EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000176083 (Gene tree)
Gene ID: 257101
Gene Symbol: ZNF683
Alias: MGC33414|Hobit
Full Name: zinc finger protein 683
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 12,902 bases
Position: chr1:26,361,632-26,374,533
Accession: 28495
RBP type: canonical RBP
Summary: ZNF683 (Zinc Finger Protein 683) is a Protein Coding gene. An important paralog of this gene is BCL6.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000344095	zf-C2H2	PF00096.26	3.2e-16	1	3
ENSP00000344095	zf-C2H2	PF00096.26	3.2e-16	2	3
ENSP00000344095	zf-C2H2	PF00096.26	3.2e-16	3	3
ENSP00000384782	zf-C2H2	PF00096.26	2.6e-15	1	3
ENSP00000384782	zf-C2H2	PF00096.26	2.6e-15	2	3
ENSP00000384782	zf-C2H2	PF00096.26	2.6e-15	3	3
ENSP00000388792	zf-C2H2	PF00096.26	2.6e-15	1	3
ENSP00000388792	zf-C2H2	PF00096.26	2.6e-15	2	3
ENSP00000388792	zf-C2H2	PF00096.26	2.6e-15	3	3
ENSP00000344095	zf-met	PF12874.7	1.4e-06	1	1
ENSP00000384782	zf-met	PF12874.7	4.3e-06	1	1
ENSP00000388792	zf-met	PF12874.7	4.3e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000416125	ZNF683-203	853	-	ENSP00000401961	188 (aa)	-	X1WI31
ENST00000454975	ZNF683-208	592	-	ENSP00000412881	154 (aa)	-	Q5T145
ENST00000403843	ZNF683-202	1670	XM_005245828	ENSP00000384782	524 (aa)	XP_005245885	Q8IZ20
ENST00000451801	ZNF683-206	936	-	ENSP00000411290	269 (aa)	-	A0A0A0MT21
ENST00000423508	ZNF683-204	744	-	ENSP00000391584	197 (aa)	-	A0A0A0MSJ7
ENST00000455900	ZNF683-209	1080	-	ENSP00000411289	282 (aa)	-	X1WI32
ENST00000436292	ZNF683-205	1712	XM_005245830	ENSP00000388792	524 (aa)	XP_005245887	Q8IZ20
ENST00000453132	ZNF683-207	662	-	ENSP00000406734	122 (aa)	-	Q5T142
ENST00000349618	ZNF683-201	1610	XM_017000957	ENSP00000344095	504 (aa)	XP_016856446	Q8IZ20

Gene Model

Click here to download ENSG00000176083's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000176083	Fibrinogen	5.06755259128007E-6	17903294
ENSG00000176083	Fibrinogen	3.1609284290016E-7	17903294
ENSG00000176083	Fibrinogen	2.80966344272029E-6	17903294
ENSG00000176083	C-Reactive Protein	6.27973106961988E-9	17903293
ENSG00000176083	Atrial Natriuretic Factor	5.82798663164273E-8	17903293
ENSG00000176083	Citalopram	7.2790000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000176083's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000176083	ZNF683	100	85.714	ENSANAG00000023008	ZNF683	100	85.714	Aotus_nancymaae
ENSG00000176083	ZNF683	97	83.858	ENSCJAG00000009793	ZNF683	99	83.858	Callithrix_jacchus
ENSG00000176083	ZNF683	96	73.101	ENSTSYG00000031856	ZNF683	99	73.101	Carlito_syrichta
ENSG00000176083	ZNF683	100	84.762	ENSCCAG00000016907	ZNF683	100	84.906	Cebus_capucinus
ENSG00000176083	ZNF683	100	92.262	ENSCATG00000044773	ZNF683	100	92.262	Cercocebus_atys
ENSG00000176083	ZNF683	56	93.929	ENSCSAG00000000974	ZNF683	99	93.929	Chlorocebus_sabaeus
ENSG00000176083	ZNF683	100	91.468	ENSCANG00000008348	ZNF683	100	91.468	Colobus_angolensis_palliatus
ENSG00000176083	ZNF683	69	70.000	ENSDNOG00000043822	-	99	71.429	Dasypus_novemcinctus
ENSG00000176083	ZNF683	96	71.173	ENSEASG00005003952	ZNF683	99	73.019	Equus_asinus_asinus
ENSG00000176083	ZNF683	96	73.085	ENSECAG00000015147	ZNF683	91	73.085	Equus_caballus
ENSG00000176083	ZNF683	94	69.247	ENSFCAG00000012809	ZNF683	95	68.944	Felis_catus
ENSG00000176083	ZNF683	100	98.282	ENSGGOG00000007713	ZNF683	100	98.282	Gorilla_gorilla
ENSG00000176083	ZNF683	100	91.865	ENSMFAG00000002715	ZNF683	100	91.865	Macaca_fascicularis
ENSG00000176083	ZNF683	100	92.063	ENSMMUG00000003420	ZNF683	100	92.063	Macaca_mulatta
ENSG00000176083	ZNF683	100	92.063	ENSMLEG00000037471	ZNF683	100	92.063	Mandrillus_leucophaeus
ENSG00000176083	ZNF683	100	92.565	ENSNLEG00000009200	ZNF683	100	90.278	Nomascus_leucogenys
ENSG00000176083	ZNF683	85	60.930	ENSOCUG00000016978	-	98	60.930	Oryctolagus_cuniculus
ENSG00000176083	ZNF683	100	99.046	ENSPPAG00000038727	ZNF683	100	99.046	Pan_paniscus
ENSG00000176083	ZNF683	99	64.552	ENSPPRG00000008941	ZNF683	95	68.530	Panthera_pardus
ENSG00000176083	ZNF683	99	65.314	ENSPTIG00000015019	ZNF683	95	69.565	Panthera_tigris_altaica
ENSG00000176083	ZNF683	100	99.046	ENSPTRG00000000383	ZNF683	100	99.046	Pan_troglodytes
ENSG00000176083	ZNF683	100	92.857	ENSPANG00000022867	ZNF683	100	92.557	Papio_anubis
ENSG00000176083	ZNF683	100	95.992	ENSPPYG00000001685	ZNF683	100	95.992	Pongo_abelii
ENSG00000176083	ZNF683	80	63.309	ENSPCAG00000010624	ZNF683	79	63.309	Procavia_capensis
ENSG00000176083	ZNF683	99	72.862	ENSPCOG00000020299	ZNF683	99	75.000	Propithecus_coquereli
ENSG00000176083	ZNF683	100	63.298	ENSPVAG00000017265	ZNF683	100	60.421	Pteropus_vampyrus
ENSG00000176083	ZNF683	100	91.468	ENSRBIG00000034984	ZNF683	100	91.468	Rhinopithecus_bieti
ENSG00000176083	ZNF683	100	91.667	ENSRROG00000002892	ZNF683	100	91.667	Rhinopithecus_roxellana
ENSG00000176083	ZNF683	100	84.571	ENSSBOG00000031630	ZNF683	100	84.571	Saimiri_boliviensis_boliviensis
ENSG00000176083	ZNF683	95	69.679	ENSSSCG00000040579	ZNF683	99	74.000	Sus_scrofa

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0002250	adaptive immune response	-	IEA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0010468	regulation of gene expression	-	ISS	Process
GO:0032823	regulation of natural killer cell differentiation	-	ISS	Process
GO:0032826	regulation of natural killer cell differentiation involved in immune response	-	ISS	Process
GO:0033082	regulation of extrathymic T cell differentiation	-	ISS	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0051136	regulation of NK T cell differentiation	-	ISS	Process
GO:1990841	promoter-specific chromatin binding	-	ISS	Function