EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000173818 (Gene tree)
Gene ID: 284131
Gene Symbol: ENDOV
Alias: FLJ35220
Full Name: endonuclease V
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 22,970 bases
Position: chr17:80,415,117-80,438,086
Accession: 26640
RBP type: canonical RBP
Summary: (Endonuclease V) is a Protein Coding gene. Diseases associated with ENDOV include Uv-Sensitive Syndrome and Xeroderma Pigmentosum, Complementation Group A. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and single-stranded RNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000429190	Endonuclease_5	PF04493.14	9.5e-65	1	1
ENSP00000461563	Endonuclease_5	PF04493.14	2.2e-49	1	1
ENSP00000428283	Endonuclease_5	PF04493.14	1.5e-46	1	1
ENSP00000431036	Endonuclease_5	PF04493.14	4.9e-43	1	1
ENSP00000317810	Endonuclease_5	PF04493.14	7.5e-43	1	1
ENSP00000459127	Endonuclease_5	PF04493.14	3.5e-31	1	1
ENSP00000461060	Endonuclease_5	PF04493.14	3.7e-31	1	1
ENSP00000429603	Endonuclease_5	PF04493.14	1.1e-14	1	1
ENSP00000460685	Endonuclease_5	PF04493.14	9.4e-12	1	1
ENSP00000461577	Endonuclease_5	PF04493.14	9.4e-12	1	1
ENSP00000458185	Endonuclease_5	PF04493.14	1.7e-11	1	1
ENSP00000458361	Endonuclease_5	PF04493.14	2.5e-10	1	1
ENSP00000458391	Endonuclease_5	PF04493.14	2.5e-10	1	1
ENSP00000430509	Endonuclease_5	PF04493.14	4e-09	1	1
ENSP00000430639	Endonuclease_5	PF04493.14	5.3e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000523999	ENDOV-229	864	-	ENSP00000427921	105 (aa)	-	E5RFW0
ENST00000522751	ENDOV-225	1475	-	ENSP00000458185	115 (aa)	-	I3L0L4
ENST00000572886	ENDOV-230	334	-	ENSP00000461376	109 (aa)	-	I3L4M6
ENST00000523165	ENDOV-226	375	-	-	- (aa)	-	-
ENST00000520484	ENDOV-214	508	-	ENSP00000430046	123 (aa)	-	E5RGZ9
ENST00000519117	ENDOV-208	617	-	ENSP00000429183	97 (aa)	-	E5RJ92
ENST00000523228	ENDOV-227	545	-	ENSP00000429603	50 (aa)	-	E5RHX4
ENST00000520910	ENDOV-217	694	-	-	- (aa)	-	-
ENST00000519331	ENDOV-209	727	XM_011524672	ENSP00000430639	170 (aa)	XP_011522974	H0YBZ5
ENST00000520284	ENDOV-212	2500	XM_017024518	ENSP00000458391	65 (aa)	XP_016880007	Q8N8Q3
ENST00000518907	ENDOV-207	2418	-	ENSP00000458361	65 (aa)	-	Q8N8Q3
ENST00000521830	ENDOV-221	580	-	-	- (aa)	-	-
ENST00000518901	ENDOV-206	2549	-	ENSP00000460685	88 (aa)	-	Q8N8Q3
ENST00000520136	ENDOV-211	468	-	ENSP00000461194	3 (aa)	-	UPI000011D7C6
ENST00000523828	ENDOV-228	607	-	ENSP00000459831	8 (aa)	-	A0A0G2JLD4
ENST00000521330	ENDOV-218	556	-	-	- (aa)	-	-
ENST00000520118	ENDOV-210	533	-	-	- (aa)	-	-
ENST00000517295	ENDOV-202	908	XM_011524664	ENSP00000428283	236 (aa)	XP_011522966	H0YAY5
ENST00000522577	ENDOV-224	702	-	ENSP00000429442	138 (aa)	-	E5RII5
ENST00000521847	ENDOV-222	1847	-	-	- (aa)	-	-
ENST00000517795	ENDOV-203	2548	XM_017024515	ENSP00000461577	88 (aa)	XP_016880004	Q8N8Q3
ENST00000522200	ENDOV-223	855	-	ENSP00000461563	155 (aa)	-	I3L4V7
ENST00000521634	ENDOV-220	607	-	ENSP00000430509	131 (aa)	-	H0YBX8
ENST00000518137	ENDOV-204	2815	XM_006721837	ENSP00000429190	282 (aa)	XP_006721900	Q8N8Q3
ENST00000520565	ENDOV-216	433	-	-	- (aa)	-	-
ENST00000520537	ENDOV-215	690	-	-	- (aa)	-	-
ENST00000520367	ENDOV-213	2680	XM_017024511	ENSP00000431036	237 (aa)	XP_016880000	Q8N8Q3
ENST00000518644	ENDOV-205	625	-	ENSP00000461060	105 (aa)	-	I3L485
ENST00000521565	ENDOV-219	547	-	ENSP00000459127	97 (aa)	-	I3L1V3
ENST00000323854	ENDOV-201	1226	XM_005257246	ENSP00000317810	264 (aa)	XP_005257303	Q8N8Q3

Gene Model

Click here to download ENSG00000173818's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000173818's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000173818	ENDOV	100	64.000	ENSAPOG00000007037	ENDOV	98	60.163	Acanthochromis_polyacanthus
ENSG00000173818	ENDOV	100	86.598	ENSAMEG00000015304	ENDOV	98	80.714	Ailuropoda_melanoleuca
ENSG00000173818	ENDOV	100	64.000	ENSACIG00000020171	ENDOV	99	57.843	Amphilophus_citrinellus
ENSG00000173818	ENDOV	100	62.581	ENSAOCG00000018770	ENDOV	98	60.163	Amphiprion_ocellaris
ENSG00000173818	ENDOV	100	64.000	ENSATEG00000023498	ENDOV	96	61.304	Anabas_testudineus
ENSG00000173818	ENDOV	100	76.289	ENSAPLG00000003471	ENDOV	93	72.340	Anas_platyrhynchos
ENSG00000173818	ENDOV	100	73.196	ENSACAG00000015645	ENDOV	97	66.953	Anolis_carolinensis
ENSG00000173818	ENDOV	100	98.000	ENSANAG00000029466	ENDOV	100	91.844	Aotus_nancymaae
ENSG00000173818	ENDOV	100	64.000	ENSACLG00000010335	ENDOV	96	62.551	Astatotilapia_calliptera
ENSG00000173818	ENDOV	100	64.000	ENSAMXG00000015972	ENDOV	93	45.860	Astyanax_mexicanus
ENSG00000173818	ENDOV	100	85.567	ENSBTAG00000015339	ENDOV	98	78.929	Bos_taurus
ENSG00000173818	ENDOV	100	94.000	ENSCJAG00000003329	ENDOV	100	90.071	Callithrix_jacchus
ENSG00000173818	ENDOV	100	83.505	ENSCAFG00000005684	ENDOV	97	76.703	Canis_familiaris
ENSG00000173818	ENDOV	100	83.505	ENSCAFG00020008671	ENDOV	96	76.703	Canis_lupus_dingo
ENSG00000173818	ENDOV	100	85.567	ENSCHIG00000021238	ENDOV	93	76.000	Capra_hircus
ENSG00000173818	ENDOV	100	90.000	ENSTSYG00000005646	ENDOV	99	87.379	Carlito_syrichta
ENSG00000173818	ENDOV	100	80.000	ENSCAPG00000011313	-	86	70.256	Cavia_aperea
ENSG00000173818	ENDOV	100	73.718	ENSCPOG00000005529	ENDOV	98	75.769	Cavia_porcellus
ENSG00000173818	ENDOV	100	94.000	ENSCCAG00000035297	ENDOV	99	89.524	Cebus_capucinus
ENSG00000173818	ENDOV	100	100.000	ENSCATG00000042834	ENDOV	100	99.048	Cercocebus_atys
ENSG00000173818	ENDOV	100	83.226	ENSCLAG00000006305	ENDOV	98	81.143	Chinchilla_lanigera
ENSG00000173818	ENDOV	100	100.000	ENSCSAG00000002315	ENDOV	91	95.357	Chlorocebus_sabaeus
ENSG00000173818	ENDOV	100	74.000	ENSCPBG00000010525	ENDOV	90	71.345	Chrysemys_picta_bellii
ENSG00000173818	ENDOV	96	47.917	ENSCSAVG00000010293	-	95	40.556	Ciona_savignyi
ENSG00000173818	ENDOV	100	94.318	ENSCANG00000020058	ENDOV	99	94.915	Colobus_angolensis_palliatus
ENSG00000173818	ENDOV	100	89.691	ENSCGRG00001000788	Endov	97	76.344	Cricetulus_griseus_chok1gshd
ENSG00000173818	ENDOV	100	89.691	ENSCGRG00000016362	Endov	97	76.344	Cricetulus_griseus_crigri
ENSG00000173818	ENDOV	100	70.000	ENSCSEG00000015214	ENDOV	95	64.463	Cynoglossus_semilaevis
ENSG00000173818	ENDOV	100	70.000	ENSCVAG00000007166	ENDOV	95	63.333	Cyprinodon_variegatus
ENSG00000173818	ENDOV	100	80.769	ENSETEG00000014048	ENDOV	100	75.352	Echinops_telfairi
ENSG00000173818	ENDOV	100	61.856	ENSEBUG00000011943	ENDOV	79	58.291	Eptatretus_burgeri
ENSG00000173818	ENDOV	100	90.722	ENSEASG00005005482	ENDOV	76	83.929	Equus_asinus_asinus
ENSG00000173818	ENDOV	100	90.722	ENSECAG00000012208	ENDOV	76	83.571	Equus_caballus
ENSG00000173818	ENDOV	74	78.462	ENSEEUG00000007625	-	72	73.626	Erinaceus_europaeus
ENSG00000173818	ENDOV	100	64.000	ENSELUG00000008464	ENDOV	94	63.025	Esox_lucius
ENSG00000173818	ENDOV	100	84.536	ENSFCAG00000031769	ENDOV	100	81.000	Felis_catus
ENSG00000173818	ENDOV	98	73.469	ENSFALG00000012475	ENDOV	93	66.279	Ficedula_albicollis
ENSG00000173818	ENDOV	100	78.344	ENSFDAG00000013275	ENDOV	82	80.889	Fukomys_damarensis
ENSG00000173818	ENDOV	66	65.116	ENSFHEG00000003086	ENDOV	70	50.847	Fundulus_heteroclitus
ENSG00000173818	ENDOV	100	58.333	ENSGMOG00000017580	ENDOV	98	61.304	Gadus_morhua
ENSG00000173818	ENDOV	100	73.196	ENSGALG00000006963	ENDOV	89	66.667	Gallus_gallus
ENSG00000173818	ENDOV	100	70.000	ENSGAFG00000007756	ENDOV	99	61.885	Gambusia_affinis
ENSG00000173818	ENDOV	100	66.000	ENSGACG00000018198	ENDOV	99	63.180	Gasterosteus_aculeatus
ENSG00000173818	ENDOV	100	74.000	ENSGAGG00000022130	ENDOV	89	67.364	Gopherus_agassizii
ENSG00000173818	ENDOV	100	100.000	ENSGGOG00000010209	ENDOV	100	99.153	Gorilla_gorilla
ENSG00000173818	ENDOV	100	64.000	ENSHBUG00000001543	ENDOV	96	62.551	Haplochromis_burtoni
ENSG00000173818	ENDOV	100	84.000	ENSHGLG00000004976	ENDOV	98	80.682	Heterocephalus_glaber_female
ENSG00000173818	ENDOV	100	60.759	ENSHCOG00000013813	ENDOV	88	58.750	Hippocampus_comes
ENSG00000173818	ENDOV	100	65.806	ENSIPUG00000022104	endov	99	60.484	Ictalurus_punctatus
ENSG00000173818	ENDOV	100	90.722	ENSSTOG00000027436	ENDOV	97	80.402	Ictidomys_tridecemlineatus
ENSG00000173818	ENDOV	100	92.000	ENSJJAG00000014912	-	97	83.333	Jaculus_jaculus
ENSG00000173818	ENDOV	100	66.000	ENSKMAG00000011618	ENDOV	80	62.555	Kryptolebias_marmoratus
ENSG00000173818	ENDOV	100	64.000	ENSLBEG00000013183	ENDOV	96	61.826	Labrus_bergylta
ENSG00000173818	ENDOV	100	78.000	ENSLACG00000016911	ENDOV	96	65.289	Latimeria_chalumnae
ENSG00000173818	ENDOV	100	61.290	ENSLOCG00000013414	ENDOV	84	60.504	Lepisosteus_oculatus
ENSG00000173818	ENDOV	100	82.474	ENSLAFG00000026661	ENDOV	100	67.391	Loxodonta_africana
ENSG00000173818	ENDOV	100	100.000	ENSMFAG00000044601	ENDOV	100	99.048	Macaca_fascicularis
ENSG00000173818	ENDOV	100	100.000	ENSMMUG00000001285	ENDOV	100	99.048	Macaca_mulatta
ENSG00000173818	ENDOV	100	100.000	ENSMNEG00000020009	ENDOV	100	99.048	Macaca_nemestrina
ENSG00000173818	ENDOV	100	87.826	ENSMLEG00000032858	ENDOV	100	93.913	Mandrillus_leucophaeus
ENSG00000173818	ENDOV	100	64.000	ENSMAMG00000005788	ENDOV	98	60.400	Mastacembelus_armatus
ENSG00000173818	ENDOV	100	64.000	ENSMZEG00005011897	ENDOV	82	60.714	Maylandia_zebra
ENSG00000173818	ENDOV	100	88.660	ENSMAUG00000021480	Endov	83	78.369	Mesocricetus_auratus
ENSG00000173818	ENDOV	100	85.806	ENSMICG00000037907	ENDOV	100	82.857	Microcebus_murinus
ENSG00000173818	ENDOV	100	86.598	ENSMOCG00000019008	Endov	97	72.376	Microtus_ochrogaster
ENSG00000173818	ENDOV	100	60.000	ENSMMOG00000006981	ENDOV	68	56.395	Mola_mola
ENSG00000173818	ENDOV	100	78.351	ENSMODG00000002372	ENDOV	96	72.951	Monodelphis_domestica
ENSG00000173818	ENDOV	100	68.000	ENSMALG00000006274	ENDOV	81	63.889	Monopterus_albus
ENSG00000173818	ENDOV	100	86.598	MGP_CAROLIEiJ_G0017500	Endov	97	75.000	Mus_caroli
ENSG00000173818	ENDOV	100	86.598	ENSMUSG00000039850	Endov	100	73.500	Mus_musculus
ENSG00000173818	ENDOV	100	87.629	MGP_PahariEiJ_G0018627	Endov	97	75.758	Mus_pahari
ENSG00000173818	ENDOV	100	86.598	MGP_SPRETEiJ_G0018344	Endov	93	83.922	Mus_spretus
ENSG00000173818	ENDOV	100	88.660	ENSMPUG00000012082	ENDOV	93	81.679	Mustela_putorius_furo
ENSG00000173818	ENDOV	100	90.722	ENSNGAG00000021532	-	98	84.000	Nannospalax_galili
ENSG00000173818	ENDOV	100	100.000	ENSNLEG00000015754	ENDOV	100	99.048	Nomascus_leucogenys
ENSG00000173818	ENDOV	100	80.412	ENSMEUG00000010606	ENDOV	100	78.082	Notamacropus_eugenii
ENSG00000173818	ENDOV	100	82.000	ENSOPRG00000013691	ENDOV	99	80.085	Ochotona_princeps
ENSG00000173818	ENDOV	100	81.290	ENSODEG00000009857	-	98	80.114	Octodon_degus
ENSG00000173818	ENDOV	100	64.000	ENSONIG00000003328	ENDOV	99	60.816	Oreochromis_niloticus
ENSG00000173818	ENDOV	100	84.000	ENSOCUG00000024779	ENDOV	100	76.538	Oryctolagus_cuniculus
ENSG00000173818	ENDOV	100	62.581	ENSORLG00015014346	ENDOV	97	61.905	Oryzias_latipes_hsok
ENSG00000173818	ENDOV	100	66.000	ENSOMEG00000006436	ENDOV	96	60.744	Oryzias_melastigma
ENSG00000173818	ENDOV	100	82.474	ENSOGAG00000027594	ENDOV	98	76.173	Otolemur_garnettii
ENSG00000173818	ENDOV	100	85.567	ENSOARG00000000766	ENDOV	94	77.385	Ovis_aries
ENSG00000173818	ENDOV	100	100.000	ENSPPAG00000034689	ENDOV	100	98.729	Pan_paniscus
ENSG00000173818	ENDOV	100	86.000	ENSPPRG00000011602	ENDOV	96	82.397	Panthera_pardus
ENSG00000173818	ENDOV	100	100.000	ENSPTRG00000009745	ENDOV	100	98.582	Pan_troglodytes
ENSG00000173818	ENDOV	100	100.000	ENSPANG00000019621	ENDOV	100	99.048	Papio_anubis
ENSG00000173818	ENDOV	100	61.290	ENSPKIG00000006685	ENDOV	95	60.417	Paramormyrops_kingsleyae
ENSG00000173818	ENDOV	100	74.227	ENSPSIG00000007239	ENDOV	89	67.063	Pelodiscus_sinensis
ENSG00000173818	ENDOV	100	64.000	ENSPMGG00000010309	ENDOV	96	59.804	Periophthalmus_magnuspinnatus
ENSG00000173818	ENDOV	100	88.660	ENSPEMG00000009075	Endov	98	78.804	Peromyscus_maniculatus_bairdii
ENSG00000173818	ENDOV	100	80.412	ENSPCIG00000029110	ENDOV	84	72.727	Phascolarctos_cinereus
ENSG00000173818	ENDOV	100	68.000	ENSPFOG00000016616	ENDOV	94	65.417	Poecilia_formosa
ENSG00000173818	ENDOV	100	68.000	ENSPMEG00000002323	ENDOV	97	63.600	Poecilia_mexicana
ENSG00000173818	ENDOV	100	66.000	ENSPREG00000002988	ENDOV	87	63.441	Poecilia_reticulata
ENSG00000173818	ENDOV	100	100.000	ENSPPYG00000008721	ENDOV	91	96.429	Pongo_abelii
ENSG00000173818	ENDOV	100	80.000	ENSPCAG00000011432	ENDOV	96	76.015	Procavia_capensis
ENSG00000173818	ENDOV	100	82.581	ENSPCOG00000027446	ENDOV	100	80.496	Propithecus_coquereli
ENSG00000173818	ENDOV	100	83.505	ENSPVAG00000014077	ENDOV	99	60.714	Pteropus_vampyrus
ENSG00000173818	ENDOV	100	64.000	ENSPNAG00000028276	ENDOV	98	59.921	Pygocentrus_nattereri
ENSG00000173818	ENDOV	100	86.598	ENSRNOG00000003699	Endov	98	82.500	Rattus_norvegicus
ENSG00000173818	ENDOV	100	100.000	ENSRBIG00000042566	ENDOV	100	99.048	Rhinopithecus_bieti
ENSG00000173818	ENDOV	100	100.000	ENSRROG00000037314	ENDOV	100	99.048	Rhinopithecus_roxellana
ENSG00000173818	ENDOV	100	98.000	ENSSBOG00000020840	ENDOV	99	91.429	Saimiri_boliviensis_boliviensis
ENSG00000173818	ENDOV	100	76.000	ENSSHAG00000008416	ENDOV	100	72.269	Sarcophilus_harrisii
ENSG00000173818	ENDOV	100	66.000	ENSSFOG00015004419	endov	95	61.826	Scleropages_formosus
ENSG00000173818	ENDOV	100	64.516	ENSSMAG00000011539	ENDOV	91	55.932	Scophthalmus_maximus
ENSG00000173818	ENDOV	100	64.000	ENSSDUG00000003581	ENDOV	94	62.917	Seriola_dumerili
ENSG00000173818	ENDOV	100	63.226	ENSSLDG00000001821	ENDOV	95	60.417	Seriola_lalandi_dorsalis
ENSG00000173818	ENDOV	98	71.429	ENSSPAG00000014755	ENDOV	98	62.195	Stegastes_partitus
ENSG00000173818	ENDOV	100	82.474	ENSSSCG00000030277	ENDOV	94	77.157	Sus_scrofa
ENSG00000173818	ENDOV	98	73.469	ENSTGUG00000003057	ENDOV	100	67.811	Taeniopygia_guttata
ENSG00000173818	ENDOV	100	60.000	ENSTRUG00000004474	ENDOV	96	48.361	Takifugu_rubripes
ENSG00000173818	ENDOV	100	64.000	ENSTNIG00000006743	-	88	63.636	Tetraodon_nigroviridis
ENSG00000173818	ENDOV	100	64.000	ENSTNIG00000006611	-	99	60.338	Tetraodon_nigroviridis
ENSG00000173818	ENDOV	100	64.000	ENSTNIG00000006755	ENDOV	98	59.649	Tetraodon_nigroviridis
ENSG00000173818	ENDOV	100	90.000	ENSTTRG00000000545	ENDOV	100	74.035	Tursiops_truncatus
ENSG00000173818	ENDOV	100	87.629	ENSUAMG00000027555	ENDOV	94	79.188	Ursus_americanus
ENSG00000173818	ENDOV	100	87.629	ENSUMAG00000015201	ENDOV	92	83.817	Ursus_maritimus
ENSG00000173818	ENDOV	100	85.567	ENSVVUG00000018497	-	98	79.545	Vulpes_vulpes
ENSG00000173818	ENDOV	100	66.000	ENSXETG00000019623	endov	94	63.529	Xenopus_tropicalis
ENSG00000173818	ENDOV	100	70.000	ENSXCOG00000011592	ENDOV	77	64.516	Xiphophorus_couchianus
ENSG00000173818	ENDOV	100	70.000	ENSXMAG00000017948	ENDOV	99	65.263	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000287	magnesium ion binding	-	ISS	Function
GO:0000287	magnesium ion binding	23912683.	TAS	Function
GO:0003677	DNA binding	23139746.	IDA	Function
GO:0003727	single-stranded RNA binding	21873635.	IBA	Function
GO:0003727	single-stranded RNA binding	23912683.23912718.	IDA	Function
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	23139746.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	23139746.23912718.	IDA	Component
GO:0006281	DNA repair	-	ISS	Process
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	23139746.23912683.	IDA	Function
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	-	ISS	Function
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	21873635.	IBA	Function
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	23912683.23912718.	IDA	Function
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process