EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000179115 (Gene tree)
Gene ID: 2193
Gene Symbol: FARSA
Alias: CML33|FARSL|FARSLA
Full Name: phenylalanyl-tRNA synthetase subunit alpha
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 11,568 bases
Position: chr19:12,922,470-12,934,037
Accession: 3592
RBP type: canonical RBP
Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000396548	tRNA-synt_2d	PF01409.20	5.3e-90	1	1
ENSP00000320309	tRNA-synt_2d	PF01409.20	6.2e-90	1	1
ENSP00000468051	tRNA-synt_2d	PF01409.20	7.4e-90	1	1
ENSP00000467384	tRNA-synt_2d	PF01409.20	7.5e-80	1	1
ENSP00000468384	tRNA-synt_2d	PF01409.20	1.1e-37	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000588025	FARSA-207	2057	-	ENSP00000468051	548 (aa)	-	K7ER00
ENST00000314606	FARSA-201	1814	XM_024451419	ENSP00000320309	508 (aa)	XP_024307187	Q9Y285
ENST00000587488	FARSA-205	514	-	ENSP00000468384	159 (aa)	-	K7ERS0
ENST00000588965	FARSA-208	1831	-	-	- (aa)	-	-
ENST00000593021	FARSA-210	1135	-	ENSP00000467384	378 (aa)	-	K7EPH2
ENST00000592662	FARSA-209	864	-	-	- (aa)	-	-
ENST00000586146	FARSA-203	1707	-	ENSP00000468068	235 (aa)	-	K7ER16
ENST00000423140	FARSA-202	1720	-	ENSP00000396548	477 (aa)	-	Q9Y285
ENST00000586280	FARSA-204	803	-	-	- (aa)	-	-
ENST00000587981	FARSA-206	521	-	ENSP00000465402	168 (aa)	-	K7EK06

Gene Model

Click here to download ENSG00000179115's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00970	Aminoacyl-tRNA biosynthesis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000179115	Antibodies	8E-6	24324551
ENSG00000179115	Trypanosoma cruzi	8E-6	24324551

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000179115	rs73925236	19	12926896	A	Red blood cell count	27863252	[0.056-0.095] unit increase	0.07515767	EFO_0004305
ENSG00000179115	rs62109865	19	12926920	?	Antibody status in Tripanosoma cruzi seropositivity	24324551			EFO_0004556\|EFO_0005530
ENSG00000179115	rs111757774	19	12931815	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000179115's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000179115	FARSA	99	78.443	ENSAPOG00000011465	farsa	100	77.062	Acanthochromis_polyacanthus
ENSG00000179115	FARSA	99	96.407	ENSAMEG00000012446	FARSA	100	94.488	Ailuropoda_melanoleuca
ENSG00000179115	FARSA	99	71.856	ENSACIG00000020499	farsa	100	72.636	Amphilophus_citrinellus
ENSG00000179115	FARSA	99	77.844	ENSAOCG00000000581	farsa	100	76.660	Amphiprion_ocellaris
ENSG00000179115	FARSA	99	77.844	ENSAPEG00000017695	farsa	100	76.861	Amphiprion_percula
ENSG00000179115	FARSA	98	63.655	ENSATEG00000012633	farsa	100	63.655	Anabas_testudineus
ENSG00000179115	FARSA	98	74.200	ENSATEG00000012807	farsa	100	74.200	Anabas_testudineus
ENSG00000179115	FARSA	99	82.036	ENSACAG00000017166	FARSA	88	77.055	Anolis_carolinensis
ENSG00000179115	FARSA	100	96.850	ENSANAG00000037420	FARSA	100	96.850	Aotus_nancymaae
ENSG00000179115	FARSA	99	78.443	ENSACLG00000001716	farsa	100	77.062	Astatotilapia_calliptera
ENSG00000179115	FARSA	99	79.341	ENSAMXG00000037912	farsa	100	78.672	Astyanax_mexicanus
ENSG00000179115	FARSA	99	96.108	ENSBTAG00000021374	FARSA	100	94.488	Bos_taurus
ENSG00000179115	FARSA	86	69.343	WBGene00001497	fars-1	95	60.294	Caenorhabditis_elegans
ENSG00000179115	FARSA	100	95.807	ENSCJAG00000004686	FARSA	100	95.807	Callithrix_jacchus
ENSG00000179115	FARSA	99	96.108	ENSCAFG00000017096	FARSA	100	94.882	Canis_familiaris
ENSG00000179115	FARSA	99	96.108	ENSCAFG00020005315	FARSA	100	94.882	Canis_lupus_dingo
ENSG00000179115	FARSA	99	95.858	ENSCHIG00000022617	FARSA	100	88.694	Capra_hircus
ENSG00000179115	FARSA	90	94.118	ENSTSYG00000002595	FARSA	85	89.787	Carlito_syrichta
ENSG00000179115	FARSA	91	93.261	ENSCAPG00000011353	FARSA	98	93.464	Cavia_aperea
ENSG00000179115	FARSA	100	92.520	ENSCPOG00000000787	FARSA	100	92.520	Cavia_porcellus
ENSG00000179115	FARSA	100	97.047	ENSCCAG00000028176	FARSA	100	97.047	Cebus_capucinus
ENSG00000179115	FARSA	99	93.713	ENSCLAG00000015489	FARSA	100	92.323	Chinchilla_lanigera
ENSG00000179115	FARSA	94	99.161	ENSCSAG00000006530	FARSA	100	99.161	Chlorocebus_sabaeus
ENSG00000179115	FARSA	97	81.138	ENSCPBG00000023915	FARSA	99	80.240	Chrysemys_picta_bellii
ENSG00000179115	FARSA	98	62.575	ENSCING00000002567	-	99	62.575	Ciona_intestinalis
ENSG00000179115	FARSA	98	63.380	ENSCSAVG00000010683	-	98	63.380	Ciona_savignyi
ENSG00000179115	FARSA	100	98.622	ENSCANG00000043649	-	100	98.622	Colobus_angolensis_palliatus
ENSG00000179115	FARSA	100	91.929	ENSCGRG00001019769	Farsa	100	91.929	Cricetulus_griseus_chok1gshd
ENSG00000179115	FARSA	100	91.929	ENSCGRG00000013415	Farsa	100	91.929	Cricetulus_griseus_crigri
ENSG00000179115	FARSA	99	77.844	ENSCSEG00000016214	farsa	96	76.258	Cynoglossus_semilaevis
ENSG00000179115	FARSA	99	76.048	ENSCVAG00000007907	farsa	100	75.855	Cyprinodon_variegatus
ENSG00000179115	FARSA	99	79.940	ENSDARG00000098825	farsa	100	77.867	Danio_rerio
ENSG00000179115	FARSA	96	94.012	ENSDNOG00000032350	FARSA	99	93.840	Dasypus_novemcinctus
ENSG00000179115	FARSA	99	93.713	ENSDORG00000010118	Farsa	100	92.323	Dipodomys_ordii
ENSG00000179115	FARSA	97	62.753	FBgn0030007	alpha-PheRS	99	62.753	Drosophila_melanogaster
ENSG00000179115	FARSA	100	84.843	ENSETEG00000018673	FARSA	100	84.843	Echinops_telfairi
ENSG00000179115	FARSA	98	63.043	ENSEBUG00000008545	farsa	99	67.905	Eptatretus_burgeri
ENSG00000179115	FARSA	98	93.913	ENSEASG00005004093	FARSA	95	83.208	Equus_asinus_asinus
ENSG00000179115	FARSA	100	95.079	ENSECAG00000015139	FARSA	95	95.079	Equus_caballus
ENSG00000179115	FARSA	99	78.443	ENSELUG00000010183	farsa	100	77.264	Esox_lucius
ENSG00000179115	FARSA	99	97.305	ENSFCAG00000023511	FARSA	100	95.669	Felis_catus
ENSG00000179115	FARSA	99	94.012	ENSFDAG00000005987	FARSA	100	92.505	Fukomys_damarensis
ENSG00000179115	FARSA	99	79.042	ENSFHEG00000009382	farsa	94	77.666	Fundulus_heteroclitus
ENSG00000179115	FARSA	99	77.612	ENSGMOG00000018319	farsa	100	76.707	Gadus_morhua
ENSG00000179115	FARSA	99	78.743	ENSGALG00000040258	FARSA	93	73.019	Gallus_gallus
ENSG00000179115	FARSA	99	78.078	ENSGAFG00000014146	farsa	100	77.465	Gambusia_affinis
ENSG00000179115	FARSA	99	78.507	ENSGACG00000006278	farsa	100	76.908	Gasterosteus_aculeatus
ENSG00000179115	FARSA	99	80.539	ENSGAGG00000000753	FARSA	99	80.240	Gopherus_agassizii
ENSG00000179115	FARSA	100	99.213	ENSGGOG00000003418	FARSA	100	99.213	Gorilla_gorilla
ENSG00000179115	FARSA	99	78.443	ENSHBUG00000019852	farsa	100	77.062	Haplochromis_burtoni
ENSG00000179115	FARSA	99	93.413	ENSHGLG00000005213	FARSA	100	92.659	Heterocephalus_glaber_female
ENSG00000179115	FARSA	99	93.713	ENSHGLG00100009586	FARSA	99	93.000	Heterocephalus_glaber_male
ENSG00000179115	FARSA	99	78.443	ENSHCOG00000019548	farsa	100	75.453	Hippocampus_comes
ENSG00000179115	FARSA	99	79.641	ENSIPUG00000007635	farsa	100	77.867	Ictalurus_punctatus
ENSG00000179115	FARSA	99	94.611	ENSSTOG00000008748	FARSA	100	93.097	Ictidomys_tridecemlineatus
ENSG00000179115	FARSA	99	77.844	ENSKMAG00000010698	farsa	100	77.465	Kryptolebias_marmoratus
ENSG00000179115	FARSA	86	81.752	ENSLBEG00000001258	farsa	97	73.882	Labrus_bergylta
ENSG00000179115	FARSA	99	77.844	ENSLBEG00000006757	-	100	76.861	Labrus_bergylta
ENSG00000179115	FARSA	99	80.539	ENSLOCG00000008389	farsa	99	76.667	Lepisosteus_oculatus
ENSG00000179115	FARSA	99	94.910	ENSLAFG00000016154	FARSA	100	92.913	Loxodonta_africana
ENSG00000179115	FARSA	100	99.016	ENSMFAG00000030595	FARSA	100	99.016	Macaca_fascicularis
ENSG00000179115	FARSA	100	99.016	ENSMMUG00000004390	FARSA	100	99.016	Macaca_mulatta
ENSG00000179115	FARSA	100	99.016	ENSMNEG00000043866	FARSA	100	99.016	Macaca_nemestrina
ENSG00000179115	FARSA	100	98.625	ENSMLEG00000029157	FARSA	100	98.625	Mandrillus_leucophaeus
ENSG00000179115	FARSA	99	79.042	ENSMAMG00000010636	farsa	100	77.867	Mastacembelus_armatus
ENSG00000179115	FARSA	99	78.443	ENSMZEG00005002319	farsa	100	77.062	Maylandia_zebra
ENSG00000179115	FARSA	86	84.672	ENSMGAG00000002458	FARSA	100	85.787	Meleagris_gallopavo
ENSG00000179115	FARSA	100	93.110	ENSMAUG00000009188	Farsa	100	93.110	Mesocricetus_auratus
ENSG00000179115	FARSA	99	97.305	ENSMICG00000016272	FARSA	100	96.260	Microcebus_murinus
ENSG00000179115	FARSA	100	93.110	ENSMOCG00000011399	Farsa	100	93.110	Microtus_ochrogaster
ENSG00000179115	FARSA	99	75.449	ENSMMOG00000006287	farsa	100	74.447	Mola_mola
ENSG00000179115	FARSA	99	87.425	ENSMODG00000011519	FARSA	100	86.089	Monodelphis_domestica
ENSG00000179115	FARSA	98	73.843	ENSMALG00000001972	farsa	100	73.843	Monopterus_albus
ENSG00000179115	FARSA	100	92.717	MGP_CAROLIEiJ_G0031312	Farsa	100	92.717	Mus_caroli
ENSG00000179115	FARSA	100	92.520	ENSMUSG00000003808	Farsa	100	92.520	Mus_musculus
ENSG00000179115	FARSA	100	92.323	MGP_PahariEiJ_G0022917	Farsa	100	92.323	Mus_pahari
ENSG00000179115	FARSA	100	92.717	MGP_SPRETEiJ_G0032431	Farsa	100	92.717	Mus_spretus
ENSG00000179115	FARSA	99	95.808	ENSMPUG00000004400	FARSA	100	94.291	Mustela_putorius_furo
ENSG00000179115	FARSA	99	95.509	ENSMLUG00000012767	FARSA	100	93.701	Myotis_lucifugus
ENSG00000179115	FARSA	86	97.810	ENSNGAG00000018353	Farsa	100	94.851	Nannospalax_galili
ENSG00000179115	FARSA	99	78.743	ENSNBRG00000010063	farsa	100	77.264	Neolamprologus_brichardi
ENSG00000179115	FARSA	100	98.622	ENSNLEG00000012899	FARSA	100	98.622	Nomascus_leucogenys
ENSG00000179115	FARSA	99	86.228	ENSMEUG00000014253	FARSA	100	84.909	Notamacropus_eugenii
ENSG00000179115	FARSA	99	94.311	ENSOPRG00000005004	FARSA	100	92.717	Ochotona_princeps
ENSG00000179115	FARSA	99	93.413	ENSODEG00000010433	FARSA	100	92.323	Octodon_degus
ENSG00000179115	FARSA	99	79.042	ENSONIG00000008075	farsa	100	77.666	Oreochromis_niloticus
ENSG00000179115	FARSA	60	84.375	ENSOANG00000009118	-	100	90.385	Ornithorhynchus_anatinus
ENSG00000179115	FARSA	99	78.144	ENSORLG00000016406	farsa	90	76.258	Oryzias_latipes
ENSG00000179115	FARSA	99	78.443	ENSORLG00020021978	farsa	100	76.459	Oryzias_latipes_hni
ENSG00000179115	FARSA	99	78.614	ENSORLG00015015045	farsa	100	76.459	Oryzias_latipes_hsok
ENSG00000179115	FARSA	99	78.743	ENSOMEG00000017367	farsa	97	76.660	Oryzias_melastigma
ENSG00000179115	FARSA	99	96.407	ENSOGAG00000012243	FARSA	100	95.079	Otolemur_garnettii
ENSG00000179115	FARSA	99	96.707	ENSOARG00000009991	FARSA	94	94.685	Ovis_aries
ENSG00000179115	FARSA	100	99.409	ENSPPAG00000034266	FARSA	100	99.409	Pan_paniscus
ENSG00000179115	FARSA	99	97.305	ENSPPRG00000000346	FARSA	100	95.669	Panthera_pardus
ENSG00000179115	FARSA	93	96.596	ENSPTIG00000011502	FARSA	97	96.596	Panthera_tigris_altaica
ENSG00000179115	FARSA	100	99.606	ENSPTRG00000010550	FARSA	100	99.606	Pan_troglodytes
ENSG00000179115	FARSA	100	98.819	ENSPANG00000010978	FARSA	100	98.742	Papio_anubis
ENSG00000179115	FARSA	99	78.144	ENSPKIG00000007170	farsa	100	77.062	Paramormyrops_kingsleyae
ENSG00000179115	FARSA	88	76.392	ENSPSIG00000012701	FARSA	99	76.149	Pelodiscus_sinensis
ENSG00000179115	FARSA	99	71.257	ENSPMGG00000001401	farsa	100	72.233	Periophthalmus_magnuspinnatus
ENSG00000179115	FARSA	100	92.717	ENSPEMG00000012560	Farsa	100	92.717	Peromyscus_maniculatus_bairdii
ENSG00000179115	FARSA	99	79.641	ENSPMAG00000008453	farsa	100	75.855	Petromyzon_marinus
ENSG00000179115	FARSA	99	87.725	ENSPCIG00000019294	FARSA	100	86.117	Phascolarctos_cinereus
ENSG00000179115	FARSA	99	78.443	ENSPFOG00000001201	farsa	100	77.465	Poecilia_formosa
ENSG00000179115	FARSA	99	78.443	ENSPLAG00000018191	farsa	100	77.465	Poecilia_latipinna
ENSG00000179115	FARSA	99	78.443	ENSPMEG00000013547	farsa	100	77.666	Poecilia_mexicana
ENSG00000179115	FARSA	98	72.837	ENSPREG00000013620	farsa	100	72.837	Poecilia_reticulata
ENSG00000179115	FARSA	100	99.409	ENSPPYG00000009615	FARSA	100	99.409	Pongo_abelii
ENSG00000179115	FARSA	99	94.012	ENSPCAG00000015721	FARSA	100	92.717	Procavia_capensis
ENSG00000179115	FARSA	99	97.904	ENSPCOG00000014412	FARSA	100	96.654	Propithecus_coquereli
ENSG00000179115	FARSA	91	91.549	ENSPVAG00000014714	FARSA	87	94.273	Pteropus_vampyrus
ENSG00000179115	FARSA	99	78.443	ENSPNYG00000002144	farsa	100	77.062	Pundamilia_nyererei
ENSG00000179115	FARSA	99	80.240	ENSPNAG00000000869	farsa	100	78.270	Pygocentrus_nattereri
ENSG00000179115	FARSA	99	94.311	ENSRNOG00000003149	Farsa	100	92.520	Rattus_norvegicus
ENSG00000179115	FARSA	100	98.622	ENSRBIG00000025585	FARSA	100	98.622	Rhinopithecus_bieti
ENSG00000179115	FARSA	100	98.622	ENSRROG00000040046	FARSA	100	98.532	Rhinopithecus_roxellana
ENSG00000179115	FARSA	86	58.993	YFL022C	FRS2	93	50.000	Saccharomyces_cerevisiae
ENSG00000179115	FARSA	100	97.244	ENSSBOG00000031362	FARSA	100	97.244	Saimiri_boliviensis_boliviensis
ENSG00000179115	FARSA	86	90.511	ENSSHAG00000015006	FARSA	100	85.906	Sarcophilus_harrisii
ENSG00000179115	FARSA	99	78.144	ENSSFOG00015014864	farsa	100	75.855	Scleropages_formosus
ENSG00000179115	FARSA	99	78.979	ENSSMAG00000002358	farsa	100	77.062	Scophthalmus_maximus
ENSG00000179115	FARSA	99	77.246	ENSSDUG00000008631	farsa	100	75.855	Seriola_dumerili
ENSG00000179115	FARSA	99	76.946	ENSSLDG00000017108	farsa	100	75.855	Seriola_lalandi_dorsalis
ENSG00000179115	FARSA	98	89.565	ENSSARG00000006579	-	70	91.111	Sorex_araneus
ENSG00000179115	FARSA	98	66.172	ENSSPUG00000012509	FARSA	99	66.809	Sphenodon_punctatus
ENSG00000179115	FARSA	99	77.844	ENSSPAG00000018292	farsa	92	76.861	Stegastes_partitus
ENSG00000179115	FARSA	99	96.407	ENSSSCG00000013745	FARSA	100	94.685	Sus_scrofa
ENSG00000179115	FARSA	98	67.807	ENSTRUG00000010624	farsa	100	67.807	Takifugu_rubripes
ENSG00000179115	FARSA	98	71.630	ENSTNIG00000008330	farsa	100	71.630	Tetraodon_nigroviridis
ENSG00000179115	FARSA	90	91.068	ENSTBEG00000000396	FARSA	100	91.068	Tupaia_belangeri
ENSG00000179115	FARSA	98	92.174	ENSTTRG00000003599	FARSA	87	93.719	Tursiops_truncatus
ENSG00000179115	FARSA	99	96.407	ENSUAMG00000010230	FARSA	100	94.488	Ursus_americanus
ENSG00000179115	FARSA	99	96.407	ENSUMAG00000006110	FARSA	100	94.291	Ursus_maritimus
ENSG00000179115	FARSA	99	96.108	ENSVVUG00000024145	FARSA	100	94.882	Vulpes_vulpes
ENSG00000179115	FARSA	99	77.246	ENSXETG00000007936	farsa	100	76.506	Xenopus_tropicalis
ENSG00000179115	FARSA	98	69.076	ENSXCOG00000015512	farsa	100	69.076	Xiphophorus_couchianus
ENSG00000179115	FARSA	99	77.177	ENSXMAG00000008832	farsa	100	76.258	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	-	IEA	Function
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0004826	phenylalanine-tRNA ligase activity	21873635.	IBA	Function
GO:0004826	phenylalanine-tRNA ligase activity	20223217.	IDA	Function
GO:0005515	protein binding	20223217.21163940.24965446.25416956.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006418	tRNA aminoacylation for protein translation	-	TAS	Process
GO:0006432	phenylalanyl-tRNA aminoacylation	21873635.	IBA	Process
GO:0006432	phenylalanyl-tRNA aminoacylation	20223217.	IDA	Process
GO:0009328	phenylalanine-tRNA ligase complex	21873635.	IBA	Component
GO:0009328	phenylalanine-tRNA ligase complex	20223217.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0051290	protein heterotetramerization	20223217.	IDA	Process