EuRBPDB

Description

Ensembl ID: ENSG00000176986 (Gene tree)
Gene ID: 9632
Gene Symbol: SEC24C
Alias: KIAA0079
Full Name: SEC24 homolog C, COPII coat complex component
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 27,895 bases
Position: chr10:73,744,281-73,772,175
Accession: 10705
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000465076	SEC24C-203	4668	-	ENSP00000437000	1042 (aa)	-	G5EA31
ENST00000635550	SEC24C-207	3424	-	ENSP00000489351	180 (aa)	-	A0A0U1RR58
ENST00000496827	SEC24C-205	948	-	-	- (aa)	-	-
ENST00000477008	SEC24C-204	660	-	-	- (aa)	-	-
ENST00000634508	SEC24C-206	549	-	ENSP00000489340	183 (aa)	-	A0A0U1RR49
ENST00000345254	SEC24C-202	4433	XM_011540380	ENSP00000321845	1094 (aa)	XP_011538682	P53992
ENST00000339365	SEC24C-201	4513	XM_011540381	ENSP00000343405	1094 (aa)	XP_011538683	P53992

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa04141	Protein processing in endoplasmic reticulum	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000176986	rs35972789	10	73759933	?	Self-rated health	27864402	[NR] unit decrease	0.061	EFO_0004778

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	-	IEA	Component
GO:0000149	SNARE binding	18843296.	IPI	Function
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	-	TAS	Process
GO:0005515	protein binding	10075675.15899885.17428803.18692470.25416956.	IPI	Function
GO:0005789	endoplasmic reticulum membrane	-	TAS	Component
GO:0005829	cytosol	10075675.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006886	intracellular protein transport	-	IEA	Process
GO:0006888	ER to Golgi vesicle-mediated transport	20427317.	IMP	Process
GO:0006888	ER to Golgi vesicle-mediated transport	10329445.	NAS	Process
GO:0006888	ER to Golgi vesicle-mediated transport	-	TAS	Process
GO:0008270	zinc ion binding	18843296.	IDA	Function
GO:0012507	ER to Golgi transport vesicle membrane	-	TAS	Component
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	-	TAS	Process
GO:0030127	COPII vesicle coat	10075675.10329445.17499046.	IDA	Component
GO:0030127	COPII vesicle coat	10214955.	NAS	Component
GO:0048208	COPII vesicle coating	-	TAS	Process
GO:0090110	cargo loading into COPII-coated vesicle	17499046.18843296.	IDA	Process