23240926 | Evidence of a low prevalence of RAS mutations in a large medullary thyroid cancer series. | Thyroid | 2013 Jan | Ciampi R | doi: 10.1089/thy.2012.0207 |
26522772 | H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases. | J Pediatr Urol | 2016 Apr | Castillo-Martin M | doi: 10.1016/j.jpurol.2015.08.020 |
21330833 | Genetic alterations in the K-Ras gene influence the prognosis in patients with cervical cancer treated by radiotherapy. | Int J Gynecol Cancer | 2011 Jan | Wegman P | doi: 10.1097/IGC.0b013e3182049924. |
27074591 | Impact of SNPs on CpG Islands in the MYC and HRAS oncogenes and in a wide variety of tumor suppressor genes: A multi-cancer approach. | Cell Cycle | 2016 Jun 17 | Samy MD | doi: 10.1080/15384101.2016.1164360. |
28371260 | Phenotypic spectrum of Costello syndrome individuals harboring the rare HRAS mutation p.Gly13Asp. | Am J Med Genet A | 2017 May | Bertola D | doi: 10.1002/ajmg.a.38178 |
22427690 | Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature. | J Cell Sci | 2012 Jul 1 | Solomon H | doi: 10.1242/jcs.099663 |
22982396 | Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. | J Biol Chem | 2012 Nov 30 | Liu Y | doi: 10.1074/jbc.M112.367847 |
19254697 | Comparison of ras-responsive gene enhancers in pancreatic tumor cells that express either wild-type or mutant K-ras. | Biochem Biophys Res Commun | 2009 Apr 17 | Wilder PJ | doi: 10.1016/j.bbrc.2009.02.126 |
17374253 | [K-ras mutation analysis in ovarian serous borderline and malignant tumors]. | Zhonghua Bing Li Xue Za Zhi | 2006 Dec | Ma L | - |
23028055 | Ras oncoproteins transfer from melanoma cells to T cells and modulate their effector functions. | J Immunol | 2012 Nov 1 | Vernitsky H | doi: 10.4049/jimmunol.1200019 |
22573884 | Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V. | Mol Biol Cell | 2012 Jul | Schmees C | doi: 10.1091/mbc.E11-04-0317 |
16286246 | Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. | Cancer Cell | 2005 Nov | Lim KH | - |
19101897 | Mutations of RAS gene family in specimens of bladder cancer. | Urol J | 2008 Fall | Karimianpour N | - |
17096025 | The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. | Cell Death Differ | 2007 May | Shapira S | - |
21665306 | In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status. | Radiother Oncol | 2011 Oct | Myllynen L | doi: 10.1016/j.radonc.2011.05.046 |
15816642 | Persistence of K-ras mutations in plasma after colorectal tumor resection. | Anticancer Res | 2005 Jan-Feb | Lindforss U | - |
19140325 | [Molecular-genetic analysis of clonal intratumoral heterogeneity on colorectal adenocarcinomas]. | Mol Biol (Mosk) | 2008 Nov-Dec | Nemtsova MN | - |
22589270 | A comprehensive survey of Ras mutations in cancer. | Cancer Res | 2012 May 15 | Prior IA | doi: 10.1158/0008-5472.CAN-11-2612. |
16738062 | p19ras brings a new twist to the regulation of p73 by Mdm2. | Sci STKE | 2006 May 30 | Harms KL | - |
23583409 | p53 Attenuates the oncogenic Ras-induced epithelial-mesenchymal transition in human mammary epithelial cells. | Biochem Biophys Res Commun | 2013 May 10 | Zhang J | doi: 10.1016/j.bbrc.2013.03.124 |
21473856 | RASSF1A suppresses the activated K-Ras-induced oxidative DNA damage. | Biochem Biophys Res Commun | 2011 Apr 29 | Park SH | doi: 10.1016/j.bbrc.2011.03.139 |
18465119 | Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane. | Arch Toxicol | 2008 Oct | Jin M | doi: 10.1007/s00204-008-0293-y |
19855428 | Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation. | Oncogene | 2009 Dec 17 | Aylon Y | doi: 10.1038/onc.2009.270 |
26620726 | MicroRNAs: Modulators of the Ras Oncogenes in Oral Cancer. | J Cell Physiol | 2016 Jul | Murugan AK | doi: 10.1002/jcp.25269 |
26560143 | Absolute Quantification of Endogenous Ras Isoform Abundance. | PLoS One | 2015 Nov 11 | Mageean CJ | doi: 10.1371/journal.pone.0142674 |
24908601 | Combined mutational analysis of RAS, BRAF, PIK3CA, and TP53 genes in Taiwanese patients with oral squamous cell carcinoma. | Oral Surg Oral Med Oral Pathol Oral Radiol | 2014 Jul | Chang YS | doi: 10.1016/j.oooo.2014.03.016 |
26568031 | Phenotypic Screening Identifies Protein Synthesis Inhibitors as H-Ras-Nanocluster-Increasing Tumor Growth Inducers. | Biochemistry | 2015 Dec 15 | Najumudeen AK | doi: 10.1021/acs.biochem.5b00724 |
27913610 | Whole exome sequencing of thymic neuroendocrine tumor with ectopic ACTH syndrome. | Eur J Endocrinol | 2017 Feb | Li Y | - |
30655611 | WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. | Nat Commun | 2019 Jan 17 | Jeong WJ | doi: 10.1038/s41467-018-08230-6. |
22490849 | [Association between H-ras and L-myc gene polymorphisms and susceptibility to colorectal cancer]. | Zhonghua Zhong Liu Za Zhi | 2012 Jan | Ni Q | - |
28259994 | Overexpression of wild-type p21Ras plays a prominent role in colorectal cancer. | Int J Mol Med | 2017 Apr | Bai S | doi: 10.3892/ijmm.2017.2903 |
16857742 | Ras-dependent recruitment of c-Myc for transcriptional activation of nucleophosmin/B23 in highly malignant U1 bladder cancer cells. | Mol Pharmacol | 2006 Oct | Yeh CW | - |
22707223 | Methylation pattern of oncogene HRAS gene promoter region and its clinical relevance to urocystic tumorigenesis. | Mol Biol Rep | 2012 Aug | Sun XF | doi: 10.1007/s11033-012-1696-7 |
18783589 | Association between H-RAS T81C genetic polymorphism and gastrointestinal cancer risk: a population based case-control study in China. | BMC Cancer | 2008 Sep 10 | Zhang Y | doi: 10.1186/1471-2407-8-256. |
23264394 | Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS. | J Clin Endocrinol Metab | 2013 Feb | Agrawal N | doi: 10.1210/jc.2012-2703 |
21080251 | Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China. | Tumour Biol | 2011 Apr | Chen HC | doi: 10.1007/s13277-010-0129-2 |
21514184 | HRAS T81C polymorphism modulates risk of urinary bladder cancer and predicts advanced tumors in ethnic Kashmiri population. | Urol Oncol | 2013 May | Pandith AA | doi: 10.1016/j.urolonc.2011.03.004 |
24648519 | Ras-induced epigenetic inactivation of the RRAD (Ras-related associated with diabetes) gene promotes glucose uptake in a human ovarian cancer model. | J Biol Chem | 2014 May 16 | Wang Y | doi: 10.1074/jbc.M113.527671 |
11788888 | Immunohistochemical analysis reveals a protective effect of H-ras expression mediated via apoptosis in node-negative breast cancer patients. | Int J Oncol | 2002 Feb | Schondorf T | - |
18655729 | Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer? | BMC Cancer | 2008 Jul 27 | Kristensen AT | doi: 10.1186/1471-2407-8-213. |
20848283 | The role of K-ras gene mutation in TRAIL-induced apoptosis in pancreatic and lung cancer cell lines. | Cancer Chemother Pharmacol | 2011 Feb | Sahu RP | doi: 10.1007/s00280-010-1463-1 |
23150177 | Lack of mutational events of RAS genes in sporadic thyroid cancer but high risk associated with HRAS T81C single nucleotide polymorphism (case-control study). | Tumour Biol | 2013 Feb | Khan MS | doi: 10.1007/s13277-012-0577-y |
18296105 | Cigarette smoking and KRAS oncogene mutations in sporadic colorectal cancer: results from the Netherlands Cohort Study. | Mutat Res | 2008 Mar 29 | Weijenberg MP | doi: 10.1016/j.mrgentox.2007.12.008 |
26799184 | Comparison of liver oncogenic potential among human RAS isoforms. | Oncotarget | 2016 Feb 9 | Chung SI | doi: 10.18632/oncotarget.6931. |
18677112 | Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras. | Cell Cycle | 2008 Aug | Park Y | - |
21826673 | Allelic loss of susceptibility loci and the occurrence of BRAF and RAS mutations in patients with familial non-medullary thyroid cancer. | J Surg Oncol | 2012 Jan | Na KY | doi: 10.1002/jso.22064 |
23722551 | 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. | Cancer Res | 2013 Jul 15 | Kohli L | doi: 10.1158/0008-5472.CAN-12-3765 |
21336946 | Limited evidence supported the association of HRAS1 polymorphism with breast cancer risk. | Breast Cancer Res Treat | 2011 Jul | Zhang X | doi: 10.1007/s10549-011-1407-4 |
15638373 | Clinical usefulness of K-RAS mutation detection in colorectal cancer and in surgical margins of the colon. | Rocz Akad Med Bialymst | 2004 | Okulczyk B | - |
23168708 | Analysis of p53, K-ras gene mutation & Helicobacter pylori infection in patients with gastric cancer & peptic ulcer disease at a tertiary care hospital in north India. | Indian J Med Res | 2012 Oct | Saxena A | - |
22324744 | DNA alterations of microsatellite DNA, p53, APC and K-ras in Chinese colorectal cancer patients. | Eur J Clin Invest | 2012 Jul | Xu XM | doi: 10.1111/j.1365-2362.2011.02641.x |
20038817 | Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-Ras. | Cancer Biol Ther | 2009 Dec | Navaraj A | - |
21221763 | Current evidence on the relationship between HRAS1 polymorphism and breast cancer risk: a meta-analysis. | Breast Cancer Res Treat | 2011 Jul | Zhang C | doi: 10.1007/s10549-011-1344-2 |
16384911 | RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells. | FASEB J | 2006 Mar | Mei FC | - |
17018607 | Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. | Cancer Res | 2006 Oct 1 | Datta D | - |
26969876 | Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM staging system in differentiated thyroid cancer patients. | Cancer | 2016 May 1 | Song YS | doi: 10.1002/cncr.29934 |
16760302 | Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin. | Ann Oncol | 2006 Jun | Bishehsari F | - |
23561972 | Nicotinamide prohibits proliferation and enhances chemosensitivity of pancreatic cancer cells through deregulating SIRT1 and Ras/Akt pathways. | Pancreatology | 2013 Mar-Apr | Zhang JG | doi: 10.1016/j.pan.2013.01.001 |
19443408 | Mutation status of K-ras, p53 and allelic losses at 9p and 18q are not prognostic markers in patients with pancreatic cancer. | Anticancer Res | 2009 May | Salek C | - |
21808062 | The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal. | J Biol Chem | 2011 Sep 23 | Banerjee P | doi: 10.1074/jbc.M111.248401 |
27165221 | New Gene Profiling in Determination of Breast Cancer Recurrence and Prognosis in Iranian Women. | Asian Pac J Cancer Prev | 2016 | Poorhosseini SM | - |
20413844 | Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition. | Cell Oncol | 2010 Jan 1 | van Houdt WJ | doi: 10.3233/CLO-2010-0521. |
21281602 | Activation of H-Ras and Rac1 correlates with epidermal growth factor-induced invasion in Hs578T and MDA-MB-231 breast carcinoma cells. | Biochem Biophys Res Commun | 2011 Mar 4 | Koh MS | doi: 10.1016/j.bbrc.2011.01.092 |
18021740 | Brain cancer stem-like cell genesis from p53-deficient mouse astrocytes by oncogenic Ras. | Biochem Biophys Res Commun | 2008 Jan 18 | Lee JS | - |
26413934 | A novel role for flotillin-1 in H-Ras-regulated breast cancer aggressiveness. | Int J Cancer | 2016 Mar 1 | Koh M | doi: 10.1002/ijc.29869 |
15950068 | Effects of HRAS oncogene on cell cycle progression in a cervical cancer-derived cell line. | Arch Med Res | 2005 Jul-Aug | Cordova-Alarcon E | - |
22433386 | H-ras mutation detection in bladder cancer by COLD-PCR analysis and direct sequencing. | Urol Int | 2012 | Wang AX | doi: 10.1159/000336132 |
23726918 | Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells. | Biochem Biophys Res Commun | 2013 Jun 28 | Ono M | doi: 10.1016/j.bbrc.2013.05.071 |
24169525 | HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome. | Eur J Hum Genet | 2014 Jun | Beukers W | doi: 10.1038/ejhg.2013.251 |
19029954 | Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells. | Oncogene | 2009 Feb 5 | Sui X | doi: 10.1038/onc.2008.423 |
22865907 | Somatic RAS mutations occur in a large proportion of sporadic RET-negative medullary thyroid carcinomas and extend to a previously unidentified exon. | J Clin Endocrinol Metab | 2012 Oct | Boichard A | doi: 10.1210/jc.2012-2092 |
21825040 | Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras. | Clin Cancer Res | 2011 Oct 1 | Eggers JP | doi: 10.1158/1078-0432.CCR-10-2288 |
20720444 | DNA mutational differences in cytological specimens from pancreatic cancer and cholangiocarcinoma. | Pancreatology | 2010 | Fasanella KE | doi: 10.1159/000318807 |
21120662 | Changes in expression of oncogenes and TP53 tumour suppressor gene as biomarkers in head and neck cancers. | Eur Arch Otorhinolaryngol | 2011 Jul | Szanyi I | doi: 10.1007/s00405-010-1425-6 |
20108024 | Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation. | Cancer Metastasis Rev | 2010 Mar | Suda K | doi: 10.1007/s10555-010-9209-4. |
18676755 | K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. | Clin Cancer Res | 2008 Aug 1 | Etienne-Grimaldi MC | doi: 10.1158/1078-0432.CCR-07-4906. |
21411223 | Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib. | Cancer Lett | 2011 Jul 1 | Luwor RB | doi: 10.1016/j.canlet.2011.02.035 |
18621636 | Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab alone. | Clin Colorectal Cancer | 2008 May | Freeman DJ | doi: 10.3816/CCC.2008.n.024. |
23617461 | Role of β4 integrin in HER-3-negative, K-RAS wild-type metastatic colorectal tumors receiving cetuximab. | Future Oncol | 2013 Aug | Scartozzi M | doi: 10.2217/fon.13.72 |
21122380 | [Relationship between EGFR and K-ras mutations and clinicopathological characteristics and response to erlotinib treatment in 301 Chinese patients with non-small cell lung cancer]. | Zhonghua Zhong Liu Za Zhi | 2010 Sep | Sun LN | - |
20375073 | Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b. | Carcinogenesis | 2010 Jul | Kwon O | doi: 10.1093/carcin/bgq071 |
24696319 | RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma. | Clin Cancer Res | 2014 Jun 1 | Rampias T | doi: 10.1158/1078-0432.CCR-13-2721 |
19787272 | Association of H-ras polymorphisms and susceptibility to sporadic colon cancer. | Int J Oncol | 2009 Nov | Catela Ivkovic T | - |
27535135 | Classical point mutations of RET, BRAF and RAS oncogenes are not shared in papillary and medullary thyroid cancer occurring simultaneously in the same gland. | J Endocrinol Invest | 2017 Jan | Ciampi R | doi: 10.1007/s40618-016-0526-5 |
28202657 | Deciphering the RAS/ERK pathway in vivo. | Biochem Soc Trans | 2017 Feb 8 | Dorard C | doi: 10.1042/BST20160135. |
27689252 | Clinical, Sonographic, and Pathological Characteristics of RAS-Positive Versus BRAF-Positive Thyroid Carcinoma. | J Clin Endocrinol Metab | 2016 Dec | Kakarmath S | - |
28864536 | Changes in the clinicopathological characteristics and genetic alterations of follicular thyroid cancer. | Eur J Endocrinol | 2017 Dec | Song YS | doi: 10.1530/EJE-17-0456 |