EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000177888 (Gene tree)
Gene ID: 360023
Gene Symbol: ZBTB41
Alias: FRBZ1|FLJ36199|DKFZp686C06120|ZNF924
Full Name: zinc finger and BTB domain containing 41
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 46,863 bases
Position: chr1:197,153,680-197,200,542
Accession: 24819
RBP type: canonical RBP
Summary: ZBTB41 (Zinc Finger And BTB Domain Containing 41) is a Protein Coding gene. An important paralog of this gene is ZBTB17.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	1	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	2	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	3	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	4	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	5	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	6	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	7	8
ENSP00000356375	zf-C2H2	PF00096.26	2.1e-43	8	8
ENSP00000356375	zf-met	PF12874.7	4.7e-07	1	2
ENSP00000356375	zf-met	PF12874.7	4.7e-07	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000367405	ZBTB41-201	8478	XM_011509507	ENSP00000356375	909 (aa)	XP_011507809	Q5SVQ8
ENST00000467322	ZBTB41-202	3779	NR_135153	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000177888's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000177888	Macular Degeneration	8.773741E-9	-
ENSG00000177888	Macular Degeneration	5.63E-6	-
ENSG00000177888	Macular Degeneration	5.063E-5	-
ENSG00000177888	Macular Degeneration	3.64E-11	-
ENSG00000177888	Macular Degeneration	2.05E-13	-
ENSG00000177888	Macular Degeneration	8.05E-12	20385819
ENSG00000177888	Macular Degeneration	2.678E-12	20385819
ENSG00000177888	Platelet Function Tests	4.9100000E-007	-
ENSG00000177888	Platelet Function Tests	1.0768200E-005	-
ENSG00000177888	Platelet Function Tests	3.2657600E-005	-
ENSG00000177888	Platelet Function Tests	2.6100000E-007	-
ENSG00000177888	Platelet Function Tests	2.8000000E-006	-
ENSG00000177888	Platelet Function Tests	7.2800000E-006	-
ENSG00000177888	Platelet Function Tests	2.3900000E-007	-
ENSG00000177888	Platelet Function Tests	2.2800000E-006	-
ENSG00000177888	Platelet Function Tests	6.7500000E-006	-
ENSG00000177888	Platelet Function Tests	3.1000000E-006	-
ENSG00000177888	Blood Coagulation Factors	3E-19	23381943

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000177888	rs7410943	1	197185891	A	End-stage coagulation	23381943	[0.23-0.37] unit increase	0.301	EFO_0004634
ENSG00000177888	rs10754218	1	197195884	G	Blood protein levels	28240269	[0.31-0.49] unit increase	0.4002	EFO_0008149
ENSG00000177888	rs1415212	1	197188764	?	Body mass index	30595370			EFO_0004340
ENSG00000177888	rs10429910	1	197172123	?	Systolic blood pressure	30595370			EFO_0006335

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000177888's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000177888	ZBTB41	94	60.571	ENSAPOG00000015747	zbtb41	95	60.505	Acanthochromis_polyacanthus
ENSG00000177888	ZBTB41	100	97.585	ENSAMEG00000017562	ZBTB41	100	97.585	Ailuropoda_melanoleuca
ENSG00000177888	ZBTB41	65	70.861	ENSACIG00000001767	zbtb41	93	71.096	Amphilophus_citrinellus
ENSG00000177888	ZBTB41	94	58.188	ENSAOCG00000004148	zbtb41	95	58.779	Amphiprion_ocellaris
ENSG00000177888	ZBTB41	94	58.142	ENSAPEG00000003528	zbtb41	85	74.781	Amphiprion_percula
ENSG00000177888	ZBTB41	94	57.849	ENSATEG00000021020	zbtb41	94	57.843	Anabas_testudineus
ENSG00000177888	ZBTB41	99	82.127	ENSAPLG00000007731	ZBTB41	99	82.127	Anas_platyrhynchos
ENSG00000177888	ZBTB41	99	71.585	ENSACAG00000009459	ZBTB41	99	73.115	Anolis_carolinensis
ENSG00000177888	ZBTB41	100	99.010	ENSANAG00000037287	ZBTB41	100	99.010	Aotus_nancymaae
ENSG00000177888	ZBTB41	56	59.259	ENSACLG00000011703	-	53	59.259	Astatotilapia_calliptera
ENSG00000177888	ZBTB41	78	58.235	ENSAMXG00000039622	zbtb41	95	58.508	Astyanax_mexicanus
ENSG00000177888	ZBTB41	100	95.824	ENSBTAG00000002291	ZBTB41	100	95.824	Bos_taurus
ENSG00000177888	ZBTB41	100	99.120	ENSCJAG00000004794	ZBTB41	100	99.120	Callithrix_jacchus
ENSG00000177888	ZBTB41	100	96.703	ENSCAFG00000011381	ZBTB41	100	96.703	Canis_familiaris
ENSG00000177888	ZBTB41	100	96.703	ENSCAFG00020012242	ZBTB41	100	96.703	Canis_lupus_dingo
ENSG00000177888	ZBTB41	100	95.934	ENSCHIG00000011632	ZBTB41	100	95.934	Capra_hircus
ENSG00000177888	ZBTB41	100	97.802	ENSTSYG00000009973	ZBTB41	100	97.802	Carlito_syrichta
ENSG00000177888	ZBTB41	99	96.700	ENSCPOG00000004622	ZBTB41	99	96.700	Cavia_porcellus
ENSG00000177888	ZBTB41	100	98.570	ENSCCAG00000026821	ZBTB41	100	98.570	Cebus_capucinus
ENSG00000177888	ZBTB41	100	99.340	ENSCATG00000040978	ZBTB41	100	99.340	Cercocebus_atys
ENSG00000177888	ZBTB41	99	97.250	ENSCLAG00000010852	ZBTB41	99	97.250	Chinchilla_lanigera
ENSG00000177888	ZBTB41	100	99.340	ENSCSAG00000013610	ZBTB41	100	99.340	Chlorocebus_sabaeus
ENSG00000177888	ZBTB41	100	91.758	ENSCHOG00000004542	ZBTB41	100	91.758	Choloepus_hoffmanni
ENSG00000177888	ZBTB41	99	81.449	ENSCPBG00000028270	ZBTB41	99	81.229	Chrysemys_picta_bellii
ENSG00000177888	ZBTB41	100	99.230	ENSCANG00000035466	ZBTB41	100	99.230	Colobus_angolensis_palliatus
ENSG00000177888	ZBTB41	100	94.292	ENSCGRG00001015855	Zbtb41	99	94.292	Cricetulus_griseus_chok1gshd
ENSG00000177888	ZBTB41	100	94.292	ENSCGRG00000014952	Zbtb41	99	94.292	Cricetulus_griseus_crigri
ENSG00000177888	ZBTB41	68	66.719	ENSCSEG00000011395	zbtb41	94	57.301	Cynoglossus_semilaevis
ENSG00000177888	ZBTB41	93	59.862	ENSCVAG00000008327	zbtb41	95	59.491	Cyprinodon_variegatus
ENSG00000177888	ZBTB41	93	59.545	ENSDARG00000054984	zbtb41	96	60.251	Danio_rerio
ENSG00000177888	ZBTB41	100	77.307	ENSDORG00000001433	Zbtb41	100	88.048	Dipodomys_ordii
ENSG00000177888	ZBTB41	100	91.099	ENSETEG00000001738	ZBTB41	100	91.099	Echinops_telfairi
ENSG00000177888	ZBTB41	100	97.033	ENSEASG00005003240	ZBTB41	100	97.033	Equus_asinus_asinus
ENSG00000177888	ZBTB41	100	96.703	ENSECAG00000009858	ZBTB41	100	96.703	Equus_caballus
ENSG00000177888	ZBTB41	100	88.145	ENSEEUG00000005749	ZBTB41	100	88.145	Erinaceus_europaeus
ENSG00000177888	ZBTB41	70	65.861	ENSELUG00000004343	zbtb41	96	57.020	Esox_lucius
ENSG00000177888	ZBTB41	100	97.582	ENSFCAG00000005026	ZBTB41	100	97.582	Felis_catus
ENSG00000177888	ZBTB41	99	81.360	ENSFALG00000002807	ZBTB41	99	81.360	Ficedula_albicollis
ENSG00000177888	ZBTB41	99	97.140	ENSFDAG00000010904	ZBTB41	99	97.140	Fukomys_damarensis
ENSG00000177888	ZBTB41	64	70.050	ENSFHEG00000016265	zbtb41	95	57.823	Fundulus_heteroclitus
ENSG00000177888	ZBTB41	60	77.523	ENSGMOG00000002344	zbtb41	92	57.729	Gadus_morhua
ENSG00000177888	ZBTB41	99	81.668	ENSGALG00000002305	ZBTB41	99	82.127	Gallus_gallus
ENSG00000177888	ZBTB41	93	56.402	ENSGAFG00000008457	zbtb41	96	64.264	Gambusia_affinis
ENSG00000177888	ZBTB41	96	59.865	ENSGACG00000016102	zbtb41	99	59.843	Gasterosteus_aculeatus
ENSG00000177888	ZBTB41	99	80.525	ENSGAGG00000025218	ZBTB41	99	80.525	Gopherus_agassizii
ENSG00000177888	ZBTB41	100	99.890	ENSGGOG00000004843	ZBTB41	100	99.890	Gorilla_gorilla
ENSG00000177888	ZBTB41	94	56.928	ENSHBUG00000017445	zbtb41	95	57.011	Haplochromis_burtoni
ENSG00000177888	ZBTB41	99	96.810	ENSHGLG00000001087	-	99	96.810	Heterocephalus_glaber_female
ENSG00000177888	ZBTB41	99	94.829	ENSHGLG00100013733	-	99	94.829	Heterocephalus_glaber_male
ENSG00000177888	ZBTB41	94	55.607	ENSHCOG00000001875	zbtb41	97	55.841	Hippocampus_comes
ENSG00000177888	ZBTB41	93	56.410	ENSIPUG00000011967	zbtb41	95	57.175	Ictalurus_punctatus
ENSG00000177888	ZBTB41	100	96.374	ENSJJAG00000004740	Zbtb41	100	96.374	Jaculus_jaculus
ENSG00000177888	ZBTB41	94	58.728	ENSKMAG00000004732	zbtb41	95	59.054	Kryptolebias_marmoratus
ENSG00000177888	ZBTB41	93	59.414	ENSLBEG00000009419	zbtb41	98	59.305	Labrus_bergylta
ENSG00000177888	ZBTB41	99	64.897	ENSLACG00000003626	ZBTB41	100	64.897	Latimeria_chalumnae
ENSG00000177888	ZBTB41	99	67.462	ENSLOCG00000007514	zbtb41	99	67.137	Lepisosteus_oculatus
ENSG00000177888	ZBTB41	99	94.883	ENSLAFG00000012902	ZBTB41	99	94.883	Loxodonta_africana
ENSG00000177888	ZBTB41	100	99.340	ENSMFAG00000042390	ZBTB41	100	99.340	Macaca_fascicularis
ENSG00000177888	ZBTB41	100	99.340	ENSMNEG00000042671	ZBTB41	100	99.340	Macaca_nemestrina
ENSG00000177888	ZBTB41	100	99.340	ENSMLEG00000035413	ZBTB41	100	99.340	Mandrillus_leucophaeus
ENSG00000177888	ZBTB41	96	58.262	ENSMAMG00000002166	zbtb41	89	67.504	Mastacembelus_armatus
ENSG00000177888	ZBTB41	70	68.470	ENSMZEG00005007394	zbtb41	96	67.477	Maylandia_zebra
ENSG00000177888	ZBTB41	99	78.485	ENSMGAG00000005700	ZBTB41	99	78.947	Meleagris_gallopavo
ENSG00000177888	ZBTB41	100	94.524	ENSMAUG00000000806	Zbtb41	100	94.524	Mesocricetus_auratus
ENSG00000177888	ZBTB41	100	96.813	ENSMICG00000043415	ZBTB41	100	96.813	Microcebus_murinus
ENSG00000177888	ZBTB41	100	93.743	ENSMOCG00000001873	Zbtb41	100	93.743	Microtus_ochrogaster
ENSG00000177888	ZBTB41	71	52.430	ENSMMOG00000018454	zbtb41	92	56.667	Mola_mola
ENSG00000177888	ZBTB41	100	88.512	ENSMODG00000012684	ZBTB41	100	88.512	Monodelphis_domestica
ENSG00000177888	ZBTB41	95	59.977	ENSMALG00000005808	zbtb41	93	59.977	Monopterus_albus
ENSG00000177888	ZBTB41	100	93.956	MGP_CAROLIEiJ_G0014667	Zbtb41	100	94.385	Mus_caroli
ENSG00000177888	ZBTB41	100	93.626	ENSMUSG00000033964	Zbtb41	100	94.082	Mus_musculus
ENSG00000177888	ZBTB41	100	93.736	MGP_PahariEiJ_G0027903	Zbtb41	100	94.082	Mus_pahari
ENSG00000177888	ZBTB41	100	93.846	MGP_SPRETEiJ_G0015474	Zbtb41	100	93.930	Mus_spretus
ENSG00000177888	ZBTB41	100	97.473	ENSMPUG00000010318	ZBTB41	100	97.473	Mustela_putorius_furo
ENSG00000177888	ZBTB41	100	82.796	ENSMLUG00000016964	ZBTB41	100	83.226	Myotis_lucifugus
ENSG00000177888	ZBTB41	100	93.736	ENSNGAG00000007406	Zbtb41	100	93.846	Nannospalax_galili
ENSG00000177888	ZBTB41	66	67.157	ENSNBRG00000005175	zbtb41	99	63.181	Neolamprologus_brichardi
ENSG00000177888	ZBTB41	100	99.340	ENSNLEG00000018056	ZBTB41	100	99.340	Nomascus_leucogenys
ENSG00000177888	ZBTB41	96	94.531	ENSOPRG00000016041	ZBTB41	90	94.531	Ochotona_princeps
ENSG00000177888	ZBTB41	99	96.810	ENSODEG00000013022	ZBTB41	99	96.810	Octodon_degus
ENSG00000177888	ZBTB41	94	59.749	ENSONIG00000010729	zbtb41	98	60.227	Oreochromis_niloticus
ENSG00000177888	ZBTB41	60	87.468	ENSOANG00000006270	-	98	87.468	Ornithorhynchus_anatinus
ENSG00000177888	ZBTB41	100	96.813	ENSOCUG00000014765	ZBTB41	100	96.813	Oryctolagus_cuniculus
ENSG00000177888	ZBTB41	94	57.159	ENSORLG00000009152	zbtb41	93	67.980	Oryzias_latipes
ENSG00000177888	ZBTB41	95	56.052	ENSORLG00020012229	zbtb41	99	56.066	Oryzias_latipes_hni
ENSG00000177888	ZBTB41	94	56.715	ENSORLG00015007853	zbtb41	86	71.655	Oryzias_latipes_hsok
ENSG00000177888	ZBTB41	94	56.000	ENSOMEG00000006807	zbtb41	96	55.667	Oryzias_melastigma
ENSG00000177888	ZBTB41	99	94.286	ENSOGAG00000012893	ZBTB41	100	94.286	Otolemur_garnettii
ENSG00000177888	ZBTB41	100	95.934	ENSOARG00000015070	ZBTB41	100	95.934	Ovis_aries
ENSG00000177888	ZBTB41	100	100.000	ENSPPAG00000029179	ZBTB41	100	100.000	Pan_paniscus
ENSG00000177888	ZBTB41	100	97.582	ENSPPRG00000001901	ZBTB41	100	97.582	Panthera_pardus
ENSG00000177888	ZBTB41	100	97.582	ENSPTIG00000017687	ZBTB41	100	97.582	Panthera_tigris_altaica
ENSG00000177888	ZBTB41	100	100.000	ENSPTRG00000001808	ZBTB41	100	100.000	Pan_troglodytes
ENSG00000177888	ZBTB41	99	99.339	ENSPANG00000012545	ZBTB41	100	99.339	Papio_anubis
ENSG00000177888	ZBTB41	93	62.025	ENSPKIG00000018092	zbtb41	94	61.521	Paramormyrops_kingsleyae
ENSG00000177888	ZBTB41	99	77.168	ENSPSIG00000012859	ZBTB41	99	77.168	Pelodiscus_sinensis
ENSG00000177888	ZBTB41	94	54.577	ENSPMGG00000009297	zbtb41	96	54.157	Periophthalmus_magnuspinnatus
ENSG00000177888	ZBTB41	100	94.731	ENSPEMG00000015763	Zbtb41	100	94.731	Peromyscus_maniculatus_bairdii
ENSG00000177888	ZBTB41	100	89.290	ENSPCIG00000021408	ZBTB41	100	89.290	Phascolarctos_cinereus
ENSG00000177888	ZBTB41	93	56.793	ENSPFOG00000006537	zbtb41	100	58.710	Poecilia_formosa
ENSG00000177888	ZBTB41	93	58.810	ENSPLAG00000009179	zbtb41	94	57.986	Poecilia_latipinna
ENSG00000177888	ZBTB41	93	58.440	ENSPMEG00000015216	zbtb41	95	57.191	Poecilia_mexicana
ENSG00000177888	ZBTB41	93	57.494	ENSPREG00000005852	zbtb41	90	57.254	Poecilia_reticulata
ENSG00000177888	ZBTB41	100	99.670	ENSPPYG00000000388	ZBTB41	100	99.670	Pongo_abelii
ENSG00000177888	ZBTB41	100	96.484	ENSPCOG00000018536	ZBTB41	100	96.484	Propithecus_coquereli
ENSG00000177888	ZBTB41	61	87.103	ENSPVAG00000016998	ZBTB41	100	87.103	Pteropus_vampyrus
ENSG00000177888	ZBTB41	94	60.939	ENSPNYG00000002412	zbtb41	95	61.117	Pundamilia_nyererei
ENSG00000177888	ZBTB41	94	59.132	ENSPNAG00000016034	zbtb41	95	59.725	Pygocentrus_nattereri
ENSG00000177888	ZBTB41	100	94.176	ENSRNOG00000011137	Zbtb41	100	94.176	Rattus_norvegicus
ENSG00000177888	ZBTB41	100	96.296	ENSRBIG00000033734	ZBTB41	100	96.296	Rhinopithecus_bieti
ENSG00000177888	ZBTB41	100	99.120	ENSRROG00000031190	ZBTB41	100	99.120	Rhinopithecus_roxellana
ENSG00000177888	ZBTB41	100	99.120	ENSSBOG00000028137	ZBTB41	100	99.120	Saimiri_boliviensis_boliviensis
ENSG00000177888	ZBTB41	100	86.245	ENSSHAG00000005014	ZBTB41	100	86.245	Sarcophilus_harrisii
ENSG00000177888	ZBTB41	93	64.277	ENSSFOG00015011752	zbtb41	94	64.393	Scleropages_formosus
ENSG00000177888	ZBTB41	94	58.997	ENSSMAG00000008907	zbtb41	99	65.588	Scophthalmus_maximus
ENSG00000177888	ZBTB41	94	59.560	ENSSDUG00000009223	zbtb41	95	59.890	Seriola_dumerili
ENSG00000177888	ZBTB41	94	58.562	ENSSLDG00000021177	zbtb41	95	59.184	Seriola_lalandi_dorsalis
ENSG00000177888	ZBTB41	61	90.841	ENSSARG00000004217	ZBTB41	100	90.841	Sorex_araneus
ENSG00000177888	ZBTB41	99	79.057	ENSSPUG00000017690	ZBTB41	99	79.057	Sphenodon_punctatus
ENSG00000177888	ZBTB41	96	59.888	ENSSPAG00000002990	zbtb41	96	59.732	Stegastes_partitus
ENSG00000177888	ZBTB41	100	95.270	ENSSSCG00000010897	ZBTB41	100	95.270	Sus_scrofa
ENSG00000177888	ZBTB41	99	81.229	ENSTGUG00000004282	ZBTB41	100	81.229	Taeniopygia_guttata
ENSG00000177888	ZBTB41	99	55.303	ENSTRUG00000009203	zbtb41	99	55.340	Takifugu_rubripes
ENSG00000177888	ZBTB41	92	55.297	ENSTNIG00000007805	zbtb41	99	57.512	Tetraodon_nigroviridis
ENSG00000177888	ZBTB41	100	96.154	ENSTTRG00000008689	ZBTB41	100	96.154	Tursiops_truncatus
ENSG00000177888	ZBTB41	100	97.692	ENSUAMG00000018602	ZBTB41	100	97.692	Ursus_americanus
ENSG00000177888	ZBTB41	100	97.692	ENSUMAG00000025358	ZBTB41	100	97.692	Ursus_maritimus
ENSG00000177888	ZBTB41	100	94.615	ENSVPAG00000006551	ZBTB41	100	94.615	Vicugna_pacos
ENSG00000177888	ZBTB41	100	96.703	ENSVVUG00000003465	ZBTB41	100	96.703	Vulpes_vulpes
ENSG00000177888	ZBTB41	99	64.004	ENSXETG00000009952	zbtb41	100	64.004	Xenopus_tropicalis
ENSG00000177888	ZBTB41	71	65.701	ENSXCOG00000007499	zbtb41	85	72.456	Xiphophorus_couchianus
ENSG00000177888	ZBTB41	68	66.615	ENSXMAG00000022434	zbtb41	86	72.456	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function