EuRBPDB

Description

RBDs

RBPome

PRI

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000173545 (Gene tree)
Gene ID: 90441
Gene Symbol: ZNF622
Alias: MGC2485|MGC17552|ZPR9
Full Name: zinc finger protein 622
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 18,809 bases
Position: chr5:16,451,519-16,470,327
Accession: 30958
RBP type: canonical RBP
Summary: (Zinc Finger Protein 622) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000310042	zf-met	PF12874.7	0.00023	1	1
ENSP00000310042	zf-C2H2_jaz	PF12171.8	7.7e-10	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000308683	ZNF622-201	1699	-	ENSP00000310042	477 (aa)	-	Q969S3

Gene Model

Click here to download ENSG00000173545's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000173545	Diabetic Nephropathies	3.6000000E-005	16775037
ENSG00000173545	Dextroamphetamine	6.1935000E-005	-
ENSG00000173545	Dextroamphetamine	4.8223000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000173545's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000173545	ZNF622	100	59.213	ENSAPOG00000018103	znf622	100	59.016	Acanthochromis_polyacanthus
ENSG00000173545	ZNF622	100	81.458	ENSAMEG00000015369	ZNF622	100	85.000	Ailuropoda_melanoleuca
ENSG00000173545	ZNF622	100	58.714	ENSACIG00000010939	znf622	100	58.714	Amphilophus_citrinellus
ENSG00000173545	ZNF622	100	59.544	ENSAOCG00000005659	znf622	100	58.144	Amphiprion_ocellaris
ENSG00000173545	ZNF622	100	59.544	ENSAPEG00000003157	znf622	100	58.144	Amphiprion_percula
ENSG00000173545	ZNF622	100	63.071	ENSATEG00000014287	znf622	100	62.241	Anabas_testudineus
ENSG00000173545	ZNF622	80	71.802	ENSAPLG00000006976	ZNF622	93	72.846	Anas_platyrhynchos
ENSG00000173545	ZNF622	100	68.763	ENSACAG00000000306	ZNF622	100	70.084	Anolis_carolinensis
ENSG00000173545	ZNF622	100	93.305	ENSANAG00000031551	-	100	94.770	Aotus_nancymaae
ENSG00000173545	ZNF622	100	59.671	ENSACLG00000024264	znf622	100	60.537	Astatotilapia_calliptera
ENSG00000173545	ZNF622	100	60.581	ENSAMXG00000019355	znf622	100	60.246	Astyanax_mexicanus
ENSG00000173545	ZNF622	100	84.067	ENSBTAG00000016441	ZNF622	93	82.390	Bos_taurus
ENSG00000173545	ZNF622	97	31.049	WBGene00015809	C16A3.4	82	40.000	Caenorhabditis_elegans
ENSG00000173545	ZNF622	100	93.711	ENSCJAG00000012047	ZNF622	100	93.291	Callithrix_jacchus
ENSG00000173545	ZNF622	99	78.481	ENSCAFG00000023607	ZNF622	100	78.270	Canis_familiaris
ENSG00000173545	ZNF622	100	78.261	ENSCAFG00020020158	ZNF622	100	77.593	Canis_lupus_dingo
ENSG00000173545	ZNF622	100	83.857	ENSCHIG00000007951	ZNF622	100	80.503	Capra_hircus
ENSG00000173545	ZNF622	100	88.565	ENSTSYG00000006612	ZNF622	100	86.279	Carlito_syrichta
ENSG00000173545	ZNF622	100	87.917	ENSCPOG00000002276	ZNF622	100	87.265	Cavia_porcellus
ENSG00000173545	ZNF622	100	94.969	ENSCCAG00000035492	ZNF622	100	94.969	Cebus_capucinus
ENSG00000173545	ZNF622	100	97.065	ENSCATG00000031254	ZNF622	100	97.065	Cercocebus_atys
ENSG00000173545	ZNF622	100	88.285	ENSCLAG00000011494	ZNF622	100	87.448	Chinchilla_lanigera
ENSG00000173545	ZNF622	100	96.855	ENSCSAG00000017262	ZNF622	100	96.855	Chlorocebus_sabaeus
ENSG00000173545	ZNF622	100	88.703	ENSCHOG00000010240	ZNF622	100	88.285	Choloepus_hoffmanni
ENSG00000173545	ZNF622	100	76.310	ENSCPBG00000021097	ZNF622	100	75.891	Chrysemys_picta_bellii
ENSG00000173545	ZNF622	62	57.843	ENSCING00000004045	-	74	56.410	Ciona_intestinalis
ENSG00000173545	ZNF622	99	44.513	ENSCSAVG00000005158	-	99	43.585	Ciona_savignyi
ENSG00000173545	ZNF622	100	97.904	ENSCANG00000034487	ZNF622	100	97.904	Colobus_angolensis_palliatus
ENSG00000173545	ZNF622	100	83.851	ENSCGRG00001024661	Zfp622	100	84.167	Cricetulus_griseus_chok1gshd
ENSG00000173545	ZNF622	100	83.851	ENSCGRG00000010522	Zfp622	100	84.167	Cricetulus_griseus_crigri
ENSG00000173545	ZNF622	100	60.334	ENSCSEG00000007253	znf622	97	59.834	Cynoglossus_semilaevis
ENSG00000173545	ZNF622	100	60.986	ENSCVAG00000010440	znf622	100	61.807	Cyprinodon_variegatus
ENSG00000173545	ZNF622	99	61.698	ENSDARG00000014692	znf622	99	61.698	Danio_rerio
ENSG00000173545	ZNF622	100	88.912	ENSDNOG00000035990	ZNF622	100	89.749	Dasypus_novemcinctus
ENSG00000173545	ZNF622	100	87.029	ENSDORG00000000939	Zfp622	100	86.192	Dipodomys_ordii
ENSG00000173545	ZNF622	75	52.083	FBgn0030878	CG6769	99	38.750	Drosophila_melanogaster
ENSG00000173545	ZNF622	100	82.744	ENSETEG00000005697	ZNF622	100	84.200	Echinops_telfairi
ENSG00000173545	ZNF622	100	48.133	ENSEBUG00000012613	znf622	100	47.737	Eptatretus_burgeri
ENSG00000173545	ZNF622	100	90.167	ENSEASG00005007253	ZNF622	100	88.494	Equus_asinus_asinus
ENSG00000173545	ZNF622	100	90.167	ENSECAG00000020350	ZNF622	100	88.494	Equus_caballus
ENSG00000173545	ZNF622	100	68.553	ENSEEUG00000003500	ZNF622	100	66.667	Erinaceus_europaeus
ENSG00000173545	ZNF622	100	59.714	ENSELUG00000017844	znf622	100	59.388	Esox_lucius
ENSG00000173545	ZNF622	99	87.866	ENSFCAG00000018947	ZNF622	97	87.866	Felis_catus
ENSG00000173545	ZNF622	100	72.803	ENSFALG00000007501	ZNF622	100	71.933	Ficedula_albicollis
ENSG00000173545	ZNF622	100	83.438	ENSFDAG00000011699	ZNF622	100	84.906	Fukomys_damarensis
ENSG00000173545	ZNF622	100	74.423	ENSGALG00000037171	ZNF622	100	74.843	Gallus_gallus
ENSG00000173545	ZNF622	100	60.000	ENSGAFG00000018571	znf622	100	59.167	Gambusia_affinis
ENSG00000173545	ZNF622	100	69.182	ENSGAGG00000004519	ZNF622	100	68.763	Gopherus_agassizii
ENSG00000173545	ZNF622	100	98.747	ENSGGOG00000009831	ZNF622	100	98.747	Gorilla_gorilla
ENSG00000173545	ZNF622	100	59.671	ENSHBUG00000011685	znf622	100	60.206	Haplochromis_burtoni
ENSG00000173545	ZNF622	100	88.100	ENSHGLG00000007811	ZNF622	100	88.100	Heterocephalus_glaber_female
ENSG00000173545	ZNF622	100	87.917	ENSHGLG00100014160	ZNF622	100	87.708	Heterocephalus_glaber_male
ENSG00000173545	ZNF622	100	59.298	ENSHCOG00000011311	znf622	100	58.932	Hippocampus_comes
ENSG00000173545	ZNF622	100	59.544	ENSIPUG00000008147	znf622	100	59.129	Ictalurus_punctatus
ENSG00000173545	ZNF622	100	90.417	ENSSTOG00000000623	ZNF622	100	90.417	Ictidomys_tridecemlineatus
ENSG00000173545	ZNF622	99	75.523	ENSJJAG00000000941	Zfp622	99	75.732	Jaculus_jaculus
ENSG00000173545	ZNF622	100	57.884	ENSKMAG00000000706	znf622	100	59.213	Kryptolebias_marmoratus
ENSG00000173545	ZNF622	100	60.124	ENSLBEG00000020022	znf622	98	60.206	Labrus_bergylta
ENSG00000173545	ZNF622	100	83.437	ENSLAFG00000031794	ZNF622	100	83.023	Loxodonta_africana
ENSG00000173545	ZNF622	100	97.275	ENSMFAG00000034147	ZNF622	100	97.275	Macaca_fascicularis
ENSG00000173545	ZNF622	100	97.484	ENSMNEG00000036952	ZNF622	100	97.484	Macaca_nemestrina
ENSG00000173545	ZNF622	100	96.226	ENSMLEG00000040466	ZNF622	100	96.226	Mandrillus_leucophaeus
ENSG00000173545	ZNF622	100	61.123	ENSMAMG00000015936	znf622	100	60.996	Mastacembelus_armatus
ENSG00000173545	ZNF622	100	59.671	ENSMZEG00005000470	znf622	100	60.537	Maylandia_zebra
ENSG00000173545	ZNF622	80	71.279	ENSMGAG00000005719	ZNF622	93	71.802	Meleagris_gallopavo
ENSG00000173545	ZNF622	100	83.264	ENSMAUG00000010395	Zfp622	100	83.264	Mesocricetus_auratus
ENSG00000173545	ZNF622	100	88.889	ENSMICG00000010544	ZNF622	100	89.727	Microcebus_murinus
ENSG00000173545	ZNF622	81	73.779	ENSMOCG00000001703	-	93	74.807	Microtus_ochrogaster
ENSG00000173545	ZNF622	100	82.845	ENSMOCG00000014111	-	100	83.195	Microtus_ochrogaster
ENSG00000173545	ZNF622	100	59.792	ENSMMOG00000011233	znf622	100	60.788	Mola_mola
ENSG00000173545	ZNF622	100	81.971	ENSMODG00000003459	ZNF622	100	81.551	Monodelphis_domestica
ENSG00000173545	ZNF622	100	83.473	ENSMPUG00000011110	ZNF622	100	82.845	Mustela_putorius_furo
ENSG00000173545	ZNF622	100	77.226	ENSMLUG00000007088	ZNF622	100	77.226	Myotis_lucifugus
ENSG00000173545	ZNF622	100	84.906	ENSNGAG00000012958	Zfp622	100	84.486	Nannospalax_galili
ENSG00000173545	ZNF622	100	54.658	ENSNBRG00000016286	znf622	100	54.865	Neolamprologus_brichardi
ENSG00000173545	ZNF622	100	97.484	ENSNLEG00000011876	ZNF622	100	97.484	Nomascus_leucogenys
ENSG00000173545	ZNF622	100	76.310	ENSMEUG00000004399	ZNF622	100	76.310	Notamacropus_eugenii
ENSG00000173545	ZNF622	100	77.778	ENSOPRG00000007806	ZNF622	100	76.778	Ochotona_princeps
ENSG00000173545	ZNF622	100	84.696	ENSODEG00000001594	-	100	85.115	Octodon_degus
ENSG00000173545	ZNF622	100	76.200	ENSODEG00000001750	-	100	76.827	Octodon_degus
ENSG00000173545	ZNF622	100	83.648	ENSODEG00000004409	-	100	84.167	Octodon_degus
ENSG00000173545	ZNF622	100	60.744	ENSONIG00000012409	znf622	100	61.284	Oreochromis_niloticus
ENSG00000173545	ZNF622	100	88.333	ENSOCUG00000017508	ZNF622	100	89.167	Oryctolagus_cuniculus
ENSG00000173545	ZNF622	100	59.167	ENSORLG00000006337	znf622	100	59.167	Oryzias_latipes
ENSG00000173545	ZNF622	100	59.459	ENSORLG00020020228	znf622	100	59.548	Oryzias_latipes_hni
ENSG00000173545	ZNF622	100	58.836	ENSORLG00015019466	znf622	100	58.664	Oryzias_latipes_hsok
ENSG00000173545	ZNF622	100	60.915	ENSOMEG00000020165	znf622	100	60.291	Oryzias_melastigma
ENSG00000173545	ZNF622	92	87.244	ENSOGAG00000014834	ZNF622	100	87.244	Otolemur_garnettii
ENSG00000173545	ZNF622	100	80.585	ENSOARG00000013083	ZNF622	100	78.706	Ovis_aries
ENSG00000173545	ZNF622	100	98.952	ENSPPAG00000028322	ZNF622	100	98.952	Pan_paniscus
ENSG00000173545	ZNF622	100	88.679	ENSPPRG00000008393	-	100	88.679	Panthera_pardus
ENSG00000173545	ZNF622	62	86.532	ENSPPRG00000008274	-	95	86.824	Panthera_pardus
ENSG00000173545	ZNF622	100	87.891	ENSPTIG00000009603	ZNF622	100	87.891	Panthera_tigris_altaica
ENSG00000173545	ZNF622	100	98.742	ENSPTRG00000016743	ZNF622	100	98.742	Pan_troglodytes
ENSG00000173545	ZNF622	99	96.421	ENSPANG00000009355	ZNF622	99	96.421	Papio_anubis
ENSG00000173545	ZNF622	100	61.111	ENSPKIG00000008000	znf622	100	62.162	Paramormyrops_kingsleyae
ENSG00000173545	ZNF622	100	75.105	ENSPSIG00000017092	ZNF622	100	74.686	Pelodiscus_sinensis
ENSG00000173545	ZNF622	100	57.884	ENSPMGG00000009276	znf622	100	57.292	Periophthalmus_magnuspinnatus
ENSG00000173545	ZNF622	100	84.067	ENSPEMG00000019901	-	100	83.648	Peromyscus_maniculatus_bairdii
ENSG00000173545	ZNF622	99	47.410	ENSPMAG00000000002	znf622	99	49.180	Petromyzon_marinus
ENSG00000173545	ZNF622	100	82.390	ENSPCIG00000025058	ZNF622	100	80.713	Phascolarctos_cinereus
ENSG00000173545	ZNF622	100	58.333	ENSPFOG00000001399	znf622	100	58.958	Poecilia_formosa
ENSG00000173545	ZNF622	100	58.958	ENSPLAG00000008990	znf622	95	58.750	Poecilia_latipinna
ENSG00000173545	ZNF622	100	58.958	ENSPMEG00000007146	znf622	100	59.583	Poecilia_mexicana
ENSG00000173545	ZNF622	100	59.583	ENSPREG00000020611	znf622	100	59.298	Poecilia_reticulata
ENSG00000173545	ZNF622	78	96.247	ENSPPYG00000029803	-	98	96.247	Pongo_abelii
ENSG00000173545	ZNF622	100	71.548	ENSPCAG00000002518	ZNF622	100	70.084	Procavia_capensis
ENSG00000173545	ZNF622	100	91.195	ENSPCOG00000020267	ZNF622	100	90.776	Propithecus_coquereli
ENSG00000173545	ZNF622	100	59.671	ENSPNYG00000016004	znf622	100	60.537	Pundamilia_nyererei
ENSG00000173545	ZNF622	100	87.002	ENSRNOG00000059443	LOC103690028	100	86.583	Rattus_norvegicus
ENSG00000173545	ZNF622	100	87.002	ENSRNOG00000010589	LOC103689968	100	86.583	Rattus_norvegicus
ENSG00000173545	ZNF622	100	97.694	ENSRBIG00000026260	ZNF622	100	97.694	Rhinopithecus_bieti
ENSG00000173545	ZNF622	100	97.694	ENSRROG00000033175	ZNF622	100	97.694	Rhinopithecus_roxellana
ENSG00000173545	ZNF622	100	92.872	ENSSBOG00000026590	ZNF622	100	92.872	Saimiri_boliviensis_boliviensis
ENSG00000173545	ZNF622	100	76.310	ENSSHAG00000004315	ZNF622	100	74.633	Sarcophilus_harrisii
ENSG00000173545	ZNF622	100	61.759	ENSSFOG00015020484	znf622	100	61.866	Scleropages_formosus
ENSG00000173545	ZNF622	100	59.465	ENSSMAG00000004950	znf622	100	59.298	Scophthalmus_maximus
ENSG00000173545	ZNF622	100	62.268	ENSSDUG00000005265	znf622	100	62.090	Seriola_dumerili
ENSG00000173545	ZNF622	100	61.237	ENSSLDG00000001508	znf622	100	61.554	Seriola_lalandi_dorsalis
ENSG00000173545	ZNF622	100	74.633	ENSSPUG00000013414	ZNF622	100	74.004	Sphenodon_punctatus
ENSG00000173545	ZNF622	100	61.042	ENSSPAG00000003954	znf622	100	61.042	Stegastes_partitus
ENSG00000173545	ZNF622	100	82.809	ENSSSCG00000016793	ZNF622	97	89.560	Sus_scrofa
ENSG00000173545	ZNF622	100	72.117	ENSTGUG00000007377	ZNF622	100	71.967	Taeniopygia_guttata
ENSG00000173545	ZNF622	99	59.748	ENSTNIG00000008000	znf622	99	58.750	Tetraodon_nigroviridis
ENSG00000173545	ZNF622	100	84.937	ENSUAMG00000024162	ZNF622	100	84.310	Ursus_americanus
ENSG00000173545	ZNF622	100	85.146	ENSUMAG00000021715	ZNF622	100	84.519	Ursus_maritimus
ENSG00000173545	ZNF622	51	79.808	ENSVPAG00000001286	-	60	80.412	Vicugna_pacos
ENSG00000173545	ZNF622	100	69.008	ENSXETG00000007539	znf622	100	68.041	Xenopus_tropicalis
ENSG00000173545	ZNF622	100	59.167	ENSXCOG00000019974	znf622	96	59.375	Xiphophorus_couchianus
ENSG00000173545	ZNF622	100	60.000	ENSXMAG00000006827	znf622	100	59.627	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	21771788.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	21771788.	IDA	Process
GO:0022625	cytosolic large ribosomal subunit	21873635.	IBA	Component
GO:0030687	preribosome, large subunit precursor	21873635.	IBA	Component
GO:0033674	positive regulation of kinase activity	21771788.	IDA	Process
GO:0042273	ribosomal large subunit biogenesis	21873635.	IBA	Process
GO:0043065	positive regulation of apoptotic process	21771788.	IDA	Process
GO:0043410	positive regulation of MAPK cascade	21771788.	IDA	Process
GO:0046330	positive regulation of JNK cascade	21771788.	IMP	Process