EuRBPDB

Ensembl ID

ENSG00000177600 (Gene tree)

Gene ID

6181

Gene Symbol

RPLP2

Alias

P2|RPP2|MGC71408|LP2|D11S2243E

Full Name

ribosomal protein lateral stalk subunit P2

Gene Type

protein_coding

Species

Homo_sapiens

Status

confidence

Strand

Plus strand

Length

3,234 bases

Position

chr11:809,647-812,880

Accession

10377

RBP type

canonical RBP

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]