701518	Silent	rs760556993	P988P	0.35
UCEC	chr3	122718444	Silent	novel	V1431V	0.36
UCEC	chr3	122718388	Frame_Shift_Ins	NA	*N1416Efs19**	0.48
UCEC	chr3	122704707	Missense_Mutation	rs188219681	V1167I	0.42
UCEC	chr3	122713886	Missense_Mutation	novel	I1262L	0.42
UCEC	chr3	122714410	Silent	novel	C1327C	0.07
UCEC	chr3	122728666	3'UTR	novel		0.5
UCEC	chr3	122700145	Missense_Mutation	novel	M531V	0.17
UCEC	chr3	122720502	Intron	novel		0.53
UCEC	chr3	122720654	Intron	novel		0.38
UCEC	chr3	122680980	Missense_Mutation	novel	S33G	0.46
UCEC	chr3	122703743	Missense_Mutation	novel	T1028I	0.33
UCEC	chr3	122718408	Silent	novel	V1419V	0.3
UCEC	chr3	122720898	Intron	novel		0.29
UCEC	chr3	122685188	Missense_Mutation	rs763758133	R64Q	0.4
UCEC	chr3	122703744	Splice_Region	rs201071811	T1028T	0.36
UCEC	chr3	122704641	Missense_Mutation	novel	A1145T	0.31
UCEC	chr3	122730736	3'UTR	rs184617612		0.3
UCEC	chr3	122718383	Missense_Mutation	NA	S1411C	0.12
UCEC	chr3	122687093	Missense_Mutation	novel	K112R	0.32
UCEC	chr3	122714277	Missense_Mutation	novel	N1283S	0.09
UCEC	chr3	122718396	Missense_Mutation	rs749431885	K1415N	0.37
UCEC	chr3	122692343	Missense_Mutation	novel	G133E	0.45
UCEC	chr3	122699927	Frame_Shift_Del	novel	*I460Lfs8**	0.33
UCEC	chr3	122699697	Missense_Mutation	novel	K381N	0.58
UCEC	chr3	122700211	Nonsense_Mutation	NA	E553*	0.4
UCEC	chr3	122701062	Silent	rs538044529	A836A	0.42
UCEC	chr3	122700244	Missense_Mutation	novel	I564L	0.43
UCEC	chr3	122727951	Missense_Mutation	rs748490431	R1694Q	0.39	PARP
UCEC	chr3	122681064	Nonsense_Mutation	novel	E61*	0.4
UCEC	chr3	122727859	Frame_Shift_Ins	novel	*T1666Nfs12**	0.49	PARP
UCEC	chr3	122695461	Missense_Mutation	NA	H212Y	0.22
UCEC	chr3	122700331	Missense_Mutation	NA	L593F	0.45
UCEC	chr3	122701303	Missense_Mutation	NA	A917S	0.19
UCEC	chr3	122718840	Frame_Shift_Ins	NA	*T1566Nfs3**	0.45
UCEC	chr3	122714380	Silent	novel	E1317E	0.34
UCEC	chr3	122720296	Missense_Mutation	novel	F1617V	0.36
UCEC	chr3	122727836	Missense_Mutation	novel	L1656I	0.29	PARP
UCEC	chr3	122718751	Missense_Mutation	novel	F1534L	0.29
UCEC	chr3	122718896	Missense_Mutation	novel	T1582I	0.34
UCEC	chr3	122700340	In_Frame_Ins	novel	L596delinsWI	0.11
UCEC	chr3	122700341	Nonsense_Mutation	novel	L596*	0.11
UCEC	chr3	122685228	Nonsense_Mutation	novel	W77*	0.24
UCEC	chr3	122700255	Silent	novel	L567L	0.11
UCEC	chr3	122701279	Missense_Mutation	rs761873665	E909K	0.15
UCEC	chr3	122701598	Missense_Mutation	novel	Q1015P	0.28
UCEC	chr3	122699754	Silent	novel	V400V	0.46
UCEC	chr3	122700945	Silent	novel	V797V	0.38
UCEC	chr3	122728584	Missense_Mutation	rs780103792	T1798M	0.34	PARP
UCEC	chr3	122701062	Silent	rs538044529	A836A	0.52
UCEC	chr3	122704641	Missense_Mutation	novel	A1145T	0.47
UCEC	chr3	122718461	Missense_Mutation	rs540312672	T1437M	0.42
UCEC	chr3	122718706	Nonsense_Mutation	rs776658320	R1519*	0.15
UCEC	chr3	122704682	Missense_Mutation	NA	K1158N	0.32
UCEC	chr3	122699847	Missense_Mutation	novel	E431D	0.26
UCEC	chr3	122701214	Missense_Mutation	novel	G887V	0.21
UCEC	chr3	122718091	Missense_Mutation	rs375767532	D1341N	0.1
UCEC	chr3	122727962	Missense_Mutation	NA	N1698D	0.19	PARP
UCEC	chr3	122687090	Missense_Mutation	novel	T111I	0.19
UCEC	chr3	122718547	Missense_Mutation	novel	D1466Y	0.13
UCEC	chr3	122720770	Intron	novel		0.09
UCEC	chr3	122714269	Missense_Mutation	novel	Q1280H	0.28
UCEC	chr3	122704640	Frame_Shift_Ins	novel	*A1145Tfs6**	0.07
UCEC	chr3	122701113	Frame_Shift_Ins	novel	*R855Efs35**	0.4
UCEC	chr3	122700419	Frame_Shift_Ins	novel	*K623Ffs11**	0.14
UCEC	chr3	122700530	Missense_Mutation	NA	K659T	0.43
UCEC	chr3	122718948	Silent	rs376801190	T1599T	0.39
UCEC	chr3	122727951	Missense_Mutation	rs748490431	R1694Q	0.08	PARP
UCEC	chr3	122700216	Missense_Mutation	NA	F554L	0.28
UCEC	chr3	122720496	Intron	novel		0.5
UCEC	chr3	122699659	Missense_Mutation	novel	A369T	0.46
UCEC	chr3	122700300	Silent	novel	S582S	0.35
UCEC	chr3	122713515	Silent	rs773729810	T1237T	0.34
UCEC	chr3	122685313	Missense_Mutation	novel	T106A	0.17
UCEC	chr3	122699846	Missense_Mutation	novel	E431V	0.19
UCEC	chr3	122718158	Missense_Mutation	novel	V1363A	0.2
UCEC	chr3	122718461	Missense_Mutation	rs540312672	T1437M	0.27
UCEC	chr3	122718706	Nonsense_Mutation	rs776658320	R1519*	0.42
UCEC	chr3	122728575	Missense_Mutation	novel	Y1795S	0.27	PARP
UCEC	chr3	122713425	Frame_Shift_Del	novel	*Y1209Mfs14**	0.26
UCEC	chr3	122728597	Silent	NA	*1802*	0.33
UCEC	chr3	122699688	Silent	rs770611577	P378P	0.27
UCEC	chr3	122720440	Intron	novel		0.42
UCEC	chr3	122728666	3'UTR	novel		0.92
UCEC	chr3	122700830	Missense_Mutation	rs754916464	R759Q	0.12
UCEC	chr3	122720340	Silent	rs371804973	T1631T	0.46
UCEC	chr3	122730735	3'UTR	novel		0.41
UCEC	chr3	122699565	Missense_Mutation	novel	K337N	0.43
UCEC	chr3	122699985	Silent	novel	R477R	0.3
UCEC	chr3	122703867	Silent	novel	V1069V	0.38
UCEC	chr3	122730677	3'UTR	novel		0.37
UCS	chr3	122701183	Missense_Mutation	rs752297915	V877M	0.18

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
GBM	DEL	0.0884	0.00094652
KIRC	DEL	0.1989	0.11092
LGG	DEL	0.0604	0.04374

Survival Analysis

Cancer	P-value	Q-value
SARC	0.0026	Kaplan-Meier Survival Analysis
MESO	0.04	Kaplan-Meier Survival Analysis
BRCA	0.041	Kaplan-Meier Survival Analysis
KIRP	0.0036	Kaplan-Meier Survival Analysis
PAAD	0.00089	Kaplan-Meier Survival Analysis
BLCA	0.0099	Kaplan-Meier Survival Analysis
CESC	0.012	Kaplan-Meier Survival Analysis
LAML	0.01	Kaplan-Meier Survival Analysis
UCEC	0.0049	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
THCA	0.0064	Kaplan-Meier Survival Analysis
UVM	0.046	Kaplan-Meier Survival Analysis