EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000174780 (Gene tree)
Gene ID: 6731
Gene Symbol: SRP72
Alias: N
Full Name: signal recognition particle 72
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 36,346 bases
Position: chr4:56,467,336-56,503,681
Accession: 11303
RBP type: canonical RBP
Summary: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000424576	SRP72	PF08492.12	1.4e-21	1	1
ENSP00000342181	SRP72	PF08492.12	1.6e-21	1	1
ENSP00000495128	SRP72	PF08492.12	1.6e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
1377027	Fluorescence-detected assembly of the signal recognition particle: binding of the two SRP protein heterodimers to SRP RNA is noncooperative.	Biochemistry	1992 Jun 30	Janiak F	-
21073748	Identification of amino acid residues in protein SRP72 required for binding to a kinked 5e motif of the human signal recognition particle RNA.	BMC Mol Biol	2010 Nov 13	Iakhiaeva E	doi: 10.1186/1471-2199-11-83.
18347438	Identification of the RNA binding regions of SRP68/72 and SRP72 by systematic mutagenesis of human SRP RNA.	RNA Biol	2007 Nov	Yin J	-
15588816	Identification of an RNA-binding domain in human SRP72.	J Mol Biol	2005 Jan 28	Iakhiaeva E	-
16672232	Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains.	Protein Sci	2006 Jun	Iakhiaeva E	-
18441046	The 5e motif of eukaryotic signal recognition particle RNA contains a conserved adenosine for the binding of SRP72.	RNA	2008 Jun	Iakhiaeva E	doi: 10.1261/rna.979508
17254600	Protein-induced conformational changes of RNA during the assembly of human signal recognition particle.	J Mol Biol	2007 Mar 16	Menichelli E	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000642900	SRP72-206	3855	XM_024454192	ENSP00000495128	671 (aa)	XP_024309960	O76094
ENST00000505314	SRP72-203	1006	-	ENSP00000425190	335 (aa)	-	D6RDY6
ENST00000510663	SRP72-205	2406	-	ENSP00000424576	610 (aa)	-	O76094
ENST00000646579	SRP72-209	766	-	-	- (aa)	-	-
ENST00000507126	SRP72-204	2235	-	-	- (aa)	-	-
ENST00000646222	SRP72-207	429	-	-	- (aa)	-	-
ENST00000342756	SRP72-201	4136	-	ENSP00000342181	671 (aa)	-	O76094
ENST00000504757	SRP72-202	745	-	ENSP00000473576	220 (aa)	-	R4GNC1
ENST00000646537	SRP72-208	1496	-	-	- (aa)	-	-
ENST00000647432	SRP72-210	778	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000174780's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03060	Protein export	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000174780	Pulmonary Disease, Chronic Obstructive	3.0600000E-007	22837378
ENSG00000174780	Pulmonary Disease, Chronic Obstructive	5.0260000E-007	22837378
ENSG00000174780	Respiratory Function Tests	5E-6	22837378

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000174780	rs12505749	4	56467946	?	Airflow obstruction	22837378		1.27	EFO_0003892

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000174780's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000174780	SRP72	99	76.480	ENSAPOG00000019438	srp72	97	76.351	Acanthochromis_polyacanthus
ENSG00000174780	SRP72	100	98.361	ENSAMEG00000008469	SRP72	99	98.361	Ailuropoda_melanoleuca
ENSG00000174780	SRP72	99	76.269	ENSACIG00000000488	srp72	97	76.147	Amphilophus_citrinellus
ENSG00000174780	SRP72	100	77.198	ENSAOCG00000011256	srp72	98	77.099	Amphiprion_ocellaris
ENSG00000174780	SRP72	100	76.900	ENSAPEG00000001512	srp72	98	76.794	Amphiprion_percula
ENSG00000174780	SRP72	99	73.026	ENSATEG00000006781	srp72	99	78.013	Anabas_testudineus
ENSG00000174780	SRP72	98	85.000	ENSAPLG00000008751	SRP72	96	85.248	Anas_platyrhynchos
ENSG00000174780	SRP72	96	86.090	ENSACAG00000002381	SRP72	96	85.496	Anolis_carolinensis
ENSG00000174780	SRP72	100	97.541	ENSANAG00000020836	-	100	97.541	Aotus_nancymaae
ENSG00000174780	SRP72	99	76.946	ENSACLG00000014617	srp72	97	76.840	Astatotilapia_calliptera
ENSG00000174780	SRP72	97	77.370	ENSAMXG00000004011	srp72	97	77.489	Astyanax_mexicanus
ENSG00000174780	SRP72	100	97.466	ENSBTAG00000010593	SRP72	100	97.466	Bos_taurus
ENSG00000174780	SRP72	100	97.615	ENSCJAG00000017998	SRP72	100	97.615	Callithrix_jacchus
ENSG00000174780	SRP72	100	98.808	ENSCAFG00000002244	SRP72	100	98.808	Canis_familiaris
ENSG00000174780	SRP72	100	98.689	ENSCAFG00020027338	SRP72	100	98.689	Canis_lupus_dingo
ENSG00000174780	SRP72	100	96.509	ENSCHIG00000021465	SRP72	98	95.282	Capra_hircus
ENSG00000174780	SRP72	99	98.358	ENSTSYG00000010571	-	99	98.358	Carlito_syrichta
ENSG00000174780	SRP72	81	91.260	ENSCAPG00000016668	SRP72	93	91.260	Cavia_aperea
ENSG00000174780	SRP72	100	98.361	ENSCPOG00000000218	SRP72	100	98.361	Cavia_porcellus
ENSG00000174780	SRP72	95	97.492	ENSCCAG00000030683	-	95	97.492	Cebus_capucinus
ENSG00000174780	SRP72	99	95.946	ENSCCAG00000030830	-	99	95.946	Cebus_capucinus
ENSG00000174780	SRP72	100	99.553	ENSCATG00000008072	SRP72	100	99.553	Cercocebus_atys
ENSG00000174780	SRP72	97	78.834	ENSCATG00000045359	-	95	78.737	Cercocebus_atys
ENSG00000174780	SRP72	100	97.990	ENSCLAG00000003571	SRP72	100	97.990	Chinchilla_lanigera
ENSG00000174780	SRP72	92	100.000	ENSCSAG00000005079	SRP72	98	93.893	Chlorocebus_sabaeus
ENSG00000174780	SRP72	90	99.153	ENSCHOG00000013240	SRP72	90	99.153	Choloepus_hoffmanni
ENSG00000174780	SRP72	96	86.936	ENSCPBG00000015015	SRP72	98	86.128	Chrysemys_picta_bellii
ENSG00000174780	SRP72	99	38.303	ENSCING00000002417	-	95	41.489	Ciona_intestinalis
ENSG00000174780	SRP72	99	38.760	ENSCSAVG00000011288	-	99	40.541	Ciona_savignyi
ENSG00000174780	SRP72	92	78.884	ENSCANG00000037920	-	98	81.356	Colobus_angolensis_palliatus
ENSG00000174780	SRP72	100	99.553	ENSCANG00000041709	SRP72	100	99.553	Colobus_angolensis_palliatus
ENSG00000174780	SRP72	100	97.466	ENSCGRG00001013548	Srp72	100	97.466	Cricetulus_griseus_chok1gshd
ENSG00000174780	SRP72	94	97.319	ENSCGRG00000003013	Srp72	99	97.319	Cricetulus_griseus_crigri
ENSG00000174780	SRP72	99	77.246	ENSCSEG00000003616	srp72	97	77.454	Cynoglossus_semilaevis
ENSG00000174780	SRP72	91	77.997	ENSCVAG00000001520	srp72	99	77.997	Cyprinodon_variegatus
ENSG00000174780	SRP72	85	77.193	ENSDARG00000014139	srp72	97	77.296	Danio_rerio
ENSG00000174780	SRP72	98	92.237	ENSDNOG00000039012	SRP72	81	92.390	Dasypus_novemcinctus
ENSG00000174780	SRP72	99	96.866	ENSDORG00000000171	Srp72	99	96.866	Dipodomys_ordii
ENSG00000174780	SRP72	99	39.005	FBgn0038810	Srp72	94	40.931	Drosophila_melanogaster
ENSG00000174780	SRP72	100	96.726	ENSETEG00000005191	SRP72	100	96.726	Echinops_telfairi
ENSG00000174780	SRP72	73	61.382	ENSEBUG00000003696	srp72	96	61.633	Eptatretus_burgeri
ENSG00000174780	SRP72	100	98.659	ENSEASG00005017747	SRP72	100	98.659	Equus_asinus_asinus
ENSG00000174780	SRP72	100	98.510	ENSECAG00000006920	SRP72	100	98.510	Equus_caballus
ENSG00000174780	SRP72	99	75.744	ENSELUG00000022415	srp72	97	75.920	Esox_lucius
ENSG00000174780	SRP72	100	98.065	ENSFCAG00000027600	SRP72	100	98.065	Felis_catus
ENSG00000174780	SRP72	96	87.403	ENSFALG00000006713	SRP72	97	86.239	Ficedula_albicollis
ENSG00000174780	SRP72	97	67.285	ENSFDAG00000009793	-	95	66.273	Fukomys_damarensis
ENSG00000174780	SRP72	100	97.615	ENSFDAG00000002014	-	100	97.615	Fukomys_damarensis
ENSG00000174780	SRP72	99	75.744	ENSFHEG00000017652	srp72	90	76.220	Fundulus_heteroclitus
ENSG00000174780	SRP72	97	72.881	ENSGMOG00000005986	srp72	96	73.344	Gadus_morhua
ENSG00000174780	SRP72	96	87.227	ENSGALG00000011403	SRP72	98	86.585	Gallus_gallus
ENSG00000174780	SRP72	99	76.831	ENSGAFG00000017762	srp72	97	77.006	Gambusia_affinis
ENSG00000174780	SRP72	99	75.149	ENSGACG00000016749	srp72	97	75.762	Gasterosteus_aculeatus
ENSG00000174780	SRP72	87	86.082	ENSGAGG00000024611	SRP72	96	86.874	Gopherus_agassizii
ENSG00000174780	SRP72	100	99.404	ENSGGOG00000013234	-	100	99.404	Gorilla_gorilla
ENSG00000174780	SRP72	99	77.096	ENSHBUG00000020723	srp72	97	76.994	Haplochromis_burtoni
ENSG00000174780	SRP72	92	95.567	ENSHGLG00000003950	-	97	93.450	Heterocephalus_glaber_female
ENSG00000174780	SRP72	100	98.063	ENSHGLG00000009791	SRP72	100	98.063	Heterocephalus_glaber_female
ENSG00000174780	SRP72	98	91.908	ENSHGLG00000005029	-	98	91.450	Heterocephalus_glaber_female
ENSG00000174780	SRP72	97	74.046	ENSHGLG00000018597	-	97	74.390	Heterocephalus_glaber_female
ENSG00000174780	SRP72	98	80.467	ENSHGLG00000010633	-	98	89.247	Heterocephalus_glaber_female
ENSG00000174780	SRP72	57	77.168	ENSHGLG00000003496	-	97	77.647	Heterocephalus_glaber_female
ENSG00000174780	SRP72	92	87.192	ENSHGLG00100009346	-	97	79.933	Heterocephalus_glaber_male
ENSG00000174780	SRP72	98	91.908	ENSHGLG00100011236	-	98	91.450	Heterocephalus_glaber_male
ENSG00000174780	SRP72	92	95.074	ENSHGLG00100017133	-	97	93.013	Heterocephalus_glaber_male
ENSG00000174780	SRP72	100	98.063	ENSHGLG00100009021	SRP72	100	98.063	Heterocephalus_glaber_male
ENSG00000174780	SRP72	99	76.912	ENSHCOG00000013760	srp72	97	76.959	Hippocampus_comes
ENSG00000174780	SRP72	99	76.612	ENSIPUG00000000210	srp72	97	76.498	Ictalurus_punctatus
ENSG00000174780	SRP72	100	98.808	ENSSTOG00000007305	SRP72	100	98.808	Ictidomys_tridecemlineatus
ENSG00000174780	SRP72	100	96.731	ENSJJAG00000018324	Srp72	100	96.731	Jaculus_jaculus
ENSG00000174780	SRP72	99	75.934	ENSKMAG00000003776	srp72	97	76.037	Kryptolebias_marmoratus
ENSG00000174780	SRP72	97	78.988	ENSLOCG00000002628	srp72	97	79.109	Lepisosteus_oculatus
ENSG00000174780	SRP72	100	97.765	ENSLAFG00000018307	SRP72	100	97.765	Loxodonta_africana
ENSG00000174780	SRP72	100	99.404	ENSMFAG00000031065	SRP72	100	99.404	Macaca_fascicularis
ENSG00000174780	SRP72	98	79.604	ENSMFAG00000037164	-	97	80.062	Macaca_fascicularis
ENSG00000174780	SRP72	100	99.344	ENSMMUG00000016368	SRP72	100	99.344	Macaca_mulatta
ENSG00000174780	SRP72	94	72.452	ENSMMUG00000021262	-	95	72.160	Macaca_mulatta
ENSG00000174780	SRP72	100	99.404	ENSMNEG00000038065	-	100	99.404	Macaca_nemestrina
ENSG00000174780	SRP72	95	97.962	ENSMLEG00000030140	-	95	97.962	Mandrillus_leucophaeus
ENSG00000174780	SRP72	99	76.453	ENSMAMG00000014989	srp72	87	76.336	Mastacembelus_armatus
ENSG00000174780	SRP72	99	78.841	ENSMZEG00005003325	srp72	97	76.994	Maylandia_zebra
ENSG00000174780	SRP72	95	83.150	ENSMGAG00000008567	SRP72	97	86.947	Meleagris_gallopavo
ENSG00000174780	SRP72	100	97.768	ENSMAUG00000001237	Srp72	100	97.768	Mesocricetus_auratus
ENSG00000174780	SRP72	95	96.865	ENSMICG00000008507	-	95	96.865	Microcebus_murinus
ENSG00000174780	SRP72	100	97.377	ENSMOCG00000020309	Srp72	100	97.377	Microtus_ochrogaster
ENSG00000174780	SRP72	99	74.850	ENSMMOG00000002627	srp72	97	75.307	Mola_mola
ENSG00000174780	SRP72	95	88.119	ENSMODG00000020697	SRP72	98	86.718	Monodelphis_domestica
ENSG00000174780	SRP72	99	76.048	ENSMALG00000003747	srp72	97	76.061	Monopterus_albus
ENSG00000174780	SRP72	100	96.393	MGP_CAROLIEiJ_G0027323	Srp72	100	96.393	Mus_caroli
ENSG00000174780	SRP72	100	96.393	ENSMUSG00000036323	Srp72	100	96.393	Mus_musculus
ENSG00000174780	SRP72	100	96.405	MGP_PahariEiJ_G0017103	Srp72	100	96.405	Mus_pahari
ENSG00000174780	SRP72	100	96.393	MGP_SPRETEiJ_G0028317	Srp72	100	96.393	Mus_spretus
ENSG00000174780	SRP72	100	97.914	ENSMPUG00000004828	SRP72	100	97.914	Mustela_putorius_furo
ENSG00000174780	SRP72	100	96.741	ENSMLUG00000007344	SRP72	100	96.741	Myotis_lucifugus
ENSG00000174780	SRP72	100	96.721	ENSNGAG00000012595	Srp72	100	96.721	Nannospalax_galili
ENSG00000174780	SRP72	99	73.952	ENSNBRG00000014492	srp72	97	73.773	Neolamprologus_brichardi
ENSG00000174780	SRP72	100	93.145	ENSNLEG00000008806	-	100	93.145	Nomascus_leucogenys
ENSG00000174780	SRP72	98	79.787	ENSMEUG00000005164	SRP72	98	79.116	Notamacropus_eugenii
ENSG00000174780	SRP72	96	95.483	ENSOPRG00000012521	SRP72	97	95.413	Ochotona_princeps
ENSG00000174780	SRP72	98	94.817	ENSODEG00000012214	SRP72	98	94.817	Octodon_degus
ENSG00000174780	SRP72	99	76.900	ENSONIG00000001446	srp72	97	76.794	Oreochromis_niloticus
ENSG00000174780	SRP72	89	80.513	ENSOANG00000008562	SRP72	97	71.148	Ornithorhynchus_anatinus
ENSG00000174780	SRP72	100	97.615	ENSOCUG00000012226	SRP72	100	97.615	Oryctolagus_cuniculus
ENSG00000174780	SRP72	99	75.505	ENSORLG00000020418	srp72	97	75.115	Oryzias_latipes
ENSG00000174780	SRP72	99	73.763	ENSORLG00020009138	srp72	96	73.579	Oryzias_latipes_hni
ENSG00000174780	SRP72	99	75.000	ENSORLG00015018251	srp72	97	74.501	Oryzias_latipes_hsok
ENSG00000174780	SRP72	99	74.513	ENSOMEG00000022008	srp72	97	74.962	Oryzias_melastigma
ENSG00000174780	SRP72	100	97.466	ENSOGAG00000003578	SRP72	100	97.466	Otolemur_garnettii
ENSG00000174780	SRP72	100	97.765	ENSOARG00000004329	SRP72	100	97.765	Ovis_aries
ENSG00000174780	SRP72	80	77.799	ENSPPAG00000032490	-	91	76.852	Pan_paniscus
ENSG00000174780	SRP72	100	100.000	ENSPPAG00000042265	SRP72	100	100.000	Pan_paniscus
ENSG00000174780	SRP72	99	70.695	ENSPPAG00000011428	-	95	71.713	Pan_paniscus
ENSG00000174780	SRP72	100	98.212	ENSPPRG00000015991	SRP72	100	98.212	Panthera_pardus
ENSG00000174780	SRP72	100	98.212	ENSPTIG00000018786	SRP72	100	98.212	Panthera_tigris_altaica
ENSG00000174780	SRP72	100	100.000	ENSPTRG00000048466	-	100	100.000	Pan_troglodytes
ENSG00000174780	SRP72	99	72.851	ENSPTRG00000048100	-	95	73.893	Pan_troglodytes
ENSG00000174780	SRP72	80	77.612	ENSPTRG00000043609	-	92	76.079	Pan_troglodytes
ENSG00000174780	SRP72	94	77.953	ENSPANG00000030230	-	97	78.628	Papio_anubis
ENSG00000174780	SRP72	100	99.553	ENSPANG00000005495	SRP72	100	99.553	Papio_anubis
ENSG00000174780	SRP72	93	87.220	ENSPSIG00000003003	SRP72	98	87.220	Pelodiscus_sinensis
ENSG00000174780	SRP72	100	96.439	ENSPEMG00000012828	-	100	96.439	Peromyscus_maniculatus_bairdii
ENSG00000174780	SRP72	96	91.176	ENSPCIG00000000732	SRP72	97	90.673	Phascolarctos_cinereus
ENSG00000174780	SRP72	99	76.831	ENSPFOG00000003480	srp72	97	77.006	Poecilia_formosa
ENSG00000174780	SRP72	99	76.981	ENSPLAG00000020122	srp72	97	77.160	Poecilia_latipinna
ENSG00000174780	SRP72	99	76.532	ENSPMEG00000019988	srp72	97	76.698	Poecilia_mexicana
ENSG00000174780	SRP72	100	75.980	ENSPREG00000006218	srp72	97	76.852	Poecilia_reticulata
ENSG00000174780	SRP72	62	81.414	ENSPPYG00000009152	-	95	80.105	Pongo_abelii
ENSG00000174780	SRP72	100	99.702	ENSPPYG00000014752	-	78	99.702	Pongo_abelii
ENSG00000174780	SRP72	100	96.572	ENSPVAG00000005590	SRP72	100	96.572	Pteropus_vampyrus
ENSG00000174780	SRP72	99	77.395	ENSPNYG00000001916	srp72	97	77.301	Pundamilia_nyererei
ENSG00000174780	SRP72	99	76.981	ENSPNAG00000022424	srp72	97	76.876	Pygocentrus_nattereri
ENSG00000174780	SRP72	100	94.337	ENSRNOG00000002100	LOC108348180	98	94.962	Rattus_norvegicus
ENSG00000174780	SRP72	99	76.355	ENSRBIG00000029328	-	98	75.904	Rhinopithecus_bieti
ENSG00000174780	SRP72	100	97.007	ENSRBIG00000042069	SRP72	100	97.007	Rhinopithecus_bieti
ENSG00000174780	SRP72	100	99.553	ENSRROG00000035704	SRP72	100	99.553	Rhinopithecus_roxellana
ENSG00000174780	SRP72	93	90.836	ENSSHAG00000000614	SRP72	98	87.234	Sarcophilus_harrisii
ENSG00000174780	SRP72	99	78.861	ENSSFOG00015002026	srp72	97	78.802	Scleropages_formosus
ENSG00000174780	SRP72	99	75.750	ENSSMAG00000007639	srp72	97	75.115	Scophthalmus_maximus
ENSG00000174780	SRP72	99	76.866	ENSSDUG00000007345	srp72	96	77.523	Seriola_dumerili
ENSG00000174780	SRP72	99	76.751	ENSSLDG00000021819	srp72	97	76.923	Seriola_lalandi_dorsalis
ENSG00000174780	SRP72	82	93.158	ENSSARG00000005804	SRP72	74	93.158	Sorex_araneus
ENSG00000174780	SRP72	96	86.760	ENSSPUG00000009740	SRP72	97	85.933	Sphenodon_punctatus
ENSG00000174780	SRP72	99	76.497	ENSSPAG00000011565	srp72	97	77.147	Stegastes_partitus
ENSG00000174780	SRP72	99	94.118	ENSSSCG00000008900	SRP72	98	94.207	Sus_scrofa
ENSG00000174780	SRP72	96	87.267	ENSTGUG00000004767	SRP72	97	85.954	Taeniopygia_guttata
ENSG00000174780	SRP72	99	75.862	ENSTRUG00000009831	srp72	97	75.883	Takifugu_rubripes
ENSG00000174780	SRP72	99	77.347	ENSTNIG00000013073	srp72	97	77.252	Tetraodon_nigroviridis
ENSG00000174780	SRP72	90	90.625	ENSTBEG00000007394	SRP72	90	84.746	Tupaia_belangeri
ENSG00000174780	SRP72	94	97.161	ENSTTRG00000010945	SRP72	100	97.161	Tursiops_truncatus
ENSG00000174780	SRP72	66	97.750	ENSUAMG00000001701	SRP72	100	98.421	Ursus_americanus
ENSG00000174780	SRP72	100	98.063	ENSUMAG00000008151	SRP72	100	98.063	Ursus_maritimus
ENSG00000174780	SRP72	100	97.733	ENSVPAG00000000458	SRP72	100	97.733	Vicugna_pacos
ENSG00000174780	SRP72	100	98.659	ENSVVUG00000006020	SRP72	100	98.659	Vulpes_vulpes
ENSG00000174780	SRP72	95	79.278	ENSXETG00000010205	srp72	97	78.905	Xenopus_tropicalis
ENSG00000174780	SRP72	99	76.532	ENSXMAG00000018000	srp72	97	76.805	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005047	signal recognition particle binding	17254600.	IPI	Function
GO:0005515	protein binding	24965446.	IPI	Function
GO:0005783	endoplasmic reticulum	22541560.	IDA	Component
GO:0005786	signal recognition particle, endoplasmic reticulum targeting	21873635.	IBA	Component
GO:0005786	signal recognition particle, endoplasmic reticulum targeting	18089836.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	-	TAS	Process
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	21873635.	IBA	Process
GO:0008312	7S RNA binding	27899666.	IMP	Function
GO:0030911	TPR domain binding	27899666.	IPI	Function
GO:0042493	response to drug	18089836.	IDA	Process
GO:0043022	ribosome binding	27899666.	IMP	Function
GO:0048500	signal recognition particle	27899666.	IDA	Component