EuRBPDB

  • Home
  • Cancer
  • Family
  • Species
  • RBPredictor
  • Search
  • Download
  • Submit
  • Help
  • Contact

  • Description
  • RBDs
  • RBPome
  • PRI
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000174231 (Gene tree)
Gene ID
10594
Gene Symbol
PRPF8
Alias
PRPC8|Prp8|hPrp8|SNRNP220|RP13
Full Name
pre-mRNA processing factor 8
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
34,254 bases
Position
chr17:1,650,629-1,684,882
Accession
17340
RBP type
canonical RBP
Summary
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000304350RRM_4PF10598.91.2e-4711
ENSP00000460348RRM_4PF10598.91.2e-4711
ENSP00000458151RRM_4PF10598.94.4e-4311
ENSP00000304350U5_2-snRNA_bdgPF10597.92.4e-7311
ENSP00000460348U5_2-snRNA_bdgPF10597.92.4e-7311
ENSP00000460849U5_2-snRNA_bdgPF10597.93e-2311
ENSP00000304350PRO8NTPF08082.114.9e-8611
ENSP00000460348PRO8NTPF08082.114.9e-8611
ENSP00000458151PRO8NTPF08082.115.7e-4312
ENSP00000458151PRO8NTPF08082.115.7e-4322
ENSP00000460849U6-snRNA_bdgPF10596.92e-9011
ENSP00000304350U6-snRNA_bdgPF10596.95.9e-8911
ENSP00000460348U6-snRNA_bdgPF10596.95.9e-8911
ENSP00000458151PROCNPF08083.111e-23511
ENSP00000304350PROCNPF08083.116.4e-23511
ENSP00000460348PROCNPF08083.116.4e-23511
ENSP00000304350PRP8_domainIVPF12134.81.3e-12911
ENSP00000460348PRP8_domainIVPF12134.81.3e-12911
ENSP00000304350PROCTPF08084.115e-5311
ENSP00000460348PROCTPF08084.115e-5311
ENSP00000459095PROCTPF08084.114e-2211
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
Protein-RNA interaction(RNA-Binding Site)
Click here to download all RNA binding sites
Click here to download all RNA binding sites

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
23704370Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.Science2013 Jul 5Mozaffari-Jovin Sdoi: 10.1126/science.1237515
23393194Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.Nucleic Acids Res2013 Apr 1Li Xdoi: 10.1093/nar/gkt062
27072132Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase Activity.J Biol Chem2016 Jun 3Ledoux Sdoi: 10.1074/jbc.M115.710848
26968627Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.RNA2016 MayMayerle Mdoi: 10.1261/rna.055459.115
29377672Molecular Mechanism and Evolution of Nuclear Pre-mRNA and Group II Intron Splicing: Insights from Cryo-Electron Microscopy Structures.Chem Rev2018 Apr 25Galej WPdoi: 10.1021/acs.chemrev.7b00499
21441348Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase.RNA2011 MayDlakic Mdoi: 10.1261/rna.2396011
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000571346PRPF8-202865--- (aa)--
ENST00000573716PRPF8-208542--- (aa)--
ENST00000573681PRPF8-2071044--- (aa)--
ENST00000574728PRPF8-211466--- (aa)--
ENST00000576958PRPF8-215416--- (aa)--
ENST00000572621PRPF8-2057445-ENSP000004603482335 (aa)-Q6P2Q9
ENST00000573725PRPF8-209749-ENSP00000460849250 (aa)-I3L3Z8
ENST00000572445PRPF8-204648--- (aa)--
ENST00000576585PRPF8-2142157--- (aa)--
ENST00000576407PRPF8-213566--- (aa)--
ENST00000572723PRPF8-206959--- (aa)--
ENST00000575116PRPF8-212460--- (aa)--
ENST00000574217PRPF8-210310--- (aa)--
ENST00000577001PRPF8-2163274-ENSP000004581511012 (aa)-I3L0J9
ENST00000571958PRPF8-203380-ENSP00000459095116 (aa)-I3L1T8
ENST00000304992PRPF8-2017295XM_024450537ENSP000003043502335 (aa)XP_024306305Q6P2Q9
Gene Model
Click here to download ENSG00000174231's gene model file
Pathways
Pathway IDPathway NameSource
hsa03040SpliceosomeKEGG
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000174231rs8071756171671048GBlood protein levels28240269[0.49-0.69] unit increase0.5897EFO_0008276
ENSG00000174231rs11867415171668524?Stroke29531354EFO_0000712
ENSG00000174231rs11867415171668524?Ischemic stroke29531354HP_0002140
ENSG00000174231rs62089970171672578CBlood protein levels30072576[1.13-1.43] unit decrease1.276EFO_0007937
ENSG00000174231rs11867415171668524?Ischemic stroke29531354HP_0002140
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000174231's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000174231PRPF810097.820ENSAPOG00000010079prpf810097.820Acanthochromis_polyacanthus
ENSG00000174231PRPF8100100.000ENSAMEG00000007940PRPF8100100.000Ailuropoda_melanoleuca
ENSG00000174231PRPF810095.549ENSACIG00000018280prpf810095.925Amphilophus_citrinellus
ENSG00000174231PRPF810097.820ENSAOCG00000010725prpf810097.820Amphiprion_ocellaris
ENSG00000174231PRPF810097.820ENSAPEG00000014397prpf810097.820Amphiprion_percula
ENSG00000174231PRPF810097.263ENSATEG00000010062prpf810097.263Anabas_testudineus
ENSG00000174231PRPF89699.555ENSAPLG00000010357PRPF810099.555Anas_platyrhynchos
ENSG00000174231PRPF89993.358ENSACAG00000014784PRPF89997.477Anolis_carolinensis
ENSG00000174231PRPF8100100.000ENSANAG00000032629PRPF8100100.000Aotus_nancymaae
ENSG00000174231PRPF810097.447ENSACLG00000020858prpf810097.447Astatotilapia_calliptera
ENSG00000174231PRPF810097.731ENSAMXG00000020291prpf810097.731Astyanax_mexicanus
ENSG00000174231PRPF8100100.000ENSBTAG00000011488PRPF8100100.000Bos_taurus
ENSG00000174231PRPF89986.444WBGene00004187prp-89986.529Caenorhabditis_elegans
ENSG00000174231PRPF8100100.000ENSCJAG00000001911PRPF8100100.000Callithrix_jacchus
ENSG00000174231PRPF8100100.000ENSCAFG00000019221PRPF8100100.000Canis_familiaris
ENSG00000174231PRPF896100.000ENSCAFG00020009943PRPF8100100.000Canis_lupus_dingo
ENSG00000174231PRPF8100100.000ENSCHIG00000017499PRPF8100100.000Capra_hircus
ENSG00000174231PRPF8100100.000ENSTSYG00000014120PRPF8100100.000Carlito_syrichta
ENSG00000174231PRPF89697.773ENSCAPG00000009459PRPF89997.773Cavia_aperea
ENSG00000174231PRPF8100100.000ENSCPOG00000010379PRPF8100100.000Cavia_porcellus
ENSG00000174231PRPF8100100.000ENSCCAG00000031983-100100.000Cebus_capucinus
ENSG00000174231PRPF8100100.000ENSCATG00000038595PRPF8100100.000Cercocebus_atys
ENSG00000174231PRPF8100100.000ENSCLAG00000004388PRPF8100100.000Chinchilla_lanigera
ENSG00000174231PRPF8100100.000ENSCSAG00000013929PRPF8100100.000Chlorocebus_sabaeus
ENSG00000174231PRPF882100.000ENSCHOG00000008590PRPF88899.738Choloepus_hoffmanni
ENSG00000174231PRPF810099.529ENSCPBG00000020409PRPF810099.529Chrysemys_picta_bellii
ENSG00000174231PRPF899100.000ENSCSAVG00000007825-10091.280Ciona_savignyi
ENSG00000174231PRPF8100100.000ENSCANG00000043088PRPF8100100.000Colobus_angolensis_palliatus
ENSG00000174231PRPF89594.510ENSCGRG00001017673-98100.000Cricetulus_griseus_chok1gshd
ENSG00000174231PRPF882100.000ENSCGRG00000005129Prpf810099.409Cricetulus_griseus_crigri
ENSG00000174231PRPF810097.649ENSCSEG00000007905prpf810097.649Cynoglossus_semilaevis
ENSG00000174231PRPF810097.609ENSDARG00000026180prpf810097.609Danio_rerio
ENSG00000174231PRPF810094.752ENSDNOG00000018471PRPF89999.954Dasypus_novemcinctus
ENSG00000174231PRPF810094.047ENSDORG00000006185Prpf89699.432Dipodomys_ordii
ENSG00000174231PRPF89991.549FBgn0033688Prp89891.122Drosophila_melanogaster
ENSG00000174231PRPF810094.518ENSETEG00000017592PRPF810094.518Echinops_telfairi
ENSG00000174231PRPF89993.729ENSEBUG00000006548prpf89993.729Eptatretus_burgeri
ENSG00000174231PRPF8100100.000ENSEASG00005009514PRPF8100100.000Equus_asinus_asinus
ENSG00000174231PRPF897100.000ENSECAG00000021318PRPF8100100.000Equus_caballus
ENSG00000174231PRPF88291.748ENSEEUG00000012120-67100.000Erinaceus_europaeus
ENSG00000174231PRPF89896.547ENSELUG00000007120prpf89996.547Esox_lucius
ENSG00000174231PRPF8100100.000ENSFCAG00000006297PRPF8100100.000Felis_catus
ENSG00000174231PRPF810099.486ENSFALG00000006628PRPF810099.486Ficedula_albicollis
ENSG00000174231PRPF8100100.000ENSFDAG00000004711PRPF8100100.000Fukomys_damarensis
ENSG00000174231PRPF810097.438ENSFHEG00000021084prpf810097.438Fundulus_heteroclitus
ENSG00000174231PRPF810095.389ENSGMOG00000002028prpf89995.389Gadus_morhua
ENSG00000174231PRPF810099.443ENSGALG00000002943PRPF810099.443Gallus_gallus
ENSG00000174231PRPF89997.520ENSGAFG00000010337prpf89997.520Gambusia_affinis
ENSG00000174231PRPF810097.516ENSGACG00000008504prpf810097.516Gasterosteus_aculeatus
ENSG00000174231PRPF810099.529ENSGAGG00000008350PRPF810099.529Gopherus_agassizii
ENSG00000174231PRPF8100100.000ENSGGOG00000005516PRPF8100100.000Gorilla_gorilla
ENSG00000174231PRPF810097.604ENSHBUG00000016192prpf810097.604Haplochromis_burtoni
ENSG00000174231PRPF8100100.000ENSHGLG00000012029PRPF8100100.000Heterocephalus_glaber_female
ENSG00000174231PRPF8100100.000ENSHGLG00100016494PRPF8100100.000Heterocephalus_glaber_male
ENSG00000174231PRPF810097.563ENSHCOG00000016414prpf810097.563Hippocampus_comes
ENSG00000174231PRPF810097.605ENSIPUG00000023230prpf810097.605Ictalurus_punctatus
ENSG00000174231PRPF8100100.000ENSSTOG00000005128PRPF8100100.000Ictidomys_tridecemlineatus
ENSG00000174231PRPF810097.816ENSJJAG00000021159Prpf810097.816Jaculus_jaculus
ENSG00000174231PRPF89997.977ENSKMAG00000016118prpf89997.977Kryptolebias_marmoratus
ENSG00000174231PRPF810097.478ENSLBEG00000026903prpf810097.478Labrus_bergylta
ENSG00000174231PRPF810091.839ENSLACG00000010479PRPF89998.551Latimeria_chalumnae
ENSG00000174231PRPF89997.731ENSLOCG00000005409prpf89997.731Lepisosteus_oculatus
ENSG00000174231PRPF8100100.000ENSLAFG00000015445PRPF8100100.000Loxodonta_africana
ENSG00000174231PRPF8100100.000ENSMFAG00000039995PRPF8100100.000Macaca_fascicularis
ENSG00000174231PRPF8100100.000ENSMMUG00000004820PRPF8100100.000Macaca_mulatta
ENSG00000174231PRPF8100100.000ENSMNEG00000035713PRPF8100100.000Macaca_nemestrina
ENSG00000174231PRPF8100100.000ENSMLEG00000037937PRPF8100100.000Mandrillus_leucophaeus
ENSG00000174231PRPF810097.776ENSMAMG00000008919prpf810097.776Mastacembelus_armatus
ENSG00000174231PRPF810097.447ENSMZEG00005015073prpf810097.447Maylandia_zebra
ENSG00000174231PRPF810099.443ENSMGAG00000004769PRPF810099.443Meleagris_gallopavo
ENSG00000174231PRPF810099.957ENSMICG00000010320PRPF810099.957Microcebus_murinus
ENSG00000174231PRPF810099.957ENSMOCG00000016838Prpf810099.957Microtus_ochrogaster
ENSG00000174231PRPF810097.305ENSMMOG00000011887prpf810097.305Mola_mola
ENSG00000174231PRPF810099.829ENSMODG00000010480PRPF810099.829Monodelphis_domestica
ENSG00000174231PRPF89797.713ENSMALG00000003558prpf810097.713Monopterus_albus
ENSG00000174231PRPF8100100.000MGP_CAROLIEiJ_G0016740Prpf810099.914Mus_caroli
ENSG00000174231PRPF8100100.000ENSMUSG00000020850Prpf810099.914Mus_musculus
ENSG00000174231PRPF810099.901MGP_PahariEiJ_G0017877Prpf810099.829Mus_pahari
ENSG00000174231PRPF8100100.000MGP_SPRETEiJ_G0017583Prpf810099.914Mus_spretus
ENSG00000174231PRPF8100100.000ENSMPUG00000013227PRPF8100100.000Mustela_putorius_furo
ENSG00000174231PRPF810099.786ENSMLUG00000002666PRPF810099.786Myotis_lucifugus
ENSG00000174231PRPF810098.201ENSNGAG00000005305Prpf810098.201Nannospalax_galili
ENSG00000174231PRPF810097.489ENSNBRG00000013127prpf810097.489Neolamprologus_brichardi
ENSG00000174231PRPF89797.695ENSNLEG00000000897PRPF89897.695Nomascus_leucogenys
ENSG00000174231PRPF89998.044ENSMEUG00000015999PRPF810098.044Notamacropus_eugenii
ENSG00000174231PRPF810098.458ENSOPRG00000003102PRPF810098.458Ochotona_princeps
ENSG00000174231PRPF8100100.000ENSODEG00000008468PRPF8100100.000Octodon_degus
ENSG00000174231PRPF810097.490ENSONIG00000008153prpf810097.490Oreochromis_niloticus
ENSG00000174231PRPF88399.645ENSOANG00000004250PRPF89799.720Ornithorhynchus_anatinus
ENSG00000174231PRPF8100100.000ENSOCUG00000000081PRPF8100100.000Oryctolagus_cuniculus
ENSG00000174231PRPF89997.687ENSORLG00000008036prpf89997.687Oryzias_latipes
ENSG00000174231PRPF89997.646ENSORLG00020021070prpf89997.646Oryzias_latipes_hni
ENSG00000174231PRPF89997.687ENSORLG00015002340prpf89997.687Oryzias_latipes_hsok
ENSG00000174231PRPF89996.187ENSOMEG00000016866prpf89996.187Oryzias_melastigma
ENSG00000174231PRPF810099.872ENSOARG00000013312PRPF810099.872Ovis_aries
ENSG00000174231PRPF8100100.000ENSPPAG00000042753PRPF8100100.000Pan_paniscus
ENSG00000174231PRPF8100100.000ENSPPRG00000008746PRPF8100100.000Panthera_pardus
ENSG00000174231PRPF810099.914ENSPTIG00000019200PRPF810099.914Panthera_tigris_altaica
ENSG00000174231PRPF8100100.000ENSPTRG00000039576PRPF8100100.000Pan_troglodytes
ENSG00000174231PRPF89999.057ENSPANG00000024607PRPF89999.057Papio_anubis
ENSG00000174231PRPF810097.319ENSPKIG00000011201prpf810097.319Paramormyrops_kingsleyae
ENSG00000174231PRPF810099.486ENSPSIG00000013393PRPF810099.486Pelodiscus_sinensis
ENSG00000174231PRPF810099.957ENSPEMG00000021699Prpf810099.957Peromyscus_maniculatus_bairdii
ENSG00000174231PRPF89693.853ENSPMAG00000005438prpf810093.898Petromyzon_marinus
ENSG00000174231PRPF810099.829ENSPCIG00000022603PRPF810099.866Phascolarctos_cinereus
ENSG00000174231PRPF810096.990ENSPFOG00000007005prpf810096.990Poecilia_formosa
ENSG00000174231PRPF810096.403ENSPLAG00000020777prpf810096.403Poecilia_latipinna
ENSG00000174231PRPF810096.990ENSPMEG00000004051prpf810096.990Poecilia_mexicana
ENSG00000174231PRPF810097.645ENSPREG00000021902prpf810097.645Poecilia_reticulata
ENSG00000174231PRPF8100100.000ENSPPYG00000007777PRPF8100100.000Pongo_abelii
ENSG00000174231PRPF89099.647ENSPCAG00000008938PRPF89099.647Procavia_capensis
ENSG00000174231PRPF810099.957ENSPCOG00000015182PRPF810099.957Propithecus_coquereli
ENSG00000174231PRPF893100.000ENSPVAG00000002134PRPF893100.000Pteropus_vampyrus
ENSG00000174231PRPF810097.604ENSPNYG00000016356prpf810097.604Pundamilia_nyererei
ENSG00000174231PRPF810097.648ENSPNAG00000009247prpf810097.648Pygocentrus_nattereri
ENSG00000174231PRPF810099.914ENSRNOG00000003495Prpf810099.914Rattus_norvegicus
ENSG00000174231PRPF8100100.000ENSRBIG00000031219PRPF8100100.000Rhinopithecus_bieti
ENSG00000174231PRPF8100100.000ENSRROG00000038014PRPF8100100.000Rhinopithecus_roxellana
ENSG00000174231PRPF89979.612YHR165CPRP89562.516Saccharomyces_cerevisiae
ENSG00000174231PRPF8100100.000ENSSBOG00000029717PRPF8100100.000Saimiri_boliviensis_boliviensis
ENSG00000174231PRPF810099.786ENSSHAG00000006167PRPF810099.786Sarcophilus_harrisii
ENSG00000174231PRPF810097.523ENSSFOG00015013905prpf810097.523Scleropages_formosus
ENSG00000174231PRPF810097.394ENSSMAG00000017736prpf810097.394Scophthalmus_maximus
ENSG00000174231PRPF810097.776ENSSDUG00000003029prpf810097.776Seriola_dumerili
ENSG00000174231PRPF882100.000ENSSLDG00000017096prpf810098.936Seriola_lalandi_dorsalis
ENSG00000174231PRPF88799.395ENSSARG00000002892PRPF88799.395Sorex_araneus
ENSG00000174231PRPF810099.315ENSSPUG00000007463PRPF810099.315Sphenodon_punctatus
ENSG00000174231PRPF810097.221ENSSPAG00000015639prpf810097.221Stegastes_partitus
ENSG00000174231PRPF8100100.000ENSSSCG00000017817PRPF8100100.000Sus_scrofa
ENSG00000174231PRPF87499.099ENSTGUG00000015597-9599.651Taeniopygia_guttata
ENSG00000174231PRPF810099.486ENSTGUG00000005648-10099.486Taeniopygia_guttata
ENSG00000174231PRPF810097.563ENSTRUG00000015906prpf810097.563Takifugu_rubripes
ENSG00000174231PRPF89598.746ENSTNIG00000003460prpf89998.746Tetraodon_nigroviridis
ENSG00000174231PRPF89399.932ENSTBEG00000006431PRPF89399.932Tupaia_belangeri
ENSG00000174231PRPF810099.400ENSTTRG00000006869PRPF810099.400Tursiops_truncatus
ENSG00000174231PRPF810094.752ENSUAMG00000015644-9699.921Ursus_americanus
ENSG00000174231PRPF882100.000ENSUAMG00000028213-100100.000Ursus_americanus
ENSG00000174231PRPF810099.743ENSUMAG00000009385PRPF810099.743Ursus_maritimus
ENSG00000174231PRPF87199.505ENSVPAG00000006063-7199.505Vicugna_pacos
ENSG00000174231PRPF8100100.000ENSVVUG00000021695PRPF899100.000Vulpes_vulpes
ENSG00000174231PRPF810098.716ENSXETG00000022259prpf810098.716Xenopus_tropicalis
ENSG00000174231PRPF810097.566ENSXCOG00000012775prpf810097.566Xiphophorus_couchianus
ENSG00000174231PRPF810097.523ENSXMAG00000008505prpf810097.523Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000244spliceosomal tri-snRNP complex assembly21873635.IBAProcess
GO:0000244spliceosomal tri-snRNP complex assembly20595234.IDAProcess
GO:0000375RNA splicing, via transesterification reactions9774689.TASProcess
GO:0000386second spliceosomal transesterification activity21873635.IBAFunction
GO:0000398mRNA splicing, via spliceosome11991638.ICProcess
GO:0000398mRNA splicing, via spliceosome28781166.IDAProcess
GO:0000398mRNA splicing, via spliceosome-TASProcess
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding9774689.18951082.20696395.22365833.22720776.23704370.23793891.26711270.IPIFunction
GO:0005634nucleus22720776.28781166.IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005682U5 snRNP21873635.IBAComponent
GO:0006397mRNA processing9774689.TASProcess
GO:0008380RNA splicing9774689.TASProcess
GO:0016020membrane19946888.HDAComponent
GO:0016607nuclear speck-IEAComponent
GO:0017070U6 snRNA binding21873635.IBAFunction
GO:0030619U1 snRNA binding21873635.IBAFunction
GO:0030620U2 snRNA binding21873635.IBAFunction
GO:0030623U5 snRNA binding21873635.IBAFunction
GO:0046540U4/U6 x U5 tri-snRNP complex23793891.IDAComponent
GO:0070530K63-linked polyubiquitin modification-dependent protein binding20595234.IDAFunction
GO:0071005U2-type precatalytic spliceosome28781166.IDAComponent
GO:0071007U2-type catalytic step 2 spliceosome28076346.IDAComponent
GO:0071013catalytic step 2 spliceosome21873635.IBAComponent
GO:0071013catalytic step 2 spliceosome11991638.IDAComponent
GO:0071222cellular response to lipopolysaccharide-IEAProcess
GO:0071356cellular response to tumor necrosis factor-IEAProcess
GO:0097157pre-mRNA intronic binding21873635.IBAFunction

Copyright © , Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.

Any comment and suggestion, please contact us