EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000174173 (Gene tree)
Gene ID: 54931
Gene Symbol: TRMT10C
Alias: FLJ20432|MRPP1|RG9MTD1
Full Name: tRNA methyltransferase 10C, mitochondrial RNase P subunit
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 4,611 bases
Position: chr3:101,561,836-101,566,446
Accession: 26022
RBP type: canonical RBP
Summary: This gene encodes the precursor of a subunit of the mitochondrial ribonuclease P, which is involved in 5' processing of mitochondrial tRNAs. The encoded protein may confer RNA-binding capacity to mitochondrial ribonuclease P and may be essential for transcript processing, RNA modification, translation and mitochondrial respiration. [provided by RefSeq, Nov 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000312356	tRNA_m1G_MT	PF01746.21	2.9e-40	1	1
ENSP00000419389	tRNA_m1G_MT	PF01746.21	2.2e-23	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000309922	TRMT10C-201	1819	-	ENSP00000312356	403 (aa)	-	Q7L0Y3
ENST00000495642	TRMT10C-202	1017	-	ENSP00000419389	312 (aa)	-	C9JVB6

Gene Model

Click here to download ENSG00000174173's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000174173's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000174173	TRMT10C	59	31.984	ENSAPOG00000007362	trmt10b	72	31.984	Acanthochromis_polyacanthus
ENSG00000174173	TRMT10C	62	57.480	ENSAPOG00000003883	trmt10c	72	57.480	Acanthochromis_polyacanthus
ENSG00000174173	TRMT10C	99	77.444	ENSAMEG00000019657	TRMT10C	96	77.444	Ailuropoda_melanoleuca
ENSG00000174173	TRMT10C	59	32.927	ENSAOCG00000001205	trmt10b	80	32.927	Amphiprion_ocellaris
ENSG00000174173	TRMT10C	56	61.504	ENSAOCG00000005855	trmt10c	66	61.304	Amphiprion_ocellaris
ENSG00000174173	TRMT10C	56	61.947	ENSAPEG00000021992	trmt10c	66	61.739	Amphiprion_percula
ENSG00000174173	TRMT10C	59	32.389	ENSAPEG00000003675	trmt10b	78	32.389	Amphiprion_percula
ENSG00000174173	TRMT10C	73	56.667	ENSATEG00000012576	trmt10c	79	56.667	Anabas_testudineus
ENSG00000174173	TRMT10C	96	49.873	ENSAPLG00000011561	TRMT10C	97	49.873	Anas_platyrhynchos
ENSG00000174173	TRMT10C	87	55.337	ENSACAG00000011903	TRMT10C	81	56.742	Anolis_carolinensis
ENSG00000174173	TRMT10C	95	47.739	ENSACLG00000024269	trmt10c	94	48.241	Astatotilapia_calliptera
ENSG00000174173	TRMT10C	87	49.718	ENSAMXG00000014749	trmt10c	84	49.718	Astyanax_mexicanus
ENSG00000174173	TRMT10C	99	80.952	ENSBTAG00000024027	TRMT10C	95	80.952	Bos_taurus
ENSG00000174173	TRMT10C	100	74.631	ENSCAFG00000031607	TRMT10C	95	74.631	Canis_familiaris
ENSG00000174173	TRMT10C	100	74.877	ENSCAFG00020008862	TRMT10C	95	74.877	Canis_lupus_dingo
ENSG00000174173	TRMT10C	100	79.012	ENSCHIG00000021446	TRMT10C	95	79.012	Capra_hircus
ENSG00000174173	TRMT10C	100	74.752	ENSCLAG00000017738	TRMT10C	95	74.752	Chinchilla_lanigera
ENSG00000174173	TRMT10C	100	90.446	ENSCSAG00000018722	TRMT10C	100	90.123	Chlorocebus_sabaeus
ENSG00000174173	TRMT10C	100	77.460	ENSCHOG00000010108	TRMT10C	100	77.892	Choloepus_hoffmanni
ENSG00000174173	TRMT10C	98	71.429	ENSCGRG00001006603	Trmt10c	96	71.392	Cricetulus_griseus_chok1gshd
ENSG00000174173	TRMT10C	98	71.429	ENSCGRG00000019728	Trmt10c	96	71.392	Cricetulus_griseus_crigri
ENSG00000174173	TRMT10C	89	44.730	ENSCSEG00000006163	trmt10c	78	45.128	Cynoglossus_semilaevis
ENSG00000174173	TRMT10C	86	50.000	ENSCVAG00000013751	trmt10c	73	50.000	Cyprinodon_variegatus
ENSG00000174173	TRMT10C	82	49.702	ENSDARG00000041575	trmt10c	85	53.629	Danio_rerio
ENSG00000174173	TRMT10C	99	72.932	ENSDNOG00000012650	TRMT10C	95	72.932	Dasypus_novemcinctus
ENSG00000174173	TRMT10C	99	77.945	ENSDORG00000027529	Trmt10c	96	77.945	Dipodomys_ordii
ENSG00000174173	TRMT10C	68	34.146	FBgn0034351	rswl	64	34.146	Drosophila_melanogaster
ENSG00000174173	TRMT10C	84	35.777	ENSEBUG00000015332	trmt10c	81	35.777	Eptatretus_burgeri
ENSG00000174173	TRMT10C	100	83.121	ENSEASG00005011186	TRMT10C	96	82.469	Equus_asinus_asinus
ENSG00000174173	TRMT10C	100	83.121	ENSECAG00000001533	TRMT10C	96	82.222	Equus_caballus
ENSG00000174173	TRMT10C	99	71.216	ENSEEUG00000004696	TRMT10C	99	71.216	Erinaceus_europaeus
ENSG00000174173	TRMT10C	86	53.977	ENSELUG00000002553	trmt10c	83	53.977	Esox_lucius
ENSG00000174173	TRMT10C	100	78.025	ENSFCAG00000003430	TRMT10C	95	78.465	Felis_catus
ENSG00000174173	TRMT10C	83	55.224	ENSFALG00000014236	TRMT10C	86	52.459	Ficedula_albicollis
ENSG00000174173	TRMT10C	100	74.321	ENSFDAG00000001576	TRMT10C	94	74.321	Fukomys_damarensis
ENSG00000174173	TRMT10C	81	52.137	ENSFHEG00000015379	trmt10c	69	52.137	Fundulus_heteroclitus
ENSG00000174173	TRMT10C	81	51.057	ENSGMOG00000008573	trmt10c	95	51.057	Gadus_morhua
ENSG00000174173	TRMT10C	87	52.676	ENSGALG00000015328	TRMT10C	85	52.676	Gallus_gallus
ENSG00000174173	TRMT10C	53	63.256	ENSGAFG00000012256	trmt10c	69	63.256	Gambusia_affinis
ENSG00000174173	TRMT10C	94	49.482	ENSGACG00000015281	trmt10c	95	49.482	Gasterosteus_aculeatus
ENSG00000174173	TRMT10C	85	59.357	ENSGAGG00000022825	TRMT10C	79	60.704	Gopherus_agassizii
ENSG00000174173	TRMT10C	100	98.511	ENSGGOG00000006484	TRMT10C	100	98.511	Gorilla_gorilla
ENSG00000174173	TRMT10C	52	61.611	ENSHBUG00000000010	trmt10c	64	61.611	Haplochromis_burtoni
ENSG00000174173	TRMT10C	100	73.086	ENSHGLG00000019767	TRMT10C	98	74.074	Heterocephalus_glaber_female
ENSG00000174173	TRMT10C	100	73.086	ENSHGLG00100020191	TRMT10C	98	74.074	Heterocephalus_glaber_male
ENSG00000174173	TRMT10C	54	60.181	ENSHCOG00000003493	trmt10c	81	60.181	Hippocampus_comes
ENSG00000174173	TRMT10C	94	48.371	ENSIPUG00000010010	trmt10c	82	48.371	Ictalurus_punctatus
ENSG00000174173	TRMT10C	100	79.455	ENSSTOG00000012199	TRMT10C	96	79.455	Ictidomys_tridecemlineatus
ENSG00000174173	TRMT10C	86	50.141	ENSKMAG00000022027	trmt10c	82	50.141	Kryptolebias_marmoratus
ENSG00000174173	TRMT10C	95	46.717	ENSLBEG00000013143	trmt10c	79	46.717	Labrus_bergylta
ENSG00000174173	TRMT10C	84	56.534	ENSLACG00000002036	TRMT10C	92	56.250	Latimeria_chalumnae
ENSG00000174173	TRMT10C	85	51.282	ENSLOCG00000017802	trmt10c	79	51.282	Lepisosteus_oculatus
ENSG00000174173	TRMT10C	99	78.697	ENSLAFG00000009677	TRMT10C	96	78.697	Loxodonta_africana
ENSG00000174173	TRMT10C	100	90.446	ENSMMUG00000017780	TRMT10C	96	90.370	Macaca_mulatta
ENSG00000174173	TRMT10C	55	56.696	ENSMAMG00000003124	trmt10c	66	56.696	Mastacembelus_armatus
ENSG00000174173	TRMT10C	52	61.611	ENSMZEG00005000671	trmt10c	64	61.611	Maylandia_zebra
ENSG00000174173	TRMT10C	65	52.672	ENSMGAG00000014375	TRMT10C	98	52.672	Meleagris_gallopavo
ENSG00000174173	TRMT10C	99	73.935	ENSMAUG00000009904	Trmt10c	96	73.935	Mesocricetus_auratus
ENSG00000174173	TRMT10C	98	74.436	ENSMOCG00000020572	Trmt10c	96	74.436	Microtus_ochrogaster
ENSG00000174173	TRMT10C	63	51.779	ENSMMOG00000018106	trmt10c	73	51.779	Mola_mola
ENSG00000174173	TRMT10C	98	57.051	ENSMODG00000025175	TRMT10C	92	59.231	Monodelphis_domestica
ENSG00000174173	TRMT10C	91	47.826	ENSMALG00000016236	trmt10c	79	47.570	Monopterus_albus
ENSG00000174173	TRMT10C	99	76.942	MGP_CAROLIEiJ_G0020812	Trmt10c	96	76.942	Mus_caroli
ENSG00000174173	TRMT10C	99	76.942	ENSMUSG00000044763	Trmt10c	96	76.942	Mus_musculus
ENSG00000174173	TRMT10C	99	76.692	MGP_PahariEiJ_G0016512	Trmt10c	96	76.692	Mus_pahari
ENSG00000174173	TRMT10C	99	77.444	MGP_SPRETEiJ_G0021712	Trmt10c	96	77.444	Mus_spretus
ENSG00000174173	TRMT10C	100	78.662	ENSMPUG00000019979	TRMT10C	95	78.272	Mustela_putorius_furo
ENSG00000174173	TRMT10C	100	77.707	ENSMLUG00000030097	-	97	77.916	Myotis_lucifugus
ENSG00000174173	TRMT10C	98	77.922	ENSMLUG00000028638	-	96	77.834	Myotis_lucifugus
ENSG00000174173	TRMT10C	98	75.188	ENSNGAG00000022215	Trmt10c	96	75.188	Nannospalax_galili
ENSG00000174173	TRMT10C	55	59.375	ENSNBRG00000017903	trmt10c	90	57.083	Neolamprologus_brichardi
ENSG00000174173	TRMT10C	100	78.571	ENSOPRG00000007388	TRMT10C	100	78.571	Ochotona_princeps
ENSG00000174173	TRMT10C	81	50.893	ENSONIG00000003128	trmt10c	89	51.488	Oreochromis_niloticus
ENSG00000174173	TRMT10C	91	56.369	ENSOANG00000007508	TRMT10C	99	57.995	Ornithorhynchus_anatinus
ENSG00000174173	TRMT10C	100	79.618	ENSOCUG00000011103	TRMT10C	95	78.025	Oryctolagus_cuniculus
ENSG00000174173	TRMT10C	99	42.771	ENSORLG00000004992	trmt10c	79	46.914	Oryzias_latipes
ENSG00000174173	TRMT10C	84	50.696	ENSORLG00020016083	trmt10c	71	50.696	Oryzias_latipes_hni
ENSG00000174173	TRMT10C	99	42.598	ENSORLG00015014590	trmt10c	79	47.395	Oryzias_latipes_hsok
ENSG00000174173	TRMT10C	58	57.692	ENSOMEG00000016820	trmt10c	85	57.692	Oryzias_melastigma
ENSG00000174173	TRMT10C	99	78.000	ENSOGAG00000001819	TRMT10C	96	78.000	Otolemur_garnettii
ENSG00000174173	TRMT10C	99	80.299	ENSOARG00000001677	TRMT10C	95	80.299	Ovis_aries
ENSG00000174173	TRMT10C	100	78.344	ENSPTIG00000002271	TRMT10C	95	78.960	Panthera_tigris_altaica
ENSG00000174173	TRMT10C	100	98.759	ENSPTRG00000051763	-	100	98.759	Pan_troglodytes
ENSG00000174173	TRMT10C	100	98.759	ENSPTRG00000015171	TRMT10C	100	98.759	Pan_troglodytes
ENSG00000174173	TRMT10C	82	51.020	ENSPKIG00000010307	trmt10c	74	51.895	Paramormyrops_kingsleyae
ENSG00000174173	TRMT10C	99	54.950	ENSPSIG00000004052	TRMT10C	99	54.950	Pelodiscus_sinensis
ENSG00000174173	TRMT10C	53	57.870	ENSPMGG00000001599	trmt10c	75	57.870	Periophthalmus_magnuspinnatus
ENSG00000174173	TRMT10C	99	75.439	ENSPEMG00000006986	Trmt10c	96	75.439	Peromyscus_maniculatus_bairdii
ENSG00000174173	TRMT10C	98	59.204	ENSPCIG00000016080	TRMT10C	94	59.204	Phascolarctos_cinereus
ENSG00000174173	TRMT10C	81	54.277	ENSPFOG00000009282	trmt10c	83	54.277	Poecilia_formosa
ENSG00000174173	TRMT10C	56	58.442	ENSPLAG00000010774	trmt10c	83	58.442	Poecilia_latipinna
ENSG00000174173	TRMT10C	54	60.092	ENSPMEG00000023060	trmt10c	76	60.092	Poecilia_mexicana
ENSG00000174173	TRMT10C	83	51.247	ENSPREG00000021808	trmt10c	71	51.247	Poecilia_reticulata
ENSG00000174173	TRMT10C	100	95.062	ENSPPYG00000013592	TRMT10C	95	95.062	Pongo_abelii
ENSG00000174173	TRMT10C	100	76.543	ENSPCAG00000001290	TRMT10C	100	76.543	Procavia_capensis
ENSG00000174173	TRMT10C	100	80.247	ENSPVAG00000009885	TRMT10C	100	80.247	Pteropus_vampyrus
ENSG00000174173	TRMT10C	99	46.778	ENSPNYG00000003607	trmt10c	96	47.255	Pundamilia_nyererei
ENSG00000174173	TRMT10C	51	33.333	ENSPNYG00000021439	trmt10b	70	33.333	Pundamilia_nyererei
ENSG00000174173	TRMT10C	53	63.256	ENSPNAG00000010519	trmt10c	69	63.256	Pygocentrus_nattereri
ENSG00000174173	TRMT10C	99	75.439	ENSRNOG00000039567	Trmt10c	96	75.439	Rattus_norvegicus
ENSG00000174173	TRMT10C	95	85.492	ENSSBOG00000023326	TRMT10C	100	85.492	Saimiri_boliviensis_boliviensis
ENSG00000174173	TRMT10C	99	57.494	ENSSHAG00000008854	TRMT10C	94	57.494	Sarcophilus_harrisii
ENSG00000174173	TRMT10C	82	52.616	ENSSFOG00015008704	trmt10c	78	52.616	Scleropages_formosus
ENSG00000174173	TRMT10C	94	45.939	ENSSMAG00000021322	trmt10c	77	45.939	Scophthalmus_maximus
ENSG00000174173	TRMT10C	99	44.755	ENSSDUG00000006430	trmt10c	89	44.988	Seriola_dumerili
ENSG00000174173	TRMT10C	63	56.202	ENSSLDG00000001023	trmt10c	81	56.202	Seriola_lalandi_dorsalis
ENSG00000174173	TRMT10C	99	76.675	ENSSARG00000014342	TRMT10C	100	76.675	Sorex_araneus
ENSG00000174173	TRMT10C	93	50.171	ENSSPUG00000018495	TRMT10C	95	49.105	Sphenodon_punctatus
ENSG00000174173	TRMT10C	78	53.292	ENSSPAG00000016082	trmt10c	81	53.292	Stegastes_partitus
ENSG00000174173	TRMT10C	59	32.794	ENSSPAG00000004689	trmt10b	78	32.794	Stegastes_partitus
ENSG00000174173	TRMT10C	99	81.454	ENSSSCG00000011956	TRMT10C	96	81.454	Sus_scrofa
ENSG00000174173	TRMT10C	82	56.627	ENSTGUG00000013621	TRMT10C	99	56.627	Taeniopygia_guttata
ENSG00000174173	TRMT10C	71	51.007	ENSTRUG00000024252	trmt10c	89	51.007	Takifugu_rubripes
ENSG00000174173	TRMT10C	86	50.000	ENSTNIG00000009440	trmt10c	94	50.000	Tetraodon_nigroviridis
ENSG00000174173	TRMT10C	99	78.554	ENSTBEG00000013894	TRMT10C	99	78.554	Tupaia_belangeri
ENSG00000174173	TRMT10C	99	80.952	ENSTTRG00000015004	TRMT10C	99	80.952	Tursiops_truncatus
ENSG00000174173	TRMT10C	99	78.697	ENSUAMG00000017378	TRMT10C	96	78.697	Ursus_americanus
ENSG00000174173	TRMT10C	99	78.947	ENSUMAG00000003252	TRMT10C	96	78.947	Ursus_maritimus
ENSG00000174173	TRMT10C	100	74.568	ENSVVUG00000021735	TRMT10C	92	74.568	Vulpes_vulpes
ENSG00000174173	TRMT10C	93	50.260	ENSXETG00000029921	trmt10c	96	57.028	Xenopus_tropicalis
ENSG00000174173	TRMT10C	68	55.986	ENSXCOG00000002876	trmt10c	92	56.690	Xiphophorus_couchianus
ENSG00000174173	TRMT10C	81	51.977	ENSXMAG00000019205	trmt10c	70	52.542	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	21873635.	IBA	Function
GO:0000049	tRNA binding	29040705.	IDA	Function
GO:0000964	mitochondrial RNA 5'-end processing	21593607.	IMP	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	21873635.	IBA	Function
GO:0005515	protein binding	18984158.23042678.29040705.	IPI	Function
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	23042678.	IDA	Component
GO:0005739	mitochondrion	27132592.	IMP	Component
GO:0005759	mitochondrial matrix	-	TAS	Component
GO:0009019	tRNA (guanine-N1-)-methyltransferase activity	21873635.	IBA	Function
GO:0009019	tRNA (guanine-N1-)-methyltransferase activity	23042678.	IDA	Function
GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	21873635.	IBA	Function
GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	23042678.	IDA	Function
GO:0030678	mitochondrial ribonuclease P complex	21873635.	IBA	Component
GO:0030678	mitochondrial ribonuclease P complex	23042678.	TAS	Component
GO:0042645	mitochondrial nucleoid	-	IEA	Component
GO:0052905	tRNA (guanine(9)-N(1))-methyltransferase activity	-	IEA	Function
GO:0061953	mRNA (adenine-N1-)-methyltransferase activity	21873635.	IBA	Function
GO:0061953	mRNA (adenine-N1-)-methyltransferase activity	29072297.	IDA	Function
GO:0070131	positive regulation of mitochondrial translation	21873635.	IBA	Process
GO:0070131	positive regulation of mitochondrial translation	27132592.	IMP	Process
GO:0070901	mitochondrial tRNA methylation	-	TAS	Process
GO:0080009	mRNA methylation	29072297.	IDA	Process
GO:0090646	mitochondrial tRNA processing	21873635.	IBA	Process
GO:0090646	mitochondrial tRNA processing	27132592.	IMP	Process
GO:0090646	mitochondrial tRNA processing	-	TAS	Process
GO:0097745	mitochondrial tRNA 5'-end processing	29040705.	IDA	Process
GO:1990180	mitochondrial tRNA 3'-end processing	21873635.	IBA	Process
GO:1990180	mitochondrial tRNA 3'-end processing	29040705.	IDA	Process